==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-MAR-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 20-OCT-09 3KB9 . COMPND 2 MOLECULE: EPI-ISOZIZAENE SYNTHASE; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES COELICOLOR; . AUTHOR J.A.AARON,X.LIN,D.E.CANE,D.W.CHRISTIANSON . 340 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14339.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 272 80.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 9 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 39 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 211 62.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 0 1 0 0 2 1 1 1 0 1 0 0 0 0 0 0 0 0 0 1 1 1 0 2 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A A 0 0 138 0, 0.0 6,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 119.3 22.9 4.4 -36.8 2 17 A V - 0 0 7 1,-0.1 5,-0.2 2,-0.1 314,-0.0 -0.563 360.0 -97.8 -70.4 134.7 21.3 1.7 -34.7 3 18 A P >> - 0 0 60 0, 0.0 3,-2.3 0, 0.0 4,-1.3 -0.264 32.9-119.0 -51.7 138.6 23.9 -0.9 -33.8 4 19 A P T 34 S+ 0 0 97 0, 0.0 3,-0.4 0, 0.0 -2,-0.1 0.829 111.9 57.5 -53.0 -37.9 23.6 -3.9 -36.2 5 20 A S T 34 S+ 0 0 55 1,-0.2 257,-0.1 3,-0.0 -3,-0.0 0.654 118.1 34.1 -65.0 -15.9 22.7 -6.4 -33.4 6 21 A L T <4 S+ 0 0 27 -3,-2.3 -1,-0.2 222,-0.0 2,-0.1 0.499 90.9 115.6-116.2 -10.6 19.7 -4.2 -32.5 7 22 A R < - 0 0 91 -4,-1.3 308,-0.0 -3,-0.4 0, 0.0 -0.407 39.0-173.6 -72.4 136.8 18.7 -2.8 -35.8 8 23 A L >> - 0 0 2 -2,-0.1 4,-2.0 1,-0.1 3,-0.7 -0.848 4.8-171.6-129.1 93.5 15.3 -3.8 -37.2 9 24 A P H 3> S+ 0 0 78 0, 0.0 4,-2.5 0, 0.0 5,-0.3 0.800 85.1 61.1 -58.5 -29.9 14.9 -2.5 -40.8 10 25 A V H 3> S+ 0 0 69 2,-0.2 4,-2.7 1,-0.2 5,-0.3 0.899 106.4 44.8 -64.7 -41.5 11.2 -3.5 -40.9 11 26 A I H <> S+ 0 0 1 -3,-0.7 4,-1.5 1,-0.2 -1,-0.2 0.939 113.7 51.5 -64.0 -41.3 10.5 -1.1 -38.0 12 27 A E H < S+ 0 0 73 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.898 123.6 27.2 -65.0 -38.2 12.6 1.6 -39.6 13 28 A A H < S+ 0 0 87 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.870 129.7 34.1 -89.3 -41.6 10.8 1.3 -43.0 14 29 A A H < S+ 0 0 47 -4,-2.7 -3,-0.2 -5,-0.3 -2,-0.2 0.452 111.9 55.2-105.1 -5.3 7.3 0.0 -42.2 15 30 A F S < S- 0 0 2 -4,-1.5 -1,-0.2 -5,-0.3 -4,-0.0 -0.598 75.6-161.5-126.5 72.4 6.5 1.6 -38.8 16 31 A P - 0 0 83 0, 0.0 296,-0.1 0, 0.0 -3,-0.1 -0.268 26.1-106.1 -61.1 138.5 6.9 5.4 -39.3 17 32 A R - 0 0 106 -5,-0.2 2,-0.3 295,-0.1 