==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=12-JUL-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 13-MAY-13 4KP6 . COMPND 2 MOLECULE: CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.GEWALD,C.GRUNWALD,U.EGERLAND . 324 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15278.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 240 74.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 9 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 14.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 171 52.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 1 1 1 0 0 2 1 4 0 1 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 162 A N > 0 0 98 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 -48.9 -38.1 70.2 139.1 2 163 A E H > + 0 0 169 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.889 360.0 51.5 -61.4 -41.2 -39.9 72.4 141.6 3 164 A D H > S+ 0 0 144 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.907 110.3 48.5 -61.2 -43.2 -36.5 73.6 142.9 4 165 A H H > S+ 0 0 102 2,-0.2 4,-2.3 1,-0.2 -2,-0.2 0.911 112.4 48.3 -61.2 -43.8 -35.4 74.5 139.3 5 166 A L H X S+ 0 0 32 -4,-2.7 4,-2.4 2,-0.2 -2,-0.2 0.946 111.0 50.5 -62.9 -45.4 -38.7 76.4 138.7 6 167 A A H X S+ 0 0 50 -4,-2.6 4,-0.6 1,-0.2 -2,-0.2 0.886 109.1 52.9 -58.4 -39.9 -38.3 78.3 142.0 7 168 A K H >< S+ 0 0 145 -4,-2.2 3,-1.1 1,-0.2 4,-0.3 0.930 109.5 47.0 -63.2 -45.3 -34.8 79.2 141.0 8 169 A E H >< S+ 0 0 27 -4,-2.3 3,-1.9 1,-0.2 -1,-0.2 0.903 107.0 58.5 -62.0 -39.8 -35.9 80.6 137.6 9 170 A L H >< S+ 0 0 41 -4,-2.4 3,-2.0 1,-0.3 -1,-0.2 0.602 81.9 82.9 -72.3 -7.0 -38.7 82.5 139.4 10 171 A E T << S+ 0 0 139 -3,-1.1 3,-0.3 -4,-0.6 -1,-0.3 0.761 92.7 52.4 -58.8 -24.3 -36.1 84.3 141.5 11 172 A D T X S+ 0 0 49 -3,-1.9 3,-2.4 -4,-0.3 -1,-0.3 0.199 72.8 119.1 -97.4 17.5 -35.9 86.5 138.4 12 173 A L T < S+ 0 0 15 -3,-2.0 -1,-0.2 1,-0.3 -2,-0.1 0.810 81.1 40.4 -50.8 -38.0 -39.7 87.2 138.3 13 174 A N T 3 S+ 0 0 82 -3,-0.3 2,-0.4 -4,-0.2 -1,-0.3 0.200 104.2 92.0 -98.6 16.0 -39.2 90.9 138.7 14 175 A K S X S- 0 0 122 -3,-2.4 3,-1.2 0, 0.0 2,-0.2 -0.867 79.8-112.7-118.7 142.9 -36.2 91.2 136.3 15 176 A W T 3 S+ 0 0 49 -2,-0.4 -2,-0.1 1,-0.2 69,-0.0 -0.504 104.1 31.1 -62.8 135.1 -35.8 91.8 132.6 16 177 A G T 3 S+ 0 0 26 1,-0.2 -1,-0.2 -2,-0.2 2,-0.1 0.692 70.3 166.9 83.7 17.6 -34.5 88.6 131.1 17 178 A L < - 0 0 4 -3,-1.2 2,-1.5 -6,-0.3 -1,-0.2 -0.447 49.9-110.9 -48.7 136.0 -36.2 86.0 133.3 18 179 A N > + 0 0 21 -10,-0.2 4,-1.8 1,-0.2 3,-0.3 -0.609 43.2 175.0 -86.1 90.3 -35.6 82.8 131.2 19 180 A I H > S+ 0 0 2 -2,-1.5 4,-2.4 1,-0.2 -1,-0.2 0.763 75.8 63.7 -69.2 -24.9 -39.2 82.1 130.1 20 181 A F H > S+ 0 0 24 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.922 105.8 45.3 -62.0 -44.5 -38.0 79.2 128.0 21 182 A N H > S+ 0 0 60 -3,-0.3 4,-2.6 2,-0.2 -2,-0.2 0.900 109.6 54.9 -64.9 -40.9 -36.7 77.5 131.1 22 183 A V H X S+ 0 0 0 -4,-1.8 4,-1.3 2,-0.2 7,-0.3 0.909 107.2 51.1 -56.3 -43.4 -40.0 78.3 132.9 23 184 A A H <>S+ 0 0 6 -4,-2.4 5,-3.1 1,-0.2 6,-0.4 0.926 111.3 48.2 -59.3 -44.1 -41.9 76.6 130.0 24 185 A G H ><5S+ 0 0 49 -4,-2.0 3,-1.0 1,-0.2 -2,-0.2 0.925 114.5 43.4 -61.8 -46.0 -39.7 73.5 130.4 25 186 A Y H 3<5S+ 0 0 63 -4,-2.6 -1,-0.2 1,-0.2 -2,-0.2 0.588 112.7 52.7 -82.8 -9.8 -40.0 73.3 134.2 26 187 A S T 3<5S- 0 0 22 -4,-1.3 -1,-0.2 -3,-0.3 -2,-0.2 0.120 117.7-106.9-105.4 18.8 -43.8 73.9 134.1 27 188 A H T < 5S- 0 0 155 -3,-1.0 -3,-0.2 1,-0.2 -2,-0.1 0.915 79.9 -48.6 45.8 55.4 -44.5 71.2 131.6 28 189 A N S + 0 0 83 -6,-0.4 4,-2.6 -7,-0.3 5,-0.2 -0.379 24.6 145.6-125.2 54.5 -47.5 75.9 130.8 30 191 A P H > S+ 0 0 1 0, 0.0 4,-2.6 0, 0.0 5,-0.2 0.834 70.6 51.2 -63.7 -32.9 -45.4 79.1 130.9 31 192 A L H > S+ 0 0 0 2,-0.2 4,-2.4 3,-0.2 5,-0.2 0.951 114.1 41.2 -72.3 -49.1 -48.4 81.4 130.7 32 193 A T H > S+ 0 0 16 2,-0.2 4,-2.3 1,-0.2 5,-0.2 0.940 118.9 48.3 -59.2 -46.8 -50.4 79.9 133.5 33 194 A C H X S+ 0 0 25 -4,-2.6 4,-2.4 1,-0.2 -2,-0.2 0.956 115.6 41.3 -60.7 -52.8 -47.2 79.5 135.6 34 195 A I H X S+ 0 0 0 -4,-2.6 4,-2.8 -5,-0.2 -1,-0.2 0.875 114.5 51.8 -68.3 -37.2 -45.9 83.0 135.1 35 196 A M H X S+ 0 0 0 -4,-2.4 4,-2.7 -5,-0.2 5,-0.2 0.902 110.3 48.6 -65.8 -39.7 -49.3 84.7 135.5 36 197 A Y H X S+ 0 0 63 -4,-2.3 4,-2.5 -5,-0.2 5,-0.2 0.950 113.4 48.3 -63.0 -46.2 -50.0 82.8 