==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 14-NOV-01 1KE2 . COMPND 2 MOLECULE: SERINE-CARBOXYL PROTEINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: PSEUDOMONAS SP.; . AUTHOR A.WLODAWER,M.LI,A.GUSTCHINA,Z.DAUTER,K.UCHIDA,H.OYAMA,N.E.GO . 370 2 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12769.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 267 72.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 42 11.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 34 9.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 30 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 41 11.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 91 24.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 0 0 0 1 1 0 2 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 0 2 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 3 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 3 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A T 0 0 102 0, 0.0 204,-2.2 0, 0.0 2,-0.7 0.000 360.0 360.0 360.0 139.6 34.9 11.7 35.8 2 5 A A + 0 0 53 202,-0.2 2,-0.3 200,-0.0 202,-0.1 -0.858 360.0 131.8 -93.9 113.0 32.5 11.2 32.9 3 6 A K - 0 0 73 -2,-0.7 200,-0.1 200,-0.5 2,-0.1 -0.966 56.5 -84.9-152.6 168.7 29.8 14.0 32.7 4 7 A G - 0 0 14 -2,-0.3 2,-0.3 263,-0.1 265,-0.2 -0.359 43.4-153.4 -69.6 158.6 28.1 16.5 30.4 5 8 A H B -a 269 0A 0 263,-2.1 265,-2.6 -2,-0.1 5,-0.0 -0.999 18.5-117.4-140.6 140.1 29.7 19.9 29.8 6 9 A N > - 0 0 65 -2,-0.3 3,-2.8 263,-0.2 4,-0.4 -0.595 33.7-121.8 -61.7 133.4 28.6 23.4 28.9 7 10 A P G > S+ 0 0 3 0, 0.0 3,-1.5 0, 0.0 -1,-0.1 0.816 112.0 70.2 -45.5 -35.6 30.2 24.3 25.5 8 11 A T G 3 S+ 0 0 48 1,-0.2 4,-0.4 2,-0.1 76,-0.0 0.741 90.4 61.6 -61.5 -13.0 31.7 27.2 27.4 9 12 A E G <> S+ 0 0 55 -3,-2.8 4,-2.3 1,-0.2 3,-0.5 0.734 78.1 85.1 -85.9 -18.4 34.0 24.7 29.2 10 13 A F H <> S+ 0 0 0 -3,-1.5 4,-2.7 -4,-0.4 6,-0.2 0.857 82.7 59.6 -56.2 -37.5 35.8 23.4 26.1 11 14 A P H 4>S+ 0 0 8 0, 0.0 5,-3.6 0, 0.0 6,-0.6 0.947 110.7 41.2 -55.2 -46.2 38.5 26.2 26.1 12 15 A T H >45S+ 0 0 76 -3,-0.5 3,-0.8 -4,-0.4 199,-0.4 0.881 114.6 51.9 -73.0 -30.3 39.6 25.2 29.6 13 16 A I H 3<5S+ 0 0 3 -4,-2.3 -1,-0.2 1,-0.2 -3,-0.2 0.920 118.2 37.0 -67.8 -34.9 39.4 21.5 28.9 14 17 A Y T 3<5S- 0 0 0 -4,-2.7 341,-2.2 -5,-0.2 342,-0.3 0.169 116.9-109.1-107.4 21.7 41.5 21.8 25.7 15 18 A D T < 5S+ 0 0 60 -3,-0.8 341,-1.7 339,-0.2 -3,-0.2 0.835 79.1 125.7 63.0 43.9 43.9 24.5 27.1 16 19 A A > < + 0 0 0 -5,-3.6 3,-1.3 -6,-0.2 -4,-0.2 0.297 33.5 100.6-113.2 6.4 42.6 27.5 25.0 17 20 A S T 3 S+ 0 0 72 -6,-0.6 -1,-0.1 1,-0.3 -5,-0.1 0.834 81.4 55.3 -62.8 -32.1 41.8 30.0 27.7 18 21 A S T 3 S+ 0 0 113 -7,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.528 95.5 84.1 -79.3 -8.9 45.0 31.9 27.1 19 22 A A S < S- 0 0 14 -3,-1.3 278,-0.1 1,-0.1 337,-0.1 -0.541 89.5 -96.2 -91.6 161.4 44.3 32.4 23.4 20 23 A P - 0 0 64 0, 0.0 280,-0.2 0, 0.0 -1,-0.1 -0.289 41.6-106.9 -68.9 160.2 42.1 35.1 21.8 21 24 A T - 0 0 47 69,-0.1 3,-0.4 278,-0.1 69,-0.2 -0.263 35.0-102.0 -72.8 179.1 38.5 34.4 21.1 22 25 A A E > S+c 93 0B 0 70,-1.3 3,-2.6 67,-1.0 72,-1.3 0.065 79.6 127.9 -88.8 21.6 37.5 34.0 17.4 23 26 A A E 3 S+ 0 0 42 70,-0.3 -1,-0.2 1,-0.3 70,-0.2 0.745 75.2 44.4 -53.6 -23.8 36.1 37.5 17.4 24 27 A N E 3 S+ 0 0 104 -3,-0.4 2,-0.4 68,-0.2 -1,-0.3 0.333 101.0 80.6-107.1 13.4 38.1 38.3 14.2 25 28 A T E < - 0 0 0 -3,-2.6 69,-2.3 99,-0.0 70,-0.7 -0.950 68.1-142.5-118.7 134.5 37.3 35.1 12.4 26 29 A T E -c 95 0B 12 -2,-0.4 99,-2.1 97,-0.3 100,-1.0 -0.810 21.9-164.3 -90.7 132.8 34.2 34.4 10.4 27 30 A V E -cd 96 126B 0 68,-2.5 70,-2.8 -2,-0.4 2,-0.3 -0.933 4.7-152.8-126.0 146.9 33.0 30.8 10.6 28 31 A G E -cd 97 127B 0 98,-2.6 100,-3.3 -2,-0.4 2,-0.4 -0.809 3.1-161.7-113.1 150.6 30.5 28.8 8.5 29 32 A I E -cd 98 128B 0 68,-2.5 70,-2.3 -2,-0.3 2,-0.5 -0.998 15.9-138.0-132.5 128.4 28.2 25.9 9.3 30 33 A I E +c 99 0B 0 98,-2.6 100,-0.4 -2,-0.4 2,-0.3 -0.737 30.9 174.3 -86.3 128.0 26.7 23.7 6.6 31 34 A T E -c 100 0B 0 68,-2.6 70,-2.7 -2,-0.5 2,-0.6 -0.860 33.8-127.0-127.0 168.9 23.1 22.8 7.2 32 35 A I E S-c 101 0B 42 -2,-0.3 39,-0.3 68,-0.2 70,-0.1 -0.948 80.5 -20.9-110.0 109.1 20.2 20.9 5.5 33 36 A G S S- 0 0 0 68,-1.9 37,-0.2 -2,-0.6 68,-0.2 -0.396 105.0 -21.9 86.2-168.5 17.2 23.2 5.5 34 37 A G B -j 70 0C 2 35,-2.6 37,-0.6 -2,-0.1 -2,-0.1 -0.125 