==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=28-JUN-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 22-MAR-13 4JT8 . COMPND 2 MOLECULE: NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITO . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.DAI . 274 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13131.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 181 66.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 28 10.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 13 4.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 18 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 39 14.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 68 24.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 4 1 1 1 0 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 120 A K 0 0 160 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 103.3 -2.9 59.9 13.1 2 121 A G - 0 0 72 2,-0.0 2,-0.1 0, 0.0 0, 0.0 0.169 360.0 -56.0 90.0 154.3 0.0 57.7 14.0 3 122 A K - 0 0 198 1,-0.1 2,-0.2 236,-0.0 236,-0.1 -0.356 49.6-122.7 -63.0 140.5 2.3 55.3 12.2 4 123 A L - 0 0 34 234,-0.5 2,-0.2 236,-0.4 -1,-0.1 -0.594 31.9-148.4 -73.3 148.0 0.9 52.4 10.2 5 124 A S > - 0 0 52 -2,-0.2 4,-1.6 236,-0.1 5,-0.1 -0.625 28.7 -98.8-112.4 175.1 2.2 49.0 11.4 6 125 A L H > S+ 0 0 16 1,-0.2 4,-2.5 2,-0.2 5,-0.1 0.891 125.6 53.1 -57.2 -40.8 2.9 45.7 9.7 7 126 A Q H > S+ 0 0 125 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.884 104.5 55.9 -62.4 -40.4 -0.5 44.4 10.9 8 127 A D H > S+ 0 0 61 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.849 108.9 46.3 -60.9 -38.6 -2.2 47.5 9.4 9 128 A V H X S+ 0 0 0 -4,-1.6 4,-2.0 2,-0.2 -2,-0.2 0.933 111.4 52.3 -67.7 -45.9 -0.7 46.6 6.0 10 129 A A H X S+ 0 0 2 -4,-2.5 4,-2.5 1,-0.2 -2,-0.2 0.877 109.0 50.6 -54.6 -41.1 -1.7 42.9 6.5 11 130 A E H X S+ 0 0 113 -4,-2.5 4,-1.9 2,-0.2 6,-0.2 0.881 107.0 53.3 -67.2 -40.4 -5.3 44.1 7.3 12 131 A L H <>S+ 0 0 44 -4,-1.6 5,-2.1 2,-0.2 6,-1.4 0.883 112.4 45.2 -60.5 -40.6 -5.5 46.3 4.1 13 132 A I H ><5S+ 0 0 3 -4,-2.0 3,-1.3 2,-0.2 -2,-0.2 0.918 110.0 53.1 -69.5 -45.7 -4.5 43.2 2.0 14 133 A R H 3<5S+ 0 0 148 -4,-2.5 -2,-0.2 1,-0.3 -1,-0.2 0.835 112.2 46.9 -56.6 -34.8 -6.9 40.9 3.8 15 134 A A T 3<5S- 0 0 61 -4,-1.9 -1,-0.3 -5,-0.1 -2,-0.2 0.514 109.0-126.2 -82.2 -9.4 -9.7 43.4 3.0 16 135 A R T < 5S+ 0 0 109 -3,-1.3 -3,-0.2 -4,-0.3 3,-0.1 0.738 75.0 128.9 60.7 23.3 -8.5 43.7 -0.6 17 136 A A S - 0 0 0 173,-1.6 3,-1.7 -2,-0.3 4,-0.3 -0.625 54.1 -58.2-136.1-161.4 16.8 43.1 -4.8 27 146 A A G >> S+ 0 0 31 1,-0.3 3,-1.9 -2,-0.2 4,-0.7 0.792 116.0 73.9 -58.1 -34.8 19.7 40.8 -3.7 28 147 A G G 34 S+ 0 0 23 172,-2.1 -1,-0.3 1,-0.3 3,-0.3 0.714 90.2 57.4 -53.7 -26.4 18.5 40.5 -0.1 29 148 A I G <4 S+ 0 0 0 -3,-1.7 -1,-0.3 171,-0.4 61,-0.2 0.685 106.9 48.2 -81.9 -14.3 15.6 38.2 -1.0 30 149 A S T X4>S+ 0 0 2 -3,-1.9 5,-1.7 -4,-0.3 3,-1.0 0.507 83.4 86.8-106.0 -4.0 17.8 35.6 -2.6 31 150 A T G ><5S+ 0 0 64 -4,-0.7 3,-2.0 -3,-0.3 -1,-0.1 0.904 86.5 57.2 -61.6 -38.8 20.6 35.2 0.1 32 151 A P G 3 5S+ 0 0 60 0, 0.0 -1,-0.2 0, 0.0 -2,-0.1 0.661 99.8 59.6 -67.7 -14.2 18.5 32.5 1.9 33 152 A S G < 5S- 0 0 22 -3,-1.0 53,-0.4 2,-0.2 -2,-0.2 0.460 130.0 -98.8 -85.2 -3.8 18.5 30.5 -1.3 34 153 A G T < 5S+ 0 0 43 -3,-2.0 -3,-0.2 1,-0.2 -4,-0.0 0.633 88.2 121.9 93.8 17.6 22.3 30.5 -1.1 35 154 A I < - 0 0 17 -5,-1.7 -1,-0.2 -8,-0.1 -2,-0.2 -0.922 49.2-153.4-108.8 105.2 23.1 33.3 -3.5 36 155 A P - 0 0 44 0, 0.0 9,-0.3 0, 0.0 2,-0.1 -0.381 