==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER METAL TRANSPORT 25-APR-13 4KEI . COMPND 2 MOLECULE: RYANODINE RECEPTOR 2; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR L.KIMLICKA,F.VAN PETEGEM . 173 5 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8450.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 119 68.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 70 40.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 22 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 11 6.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 10 5.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 4 0 1 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 12 A Q 0 0 109 0, 0.0 136,-1.0 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0-154.7 -27.5 -5.1 3.5 2 13 A F B -A 136 0A 110 134,-0.2 2,-0.4 136,-0.0 134,-0.2 -0.951 360.0-108.4-131.1 151.9 -24.3 -4.6 1.6 3 14 A L + 0 0 4 132,-2.0 75,-3.0 -2,-0.3 2,-0.3 -0.639 44.6 178.3 -76.7 131.5 -23.4 -3.7 -2.0 4 15 A R B > -B 77 0B 15 -2,-0.4 3,-1.1 73,-0.2 52,-0.3 -0.861 33.8 -87.8-130.5 164.9 -21.9 -6.7 -3.9 5 16 A T T 3 S+ 0 0 21 71,-1.8 52,-0.2 -2,-0.3 3,-0.1 -0.355 110.6 35.2 -66.9 154.3 -20.7 -7.5 -7.4 6 17 A D T 3 S+ 0 0 53 50,-2.5 2,-0.2 1,-0.3 -1,-0.2 0.488 87.6 140.9 76.4 4.5 -23.3 -8.7 -9.9 7 18 A D < - 0 0 40 -3,-1.1 49,-1.8 49,-0.5 2,-0.7 -0.566 52.2-136.2 -78.1 139.4 -25.8 -6.3 -8.3 8 19 A E E +C 55 0C 47 -2,-0.2 169,-1.8 47,-0.2 47,-0.3 -0.881 40.7 171.8 -94.1 112.4 -28.2 -4.4 -10.5 9 20 A V E -CD 54 176C 0 45,-3.9 45,-2.6 -2,-0.7 2,-0.4 -0.660 31.5-141.6-122.2 171.4 -28.2 -0.8 -9.1 10 21 A V E - D 0 175C 12 165,-2.8 165,-1.9 -2,-0.2 2,-0.6 -0.992 16.7-140.6-136.0 126.6 -29.5 2.7 -9.8 11 22 A L E + D 0 174C 0 -2,-0.4 15,-2.8 41,-0.3 2,-0.3 -0.770 25.8 178.9 -91.7 122.9 -27.5 5.9 -9.1 12 23 A Q E -ED 25 173C 27 161,-1.7 161,-3.1 -2,-0.6 2,-0.3 -0.888 8.7-177.8-121.9 153.7 -29.5 8.8 -7.6 13 24 A C E -E 24 0C 1 11,-2.1 11,-3.1 -2,-0.3 2,-0.5 -0.957 29.2-111.1-142.9 161.7 -28.6 12.3 -6.5 14 25 A T E -E 23 0C 60 157,-0.5 2,-0.6 -2,-0.3 9,-0.2 -0.846 26.0-164.6-100.6 125.1 -30.4 15.3 -5.0 15 26 A A E +E 22 0C 0 7,-3.3 7,-1.7 -2,-0.5 2,-0.5 -0.927 8.8 179.9-113.4 114.7 -30.9 18.4 -7.2 16 27 A T E +E 21 0C 75 -2,-0.6 2,-0.3 5,-0.2 5,-0.2 -0.949 12.5 150.7-119.6 116.7 -31.9 21.6 -5.4 17 28 A I E > S+E 20 0C 44 3,-1.7 3,-1.9 -2,-0.5 -2,-0.0 -0.988 72.8 2.1-142.1 136.1 -32.5 24.8 -7.3 18 29 A H T 3 S- 0 0 158 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.886 128.3 -63.4 57.1 39.5 -34.8 27.7 -6.3 19 30 A K T 3 S+ 0 0 100 1,-0.2 2,-0.8 -3,-0.0 -1,-0.3 0.464 109.8 127.4 64.5 1.6 -35.8 25.7 -3.2 20 31 A E E < -E 17 0C 61 -3,-1.9 -3,-1.7 2,-0.0 2,-0.4 -0.800 42.7-167.5 -90.7 107.0 -37.2 23.0 -5.5 21 32 A Q E +E 16 0C 142 -2,-0.8 2,-0.3 -5,-0.2 -5,-0.2 -0.763 13.2 162.5-101.3 140.6 -35.6 19.7 -4.5 22 33 A Q E -E 15 0C 65 -7,-1.7 -7,-3.3 -2,-0.4 2,-0.5 -0.992 36.6-116.5-150.7 153.9 -35.8 16.5 -6.6 23 34 A K E -E 14 0C 80 -2,-0.3 18,-0.6 -9,-0.2 2,-0.4 -0.826 30.7-161.9 -93.2 131.8 -34.1 13.2 -6.9 24 35 A L E -EF 13 40C 3 -11,-3.1 -11,-2.1 -2,-0.5 2,-0.4 -0.897 5.4-145.4-114.3 144.7 -32.4 12.5 -10.2 25 36 A C E -EF 12 39C 0 14,-2.2 14,-2.1 -2,-0.4 2,-0.2 -0.896 19.7-118.8-110.8 136.2 -31.3 9.2 -11.7 26 37 A L E + F 0 38C 0 -15,-2.8 2,-0.3 -2,-0.4 -15,-0.3 -0.521 44.6 169.8 -67.6 132.7 -28.2 8.5 -13.8 27 38 A A E + F 0 37C 0 10,-2.5 10,-2.3 -2,-0.2 2,-0.3 -0.926 13.3 176.2-142.8 166.0 -29.2 7.2 -17.2 28 39 A A E - F 0 36C 0 23,-1.2 2,-0.4 -2,-0.3 8,-0.2 -0.974 17.4-143.8-167.6 153.6 -27.7 6.5 -20.6 29 40 A E - 0 0 42 6,-0.6 82,-0.1 -2,-0.3 6,-0.1 -0.948 7.1-155.8-122.6 147.4 -28.4 5.1 -24.1 30 41 A G S S+ 0 0 38 -2,-0.4 2,-1.3 1,-0.1 4,-0.1 0.488 73.3 95.6 -94.4 -5.8 -26.1 3.0 -26.3 31 42 A F S S- 0 0 98 2,-0.1 2,-0.4 3,-0.0 -1,-0.1 -0.636 100.3 -32.7 -92.9 83.2 -27.9 4.1 -29.4 32 43 A G S S+ 0 0 61 -2,-1.3 2,-0.2 2,-0.0 -3,-0.0 -0.915 121.5 34.1 118.7-140.3 -25.9 7.1 -30.7 33 44 A N S S- 0 0 128 -2,-0.4 2,-1.8 1,-0.1 -4,-0.3 -0.390 76.2-137.8 -53.5 117.9 -24.0 9.7 -28.8 34 45 A R + 0 0 34 -2,-0.2 77,-1.3 77,-0.1 2,-0.4 -0.419 54.5 128.7 -86.4 63.7 -22.7 7.8 -25.8 35 46 A L B -G 110 0C 47 -2,-1.8 -6,-0.6 75,-0.2 75,-0.3 -0.928 53.1-126.1-119.8 144.5 -23.3 10.3 -23.0 36 47 A C E +F 28 0C 13 73,-2.4 127,-0.4 -2,-0.4 -8,-0.2 -0.523 29.4 179.6 -82.4 152.7 -25.1 9.9 -19.7 37 48 A F E -F 27 0C 83 -10,-2.3 -10,-2.5 -2,-0.2 2,-0.4 -0.760 24.1-103.3-139.0-173.3 -27.9 12.1 -18.6 38 49 A L E -F 26 0C 25 123,-0.5 2,-0.4 -2,-0.2 -12,-0.2 -0.952 21.1-156.4-125.9 138.9 -30.3 12.6 -15.7 39 50 A E E -F 25 0C 18 -14,-2.1 -14,-2.2 -2,-0.4 2,-0.1 -0.873 16.7-128.5-111.0 144.1 -34.0 11.7 -15.2 40 51 A S E -F 24 0C 66 -2,-0.4 2,-0.2 -16,-0.2 -16,-0.2 -0.460 32.1-149.7 -78.3 161.9 -36.5 13.2 -12.8 41 52 A T 0 0 27 -18,-0.6 -18,-0.1 5,-0.2 -1,-0.0 -0.747 360.0 360.0-131.5 176.2 -38.5 10.8 -10.6 42 53 A S 0 0 140 3,-0.9 3,-0.1 -2,-0.2 -1,-0.0 -0.498 360.0 360.0 86.3 360.0 -41.8 10.2 -8.8 43 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 