36.0-154.5 -82.0 174.9 16.4 26.2 7.7 35 38 A V > + 0 0 4 33,-0.2 4,-2.5 35,-0.1 5,-0.2 -0.001 48.4 126.4-138.1 25.4 17.6 27.3 11.1 36 39 A S H > S+ 0 0 81 2,-0.2 4,-1.4 1,-0.2 3,-0.2 0.950 83.9 40.3 -54.6 -54.8 14.9 29.5 12.6 37 40 A Q H >> S+ 0 0 47 1,-0.2 4,-2.8 2,-0.2 3,-0.7 0.948 112.2 58.6 -60.9 -46.8 14.6 27.5 15.8 38 41 A T H 3> S+ 0 0 0 1,-0.3 4,-2.3 2,-0.2 -1,-0.2 0.877 103.6 51.2 -45.2 -45.8 18.4 27.1 16.0 39 42 A L H 3X S+ 0 0 43 -4,-2.5 4,-1.6 1,-0.2 -1,-0.3 0.874 110.7 48.9 -67.8 -32.4 18.8 30.9 16.0 40 43 A Q H S+ 0 0 2 -4,-2.7 5,-3.3 1,-0.2 4,-0.2 0.955 117.6 50.5 -63.4 -43.1 24.5 33.4 24.6 47 50 A S H ><5S+ 0 0 70 -4,-2.4 3,-1.6 -5,-0.2 -2,-0.2 0.932 109.9 47.5 -56.8 -51.9 22.0 35.0 26.9 48 51 A A H 3<5S+ 0 0 60 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.901 113.9 48.0 -60.9 -36.9 22.1 32.3 29.6 49 52 A N T 3<5S- 0 0 48 -4,-2.0 -1,-0.3 -5,-0.3 -2,-0.2 0.477 112.9-120.6 -86.1 6.5 25.9 32.4 29.5 50 53 A G T < 5 + 0 0 67 -3,-1.6 2,-0.2 -4,-0.2 -3,-0.2 0.864 62.9 148.2 64.4 28.6 25.9 36.1 29.7 51 54 A L < - 0 0 53 -5,-3.3 -1,-0.2 -6,-0.2 2,-0.2 -0.639 57.1 -94.7 -95.8 157.5 27.8 36.4 26.5 52 55 A A - 0 0 82 -2,-0.2 -1,-0.1 39,-0.2 -3,-0.0 -0.499 55.7 -97.0 -62.2 136.4 27.6 39.1 23.8 53 56 A S - 0 0 87 -2,-0.2 2,-0.5 1,-0.1 -1,-0.1 -0.087 38.7-114.9 -52.7 150.3 25.1 38.1 21.1 54 57 A V - 0 0 20 -3,-0.1 2,-0.7 -12,-0.1 -1,-0.1 -0.806 17.0-127.4 -97.5 130.8 26.4 36.4 18.0 55 58 A N - 0 0 97 -2,-0.5 41,-2.8 38,-0.4 2,-0.3 -0.624 39.3-176.6 -71.7 114.6 26.2 38.1 14.6 56 59 A T E -e 96 0B 41 -2,-0.7 2,-0.3 39,-0.2 41,-0.2 -0.799 19.1-169.9-113.4 154.3 24.6 35.5 12.3 57 60 A Q E -e 97 0B 95 39,-2.4 41,-2.9 -2,-0.3 2,-0.4 -0.994 11.1-150.6-134.8 147.0 23.7 35.3 8.6 58 61 A T E -e 98 0B 70 -2,-0.3 2,-0.5 39,-0.2 41,-0.2 -0.959 12.9-160.3-113.8 133.4 21.6 32.7 6.9 59 62 A I E -e 99 0B 33 39,-3.3 41,-2.3 -2,-0.4 2,-1.0 -0.960 16.9-144.8-123.2 127.3 22.3 31.9 3.2 60 63 A Q E -e 100 0B 110 -2,-0.5 41,-0.1 1,-0.2 39,-0.1 -0.779 23.2-173.5 -82.6 98.5 19.9 30.1 0.8 61 64 A T + 0 0 9 39,-1.9 -1,-0.2 -2,-1.0 40,-0.1 0.674 59.6 29.0 -78.2 -21.3 22.6 28.2 -1.1 62 65 A G S S- 0 0 24 38,-0.4 2,-0.1 1,-0.3 -2,-0.1 0.143 110.5 -1.3-111.3-134.8 20.4 26.8 -4.0 63 66 A S > - 0 0 76 1,-0.1 3,-2.4 2,-0.1 -1,-0.3 -0.345 56.4-131.0 -63.4 136.4 17.3 27.8 -5.8 64 67 A S T 3 S+ 0 0 72 1,-0.3 -1,-0.1 -3,-0.1 -3,-0.0 0.603 113.7 42.8 -59.1 -18.7 15.5 31.0 -4.7 65 68 A N T 3 S+ 0 0 72 2,-0.0 -1,-0.3 3,-0.0 -2,-0.1 -0.046 93.5 118.8-114.2 23.2 12.3 29.0 -4.6 66 69 A G S < S- 0 0 16 -3,-2.4 2,-1.0 1,-0.1 36,-0.0 -0.261 76.0 -85.8 -85.3 178.7 13.8 25.9 -2.9 67 70 A D + 0 0 65 1,-0.1 36,-2.2 -2,-0.0 38,-0.1 -0.689 53.0 154.2 -91.8 99.9 12.9 24.4 0.4 68 71 A Y + 0 0 23 -2,-1.0 -33,-0.2 34,-0.2 -1,-0.1 0.025 29.0 135.4-110.9 27.5 14.7 26.1 3.3 69 72 A S - 0 0 61 -36,-0.1 -35,-2.6 1,-0.1 2,-0.1 -0.306 65.4 -86.2 -65.1 157.2 12.1 25.3 5.9 70 73 A D B -j 34 0C 53 -37,-0.2 2,-0.6 1,-0.0 -35,-0.1 -0.425 27.9-146.8 -66.0 140.1 13.3 24.0 9.3 71 74 A D > - 0 0 66 -37,-0.6 4,-2.0 -39,-0.3 -39,-0.1 -0.932 14.4-147.7 -96.6 120.8 13.9 20.3 9.8 72 75 A Q H >> S+ 0 0 133 -2,-0.6 4,-0.9 1,-0.2 3,-0.6 0.970 98.0 41.3 -63.2 -51.5 13.0 19.8 13.4 73 76 A Q H >> S+ 0 0 159 1,-0.2 4,-1.0 2,-0.2 3,-0.6 0.890 110.6 61.5 -59.3 -35.9 15.5 17.0 14.1 74 77 A G H >> S+ 0 0 0 1,-0.2 4,-2.2 2,-0.2 3,-0.6 0.869 91.5 66.2 -56.4 -37.6 17.9 19.1 12.0 75 78 A Q H S+ 0 0 0 -4,-2.6 5,-2.5 -5,-0.2 6,-0.3 0.928 115.3 48.9 -65.8 -40.2 30.8 29.5 20.0 87 90 A G H ><5S+ 0 0 1 -4,-2.8 3,-1.6 -5,-0.3 -1,-0.2 0.969 115.5 44.5 -60.0 -47.1 31.6 27.9 23.4 88 91 A S H 3<5S+ 0 0 0 -4,-2.9 -2,-0.2 1,-0.3 -1,-0.2 0.859 104.6 62.5 -68.9 -30.6 34.9 26.6 22.0 89 92 A A T 3<5S- 0 0 0 -4,-2.8 -67,-1.0 -5,-0.3 -1,-0.3 0.525 125.0-101.4 -67.1 -4.3 35.7 29.9 20.3 90 93 A G T < 5S- 0 0 33 -3,-1.6 -3,-0.2 -4,-0.3 -2,-0.2 0.607 73.2 -56.6 87.8 15.4 35.7 31.4 23.8 91 94 A G S S- 0 0 91 2,-0.1 3,-2.1 3,-0.1 4,-0.4 -0.503 74.0 -13.1 -89.7 164.9 17.5 16.2 -6.3 107 110 A G T 3 S- 0 0 69 1,-0.3 3,-0.4 2,-0.1 4,-0.2 -0.041 123.7 -38.4 43.9-139.2 20.2 13.6 -5.3 108 111 A N T 3> S+ 0 0 32 1,-0.2 4,-2.5 33,-0.1 -1,-0.3 0.180 107.5 114.0 -96.5 20.7 22.8 15.2 -3.1 109 112 A T H <> + 0 0 54 -3,-2.1 4,-2.6 1,-0.2 -1,-0.2 0.771 68.3 57.2 -68.6 -26.0 22.7 18.4 -5.2 110 113 A G H > S+ 0 0 4 -3,-0.4 4,-1.7 -4,-0.4 -8,-0.3 0.972 111.3 42.3 -68.6 -47.6 21.4 20.6 -2.4 111 114 A L H > S+ 0 0 13 1,-0.2 4,-2.5 2,-0.2 5,-0.3 0.938 113.7 53.3 -61.2 -42.5 24.2 19.7 -0.1 112 115 A T H X S+ 0 0 24 -4,-2.5 4,-2.6 1,-0.3 -1,-0.2 0.953 107.1 50.1 -59.3 -47.1 26.7 20.0 -2.9 113 116 A Q H X S+ 0 0 71 -4,-2.6 4,-2.3 1,-0.2 -1,-0.3 0.837 108.5 55.8 -59.6 -30.9 25.5 23.5 -3.8 114 117 A A H X S+ 0 0 0 -4,-1.7 4,-1.9 2,-0.2 -2,-0.2 0.935 108.5 44.5 -70.9 -42.2 25.8 24.4 -0.1 115 118 A F H X S+ 0 0 0 -4,-2.5 4,-2.1 1,-0.2 5,-0.2 0.943 113.9 54.0 -60.4 -40.7 29.5 23.4 0.0 116 119 A N H X S+ 0 0 76 -4,-2.6 4,-3.6 -5,-0.3 -2,-0.2 0.890 106.9 48.4 -62.9 -39.7 29.9 25.2 -3.3 117 120 A Q H X S+ 0 0 56 -4,-2.3 4,-3.4 2,-0.2 5,-0.3 0.916 109.7 51.6 -68.3 -43.2 28.4 28.6 -2.0 118 121 A A H X S+ 0 0 0 -4,-1.9 4,-1.3 2,-0.2 5,-0.4 0.912 116.7 42.3 -58.5 -37.9 30.5 28.6 1.1 119 122 A V H < S+ 0 0 5 -4,-2.1 -2,-0.2 -5,-0.2 -1,-0.2 0.941 114.7 49.1 -73.0 -47.8 33.5 28.0 -1.2 120 123 A S H < S+ 0 0 82 -4,-3.6 -2,-0.2 1,-0.2 -3,-0.2 0.935 111.8 48.4 -61.5 -43.6 32.4 30.5 -3.9 121 124 A D H < S- 0 0 56 -4,-3.4 -1,-0.2 -5,-0.2 -2,-0.2 0.876 85.8-165.6 -62.2 -35.6 31.7 33.3 -1.3 122 125 A N < + 0 0 79 -4,-1.3 -3,-0.1 -5,-0.3 -4,-0.1 0.860 51.7 112.2 52.5 38.7 35.1 32.7 0.3 123 126 A V + 0 0 80 -5,-0.4 2,-0.5 1,-0.1 -97,-0.3 0.747 52.9 77.5-111.0 -26.5 34.3 34.7 3.4 124 127 A A - 0 0 0 -6,-0.4 -97,-0.2 1,-0.2 3,-0.1 -0.659 60.7-163.6 -76.4 125.6 34.1 31.9 6.1 125 128 A K S S+ 0 0 41 -99,-2.1 35,-2.6 -2,-0.5 2,-0.4 0.859 79.5 25.4 -73.0 -33.6 37.7 31.0 7.1 126 129 A V E S-df 27 160B 0 -100,-1.0 -98,-2.6 33,-0.2 2,-0.4 -0.994 71.9-164.0-134.1 136.7 36.6 27.7 8.7 127 130 A I E -df 28 161B 0 33,-2.5 35,-2.7 -2,-0.4 2,-0.3 -0.991 11.4-140.6-129.1 124.3 33.4 25.7 7.9 128 131 A N E -df 29 162B 0 -100,-3.3 -98,-2.6 -2,-0.4 2,-0.4 -0.612 15.1-177.0 -85.5 136.8 31.8 23.0 10.1 129 132 A V E + f 0 163B 1 33,-2.3 35,-2.2 -2,-0.3 2,-0.9 -0.792 8.0 172.6-131.3 92.9 30.3 19.9 8.5 130 133 A S + 0 0 0 -2,-0.4 241,-3.0 -100,-0.4 2,-0.3 -0.290 55.9 83.7 -94.1 53.5 28.7 17.6 11.1 131 134 A L B +K 370 0D 0 -2,-0.9 2,-0.3 239,-0.3 239,-0.2 -0.953 44.1 139.2-145.4 164.2 27.2 15.3 8.5 132 135 A G - 0 0 0 237,-2.8 2,-0.3 -2,-0.3 33,-0.1 -0.947 19.0-162.0 174.4 174.9 28.2 12.3 6.4 133 136 A W E -L 188 0E 15 55,-1.9 55,-3.2 -2,-0.3 40,-0.1 -0.943 53.5 -42.3-165.1 173.4 27.3 8.9 4.9 134 137 A a E >> -L 187 0E 7 38,-0.4 4,-2.1 -2,-0.3 3,-0.9 -0.166 46.9-145.0 -46.4 116.0 28.9 5.8 3.4 135 138 A E H 3> S+ 0 0 4 51,-2.4 4,-3.0 1,-0.2 9,-0.2 0.845 98.2 60.0 -56.3 -32.2 31.7 7.0 1.0 136 139 A A H 3> S+ 0 0 34 50,-0.3 4,-2.6 1,-0.2 -1,-0.2 0.866 105.7 48.0 -66.5 -33.2 30.9 4.1 -1.4 137 140 A D H <> S+ 0 0 92 -3,-0.9 4,-1.3 2,-0.2 6,-0.3 0.899 111.2 49.6 -70.4 -43.9 27.4 5.4 -1.8 138 141 A A H <>S+ 0 0 0 -4,-2.1 6,-1.6 1,-0.2 5,-1.2 0.939 113.5 48.3 -60.5 -39.5 28.7 8.9 -2.4 139 142 A N H ><5S+ 0 0 65 -4,-3.0 3,-1.5 1,-0.2 -2,-0.2 0.924 103.0 61.5 -65.5 -44.6 31.1 7.4 -4.9 140 143 A A H 3<5S+ 0 0 86 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.811 111.5 36.4 -53.7 -35.1 28.4 5.4 -6.7 141 144 A D T 3<5S- 0 0 91 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.328 113.8-106.0-110.1 12.9 26.3 8.4 -7.8 142 145 A G T <>5S+ 0 0 37 -3,-1.5 4,-2.3 -4,-0.3 5,-0.2 0.465 86.4 119.4 82.5 1.7 29.1 10.9 -8.5 143 146 A T H > S+ 0 0 13 -6,-1.6 4,-3.0 1,-0.2 5,-0.3 0.960 110.1 45.7 -53.7 -54.5 32.1 12.3 -4.2 145 148 A Q H > S+ 0 0 122 -7,-0.3 4,-1.4 1,-0.2 -1,-0.2 0.936 115.1 47.7 -56.6 -47.9 33.6 13.5 -7.4 146 149 A A H X S+ 0 0 40 -4,-2.3 4,-1.0 1,-0.2 3,-0.4 0.957 115.8 42.8 -56.0 -55.0 31.5 16.6 -7.5 147 150 A E H X S+ 0 0 0 -4,-3.1 4,-2.4 1,-0.2 3,-0.3 0.853 106.3 60.0 -68.0 -36.4 32.1 17.6 -3.9 148 151 A D H X S+ 0 0 21 -4,-3.0 4,-3.1 -5,-0.3 -1,-0.2 0.884 99.9 57.0 -60.9 -35.9 35.9 16.9 -3.8 149 152 A R H X S+ 0 0 164 -4,-1.4 4,-1.6 -3,-0.4 -1,-0.2 0.900 108.8 48.3 -60.5 -37.6 36.4 19.4 -6.6 150 153 A I H X S+ 0 0 15 -4,-1.0 4,-1.9 -3,-0.3 -2,-0.2 0.921 111.1 48.0 -69.1 -43.7 34.8 21.9 -4.3 151 154 A F H X S+ 0 0 0 -4,-2.4 4,-2.9 1,-0.2 5,-0.3 0.924 107.4 57.1 -67.1 -37.4 36.8 21.0 -1.2 152 155 A A H X S+ 0 0 40 -4,-3.1 4,-2.8 1,-0.2 -1,-0.2 0.934 106.8 48.9 -55.0 -44.1 40.0 21.1 -3.3 153 156 A T H X S+ 0 0 71 -4,-1.6 4,-1.9 -5,-0.2 -1,-0.2 0.924 109.8 53.1 -60.9 -40.0 39.2 24.8 -4.2 154 157 A A