292,-0.1 -0.284 31.6-160.4 -66.2 147.0 7.3 7.3 -36.1 18 33 A Q - 0 0 83 42,-0.3 2,-0.4 291,-0.2 45,-0.0 -0.951 2.6-162.8-123.0 145.9 4.5 9.5 -34.7 19 34 A L - 0 0 100 -2,-0.3 41,-0.2 41,-0.0 40,-0.1 -0.986 20.9-126.7-134.2 125.1 4.8 12.4 -32.2 20 35 A H > - 0 0 7 39,-2.1 3,-1.8 -2,-0.4 39,-0.1 -0.408 20.6-127.6 -66.4 140.8 1.9 13.8 -30.2 21 36 A P T 3 S+ 0 0 117 0, 0.0 4,-0.2 0, 0.0 -1,-0.1 0.676 106.1 64.0 -67.2 -17.1 1.7 17.6 -30.6 22 37 A Y T >> S+ 0 0 39 1,-0.2 4,-2.8 2,-0.1 3,-0.7 0.582 74.4 103.2 -77.7 -5.0 1.5 18.1 -26.8 23 38 A W H <> S+ 0 0 47 -3,-1.8 4,-2.8 1,-0.3 5,-0.2 0.834 73.4 52.2 -52.8 -45.8 5.1 16.6 -26.5 24 39 A P H 3> S+ 0 0 80 0, 0.0 4,-1.4 0, 0.0 -1,-0.3 0.923 116.3 40.6 -61.4 -39.8 7.0 19.9 -25.9 25 40 A K H <> S+ 0 0 128 -3,-0.7 4,-2.8 -4,-0.2 -2,-0.2 0.898 113.1 56.8 -67.4 -41.6 4.7 20.9 -23.1 26 41 A L H X S+ 0 0 0 -4,-2.8 4,-2.8 1,-0.2 5,-0.3 0.905 103.1 53.7 -54.2 -46.6 4.7 17.3 -21.8 27 42 A Q H X S+ 0 0 41 -4,-2.8 4,-1.7 1,-0.2 -1,-0.2 0.930 114.5 40.6 -55.8 -48.5 8.5 17.3 -21.5 28 43 A E H X S+ 0 0 92 -4,-1.4 4,-2.4 -5,-0.2 -1,-0.2 0.899 114.5 51.5 -67.6 -42.9 8.5 20.4 -19.4 29 44 A T H X S+ 0 0 41 -4,-2.8 4,-2.0 2,-0.2 -2,-0.2 0.905 111.1 46.1 -68.8 -39.6 5.5 19.4 -17.3 30 45 A T H X S+ 0 0 4 -4,-2.8 4,-2.5 2,-0.2 -1,-0.2 0.901 111.8 52.0 -70.2 -38.6 6.7 15.9 -16.3 31 46 A R H X S+ 0 0 38 -4,-1.7 4,-2.1 -5,-0.3 -2,-0.2 0.945 110.6 48.3 -57.2 -47.4 10.2 17.3 -15.5 32 47 A T H X S+ 0 0 57 -4,-2.4 4,-3.0 1,-0.2 -2,-0.2 0.875 111.2 51.6 -60.9 -38.7 8.5 19.9 -13.2 33 48 A W H X S+ 0 0 20 -4,-2.0 4,-2.9 2,-0.2 6,-0.3 0.906 105.4 53.5 -68.1 -42.1 6.4 17.1 -11.6 34 49 A L H <>S+ 0 0 7 -4,-2.5 5,-2.4 2,-0.2 6,-0.8 0.929 114.5 44.1 -57.4 -43.7 9.5 14.9 -10.9 35 50 A L H ><5S+ 0 0 67 -4,-2.1 3,-1.3 3,-0.2 -2,-0.2 0.955 113.6 48.3 -61.8 -53.9 11.0 18.0 -9.1 36 51 A E H 3<5S+ 0 0 148 -4,-3.0 -2,-0.2 1,-0.3 -1,-0.2 0.854 115.8 44.0 -60.1 -37.1 7.8 18.9 -7.3 37 52 A K T 3<5S- 0 0 53 -4,-2.9 -1,-0.3 -5,-0.2 -2,-0.2 0.466 107.5-128.2 -87.2 -1.0 7.2 15.4 -6.1 38 53 A R T < 5 + 0 0 175 -3,-1.3 -3,-0.2 -4,-0.3 84,-0.1 0.862 59.5 145.5 57.4 41.2 10.9 15.0 -5.2 39 54 A L S > - 0 0 57 0, 0.0 4,-2.4 0, 0.0 3,-0.5 -0.284 39.2-114.7 -58.6 148.3 17.2 15.0 -6.7 42 57 A A H 3> S+ 0 0 70 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.869 114.3 50.2 -53.6 -43.9 17.2 18.5 -8.4 43 58 A D H 3> S+ 0 0 109 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.811 