44 57 A N 0 0 81 0, 0.0 -3,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 79.4 -39.3 8.1 -6.2 45 58 A V - 0 0 97 -3,-0.1 -3,-0.9 -20,-0.0 4,-0.0 -0.932 360.0-124.0-112.2 128.0 -39.3 6.1 -9.4 46 59 A P - 0 0 5 0, 0.0 3,-0.3 0, 0.0 -5,-0.2 -0.341 21.2-121.1 -65.2 147.2 -38.0 7.4 -12.7 47 60 A P S S+ 0 0 117 0, 0.0 2,-0.8 0, 0.0 -6,-0.1 0.944 107.7 32.3 -53.9 -55.3 -40.4 7.3 -15.7 48 61 A D + 0 0 74 1,-0.2 3,-0.2 2,-0.0 -9,-0.0 -0.855 67.9 165.0-108.0 97.0 -38.1 5.1 -17.8 49 62 A L > + 0 0 68 -2,-0.8 3,-2.4 -3,-0.3 -1,-0.2 0.749 59.4 82.3 -83.2 -25.7 -36.2 2.9 -15.4 50 63 A S G > S+ 0 0 75 1,-0.3 3,-0.8 2,-0.2 40,-0.4 0.878 96.3 41.9 -44.4 -50.2 -34.9 0.5 -18.0 51 64 A I G 3 S+ 0 0 31 1,-0.2 -23,-1.2 -3,-0.2 -1,-0.3 0.353 103.0 70.4 -85.6 6.3 -32.0 2.7 -19.0 52 65 A C G < S+ 0 0 0 -3,-2.4 2,-0.5 -25,-0.2 -41,-0.3 0.122 75.5 106.9-108.3 18.7 -31.1 3.6 -15.4 53 66 A T < + 0 0 17 -3,-0.8 36,-2.0 -43,-0.1 37,-0.4 -0.876 40.1 173.8-107.9 128.5 -29.8 0.2 -14.4 54 67 A F E -CH 9 88C 0 -45,-2.6 -45,-3.9 -2,-0.5 2,-0.5 -0.916 21.8-137.9-124.0 154.2 -26.1 -0.6 -13.9 55 68 A V E -CH 8 87C 37 32,-3.0 32,-2.9 -2,-0.3 2,-2.1 -0.957 17.0-131.1-113.0 128.0 -24.4 -3.8 -12.6 56 69 A L E + H 0 86C 0 -49,-1.8 -50,-2.5 -2,-0.5 -49,-0.5 -0.548 38.4 171.6 -71.2 84.3 -21.5 -3.6 -10.2 57 70 A E E + 0 0 66 28,-2.1 2,-0.3 -2,-2.1 -1,-0.2 0.842 54.4 12.4 -70.0 -38.0 -19.4 -6.0 -12.3 58 71 A Q E - H 0 85C 88 27,-0.8 27,-1.4 -3,-0.2 2,-0.3 -0.949 50.1-167.9-141.7 158.5 -16.1 -5.7 -10.5 59 72 A S E + H 0 84C 20 -2,-0.3 2,-0.3 25,-0.2 25,-0.2 -0.859 23.3 156.1-149.3 113.9 -14.5 -4.5 -7.2 60 73 A L E - H 0 83C 42 23,-2.6 23,-3.2 -2,-0.3 2,-0.2 -0.857 42.1-101.8-131.6 165.6 -10.7 -4.2 -6.7 61 74 A S > - 0 0 43 -2,-0.3 4,-2.7 21,-0.2 5,-0.3 -0.590 34.6-116.3 -83.5 152.6 -8.2 -2.3 -4.6 62 75 A V H > S+ 0 0 53 19,-0.3 4,-2.3 1,-0.2 5,-0.2 0.904 117.9 49.6 -54.1 -43.5 -6.4 0.6 -6.2 63 76 A R H > S+ 0 0 71 2,-0.2 4,-1.5 1,-0.2 -1,-0.2 0.911 111.8 48.0 -62.7 -44.6 -3.1 -1.2 -5.8 64 77 A A H >> S+ 0 0 30 2,-0.2 4,-2.7 1,-0.2 3,-0.6 0.970 113.0 46.1 -60.7 -57.4 -4.5 -4.4 -7.4 65 78 A L H 3X S+ 0 0 6 -4,-2.7 4,-2.3 1,-0.3 5,-0.2 0.899 114.3 48.9 -51.8 -46.3 -6.0 -2.7 -10.4 66 79 A Q H 3X S+ 0 0 93 -4,-2.3 4,-1.3 -5,-0.3 -1,-0.3 0.751 110.8 51.4 -69.4 -24.5 -2.8 -0.7 -10.9 67 80 A E H X S+ 0 0 39 -4,-2.3 3,-1.0 -5,-0.2 4,-0.6 0.841 108.8 57.1 -69.9 -34.1 -2.6 -2.8 -15.6 70 83 A A H >< S+ 0 0 62 -4,-1.3 3,-0.6 1,-0.2 -1,-0.2 0.812 98.7 61.1 -66.9 -30.5 1.1 -2.4 -15.0 71 