33.7 -87.6 -71.9 156.6 25.0 36.0 -1.7 37 156 A D > - 0 0 40 1,-0.1 3,-2.6 7,-0.1 7,-0.1 -0.446 43.5-120.1 -53.6 131.6 25.0 39.7 -2.8 38 157 A F T 3 S+ 0 0 46 1,-0.3 8,-2.2 6,-0.2 9,-0.4 0.751 112.9 52.8 -52.8 -26.8 27.8 39.8 -5.5 39 158 A R T 3 S+ 0 0 171 6,-0.1 -1,-0.3 7,-0.1 -2,-0.1 0.438 76.3 126.8 -90.8 -3.8 29.6 42.4 -3.3 40 159 A S <> - 0 0 38 -3,-2.6 4,-1.8 1,-0.1 7,-0.2 -0.398 68.6-115.0 -57.2 119.8 29.6 40.4 -0.1 41 160 A P T 4 S- 0 0 120 0, 0.0 2,-1.6 0, 0.0 -1,-0.1 -0.341 91.4 -1.5 -56.3 132.9 33.1 40.2 1.2 42 161 A G T 4 S+ 0 0 64 1,-0.2 -2,-0.1 2,-0.1 -3,-0.0 -0.430 138.2 42.2 87.6 -63.1 34.4 36.6 1.1 43 162 A S T 4 S+ 0 0 78 -2,-1.6 -1,-0.2 -6,-0.1 -5,-0.0 0.807 89.5 98.2 -90.6 -33.6 31.3 34.8 -0.2 44 163 A G S >< S- 0 0 0 -4,-1.8 3,-1.2 1,-0.1 -6,-0.2 -0.050 79.8-112.7 -61.4 158.8 30.0 37.1 -3.0 45 164 A L G > S+ 0 0 19 -9,-0.3 3,-2.0 1,-0.2 -6,-0.1 0.890 112.6 58.4 -55.9 -48.4 30.6 36.7 -6.7 46 165 A Y G 3 S+ 0 0 55 -8,-2.2 3,-0.3 1,-0.3 -1,-0.2 0.627 100.1 60.5 -64.0 -12.6 32.8 39.8 -7.1 47 166 A S G < S+ 0 0 64 -3,-1.2 -1,-0.3 -9,-0.4 -2,-0.2 0.152 93.8 66.7 -98.9 16.0 35.2 38.4 -4.5 48 167 A N <> + 0 0 48 -3,-2.0 4,-0.8 1,-0.1 -1,-0.2 -0.353 52.1 139.5-132.9 52.9 36.0 35.3 -6.6 49 168 A L H >>>S+ 0 0 49 -3,-0.3 5,-2.7 1,-0.2 4,-0.8 0.872 75.6 51.3 -64.3 -42.2 37.8 36.7 -9.7 50 169 A Q H >45S+ 0 0 179 1,-0.2 3,-0.6 3,-0.2 -1,-0.2 0.888 105.0 57.7 -60.1 -41.8 40.3 33.8 -9.7 51 170 A Q H 345S+ 0 0 109 1,-0.2 -1,-0.2 2,-0.1 -2,-0.2 0.743 116.2 34.2 -63.8 -25.3 37.5 31.3 -9.6 52 171 A Y H <<5S- 0 0 20 -4,-0.8 -1,-0.2 -3,-0.5 -2,-0.2 0.447 110.0-115.7-107.6 -3.6 36.0 32.8 -12.9 53 172 A D T <<5 + 0 0 120 -4,-0.8 -3,-0.2 -3,-0.6 -4,-0.1 0.900 61.9 155.8 64.8 45.8 39.2 33.8 -14.6 54 173 A L < - 0 0 19 -5,-2.7 -1,-0.2 1,-0.1 -2,-0.1 -0.813 48.0-148.7-105.4 141.8 38.4 37.5 -14.5 55 174 A P S S- 0 0 77 0, 0.0 -1,-0.1 0, 0.0 -6,-0.1 0.790 86.2 -10.1 -72.3 -28.9 40.8 40.5 -14.6 56 175 A Y S > S- 0 0 94 1,-0.1 3,-0.9 -7,-0.1 4,-0.4 -0.960 78.4 -95.7-165.9 161.9 38.4 42.6 -12.4 57 176 A P G > S+ 0 0 34 0, 0.0 3,-1.3 0, 0.0 4,-0.2 0.893 115.6 49.9 -55.9 -54.3 34.8 42.3 -11.0 58 177 A E G > S+ 0 0 87 1,-0.2 3,-2.6 2,-0.1 117,-0.2 0.720 90.1 84.1 -56.2 -27.5 32.8 44.4 -13.6 59 178 A A G X S+ 0 0 0 -3,-0.9 3,-1.5 1,-0.3 -1,-0.2 0.750 78.4 64.6 -53.1 -31.7 34.4 42.4 -16.5 60 179 A I G < S+ 0 0 3 -3,-1.3 -1,-0.3 -4,-0.4 -2,-0.1 0.711 110.7 38.8 -67.3 -17.8 31.9 39.6 -16.3 61 180 A F G < S+ 0 0 13 -3,-2.6 114,-2.4 -4,-0.2 2,-0.4 -0.030 95.1 102.7-122.4 27.0 29.2 42.1 -17.2 62 181 A E <> - 0 0 44 -3,-1.5 4,-2.2 112,-0.2 5,-0.1 -0.943 62.3-144.4-112.9 134.6 31.1 44.1 -19.8 63 182 A L H > S+ 0 0 44 -2,-0.4 4,-2.6 112,-0.4 5,-0.2 0.914 96.5 51.4 -61.8 -48.9 30.5 43.7 -23.6 64 183 A P H > S+ 0 0 105 0, 0.0 4,-1.6 0, 0.0 -1,-0.2 0.929 115.2 43.3 -61.7 -42.1 34.1 44.2 -24.8 65 184 A F H > S+ 0 0 34 2,-0.2 4,-3.1 1,-0.2 -2,-0.2 0.905 111.4 55.8 -63.6 -43.0 35.5 41.7 -22.4 66 185 A F H < S+ 0 0 2 -4,-2.2 -1,-0.2 1,-0.2 -3,-0.2 0.903 108.7 46.7 -54.4 -45.0 32.6 39.3 -23.2 67 186 A F H < S+ 0 0 108 -4,-2.6 -1,-0.2 1,-0.2 -2,-0.2 0.840 113.8 48.3 -71.0 -31.1 33.4 39.4 -26.9 68 187 A H H < S+ 0 0 151 -4,-1.6 -2,-0.2 -5,-0.2 -1,-0.2 0.907 137.3 2.2 -68.5 -44.2 37.1 38.8 -26.1 69 188 A N < + 0 0 39 -4,-3.1 4,-0.4 -5,-0.1 -1,-0.2 -0.731 60.1 176.3-150.2 96.4 36.3 35.9 -23.8 70 189 A P > + 0 0 21 0, 0.0 4,-2.1 0, 0.0 5,-0.2 0.599 63.4 89.9 -73.3 -11.0 32.7 34.7 -23.2 71 190 A K H > S+ 0 0 97 