H >X>S+ 0 0 1 -4,-1.9 5,-2.1 2,-0.2 3,-0.6 0.982 110.8 45.2 -57.6 -55.9 38.6 25.5 -0.5 155 158 A A H ><5S+ 0 0 19 -4,-2.9 3,-1.5 1,-0.3 152,-0.6 0.916 111.2 53.5 -55.6 -43.2 41.9 24.1 0.5 156 159 A A H 3<5S+ 0 0 89 -4,-2.8 -1,-0.3 -5,-0.3 -2,-0.2 0.848 109.7 48.6 -65.4 -25.8 43.6 26.0 -2.3 157 160 A Q H <<5S- 0 0 69 -4,-1.9 -1,-0.3 -3,-0.6 -2,-0.2 0.443 121.4-106.3 -97.9 10.1 42.1 29.2 -1.2 158 161 A G T <<5S+ 0 0 10 -3,-1.5 2,-0.3 -4,-0.5 -3,-0.2 0.590 72.6 137.8 89.9 6.7 43.1 28.6 2.5 159 162 A Q < - 0 0 1 -5,-2.1 2,-0.7 -6,-0.2 -1,-0.3 -0.668 45.9-138.1 -83.6 142.9 39.7 27.8 3.9 160 163 A T E -f 126 0B 0 -35,-2.6 -33,-2.5 -2,-0.3 2,-0.5 -0.899 11.2-163.1-106.5 112.8 39.4 24.9 6.4 161 164 A F E -f 127 0B 0 -2,-0.7 35,-3.3 33,-0.4 2,-0.5 -0.829 8.8-159.7 -85.9 129.4 36.5 22.5 6.1 162 165 A S E -fg 128 196B 0 -35,-2.7 -33,-2.3 -2,-0.5 2,-0.4 -0.962 12.0-173.1-111.3 125.1 36.1 20.4 9.3 163 166 A V E -fg 129 197B 0 33,-3.0 35,-2.1 -2,-0.5 -33,-0.2 -0.961 26.4-118.7-129.9 128.9 34.1 17.2 8.9 164 167 A S E - g 0 198B 0 -35,-2.2 26,-0.3 -2,-0.4 35,-0.2 -0.362 19.0-143.4 -58.5 135.0 32.8 14.6 11.4 165 168 A S - 0 0 1 33,-1.7 22,-0.6 1,-0.3 2,-0.2 0.742 54.2 -92.9 -75.3 -24.0 34.4 11.2 10.8 166 169 A G - 0 0 0 32,-0.3 65,-2.1 65,-0.2 -1,-0.3 -0.554 12.5-119.3 129.7 165.6 31.2 9.4 11.7 167 170 A D S S+ 0 0 5 63,-0.2 62,-0.9 -2,-0.2 63,-0.2 0.004 94.2 80.3-126.5 19.7 29.3 7.8 14.6 168 171 A E B > S-m 229 0F 3 1,-0.4 3,-2.2 60,-0.2 62,-0.2 0.215 83.7-144.6-113.3 11.9 29.1 4.3 13.2 169 172 A G T 3 S- 0 0 1 60,-2.4 -1,-0.4 1,-0.3 3,-0.4 -0.345 71.2 -22.3 55.8-142.6 32.6 3.3 14.1 170 173 A V T 3 S+ 0 0 0 161,-1.8 15,-2.6 1,-0.2 3,-0.3 0.479 130.9 77.1 -72.1 -6.0 34.1 1.0 11.4 171 174 A Y B X +o 185 0G 0 -3,-2.2 6,-2.5 13,-0.2 3,-0.6 -0.182 50.2 131.0-103.8 42.1 30.5 0.0 10.2 172 175 A E T 3> S+ 0 0 4 13,-0.5 4,-0.7 -3,-0.4 -38,-0.4 0.875 76.0 40.4 -61.2 -42.6 29.6 3.1 8.3 173 176 A a T 34 S+ 0 0 45 -3,-0.3 2,-1.4 1,-0.2 -1,-0.2 0.532 91.5 90.3 -93.1 -2.9 28.4 1.4 5.1 174 177 A N T <> S- 0 0 46 -3,-0.6 4,-2.3 1,-0.2 -1,-0.2 -0.546 127.0 -53.4 -90.8 76.1 26.5 -1.5 6.8 175 178 A N T 4 S- 0 0 135 -2,-1.4 -1,-0.2 1,-0.2 -2,-0.1 0.893 106.0 -59.3 62.8 34.7 23.1 0.0 7.2 176 179 A R T < S- 0 0 76 -4,-0.7 -4,-0.2 1,-0.2 -1,-0.2 0.976 124.2 -9.2 54.5 62.7 24.7 3.0 8.9 177 180 A G T 4 S+ 0 0 0 -6,-2.5 50,-2.6 1,-0.3 -2,-0.2 0.510 83.0 143.2 108.4 4.4 26.4 1.2 11.8 178 181 A Y < - 0 0 79 -4,-2.3 -1,-0.3 -7,-0.3 48,-0.1 -0.647 62.2 -98.3 -82.6 133.4 25.2 -2.4 12.1 179 182 A P + 0 0 45 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.185 44.6 173.0 -52.1 134.8 28.0 -4.7 13.1 180 183 A D > - 0 0 63 1,-0.4 3,-2.5 3,-0.2 -2,-0.0 -0.228 36.3-126.5-144.8 40.0 29.6 -6.5 10.2 181 184 A G T 3 S- 0 0 22 1,-0.3 -1,-0.4 152,-0.1 152,-0.2 -0.214 83.8 -6.7 54.2-123.9 32.5 -8.3 11.7 182 185 A S T 3 S+ 0 0 83 154,-0.1 2,-0.9 -3,-0.1 -1,-0.3 0.332 103.6 113.1 -87.3 5.7 35.8 -7.5 9.9 183 186 A T < - 0 0 79 -3,-2.5 2,-0.3 -12,-0.0 -3,-0.2 -0.724 48.4-176.5 -85.5 108.5 34.0 -5.5 7.2 184 187 A Y + 0 0 77 -2,-0.9 2,-0.3 -13,-0.1 -13,-0.2 -0.824 9.5 164.6-112.5 145.8 35.2 -1.9 7.7 185 188 A S B -o 171 0G 24 -15,-2.6 -13,-0.5 -2,-0.3 47,-0.4 -0.898 19.8-135.0-146.9 170.8 34.2 1.3 5.9 186 189 A V - 0 0 5 -2,-0.3 -51,-2.4 -15,-0.1 -50,-0.3 -0.877 18.8-106.1-135.5 168.8 34.3 5.1 6.2 187 190 A S E > -L 134 0E 0 -22,-0.6 4,-1.4 -2,-0.3 -53,-0.2 -0.681 33.9-110.4 -97.7 143.5 32.2 8.2 5.8 188 191 A W E 4 S+L 133 0E 0 -55,-3.2 -55,-1.9 -2,-0.3 -51,-0.0 -0.887 96.5 26.5-104.0 143.9 32.2 10.9 3.2 189 192 A P T >4 S+ 0 0 1 0, 0.0 3,-1.4 0, 0.0 -1,-0.3 -0.955 116.8 65.0 -82.5 13.3 33.0 13.8 3.2 190 193 A A T 34 S+ 0 0 0 -26,-0.3 -2,-0.2 1,-0.2 5,-0.2 0.846 94.6 62.1 -62.6 -30.9 35.4 13.0 6.0 191 194 A S T 3< S+ 0 0 0 -4,-1.4 -1,-0.2 43,-0.1 44,-0.2 0.598 79.5 109.1 -74.3 -7.8 37.5 10.7 3.7 192 195 A S X - 0 0 0 -3,-1.4 3,-0.7 1,-0.1 5,-0.1 -0.416 66.0-144.2 -66.5 143.2 38.4 13.6 1.4 193 196 A P T 3 S+ 0 0 19 0, 0.0 -1,-0.1 0, 0.0 116,-0.1 0.667 96.2 68.0 -76.9 -17.2 42.0 14.8 1.6 194 197 A N T 3 S+ 0 0 34 2,-0.1 -33,-0.4 115,-0.0 2,-0.3 0.310 98.5 57.6 -87.3 11.4 40.9 18.4 1.1 195 198 A V S < S- 0 0 0 -3,-0.7 2,-0.5 -5,-0.2 -33,-0.2 -0.890 85.0-110.7-131.2 166.0 39.2 18.5 4.5 196 199 A I E -g 162 0B 0 -35,-3.3 -33,-3.0 -2,-0.3 2,-0.5 -0.866 31.5-150.2 -94.6 126.6 40.1 