112.4 47.4 -68.3 -30.0 20.7 18.2 -9.8 44 59 A K H <>>S+ 0 0 46 -3,-0.5 4,-2.7 2,-0.2 5,-0.7 0.846 110.1 52.0 -80.8 -33.8 19.9 14.8 -11.4 45 60 A V H X>S+ 0 0 2 -4,-2.4 4,-1.5 3,-0.2 5,-0.5 0.955 113.0 46.6 -59.8 -47.0 16.7 16.1 -12.8 46 61 A E H <5S+ 0 0 156 -4,-2.6 -2,-0.2 -5,-0.2 -1,-0.2 0.907 120.8 36.3 -61.7 -43.0 18.6 19.0 -14.4 47 62 A E H <5S+ 0 0 130 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.861 135.0 13.2 -78.0 -35.8 21.4 16.8 -15.7 48 63 A Y H X5S+ 0 0 58 -4,-2.7 4,-1.2 -5,-0.1 -3,-0.2 0.703 94.6 87.1-120.4 -26.8 19.4 13.7 -16.7 49 64 A A H >X4 S+ 0 0 12 -5,-0.5 4,-1.5 1,-0.2 5,-0.1 0.884 74.0 46.1 -66.2 -36.8 10.4 9.1 -20.8 55 70 A T H > S+ 0 0 10 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.897 109.5 55.1 -71.2 -35.7 7.9 11.7 -22.1 56 71 A D H > S+ 0 0 32 1,-0.2 4,-1.3 2,-0.2 -2,-0.2 0.909 104.4 55.6 -61.1 -41.8 9.0 11.1 -25.7 57 72 A L H < S+ 0 0 10 -4,-2.1 3,-0.4 1,-0.2 -1,-0.2 0.932 112.7 40.1 -56.8 -47.7 8.3 7.4 -25.3 58 73 A M H >X S+ 0 0 1 -4,-1.5 4,-2.1 1,-0.2 3,-1.5 0.879 111.4 56.1 -74.3 -33.5 4.7 8.0 -24.2 59 74 A A H 3< S+ 0 0 0 -4,-2.7 -39,-2.1 1,-0.3 -1,-0.2 0.653 106.0 53.0 -71.6 -16.9 4.1 10.8 -26.7 60 75 A G T 3< S+ 0 0 4 -4,-1.3 253,-0.3 -3,-0.4 -42,-0.3 0.405 116.7 40.3 -88.2 -2.3 5.1 8.4 -29.5 61 76 A Y T <4 S+ 0 0 0 -3,-1.5 2,-1.9 -5,-0.1 248,-0.2 0.803 105.7 50.7-109.7 -63.5 2.6 5.9 -28.2 62 77 A Y S >< S+ 0 0 0 -4,-2.1 3,-1.8 247,-0.1 -1,-0.1 -0.356 71.9 178.4 -88.0 61.5 -0.7 7.3 -27.1 63 78 A L T 3 + 0 0 35 -2,-1.9 243,-0.1 1,-0.3 -3,-0.1 -0.294 66.5 25.0 -60.9 144.6 -1.4 9.4 -30.2 64 79 A G T 3 S+ 0 0 66 1,-0.3 -1,-0.3 242,-0.0 3,-0.1 0.353 86.1 144.5 82.6 -9.2 -4.8 11.2 -30.0 65 80 A A < - 0 0 4 -3,-1.8 -1,-0.3 1,-0.1 130,-0.1 -0.354 60.4-103.9 -60.3 142.7 -4.8 11.3 -26.2 66 81 A P >> - 0 0 66 0, 0.0 4,-2.7 0, 0.0 3,-0.6 -0.400 35.1-113.5 -57.4 146.8 -6.3 14.3 -24.6 67 82 A D H 3> S+ 0 0 84 1,-0.3 4,-2.4 2,-0.2 5,-0.1 0.872 116.6 51.1 -51.4 -46.7 -3.5 16.5 -23.3 68 83 A E H 3> S+ 0 0 146 2,-0.2 4,-1.7 1,-0.2 -1,-0.3 0.835 110.9 48.7 -62.8 -34.9 -4.5 15.9 -19.7 69 84 A V H <> S+ 0 0 6 -3,-0.6 4,-2.6 2,-0.2 -2,-0.2 0.918 110.4 50.0 -70.4 -45.8 -4.6 12.2 -20.2 70 85 A L H X S+ 0 0 0 -4,-2.7 4,-2.9 1,-0.2 -2,-0.2 0.894 109.4 53.2 -60.0 -38.7 -1.2 12.1 -21.8 71 86 A Q H X S+ 0 0 11 -4,-2.4 4,-2.4 -5,-0.2 -1,-0.2 0.916 109.8 46.3 -61.6 -42.5 0.1 14.2 -18.9 72 87 A A