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.834 80.6 51.7 -65.1 -41.6 33.7 31.8 -20.9 72 191 A P H > S+ 0 0 2 0, 0.0 4,-1.8 0, 0.0 3,-0.2 0.946 112.4 47.8 -58.4 -46.4 33.6 33.5 -17.5 73 192 A F H > S+ 0 0 4 -4,-0.4 4,-2.7 1,-0.2 -2,-0.2 0.925 110.6 51.5 -59.8 -44.6 30.1 34.9 -18.1 74 193 A F H X S+ 0 0 10 -4,-2.1 4,-2.4 2,-0.2 -1,-0.2 0.797 104.1 57.8 -64.5 -26.8 28.9 31.4 -19.3 75 194 A T H X S+ 0 0 48 -4,-1.8 4,-1.8 -3,-0.2 -1,-0.2 0.924 109.2 45.2 -62.1 -47.7 30.3 29.9 -16.1 76 195 A L H X S+ 0 0 5 -4,-1.8 4,-2.5 2,-0.2 5,-0.2 0.949 111.5 52.9 -59.3 -48.7 28.0 32.3 -14.2 77 196 A A H X S+ 0 0 0 -4,-2.7 4,-1.9 1,-0.2 -2,-0.2 0.899 106.3 52.9 -52.7 -47.1 25.1 31.4 -16.5 78 197 A K H < S+ 0 0 74 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.912 113.6 43.5 -56.4 -45.2 25.7 27.7 -15.9 79 198 A E H < S+ 0 0 55 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.851 119.7 41.3 -66.6 -37.3 25.5 28.3 -12.1 80 199 A L H < S+ 0 0 11 -4,-2.5 -2,-0.2 -5,-0.1 -1,-0.2 0.563 85.1 118.3 -95.3 -10.8 22.5 30.6 -12.3 81 200 A Y S >< S- 0 0 5 -4,-1.9 3,-1.4 -5,-0.2 4,-0.3 -0.200 81.0 -80.3 -54.8 146.7 20.4 28.8 -14.9 82 201 A P T 3 S+ 0 0 55 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 -0.173 114.5 40.0 -51.7 138.2 17.0 27.5 -13.7 83 202 A G T 3 S+ 0 0 49 2,-0.5 -2,-0.1 -3,-0.1 -3,-0.1 0.084 95.8 80.6 111.2 -19.8 17.1 24.2 -11.7 84 203 A N S < S+ 0 0 85 -3,-1.4 2,-0.3 1,-0.1 -4,-0.1 0.929 92.2 36.9 -84.9 -49.9 20.2 25.0 -9.6 85 204 A Y S S- 0 0 69 -4,-0.3 -2,-0.5 27,-0.2 -1,-0.1 -0.755 76.3-132.4-105.0 151.9 18.9 27.2 -6.8 86 205 A K - 0 0 131 -53,-0.4 28,-0.1 -2,-0.3 32,-0.1 -0.821 20.4-115.9-102.3 141.5 15.5 27.0 -5.0 87 206 A P - 0 0 12 0, 0.0 2,-0.2 0, 0.0 -57,-0.1 -0.388 34.8-146.6 -61.4 152.1 13.1 29.9 -4.4 88 207 A N >> - 0 0 20 -59,-0.2 4,-1.9 -2,-0.0 3,-0.7 -0.487 37.8 -73.3-111.8-171.2 12.7 30.6 -0.7 89 208 A V H 3> S+ 0 0 31 1,-0.3 4,-2.1 2,-0.2 5,-0.1 0.779 128.8 59.9 -56.5 -32.1 9.7 31.8 1.4 90 209 A T H 3> S+ 0 0 0 -61,-0.2 4,-1.4 2,-0.2 -1,-0.3 0.925 106.7 44.8 -63.6 -45.9 10.1 35.3 0.0 91 210 A H H <> S+ 0 0 0 -3,-0.7 4,-1.7 -62,-0.2 -2,-0.2 0.884 113.9 50.2 -64.1 -40.4 9.6 34.1 -3.6 92 211 A Y H X S+ 0 0 14 -4,-1.9 4,-2.3 1,-0.2 -2,-0.2 0.818 104.1 58.8 -71.6 -28.4 6.6 31.9 -2.6 93 212 A F H X S+ 0 0 0 -4,-2.1 4,-2.1 -5,-0.2 -1,-0.2 0.913 108.3 45.4 -60.2 -44.9 5.1 34.9 -0.7 94 213 A L H X S+ 0 0 0 -4,-1.4 4,-1.8 2,-0.2 -2,-0.2 0.841 110.9 53.8 -67.2 -35.2 5.1 36.9 -4.0 95 214 A R H X S+ 0 0 41 -4,-1.7 4,-2.7 2,-0.2 -2,-0.2 0.897 109.1 47.8 -64.5 -42.5 3.7 33.8 -5.9 96 215 A L H X S+ 0 0 2 -4,-2.3 4,-1.5 2,-0.2 -2,-0.2 0.890 108.0 55.8 -64.3 -40.6 0.8 33.6 -3.4 97 216 A L H <>S+ 0 0 0 -4,-2.1 5,-2.3 1,-0.2 6,-0.8 0.881 111.6 44.5 -56.5 -42.1 0.3 37.3 -3.8 98 217 A H H ><5S+ 0 0 40 -4,-1.8 3,-2.2 4,-0.2 -2,-0.2 0.932 109.1 54.4 -66.5 -50.9 -0.1 36.6 -7.6 99 218 A D H 3<5S+ 0 0 78 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.703 106.9 53.5 -58.4 -24.5 -2.3 33.5 -7.1 100 219 A K T 3<5S- 0 0 61 -4,-1.5 -1,-0.3 -5,-0.1 -2,-0.2 0.234 117.8-111.1 -96.8 11.2 -4.7 35.6 -5.0 101 220 A G T < 5S+ 0 0 44 -3,-2.2 -3,-0.2 -5,-0.1 -2,-0.1 0.751 88.2 112.2 68.9 28.3 -5.1 38.3 -7.7 102 221 A L < + 0 0 4 -5,-2.3 -81,-3.0 -6,-0.2 2,-0.6 0.621 46.4 93.5-106.0 -17.9 -3.2 41.0 -5.7 103 222 A L E +a 21 0A 6 -6,-0.8 -81,-0.2 -83,-0.2 3,-0.1 -0.688 36.6 171.2 -87.1 116.4 -0.0 41.4 -7.8 104 223 A L E S- 0 0 26 -83,-2.3 2,-0.3 -2,-0.6 -82,-0.2 0.899 73.4 -21.6 -80.6 -48.9 0.0 44.2 -10.4 