==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=22-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 06-OCT-09 3K4S . COMPND 2 MOLECULE: CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.CRAWLEY,R.K.Y.CHENG,M.WOOD,J.BARKER,B.FELICETTI, . 329 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16146.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 238 72.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 9 2.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 14.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 169 51.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 2 1 0 0 0 2 1 4 0 1 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 84 A H 0 0 236 0, 0.0 2,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 130.8 46.6 21.4 -4.7 2 85 A M - 0 0 119 1,-0.1 2,-0.2 2,-0.1 0, 0.0 -0.193 360.0-116.4 -74.4 165.2 44.0 19.0 -6.0 3 86 A T >> - 0 0 78 1,-0.1 4,-1.9 -2,-0.0 3,-1.0 -0.530 32.2-105.6 -94.0 156.9 40.9 19.7 -8.1 4 87 A E T 34 S+ 0 0 145 1,-0.2 7,-0.2 2,-0.2 -1,-0.1 0.895 123.2 53.3 -48.6 -43.0 37.2 19.0 -6.9 5 88 A Q T 34 S+ 0 0 172 1,-0.2 -1,-0.2 6,-0.0 3,-0.0 0.734 111.4 46.7 -64.9 -28.8 37.2 15.9 -9.2 6 89 A E T <4 S+ 0 0 110 -3,-1.0 2,-2.0 1,-0.1 -1,-0.2 0.777 90.8 79.5 -83.1 -33.8 40.4 14.6 -7.6 7 90 A D X + 0 0 70 -4,-1.9 4,-1.7 1,-0.2 -1,-0.1 -0.584 55.2 168.5 -81.8 80.3 39.5 15.0 -3.9 8 91 A V H > + 0 0 74 -2,-2.0 4,-1.9 2,-0.2 -1,-0.2 0.759 69.3 58.3 -70.6 -23.3 37.4 11.9 -3.7 9 92 A L H > S+ 0 0 37 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.974 106.9 45.2 -72.9 -50.4 37.3 12.0 0.1 10 93 A A H > S+ 0 0 41 1,-0.2 4,-0.9 2,-0.2 -2,-0.2 0.893 111.3 56.3 -56.7 -37.8 35.7 15.5 0.3 11 94 A K H >< S+ 0 0 71 -4,-1.7 3,-0.7 1,-0.2 -1,-0.2 0.914 108.9 43.9 -60.9 -47.2 33.3 14.4 -2.4 12 95 A E H >< S+ 0 0 32 -4,-1.9 3,-2.4 1,-0.2 -2,-0.2 0.905 106.4 62.4 -64.1 -40.2 32.1 11.4 -0.4 13 96 A L H >< S+ 0 0 24 -4,-2.5 3,-1.4 1,-0.3 -1,-0.2 0.664 86.6 73.3 -63.0 -18.5 31.9 13.6 2.7 14 97 A E T << S+ 0 0 124 -4,-0.9 3,-0.4 -3,-0.7 -1,-0.3 0.659 88.7 63.2 -64.7 -15.7 29.2 15.7 0.9 15 98 A D T X + 0 0 43 -3,-2.4 3,-2.5 1,-0.2 -1,-0.2 0.319 67.8 112.8 -89.6 9.1 26.9 12.7 1.5 16 99 A V T < S+ 0 0 5 -3,-1.4 -1,-0.2 1,-0.3 -2,-0.1 0.745 73.8 52.9 -58.9 -25.5 27.1 13.1 5.3 17 100 A N T 3 S+ 0 0 77 -3,-0.4 2,-0.4 -4,-0.1 -1,-0.3 0.334 95.8 94.0 -88.7 7.7 23.4 14.2 5.7 18 101 A K S X S- 0 0 121 -3,-2.5 3,-1.2 0, 0.0 2,-0.5 -0.830 75.8-127.2-110.4 142.0 22.2 11.1 3.7 19 102 A W T 3 S+ 0 0 54 -2,-0.4 -2,-0.1 1,-0.2 69,-0.0 -0.697 103.2 40.6 -75.8 122.5 21.0 7.7 4.9 20 103 A G T 3 S+ 0 0 14 -2,-0.5 -1,-0.2 1,-0.2 221,-0.0 0.542 75.9 171.6 105.8 7.7 23.2 5.3 2.9 21 104 A L < - 0 0 3 -3,-1.2 2,-2.2 -6,-0.2 3,-0.2 -0.214 45.5-114.0 -39.6 132.4 26.5 7.3 3.1 22 105 A H > + 0 0 68 1,-0.2 4,-2.5 -10,-0.2 5,-0.2 -0.501 49.5 167.8 -75.7 77.6 29.3 5.0 1.7 23 106 A V H > + 0 0 1 -2,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.838 69.8 53.7 -71.3 -32.5 31.0 4.7 5.0 24 107 A F H > S+ 0 0 24 -3,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.893 109.1 49.6 -65.7 -35.5 33.3 1.9 4.0 25 108 A R H > S+ 0 0 132 2,-0.2 4,-3.2 1,-0.2 5,-0.3 0.933 110.3 51.0 -66.6 -45.9 34.5 4.0 1.0 26 109 A I H X S+ 0 0 0 -4,-2.5 4,-1.9 1,-0.2 7,-0.3 0.918 108.8 52.4 -57.1 -38.6 35.1 6.9 3.5 27 110 A A H <>S+ 0 0 5 -4,-2.3 5,-2.9 2,-0.2 6,-0.5 0.952 113.3 42.6 -62.9 -48.6 37.0 4.5 5.7 28 111 A E H ><5S+ 0 0 163 -4,-2.4 3,-1.4 1,-0.2 -2,-0.2 0.965 117.1 46.1 -62.2 -48.5 39.3 3.4 2.8 29 112 A L H 3<5S+ 0 0 65 -4,-3.2 -1,-0.2 1,-0.3 -2,-0.2 0.701 108.4 56.0 -71.7 -19.6 39.7 7.0 1.4 30 113 A S T 3<5S- 0 0 20 -4,-1.9 -1,-0.3 -5,-0.3 -2,-0.2 0.397 119.9-105.4 -90.2 4.6 40.4 8.6 4.8 31 114 A G T < 5S- 0 0 61 -3,-1.4 -3,-0.2 -4,-0.2 -2,-0.1 0.896 80.5 -47.9 71.2 42.3 43.3 6.2 5.4 32 115 A N S + 0 0 68 -6,-0.5 4,-2.0 -7,-0.3 5,-0.3 -0.327 21.0 138.8-123.5 48.1 40.0 7.3 9.9 34 117 A P H > S+ 0 0 0 0, 0.0 4,-2.2 0, 0.0 5,-0.3 0.890 72.6 53.3 -62.5 -32.6 36.3 7.3 9.1 35 118 A L H > S+ 0 0 0 1,-0.2 4,-2.7 2,-0.2 5,-0.3 0.959 110.3 47.9 -69.9 -43.3 35.4 8.3 12.7 36 119 A T H > S+ 0 0 11 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.944 117.1 38.0 -62.5 -49.9 37.7 11.3 12.7 37 120 A V H X S+ 0 0 33 -4,-2.0 4,-2.3 1,-0.2 -1,-0.2 0.851 117.4 50.1 -77.0 -31.5 36.7 12.9 9.4 38 121 A I H X S+ 0 0 0 -4,-2.2 4,-2.6 -5,-0.3 -1,-0.2 0.936 113.4 46.1 -69.9 -42.8 33.0 12.1 9.8 39 122 A M H X S+ 0 0 0 -4,-2.7 4,-3.2 -5,-0.3 5,-0.2 0.935 114.0 49.0 -62.3 -47.8 32.9 13.6 13.3 40 123 A H H X S+ 0 0 40 -4,-2.5 4,-2.6 -5,-0.3 5,-0.2 0.964 112.1 47.6 -59.4 -46.0 34.8 16.7 12.1 41 124 A T H X S+ 0 0 26 -4,-2.3 4,-3.0 2,-0.2 -1,-0.2 0.922 113.2 48.7 -59.7 -46.9 32.5 17.1 9.1 42 125 A I H X S+ 0 0 0 -4,-2.6 4,-2.4 2,-0.2 6,-0.3 0.952 110.5 50.6 -61.6 -44.0 29.4 16.8 11.4 43 126 A F H <>S+ 0 0 0 -4,-3.2 5,-2.4 1,-0.2 6,-0.6 0.908 114.6 43.8 -60.6 -42.6 30.8 19.3 14.0 44 127 A Q H ><5S+ 0 0 108 -4,-2.6 3,-1.2 -5,-0.2 -1,-0.2 0.934 112.9 52.3 -64.1 -47.0 31.5 21.9 11.2 45 128 A E H 3<5S+ 0 0 110 -4,-3.0 -2,-0.2 1,-0.3 -1,-0.2 0.857 115.5 39.9 -59.5 -37.1 28.1 21.2 9.6 46 129 A R T 3<5S- 0 0 52 -4,-2.4 -1,-0.3 -5,-0.2 -2,-0.2 0.403 109.7-123.9 -92.6 -1.3 26.3 21.7 12.9 47 130 A D T <>5 + 0 0 79 -3,-1.2 4,-2.2 -4,-0.4 -3,-0.2 0.749 62.5 145.8 65.2 28.9 28.5 24.7 13.8 48 131 A L H >< + 0 0 1 -5,-2.4 4,-1.8 -6,-0.3 6,-0.4 0.729 61.0 59.4 -69.9 -27.7 29.5 22.9 17.0 49 132 A L H 4>S+ 0 0 28 -6,-0.6 5,-1.9 2,-0.2 4,-0.2 0.927 111.8 41.0 -67.5 -43.5 33.1 24.1 17.2 50 133 A K H >45S+ 0 0 156 3,-0.2 3,-1.0 2,-0.2 -2,-0.2 0.934 113.9 51.8 -65.6 -51.2 31.9 27.7 17.2 51 134 A T H 3<5S+ 0 0 61 -4,-2.2 -2,-0.2 1,-0.2 -1,-0.2 0.854 124.5 27.3 -58.0 -39.1 28.9 27.2 19.6 52 135 A F T 3<5S- 0 0 10 -4,-1.8 116,-0.4 -5,-0.1 -1,-0.2 0.196 105.6-120.2-110.8 13.8 31.1 25.4 22.3 53 136 A K T < 5 + 0 0 156 -3,-1.0 -3,-0.2 -4,-0.2 -4,-0.1 0.879 46.7 173.3 42.7 49.6 34.4 27.1 21.4 54 137 A I < - 0 0 8 -5,-1.9 2,-0.3 -6,-0.4 -1,-0.2 -0.761 32.5-129.1 -81.4 119.5 36.1 23.8 20.6 55 138 A P >> - 0 0 49 0, 0.0 4,-2.2 0, 0.0 3,-1.3 -0.577 16.1-131.1 -67.0 127.0 39.5 24.5 19.2 56 139 A V H 3> S+ 0 0 65 -2,-0.3 4,-2.8 1,-0.3 5,-0.2 0.845 106.3 52.0 -52.3 -40.6 39.8 22.5 15.9 57 140 A D H 3> S+ 0 0 117 2,-0.2 4,-2.1 1,-0.2 -1,-0.3 0.815 109.1 51.6 -69.4 -26.1 43.3 21.0 16.8 58 141 A T H <> S+ 0 0 4 -3,-1.3 4,-2.5 2,-0.2 5,-0.2 0.933 110.7 48.0 -70.6 -45.4 41.8 19.9 20.2 59 142 A L H X S+ 0 0 0 -4,-2.2 4,-3.0 1,-0.2 -2,-0.2 0.951 114.1 45.9 -59.9 -48.4 38.9 18.2 18.3 60 143 A I H X S+ 0 0 43 -4,-2.8 4,-2.6 1,-0.2 -1,-0.2 0.933 112.7 50.0 -60.7 -46.0 41.2 16.5 15.9 61 144 A T H X S+ 0 0 39 -4,-2.1 4,-1.8 1,-0.2 -1,-0.2 0.900 114.0 44.9 -63.1 -40.5 43.6 15.4 18.6 62 145 A Y H X S+ 0 0 0 -4,-2.5 4,-2.9 100,-0.3 5,-0.2 0.927 112.2 52.5 -65.6 -44.8 40.7 13.9 20.7 63 146 A L H