==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR 20-AUG-01 1JT7 . COMPND 2 MOLECULE: ACIDIC FIBROBLAST GROWTH FACTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.R.BRYCH,S.I.BLABER,T.M.LOGAN,M.BLABER . 566 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 25230.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 373 65.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 191 33.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 8 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 20 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 63 11.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 66 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 13 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 22 9 0 8 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1CA H 0 0 144 0, 0.0 3,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -63.1 -37.6 43.9 45.9 2 1DA H + 0 0 126 2,-0.1 2,-0.3 1,-0.0 0, 0.0 0.695 360.0 45.0 -83.5 -18.0 -34.8 41.8 47.5 3 1EA H S S- 0 0 30 1,-0.1 105,-0.0 2,-0.0 104,-0.0 -0.861 83.1 -97.5-130.1 163.3 -33.8 40.3 44.1 4 1FA H - 0 0 55 -2,-0.3 -1,-0.1 1,-0.1 -2,-0.1 -0.021 25.9-132.9 -65.0 170.7 -33.0 41.0 40.5 5 1GA F + 0 0 118 2,-0.1 2,-0.7 87,-0.1 -1,-0.1 -0.108 51.9 135.7-125.8 37.8 -35.5 40.4 37.7 6 2 A N - 0 0 98 87,-0.2 87,-2.8 0, 0.0 -2,-0.0 -0.781 40.0-161.7 -84.3 117.9 -33.6 38.5 35.0 7 3 A L - 0 0 65 -2,-0.7 85,-0.1 85,-0.2 3,-0.1 -0.788 14.3-122.5-106.5 150.9 -36.0 35.8 33.9 8 4 A P - 0 0 14 0, 0.0 3,-0.1 0, 0.0 85,-0.1 -0.356 46.5 -82.0 -79.8 167.6 -35.4 32.6 32.0 9 5 A P - 0 0 111 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.337 67.1 -73.6 -67.5 152.9 -37.2 31.9 28.7 10 6 A G + 0 0 77 1,-0.1 -3,-0.0 -3,-0.1 3,-0.0 -0.210 55.5 163.5 -53.3 130.2 -40.8 30.5 29.1 11 7 A N + 0 0 16 -3,-0.1 39,-0.3 2,-0.1 -1,-0.1 -0.310 44.1 95.4-145.5 55.1 -41.1 26.9 30.2 12 8 A Y + 0 0 71 37,-0.1 38,-0.1 3,-0.1 4,-0.0 0.560 63.2 79.0-118.0 -16.9 -44.6 26.3 31.4 13 9 A K S S+ 0 0 91 36,-0.1 -2,-0.1 2,-0.0 -3,-0.0 0.922 102.3 26.4 -60.3 -46.7 -46.3 24.8 28.3 14 10 A K S S- 0 0 141 1,-0.1 36,-0.3 35,-0.0 34,-0.0 -0.813 91.3 -97.4-118.3 159.9 -44.9 21.4 28.8 15 11 A P - 0 0 49 0, 0.0 126,-0.6 0, 0.0 2,-0.3 -0.262 46.2-161.4 -66.8 159.8 -43.7 19.4 31.7 16 12 A K E -AB 48 140A 30 32,-2.9 32,-2.7 124,-0.2 