138.8 37 198 A A H X S+ 0 0 12 -4,-2.4 4,-2.8 -5,-0.2 -2,-0.2 0.922 113.7 46.6 -57.7 -47.1 -46.5 83.9 139.9 38 199 A I H X S+ 0 0 0 -4,-2.8 4,-2.3 1,-0.2 6,-0.3 0.902 113.2 48.2 -63.2 -44.8 -47.1 87.6 138.9 39 200 A F H <>S+ 0 0 0 -4,-2.7 5,-1.7 2,-0.2 6,-0.9 0.865 114.1 46.5 -69.9 -34.2 -50.5 87.7 140.5 40 201 A Q H ><5S+ 0 0 108 -4,-2.5 3,-1.4 -5,-0.2 -2,-0.2 0.947 112.1 51.9 -64.4 -47.8 -49.2 86.2 143.7 41 202 A E H 3<5S+ 0 0 95 -4,-2.8 -2,-0.2 1,-0.3 -1,-0.2 0.862 114.9 40.2 -57.5 -43.0 -46.2 88.6 143.7 42 203 A R T 3<5S- 0 0 51 -4,-2.3 -1,-0.3 -5,-0.1 -2,-0.2 0.351 107.2-122.5 -90.8 6.4 -48.4 91.7 143.3 43 204 A D T <>5 + 0 0 84 -3,-1.4 4,-3.0 -4,-0.2 -3,-0.2 0.755 64.9 144.3 57.9 26.3 -51.1 90.4 145.7 44 205 A L H >< + 0 0 5 -5,-1.7 4,-2.3 -6,-0.3 6,-0.2 0.842 65.2 54.7 -67.8 -33.7 -53.5 90.8 142.8 45 206 A L H 4>S+ 0 0 19 -6,-0.9 5,-2.2 2,-0.2 4,-0.5 0.918 114.7 40.9 -63.3 -44.2 -55.6 87.8 143.9 46 207 A K H >45S+ 0 0 165 -7,-0.3 3,-0.5 3,-0.2 -2,-0.2 0.942 116.9 47.8 -66.2 -48.3 -56.0 89.3 147.3 47 208 A T H 3<5S+ 0 0 69 -4,-3.0 -2,-0.2 1,-0.2 -3,-0.2 0.899 122.4 33.3 -62.0 -41.3 -56.6 92.9 146.2 48 209 A F T 3<5S- 0 0 15 -4,-2.3 116,-0.4 -5,-0.2 -1,-0.2 0.321 108.1-121.8-104.0 5.8 -59.2 92.0 143.5 49 210 A R T < 5 + 0 0 176 -3,-0.5 2,-0.5 -4,-0.5 -3,-0.2 0.911 52.6 160.5 56.9 54.3 -60.6 89.0 145.5 50 211 A I < - 0 0 11 -5,-2.2 -1,-0.2 -6,-0.2 2,-0.1 -0.917 36.2-131.1-108.0 124.2 -59.9 86.4 142.8 51 212 A S > - 0 0 60 -2,-0.5 4,-2.5 1,-0.1 5,-0.2 -0.451 16.4-123.5 -72.6 151.9 -59.9 82.8 144.0 52 213 A S H > S+ 0 0 46 1,-0.2 4,-2.9 2,-0.2 5,-0.3 0.868 113.2 56.9 -59.7 -36.6 -56.9 80.7 142.9 53 214 A D H > S+ 0 0 97 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.929 109.7 42.5 -59.9 -49.6 -59.4 78.3 141.4 54 215 A T H > S+ 0 0 24 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.926 116.4 48.7 -64.7 -45.2 -61.0 80.9 139.2 55 216 A F H X S+ 0 0 1 -4,-2.5 4,-2.8 1,-0.2 -2,-0.2 0.929 114.1 43.1 -63.6 -47.0 -57.7 82.4 138.2 56 217 A I H X S+ 0 0 53 -4,-2.9 4,-2.3 2,-0.2 -1,-0.2 0.837 113.3 53.9 -70.3 -30.4 -56.0 79.1 137.3 57 218 A T H X S+ 0 0 36 -4,-2.0 4,-1.9 -5,-0.3 -2,-0.2 0.953 113.1 42.9 -65.3 -48.9 -59.2 77.9 135.4 58 219 A Y H X S+ 0 0 0 -4,-2.6 4,-3.0 100,-0.4 -2,-0.2 0.944 115.3 49.2 -59.8 -52.0 -59.2 81.1 133.3 59 220 A M H X S+ 0 0 1 -4,-2.8 4,-2.7 1,-0.2 -1,-0.2 0.876 110.3 48.9 -59.7 -41.6 -55.4 81.0 132.7 60 221 A M H X S+ 0 0 66 -4,-2.3 4,-1.9 2,-0.2 -1,-0.2 0.880 114.0 47.1 -64.6 -38.2 -55.4 77.4 131.7 61 222 A T H X S+ 0 0 34 -4,-1.9 4,-0.9 2,-0.2 -2,-0.2 0.921 112.8 49.3 -67.6 -43.7 -58.3 78.0 129.3 62 223 A L H >< S+ 0 0 0 -4,-3.0 3,-1.0 1,-0.2 4,-0.3 0.939 111.6 48.9 -57.3 -48.3 -56.6 81.1 127.9 63 224 A E H >< S+ 0 0 9 -4,-2.7 3,-1.5 1,-0.3 -1,-0.2 0.882 105.9 57.1 -63.6 -37.8 -53.3 79.2 127.4 64 225 A D H 3< S+ 0 0 101 -4,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.700 100.7 60.1 -63.2 -22.5 -55.2 76.4 125.6 65 226 A H T << S+ 0 0 70 -3,-1.0 51,-1.2 -4,-0.9 2,-0.4 0.431 84.6 88.4 -91.9 -0.8 -56.4 79.1 123.2 66 227 A Y S < S- 0 0 9 -3,-1.5 2,-0.6 -4,-0.3 8,-0.2 -0.828 91.7-116.5 -85.5 135.9 -52.9 79.9 122.1 67 228 A H > - 0 0 58 6,-0.5 3,-1.2 -2,-0.4 -2,-0.1 -0.652 19.8-160.0 -81.4 119.4 -52.0 77.6 119.2 68 229 A S T 3 S+ 0 0 118 -2,-0.6 -1,-0.1 1,-0.2 6,-0.1 0.706 88.6 61.9 -70.5 -19.6 -49.1 75.3 120.2 69 230 A D T 3 S+ 0 0 128 -3,-0.0 2,-0.4 5,-0.0 -1,-0.2 0.407 81.7 91.1 -89.9 0.7 -48.4 74.6 116.5 70 231 A V S < S- 0 0 12 -3,-1.2 49,-0.1 1,-0.1 182,-0.1 -0.829 75.0-139.2 -92.8 138.0 -47.5 78.2 115.6 71 232 A A S S+ 0 0 22 -2,-0.4 178,-0.1 177,-0.1 3,-0.1 0.821 87.1 7.8 -71.2 -33.5 -43.8 78.9 116.0 72 233 A Y S S+ 0 0 13 176,-0.2 2,-2.2 177,-0.1 5,-0.5 0.791 116.7 63.0-113.2 -53.2 -43.9 82.3 117.7 73 234 A H S S+ 0 0 28 175,-0.1 -6,-0.5 4,-0.1 44,-0.4 -0.236 80.2 113.2 -83.6 53.3 -47.4 83.5 118.6 74 235 A N S >> S- 0 0 16 -2,-2.2 4,-1.4 -8,-0.2 3,-0.8 -0.440 89.8 -80.0-111.0-176.6 -48.0 80.7 121.1 75 236 A S H 3> S+ 0 0 17 1,-0.3 4,-2.5 -12,-0.2 5,-0.2 0.717 123.9 66.5 -69.6 -16.4 -48.3 80.9 124.9 76 237 A L H 3> S+ 0 0 9 2,-0.2 4,-2.3 1,-0.2 -1,-0.3 0.903 103.1 47.5 -63.9 -43.1 -44.5 81.2 125.5 77 238 A H H <> S+ 0 0 0 -3,-0.8 4,-2.6 -5,-0.5 -2,-0.2 0.919 112.1 49.7 -62.2 -44.9 -44.7 84.6 123.7 78 239 A