==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=2-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 16-APR-08 2K31 . COMPND 2 MOLECULE: PHOSPHODIESTERASE 5A, CGMP-SPECIFIC; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR C.C.HEIKAUS,J.R.STOUT,M.R.SEKHARAN,C.M.EAKIN,P.RAJAGOPAL, . 149 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9820.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 86 57.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 36 24.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 7 4.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 31 20.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 2 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 154 A D 0 0 167 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 148.0 -17.7 8.5 -10.4 2 155 A V + 0 0 124 3,-0.1 4,-0.3 2,-0.1 0, 0.0 0.522 360.0 46.3-116.4 -16.0 -14.6 6.3 -10.8 3 156 A T S S+ 0 0 88 2,-0.1 4,-0.4 3,-0.1 0, 0.0 0.802 115.7 42.4 -95.4 -38.3 -12.3 7.9 -8.2 4 157 A A S >> S+ 0 0 33 1,-0.2 3,-0.9 2,-0.2 4,-0.8 0.837 108.9 58.7 -77.2 -35.9 -14.8 8.2 -5.3 5 158 A L H 3> S+ 0 0 102 1,-0.2 4,-0.7 2,-0.2 3,-0.4 0.814 98.9 59.5 -63.3 -33.3 -16.3 4.7 -5.8 6 159 A C H 3> S+ 0 0 43 -4,-0.3 4,-0.6 1,-0.2 -1,-0.2 0.739 101.2 55.7 -66.8 -24.6 -12.8 3.1 -5.3 7 160 A H H <> S+ 0 0 8 -3,-0.9 4,-0.7 -4,-0.4 -1,-0.2 0.766 95.5 66.5 -77.1 -28.6 -12.8 4.7 -1.8 8 161 A K H X S+ 0 0 119 -4,-0.8 4,-0.6 -3,-0.4 3,-0.4 0.824 100.7 48.4 -61.5 -35.6 -16.1 3.0 -0.9 9 162 A I H X S+ 0 0 38 -4,-0.7 4,-0.9 1,-0.2 3,-0.3 0.768 102.7 64.2 -75.3 -28.7 -14.4 -0.5 -1.0 10 163 A F H X S+ 0 0 14 -4,-0.6 4,-0.6 1,-0.2 -1,-0.2 0.709 97.9 54.6 -67.6 -25.3 -11.5 0.8 1.2 11 164 A L H < S+ 0 0 60 -4,-0.7 4,-0.5 -3,-0.4 -1,-0.2 0.785 101.6 57.7 -80.2 -29.3 -13.9 1.4 4.1 12 165 A H H < S+ 0 0 128 -4,-0.6 3,-0.4 -3,-0.3 4,-0.3 0.806 105.7 49.6 -70.1 -32.0 -15.2 -2.2 4.1 13 166 A I H X S+ 0 0 8 -4,-0.9 4,-2.1 1,-0.2 5,-0.4 0.738 98.6 67.3 -78.2 -25.8 -11.6 -3.6 4.6 14 167 A H T <>S+ 0 0 16 -4,-0.6 5,-1.1 1,-0.2 -1,-0.2 