105 224 A R E -a 22 0A 41 -84,-1.4 -82,-2.9 84,-0.1 2,-0.6 -0.950 49.0-145.9-163.5 142.4 3.7 43.9 -11.1 106 225 A L E -ac 23 125A 0 18,-2.7 20,-2.4 -2,-0.3 2,-0.6 -0.948 16.9-161.4-112.6 110.5 7.0 42.6 -9.6 107 226 A Y E -ac 24 126A 4 -84,-3.7 -82,-2.4 -2,-0.6 2,-0.4 -0.821 14.4-167.7 -90.8 122.3 10.1 44.6 -10.5 108 227 A T E -ac 25 127A 0 18,-2.7 20,-1.7 -2,-0.6 21,-0.6 -0.942 31.6-173.5-121.5 133.4 13.3 42.6 -9.9 109 228 A Q + 0 0 33 -84,-2.0 2,-0.2 -2,-0.4 -83,-0.2 0.489 65.7 101.8 -87.0 -9.5 16.9 43.7 -9.8 110 229 A N - 0 0 15 -85,-0.2 19,-0.3 1,-0.1 3,-0.2 -0.494 53.0-166.6 -80.7 145.6 17.9 40.0 -9.5 111 230 A I + 0 0 18 -2,-0.2 21,-0.4 1,-0.1 -1,-0.1 0.474 69.4 93.9-103.9 -3.3 19.2 37.9 -12.4 112 231 A D S S- 0 0 13 1,-0.1 -27,-0.2 19,-0.1 -1,-0.1 0.629 82.9-138.6 -66.1 -15.1 18.8 34.5 -10.6 113 232 A G > + 0 0 11 -3,-0.2 4,-1.9 1,-0.1 5,-0.2 0.701 57.0 138.4 68.6 19.1 15.3 34.1 -12.2 114 233 A L H > + 0 0 4 1,-0.2 4,-1.5 2,-0.2 -1,-0.1 0.746 62.7 63.0 -73.8 -22.3 13.9 32.7 -8.9 115 234 A E H 4>S+ 0 0 0 2,-0.2 5,-1.7 1,-0.2 4,-0.3 0.958 108.2 42.5 -61.9 -51.9 10.6 34.7 -9.3 116 235 A R H >45S+ 0 0 85 1,-0.2 3,-1.9 2,-0.2 -2,-0.2 0.912 112.2 53.4 -55.0 -49.4 9.8 32.7 -12.5 117 236 A V H 3<5S+ 0 0 53 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.809 102.4 59.8 -61.0 -28.9 11.0 29.4 -11.0 118 237 A S T 3<5S- 0 0 0 -4,-1.5 -1,-0.3 -3,-0.2 -2,-0.2 0.595 127.3-100.7 -74.3 -11.9 8.5 30.1 -8.1 119 238 A G T < 5S+ 0 0 34 -3,-1.9 -3,-0.2 1,-0.3 -2,-0.1 0.562 73.5 142.4 104.8 11.8 5.7 30.1 -10.7 120 239 A I < - 0 0 3 -5,-1.7 -1,-0.3 2,-0.0 -2,-0.1 -0.760 53.6-120.5 -80.8 122.9 5.1 33.8 -11.3 121 240 A P > - 0 0 49 0, 0.0 3,-1.7 0, 0.0 4,-0.4 -0.309 17.9-114.6 -65.3 149.0 4.3 34.2 -15.1 122 241 A A G > S+ 0 0 40 1,-0.3 3,-1.4 2,-0.2 5,-0.1 0.777 111.3 67.3 -53.0 -33.3 6.6 36.5 -17.2 123 242 A S G 3 S+ 0 0 73 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.772 101.1 48.1 -64.2 -26.2 3.7 39.0 -17.8 124 243 A K G < S+ 0 0 48 -3,-1.7 -18,-2.7 -19,-0.1 2,-0.4 0.540 103.9 84.5 -84.8 -8.3 3.7 39.9 -14.1 125 244 A L E < -c 106 0A 0 -3,-1.4 2,-0.5 -4,-0.4 -18,-0.2 -0.755 51.1-171.0-105.1 139.8 7.5 40.4 -14.1 126 245 A V E -c 107 0A 2 -20,-2.4 -18,-2.7 -2,-0.4 2,-1.3 -0.901 12.0-166.1-120.0 99.8 9.8 43.2 -15.0 127 246 A E E > -c 108 0A 18 -2,-0.5 3,-1.6 -20,-0.2 -18,-0.1 -0.714 8.0-174.6 -85.9 91.5 13.3 41.7 -14.9 128 247 A A T 3 S+ 0 0 0 -20,-1.7 -1,-0.2 -2,-1.3 -19,-0.2 0.637 79.2 41.5 -74.9 -17.7 15.0 45.0 -15.0 129 248 A H T 3 S- 0 0 62 -21,-0.6 44,-2.5 1,-0.4 -1,-0.3 0.166 120.1-105.8-109.5 15.0 18.6 43.6 -15.2 130 249 A G E < -F 172 0B 4 -3,-1.6 -1,-0.4 42,-0.3 42,-0.3 -0.285 33.4-108.8 89.4-172.9 17.6 41.0 -17.7 131 250 A T E -F 171 0B 12 40,-1.3 40,-0.6 3,-0.2 3,-0.4 -0.967 11.9-132.0-154.7 155.4 17.0 37.3 -17.4 132 251 A F E S+ 0 0 6 -21,-0.4 40,-0.1 -2,-0.3 -20,-0.1 0.473 92.7 88.9 -88.6 -4.4 18.5 33.9 -18.4 133 252 A A E S+ 0 0 21 13,-0.1 13,-3.1 38,-0.1 14,-0.4 0.638 98.1 25.5 -70.7 -13.3 14.9 32.8 -19.6 134 253 A S E - G 0 145B 36 -3,-0.4 37,-2.7 11,-0.3 2,-0.3 -0.971 67.7-163.3-145.3 164.2 15.7 34.2 -23.0 135 254 A A E -FG 170 144B 0 9,-2.9 9,-3.2 -2,-0.3 2,-0.4 -0.928 5.3-150.1-146.5 164.7 18.8 34.9 -25.2 136 255 A T E -FG 169 143B 30 33,-2.4 33,-2.5 -2,-0.3 2,-0.3 -0.999 25.5-113.3-144.3 131.7 19.7 36.9 -28.3 137 256 A C E > -F 168 0B 0 5,-2.5 4,-1.2 -2,-0.4 31,-0.2 -0.513 23.9-143.2 -61.4 126.6 22.2 36.5 -31.1 138 257 A T T 4 S+ 0 0 32 29,-2.8 -1,-0.1 -2,-0.3 30,-0.1 0.589 