18.0 8.2 197 200 A A E -g 163 0B 0 -2,-0.5 61,-3.5 -35,-0.2 62,-1.8 -0.860 9.3-162.1-104.4 129.3 38.5 14.9 9.6 198 201 A V E -gh 164 259B 0 -35,-2.1 -33,-1.7 -2,-0.5 -32,-0.3 -0.934 4.4-166.0-118.7 113.6 37.7 14.9 13.3 199 202 A G E - h 0 260B 0 60,-3.1 62,-2.0 -2,-0.5 2,-0.4 -0.077 22.2-100.1 -88.5-169.6 37.1 11.8 15.3 200 203 A G E - h 0 261B 0 147,-0.5 17,-1.9 60,-0.2 2,-0.3 -0.889 26.6-167.7-126.0 146.8 35.6 11.3 18.7 201 204 A T E -Ih 216 262B 0 60,-2.1 62,-3.2 -2,-0.4 63,-2.4 -0.777 28.9-119.5-118.7 167.5 36.7 10.7 22.3 202 205 A T E -I 215 0B 19 13,-2.7 13,-1.8 -2,-0.3 2,-0.5 -0.948 41.9-147.1 -96.1 116.9 35.4 9.8 25.7 203 206 A L E -I 214 0B 0 -2,-0.6 -200,-0.5 11,-0.2 2,-0.4 -0.829 16.4-170.8-106.6 121.9 36.3 12.8 27.8 204 207 A Y E -I 213 0B 69 9,-3.0 8,-2.9 -2,-0.5 9,-1.5 -0.879 7.1-169.9-110.1 135.6 37.2 12.6 31.5 205 208 A T E -I 211 0B 0 -204,-2.2 6,-0.2 -2,-0.4 5,-0.1 -0.914 22.8-110.8-126.8 150.6 37.6 15.7 33.7 206 209 A T > - 0 0 50 4,-2.6 3,-2.4 -2,-0.3 6,-0.1 -0.267 40.0-100.7 -70.2 167.5 39.0 16.3 37.2 207 210 A S T 3 S+ 0 0 134 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.873 129.1 52.8 -51.9 -36.5 36.7 17.3 40.1 208 211 A A T 3 S- 0 0 95 1,-0.1 -1,-0.3 2,-0.0 -2,-0.1 0.569 124.1-107.6 -80.1 -3.2 37.9 20.9 39.4 209 212 A G S < S+ 0 0 18 -3,-2.4 -2,-0.1 1,-0.3 3,-0.1 0.508 72.7 138.0 92.7 4.1 37.0 20.5 35.7 210 213 A A - 0 0 48 1,-0.1 -4,-2.6 -5,-0.1 -1,-0.3 -0.369 67.1 -80.7 -74.7 168.1 40.5 20.3 34.3 211 214 A Y E +I 205 0B 50 -199,-0.4 -6,-0.2 -6,-0.2 -1,-0.1 -0.463 51.4 167.4 -59.3 130.6 41.4 17.8 31.5 212 215 A S E - 0 0 59 -8,-2.9 2,-0.3 1,-0.3 -7,-0.2 0.716 52.7 -51.9-111.4 -56.1 42.0 14.4 33.0 213 216 A N E -I 204 0B 66 -9,-1.5 -9,-3.0 2,-0.0 2,-0.4 -0.995 38.2-131.1-170.3 173.5 42.1 12.0 30.0 214 217 A E E -I 203 0B 10 -2,-0.3 113,-0.5 -11,-0.2 114,-0.4 -0.999 15.4-178.7-138.5 135.3 40.5 10.7 26.8 215 218 A T E -I 202 0B 27 -13,-1.8 -13,-2.7 -2,-0.4 114,-0.2 -0.680 48.7 -67.7-116.4 176.0 39.7 7.2 25.6 216 219 A V E -I 201 0B 7 112,-2.7 2,-0.8 -2,-0.2 -15,-0.2 -0.350 51.8-112.6 -62.5 144.9 38.2 6.2 22.3 217 220 A W + 0 0 3 -17,-1.9 13,-1.9 130,-0.1 2,-0.2 -0.701 60.3 138.5 -75.2 118.1 34.5 7.1 21.8 218 221 A N E +N 229 0F 47 -2,-0.8 11,-0.3 11,-0.2 3,-0.1 -0.675 20.1 169.9-158.9 99.5 32.6 3.8 21.8 219 222 A E E - 0 0 83 9,-2.8 10,-0.1 1,-0.3 -2,-0.0 0.149 44.0-128.9-102.1 26.8 29.3 3.5 23.6 220 223 A G E - 0 0 19 8,-0.4 8,-1.8 112,-0.2 -1,-0.3 -0.133 50.8 -18.9 67.9-160.4 28.3 0.1 22.2 221 224 A L E -N 227 0F 59 6,-0.2 6,-0.2 -3,-0.1 -43,-0.0 -0.538 55.6-138.3 -87.3 145.6 25.0 -0.8 20.6 222 225 A D > - 0 0 52 4,-2.6 3,-1.1 -2,-0.2 -1,-0.1 -0.143 45.1 -84.6 -82.5-167.5 21.7 1.0 20.9 223 226 A S T 3 S+ 0 0 129 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.658 131.6 57.8 -76.4 -10.5 18.4 -0.8 21.3 224 227 A N T 3 S- 0 0 118 2,-0.2 -1,-0.3 0, 0.0 3,-0.1 0.627 120.7-108.4 -89.6 -9.3 18.3 -1.1 17.6 225 228 A G S < S+ 0 0 24 -3,-1.1 2,-0.4 1,-0.3 -2,-0.1 0.509 73.3 141.2 93.3 13.0 21.6 -3.0 17.5 226 229 A K - 0 0 13 -48,-0.1 -4,-2.6 1,-0.0 -1,-0.3 -0.729 50.9-121.7 -93.0 135.3 23.4 -0.0 15.9 227 230 A L E - N 0 221F 0 -50,-2.6 2,-0.5 -2,-0.4 -6,-0.2 -0.520 15.8-159.0 -75.8 138.2 27.0 0.9 17.0 228 231 A W E + 0 0 97 -8,-1.8 -9,-2.8 -2,-0.2 -8,-0.4 -0.937 43.7 113.2-118.6 103.8 27.7 4.3 18.4 229 232 A A E -mN 168 218F 0 -62,-0.9 -60,-2.4 -2,-0.5 -11,-0.2 -0.967 68.5 -67.6-167.2 161.6 31.5 5.0 18.1 230 233 A T - 0 0 0 -13,-1.9 -63,-0.2 -2,-0.3 2,-0.1 -0.339 47.4-122.4 -65.4 127.1 34.0 7.2 16.3 231 234 A G + 0 0 3 -65,-2.1 2,-0.3 -2,-0.2 -31,-0.2 -0.461 47.4 149.2 -65.4 139.4 34.4 6.8 12.6 232 235 A G + 0 0 1 -47,-0.4 2,-0.3 -63,-0.3 106,-0.2 -0.892 13.7 84.4-177.0 146.0 38.0 5.8 11.6 233 236 A G E S-P 256 0H 1 23,-2.4 23,-3.1 -2,-0.3 2,-0.3 -0.968 71.1 -63.9 153.9-144.8 39.9 3.9 8.9 234 237 A Y E -P 255 0H 87 -2,-0.3 21,-0.2 21,-0.3 2,-0.1 -0.962 45.7-101.2-138.7 156.4 41.0 4.8 5.4 235 238 A S E - 0 0 0 19,-2.5 19,-0.1 -2,-0.3 5,-0.1 -0.458 15.9-148.7 -73.0 146.5 39.3 5.6 2.2 236 239 A V E S+ 0 0 81 -2,-0.1 -1,-0.1 17,-0.1 3,-0.0 0.692 96.9 29.3 -86.4 -11.7 38.9 3.0 -0.4 237 240 A Y E S+ 0 0 93 17,-0.1 2,-0.4 2,-0.1 -1,-0.1 0.759 99.7 81.0-111.7 -48.2 39.1 5.6 -3.2 238 241 A E E S- 0 0 24 16,-0.1 16,-2.5 1,-0.1 -3,-0.2 -0.507 74.2-129.5 -74.7 126.9 41.2 8.5 -2.1 239 242 A S E -P 253 0H 84 -2,-0.4 14,-0.4 14,-0.3 -1,-0.1 -0.300 35.4 -90.1 -64.0 151.9 44.9 8.2 -2.3 240 243 A K - 0 0 45 12,-1.4 14,-0.2 14,-0.1 2,-0.1 -0.501 37.8-127.9 -65.7 123.3 47.1 9.0 0.7 241 244 A P > - 0 0 18 0, 0.0 3,-2.2 0, 0.0 4,-0.3 -0.489 26.7-117.0 -67.8 145.2 48.2 12.7 0.7 242 245 A S G > S+ 0 0 97 1,-0.3 3,-1.6 2,-0.2 4,-0.2 0.767 110.0 67.9 -67.4 -22.2 51.9 12.7 1.1 243 246 A W G > S+ 0 0 71 1,-0.3 3,-0.9 2,-0.1 -1,-0.3 0.766 95.4 60.4 -61.5 -21.3 51.9 14.5 4.5 244 247 A Q G X S+ 0 0 0 -3,-2.2 3,-2.5 1,-0.2 -1,-0.3 0.582 76.5 90.6 -80.0 -6.6 50.3 11.3 5.9 245 248 A S G < + 0 0 81 -3,-1.6 -1,-0.2 -4,-0.3 -2,-0.1 0.748 69.1 76.9 -66.4 -14.8 53.3 9.2 4.9 246 249 A V G < S+ 0 0 67 -3,-0.9 2,-1.1 -4,-0.2 -1,-0.3 0.726 78.3 77.6 -65.1 -20.7 54.7 10.0 8.3 247 250 A V S X S- 0 0 16 -3,-2.5 3,-0.6 -4,-0.1 -1,-0.1 -0.760 84.7-154.0 -87.3 99.3 52.2 7.4 9.6 248 251 A S T 3 + 0 0 114 -2,-1.1 -2,-0.1 1,-0.2 -3,-0.0 -0.427 64.3 34.0 -81.7 154.4 54.2 4.3 8.6 249 252 A G T 3 S+ 0 0 78 1,-0.3 -1,-0.2 -4,-0.1 -4,-0.0 0.720 88.5 117.8 82.9 24.8 52.7 0.9 7.9 250 253 A T < - 0 0 26 -3,-0.6 -1,-0.3 -5,-0.1 5,-0.0 -0.887 67.5 -95.2-122.1 155.4 49.4 2.1 6.4 251 254 A P - 0 0 50 0, 0.0 2,-1.3 0, 0.0 -1,-0.1 -0.054 43.2 -96.7 -61.5 168.2 48.0 1.7 2.9 252 255 A G S S+ 0 0 44 2,-0.1 -12,-1.4 -13,-0.1 2,-0.3 -0.191 92.3 103.8 -80.7 44.5 48.3 4.3 0.1 253 256 A R E S-P 239 0H 95 -2,-1.3 2,-0.5 -14,-0.4 -14,-0.3 -0.803 87.2 -84.6-122.6 160.5 44.9 5.7 1.0 254 257 A R E - 0 0 3 -16,-2.5 -19,-2.5 -2,-0.3 2,-0.3 -0.572 48.9-148.1 -67.3 119.1 43.6 8.8 2.8 255 258 A L E -P 234 0H 0 -2,-0.5 -21,-0.3 -21,-0.2 -1,-0.0 -0.705 23.2-115.2 -89.2 141.6 43.7 7.8 6.5 256 259 A L E +P 233 0H 0 -23,-3.1 -23,-2.4 -2,-0.3 93,-0.2 -0.977 68.8 25.9-145.5 158.3 41.1 9.3 8.9 257 260 A P - 0 0 0 0, 0.0 -59,-0.2 0, 0.0 88,-0.1 0.605 52.9-162.3 -82.4 178.7 40.3 10.9 11.2 258 261 A D S S- 0 0 1 -61,-3.5 92,-2.2 1,-0.3 2,-0.3 0.876 73.3 -7.9 -87.8 -42.9 43.1 13.5 11.5 259 262 A I E -h 198 0B 0 -62,-1.8 -60,-3.1 90,-0.2 2,-0.3 -0.894 68.4-145.0-145.5 168.6 42.4 14.7 15.0 260 263 A S E +h 199 0B 0 91,-2.0 2,-0.3 -62,-0.3 -60,-0.2 -0.982 12.8 178.8-143.9 153.3 39.6 14.0 17.6 261 264 A F E -h 200 0B 0 -62,-2.0 -60,-2.1 -2,-0.3 25,-0.2 -0.869 53.0 -40.2-141.2 177.8 37.7 15.7 20.4 262 265 A D E +h 201 0B 0 -2,-0.3 -60,-0.2 -62,-0.3 27,-0.2 -0.089 61.7 146.4 -41.5 128.9 34.9 14.9 22.9 263 266 A A + 0 0 0 -62,-3.2 19,-4.0 22,-0.1 -61,-0.2 0.448 26.6 113.1-143.7 -20.1 32.2 12.8 21.3 264 267 A A > - 0 0 0 -63,-2.4 3,-1.1 17,-0.2 -61,-0.1 -0.390 60.2-141.2 -60.2 132.6 30.7 10.4 23.9 265 268 A Q G > S+ 0 0 93 1,-0.2 3,-1.7 2,-0.2 -1,-0.2 0.889 103.5 61.1 -59.1 -37.6 27.1 11.2 24.7 266 269 A G G 3 S+ 0 0 25 1,-0.3 -1,-0.2 -262,-0.1 -2,-0.1 0.678 118.3 27.3 -64.3 -16.7 28.0 10.3 28.3 267 270 A T G < S+ 0 0 2 -3,-1.1 -1,-0.3 -265,-0.1 -2,-0.2 0.086 105.6 133.5-126.3 27.0 30.6 13.0 28.4 268 271 A G < - 0 0 0 -3,-1.7 -263,-2.1 1,-0.2 2,-0.3 0.302 59.3 -79.6 -71.1-175.3 28.7 15.1 25.8 269 272 A A E -aB 5 280A 0 11,-3.7 11,-3.0 -265,-0.2 2,-0.8 -0.666 31.7-128.3 -92.3 147.9 27.7 18.8 25.4 270 273 A L E - B 0 279A 47 -265,-2.6 2,-0.4 -2,-0.3 9,-0.2 -0.843 40.3-179.5 -96.2 115.2 24.7 20.3 27.1 271 274 A I E - B 0 278A 0 7,-3.2 7,-2.5 -2,-0.8 2,-0.5 -0.903 31.4-123.7-124.9 135.4 22.9 22.0 24.3 272 275 A Y E + B 0 277A 41 -2,-0.4 2,-0.4 5,-0.2 5,-0.3 -0.689 34.3 175.5 -80.4 124.2 19.7 24.1 24.1 273 276 A N E > S- B 0 276A 23 3,-3.7 3,-2.3 -2,-0.5 -197,-0.1 -0.979 72.1 -16.5-132.4 119.9 17.3 22.4 21.6 274 277 A Y T 3 S- 0 0 84 -2,-0.4 -1,-0.1 1,-0.3 3,-0.1 0.889 130.6 -54.1 48.9 40.6 13.8 23.9 21.2 275 278 A G T 3 S+ 0 0 25 1,-0.2 2,-0.4 -238,-0.1 -1,-0.3 0.398 119.3 112.6 80.7 -3.9 14.4 25.7 24.4 276 279 A Q E < -B 273 0A 133 -3,-2.3 -3,-3.7 -5,-0.0 2,-0.4 -0.864 67.2-126.5-110.1 136.8 15.3 22.4 26.2 277 280 A L E +B 272 0A 83 -2,-0.4 2,-0.3 -5,-0.3 -5,-0.2 -0.618 35.5 176.7 -80.1 128.6 18.7 21.5 27.6 278 281 A Q E -B 271 0A 81 -7,-2.5 -7,-3.2 -2,-0.4 2,-0.8 -0.973 33.3-122.4-134.0 154.5 20.0 18.2 26.3 279 282 A Q E +B 270 0A 65 -2,-0.3 2,-0.4 -9,-0.2 -9,-0.2 -0.848 42.0 176.6 -98.0 110.1 23.2 16.1 26.6 280 283 A I E +B 269 0A 34 -11,-3.0 -11,-3.7 -2,-0.8 2,-0.1 -0.927 11.2 161.1-124.6 140.6 24.5 15.5 23.1 281 284 A G + 0 0 14 -2,-0.4 -17,-0.2 -13,-0.3 3,-0.1 -0.285 16.4 115.5-128.2-151.2 