0.720 112.9 32.6 -65.9 -22.7 -11.0 -1.2 7.5 15 168 A G T 45S+ 0 0 68 -4,-0.5 -1,-0.2 -3,-0.4 -2,-0.2 0.397 118.1 55.0-113.0 -2.6 -13.6 -3.2 9.5 16 169 A L T 45S+ 0 0 92 -4,-0.3 -2,-0.2 -3,-0.3 -3,-0.2 0.874 125.1 17.3 -95.0 -52.6 -13.0 -6.6 7.9 17 170 A I T <5S- 0 0 22 -4,-2.1 -3,-0.1 122,-0.1 -2,-0.1 0.335 107.5-120.9-101.8 3.8 -9.3 -7.2 8.5 18 171 A S T 5 + 0 0 67 -5,-0.4 2,-0.2 1,-0.1 -3,-0.2 0.941 47.5 166.5 51.4 98.9 -9.1 -4.4 11.2 19 172 A A < - 0 0 13 -5,-1.1 104,-0.1 1,-0.1 -1,-0.1 -0.815 39.0-143.6-133.9 173.1 -6.5 -1.8 10.1 20 173 A D S S+ 0 0 83 1,-0.4 2,-0.3 102,-0.4 103,-0.2 0.836 78.4 0.3-104.0 -56.8 -5.4 1.8 11.0 21 174 A R E -A 122 0A 92 101,-1.5 101,-0.8 24,-0.1 -1,-0.4 -0.980 56.9-155.7-139.9 151.0 -4.5 3.5 7.6 22 175 A Y E -AB 121 44A 7 22,-0.6 22,-0.7 -2,-0.3 2,-0.3 -0.950 11.4-179.1-126.7 146.3 -4.4 2.6 3.9 23 176 A S E -A 120 0A 11 97,-1.6 97,-1.7 -2,-0.3 2,-0.4 -0.992 12.1-156.4-144.3 149.6 -2.4 4.0 1.0 24 177 A L E -AB 119 41A 29 17,-1.1 16,-1.2 -2,-0.3 17,-0.7 -0.971 8.6-168.3-133.9 120.1 -2.1 3.4 -2.8 25 178 A F E -AB 118 39A 12 93,-2.6 93,-3.0 -2,-0.4 2,-0.3 -0.784 11.1-144.1-105.0 147.2 0.9 4.2 -4.9 26 179 A L E -AB 117 38A 76 12,-1.5 12,-1.3 -2,-0.3 2,-0.5 -0.808 24.3-104.2-110.6 153.2 1.0 4.2 -8.7 27 180 A V E + B 0 37A 43 89,-2.9 2,-0.4 -2,-0.3 10,-0.2 -0.644 42.4 175.1 -80.1 121.7 3.8 3.2 -11.1 28 181 A C E + B 0 36A 41 8,-1.8 8,-3.4 -2,-0.5 2,-0.3 -0.997 2.1 170.1-132.1 131.4 5.7 6.1 -12.6 29 182 A E E - B 0 35A 132 -2,-0.4 6,-0.3 6,-0.3 2,-0.2 -0.962 19.9-139.7-138.5 154.2 8.8 6.0 -14.9 30 183 A D E >> - B 0 34A 91 4,-3.0 3,-0.9 -2,-0.3 4,-0.9 -0.730 25.6-119.4-111.7 161.8 10.8 8.4 -17.0 31 184 A S T 34 S+ 0 0 128 1,-0.3 -1,-0.0 -2,-0.2 -2,-0.0 0.543 107.3 74.4 -75.2 -7.8 12.4 8.0 -20.5 32 185 A S T 34 S- 0 0 98 2,-0.2 -1,-0.3 1,-0.0 0, 0.0 0.139 123.2 -96.0 -91.0 19.2 15.8 8.8 -18.8 33 186 A K T <4 S+ 0 0 199 -3,-0.9 2,-0.3 1,-0.2 -2,-0.2 0.993 85.3 125.3 61.8 65.7 15.8 5.3 -17.2 34 187 A D E < -B 30 0A 104 -4,-0.9 -4,-3.0 2,-0.0 2,-0.4 -0.920 