2,-0.4 -0.957 23.9-122.1-143.6 165.3 -40.0 19.3 32.5 17 13 A L E -AB 47 139A 4 122,-3.3 122,-3.3 -2,-0.3 2,-0.8 -0.838 25.9-141.7-100.8 140.4 -37.1 17.7 34.2 18 14 A L E - B 0 138A 0 28,-0.5 9,-2.5 -2,-0.4 2,-0.6 -0.871 21.9-166.3-108.1 95.8 -35.2 19.9 36.6 19 15 A Y E -CB 26 137A 71 118,-2.4 118,-2.1 -2,-0.8 2,-0.7 -0.744 9.7-149.0 -89.4 119.9 -31.6 18.9 36.2 20 16 A C E >> -CB 25 136A 0 5,-3.5 4,-1.4 -2,-0.6 5,-1.2 -0.779 1.9-158.0 -91.8 116.7 -29.1 20.1 38.7 21 17 A S T 45S+ 0 0 39 114,-1.6 -1,-0.2 -2,-0.7 112,-0.1 0.756 79.2 81.3 -62.6 -24.1 -25.7 20.6 37.2 22 18 A N T 45S- 0 0 29 110,-0.6 -1,-0.2 113,-0.5 95,-0.1 0.937 121.9 -6.7 -45.8 -67.3 -24.1 20.3 40.7 23 19 A G T 45S- 0 0 15 -3,-0.3 -1,-0.2 93,-0.3 -2,-0.2 0.282 102.8-103.7-115.0 7.4 -24.1 16.5 40.9 24 20 A G T <5S+ 0 0 14 -4,-1.4 2,-0.4 1,-0.2 -3,-0.2 0.960 70.2 148.5 69.1 52.1 -26.0 15.8 37.7 25 21 A H E < -C 20 0A 10 -5,-1.2 -5,-3.5 90,-0.1 2,-0.5 -0.903 47.0-130.5-119.8 150.1 -29.3 14.9 39.5 26 22 A F E -CD 19 38A 12 12,-3.5 12,-2.1 -2,-0.4 -7,-0.2 -0.835 35.0-112.2 -96.3 129.5 -32.9 15.2 38.5 27 23 A L E - D 0 37A 0 -9,-2.5 2,-0.4 -2,-0.5 -9,-0.3 -0.302 42.1-169.0 -58.8 142.3 -35.1 16.8 41.2 28 24 A R E - D 0 36A 42 8,-2.9 8,-2.3 34,-0.0 2,-0.6 -0.994 24.0-161.3-143.7 138.2 -37.5 14.3 42.6 29 25 A I E - D 0 35A 0 16,-1.7 6,-0.2 -2,-0.4 36,-0.1 -0.957 21.9-149.4-117.7 114.4 -40.6 14.3 44.8 30 26 A L > - 0 0 40 4,-3.6 3,-3.0 -2,-0.6 4,-0.2 -0.507 28.0-107.5 -83.1 153.3 -41.4 10.9 46.3 31 27 A P T 3 S+ 0 0 79 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.791 118.9 60.5 -46.1 -35.3 -44.9 9.9 47.1 32 28 A D T 3 S- 0 0 120 1,-0.1 3,-0.1 2,-0.1 47,-0.1 0.367 125.1-101.2 -78.5 8.9 -44.2 10.2 50.7 33 29 A G S < S+ 0 0 14 -3,-3.0 46,-1.8 1,-0.3 2,-0.2 0.520 76.0 146.1 86.0 3.6 -43.5 13.9 50.2 34 30 A T - 0 0 57 -4,-0.2 -4,-3.6 44,-0.2 2,-0.4 -0.555 33.3-155.8 -74.1 140.1 -39.7 13.3 50.3 35 31 A V E +D 29 0A 13 42,-0.4 86,-0.5 -6,-0.2 2,-0.2 -0.963 32.8 115.6-121.6 133.8 -37.6 15.5 48.0 36 32 A D E -D 28 0A 36 -8,-2.3 -8,-2.9 -2,-0.4 2,-0.3 -0.859 53.8 -84.3-164.3-160.3 -34.2 14.8 46.6 37 33 A G E -D 27 0A 8 82,-2.4 2,-0.3 -2,-0.2 -10,-0.2 -0.953 29.4-171.7-130.1 147.3 -32.3 14.1 43.4 38 34 A T E -D 26 0A 20 -12,-2.1 -12,-3.5 -2,-0.3 81,-0.1 -0.983 24.7-149.3-135.9 149.8 -31.7 11.1 41.3 