27.6 13.8 21.7 282 285 A G S >> S- 0 0 5 -19,-4.0 3,-1.8 2,-0.2 4,-1.5 -0.154 83.6 -74.2 99.1 170.0 28.8 12.2 18.4 283 286 A T H 3> S+ 0 0 0 88,-0.5 4,-2.2 1,-0.3 -1,-0.1 0.699 129.3 75.4 -71.3 -14.2 31.6 13.2 16.1 284 287 A S H 34 S+ 0 0 1 87,-1.9 -1,-0.3 2,-0.2 -2,-0.2 0.696 99.7 43.3 -61.5 -24.5 29.0 15.9 15.3 285 288 A L H <> S+ 0 0 0 -3,-1.8 4,-1.5 86,-0.4 -2,-0.2 0.868 109.7 52.6 -85.4 -48.2 30.2 17.4 18.6 286 289 A A H X S+ 0 0 0 -4,-1.5 4,-2.3 -25,-0.2 -2,-0.2 0.887 104.7 57.5 -58.9 -36.6 33.9 16.9 18.2 287 290 A S H X S+ 0 0 0 -4,-2.2 4,-2.6 1,-0.2 -1,-0.2 0.957 106.5 45.8 -62.0 -52.2 34.0 18.7 14.8 288 291 A P H > S+ 0 0 0 0, 0.0 4,-2.2 0, 0.0 -1,-0.2 0.768 109.0 57.7 -64.7 -22.2 32.5 22.0 16.0 289 292 A I H X S+ 0 0 0 -4,-1.5 4,-2.3 2,-0.2 5,-0.3 0.954 109.5 44.8 -67.8 -48.3 34.8 21.9 19.0 290 293 A F H X S+ 0 0 1 -4,-2.3 4,-3.0 1,-0.2 5,-0.2 0.930 111.6 53.6 -53.5 -47.6 37.7 21.8 16.5 291 294 A V H X S+ 0 0 0 -4,-2.6 4,-2.1 1,-0.2 -1,-0.2 0.915 110.5 45.5 -58.6 -45.8 36.1 24.5 14.5 292 295 A G H X S+ 0 0 0 -4,-2.2 4,-1.3 2,-0.2 -1,-0.2 0.909 116.0 45.4 -63.4 -44.7 35.8 26.9 17.5 293 296 A L H X S+ 0 0 0 -4,-2.3 4,-1.5 1,-0.2 -2,-0.2 0.897 113.2 50.3 -65.2 -42.0 39.3 26.2 18.7 294 297 A W H X S+ 0 0 1 -4,-3.0 4,-1.8 -5,-0.3 -1,-0.2 0.845 104.7 57.9 -67.2 -36.5 40.8 26.6 15.2 295 298 A A H X S+ 0 0 0 -4,-2.1 4,-2.6 -5,-0.2 -1,-0.2 0.839 103.1 54.8 -63.2 -33.2 38.9 29.9 14.7 296 299 A R H X S+ 0 0 10 -4,-1.3 4,-2.6 2,-0.2 -2,-0.2 0.960 107.4 48.2 -63.3 -48.2 40.8 31.2 17.8 297 300 A L H X S+ 0 0 1 -4,-1.5 4,-0.8 2,-0.2 -2,-0.2 0.836 111.3 52.1 -60.3 -33.7 44.2 30.3 16.3 298 301 A Q H ><>S+ 0 0 0 -4,-1.8 5,-3.7 2,-0.2 3,-1.3 0.960 110.0 47.2 -65.3 -50.6 43.1 32.0 13.1 299 302 A S H ><5S+ 0 0 18 -4,-2.6 3,-1.0 1,-0.3 -2,-0.2 0.867 110.9 53.6 -60.2 -33.2 42.1 35.1 15.0 300 303 A A H 3<5S+ 0 0 44 -4,-2.6 -1,-0.3 1,-0.2 -2,-0.2 0.775 114.6 41.3 -69.2 -21.5 45.5 34.8 16.7 301 304 A N T X<5S- 0 0 40 -3,-1.3 3,-2.5 -4,-0.8 -1,-0.2 -0.074 117.6-102.0-122.1 32.6 47.2 34.7 13.3 302 305 A S T < 5 - 0 0 110 -3,-1.0 -3,-0.2 1,-0.3 -4,-0.1 0.811 69.2 -73.8 54.9 32.0 45.3 37.3 11.4 303 306 A N T 3 + 0 0 0 0, 0.0 4,-2.8 0, 0.0 5,-0.2 0.377 61.5 101.6 -88.4 4.6 46.5 22.8 8.0 309 312 A A H > S+ 0 0 2 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.938 86.4 44.4 -57.2 -53.5 46.6 19.1 7.2 310 313 A A H > S+ 0 0 44 -3,-0.3 4,-2.1 1,-0.2 -1,-0.2 0.873 116.5 49.4 -56.9 -37.5 50.3 18.9 6.1 311 314 A S H > S+ 0 0 26 -4,-0.3 4,-2.9 2,-0.2 5,-0.3 0.873 107.3 52.8 -72.5 -39.8 51.3 21.1 9.0 312 315 A F H X S+ 0 0 0 -4,-2.8 4,-2.8 1,-0.2 5,-0.5 0.953 111.6 47.1 -58.4 -45.8 49.4 19.0 11.6 313 316 A Y H X S+ 0 0 1 -4,-2.3 4,-1.3 -5,-0.2 -2,-0.2 0.914 116.5 42.2 -69.7 -36.9 51.1 15.9 10.4 314 317 A S H X S+ 0 0 65 -4,-2.1 4,-1.3 -5,-0.2 -1,-0.2 0.932 119.2 43.1 -74.7 -39.2 54.5 17.4 10.4 315 318 A A H X S+ 0 0 0 -4,-2.9 4,-0.9 2,-0.2 -2,-0.2 0.935 117.6 42.8 -73.1 -44.2 54.2 19.3 13.7 316 319 A I H >< S+ 0 0 3 -4,-2.8 3,-0.6 -5,-0.3 6,-0.2 0.919 111.1 54.2 -68.9 -44.6 52.5 16.6 15.8 317 320 A S H 3< S+ 0 0 48 -4,-1.3 -1,-0.2 -5,-0.5 -2,-0.2 0.865 119.9 34.7 -56.0 -36.1 54.6 13.7 14.5 318 321 A S H 3< S+ 0 0 80 -4,-1.3 -1,-0.3 1,-0.2 -2,-0.2 0.543 126.0 42.3 -95.2 -8.1 57.7 15.6 15.6 319 322 A T X< + 0 0 33 -4,-0.9 3,-2.5 -3,-0.6 -1,-0.2 -0.595 58.7 175.4-141.8 72.1 56.2 17.3 18.6 320 323 A P G > S+ 0 0 96 0, 0.0 3,-1.9 0, 0.0 5,-0.1 0.751 74.1 74.0 -54.7 -23.7 54.0 14.9 20.7 321 324 A S G 3 S+ 0 0 69 1,-0.3 36,-0.1 3,-0.1 37,-0.1 0.725 80.6 75.3 -67.0 -12.7 53.4 17.6 23.4 322 325 A L G < S+ 0 0 4 -3,-2.5 32,-2.7 -6,-0.2 2,-0.3 0.681 101.3 37.9 -69.9 -14.0 51.0 19.3 20.9 323 326 A V E < S-Q 353 0I 19 -3,-1.9 2,-0.8 30,-0.2 30,-0.2 -0.900 76.8-116.1-136.4 164.0 48.3 16.7 21.5 324 327 A H E -Q 352 0I 40 28,-3.2 28,-1.2 -2,-0.3 2,-0.7 -0.901 41.7-139.2 -92.1 104.5 46.6 14.4 24.0 325 328 A D - 0 0 54 -2,-0.8 2,-0.4 26,-0.2 26,-0.2 -0.486 8.6-144.0 -72.9 109.2 47.5 11.0 22.6 326 329 A V + 0 0 0 -2,-0.7 15,-0.6 1,-0.2 -111,-0.1 -0.640 31.9 161.4 -73.8 126.5 44.5 8.7 22.8 327 330 A K + 0 0 126 -113,-0.5 2,-0.5 -2,-0.4 -1,-0.2 0.501 43.5 71.8-122.1 -14.8 45.7 5.2 23.7 328 331 A S S S+ 0 0 75 -114,-0.4 -112,-2.7 13,-0.1 2,-0.2 -0.949 76.6 23.4-121.9 129.1 42.8 3.1 25.0 329 332 A G - 0 0 32 -2,-0.5 11,-3.6 11,-0.2 2,-0.3 -0.553 59.4-106.2 125.1 