36.9-170.1-155.2 123.5 14.4 6.3 -13.8 35 188 A K E +B 29 0A 79 -2,-0.3 27,-1.2 -6,-0.3 2,-0.3 -0.936 10.8 170.1-121.8 143.2 11.4 4.8 -12.0 36 189 A F E -BC 28 61A 69 -8,-3.4 -8,-1.8 -2,-0.4 2,-0.4 -0.947 28.2-121.5-147.0 163.4 9.6 6.1 -8.9 37 190 A L E +BC 27 60A 1 23,-3.6 23,-2.2 -2,-0.3 2,-0.4 -0.928 24.5 177.0-112.8 132.5 6.5 5.6 -6.7 38 191 A I E -BC 26 59A 31 -12,-1.3 -12,-1.5 -2,-0.4 2,-0.3 -0.934 20.1-143.1-139.9 113.1 4.0 8.3 -6.0 39 192 A S E -B 25 0A 0 19,-2.1 -14,-0.2 -2,-0.4 19,-0.1 -0.586 7.8-166.7 -76.5 130.9 0.8 7.8 -4.0 40 193 A R E S+ 0 0 138 -16,-1.2 2,-0.4 -2,-0.3 -1,-0.1 0.913 78.7 44.3 -81.0 -49.5 -2.3 9.7 -5.1 41 194 A L E S-B 24 0A 20 -17,-0.7 -17,-1.1 16,-0.0 2,-0.4 -0.856 74.0-168.1-101.0 133.2 -4.4 9.1 -2.0 42 195 A F E + 0 0 22 11,-2.7 13,-0.2 -2,-0.4 -19,-0.1 -0.974 55.5 2.3-126.8 135.6 -2.8 9.5 1.4 43 196 A D E - 0 0 60 -2,-0.4 2,-0.4 -21,-0.2 -1,-0.3 0.944 67.2-162.8 55.3 98.9 -4.1 8.4 4.9 44 197 A V E +B 22 0A 1 -22,-0.7 -22,-0.6 -3,-0.1 2,-0.3 -0.947 11.0 177.6-114.0 130.6 -7.5 6.7 4.6 45 198 A A > - 0 0 28 -2,-0.4 2,-1.0 -24,-0.1 3,-1.0 -0.843 42.1 -85.4-128.2 164.5 -9.8 6.2 7.6 46 199 A E T 3 S+ 0 0 135 -2,-0.3 -35,-0.0 1,-0.3 -34,-0.0 -0.589 117.2 18.0 -74.5 101.4 -13.3 4.8 8.2 47 200 A G T 3 S+ 0 0 71 -2,-1.0 2,-0.3 1,-0.3 -1,-0.3 0.766 95.5 127.8 105.9 39.3 -15.7 7.6 7.4 48 201 A S < - 0 0 34 -3,-1.0 -1,-0.3 -41,-0.1 2,-0.1 -0.904 49.1-128.7-125.8 153.6 -13.4 10.0 5.3 49 202 A T - 0 0 86 -2,-0.3 3,-0.4 1,-0.1 4,-0.4 -0.435 25.3-113.1 -94.4 170.3 -13.8 11.6 1.9 50 203 A L S >> S+ 0 0 39 1,-0.2 4,-1.3 2,-0.2 3,-1.1 0.830 113.2 65.1 -71.1 -34.8 -11.4 11.7 -1.1 51 204 A E T 34 S+ 0 0 153 1,-0.3 4,-0.3 2,-0.2 -1,-0.2 0.791 103.2 48.1 -57.6 -31.1 -10.8 15.5 -0.7 52 205 A E T 34 S+ 0 0 145 -3,-0.4 -1,-0.3 1,-0.2 -2,-0.2 0.602 115.2 45.3 -84.1 -15.0 -9.2 14.7 2.7 53 206 A A T <4 S+ 0 0 1 -3,-1.1 -11,-2.7 -4,-0.4 -2,-0.2 0.475 103.6 63.1-104.3 -8.2 -7.1 11.9 1.0 54 207 A S S < S+ 0 0 74 -4,-1.3 2,-0.4 -13,-0.2 -2,-0.1 0.568 86.1 88.8 -91.9 -12.4 -6.0 14.0 -2.0 