94.2 38.3 -71.1 -13.3 24.8 39.3 -30.7 139 258 A V T 4 S+ 0 0 102 28,-0.3 -1,-0.1 3,-0.1 29,-0.0 0.854 130.0 19.0-100.1 -63.0 25.1 39.7 -34.5 140 259 A C T 4 S- 0 0 61 2,-0.1 -2,-0.1 1,-0.0 -3,-0.0 0.559 94.5-125.7 -91.1 -7.8 21.6 39.3 -36.1 141 260 A Q < + 0 0 122 -4,-1.2 -3,-0.1 1,-0.2 27,-0.0 0.650 47.1 165.6 69.5 20.0 19.5 39.9 -33.0 142 261 A R - 0 0 126 -6,-0.1 -5,-2.5 1,-0.1 2,-0.3 -0.472 31.2-133.0 -64.3 128.8 17.6 36.6 -33.3 143 262 A P E -G 136 0B 91 0, 0.0 -7,-0.2 0, 0.0 -1,-0.1 -0.641 24.1-173.3 -87.4 148.4 15.8 35.9 -30.0 144 263 A F E -G 135 0B 22 -9,-3.2 -9,-2.9 -2,-0.3 2,-0.1 -0.992 28.6-113.1-137.1 141.6 15.8 32.5 -28.3 145 264 A P E > -G 134 0B 56 0, 0.0 3,-1.4 0, 0.0 4,-0.4 -0.519 35.6-117.2 -65.7 147.0 14.1 30.9 -25.4 146 265 A G G > S+ 0 0 3 -13,-3.1 3,-1.3 1,-0.3 4,-0.4 0.833 113.3 61.3 -52.9 -37.3 16.6 30.2 -22.6 147 266 A E G > S+ 0 0 131 -14,-0.4 3,-0.7 1,-0.2 4,-0.5 0.779 91.4 67.9 -61.9 -28.6 15.9 26.4 -22.9 148 267 A D G < S+ 0 0 112 -3,-1.4 -1,-0.2 1,-0.3 -2,-0.2 0.660 109.3 34.2 -72.0 -16.6 17.1 26.4 -26.5 149 268 A I G <> S+ 0 0 9 -3,-1.3 4,-2.3 -4,-0.4 -1,-0.3 0.343 89.6 102.5-113.3 3.2 20.7 27.1 -25.4 150 269 A R H <> S+ 0 0 100 -3,-0.7 4,-3.0 -4,-0.4 5,-0.3 0.895 77.8 53.9 -50.8 -50.1 20.5 25.1 -22.1 151 270 A A H > S+ 0 0 68 -4,-0.5 4,-1.3 1,-0.2 -1,-0.2 0.913 111.5 44.8 -55.4 -46.2 22.4 22.1 -23.5 152 271 A D H 4>S+ 0 0 46 2,-0.2 5,-3.1 1,-0.2 -1,-0.2 0.896 113.7 50.1 -64.9 -42.9 25.4 24.2 -24.7 153 272 A V H ><5S+ 0 0 2 -4,-2.3 3,-1.0 1,-0.2 -2,-0.2 0.916 113.1 45.3 -62.7 -45.5 25.4 26.2 -21.4 154 273 A M H 3<5S+ 0 0 65 -4,-3.0 -1,-0.2 1,-0.2 -2,-0.2 0.747 115.8 48.4 -68.6 -23.4 25.4 22.9 -19.3 155 274 A A T 3<5S- 0 0 45 -4,-1.3 -1,-0.2 -5,-0.3 -2,-0.2 0.285 114.9-115.1-100.1 8.4 28.1 21.4 -21.6 156 275 A D T < 5 + 0 0 82 -3,-1.0 2,-0.4 1,-0.2 -3,-0.2 0.746 69.6 137.8 58.7 30.4 30.4 24.6 -21.5 157 276 A R < - 0 0 133 -5,-3.1 -1,-0.2 -6,-0.2 -2,-0.2 -0.871 61.0-120.5 -99.3 137.9 29.9 25.4 -25.2 158 277 A V - 0 0 30 -2,-0.4 11,-0.1 -3,-0.1 -5,-0.1 -0.700 39.4-122.1 -75.0 110.2 29.4 29.0 -26.2 159 278 A P - 0 0 1 0, 0.0 9,-2.3 0, 0.0 2,-0.3 -0.188 30.3-154.0 -63.3 148.1 26.0 28.8 -27.9 160 279 A R B -H 167 0C 136 7,-0.2 7,-0.2 -23,-0.1 6,-0.1 -0.894 20.2-103.4-129.2 154.1 25.8 29.9 -31.5 161 280 A C > - 0 0 4 5,-2.4 4,-2.7 -2,-0.3 5,-0.1 -0.635 19.8-150.6 -78.4 122.0 23.2 31.3 -33.9 162 281 A P T 4 S+ 0 0 107 0, 0.0 -1,-0.2 0, 0.0 0, 0.0 0.882 97.1 45.3 -57.0 -39.3 22.0 28.7 -36.4 163 282 A V T 4 S+ 0 0 107 1,-0.1 -2,-0.0 3,-0.1 -3,-0.0 0.985 134.2 6.2 -68.4 -60.7 21.4 31.5 -38.9 164 283 A C T 4 S- 0 0 48 2,-0.1 -1,-0.1 0, 0.0 -3,-0.0 0.365 88.6-119.2-115.2 2.0 24.5 33.6 -38.7 165 284 A T < + 0 0 92 -4,-2.7 3,-0.1 1,-0.2 -2,-0.0 0.479 62.5 147.8 70.6 3.2 27.0 31.8 -36.4 166 285 A G - 0 0 6 -6,-0.1 -5,-2.4 1,-0.1 -1,-0.2 -0.311 58.9 -93.3 -65.1 152.2 27.0 34.7 -34.0 167 286 A V B -H 160 0C 16 -7,-0.2 -29,-2.8 -30,-0.1 2,-0.7 -0.466 36.9-136.5 -63.0 132.0 27.5 34.2 -30.2 168 287 A V E -F 137 0B 0 -9,-2.3 -31,-0.3 -31,-0.2 -1,-0.1 -0.883 22.8-163.0 -96.3 116.8 24.1 33.9 -28.5 169 288 A K E -F 136 0B 17 -33,-2.5 -33,-2.4 -2,-0.7 -11,-0.0 -0.862 22.1-111.7-106.4 129.4 24.1 35.9 -25.3 170 289 A P E -F 135 0B 0 0, 0.0 2,-1.9 0, 0.0 -35,-0.3 -0.227 40.1-104.2 -49.9 145.2 21.6 35.5 -22.4 171 290 A D E S+F 131 0B 46 -37,-2.7 -40,-1.3 -40,-0.6 2,-0.3 -0.142 72.2 138.9 -78.5 41.8 19.4 38.6 -22.0 172 291 A I E -F 130 0B 4 -2,-1.9 2,-0.5 -42,-0.3 -42,-0.3 -0.713 