39 35 A R S S+ 0 0 156 -2,-0.3 2,-1.1 -14,-0.2 -1,-0.1 0.464 71.0 107.1 -93.2 -2.7 -29.5 10.3 38.4 40 36 A D > - 0 0 74 1,-0.2 3,-2.0 -14,-0.1 -2,-0.1 -0.669 50.1-170.3 -84.2 101.3 -32.0 7.9 37.1 41 37 A R T 3 S+ 0 0 143 -2,-1.1 -1,-0.2 1,-0.3 5,-0.1 0.541 84.8 63.2 -66.4 -6.6 -33.7 9.4 34.0 42 38 A S T 3 S+ 0 0 77 3,-0.0 -1,-0.3 2,-0.0 -2,-0.1 0.539 73.8 122.6 -96.2 -6.3 -36.1 6.6 34.1 43 39 A D X - 0 0 20 -3,-2.0 3,-0.7 1,-0.1 4,-0.0 -0.225 59.0-143.0 -56.1 138.7 -37.6 7.5 37.5 44 40 A Q T 3 S+ 0 0 113 1,-0.2 3,-0.2 2,-0.1 -1,-0.1 0.345 92.4 62.3 -87.6 8.7 -41.3 8.2 37.5 45 41 A H T 3 S+ 0 0 39 1,-0.1 -16,-1.7 19,-0.1 -1,-0.2 0.193 80.4 78.4-118.9 18.7 -41.0 11.0 40.0 46 42 A I < + 0 0 0 -3,-0.7 -28,-0.5 -18,-0.2 2,-0.5 0.319 65.5 102.9-109.6 8.0 -38.9 13.6 38.2 47 43 A Q E -A 17 0A 18 -3,-0.2 16,-2.3 -30,-0.1 17,-0.6 -0.817 49.3-175.1 -97.5 129.5 -41.4 15.2 35.9 48 44 A F E -AE 16 62A 0 -32,-2.7 -32,-2.9 -2,-0.5 2,-0.6 -0.917 24.0-148.6-126.2 151.5 -42.8 18.5 36.9 49 45 A Q E - E 0 61A 56 12,-3.3 12,-2.6 -2,-0.4 2,-0.3 -0.970 21.5-160.9-115.3 118.2 -45.3 20.9 35.7 50 46 A L E - E 0 60A 4 -2,-0.6 2,-0.3 -36,-0.3 10,-0.2 -0.780 10.5-179.3 -99.7 146.5 -44.4 24.5 36.3 51 47 A S E - E 0 59A 46 8,-1.7 8,-1.9 -2,-0.3 2,-0.5 -0.988 25.0-119.9-144.0 151.1 -47.0 27.3 36.3 52 48 A A E + E 0 58A 48 -2,-0.3 6,-0.3 6,-0.2 3,-0.1 -0.823 22.5 175.8 -99.8 126.1 -46.8 31.0 36.9 53 49 A E E S- 0 0 104 4,-2.8 2,-0.3 -2,-0.5 -1,-0.2 0.875 82.6 -6.9 -85.1 -45.0 -48.8 32.7 39.7 54 50 A S E > S- E 0 57A 64 3,-1.0 3,-2.6 0, 0.0 -1,-0.4 -0.843 107.6 -61.6-139.4 167.3 -47.4 36.1 39.0 55 51 A V T 3 S+ 0 0 106 1,-0.3 3,-0.1 -2,-0.3 -3,-0.0 -0.396 128.4 3.1 -59.6 124.9 -44.7 37.1 36.6 56 52 A G T 3 S+ 0 0 4 1,-0.2 35,-2.1 -2,-0.1 2,-0.5 0.469 109.3 107.6 80.0 -0.2 -41.6 35.3 37.8 57 53 A E E < +EF 54 90A 28 -3,-2.6 -4,-2.8 33,-0.2 -3,-1.0 -0.959 49.0 179.0-112.7 124.9 -43.5 33.5 40.6 58 54 A V E -EF 52 89A 0 31,-2.9 31,-2.3 -2,-0.5 2,-0.4 -0.856 31.5-142.1-130.9 164.2 -44.1 29.8 40.1 59 55 A Y E -E 51 0A 32 -8,-1.9 -8,-1.7 -2,-0.3 2,-0.6 -0.872 19.1-150.9-110.0 143.4 -45.5 26.5 41.5 60 56 A I E -E 50 0A 0 27,-0.4 9,-3.1 -2,-0.4 2,-0.5 -0.949 21.2-175.7-121.7 103.3 -43.5 23.4 40.8 61 57 A K E -EG 49 68A 59 -12,-2.6 -12,-3.3 -2,-0.6 2,-0.3 -0.900 26.4-125.4-113.0 132.5 -45.9 20.4 