55 208 A N S S+ 0 0 108 -4,-0.3 -13,-0.2 -5,-0.2 -15,-0.0 -0.745 91.2 5.5 -92.4 134.4 -4.1 16.5 0.1 56 209 A N S S- 0 0 112 -2,-0.4 2,-0.3 1,-0.1 -1,-0.1 0.873 75.1-160.6 60.1 110.3 -0.4 15.9 0.9 57 210 A C - 0 0 38 -3,-0.1 2,-0.4 -16,-0.1 -17,-0.1 -0.853 12.6-124.4-121.0 156.2 1.1 12.8 -0.9 58 211 A I - 0 0 8 -2,-0.3 -19,-2.1 -19,-0.1 2,-0.5 -0.811 15.5-156.4-102.0 139.8 4.1 10.6 -0.3 59 212 A R E +C 38 0A 172 -2,-0.4 2,-0.3 -21,-0.2 -21,-0.2 -0.965 16.2 177.2-119.3 116.6 6.8 10.0 -2.9 60 213 A L E -C 37 0A 16 -23,-2.2 -23,-3.6 -2,-0.5 2,-0.1 -0.825 28.5-107.9-117.5 157.2 9.0 6.8 -2.6 61 214 A E E >> -C 36 0A 80 -2,-0.3 3,-0.7 -25,-0.2 4,-0.6 -0.337 37.4 -99.2 -78.8 162.0 11.7 5.4 -4.9 62 215 A W T 34 S- 0 0 43 -27,-1.2 -27,-0.1 1,-0.3 6,-0.1 -0.711 103.4 -1.8 -85.9 130.1 11.4 2.3 -7.1 63 216 A N T 34 S+ 0 0 94 -2,-0.4 -1,-0.3 1,-0.1 6,-0.1 0.892 113.0 99.3 56.3 44.3 12.8 -1.0 -5.6 64 217 A K T <4 S+ 0 0 113 -3,-0.7 -2,-0.1 23,-0.1 -1,-0.1 0.704 74.2 33.4-121.4 -57.3 13.9 1.0 -2.6 65 218 A G S X S- 0 0 9 -4,-0.6 4,-0.5 23,-0.1 23,-0.2 0.091 102.8 -76.5 -88.3-157.9 11.5 0.6 0.3 66 219 A I H > S+ 0 0 24 1,-0.2 4,-0.7 2,-0.2 3,-0.4 0.809 133.3 48.5 -73.3 -32.1 9.3 -2.4 1.4 67 220 A V H > S+ 0 0 7 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.681 99.8 69.0 -79.7 -20.3 6.8 -1.7 -1.4 68 221 A G H > S+ 0 0 0 2,-0.2 4,-0.9 1,-0.2 -1,-0.2 0.745 95.9 53.2 -69.5 -25.7 9.7 -1.5 -3.9 69 222 A H H X S+ 0 0 72 -4,-0.5 4,-1.1 -3,-0.4 5,-0.2 0.868 116.0 38.2 -75.5 -40.3 10.4 -5.3 -3.5 70 223 A V H X S+ 0 0 4 -4,-0.7 4,-1.8 2,-0.2 5,-0.4 0.760 113.2 58.2 -78.5 -29.6 6.8 -6.2 -4.3 71 224 A A H < S+ 0 0 6 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.759 105.6 50.8 -69.9 -28.2 6.6 -3.4 -7.0 72 225 A A H < S+ 0 0 48 -4,-0.9 -2,-0.2 -5,-0.1 -1,-0.2 0.862 126.7 20.6 -78.6 -40.4 9.6 -5.0 -8.8 73 226 A F H < S- 0 0 147 -4,-1.1 -2,-0.2 2,-0.1 -3,-0.2 0.882 95.7-130.6 -94.9 -52.3 8.2 -8.6 -9.0 74 227 A G < + 0 0 9 -4,-1.8 -3,-0.1 1,-0.3 -4,-0.1 0.865 57.9 121.3 98.7 52.0 4.4 -8.1 -8.5 75 228 A