A H X S+ 0 0 0 -4,-1.4 4,-2.7 2,-0.2 -2,-0.2 0.922 110.6 49.7 -59.1 -45.0 -47.7 85.6 125.8 79 240 A A H X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 5,-0.2 0.916 111.3 49.9 -61.0 -43.2 -45.9 84.6 129.0 80 241 A D H X S+ 0 0 2 -4,-2.3 4,-2.6 2,-0.2 -2,-0.2 0.921 111.9 46.9 -61.3 -47.1 -42.8 86.6 127.9 81 242 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 2,-0.2 -2,-0.2 0.909 113.3 49.3 -66.7 -39.0 -44.9 89.8 127.2 82 243 A A H X S+ 0 0 0 -4,-2.7 4,-2.4 28,-0.3 -2,-0.2 0.930 113.4 44.8 -63.9 -47.8 -46.8 89.5 130.4 83 244 A Q H X S+ 0 0 0 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.903 114.1 50.4 -64.8 -38.5 -43.6 89.0 132.5 84 245 A S H X S+ 0 0 0 -4,-2.6 4,-2.5 -5,-0.2 -2,-0.2 0.907 110.6 49.3 -66.9 -37.7 -42.0 91.9 130.6 85 246 A T H X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 -2,-0.2 0.926 107.7 54.7 -65.1 -43.8 -45.0 94.1 131.2 86 247 A H H X S+ 0 0 1 -4,-2.4 4,-0.7 2,-0.2 -2,-0.2 0.905 110.1 47.2 -54.0 -42.1 -44.9 93.2 134.9 87 248 A V H >< S+ 0 0 22 -4,-2.0 3,-1.0 1,-0.2 -2,-0.2 0.951 110.7 51.0 -65.4 -48.0 -41.2 94.4 134.9 88 249 A L H >< S+ 0 0 6 -4,-2.5 3,-1.8 1,-0.3 -2,-0.2 0.858 102.2 60.5 -59.6 -37.5 -42.0 97.7 133.1 89 250 A L H 3< S+ 0 0 13 -4,-2.5 -1,-0.3 1,-0.3 9,-0.2 0.793 105.2 50.1 -62.9 -26.9 -44.8 98.5 135.6 90 251 A S T << S+ 0 0 67 -3,-1.0 -1,-0.3 -4,-0.7 -2,-0.2 0.188 74.4 136.1 -95.9 14.8 -42.2 98.5 138.4 91 252 A T X - 0 0 17 -3,-1.8 3,-2.4 1,-0.1 214,-0.0 -0.470 62.5-126.1 -62.9 130.1 -39.7 100.8 136.7 92 253 A P G > S+ 0 0 84 0, 0.0 3,-2.1 0, 0.0 -1,-0.1 0.834 107.2 63.3 -51.6 -37.7 -38.6 103.2 139.5 93 254 A A G 3 S+ 0 0 6 208,-0.3 118,-3.0 1,-0.3 -2,-0.1 0.655 103.7 50.8 -60.9 -15.2 -39.4 106.3 137.4 94 255 A L G X> S+ 0 0 3 -3,-2.4 3,-2.2 116,-0.2 4,-0.6 0.129 78.7 152.6-107.3 19.0 -43.1 105.1 137.5 95 256 A D T <4 S- 0 0 112 -3,-2.1 -5,-0.1 1,-0.3 -6,-0.0 -0.289 78.2 -11.0 -55.8 119.6 -43.2 104.7 141.3 96 257 A A T 34 S+ 0 0 94 2,-0.1 -1,-0.3 1,-0.1 -2,-0.0 0.599 104.2 115.4 66.3 15.4 -46.8 105.1 142.6 97 258 A V T <4 + 0 0 16 -3,-2.2 2,-0.3 2,-0.1 -2,-0.1 0.939 64.6 57.4 -79.0 -47.5 -47.9 106.5 139.2 98 259 A F S < S- 0 0 18 -4,-0.6 -2,-0.1 -9,-0.2 2,-0.0 -0.604 79.3-126.7 -96.5 145.6 -50.4 103.7 138.2 99 260 A T > - 0 0 66 -2,-0.3 4,-2.2 1,-0.1 5,-0.1 -0.274 30.1-106.1 -77.3 166.5 -53.4 102.4 140.1 100 261 A D H > S+ 0 0 94 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.889 123.3 53.1 -57.7 -40.4 -54.0 98.8 141.1 101 262 A L H > S+ 0 0 22 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.882 108.1 49.2 -64.4 -41.6 -56.6 98.7 138.4 102 263 A E H > S+ 0 0 7 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.890 111.4 50.0 -62.3 -41.7 -54.2 99.9 135.8 103 264 A I H X S+ 0 0 25 -4,-2.2 4,-2.1 2,-0.2 5,-0.2 0.945 112.8 46.5 -60.0 -52.3 -51.6 97.3 136.9 104 265 A L H X S+ 0 0 0 -4,-2.6 4,-2.5 1,-0.2 5,-0.2 0.921 113.4 49.4 -54.3 -48.6 -54.2 94.6 136.7 105 266 A A H X S+ 0 0 0 -4,-2.6 4,-3.0 1,-0.2 -2,-0.2 0.905 110.7 49.2 -61.3 -45.1 -55.4 95.8 133.2 106 267 A A H X S+ 0 0 0 -4,-2.4 4,-2.4 2,-0.2 -1,-0.2 0.908 113.2 45.2 -64.8 -44.0 -51.9 96.0 131.8 107 268 A I H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 -1,-0.2 0.917 115.5 47.5 -68.5 -43.1 -50.8 92.5 132.9 108 269 A F H X S+ 0 0 0 -4,-2.5 4,-2.2 -5,-0.2 -2,-0.2 0.936 110.7 52.1 -60.2 -47.7 -54.1 91.0 131.7 109 270 A A H X S+ 0 0 0 -4,-3.0 4,-1.3 1,-0.2 -2,-0.2 0.941 109.7 49.7 -53.2 -49.0 -53.8 92.8 128.4 110 271 A A H < S+ 0 0 0 -4,-2.4 3,-0.4 1,-0.2 -28,-0.3 0.902 110.4 50.6 -57.3 -43.2 -50.3 91.4 128.0 111 272 A A H < S+ 0 0 0 -4,-2.2 3,-0.3 1,-0.2 -1,-0.2 0.871 121.0 32.2 -65.0 -38.9 -51.5 87.9 128.8 112 273 A I H >< S+ 0 0 0 -4,-2.2 3,-2.0 1,-0.2 -1,-0.2 0.471 87.3 106.1 -92.1 -7.5 -54.4 87.9 126.2 113 274 A H T 3< S+ 0 0 0 -4,-1.3 33,-0.2 -3,-0.4 -1,-0.2 0.610 93.3 22.9 -65.9 -17.5 -52.8 90.2 123.6 114 275 A D T > S+ 0 0 6 -3,-0.3 3,-1.1 -4,-0.3 -1,-0.3 0.117 84.7 150.5-125.6 23.5 -52.1 87.4 121.0 115 276 A V T < S+ 0 0 0 -3,-2.0 -49,-0.2 1,-0.2 34,-0.2 -0.200 71.2 9.5 -65.5 141.2 -54.6 84.7 122.0 116 277 A D T 3 S+ 0 0 45 -51,-1.2 -1,-0.2 -54,-0.2 -50,-0.2 0.835 85.3 172.4 61.7 35.1 -55.9 82.5 119.2 117 278 A H < - 0 0 8 -3,-1.1 -50,-0.4 -44,-0.4 -1,-0.2 -0.595 28.7-149.7 -73.7 131.5 -53.4 83.9 116.8 118 279 