40.7 62 58 A S E > -E 48 0A 0 5,-2.9 4,-2.2 -2,-0.5 -14,-0.2 -0.511 13.0-154.9 -69.9 125.8 -45.1 16.7 40.3 63 59 A T T 4 S+ 0 0 64 -16,-2.3 -1,-0.2 -2,-0.3 -15,-0.1 0.816 92.7 50.0 -71.6 -29.9 -47.0 15.3 37.4 64 60 A E T 4 S+ 0 0 106 -17,-0.6 -1,-0.2 -20,-0.1 -19,-0.1 0.929 129.0 15.6 -73.2 -50.0 -46.9 11.8 38.9 65 61 A T T 4 S- 0 0 43 -36,-0.1 -2,-0.2 2,-0.1 -1,-0.1 0.627 89.4-127.9-102.3 -19.1 -48.1 12.6 42.4 66 62 A G < + 0 0 23 -4,-2.2 -3,-0.1 1,-0.3 2,-0.1 0.451 59.4 145.1 83.8 -2.3 -49.7 16.1 42.1 67 63 A Q - 0 0 2 -38,-0.1 -5,-2.9 -6,-0.1 2,-0.4 -0.417 45.3-130.4 -72.4 145.6 -47.5 17.3 45.1 68 64 A Y E -GH 61 80A 47 12,-3.1 12,-3.2 -7,-0.2 -7,-0.2 -0.799 19.2-117.1 -98.4 135.8 -46.1 20.8 45.1 69 65 A L E + H 0 79A 0 -9,-3.1 -9,-0.3 -2,-0.4 2,-0.3 -0.452 47.9 167.1 -65.8 137.1 -42.5 21.6 45.8 70 66 A A E - H 0 78A 0 8,-2.4 8,-3.2 -2,-0.1 2,-0.4 -0.981 33.0-140.6-150.9 162.2 -42.3 23.6 49.0 71 67 A M E - H 0 77A 0 15,-1.9 6,-0.2 -2,-0.3 34,-0.1 -0.995 25.1-141.3-129.9 123.7 -39.8 24.8 51.6 72 68 A D > - 0 0 34 4,-2.8 3,-2.1 -2,-0.4 52,-0.1 -0.055 33.4 -88.6 -77.2 179.2 -40.7 24.9 55.3 73 69 A T T 3 S+ 0 0 79 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.711 127.7 50.0 -60.6 -25.4 -40.0 27.3 58.1 74 70 A D T 3 S- 0 0 22 2,-0.1 -1,-0.3 50,-0.0 -2,-0.0 0.249 123.6-102.8 -98.5 9.9 -36.7 25.6 58.9 75 71 A G S < S+ 0 0 0 -3,-2.1 49,-2.3 1,-0.3 2,-0.4 0.553 73.2 144.6 82.9 9.0 -35.6 25.7 55.3 76 72 A L - 0 0 32 47,-0.2 -4,-2.8 48,-0.1 2,-0.4 -0.678 46.6-131.2 -85.3 131.7 -36.4 22.0 54.6 77 73 A V E +H 71 0A 18 -2,-0.4 -42,-0.4 45,-0.3 2,-0.3 -0.616 38.6 160.1 -81.8 132.2 -37.7 21.2 51.1 78 74 A Y E -H 70 0A 59 -8,-3.2 -8,-2.4 -2,-0.4 2,-0.6 -0.933 42.2-103.0-145.5 169.9 -40.8 19.0 51.0 79 75 A G E -H 69 0A 10 -46,-1.8 2,-0.4 -2,-0.3 -10,-0.2 -0.875 35.0-154.1-101.1 122.0 -43.7 17.9 48.9 80 76 A S E -H 68 0A 12 -12,-3.2 -12,-3.1 -2,-0.6 -47,-0.1 -0.796 16.1-150.1-100.1 135.9 -47.1 19.6 49.7 81 77 A Q S S+ 0 0 134 -2,-0.4 -1,-0.1 -14,-0.2 -48,-0.0 0.833 88.3 32.7 -68.2 -34.2 -50.4 18.1 49.1 82 78 A T S S- 0 0 92 -14,-0.1 2,-0.3 -15,-0.0 -14,-0.1 -0.909 93.0-103.3-124.2 151.8 -52.0 21.5 48.7 83 79 A P + 0 0 59 0, 0.0 2,-0.2 0, 0.0 -13,-0.1 -0.561 52.0 152.7 -77.7 135.3 -50.6 24.7 47.4 84 80 A N > - 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