59.5-116.7 -79.3 135.7 21.2 39.9 -19.0 173 292 A V - 0 0 29 -44,-2.5 2,-0.2 -2,-0.3 3,-0.1 -0.673 32.5-153.4 -78.0 122.1 21.7 43.7 -19.1 174 293 A F > - 0 0 3 -2,-0.5 3,-2.2 1,-0.1 -112,-0.2 -0.579 35.5 -71.5 -92.4 158.4 25.5 44.5 -19.3 175 294 A F T 3 S+ 0 0 105 -114,-2.4 -112,-0.4 1,-0.3 -1,-0.1 -0.203 121.1 15.4 -47.9 130.1 27.1 47.8 -18.1 176 295 A G T 3 S+ 0 0 92 1,-0.3 -1,-0.3 -3,-0.1 -114,-0.1 0.359 98.0 120.7 84.1 -5.5 26.3 50.7 -20.4 177 296 A E S < S- 0 0 71 -3,-2.2 -1,-0.3 1,-0.1 2,-0.2 -0.501 70.5 -97.5 -84.1 160.0 23.4 48.9 -22.1 178 297 A P - 0 0 110 0, 0.0 -4,-0.1 0, 0.0 3,-0.1 -0.502 42.3-104.5 -72.7 147.4 19.7 50.2 -22.1 179 298 A L - 0 0 54 -2,-0.2 -50,-0.1 1,-0.1 -51,-0.1 -0.348 54.7 -80.5 -65.5 152.1 17.3 48.8 -19.6 180 299 A P > - 0 0 41 0, 0.0 3,-1.5 0, 0.0 4,-0.3 -0.104 36.1-114.5 -58.6 157.7 14.9 46.3 -21.2 181 300 A Q G > S+ 0 0 153 1,-0.3 3,-2.2 2,-0.2 4,-0.1 0.877 113.1 65.8 -58.4 -40.3 11.8 47.6 -23.0 182 301 A R G > S+ 0 0 102 1,-0.3 3,-1.6 2,-0.2 -1,-0.3 0.656 83.9 76.1 -56.4 -20.2 9.4 46.1 -20.4 183 302 A F G X S+ 0 0 15 -3,-1.5 3,-1.7 1,-0.3 -1,-0.3 0.791 79.2 71.2 -62.6 -27.7 10.9 48.5 -17.8 184 303 A L G X S+ 0 0 98 -3,-2.2 3,-1.3 -4,-0.3 4,-0.4 0.556 74.2 85.3 -66.7 -8.8 8.8 51.3 -19.5 185 304 A L G <> + 0 0 48 -3,-1.6 4,-2.7 1,-0.2 3,-0.5 0.616 69.8 79.6 -62.6 -14.1 5.8 49.6 -17.9 186 305 A H H <> S+ 0 0 45 -3,-1.7 4,-1.9 1,-0.2 -1,-0.2 0.781 78.9 69.2 -64.6 -26.6 6.6 51.6 -14.8 187 306 A V H <4 S+ 0 0 88 -3,-1.3 -1,-0.2 1,-0.2 -2,-0.2 0.902 114.9 23.3 -60.3 -45.4 4.9 54.6 -16.5 188 307 A V H > S+ 0 0 79 -3,-0.5 4,-1.1 -4,-0.4 -2,-0.2 0.844 120.8 58.4 -87.2 -38.2 1.5 52.9 -16.1 189 308 A D H X S+ 0 0 1 -4,-2.7 4,-1.0 1,-0.2 3,-0.3 0.905 101.5 51.5 -60.5 -48.1 2.1 50.6 -13.2 190 309 A F H >< S+ 0 0 0 -4,-1.9 3,-0.6 1,-0.2 26,-0.4 0.887 109.2 46.8 -68.4 -42.3 3.2 53.1 -10.5 191 310 A P H 34 S+ 0 0 70 0, 0.0 -1,-0.2 0, 0.0 -2,-0.2 0.786 114.7 51.9 -63.2 -24.8 0.3 55.5 -10.8 192 311 A M H 3< S+ 0 0 91 -4,-1.1 -2,-0.2 -3,-0.3 -3,-0.1 0.650 86.8 109.4 -82.8 -19.0 -2.0 52.4 -10.7 193 312 A A << - 0 0 0 -4,-1.0 23,-0.4 -3,-0.6 -172,-0.2 -0.301 40.1-179.3 -64.7 138.4 -0.3 51.0 -7.5 194 313 A D S S+ 0 0 27 -174,-2.3 2,-0.3 1,-0.3 -173,-0.2 0.393 77.9 28.4-115.1 -1.3 -2.3 50.9 -4.3 195 314 A L E -b 21 0A 0 -175,-1.0 -173,-2.7 24,-0.2 2,-0.5 -0.926 67.1-154.0-152.8 134.1 0.5 49.4 -2.3 196 315 A L E -bd 22 221A 0 24,-2.6 26,-3.5 -2,-0.3 2,-0.5 -0.952 12.3-171.1-109.1 119.9 4.3 49.5 -2.7 197 316 A L E -bd 23 222A 0 -175,-2.7 -173,-3.1 -2,-0.5 2,-0.5 -0.947 2.5-173.0-109.6 123.4 6.3 46.5 -1.4 198 317 A I E -bd 24 223A 1 24,-3.4 26,-3.2 -2,-0.5 2,-0.4 -0.969 8.5-174.8-119.0 119.2 10.1 46.8 -1.3 199 318 A L E -bd 25 224A 0 -175,-2.9 -173,-1.6 -2,-0.5 -170,-0.3 -0.959 58.8 -13.9-121.0 127.7 12.0 43.6 -0.3 200 319 A G S S+ 0 0 5 24,-3.0 -172,-2.1 -2,-0.4 -171,-0.4 0.842 113.7 73.0 57.0 42.2 15.7 43.0 0.3 201 320 A T - 0 0 23 23,-0.3 23,-0.1 -175,-0.2 -1,-0.1 -0.902 63.4-147.2-169.0 155.2 17.0 46.3 -1.3 202 321 A S - 0 0 22 -2,-0.3 30,-0.3 -3,-0.1 31,-0.2 0.275 38.6-132.7-109.2 7.3 17.0 50.0 -0.4 203 322 A L + 0 0 1 27,-0.1 9,-0.2 1,-0.1 8,-0.1 0.836 48.7 155.4 45.9 48.4 16.7 51.0 -4.1 204 323 A E + 0 0 97 26,-0.1 2,-0.3 4,-0.1 -1,-0.1 0.695 46.7 73.7 -79.3 -20.6 19.5 53.6 -3.8 205 324 A V S >> S- 0 0 95 4,-0.1 4,-1.3 1,-0.0 3,-0.7 -0.736 88.0 -73.7 -99.1 146.3 20.6 53.6 -7.5 206 325 A E T 34 S+ 0 0 114 -2,-0.3 -2,-0.1 1,-0.3 -1,-0.0 -0.393 106.4 21.4 -72.9 154.0 18.6 