A P - 0 0 44 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.491 40.0-109.8 -82.7 -3.4 -53.4 82.0 113.5 119 280 A G S S+ 0 0 8 1,-0.3 2,-0.3 -46,-0.1 137,-0.1 0.675 87.0 97.0 80.0 21.4 -49.7 82.6 112.7 120 281 A V S S- 0 0 8 136,-0.1 -1,-0.3 135,-0.1 133,-0.1 -0.926 72.8-103.8-132.3 163.5 -50.2 85.0 109.8 121 282 A S > - 0 0 36 -2,-0.3 4,-2.1 -3,-0.1 5,-0.2 -0.255 26.5-109.5 -84.3 166.7 -50.3 88.8 109.6 122 283 A N H > S+ 0 0 26 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.905 120.5 56.0 -55.8 -42.0 -53.1 91.3 109.4 123 284 A Q H > S+ 0 0 121 1,-0.2 4,-2.8 2,-0.2 -1,-0.2 0.910 106.8 49.8 -62.0 -40.6 -52.0 92.0 105.8 124 285 A F H > S+ 0 0 17 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.916 111.0 48.4 -60.8 -44.6 -52.4 88.3 104.9 125 286 A L H <>S+ 0 0 10 -4,-2.1 5,-2.5 2,-0.2 8,-0.3 0.873 114.6 46.8 -65.0 -38.0 -55.9 88.2 106.5 126 287 A I H ><5S+ 0 0 44 -4,-2.6 3,-1.5 1,-0.2 -2,-0.2 0.947 113.1 46.9 -66.8 -50.6 -56.9 91.3 104.5 127 288 A N H 3<5S+ 0 0 99 -4,-2.8 -2,-0.2 1,-0.3 -1,-0.2 0.697 112.7 49.8 -71.2 -17.5 -55.5 90.2 101.2 128 289 A T T 3<5S- 0 0 24 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.298 110.4-120.1 -99.1 9.0 -57.1 86.7 101.5 129 290 A N T < 5 - 0 0 144 -3,-1.5 -3,-0.2 1,-0.1 -2,-0.1 0.878 43.0-168.6 54.7 43.3 -60.5 88.2 102.4 130 291 A S >< - 0 0 26 -5,-2.5 4,-2.4 -6,-0.2 5,-0.2 -0.256 32.8-120.1 -56.8 146.0 -60.6 86.4 105.7 131 292 A E H > S+ 0 0 118 1,-0.2 4,-2.7 2,-0.2 5,-0.1 0.863 117.6 55.3 -51.0 -39.0 -63.8 86.3 107.7 132 293 A L H > S+ 0 0 33 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.903 106.3 48.8 -66.0 -41.9 -61.9 88.1 110.5 133 294 A A H 4>S+ 0 0 2 -8,-0.3 5,-2.4 1,-0.2 4,-0.4 0.902 113.4 48.6 -62.9 -40.0 -60.9 90.9 108.1 134 295 A L H ><5S+ 0 0 115 -4,-2.4 3,-1.0 3,-0.2 -2,-0.2 0.922 109.8 51.4 -59.6 -50.9 -64.6 91.2 107.0 135 296 A M H 3<5S+ 0 0 106 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.877 120.8 33.0 -54.8 -42.4 -65.8 91.3 110.6 136 297 A Y T ><5S- 0 0 58 -4,-1.9 3,-2.2 -5,-0.1 -1,-0.2 0.193 106.3-118.1-107.5 18.3 -63.5 94.1 111.6 137 298 A N T < 5 - 0 0 137 -3,-1.0 -3,-0.2 -4,-0.4 -4,-0.1 0.884 69.0 -63.8 45.8 47.1 -63.3 96.0 108.3 138 299 A D T 3 S+ 0 0 6 -2,-0.6 4,-3.1 3,-0.1 5,-0.3 0.884 82.8 178.0 38.6 55.8 -56.6 95.9 113.7 141 302 A V H > + 0 0 0 -3,-0.3 4,-1.9 1,-0.2 5,-0.1 0.927 70.0 35.4 -63.4 -56.7 -58.0 92.6 112.6 142 303 A L H > S+ 0 0 7 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.886 117.1 53.9 -59.3 -45.0 -55.9 90.2 114.7 143 304 A E H > S+ 0 0 12 2,-0.2 4,-2.1 1,-0.2 -2,-0.2 0.911 108.4 49.0 -64.2 -41.6 -55.9 92.5 117.7 144 305 A N H X S+ 0 0 40 -4,-3.1 4,-2.5 -5,-0.2 -1,-0.2 0.906 112.1 50.3 -57.4 -42.7 -59.7 92.8 117.7 145 306 A H H X S+ 0 0 25 -4,-1.9 4,-2.5 -5,-0.3 5,-0.2 0.898 107.0 52.6 -64.8 -42.4 -59.9 89.1 117.5 146 307 A H H X S+ 0 0 0 -4,-2.7 4,-2.9 1,-0.2 5,-0.2 0.929 111.7 47.4 -58.9 -45.4 -57.5 88.6 120.5 147 308 A L H X S+ 0 0 8 -4,-2.1 4,-2.6 2,-0.2 5,-0.3 0.915 109.9 53.3 -60.0 -45.3 -59.7 90.9 122.5 148 309 A A H X S+ 0 0 42 -4,-2.5 4,-2.0 1,-0.2 -2,-0.2 0.929 115.5 38.7 -58.8 -47.0 -62.8 89.0 121.4 149 310 A V H X S+ 0 0 23 -4,-2.5 4,-2.2 2,-0.2 -2,-0.2 0.940 115.4 51.0 -70.7 -46.9 -61.5 85.7 122.5 150 311 A G H X S+ 0 0 0 -4,-2.9 4,-0.5 -5,-0.2 -2,-0.2 0.904 116.0 42.1 -61.9 -40.5 -59.7 86.8 125.7 151 312 A F H >< S+ 0 0 12 -4,-2.6 3,-1.0 -5,-0.2 4,-0.4 0.880 110.9 54.5 -71.5 -41.3 -62.9 88.6 126.9 152 313 A K H >< S+ 0 0 115 -4,-2.0 3,-1.8 -5,-0.3 4,-0.2 0.860 98.7 63.3 -65.2 -33.0 -65.3 85.8 125.9 153 314 A L H >< S+ 0 0 9 -4,-2.2 3,-1.5 1,-0.3 -1,-0.3 0.778 89.2 69.9 -62.1 -24.7 -63.3 83.3 127.9 154 315 A L T << S+ 0 0 17 -3,-1.0 5,-0.3 -4,-0.5 -1,-0.3 0.738 92.7 59.5 -60.3 -25.7 -64.2 85.3 131.1 155 316 A Q T < S+ 0 0 125 -3,-1.8 -1,-0.2 -4,-0.4 -2,-0.2 0.493 82.4 105.1 -83.6 -5.8 -67.8 84.0 130.6 156 317 A E S X S- 0 0 100 -3,-1.5 3,-1.9 -4,-0.2 4,-0.3 -0.332 92.3 -71.3 -71.8 158.2 -66.9 80.3 130.8 157 318 A E T 3 S- 0 0 159 1,-0.3 -1,-0.2 2,-0.1 -2,-0.1 -0.272 117.7 -3.4 -57.6 128.0 -67.7 78.5 134.0 158 319 A H T 3 S+ 0 0 127 -3,-0.1 -100,-0.4 1,-0.1 -1,-0.3 0.736 108.0 106.3 60.4 31.0 -65.5 79.6 136.9 159 320 A C < + 0 0 1 -3,-1.9 2,-1.8 -5,-0.3 -2,-0.1 0.494 33.9 108.2-113.7 -8.4 -63.5 81.9 134.6 160 321 A D > + 0 0 33 -4,-0.3 3,-1.6 1,-0.2 -105,-0.1 -0.536 35.4 172.9 -82.0 86.4 -64.6 85.5 135.5 161 322 A I T 3 S+ 0 0 4 -2,-1.8 3,-0.3 1,-0.2 -1,-0.2 0.593 76.4 56.0 -65.7 -13.2 -61.5 86.7 137.3 162 323 A F T > + 0 0 7 1,-0.1 3,-1.7 -8,-0.1 -1,-0.2 0.291 69.6 112.5-101.4 10.4 -63.1 90.2 137.4 163 324 A M T < S+ 0 0 125 -3,-1.6 -1,-0.1 1,-0.3 -2,-0.1 0.707 79.0 46.4 -57.3 -27.3 -66.3 89.3 139.2 164 325 A N T 3 S+ 0 0 90 -116,-0.4 -1,-0.3 -3,-0.3 2,-0.1 0.385 86.4 106.7-104.0 3.5 -65.4 91.2 142.4 165 326 A L S < S- 0 0 11 -3,-1.7 -117,-0.0 1,-0.1 -3,-0.0 -0.438 82.5-100.7 -65.3 151.2 -64.3 94.4 140.7 166 327 A T > - 0 0 75 -2,-0.1 4,-2.7 1,-0.1 5,-0.2 -0.318 33.9-106.1 -67.0 162.7 -66.8 97.3 141.1 167 328 A K H > S+ 0 0 190 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.928 123.2 46.9 -58.6 -45.6 -69.0 98.0 138.1 168 329 A K H > S+ 0 0 135 1,-0.2 4,-2.8 2,-0.2 -1,-0.2 0.866 111.2 51.8 -65.2 -37.4 -67.0 101.1 137.2 169 330 A Q H > S+ 0 0 70 2,-0.2 4,-2.9 1,-0.2 5,-0.2 0.899 109.0 50.3 -66.6 -39.8 -63.8 99.2 137.6 170 331 A R H X S+ 0 0 103 -4,-2.7 4,-2.4 2,-0.2 -2,-0.2 0.947 113.6 45.4 -60.1 -47.0 -65.0 96.5 135.3 171 332 A Q H X S+ 0 0 114 -4,-2.4 4,-2.1 2,-0.2 -2,-0.2 0.927 116.2 45.4 -61.1 -47.1 -66.0 99.1 132.7 172 333 A T H X S+ 0 0 27 -4,-2.8 4,-2.8 2,-0.2 5,-0.2 0.919 112.4 50.4 -67.0 -43.5 -62.7 101.0 133.0 173 334 A L H X S+ 0 0 4 -4,-2.9 4,-3.0 -5,-0.2 5,-0.3 0.930 108.8 53.1 -61.4 -40.9 -60.6 97.9 132.9 174 335 A R H X S+ 0 0 124 -4,-2.4 4,-2.4 -5,-0.2 -2,-0.2 0.945 111.4 45.6 -57.1 -49.5 -62.4 96.7 129.8 175 336 A K H X S+ 0 0 107 -4,-2.1 4,-2.5 1,-0.2 -1,-0.2 0.903 114.8 48.1 -59.7 -46.4 -61.6 100.1 128.1 176 337 A M H X S+ 0 0 2 -4,-2.8 4,-2.3 2,-0.2 -2,-0.2 0.895 110.9 49.6 -63.8 -43.0 -58.0 100.0 129.2 177 338 A V H X S+ 0 0 0 -4,-3.0 4,-2.8 2,-0.2 5,-0.3 0.928 111.2 50.4 -61.3 -45.1 -57.4 96.4 128.1 178 339 A I H X S+ 0 0 49 -4,-2.4 4,-2.7 -5,-0.3 5,-0.3 0.954 110.2 50.3 -55.3 -50.8 -58.8 97.2 124.7 179 340 A D H X S+ 0 0 36 -4,-2.5 4,-1.5 1,-0.2 -1,-0.2 0.913 113.5 44.7 -55.4 -43.5 -56.6 100.3 124.5 180 341 A M H < S+ 0 0 0 -4,-2.3 -1,-0.2 2,-0.2 -2,-0.2 0.898 114.7 46.4 -75.7 -37.6 -53.4 98.2 125.3 181 342 A V H >< S+ 0 0 0 -4,-2.8 3,-1.8 1,-0.2 4,-0.2 0.924 112.8 50.1 -70.4 -43.0 -54.2 95.2 123.1 182 343 A L H >< S+ 0 0 36 -4,-2.7 3,-1.9 -5,-0.3 -1,-0.2 0.849 100.1 66.7 -62.1 -29.5 -55.1 97.5 120.1 183 344 A A T 3< S+ 0 0 2 -4,-1.5 -1,-0.3 -5,-0.3 -2,-0.2 0.542 89.0 66.8 -68.8 -7.8 -51.8 99.4 120.8 184 345 A T T < S+ 0 0 4 -3,-1.8 2,-0.6 -4,-0.2 -1,-0.3 0.525 73.2 107.5 -86.8 -8.6 -50.0 96.2 119.7 185 346 A D X - 0 0 9 -3,-1.9 3,-2.5 -4,-0.2 4,-0.3 -0.602 69.6-144.3 -65.4 116.3 -51.3 96.7 116.1 186 347 A M G > S+ 0 0 77 -2,-0.6 3,-1.4 1,-0.3 4,-0.4 0.757 95.4 71.2 -59.6 -23.8 -48.2 97.7 114.2 187 348 A S G 3 S+ 0 0 104 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.728 98.6 50.6 -61.2 -19.9 -50.3 100.1 112.1 188 349 A K G <> S+ 0 0 73 -3,-2.5 4,-2.6 -6,-0.2 -1,-0.2 0.431 83.3 98.2 -93.7 -3.1 -50.6 102.3 115.3 189 350 A H H <> S+ 0 0 2 -3,-1.4 4,-2.7 -4,-0.3 5,-0.2 0.885 80.5 47.3 -58.2 -48.7 -46.9 102.3 115.9 190 351 A M H > S+ 0 0 125 -4,-0.4 4,-2.1 2,-0.2 -1,-0.2 0.885 114.7 47.7 -63.0 -38.0 -46.0 105.7 114.4 191 352 A S H > S+ 0 0 76 -4,-0.2 4,-2.1 2,-0.2 -2,-0.2 0.924 112.3 48.5 -66.2 -47.7 -48.9 107.4 116.2 192 353 A L H X S+ 0 0 11 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.918 113.4 47.8 -57.3 -47.4 -48.1 105.8 119.5 193 354 A L H X S+ 0 0 11 -4,-2.7 4,-2.7 -5,-0.2 -1,-0.2 0.881 108.5 53.8 -65.5 -39.1 -44.4 106.8 119.1 194 355 A A H X S+ 0 0 49 -4,-2.1 4,-2.1 -5,-0.2 -1,-0.2 0.921 111.6 45.9 -59.5 -42.8 -45.3 110.4 118.1 195 356 A D H X S+ 0 0 63 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.903 111.5 51.8 -68.0 -40.7 -47.4 110.6 121.3 196 357 A L H X S+ 0 0 0 -4,-2.5 4,-2.3 2,-0.2 -2,-0.2 0.924 109.6 49.9 -60.3 -43.2 -44.6 109.1 123.4 197 358 A K H X S+ 0 0 87 -4,-2.7 4,-2.7 1,-0.2 -1,-0.2 0.894 108.9 52.6 -62.6 -42.0 -42.1 111.6 122.0 198 359 A T H X S+ 0 0 74 -4,-2.1 4,-1.3 2,-0.2 -1,-0.2 0.904 108.5 50.4 -58.7 -42.4 -44.6 114.4 122.8 199 360 A M H < S+ 0 0 17 -4,-2.2 -2,-0.2 2,-0.2 3,-0.2 0.906 111.3 48.3 -64.4 -39.1 -44.8 113.2 126.4 200 361 A V H >< S+ 0 0 30 -4,-2.3 3,-1.3 1,-0.2 -2,-0.2 0.929 110.5 