177.7 39.8 1.6 23.2 330 333 A N B -R 339 0J 50 9,-0.3 9,-0.2 -2,-0.2 -100,-0.1 -0.960 9.0-140.3-138.5 162.3 38.5 0.5 19.9 331 334 A N S S+ 0 0 0 7,-1.8 -161,-1.8 -2,-0.3 6,-0.1 -0.108 80.6 68.1-113.3 37.3 36.0 1.8 17.3 332 335 A G S S- 0 0 1 4,-0.4 2,-0.3 6,-0.2 5,-0.2 -0.291 73.6-115.7-126.8-149.6 34.4 -1.6 16.5 333 336 A Y S > S+ 0 0 107 -152,-0.2 3,-2.0 -2,-0.1 -153,-0.1 -0.971 78.2 16.0-160.0 148.4 32.3 -4.3 18.2 334 337 A G T 3 S- 0 0 57 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.814 135.0 -47.4 61.9 33.0 32.4 -7.9 19.3 335 338 A G T 3 S+ 0 0 79 1,-0.3 -1,-0.3 -154,-0.0 2,-0.1 0.336 118.1 110.3 89.6 -11.3 36.2 -7.9 19.1 336 339 A Y < + 0 0 112 -3,-2.0 -4,-0.4 -6,-0.0 -1,-0.3 -0.408 45.0 63.9 -89.4 177.9 36.3 -6.3 15.6 337 340 A G S S- 0 0 12 -5,-0.2 2,-0.2 -156,-0.2 -5,-0.1 -0.197 84.9 -59.6 103.0 166.7 37.5 -2.7 14.9 338 341 A Y - 0 0 44 -106,-0.2 -7,-1.8 -2,-0.1 2,-0.4 -0.606 49.9-134.7 -82.0 148.7 40.7 -0.7 15.1 339 342 A N B -R 330 0J 116 -2,-0.2 7,-0.4 -9,-0.2 -9,-0.3 -0.830 17.3-112.2-106.0 146.2 42.4 -0.3 18.4 340 343 A A + 0 0 16 -11,-3.6 2,-0.3 -2,-0.4 -11,-0.2 -0.291 47.7 162.1 -66.3 157.1 43.8 2.9 19.8 341 344 A G - 0 0 27 -15,-0.6 2,-0.1 2,-0.3 -13,-0.1 -0.949 42.4 -49.5-160.6 179.9 47.5 3.0 20.2 342 345 A T S S- 0 0 121 -2,-0.3 -15,-0.1 -15,-0.1 -16,-0.0 -0.340 105.6 -12.9 -58.2 131.9 50.7 5.1 20.6 343 346 A G S S+ 0 0 24 7,-0.1 -2,-0.3 -2,-0.1 -17,-0.1 -0.328 125.3 10.6 70.4-152.8 50.8 8.0 18.2 344 347 A W S S+ 0 0 26 -4,-0.1 2,-0.3 -19,-0.1 6,-0.2 -0.341 72.6 173.2 -62.6 133.7 48.5 8.1 15.2 345 348 A D B > -S 349 0K 9 4,-1.4 4,-2.9 -88,-0.1 6,-0.1 -0.948 40.5-115.2-136.0 163.7 45.6 5.5 15.3 346 349 A Y T 4 S+ 0 0 36 -7,-0.4 -113,-0.2 -2,-0.3 -6,-0.1 0.806 109.8 50.0 -69.9 -32.5 42.5 4.8 13.2 347 350 A P T 4 S+ 0 0 0 0, 0.0 -147,-0.5 0, 0.0 -1,-0.2 0.918 133.9 6.9 -70.9 -35.2 39.9 5.5 15.8 348 351 A T T >4 S- 0 0 0 1,-0.3 3,-1.7 -22,-0.1 -149,-0.3 0.525 81.3-150.8-128.4 -5.4 41.3 8.9 16.9 349 352 A G B 3< S-S 345 0K 0 -4,-2.9 -4,-1.4 1,-0.3 -1,-0.3 -0.509 79.5 -14.2 67.3-135.9 44.1 10.0 14.6 350 353 A W T 3 S- 0 0 23 -92,-2.2 -1,-0.3 1,-0.3 2,-0.2 0.606 100.8-126.9 -76.1 -11.8 46.6 12.2 16.5 351 354 A G < - 0 0 0 -3,-1.7 -91,-2.0 -26,-0.2 -1,-0.3 -0.656 51.8 -22.6 94.3-158.6 44.1 12.7 19.3 352 355 A S E -Q 324 0I 0 -28,-1.2 -28,-3.2 -2,-0.2 2,-0.3 -0.650 66.1-112.7 -96.8 151.0 43.0 16.1 20.6 353 356 A L E -Q 323 0I 1 -30,-0.2 2,-0.9 -2,-0.2 -30,-0.2 -0.586 8.5-141.6 -80.1 133.0 44.9 19.4 20.3 354 357 A D > - 0 0 12 -32,-2.7 4,-2.6 -2,-0.3 5,-0.2 -0.851 23.5-160.9 -86.7 106.3 46.5 21.2 23.2 355 358 A I H > S+ 0 0 0 -341,-2.2 4,-3.1 -2,-0.9 5,-0.2 0.924 80.9 49.1 -67.2 -44.9 45.6 24.7 22.0 356 359 A A H > S+ 0 0 29 -341,-1.7 4,-2.1 -342,-0.3 -1,-0.2 0.929 114.7 46.9 -63.7 -37.8 48.1 26.8 24.0 357 360 A K H > S+ 0 0 103 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.914 112.8 49.3 -68.2 -38.4 50.9 24.6 23.1 358 361 A L H X S+ 0 0 2 -4,-2.6 4,-2.6 -36,-0.2 5,-0.2 0.910 109.2 52.7 -65.6 -37.8 49.9 24.6 19.4 359 362 A S H X S+ 0 0 27 -4,-3.1 4,-2.1 -5,-0.2 -2,-0.2 0.935 110.0 48.1 -62.9 -43.0 49.6 28.4 19.5 360 363 A A H X S+ 0 0 45 -4,-2.1 4,-2.4 2,-0.2 5,-0.2 0.912 110.2 51.4 -62.1 -47.6 53.2 28.6 20.8 361 364 A Y H X S+ 0 0 50 -4,-2.4 4,-3.6 1,-0.2 5,-0.3 0.937 112.2 47.4 -50.5 -50.5 54.5 26.2 18.2 362 365 A I H X S+ 0 0 5 -4,-2.6 4,-2.2 1,-0.2 -1,-0.2 0.862 107.0 56.6 -65.3 -31.7 52.8 28.3 15.5 363 366 A R H < S+ 0 0 195 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.950 117.4 35.0 -66.9 -40.4 54.2 31.5 17.0 364 367 A S H < S+ 0 0 95 -4,-2.4 -2,-0.2 1,-0.1 -1,-0.2 0.922 135.0 20.4 -74.9 -43.6 57.7 30.0 16.6 365 368 A N H < S- 0 0 107 -4,-3.6 -3,-0.2 1,-0.2 -2,-0.2 0.464 93.5-128.5-111.1 -1.2 57.4 28.0 13.4 366 369 A G < 0 0 38 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.1 -0.100 360.0 360.0 70.1 177.5 54.4 29.3 11.4 367 370 A F 0 0 54 -5,-0.1 -61,-0.4 -4,-0.1 -55,-0.0 -0.952 360.0 360.0-156.2 360.0 51.8 26.9 10.2 368 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 369 2 B X 0 0 86 0, 0.0 -237,-2.8 0, 0.0 2,-0.2 0.000 360.0 360.0 360.0 -17.8 23.3 11.9 7.5 370 3 B L B K 131 0D 58 -239,-0.2 -239,-0.3 1,-0.2 -86,-0.1 -0.487 360.0 360.0 -68.4 130.3 23.5 14.0 10.6 371 4 B X 0 0 7 -241,-3.0 -87,-1.9 -2,-0.2 -88,-0.5 0.650 360.0 360.0-104.4 360.0 26.5 13.1 12.7