55.3 -10.3 207 326 A P T 3> S+ 0 0 49 0, 0.0 4,-1.3 0, 0.0 -1,-0.3 -0.984 125.3 53.4 -85.6 5.2 16.2 54.8 -11.9 208 327 A F H <> S+ 0 0 5 -3,-0.7 4,-0.9 1,-0.2 -2,-0.2 0.842 102.6 61.4 -64.1 -36.3 14.9 52.6 -9.1 209 328 A A H >< S+ 0 0 8 -4,-1.3 3,-0.6 1,-0.2 4,-0.2 0.889 105.5 44.8 -56.3 -46.1 15.4 55.3 -6.5 210 329 A S H >4 S+ 0 0 58 -3,-0.2 3,-2.0 1,-0.2 4,-0.3 0.839 101.2 68.3 -71.5 -34.0 13.0 57.7 -8.2 211 330 A L H >< S+ 0 0 9 -4,-1.3 3,-1.4 1,-0.3 4,-0.4 0.771 85.8 69.2 -55.9 -30.6 10.3 55.0 -8.7 212 331 A T T << S+ 0 0 0 -4,-0.9 -1,-0.3 -3,-0.6 3,-0.2 0.732 104.2 44.3 -61.0 -20.9 9.8 54.8 -4.9 213 332 A E T < S+ 0 0 76 -3,-2.0 -1,-0.3 -4,-0.2 -2,-0.2 0.410 90.8 84.6-103.0 -0.8 8.2 58.3 -5.3 214 333 A A S < S+ 0 0 44 -3,-1.4 2,-0.2 -4,-0.3 -2,-0.2 0.622 72.7 88.9 -76.4 -15.0 6.2 57.5 -8.4 215 334 A V S S- 0 0 4 -4,-0.4 -25,-0.1 -3,-0.2 -21,-0.1 -0.517 92.1 -92.2 -81.7 154.5 3.3 56.1 -6.3 216 335 A R > - 0 0 126 -26,-0.4 3,-1.9 -23,-0.4 -1,-0.1 -0.257 34.5-111.0 -65.9 154.8 0.5 58.4 -5.1 217 336 A S T 3 S+ 0 0 102 1,-0.3 22,-0.3 -3,-0.1 -1,-0.1 0.618 116.1 57.4 -66.1 -14.5 0.9 60.0 -1.6 218 337 A S T 3 S+ 0 0 72 2,-0.1 -1,-0.3 20,-0.1 -2,-0.1 0.583 85.1 103.1 -86.5 -11.5 -2.0 57.9 -0.1 219 338 A V S < S- 0 0 4 -3,-1.9 -24,-0.2 -26,-0.1 20,-0.2 -0.593 72.8-129.1 -79.5 122.2 -0.2 54.6 -1.1 220 339 A P - 0 0 4 0, 0.0 -24,-2.6 0, 0.0 2,-0.5 -0.445 16.3-151.6 -64.2 139.3 1.5 52.8 1.8 221 340 A R E -de 196 240A 0 18,-1.1 20,-2.8 -26,-0.2 2,-0.6 -0.975 8.5-163.3-113.8 117.8 5.2 51.8 1.1 222 341 A L E -de 197 241A 0 -26,-3.5 -24,-3.4 -2,-0.5 2,-0.6 -0.915 1.9-165.8-106.5 120.7 6.3 48.8 3.0 223 342 A L E -de 198 242A 2 18,-2.4 20,-3.4 -2,-0.6 2,-0.6 -0.918 8.9-177.5-104.2 119.1 10.1 48.2 3.3 224 343 A I E +de 199 243A 1 -26,-3.2 -24,-3.0 -2,-0.6 2,-0.3 -0.932 39.5 119.2-113.9 106.2 11.3 44.8 4.4 225 344 A N E S- e 0 244A 20 18,-1.4 20,-0.7 -2,-0.6 -2,-0.1 -0.958 76.3 -98.2-162.0 159.5 15.1 45.2 4.5 226 345 A R S S+ 0 0 171 -2,-0.3 19,-1.0 18,-0.2 2,-0.3 0.924 104.0 15.6 -54.0 -48.1 18.0 45.0 6.9 227 346 A D S S- 0 0 89 17,-0.2 2,-1.1 -3,-0.1 -1,-0.1 -0.869 73.7-115.7-131.1 156.0 18.1 48.8 7.5 228 347 A L S S+ 0 0 84 -2,-0.3 2,-0.3 14,-0.1 -26,-0.1 -0.791 71.0 121.0 -91.3 91.9 16.0 51.9 6.9 229 348 A V + 0 0 56 -2,-1.1 3,-0.4 4,-0.0 4,-0.2 -0.849 35.8 51.2-143.4 174.1 18.2 53.6 4.4 230 349 A G S >> S- 0 0 0 -2,-0.3 4,-2.1 1,-0.2 3,-1.4 -0.301 110.3 -31.4 82.4-175.5 17.9 54.8 0.8 231 350 A P H 3> S+ 0 0 5 0, 0.0 4,-2.9 0, 0.0 -1,-0.2 0.791 134.6 59.9 -47.4 -39.6 15.2 57.1 -0.7 232 351 A L H 34 S+ 0 0 11 -3,-0.4 -2,-0.2 -30,-0.3 5,-0.1 0.854 112.6 38.2 -60.7 -35.8 12.5 55.7 1.8 233 352 A A H <4 S+ 0 0 35 -3,-1.4 -1,-0.2 -4,-0.2 -3,-0.1 0.810 116.7 52.2 -81.8 -30.3 14.6 56.9 4.7 234 353 A W H < S+ 0 0 149 -4,-2.1 -2,-0.2 1,-0.3 -1,-0.1 0.857 126.4 21.5 -71.8 -37.0 15.7 60.1 2.9 235 354 A H S < S- 0 0 99 -4,-2.9 -1,-0.3 -5,-0.2 -2,-0.1 -0.638 83.5-172.5-132.9 73.7 12.1 61.1 2.1 236 355 A P - 0 0 99 0, 0.0 2,-0.3 0, 0.0 -3,-0.1 -0.260 8.2-151.4 -68.7 156.1 9.6 59.4 4.4 237 356 A R > - 0 0 67 -5,-0.1 3,-1.8 -16,-0.1 -16,-0.1 -0.906 27.5-111.7-125.5 155.4 5.9 59.5 3.9 238 357 A S T 3 S+ 0 0 107 -2,-0.3 -234,-0.5 1,-0.3 -20,-0.1 0.758 116.0 50.3 -63.0 -25.1 3.2 59.3 6.6 239 358 A R T 3 S+ 0 0 85 -22,-0.3 -18,-1.1 -20,-0.2 2,-0.3 -0.032 83.4 121.2-105.0 30.1 2.0 55.9 5.4 240 359 A D E < -e 221 0A 28 -3,-1.8 2,-0.4 -20,-0.2 -236,-0.4 -0.710 41.3-167.4 -87.9 144.1 5.4 54.2 5.2 241 360 A V E -e 222 0A 