51.0 -64.2 -45.8 -40.9 113.1 126.6 201 362 A E H 3< S+ 0 0 150 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.728 122.6 32.0 -63.9 -25.7 -40.7 116.7 125.2 202 363 A T T 3< S+ 0 0 94 -4,-1.3 -1,-0.3 -3,-0.2 -2,-0.2 0.056 88.3 151.9-116.6 23.9 -43.3 117.9 127.8 203 364 A K < - 0 0 67 -3,-1.3 2,-0.4 -5,-0.1 -3,-0.1 -0.230 30.4-156.1 -70.1 142.5 -42.4 115.6 130.7 204 365 A K - 0 0 126 8,-0.5 8,-2.8 -5,-0.0 2,-0.3 -0.954 14.6-174.0-113.9 138.7 -43.0 116.7 134.3 205 366 A V B -A 211 0A 68 -2,-0.4 6,-0.2 6,-0.2 -112,-0.0 -0.985 19.0-125.0-138.1 140.5 -41.0 115.0 137.1 206 367 A T > - 0 0 47 4,-2.7 3,-1.5 -2,-0.3 6,-0.0 -0.192 39.7 -96.5 -71.8 172.2 -41.0 115.1 140.9 207 368 A S T 3 S+ 0 0 137 1,-0.2 -1,-0.1 2,-0.1 -2,-0.0 0.833 126.0 57.3 -55.3 -35.0 -38.0 116.0 143.1 208 369 A S T 3 S- 0 0 90 2,-0.1 -1,-0.2 1,-0.0 -2,-0.0 0.423 122.7-103.2 -79.6 -1.3 -37.4 112.2 143.5 209 370 A G S < S+ 0 0 38 -3,-1.5 2,-0.4 1,-0.3 -2,-0.1 0.654 74.8 141.4 87.2 18.6 -37.1 111.6 139.7 210 371 A V - 0 0 17 -116,-0.1 -4,-2.7 1,-0.1 -1,-0.3 -0.761 55.0-110.3 -98.6 137.8 -40.7 110.1 139.3 211 372 A L B -A 205 0A 8 -118,-3.0 2,-0.6 -2,-0.4 -6,-0.2 -0.383 22.4-139.0 -66.7 137.1 -42.9 110.9 136.3 212 373 A L + 0 0 84 -8,-2.8 -8,-0.5 -2,-0.1 2,-0.3 -0.913 23.4 176.1 -99.6 115.0 -46.0 113.1 136.8 213 374 A L + 0 0 17 -2,-0.6 6,-0.1 1,-0.2 -2,-0.0 -0.643 8.8 164.0-124.6 67.8 -49.0 111.7 134.9 214 375 A D + 0 0 101 -2,-0.3 -1,-0.2 4,-0.1 2,-0.1 0.953 53.5 51.4 -39.4 -78.1 -51.9 114.0 135.8 215 376 A N S > S- 0 0 71 1,-0.1 4,-1.7 4,-0.0 3,-0.4 -0.349 81.3-120.0 -85.3 154.4 -54.6 113.4 133.2 216 377 A Y H > S+ 0 0 102 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.775 109.9 60.8 -60.9 -34.0 -56.0 110.1 132.1 217 378 A T H > S+ 0 0 86 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.933 106.4 46.3 -60.4 -47.3 -54.9 110.6 128.4 218 379 A D H > S+ 0 0 41 -3,-0.4 4,-2.3 2,-0.2 -2,-0.2 0.904 112.6 52.0 -59.9 -41.0 -51.3 110.8 129.5 219 380 A R H X S+ 0 0 41 -4,-1.7 4,-2.2 2,-0.2 -2,-0.2 0.932 112.8 41.8 -62.9 -49.4 -51.7 107.7 131.7 220 381 A I H X S+ 0 0 5 -4,-2.6 4,-2.8 2,-0.2 -1,-0.2 0.836 111.1 57.5 -71.7 -29.4 -53.2 105.5 129.0 221 382 A Q H X S+ 0 0 22 -4,-2.1 4,-2.1 -5,-0.2 -2,-0.2 0.919 109.4 45.4 -66.2 -42.2 -50.7 106.8 126.4 222 383 A V H X S+ 0 0 0 -4,-2.3 4,-2.3 2,-0.2 -2,-0.2 0.932 114.4 48.2 -62.5 -44.5 -47.9 105.6 128.6 223 384 A L H X S+ 0 0 0 -4,-2.2 4,-2.3 2,-0.2 5,-0.2 0.899 110.3 51.4 -65.4 -41.1 -49.7 102.2 129.3 224 385 A R H X S+ 0 0 62 -4,-2.8 4,-2.0 1,-0.2 -1,-0.2 0.938 113.9 44.5 -57.4 -48.8 -50.4 101.7 125.6 225 386 A N H X S+ 0 0 0 -4,-2.1 4,-2.8 1,-0.2 -2,-0.2 0.851 109.5 57.3 -65.4 -33.5 -46.7 102.4 124.8 226 387 A M H X S+ 0 0 0 -4,-2.3 4,-2.4 2,-0.2 -1,-0.2 0.929 109.2 43.1 -63.6 -49.5 -45.6 100.1 127.7 227 388 A V H X S+ 0 0 0 -4,-2.3 4,-2.2 2,-0.2 -1,-0.2 0.892 114.1 51.6 -66.4 -37.1 -47.4 97.1 126.4 228 389 A H H X S+ 0 0 0 -4,-2.0 4,-1.9 -5,-0.2 -2,-0.2 0.924 109.6 50.6 -63.6 -41.8 -46.2 97.8 122.8 229 390 A C H < S+ 0 0 0 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.925 110.4 49.3 -60.3 -43.2 -42.6 98.1 124.2 230 391 A A H >< S+ 0 0 0 -4,-2.4 3,-1.4 1,-0.2 -1,-0.2 0.891 109.9 51.1 -63.5 -39.7 -43.0 94.7 125.9 231 392 A D H 3< S+ 0 0 21 -4,-2.2 3,-0.4 1,-0.3 -1,-0.2 0.879 115.5 42.8 -62.3 -36.4 -44.4 93.2 122.7 232 393 A L T 3< S+ 0 0 12 -4,-1.9 -1,-0.3 1,-0.2 -2,-0.2 -0.039 87.6 104.0 -99.1 30.2 -41.3 94.6 120.9 233 394 A S X + 0 0 0 -3,-1.4 3,-2.0 1,-0.2 4,-0.4 0.541 43.6 95.7 -94.4 -7.4 -38.9 93.6 123.6 234 395 A N G > S+ 0 0 13 -3,-0.4 3,-1.6 1,-0.3 -1,-0.2 0.884 85.0 50.7 -55.8 -43.3 -37.2 90.5 122.1 235 396 A P G 3 S+ 0 0 1 0, 0.0 -1,-0.3 0, 0.0 80,-0.2 0.584 104.0 61.2 -71.4 -8.9 -34.2 92.4 120.7 236 397 A T G < S+ 0 0 1 -3,-2.0 76,-0.2 -4,-0.1 -2,-0.2 0.393 89.4 91.4 -92.2 -0.7 -33.6 94.0 124.2 237 398 A K S < S- 0 0 5 -3,-1.6 5,-0.1 -4,-0.4 78,-0.1 -0.515 96.7 -70.9 -90.8 161.9 -33.1 90.7 125.9 238 399 A S >> - 0 0 71 -2,-0.2 4,-2.3 1,-0.1 3,-1.6 -0.207 53.4-111.5 -49.8 139.4 -29.8 88.9 126.4 239 400 A L H 3> S+ 0 0 38 1,-0.3 4,-2.9 2,-0.2 5,-0.2 0.802 114.8 58.3 -49.2 -40.6 -28.5 87.6 123.1 240 401 A E H 3> S+ 0 0 130 1,-0.2 4,-0.7 2,-0.2 -1,-0.3 0.828 114.3 39.8 -63.9 -28.8 -28.9 83.9 123.9 241 402 A L H <> S+ 0 0 11 -3,-1.6 4,-1.9 2,-0.2 3,-0.4 0.904 112.5 54.0 -83.5 -45.8 -32.6 84.6 124.5 242 403 A Y H X S+ 0 0 1 -4,-2.3 4,-2.5 1,-0.2 -2,-0.2 0.904 104.7 56.2 -53.6 -43.3 -33.1 87.0 121.6 243 404 A R H X S+ 0 0 128 -4,-2.9 4,-2.3 1,-0.2 -1,-0.2 0.866 105.2 51.6 -60.8 -37.1 -31.6 84.4 119.2 244 405 A Q H X S+ 0 0 69 -4,-0.7 4,-1.6 -3,-0.4 -1,-0.2 0.906 110.5 48.5 -65.2 -43.1 -34.3 81.9 120.2 245 406 A W H X S+ 0 0 4 -4,-1.9 4,-2.6 2,-0.2 5,-0.2 0.894 110.6 51.0 -60.5 -41.2 -37.0 84.5 119.6 246 407 A T H X S+ 0 0 2 -4,-2.5 4,-2.5 1,-0.2 5,-0.3 0.927 107.2 53.4 -65.1 -42.6 -35.5 85.3 116.1 247 408 A D H X S+ 0 0 113 -4,-2.3 4,-1.6 1,-0.2 -1,-0.2 0.895 112.4 46.2 -55.3 -41.4 -35.5 81.5 115.3 248 409 A R H X S+ 0 0 83 -4,-1.6 4,-2.0 2,-0.2 -2,-0.2 0.911 112.1 46.8 -73.3 -45.0 -39.2 81.4 116.1 249 410 A I H X S+ 0 0 23 -4,-2.6 4,-2.9 2,-0.2 5,-0.2 0.900 112.1 51.4 -66.6 -38.2 -40.4 84.5 114.3 250 411 A M H X S+ 0 0 6 -4,-2.5 4,-2.8 1,-0.2 5,-0.2 0.892 108.4 52.5 -68.3 -34.4 -38.5 83.5 111.1 251 412 A E H X S+ 0 0 91 -4,-1.6 4,-1.9 -5,-0.3 -1,-0.2 0.925 112.6 44.7 -61.5 -43.0 -40.1 80.1 111.3 252 413 A E H X S+ 0 0 8 -4,-2.0 4,-2.1 2,-0.2 -2,-0.2 0.910 114.7 48.9 -68.1 -39.9 -43.5 81.7 111.5 253 414 A F H X S+ 0 0 53 -4,-2.9 4,-2.9 2,-0.2 -2,-0.2 0.922 110.8 49.5 -62.2 -47.1 -42.6 84.3 108.7 254 415 A F H X S+ 0 0 37 -4,-2.8 4,-2.1 1,-0.2 19,-0.2 0.911 109.6 52.4 -64.6 -39.9 -41.3 81.6 106.3 255 416 A Q H X S+ 0 0 69 -4,-1.9 4,-1.6 -5,-0.2 -1,-0.2 0.912 110.4 46.9 -61.3 -45.6 -44.4 79.5 106.9 256 417 A Q H X S+ 0 0 9 -4,-2.1 4,-2.6 2,-0.2 -2,-0.2 0.933 110.6 53.7 -57.7 -45.4 -46.6 82.5 106.0 257 418 A G H X S+ 0 0 0 -4,-2.9 4,-2.5 1,-0.2 -2,-0.2 0.839 105.5 53.4 -59.1 -36.3 -44.4 83.2 102.9 258 419 A D H X S+ 0 0 41 -4,-2.1 4,-2.1 2,-0.2 -1,-0.2 0.862 108.6 49.4 -64.9 -38.9 -45.0 79.6 101.8 259 420 A K H X S+ 0 0 80 -4,-1.6 4,-1.7 2,-0.2 -2,-0.2 0.929 111.5 49.3 -66.0 -42.8 -48.8 80.1 102.0 260 421 A E H <>S+ 0 0 2 -4,-2.6 5,-3.1 1,-0.2 4,-0.4 0.926 111.7 48.6 -58.9 -47.9 -48.5 83.3 100.0 261 422 A R H ><5S+ 0 0 91 -4,-2.5 3,-1.1 1,-0.2 -1,-0.2 0.898 111.1 49.9 -59.7 -42.1 -46.4 81.5 97.3 262 423 A E H 3<5S+ 0 0 157 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.784 110.2 50.4 -73.2 -24.6 -48.9 78.6 97.2 263 424 A R T 3<5S- 0 0 146 -4,-1.7 -1,-0.3 -3,-0.2 -2,-0.2 0.441 117.5-114.0 -85.1 -1.7 -51.8 81.0 96.7 264 425 A G T < 5S+ 0 0 71 -3,-1.1 -3,-0.2 -4,-0.4 2,-0.2 0.722 70.7 142.2 72.7 23.2 -49.9 82.8 93.9 265 426 A M < - 0 0 45 -5,-3.1 2,-0.3 -6,-0.2 -1,-0.2 -0.489 63.9 -91.1 -90.4 160.3 -49.7 86.0 96.1 266 427 A E - 0 0 167 -2,-0.2 2,-0.3 -3,-0.1 -1,-0.1 -0.579 50.9-114.2 -64.5 131.4 -46.7 88.4 96.3 267 428 A I - 0 0 44 -2,-0.3 5,-0.1 1,-0.1 3,-0.1 -0.572 32.4-114.2 -75.9 135.1 -44.6 87.1 99.2 268 429 A S > - 0 0 22 -2,-0.3 3,-1.8 1,-0.2 4,-0.3 -0.160 44.7 -76.6 -68.9 159.6 -44.5 89.5 102.2 269 430 A P T 3 S+ 0 0 96 0, 0.0 -1,-0.2 0, 0.0 -12,-0.0 -0.360 118.2 7.3 -59.1 136.2 -41.2 91.2 103.2 270 431 A M T 3 S+ 0 0 80 -3,-0.1 -16,-0.1 2,-0.1 -13,-0.1 0.477 106.4 98.6 74.3 6.9 -38.8 88.8 105.1 271 432 A C < + 0 0 4 -3,-1.8 2,-0.9 -14,-0.1 -14,-0.2 0.479 49.2 95.8-107.3 -4.1 -41.1 85.8 104.4 272 433 A D >> - 0 0 43 -4,-0.3 4,-3.2 1,-0.2 3,-1.7 -0.785 55.0-166.6 -92.4 103.1 -39.3 84.2 101.3 273 434 A K T 34 S+ 0 0 96 -2,-0.9 -1,-0.2 1,-0.3 -19,-0.1 0.682 84.4 60.7 -65.0 -22.2 -37.0 81.5 102.8 274 435 A H T 34 S+ 0 0 143 1,-0.1 -1,-0.3 -3,-0.1 -2,-0.0 0.629 125.5 14.7 -78.5 -15.8 -35.1 81.1 99.5 275 436 A T T <4 S+ 0 0 112 -3,-1.7 -2,-0.2 2,-0.0 2,-0.1 0.546 94.9 113.2-131.4 -16.5 -34.0 84.8 99.7 276 437 A A < - 0 0 27 -4,-3.2 2,-0.6 1,-0.1 3,-0.1 -0.397 51.7-147.6 -72.4 133.7 -34.6 86.2 103.2 277 438 A S > - 0 0 19 1,-0.1 4,-2.1 -2,-0.1 5,-0.2 -0.923 2.1-159.5 -94.2 117.8 -31.6 87.2 105.4 278 439 A V H > S+ 0 0 33 -2,-0.6 4,-1.9 1,-0.2 -1,-0.1 0.912 93.0 48.1 -59.6 -40.2 -32.6 86.6 109.0 279 440 A E H > S+ 0 0 51 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.921 110.6 48.2 -73.3 -44.9 -29.8 89.0 110.2 280 441 A K H > S+ 0 0 128 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.894 110.3 54.3 -61.4 -40.3 -30.7 91.8 107.8 281 442 A S H X S+ 0 0 14 -4,-2.1 4,-2.3 1,-0.2 -1,-0.2 0.903 109.5 46.9 -59.7 -44.4 -34.4 91.5 108.8 282 443 A Q H X S+ 0 0 10 -4,-1.9 