X S+ 0 0 0 -4,-3.0 4,-3.2 -5,-0.2 -2,-0.2 0.915 108.5 50.6 -58.1 -42.3 39.2 12.3 17.6 64 147 A M H X S+ 0 0 78 -4,-2.6 4,-3.0 2,-0.2 -1,-0.2 0.908 113.1 44.3 -62.7 -46.8 42.5 10.6 16.7 65 148 A T H X S+ 0 0 16 -4,-1.8 4,-1.0 2,-0.2 -2,-0.2 0.935 114.3 49.6 -64.2 -46.0 43.0 9.1 20.2 66 149 A L H >< S+ 0 0 0 -4,-2.9 3,-1.8 2,-0.2 4,-0.5 0.985 113.8 46.0 -57.4 -52.3 39.4 8.0 20.4 67 150 A E H >< S+ 0 0 3 -4,-3.2 3,-1.6 1,-0.3 -2,-0.2 0.922 107.0 58.8 -59.0 -40.5 39.7 6.4 17.0 68 151 A D H 3< S+ 0 0 99 -4,-3.0 -1,-0.3 1,-0.2 -2,-0.2 0.738 99.9 59.7 -55.7 -20.7 43.0 4.8 18.0 69 152 A H T << S+ 0 0 63 -3,-1.8 51,-1.1 -4,-1.0 2,-0.4 0.454 83.5 87.5 -98.4 -2.0 41.2 3.1 20.9 70 153 A Y S < S- 0 0 10 -3,-1.6 2,-0.5 -4,-0.5 8,-0.1 -0.771 90.4-115.8 -80.6 144.0 38.8 1.2 18.7 71 154 A H > - 0 0 54 6,-0.5 3,-1.0 50,-0.4 8,-0.1 -0.694 18.4-159.1 -88.1 123.3 40.5 -2.1 17.7 72 155 A A T 3 S+ 0 0 75 -2,-0.5 -1,-0.1 1,-0.2 6,-0.1 0.751 91.7 63.4 -77.7 -15.2 41.3 -2.5 14.0 73 156 A D T 3 S+ 0 0 118 2,-0.0 2,-0.6 5,-0.0 -1,-0.2 0.466 82.9 93.3 -81.7 2.8 41.5 -6.3 14.5 74 157 A V < - 0 0 7 -3,-1.0 49,-0.1 1,-0.1 182,-0.1 -0.861 68.5-150.6 -97.5 123.3 37.8 -6.5 15.5 75 158 A A S S+ 0 0 7 -2,-0.6 178,-0.2 177,-0.1 3,-0.2 0.890 84.4 8.5 -63.3 -43.0 35.6 -7.2 12.4 76 159 A Y S S+ 0 0 16 176,-0.3 2,-2.4 1,-0.2 5,-0.5 0.877 118.6 59.1-106.0 -57.6 32.4 -5.3 13.5 77 160 A H S S+ 0 0 31 175,-0.1 -6,-0.5 4,-0.1 44,-0.2 -0.376 85.4 107.8 -77.5 71.6 32.8 -3.3 16.7 78 161 A N S > S- 0 0 6 -2,-2.4 4,-2.1 -3,-0.2 3,-0.3 -0.586 89.2 -68.4-133.8-171.2 35.5 -1.0 15.3 79 162 A N H > S+ 0 0 6 1,-0.2 4,-2.1 2,-0.2 5,-0.1 0.712 126.5 56.9 -57.5 -24.9 36.0 2.6 14.2 80 163 A I H > S+ 0 0 11 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.910 106.3 48.1 -78.2 -42.2 33.9 2.1 11.1 81 164 A H H > S+ 0 0 0 -5,-0.5 4,-2.6 -3,-0.3 5,-0.3 0.963 112.0 51.1 -58.7 -44.9 30.9 1.0 13.1 82 165 A A H X S+ 0 0 0 -4,-2.1 4,-2.6 1,-0.2 -2,-0.2 0.923 110.0 49.0 -56.4 -45.5 31.4 4.0 15.5 83 166 A A H X S+ 0 0 0 -4,-2.1 4,-2.4 1,-0.2 -1,-0.2 0.901 111.3 50.6 -61.7 -39.3 31.5 6.3 12.4 84 167 A D H X S+ 0 0 3 -4,-2.3 4,-2.7 2,-0.2 -2,-0.2 0.874 110.8 47.5 -66.1 -40.6 28.3 4.7 11.1 85 168 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 2,-0.2 5,-0.2 0.950 113.3 49.6 -67.4 -43.0 26.4 5.2 14.4 86 169 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 -5,-0.3 -2,-0.2 0.928 114.9 43.4 -56.4 -49.8 27.6 8.8 14.6 87 170 A Q H X S+ 0 0 1 -4,-2.4 4,-1.6 2,-0.2 -1,-0.2 0.876 113.1 51.4 -69.5 -37.0 26.5 9.5 11.0 88 171 A S H X S+ 0 0 0 -4,-2.7 4,-2.6 2,-0.2 -2,-0.2 0.913 110.4 48.3 -67.8 -38.0 23.2 7.7 11.5 89 172 A T H X S+ 0 0 0 -4,-2.5 4,-2.7 1,-0.2 5,-0.2 0.934 107.4 58.1 -63.6 -42.9 22.4 9.6 14.7 90 173 A H H X S+ 0 0 2 -4,-2.5 4,-0.5 -5,-0.2 -1,-0.2 0.897 109.2 43.4 -54.7 -39.7 23.3 12.8 12.8 91 174 A V H >< S+ 0 0 29 -4,-1.6 3,-1.3 1,-0.2 -1,-0.2 0.934 112.1 51.6 -72.3 -47.8 20.6 12.1 10.2 92 175 A L H >< S+ 0 0 2 -4,-2.6 3,-1.7 1,-0.3 -2,-0.2 0.854 102.3 62.2 -56.2 -33.7 18.0 11.0 12.7 93 176 A L H 3< S+ 0 0 13 -4,-2.7 -1,-0.3 1,-0.3 -2,-0.2 0.794 102.8 52.4 -62.1 -24.3 18.6 14.3 14.6 94 177 A S T << S+ 0 0 70 -3,-1.3 -1,-0.3 -4,-0.5 -2,-0.2 0.280 75.5 130.0-100.3 10.0 17.5 16.1 11.5 95 178 A T X - 0 0 19 -3,-1.7 3,-1.9 1,-0.1 4,-0.1 -0.399 67.3-120.9 -60.9 142.4 14.1 14.4 10.9 96 179 A P G > S+ 0 0 84 0, 0.0 3,-2.4 0, 0.0 -1,-0.1 0.865 109.7 64.2 -53.3 -41.0 11.3 