12 -20,-2.8 -18,-2.4 -2,-0.3 2,-0.5 -0.993 4.0-158.5-129.6 138.0 6.1 51.1 7.2 242 361 A A E -e 223 0A 41 -2,-0.4 2,-0.6 -20,-0.2 -18,-0.2 -0.980 8.1-171.8-116.3 126.6 9.5 49.6 7.9 243 362 A Q E -e 224 0A 42 -20,-3.4 -18,-1.4 -2,-0.5 2,-0.2 -0.932 25.2-168.9-112.8 105.0 10.1 46.0 8.8 244 363 A L E +e 225 0A 81 -2,-0.6 2,-0.4 -20,-0.2 -18,-0.2 -0.493 38.5 35.3-100.7 160.1 13.8 45.8 9.7 245 364 A G S S+ 0 0 31 -19,-1.0 2,-0.4 -20,-0.7 -2,-0.1 -0.859 103.7 15.7 107.6-137.8 16.2 42.9 10.3 246 365 A D > - 0 0 86 -2,-0.4 4,-2.4 1,-0.1 5,-0.2 -0.628 60.4-146.7 -82.9 125.4 16.1 39.6 8.6 247 366 A V H > S+ 0 0 12 -2,-0.4 4,-2.8 1,-0.2 5,-0.2 0.871 97.7 55.6 -58.1 -40.7 14.0 39.5 5.4 248 367 A V H > S+ 0 0 28 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.928 111.3 43.4 -60.3 -48.9 12.9 35.9 5.9 249 368 A H H > S+ 0 0 105 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.874 113.8 51.6 -61.0 -42.8 11.5 36.7 9.4 250 369 A G H X S+ 0 0 1 -4,-2.4 4,-1.9 2,-0.2 -2,-0.2 0.902 113.1 44.8 -61.4 -43.4 9.9 39.9 8.2 251 370 A V H X S+ 0 0 0 -4,-2.8 4,-2.8 2,-0.2 -2,-0.2 0.932 113.7 49.4 -66.8 -45.7 8.2 38.0 5.3 252 371 A E H X S+ 0 0 100 -4,-2.6 4,-2.1 1,-0.2 -2,-0.2 0.841 109.4 52.8 -65.5 -34.2 7.1 35.2 7.6 253 372 A S H X S+ 0 0 35 -4,-2.4 4,-2.4 2,-0.2 -1,-0.2 0.916 111.5 46.0 -64.2 -44.2 5.7 37.7 10.1 254 373 A L H X S+ 0 0 0 -4,-1.9 4,-2.1 2,-0.2 -2,-0.2 0.926 110.2 54.0 -62.8 -45.2 3.7 39.3 7.4 255 374 A V H X>S+ 0 0 5 -4,-2.8 5,-2.6 2,-0.2 4,-1.0 0.912 110.7 46.8 -55.0 -45.3 2.5 35.9 6.1 256 375 A E H ><5S+ 0 0 124 -4,-2.1 3,-1.0 1,-0.2 -2,-0.2 0.943 111.0 50.1 -63.1 -49.6 1.2 35.0 9.6 257 376 A L H 3<5S+ 0 0 68 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.802 111.0 51.5 -60.3 -29.5 -0.5 38.3 10.1 258 377 A L H 3<5S- 0 0 0 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.704 113.9-120.1 -75.5 -23.7 -2.2 37.8 6.7 259 378 A G T <<5S+ 0 0 51 -3,-1.0 4,-0.2 -4,-1.0 -3,-0.2 0.674 79.8 118.8 87.4 22.9 -3.4 34.3 7.7 260 379 A W >< + 0 0 19 -5,-2.6 4,-3.2 -6,-0.2 5,-0.2 0.321 32.2 106.4-103.3 6.6 -1.4 32.5 4.9 261 380 A T H > S+ 0 0 60 -6,-0.4 4,-2.4 1,-0.2 5,-0.2 0.910 85.9 40.3 -55.2 -51.2 0.9 30.3 7.0 262 381 A E H > S+ 0 0 158 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.873 116.8 51.0 -65.9 -38.6 -0.8 27.0 6.3 263 382 A E H > S+ 0 0 85 -4,-0.2 4,-2.2 2,-0.2 -2,-0.2 0.891 110.3 49.8 -64.6 -40.4 -1.4 28.0 2.7 264 383 A M H X S+ 0 0 10 -4,-3.2 4,-3.0 2,-0.2 5,-0.2 0.934 109.5 50.7 -60.3 -52.5 2.4 28.9 2.4 265 384 A R H X S+ 0 0 183 -4,-2.4 4,-2.1 1,-0.2 -2,-0.2 0.872 111.8 47.6 -54.3 -43.7 3.5 25.5 3.8 266 385 A D H X S+ 0 0 73 -4,-2.0 4,-2.6 2,-0.2 -1,-0.2 0.916 113.1 48.1 -66.6 -44.0 1.2 23.6 1.4 267 386 A L H X S+ 0 0 2 -4,-2.2 4,-2.9 2,-0.2 -2,-0.2 0.941 112.9 47.6 -59.7 -50.8 2.5 25.7 -1.6 268 387 A V H X S+ 0 0 46 -4,-3.0 4,-2.5 2,-0.2 -2,-0.2 0.885 112.1 51.3 -57.9 -42.7 6.1 25.2 -0.6 269 388 A Q H X S+ 0 0 132 -4,-2.1 4,-1.4 -5,-0.2 -2,-0.2 0.975 113.4 43.4 -56.3 -59.9 5.5 21.4 -0.1 270 389 A R H < S+ 0 0 149 -4,-2.6 3,-0.2 1,-0.2 -2,-0.2 0.900 115.9 48.0 -51.9 -48.8 3.9 21.0 -3.5 271 390 A E H < S+ 0 0 23 -4,-2.9 3,-0.4 1,-0.2 -1,-0.2 0.861 104.1 57.8 -68.9 -39.7 6.5 23.2 -5.3 272 391 A T H < S+ 0 0 104 -4,-2.5 2,-1.6 1,-0.3 -1,-0.2 0.857 95.3 69.7 -57.2 -36.3 9.6 21.5 -3.8 273 392 A G < 0 0 67 -4,-1.4 -1,-0.3 -3,-0.2 -2,-0.1 -0.272 360.0 360.0 -77.9 49.8 8.2 18.2 -5.3 274 393 A K 0 0 181 -2,-1.6 -3,-0.0 -3,-0.4 0, 0.0 -0.964 360.0 360.0-148.6 360.0 9.0 19.5 -8.8