84 A N T 3< S+ 0 0 114 -4,-1.6 -1,-0.2 1,-0.2 -2,-0.2 0.663 99.8 56.6 -69.7 -16.5 1.7 -6.0 -16.1 72 85 A T T <4 0 0 109 -3,-1.0 -1,-0.2 -4,-0.4 -2,-0.2 0.691 360.0 360.0 -91.3 -21.3 0.3 -5.2 -19.5 73 86 A V << 0 0 165 -4,-0.6 -3,-0.0 -3,-0.6 -4,-0.0 -0.435 360.0 360.0 -65.0 360.0 2.7 -2.4 -20.5 74 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 75 110 A H 0 0 182 0, 0.0 -69,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 79.6 -20.3 -11.9 -5.2 76 111 A R - 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0 0 32 -5,-0.4 -5,-4.5 -6,-0.1 2,-0.4 -0.443 59.8-111.4 -95.4 173.8 -21.3 -1.0 -21.9 94 129 A Y E -JK 87 112C 35 18,-3.2 18,-1.2 -7,-0.3 -7,-0.2 -0.849 21.4-108.0-117.5 141.4 -19.5 0.7 -18.9 95 130 A L E + K 0 111C 0 -9,-2.3 2,-0.3 -2,-0.4 -9,-0.3 -0.440 52.8 175.2 -58.2 126.6 -19.7 4.0 -17.2 96 131 A C E - K 0 110C 0 14,-2.6 14,-1.9 -2,-0.2 2,-0.6 -0.939 38.3-119.8-139.9 159.0 -16.5 5.8 -18.1 97 132 A C E - K 0 109C 8 22,-2.5 12,-0.2 -2,-0.3 24,-0.1 -0.900 40.8-152.8-100.2 116.5 -14.7 9.2 -17.7 98 133 A L E - 0 0 42 10,-2.6 67,-0.0 -2,-0.6 -1,-0.0 -0.092 20.9-123.2 -87.6-178.3 -14.1 10.6 -21.2 99 134 A S E S+ 0 0 104 8,-0.1 2,-0.2 2,-0.1 -1,-0.1 0.682 83.6 86.4 -98.1 -24.0 -11.5 12.9 -22.7 100 135 A T E S- 0 0 81 8,-0.1 8,-2.7 1,-0.1 2,-0.2 -0.495 78.6-117.6 -80.9 150.7 -13.9 15.6 -24.1 101 136 A S E K 0 107C 63 6,-0.3 6,-0.3 -2,-0.2 -1,-0.1 -0.565 360.0 360.0 -92.4 151.2 -15.1 18.4 -21.9 102 137 A R 0 0 73 4,-1.6 3,-0.1 -2,-0.2 4,-0.1 -0.184 360.0 360.0 -67.1 360.0 -18.6 19.2 -20.9 103 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 104 142 A K 0 0 114 0, 0.0 -3,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -3.3 -15.3 23.4 -19.5 105 143 A L + 0 0 61 -3,-0.1 2,-0.2 -4,-0.1 0, 0.0 0.684 360.0 77.9 -83.4 -20.4 -13.0 22.3 -16.7 106 144 A A S S- 0 0 9 -4,-0.1 -4,-1.6 60,-0.1 60,-0.2 -0.514 76.9-129.3 -89.8 156.4 -15.0 19.1 -16.3 107 145 A F E -LK 165 101C 50 58,-2.5 58,-2.8 -6,-0.3 -6,-0.3 -0.629 28.1-101.2 -98.3 162.6 -14.9 16.0 -18.5 108 146 A D E -L 164 0C 30 -8,-2.7 -10,-2.6 -2,-0.2 2,-0.5 -0.563 26.6-141.8 -83.2 147.2 -17.9 14.2 -20.0 109 147 A V E + K 0 97C 1 54,-0.7 -73,-2.4 -2,-0.2 2,-0.2 -0.939 40.9 126.4-111.0 128.9 -19.3 11.0 -18.6 110 148 A G E -GK 35 96C 0 -14,-1.9 -14,-2.6 -2,-0.5 2,-0.3 -0.656 49.4 -73.2-152.4-153.9 -20.5 8.3 -20.9 111 149 A L E + K 0 95C 8 -77,-1.3 2,-0.3 -16,-0.2 -16,-0.2 -0.908 38.8 157.8-124.2 150.5 -20.4 4.7 -21.9 112 150 A Q E - 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