16.9 10.4 97 180 A A G 3 S+ 0 0 4 208,-0.3 118,-3.0 1,-0.3 209,-0.1 0.701 108.2 44.2 -57.4 -17.1 9.3 15.6 13.4 98 181 A L G X> S+ 0 0 4 -3,-1.9 3,-1.9 116,-0.2 4,-0.6 0.173 80.8 152.2-112.3 13.0 12.2 16.8 15.6 99 182 A E T <4 S- 0 0 128 -3,-2.4 -5,-0.1 1,-0.3 -4,-0.0 -0.218 80.3 -15.0 -51.2 122.2 12.8 20.2 13.9 100 183 A A T 34 S+ 0 0 92 1,-0.1 -1,-0.3 2,-0.1 -6,-0.1 0.508 103.1 120.9 58.1 8.3 14.3 22.6 16.4 101 184 A V T <4 + 0 0 20 -3,-1.9 2,-0.3 2,-0.0 -2,-0.1 0.896 58.7 60.4 -66.3 -44.7 13.4 20.3 19.3 102 185 A F S < S- 0 0 19 -4,-0.6 -2,-0.1 -9,-0.2 2,-0.0 -0.640 78.2-126.7 -95.4 143.2 16.9 19.7 20.8 103 186 A T > - 0 0 70 -2,-0.3 4,-1.4 1,-0.1 5,-0.1 -0.339 33.3-105.1 -73.4 169.7 19.3 22.2 22.3 104 187 A D H > S+ 0 0 80 1,-0.2 4,-2.7 2,-0.2 5,-0.1 0.772 121.4 55.2 -62.2 -30.2 22.8 22.3 21.0 105 188 A L H > S+ 0 0 24 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.877 106.6 48.9 -75.3 -37.5 24.1 20.7 24.2 106 189 A E H > S+ 0 0 18 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.801 111.7 50.6 -69.6 -31.6 21.7 17.8 23.7 107 190 A I H X S+ 0 0 20 -4,-1.4 4,-2.2 2,-0.2 5,-0.3 0.937 109.7 49.9 -72.5 -47.3 22.9 17.4 20.1 108 191 A L H X S+ 0 0 0 -4,-2.7 4,-2.9 1,-0.2 5,-0.3 0.885 110.8 50.7 -49.9 -44.9 26.5 17.4 21.2 109 192 A A H X S+ 0 0 0 -4,-2.0 4,-2.9 1,-0.2 -1,-0.2 0.894 110.0 48.4 -67.7 -42.0 25.7 14.8 23.8 110 193 A A H X S+ 0 0 0 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.902 117.0 41.1 -66.9 -38.1 24.0 12.5 21.3 111 194 A I H X S+ 0 0 0 -4,-2.2 4,-2.3 2,-0.2 -2,-0.2 0.922 117.1 47.6 -77.0 -45.1 26.8 12.7 18.7 112 195 A F H X S+ 0 0 0 -4,-2.9 4,-1.9 -5,-0.3 -2,-0.2 0.942 111.6 51.4 -58.3 -45.7 29.5 12.5 21.3 113 196 A A H X S+ 0 0 0 -4,-2.9 4,-1.2 -5,-0.3 -2,-0.2 0.934 110.4 48.8 -57.1 -49.9 27.7 9.5 22.9 114 197 A S H < S+ 0 0 0 -4,-2.0 3,-0.4 1,-0.2 -28,-0.3 0.910 109.0 55.2 -53.4 -41.0 27.5 7.7 19.4 115 198 A A H < S+ 0 0 0 -4,-2.3 3,-0.3 1,-0.2 -1,-0.2 0.877 118.9 29.4 -65.3 -38.5 31.2 8.4 18.9 116 199 A I H >< S+ 0 0 0 -4,-1.9 3,-1.6 -3,-0.2 -1,-0.2 0.462 87.6 108.0 -97.8 -1.3 32.3 6.7 22.1 117 200 A H T 3< S+ 0 0 0 -4,-1.2 33,-0.2 -3,-0.4 -1,-0.2 0.647 93.7 21.7 -63.7 -12.9 29.6 4.1 22.5 118 201 A D T > S+ 0 0 10 -3,-0.3 3,-1.5 -4,-0.2 -1,-0.3 0.234 84.2 151.5-132.7 8.5 31.8 1.1 21.6 119 202 A V T < S+ 0 0 0 -3,-1.6 -49,-0.2 1,-0.2 34,-0.2 -0.130 72.4 8.4 -48.1 135.6 35.3 2.4 22.3 120 203 A D T 3 S+ 0 0 46 -51,-1.1 -1,-0.2 -54,-0.2 -50,-0.2 0.729 83.7 169.2 64.1 26.2 37.8 -0.3 23.3 121 204 A H < - 0 0 13 -3,-1.5 -50,-0.4 -44,-0.2 -1,-0.2 -0.519 27.7-152.0 -65.9 130.5 35.4 -3.1 22.4 122 205 A P - 0 0 38 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.459 40.0-106.1 -87.3 0.6 37.3 -6.4 22.5 123 206 A G S S+ 0 0 8 1,-0.3 2,-0.3 -46,-0.1 137,-0.1 0.689 90.2 98.8 86.5 15.2 35.0 -8.3 19.9 124 207 A V S S- 0 0 3 136,-0.1 -1,-0.3 135,-0.0 133,-0.1 -0.955 73.1-109.2-135.9 151.7 33.4 -10.5 22.6 125 208 A S > - 0 0 44 -2,-0.3 4,-1.9 -3,-0.1 3,-0.2 -0.240 27.7-106.9 -78.3 168.2 30.0 -10.0 24.3 126 209 A N H > S+ 0 0 31 1,-0.2 4,-2.5 2,-0.2 3,-0.2 0.944 120.9 55.8 -50.9 -46.2 29.2 -9.1 27.9 127 210 A Q H > S+ 0 0 106 1,-0.3 4,-2.7 2,-0.2 -1,-0.2 0.824 105.9 49.1 -64.1 -35.4 28.2 -12.7 28.5 128 211 A F H > S+ 0 0 3 2,-0.2 4,-1.6 -3,-0.2 -1,-0.3 0.864 110.4 50.4 -68.3 -42.4 31.5 -14.0 27.3 129 212 A L H <>S+ 0 0 15 -4,-1.9 5,-2.6 -3,-0.2 8,-0.2 0.898 113.8 46.3 -63.1 -40.7 33.4 -11.6 