E - 0 0 127 -5,-0.4 2,-0.6 30,-0.0 -1,-0.3 -0.964 68.7 -93.7-141.4 155.9 3.4 -10.6 -5.7 76 229 A P + 0 0 62 0, 0.0 2,-0.3 0, 0.0 30,-0.2 -0.610 52.0 172.7 -74.9 113.8 1.8 -10.5 -2.2 77 230 A L E -D 105 0A 75 28,-3.2 28,-2.1 -2,-0.6 2,-0.4 -0.839 24.8-128.4-121.0 159.1 4.6 -10.3 0.4 78 231 A N E -D 104 0A 56 -2,-0.3 2,-0.4 26,-0.2 26,-0.2 -0.863 11.6-157.8-112.1 143.0 4.6 -9.8 4.2 79 232 A I E -D 103 0A 22 24,-1.9 24,-1.8 -2,-0.4 3,-0.2 -0.982 9.6-166.9-121.6 126.3 6.7 -7.4 6.3 80 233 A K S S- 0 0 145 -2,-0.4 2,-0.1 1,-0.3 -1,-0.1 0.714 86.0 -6.4 -79.9 -24.8 7.4 -7.9 10.0 81 234 A D + 0 0 46 22,-0.1 -1,-0.3 21,-0.1 20,-0.1 -0.552 58.5 179.3-175.2 102.9 8.6 -4.3 10.5 82 235 A A S > S+ 0 0 8 -3,-0.2 3,-2.4 1,-0.2 5,-0.1 0.984 85.6 48.4 -71.4 -61.0 9.1 -1.7 7.7 83 236 A Y T 3 S+ 0 0 24 1,-0.3 -1,-0.2 17,-0.2 5,-0.1 0.586 119.9 42.1 -59.1 -11.9 10.3 1.4 9.7 84 237 A E T 3 S+ 0 0 147 16,-0.2 -1,-0.3 3,-0.1 -2,-0.2 0.162 94.7 104.3-120.6 15.8 12.8 -0.8 11.5 85 238 A D S < S- 0 0 42 -3,-2.4 3,-0.4 1,-0.1 -3,-0.0 -0.648 76.6-123.2 -97.8 154.4 14.0 -2.9 8.4 86 239 A P S S+ 0 0 120 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 0.684 108.7 53.0 -68.4 -17.6 17.4 -2.4 6.5 87 240 A R S S+ 0 0 158 -5,-0.1 2,-0.3 2,-0.1 -3,-0.1 -0.635 86.7 110.1-119.7 70.6 15.4 -1.9 3.3 88 241 A F - 0 0 64 -2,-0.4 2,-0.6 -3,-0.4 -23,-0.1 -0.945 65.8-114.2-139.6 160.8 13.0 0.9 4.1 89 242 A N - 0 0 29 -2,-0.3 3,-0.5 1,-0.1 4,-0.4 -0.880 19.4-171.5-100.6 117.6 12.4 4.6 3.2 90 243 A A S S+ 0 0 57 -2,-0.6 4,-0.4 1,-0.2 -1,-0.1 0.315 70.8 84.6 -89.9 7.6 12.8 7.0 6.3 91 244 A E S > S+ 0 0 88 2,-0.2 4,-0.7 1,-0.2 3,-0.2 0.799 89.8 48.7 -79.2 -30.1 11.4 10.0 4.4 92 245 A V H > S+ 0 0 19 -3,-0.5 4,-3.1 1,-0.2 3,-0.5 0.850 102.4 62.6 -75.8 -35.6 7.7 9.2 5.1 93 246 A D H > S+ 0 0 30 -4,-0.4 4,-1.3 1,-0.2 -1,-0.2 0.723 97.3 60.9 -60.7 -23.6 8.5 8.6 8.8 94 247 A Q H 4 S+ 0 0 164 -4,-0.4 -1,-0.2 -3,-0.2 -2,-0.2 0.908 116.4 27.7 -70.2 -45.4 9.5 12.3 9.0 95 248 A I H < S+ 0 0 100 -4,-0.7 -2,-0.2 -3,-0.5 -1,-0.1 0.786 127.3 44.0 -87.2 -32.7 6.0 13.6 7.9 96 249 A T H < S- 0 0 43 -4,-3.1 -3,-0.2 2,-0.1 -2,-0.2 0.743 80.6-161.0 -85.6 -24.7 3.9 10.7 9.3 97 250 A G < + 0 0 69 -4,-1.3 2,-0.4 -5,-0.3 -4,-0.1 0.776 48.5 126.1 46.3 33.2 5.8 10.4 12.6 98 251 A Y - 0 0 63 -6,-0.1 2,-0.5 -5,-0.0 -1,-0.2 -0.965 48.5-157.4-125.9 138.1 4.3 6.9 13.0 99 252 A K - 0 0 120 -2,-0.4 2,-0.3 -3,-0.1 25,-0.0 -0.961 13.4-153.3-117.9 115.6 6.1 3.6 13.6 100 253 A T - 0 0 11 -2,-0.5 -17,-0.2 1,-0.1 -16,-0.2 -0.633 13.0-156.3 -89.1 145.2 4.2 0.4 12.5 101 254 A Q S S+ 0 0 88 1,-0.3 2,-0.3 -2,-0.3 23,-0.1 0.722 83.4 9.8 -87.8 -27.3 4.8 -3.0 14.1 102 255 A S - 0 0 17 21,-0.2 21,-1.3 -21,-0.1 2,-0.3 -0.971 63.6-173.3-155.2 139.7 3.6 -4.9 11.0 103 256 A I E -DE 79 122A 1 -24,-1.8 -24,-1.9 -2,-0.3 2,-0.5 -0.999 19.5-135.1-138.5 139.6 2.7 -4.0 7.4 104 257 A L E -DE 78 121A 1 17,-1.2 17,-0.9 -2,-0.3 2,-0.7 -0.826 15.3-153.6 -95.8 124.2 1.3 -6.1 4.5 105 258 A C E +DE 77 120A 0 -28,-2.1 -28,-3.2 -2,-0.5 15,-0.2 -0.876 28.5 153.6-102.8 110.2 2.9 -5.7 1.1 106 259 A M E - E 0 119A 6 13,-2.1 13,-2.4 -2,-0.7 2,-0.1 -0.969 32.7-136.9-139.9 121.4 0.6 -6.4 -1.8 107 260 A P E - E 0 118A 11 0, 0.0 2,-0.6 0, 0.0 11,-0.3 -0.386 15.4-127.4 -77.4 154.2 0.9 -5.0 -5.4 108 261 A I E + E 0 117A 22 9,-2.6 9,-2.5 -83,-0.2 8,-2.4 -0.907 39.5 159.3-105.3 116.4 -2.1 -3.6 -7.4 109 262 A K E - 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0 0 8 -21,-1.3 2,-0.6 -2,-0.6 -21,-0.2 -0.937 32.3-138.9-141.3 112.4 -1.7 -1.2 11.3 124 277 A K + 0 0 110 -2,-0.4 2,-0.3 -23,-0.1 -24,-0.1 -0.606 35.9 164.2 -74.0 113.9 0.0 -1.5 14.7 125 278 A K - 0 0 116 -2,-0.6 2,-0.3 2,-0.1 -2,-0.1 -0.970 30.3-131.5-133.8 148.8 -1.1 -4.7 16.4 126 279 A S + 0 0 109 -2,-0.3 2,-0.2 2,-0.0 -2,-0.0 -0.775 42.2 126.3-101.5 144.2 0.2 -6.8 19.3 127 280 A G - 0 0 62 -2,-0.3 2,-0.4 2,-0.1 -2,-0.1 -0.859 45.7-118.8 172.9 152.8 0.8 -10.6 19.2 128 281 A N S S+ 0 0 174 -2,-0.2 2,-0.6 3,-0.0 -2,-0.0 -0.860 79.2 19.1-109.0 141.2 3.3 -13.4 19.8 129 282 A G S S+ 0 0 83 -2,-0.4 2,-0.1 0, 0.0 -2,-0.1 -0.913 110.3 