4,-2.6 2,-0.2 5,-0.2 0.916 111.7 49.6 -65.4 -43.8 -33.5 91.9 112.5 283 444 A V H X S+ 0 0 10 -4,-2.4 4,-3.0 1,-0.2 5,-0.2 0.933 113.5 46.5 -63.3 -44.4 -31.2 94.9 111.9 284 445 A G H X S+ 0 0 25 -4,-2.6 4,-2.9 2,-0.2 5,-0.3 0.916 111.3 52.5 -61.2 -43.5 -33.9 96.7 109.8 285 446 A F H X>S+ 0 0 59 -4,-2.3 4,-2.1 -5,-0.2 5,-2.0 0.927 114.3 42.6 -56.7 -48.4 -36.6 95.8 112.5 286 447 A I H <>S+ 0 0 1 -4,-2.6 5,-3.0 3,-0.2 -2,-0.2 0.937 116.4 46.8 -66.9 -48.0 -34.4 97.3 115.2 287 448 A D H <5S+ 0 0 60 -4,-3.0 -2,-0.2 -5,-0.2 -1,-0.2 0.916 123.0 31.7 -65.0 -41.3 -33.3 100.4 113.2 288 449 A Y H <5S+ 0 0 183 -4,-2.9 -1,-0.2 -5,-0.2 -2,-0.2 0.736 137.8 5.3 -90.3 -23.5 -36.8 101.3 111.9 289 450 A I T X5S+ 0 0 31 -4,-2.1 4,-1.6 -5,-0.3 -3,-0.2 0.694 122.8 43.3-125.3 -60.0 -39.1 100.2 114.8 290 451 A V H > S+ 0 0 31 0, 0.0 4,-1.5 0, 0.0 -1,-0.2 0.927 116.5 43.7 -56.5 -42.3 -36.8 104.5 118.0 293 454 A L H X S+ 0 0 0 -4,-1.6 4,-2.7 2,-0.2 -2,-0.2 0.960 117.1 42.8 -65.0 -54.8 -39.5 103.2 120.4 294 455 A W H X S+ 0 0 0 -4,-2.9 4,-2.9 1,-0.2 -3,-0.2 0.838 111.6 54.3 -68.9 -33.5 -37.1 102.0 123.1 295 456 A E H X S+ 0 0 85 -4,-2.9 4,-1.9 -5,-0.2 -1,-0.2 0.901 111.6 46.4 -62.1 -40.0 -34.8 105.1 122.9 296 457 A T H X S+ 0 0 6 -4,-1.5 4,-2.3 -5,-0.3 -2,-0.2 0.935 113.3 48.1 -70.5 -42.9 -37.9 107.3 123.5 297 458 A W H X S+ 0 0 1 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.937 109.9 53.6 -57.4 -46.4 -39.1 105.0 126.3 298 459 A A H < S+ 0 0 8 -4,-2.9 7,-0.3 1,-0.2 -1,-0.2 0.881 108.5 49.5 -56.8 -39.7 -35.6 105.2 127.8 299 460 A D H >< S+ 0 0 69 -4,-1.9 3,-0.9 1,-0.2 -1,-0.2 0.903 108.1 53.3 -67.2 -41.6 -35.8 109.0 127.7 300 461 A L H 3< S+ 0 0 5 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.904 122.4 29.3 -55.2 -45.1 -39.2 109.0 129.4 301 462 A V T >< S- 0 0 1 -4,-2.2 3,-2.3 -5,-0.1 -208,-0.3 0.117 100.1-160.6-107.1 22.2 -37.9 106.8 132.3 302 463 A Q T < + 0 0 114 -3,-0.9 -3,-0.1 1,-0.3 -4,-0.0 -0.141 65.2 9.5 -58.0 138.7 -34.3 107.9 132.4 303 464 A P T > S+ 0 0 86 0, 0.0 3,-1.7 0, 0.0 -1,-0.3 -0.918 111.4 79.5 -98.0 19.1 -32.0 106.4 133.6 304 465 A D T < S+ 0 0 61 -3,-2.3 3,-0.2 1,-0.3 4,-0.2 0.675 95.3 45.7 -67.8 -23.4 -34.0 103.2 134.4 305 466 A A T 3> S+ 0 0 3 -7,-0.3 4,-2.9 1,-0.2 -1,-0.3 0.217 78.5 111.5-100.1 12.6 -33.9 101.7 130.8 306 467 A Q H <> S+ 0 0 116 -3,-1.7 4,-2.4 1,-0.2 -1,-0.2 0.883 80.0 42.6 -56.0 -45.8 -30.2 102.3 130.3 307 468 A D H > S+ 0 0 117 -3,-0.2 4,-2.4 -4,-0.2 -1,-0.2 0.846 113.9 53.2 -72.6 -32.8 -29.1 98.6 130.4 308 469 A I H > S+ 0 0 25 2,-0.2 4,-2.3 -4,-0.2 -2,-0.2 0.938 112.1 44.1 -63.4 -48.7 -32.1 97.6 128.3 309 470 A L H X S+ 0 0 20 -4,-2.9 4,-2.2 2,-0.2 -2,-0.2 0.922 112.9 51.4 -65.5 -42.1 -31.2 100.2 125.6 310 471 A D H X S+ 0 0 70 -4,-2.4 4,-2.6 -5,-0.3 -1,-0.2 0.912 109.8 50.5 -59.3 -45.4 -27.5 99.3 125.7 311 472 A T H X S+ 0 0 41 -4,-2.4 4,-2.9 2,-0.2 5,-0.2 0.928 109.5 51.1 -58.1 -44.2 -28.4 95.6 125.2 312 473 A L H X S+ 0 0 0 -4,-2.3 4,-2.4 1,-0.2 -2,-0.2 0.925 112.5 45.6 -58.5 -45.0 -30.6 96.4 122.2 313 474 A E H X S+ 0 0 65 -4,-2.2 4,-2.2 2,-0.2 -1,-0.2 0.907 113.3 49.6 -69.4 -40.7 -27.8 98.4 120.6 314 475 A D H X S+ 0 0 107 -4,-2.6 4,-2.1 2,-0.2 -2,-0.2 0.927 112.3 47.6 -62.9 -44.2 -25.3 95.7 121.3 315 476 A N H X S+ 0 0 10 -4,-2.9 4,-2.9 -80,-0.2 5,-0.2 0.866 109.5 54.2 -65.0 -40.0 -27.6 93.0 119.9 316 477 A R H X S+ 0 0 55 -4,-2.4 4,-2.4 -5,-0.2 -1,-0.2 0.940 110.9 44.7 -57.3 -49.4 -28.3 95.1 116.8 317 478 A N H X S+ 0 0 79 -4,-2.2 4,-1.9 2,-0.2 -2,-0.2 0.844 111.9 53.1 -68.4 -34.0 -24.6 95.5 116.1 318 479 A W H X S+ 0 0 77 -4,-2.1 4,-1.0 2,-0.2 -2,-0.2 0.963 111.7 45.4 -63.4 -50.5 -24.0 91.8 116.7 319 480 A Y H >< S+ 0 0 9 -4,-2.9 3,-0.7 1,-0.2 4,-0.3 0.896 110.9 53.9 -59.7 -37.9 -26.7 90.8 114.2 320 481 A Q H >< S+ 0 0 85 -4,-2.4 3,-1.4 1,-0.2 -1,-0.2 0.907 104.8 54.0 -64.8 -37.5 -25.3 93.3 111.7 321 482 A S H 3< S+ 0 0 88 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.719 104.9 56.1 -67.4 -21.0 -21.9 91.7 112.0 322 483 A M T << S+ 0 0 92 -4,-1.0 -1,-0.3 -3,-0.7 -2,-0.2 0.387 77.3 125.9 -90.9 -0.3 -23.5 88.3 111.1 323 484 A I < 0 0 65 -3,-1.4 -3,-0.0 -4,-0.3 -46,-0.0 -0.371 360.0 360.0 -60.6 134.6 -25.1 89.6 107.8 324 485 A P 0 0 130 0, 0.0 -44,-0.1 0, 0.0 -1,-0.1 -0.724 360.0 360.0 -95.6 360.0 -24.1 87.4 104.8