29.6 130 213 A I H ><5S+ 0 0 31 -4,-2.5 3,-2.3 3,-0.2 -2,-0.2 0.986 113.2 48.9 -60.2 -58.2 31.2 -12.7 32.6 131 214 A N H 3<5S+ 0 0 86 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.703 112.2 47.9 -54.5 -29.9 31.6 -16.4 31.8 132 215 A T T 3<5S- 0 0 21 -4,-1.6 -1,-0.3 -5,-0.1 -2,-0.2 0.218 110.3-122.4 -94.7 11.1 35.3 -16.2 31.5 133 216 A N T < 5 - 0 0 144 -3,-2.3 -3,-0.2 1,-0.1 -2,-0.1 0.903 45.1-174.0 50.0 51.0 35.6 -14.2 34.8 134 217 A S >< - 0 0 23 -5,-2.6 4,-1.9 -6,-0.1 5,-0.1 -0.236 37.4-111.4 -74.5 167.3 37.3 -11.3 33.0 135 218 A E H > S+ 0 0 174 1,-0.2 4,-2.6 2,-0.2 -1,-0.1 0.814 118.0 52.4 -68.7 -32.4 38.8 -8.2 34.8 136 219 A L H > S+ 0 0 40 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.895 108.3 48.9 -68.5 -44.2 36.1 -6.0 33.3 137 220 A A H 4>S+ 0 0 2 -8,-0.2 5,-2.1 2,-0.2 4,-0.3 0.866 114.2 47.7 -63.8 -35.1 33.3 -8.2 34.5 138 221 A L H ><5S+ 0 0 134 -4,-1.9 3,-0.9 3,-0.2 -2,-0.2 0.944 113.1 48.5 -67.4 -49.5 34.9 -8.2 38.0 139 222 A M H 3<5S+ 0 0 131 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.885 119.9 36.7 -50.8 -48.4 35.3 -4.5 37.9 140 223 A Y T ><5S- 0 0 54 -4,-2.6 3,-1.8 -5,-0.1 -1,-0.2 0.214 106.5-117.7-101.3 12.3 31.7 -3.9 36.8 141 224 A N T < 5 - 0 0 133 -3,-0.9 -3,-0.2 -4,-0.3 -4,-0.1 0.861 64.8 -67.8 55.0 42.6 29.9 -6.6 38.8 142 225 A D T 3 S+ 0 0 17 -2,-0.5 4,-2.5 3,-0.1 5,-0.3 0.908 81.5 173.9 40.5 50.8 26.5 -3.5 31.6 145 228 A V H > + 0 0 0 1,-0.2 4,-1.9 -3,-0.2 5,-0.1 0.942 66.9 33.2 -58.3 -54.5 30.1 -4.5 31.6 146 229 A L H > S+ 0 0 3 2,-0.2 4,-2.9 1,-0.2 5,-0.2 0.917 117.0 54.2 -70.3 -40.4 31.2 -3.2 28.1 147 230 A E H > S+ 0 0 21 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.924 109.2 48.5 -65.4 -39.5 28.9 -0.2 28.1 148 231 A N H X S+ 0 0 49 -4,-2.5 4,-2.4 1,-0.2 -1,-0.2 0.930 113.2 49.7 -57.2 -43.7 30.3 1.0 31.5 149 232 A H H X S+ 0 0 26 -4,-1.9 4,-2.9 -5,-0.3 5,-0.3 0.914 106.3 54.3 -65.6 -42.0 33.8 0.5 30.0 150 233 A H H X S+ 0 0 0 -4,-2.9 4,-2.7 2,-0.2 -1,-0.2 0.920 111.2 46.7 -55.7 -44.1 33.0 2.5 26.8 151 234 A L H X S+ 0 0 10 -4,-1.9 4,-2.5 -5,-0.2 5,-0.3 0.972 112.3 48.5 -63.8 -49.4 31.9 5.5 28.9 152 235 A A H X S+ 0 0 44 -4,-2.4 4,-2.4 1,-0.2 -2,-0.2 0.896 115.1 44.7 -65.9 -40.4 34.9 5.4 31.2 153 236 A V H X S+ 0 0 22 -4,-2.9 4,-2.3 2,-0.2 -1,-0.2 0.968 112.6 51.2 -65.0 -49.0 37.4 5.1 28.3 154 237 A G H X S+ 0 0 0 -4,-2.7 4,-0.5 -5,-0.3 -2,-0.2 0.872 116.6 40.5 -59.7 -38.5 35.6 7.9 26.2 155 238 A F H >< S+ 0 0 12 -4,-2.5 3,-1.1 -5,-0.2 4,-0.3 0.921 113.0 53.8 -71.6 -44.8 35.6 10.3 29.2 156 239 A K H >< S+ 0 0 146 -4,-2.4 3,-2.1 -5,-0.3 4,-0.2 0.869 99.3 61.9 -60.6 -36.3 39.1 9.4 30.4 157 240 A L H >< S+ 0 0 9 -4,-2.3 3,-1.7 1,-0.3 -1,-0.3 0.777 88.0 73.5 -62.6 -26.5 40.6 10.1 26.9 158 241 A L T << S+ 0 0 5 -3,-1.1 -1,-0.3 -4,-0.5 5,-0.3 0.685 89.1 61.7 -54.5 -22.8 39.5 13.7 27.3 159 242 A Q T < S+ 0 0 161 -3,-2.1 -1,-0.2 -4,-0.3 -2,-0.2 0.483 79.5 107.6 -87.5 -7.2 42.3 14.2 29.9 160 243 A E S X S- 0 0 91 -3,-1.7 3,-2.5 -4,-0.2 4,-0.3 -0.341 92.5 -64.7 -68.2 156.6 45.1 13.4 27.4 161 244 A E T 3 S- 0 0 174 1,-0.3 -1,-0.2 2,-0.1 -2,-0.1 -0.131 119.5 -9.8 -46.0 120.2 47.3 16.3 26.2 162 245 A N T 3 S+ 0 0 80 -3,-0.1 -100,-0.3 1,-0.1 -1,-0.3 0.743 105.0 112.5 57.5 30.0 45.2 18.7 24.2 163 246 A C < + 0 0 2 -3,-2.5 2,-1.9 -5,-0.3 -2,-0.1 0.461 33.6 112.1-108.0 -1.6 42.2 16.3 24.1 164 247 A D > + 0 0 53 -4,-0.3 3,-1.8 1,-0.2 4,-0.1 -0.467 31.1 168.6 -80.2 