H X S+ 0 0 0 -4,-1.7 4,-2.6 1,-0.2 -2,-0.2 0.904 114.5 48.8 -66.9 -42.5 -1.2 11.7 -16.3 73 88 A I H X S+ 0 0 0 -4,-2.6 4,-2.7 2,-0.2 -2,-0.2 0.921 112.0 48.0 -61.4 -43.3 0.2 8.8 -18.3 74 89 A A H X S+ 0 0 1 -4,-2.9 4,-2.6 2,-0.2 -2,-0.2 0.903 112.8 47.2 -68.9 -37.5 3.6 10.4 -18.7 75 90 A D H X S+ 0 0 2 -4,-2.4 4,-2.8 2,-0.2 -1,-0.2 0.939 113.4 48.6 -68.2 -44.1 3.9 11.3 -15.0 76 91 A Y H X S+ 0 0 0 -4,-2.6 4,-2.3 -5,-0.2 -2,-0.2 0.910 112.7 49.5 -60.0 -41.4 2.8 7.7 -14.1 77 92 A S H X S+ 0 0 0 -4,-2.7 4,-2.1 2,-0.2 -2,-0.2 0.904 110.2 48.6 -67.0 -43.7 5.4 6.3 -16.6 78 93 A A H X S+ 0 0 1 -4,-2.6 4,-2.2 1,-0.2 5,-0.2 0.942 111.9 50.8 -59.9 -44.1 8.2 8.4 -15.3 79 94 A W H X S+ 0 0 0 -4,-2.8 4,-2.6 1,-0.2 -2,-0.2 0.906 106.9 55.1 -52.2 -46.6 7.2 7.3 -11.8 80 95 A F H X S+ 0 0 14 -4,-2.3 4,-2.4 1,-0.2 -1,-0.2 0.892 106.9 49.6 -62.8 -40.9 7.3 3.7 -13.0 81 96 A F H X S+ 0 0 34 -4,-2.1 4,-2.1 2,-0.2 -1,-0.2 0.931 111.1 48.5 -60.9 -44.4 10.9 4.1 -14.2 82 97 A V H X S+ 0 0 17 -4,-2.2 4,-2.5 1,-0.2 -2,-0.2 0.869 110.0 53.4 -65.5 -35.0 11.9 5.6 -10.9 83 98 A W H X S+ 0 0 0 -4,-2.6 4,-2.9 2,-0.2 5,-0.2 0.910 105.9 52.1 -64.4 -42.8 10.1 2.7 -9.1 84 99 A D H X S+ 0 0 36 -4,-2.4 4,-2.2 1,-0.2 -2,-0.2 0.910 111.7 48.4 -56.3 -41.0 12.1 0.2 -11.3 85 100 A D H X S+ 0 0 16 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.905 111.4 48.4 -65.6 -42.3 15.2 2.1 -10.1 86 101 A R H X S+ 0 0 68 -4,-2.5 4,-2.8 2,-0.2 5,-0.2 0.919 111.9 49.5 -65.0 -45.6 14.1 2.0 -6.4 87 102 A H H X S+ 0 0 1 -4,-2.9 4,-2.1 1,-0.2 -1,-0.2 0.923 111.0 50.2 -56.4 -45.8 13.4 -1.8 -6.6 88 103 A D H X S+ 0 0 27 -4,-2.2 4,-2.7 -5,-0.2 -2,-0.2 0.919 112.2 46.6 -61.0 -46.7 16.7 -2.4 -8.2 89 104 A R H X S+ 0 0 7 -4,-2.3 4,-2.5 1,-0.2 6,-0.2 0.878 109.2 54.2 -67.3 -37.3 18.5 -0.4 -5.4 90 105 A D H <>S+ 0 0 2 -4,-2.8 5,-2.6 2,-0.2 4,-0.4 0.887 112.2 45.3 -63.2 -39.2 16.6 -2.1 -2.7 91 106 A I H ><5S+ 0 0 18 -4,-2.1 3,-1.4 -5,-0.2 -2,-0.2 0.959 113.0 49.0 -67.5 -48.4 17.7 -5.5 -4.1 92 107 A V H 3<5S+ 0 0 70 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.882 117.4 42.0 -60.6 -37.4 21.3 -4.4 -4.6 93 108 A H T 3<5S- 0 0 85 -4,-2.5 -1,-0.3 -5,-0.2 -2,-0.2 0.376 110.3-119.4 -92.1 4.5 21.5 -3.1 -1.0 94 109 A G T < 5 + 0 0 56 -3,-1.4 2,-1.8 -4,-0.4 3,-0.3 0.798 53.9 158.7 66.8 30.2 19.6 -5.9 0.6 95 110 A R >< + 0 0 91 -5,-2.6 4,-2.3 -6,-0.2 5,-0.2 -0.437 3.0 155.5 -88.7 67.2 16.8 -3.8 1.9 96 111 A A H > S+ 0 0 52 -2,-1.8 4,-2.4 1,-0.2 -1,-0.2 0.867 71.6 48.7 -62.1 -40.1 14.2 -6.5 2.3 97 112 A G H > S+ 0 0 19 -3,-0.3 4,-2.5 2,-0.2 -1,-0.2 0.928 110.9 48.3 -66.4 -46.7 12.2 -4.7 4.9 98 113 A A H > S+ 0 0 34 1,-0.2 4,-2.2 2,-0.2 -2,-0.2 0.894 113.4 48.8 -63.5 -37.7 12.0 -1.4 3.0 99 114 A W H X S+ 0 0 2 -4,-2.3 4,-3.0 2,-0.2 5,-0.2 0.935 110.0 50.6 -67.7 -44.9 10.9 -3.3 -0.1 100 115 A R H X S+ 0 0 138 -4,-2.4 4,-2.1 -5,-0.2 -2,-0.2 0.928 112.7 47.4 -58.4 -39.0 8.2 -5.3 1.7 101 116 A R H X S+ 0 0 153 -4,-2.5 4,-2.3 2,-0.2 -1,-0.2 0.910 112.2 48.0 -70.5 -41.4 6.9 -2.1 3.2 102 117 A L H X S+ 0 0 3 -4,-2.2 4,-2.8 2,-0.2 5,-0.2 0.921 109.6 54.5 -61.9 -46.2 6.9 -0.2 -0.1 103 118 A R H X S+ 0 0 59 -4,-3.0 4,-1.9 1,-0.2 -2,-0.2 0.931 110.9 45.5 -53.0 -47.0 5.1 -3.2 -1.8 104 119 A G H X S+ 0 0 33 -4,-2.1 4,-2.0 -5,-0.2 -1,-0.2 0.901 111.8 51.2 -67.3 -39.2 2.4 -3.1 0.9 105 120 A L H X S+ 0 0 50 -4,-2.3 4,-3.0 2,-0.2 5,-0.2 0.875 108.1 52.1 -65.5 -36.4 2.0 0.7 0.6 106 121 A L H X S+ 0 0 0 -4,-2.8 4,-2.5 2,-0.2 5,-0.2 0.917 108.2 51.1 -68.3 -40.1 1.6 0.6 -3.2 107 122 A H H X S+ 0 0 38 -4,-1.9 4,-1.1 -5,-0.2 -2,-0.2 0.944 115.5 42.5 -60.1 -46.2 -1.1 -2.1 -2.9 108 123 A T H X S+ 0 0 74 -4,-2.0 4,-1.8 2,-0.2 3,-0.3 0.920 115.6 48.2 -65.3 -44.9 -3.0 0.1 -0.4 109 124 A A H < S+ 0 0 0 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.868 103.6 61.3 -64.3 -36.2 -2.4 3.4 -2.4 110 125 A L H < S+ 0 0 0 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.904 111.5 39.8 -61.1 -35.2 -3.5 1.8 -5.6 111 126 A D H < S+ 0 0 102 -4,-1.1 -1,-0.2 -3,-0.3 -2,-0.2 0.816 132.8 22.7 -83.7 -27.8 -6.9 1.2 -4.0 112 127 A S S < S+ 0 0 34 -4,-1.8 3,-0.5 1,-0.1 4,-0.3 -0.640 70.6 161.1-134.9 74.5 -7.1 4.5 -2.2 113 128 A P > + 0 0 10 0, 0.0 3,-2.5 0, 0.0 4,-0.3 0.910 68.4 59.8 -74.8 -38.2 -4.9 7.0 -3.9 114 129 A G G > S+ 0 0 36 1,-0.3 3,-1.1 2,-0.2 4,-0.1 0.826 99.7 61.6 -54.3 -30.9 -6.2 10.3 -2.6 115 130 A D G 3 S+ 0 0 137 -3,-0.5 -1,-0.3 1,-0.2 3,-0.2 0.618 107.0 44.8 -66.9 -14.4 -5.5 9.1 0.9 116 131 A H G X S+ 0 0 23 -3,-2.5 3,-1.8 -4,-0.3 12,-0.3 0.251 72.6 113.7-116.8 10.6 -1.8 8.9 0.1 117 132 A L T < S+ 0 0 38 -3,-1.1 -1,-0.1 1,-0.3 12,-0.1 0.681 90.2 32.2 -61.1 -20.7 -1.1 12.2 -1.8 118 133 A H T 3 S+ 0 0 173 -3,-0.2 -1,-0.3 -4,-0.1 4,-0.1 -0.053 84.7 153.6-127.4 32.6 1.2 13.5 1.0 119 134 A H < - 0 0 45 -3,-1.8 6,-0.2 2,-0.1 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