11.4 113.8-108.6 4.5 -15.8 17.2 130 283 A G - 0 0 70 -2,-0.6 3,-0.1 1,-0.1 0, 0.0 -0.280 61.7-125.3 -98.5-174.2 4.1 -14.8 13.6 131 284 A T S S- 0 0 50 1,-0.4 2,-0.3 -2,-0.1 -1,-0.1 0.877 81.5 -4.6 -97.0 -57.1 3.1 -11.6 11.8 132 285 A F - 0 0 59 -54,-0.0 -1,-0.4 5,-0.0 2,-0.2 -0.908 65.4-119.4-138.1 164.5 0.1 -12.6 9.6 133 286 A T > - 0 0 87 -2,-0.3 4,-0.6 -3,-0.1 3,-0.2 -0.542 25.6-116.4-100.6 168.0 -1.9 -15.6 8.6 134 287 A E H > S+ 0 0 142 1,-0.2 4,-0.5 -2,-0.2 -1,-0.1 0.718 114.5 56.7 -75.3 -22.9 -2.5 -17.2 5.1 135 288 A K H > S+ 0 0 170 1,-0.2 4,-0.6 2,-0.2 -1,-0.2 0.742 102.6 54.4 -79.6 -26.0 -6.2 -16.5 5.3 136 289 A D H 4 S+ 0 0 51 1,-0.2 4,-0.4 -3,-0.2 -1,-0.2 0.704 101.0 59.8 -79.5 -22.9 -5.6 -12.7 5.8 137 290 A E H X S+ 0 0 43 -4,-0.6 4,-1.2 1,-0.2 -1,-0.2 0.744 101.3 54.0 -76.7 -25.9 -3.5 -12.5 2.7 138 291 A K H X S+ 0 0 117 -4,-0.5 4,-1.1 1,-0.2 -1,-0.2 0.741 102.2 57.6 -79.4 -25.6 -6.4 -13.7 0.4 139 292 A D H < S+ 0 0 57 -4,-0.6 4,-0.5 2,-0.2 -1,-0.2 0.657 106.9 49.9 -78.1 -17.7 -8.8 -10.9 1.8 140 293 A F H > S+ 0 0 9 -4,-0.4 4,-1.0 -3,-0.2 -2,-0.2 0.875 112.9 41.6 -87.0 -43.9 -6.3 -8.2 0.7 141 294 A A H X S+ 0 0 42 -4,-1.2 4,-1.1 1,-0.2 -2,-0.2 0.734 110.9 57.5 -77.1 -25.0 -5.7 -9.3 -3.0 142 295 A E H X S+ 0 0 115 -4,-1.1 4,-0.7 2,-0.2 -1,-0.2 0.819 107.0 48.1 -74.6 -32.6 -9.4 -10.2 -3.6 143 296 A Y H > S+ 0 0 71 -4,-0.5 4,-1.3 1,-0.2 -2,-0.2 0.805 112.8 47.7 -76.5 -32.4 -10.5 -6.6 -2.7 144 297 A L H X S+ 0 0 18 -4,-1.0 4,-3.0 2,-0.2 -2,-0.2 0.733 99.5 69.0 -79.3 -26.4 -7.8 -5.0 -5.0 145 298 A A H < S+ 0 0 33 -4,-1.1 4,-0.3 2,-0.2 -34,-0.2 0.868 109.4 34.1 -59.4 -39.8 -8.7 -7.3 -7.9 146 299 A F H < S+ 0 0 174 -4,-0.7 3,-0.5 2,-0.1 -2,-0.2 0.871 126.1 40.1 -82.5 -42.4 -12.1 -5.6 -8.4 147 300 A C H < S+ 0 0 27 -4,-1.3 -2,-0.2 1,-0.2 -3,-0.2 0.744 99.7 77.3 -77.1 -26.9 -11.0 -2.0 -7.4 148 301 A G < 0 0 15 -4,-3.0 -1,-0.2 1,-0.2 -3,-0.1 0.769 360.0 360.0 -54.1 -31.5 -7.7 -2.4 -9.2 149 302 A E 0 0 172 -3,-0.5 -2,-0.2 -4,-0.3 -1,-0.2 0.957 360.0 360.0 -85.2 360.0 -9.4 -1.8 -12.6