85.5 39.6 18.2 26.2 165 248 A I T 3 S+ 0 0 1 -2,-1.9 3,-0.3 1,-0.3 -1,-0.2 0.603 78.3 55.9 -70.7 -11.2 37.0 19.2 23.6 166 249 A F T > S+ 0 0 4 1,-0.2 3,-1.8 -3,-0.1 -1,-0.3 0.198 70.2 114.4-103.3 12.7 34.7 20.3 26.6 167 250 A Q T < S+ 0 0 93 -3,-1.8 -1,-0.2 1,-0.3 -2,-0.1 0.751 80.7 43.4 -56.1 -27.2 37.3 22.7 28.1 168 251 A N T 3 S+ 0 0 90 -116,-0.4 -1,-0.3 -3,-0.3 2,-0.2 0.194 85.0 106.9-108.5 14.1 35.0 25.7 27.3 169 252 A L S < S- 0 0 16 -3,-1.8 2,-0.1 1,-0.1 -117,-0.0 -0.618 80.5-108.5 -75.7 151.4 31.7 24.3 28.4 170 253 A T > - 0 0 80 -2,-0.2 4,-2.7 1,-0.1 5,-0.2 -0.395 33.4-103.6 -70.6 163.1 30.6 25.9 31.7 171 254 A K H > S+ 0 0 182 1,-0.2 4,-1.8 2,-0.2 -1,-0.1 0.851 125.5 49.6 -53.6 -35.5 30.7 23.5 34.7 172 255 A K H > S+ 0 0 147 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.870 108.8 50.5 -77.8 -39.5 27.0 23.2 34.5 173 256 A Q H > S+ 0 0 60 2,-0.2 4,-2.8 1,-0.2 5,-0.2 0.951 111.7 48.8 -54.9 -52.0 27.1 22.4 30.7 174 257 A R H X S+ 0 0 74 -4,-2.7 4,-2.6 1,-0.2 -2,-0.2 0.876 111.1 51.0 -58.6 -38.7 29.7 19.7 31.3 175 258 A Q H X S+ 0 0 132 -4,-1.8 4,-2.0 -5,-0.2 -1,-0.2 0.912 113.0 44.0 -68.4 -42.3 27.6 18.2 34.1 176 259 A S H X S+ 0 0 40 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.913 114.2 50.1 -68.1 -42.4 24.4 18.0 32.0 177 260 A L H X S+ 0 0 0 -4,-2.8 4,-3.3 2,-0.2 5,-0.3 0.973 110.8 49.5 -56.5 -55.9 26.4 16.6 29.0 178 261 A R H X S+ 0 0 106 -4,-2.6 4,-2.6 1,-0.2 5,-0.2 0.902 111.4 49.4 -50.2 -46.6 28.0 14.0 31.1 179 262 A K H X S+ 0 0 108 -4,-2.0 4,-2.2 1,-0.2 -1,-0.2 0.919 114.1 44.9 -60.1 -48.9 24.6 13.0 32.6 180 263 A M H X S+ 0 0 7 -4,-2.5 4,-2.5 2,-0.2 -2,-0.2 0.931 112.4 50.9 -62.7 -45.3 23.1 12.7 29.1 181 264 A V H X S+ 0 0 0 -4,-3.3 4,-2.8 1,-0.2 5,-0.3 0.921 111.2 48.3 -61.9 -42.8 26.0 10.8 27.6 182 265 A I H X S+ 0 0 44 -4,-2.6 4,-2.3 -5,-0.3 5,-0.3 0.937 111.8 49.4 -61.3 -47.4 25.9 8.3 30.4 183 266 A D H X S+ 0 0 53 -4,-2.2 4,-1.0 -5,-0.2 -1,-0.2 0.877 113.7 47.1 -59.1 -41.0 22.2 7.8 30.1 184 267 A I H < S+ 0 0 1 -4,-2.5 4,-0.4 2,-0.2 -2,-0.2 0.947 114.7 43.6 -68.6 -46.1 22.5 7.3 26.3 185 268 A V H >< S+ 0 0 0 -4,-2.8 3,-1.7 1,-0.2 4,-0.2 0.899 109.7 54.6 -73.1 -35.4 25.3 4.9 26.3 186 269 A L H >< S+ 0 0 54 -4,-2.3 3,-1.5 -5,-0.3 -1,-0.2 0.871 102.7 60.1 -65.0 -28.2 24.0 2.7 29.1 187 270 A A T 3< S+ 0 0 8 -4,-1.0 -1,-0.3 -5,-0.3 -2,-0.2 0.614 86.8 74.0 -75.9 -12.6 20.9 2.4 27.1 188 271 A T T < + 0 0 6 -3,-1.7 2,-0.4 -4,-0.4 -1,-0.3 0.528 67.9 116.4 -70.6 -7.4 22.8 0.7 24.2 189 272 A D X - 0 0 8 -3,-1.5 3,-2.3 -4,-0.2 4,-0.2 -0.523 64.7-146.3 -66.1 117.2 23.0 -2.4 26.4 190 273 A M G > S+ 0 0 81 -2,-0.4 3,-1.7 1,-0.3 4,-0.4 0.794 96.9 66.4 -60.5 -28.6 21.0 -5.1 24.5 191 274 A S G 3 S+ 0 0 92 1,-0.3 -1,-0.3 2,-0.1 4,-0.2 0.662 101.2 52.4 -64.9 -10.1 19.8 -6.6 27.7 192 275 A K G <> S+ 0 0 102 -3,-2.3 4,-2.5 1,-0.1 -1,-0.3 0.500 84.2 94.3 -96.8 -4.7 17.9 -3.3 28.2 193 276 A H H <> S+ 0 0 2 -3,-1.7 4,-2.6 1,-0.2 5,-0.3 0.866 77.7 53.1 -64.0 -42.1 16.3 -3.5 24.7 194 277 A M H > S+ 0 0 117 -4,-0.4 4,-2.8 1,-0.2 -1,-0.2 0.950 115.8 39.9 -65.1 -43.9 13.0 -5.1 25.7 195 278 A N H > S+ 0 0 115 -4,-0.2 4,-3.0 2,-0.2 5,-0.2 0.897 112.7 55.4 -70.3 -38.1 12.2 -2.5 28.4 196 279 A L H X S+ 0 0 22 -4,-2.5 4,-1.9 2,-0.2 -2,-0.2 0.951 114.0 41.8 -55.0 -48.6 13.5 0.4 26.3 197 280 A L H X S+ 0 0 13 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.925 112.0 53.1 -67.3 -47.5 11.1 -0.6 23.5 198 281 A A H X S+ 0 0 43 -4,-2.8 4,-1.7 -5,-0.3 -2,-0.2 0.949 113.9 44.2 -52.8 -46.7 8.2 -1.3 25.8 199 282 A D H X S+ 0 0 92 -4,-3.0 4,-1.8 1,-0.2 -1,-0.2 0.790 109.2 56.3 -71.6 -28.1 8.6 2.2 27.4 200 283 A L H X S+ 0 0 0 -4,-1.9 4,-1.7 -5,-0.2 -1,-0.2 0.910 105.9 51.1 -65.7 -42.7 9.1 3.8 24.0 201 284 A K H X S+ 0 0 101 -4,-2.4 4,-1.8 1,-0.2 -2,-0.2 0.923 108.7 52.8 -58.3 -44.4 5.7 2.4 22.9 202 285 A T H X S+ 0 0 80 -4,-1.7 4,-1.1 1,-0.2 -1,-0.2 0.915 109.7 47.0 -57.3 -45.0 4.1 3.8 26.0 203 286 A M H < S+ 0 0 18 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.802 107.9 56.1 -73.4 -24.3 5.4 7.3 25.4 204 287 A V H >< S+ 0 0 16 -4,-1.7 3,-1.2 1,-0.2 -1,-0.2 0.865 98.9 62.8 -70.7 -35.7 4.3 7.2 21.7 205 288 A E H 3< S+ 0 0 153 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.906 115.9 29.3 -53.6 -44.1 0.7 6.4 22.9 206 289 A T T 3< S+ 0 0 110 -4,-1.1 -1,-0.3 2,-0.1 -2,-0.2 0.123 88.8 140.0-108.1 21.3 0.5 9.8 24.7 207 290 A K < - 0 0 70 -3,-1.2 2,-0.4 -5,-0.1 10,-0.1 -0.282 39.7-146.5 -62.6 152.1 2.9 11.8 22.5 208 291 A K - 0 0 147 8,-0.5 8,-2.8 0, 0.0 2,-0.3 -0.971 15.2-172.9-122.9 137.8 1.9 15.4 21.6 209 292 A V B -A 215 0A 68 -2,-0.4 6,-0.2 6,-0.2 2,-0.1 -0.904 27.1-114.2-125.8 151.6 2.6 17.2 18.3 210 293 A T > - 0 0 47 4,-2.9 3,-2.0 -2,-0.3 6,-0.0 -0.414 47.2 -98.3 -70.7 165.4 2.3 20.7 17.0 211 294 A S T 3 S+ 0 0 139 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.772 126.1 56.0 -58.2 -29.2 -0.3 21.0 14.1 212 295 A S T 3 S- 0 0 102 2,-0.1 -1,-0.3 -115,-0.0 -2,-0.0 0.342 125.8 -99.1 -88.8 6.1 2.5 20.9 11.6 213 296 A G S < S+ 0 0 30 -3,-2.0 2,-0.4 1,-0.3 -2,-0.1 0.469 73.3 141.8 98.5 2.7 3.8 17.5 13.0 214 297 A V - 0 0 30 -116,-0.1 -4,-2.9 1,-0.1 -1,-0.3 -0.644 52.2-117.6 -78.8 128.7 6.7 18.6 15.3 215 298 A L B -A 209 0A 4 -118,-3.0 2,-0.6 -2,-0.4 -6,-0.2 -0.364 17.8-138.0 -62.0 138.3 7.0 16.6 18.6 216 299 A L + 0 0 79 -8,-2.8 -8,-0.5 -2,-0.1 2,-0.4 -0.906 24.9 174.0 -99.5 122.1 6.6 18.4 21.8 217 300 A L + 0 0 13 -2,-0.6 -2,-0.0 1,-0.1 -10,-0.0 -0.860 2.2 171.0-131.5 97.1 9.1 17.3 24.4 218 301 A D + 0 0 143 -2,-0.4 2,-0.3 5,-0.0 -1,-0.1 0.657 55.1 41.1 -86.2 -25.3 8.8 19.5 27.5 219 302 A N S > S- 0 0 65 1,-0.1 4,-2.3 0, 0.0 3,-0.4 -0.862 81.0-106.8-129.3 163.2 11.0 17.8 30.1 220 303 A Y H > S+ 0 0 68 -2,-0.3 4,-3.8 1,-0.2 5,-0.3 0.872 114.5 57.5 -48.0 -49.5 14.4 16.0 30.6 221 304 A S H > S+ 0 0 81 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.888 111.9 39.1 -53.8 -47.2 12.7 12.6 30.9 222 305 A D H > S+ 0 0 53 -3,-0.4 4,-1.7 2,-0.2 -1,-0.2 0.908 118.1 49.2 -73.3 -42.6 11.0 12.8 27.5 223 306 A R H X S+ 0 0 41 -4,-2.3 4,-1.9 1,-0.2 -2,-0.2 0.941 112.9 45.6 -58.8 -51.2 14.0 14.4 25.8 224 307 A I H X S+ 0 0 12 -4,-3.8 4,-2.6 1,-0.2 5,-0.2 0.880 109.7 56.1 -65.5 -33.6 16.5 11.9 27.2 225 308 A Q H X S+ 0 0 30 -4,-1.6 4,-2.1 -5,-0.3 -1,-0.2 0.884 107.0 48.4 -66.6 -39.9 14.2 9.0 26.3 226 309 A V H X S+ 0 0 0 -4,-1.7 4,-2.4 2,-0.2 -1,-0.2 0.908 113.0 49.1 -63.6 -41.4 14.0 10.1 22.6 227 310 A L H X S+ 0 0 1 -4,-1.9 4,-2.4 2,-0.2 5,-0.2 0.855 109.7 50.5 -67.3 -42.5 17.8 10.4 22.5 228 311 A Q H X S+ 0 0 33 -4,-2.6 4,-2.0 2,-0.2 -1,-0.2 0.905 115.3 43.2 -56.9 -47.5 18.4 7.0 24.0 229 312 A N H X S+ 0 0 0 -4,-2.1 4,-2.4 -5,-0.2 -2,-0.2 0.868 111.6 55.5 -70.7 -32.7 16.1 5.4 21.5 230 313 A M H X S+ 0 0 0 -4,-2.4 4,-2.7 2,-0.2 -2,-0.2 0.949 111.4 42.0 -61.1 -52.7 17.6 7.5 18.7 231 314 A V H X S+ 0 0 0 -4,-2.4 4,-2.9 1,-0.2 -1,-0.2 0.888 113.5 53.9 -64.6 -37.4 21.1 6.3 19.3 232 315 A H H X S+ 0 0 1 -4,-2.0 4,-1.5 2,-0.2 -1,-0.2 0.885 109.7 47.2 -61.4 -44.9 19.8 2.7 19.9 233 316 A C H < S+ 0 0 0 -4,-2.4 -2,-0.2 2,-0.2 -1,-0.2 0.910 111.3 52.1 -61.1 -45.7 18.0 2.8 16.5 234 317 A A H >< S+ 0 0 0 -4,-2.7 3,-1.2 1,-0.2 -2,-0.2 0.916 109.8 48.9 -56.4 -42.6 21.3 4.2 15.0 235 318 A D H 3< S+ 0 0 17 -4,-2.9 3,-0.3 1,-0.3 -1,-0.2 0.825 117.4 41.3 -62.8 -38.2 23.2 1.3 16.6 236 319 A L T 3< S+ 0 0 14 -4,-1.5 -1,-0.3 1,-0.2 -2,-0.2 -0.223 86.7 104.6-105.0 38.9 20.6 -1.2 15.2 237 320 A S X + 0 0 0 -3,-1.2 3,-1.2 1,-0.1 4,-0.2 0.388 42.9 99.1-100.3 0.1 20.3 0.5 11.8 238 321 A N G > S+ 0 0 14 -3,-0.3 3,-1.7 1,-0.3 -1,-0.1 0.931 83.2 50.4 -59.1 -46.7 22.4 -1.9 9.6 239 322 A P G 3 S+ 0 0 0 0, 0.0 -1,-0.3 0, 0.0 80,-0.3 0.580 106.1 57.6 -71.6 -6.5 19.2 -3.7 8.2 240 323 A T G < S+ 0 0 0 -3,-1.2 76,-0.2 79,-0.1 -2,-0.2 0.306 90.4 90.0 -99.1 2.4 17.6 -0.4 7.2 241 324 A K S < S- 0 0 2 -3,-1.7 78,-0.1 -4,-0.2 5,-0.1 -0.507 98.6 -66.7 -94.1 167.2 20.5 0.7 5.0 242 325 A P >> - 0 0 63 0, 0.0 4,-2.4 0, 0.0 3,-1.0 -0.268 56.6-109.9 -52.8 143.9 20.9 -0.0 1.2 243 326 A L H 3> S+ 0 0 36 1,-0.3 4,-3.1 2,-0.2 5,-0.2 0.794 115.6 57.4 -49.4 -40.1 21.3 -3.7 0.7 244 327 A Q H 3> S+ 0 0 114 2,-0.2 4,-0.9 1,-0.2 -1,-0.3 0.894 111.1 42.5 -70.9 -32.2 24.9 -3.5 -0.4 245 328 A L H X> S+ 0 0 13 -3,-1.0 4,-1.7 2,-0.2 3,-0.7 0.950 113.2 54.7 -64.7 -51.6 25.9 -1.7 2.9 246 329 A Y H 3X S+ 0 0 1 -4,-2.4 4,-2.5 1,-0.2 3,-0.5 0.913 105.1 52.4 -47.9 -50.3 23.7 -4.1 4.9 247 330 A R H 3X S+ 0 0 94 -4,-3.1 4,-2.0 1,-0.3 -1,-0.2 0.805 106.9 52.0 -61.5 -33.5 25.5 -7.2 3.5 248 331 A Q H S+ 0 0 1 -4,-2.7 5,-3.2 2,-0.2 -2,-0.2 0.940 111.6 50.3 -58.5 -45.0 35.0 -20.4 23.4 265 348 A R H ><5S+ 0 0 78 -4,-2.3 3,-2.0 1,-0.2 -2,-0.2 0.938 111.6 44.1 -61.2 -54.7 36.0 -23.6 21.5 266 349 A E H 3<5S+ 0 0 161 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.827 111.6 54.7 -65.6 -27.7 39.7 -23.6 22.3 267 350 A R T 3<5S- 0 0 147 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.350 117.8-117.2 -77.2 2.5 38.9 -22.7 26.0 268 351 A G T < 5 + 0 0 69 -3,-2.0 -3,-0.2 1,-0.2 2,-0.2 0.721 68.2 139.0 64.7 26.4 36.7 -25.8 26.0 269 352 A M < - 0 0 52 -5,-3.2 -1,-0.2 -6,-0.2 2,-0.2 -0.568 63.5 -89.2 -95.1 162.7 33.5 -23.8 26.6 270 353 A E - 0 0 182 -2,-0.2 2,-0.4 1,-0.1 -1,-0.1 -0.491 49.7-110.8 -60.4 137.5 30.0 -24.3 25.0 271 354 A I - 0 0 56 -2,-0.2 5,-0.1 1,-0.1 3,-0.1 -0.598 32.0-123.5 -78.1 127.1 29.7 -22.3 21.8 272 355 A S > - 0 0 34 -2,-0.4 3,-1.9 1,-0.1 4,-0.2 -0.277 42.7 -75.3 -67.6 158.5 27.3 -19.3 22.1 273 356 A P T 3 S+ 0 0 106 0, 0.0 -1,-0.1 0, 0.0 -12,-0.0 -0.253 117.5 7.8 -55.5 134.5 24.3 -19.0 19.7 274 357 A M T 3 S+ 0 0 98 5,-0.2 -13,-0.1 -3,-0.1 -16,-0.1 0.519 106.2 96.5 71.6 12.5 25.3 -17.8 16.2 275 358 A C < + 0 0 4 -3,-1.9 2,-0.8 -14,-0.1 -14,-0.2 0.319 52.6 99.0-112.0 6.0 29.0 -18.1 17.0 276 359 A D > - 0 0 38 3,-0.2 3,-2.4 -4,-0.2 -18,-0.1 -0.824 52.7-164.8-100.4 101.1 29.7 -21.5 15.6 277 360 A K T 3 S+ 0 0 95 -2,-0.8 3,-0.4 1,-0.3 -1,-0.2 0.767 91.1 54.4 -51.6 -29.1 31.3 -21.2 12.1 278 361 A H T 3 S+ 0 0 145 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.348 116.5 36.0 -86.9 2.6 30.5 -25.0 11.5 279 362 A N S < S+ 0 0 129 -3,-2.4 2,-0.3 -5,-0.0 -3,-0.2 -0.246 85.3 135.9-153.9 58.3 26.8 -24.6 12.3 280 363 A A - 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