==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 03-JAN-02 1KQ0 . COMPND 2 MOLECULE: METHIONINE AMINOPEPTIDASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR M.C.NONATO,J.WIDOM,J.CLARDY . 354 4 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15271.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 237 66.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 79 22.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 22 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 9.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 87 24.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 1 0 1 1 0 0 2 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 5 3 2 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 111 A V 0 0 129 0, 0.0 2,-0.0 0, 0.0 11,-0.0 0.000 360.0 360.0 360.0 118.4 38.1 14.6 -4.4 2 112 A Q - 0 0 52 1,-0.1 2,-0.2 5,-0.1 8,-0.0 -0.324 360.0-122.5 -54.6 143.6 38.1 17.0 -1.5 3 113 A T - 0 0 39 2,-0.1 5,-0.1 -2,-0.0 4,-0.1 -0.488 25.8-103.2 -82.8 157.9 41.3 18.5 -0.2 4 114 A D S S+ 0 0 103 1,-0.3 3,-0.0 -2,-0.2 -2,-0.0 -0.932 122.4 35.8-125.5 108.0 42.7 18.3 3.3 5 115 A P S S- 0 0 75 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.374 124.1-105.8 -77.0 154.5 42.1 20.8 4.5 6 116 A P + 0 0 27 0, 0.0 -2,-0.1 0, 0.0 78,-0.1 -0.045 60.4 140.8 -55.1 135.6 38.8 21.1 2.7 7 117 A S + 0 0 62 -4,-0.1 -5,-0.1 76,-0.1 -3,-0.1 0.393 40.7 98.7-148.1 -15.7 38.6 23.5 -0.2 8 118 A V S S- 0 0 35 -5,-0.1 5,-0.1 1,-0.1 -1,-0.1 -0.745 76.0-119.9 -86.5 118.1 36.5 21.8 -2.9 9 119 A P >> - 0 0 21 0, 0.0 3,-0.8 0, 0.0 4,-0.6 -0.180 16.8-122.7 -53.2 143.9 32.9 22.9 -2.9 10 120 A I H >> S+ 0 0 0 74,-2.5 3,-1.3 1,-0.2 4,-0.9 0.858 112.2 62.7 -57.3 -35.5 30.4 20.2 -2.3 11 121 A C H 34 S+ 0 0 33 73,-0.5 3,-0.5 1,-0.3 6,-0.3 0.873 102.6 49.9 -57.8 -36.2 28.7 21.1 -5.6 12 122 A D H <4 S+ 0 0 90 -3,-0.8 -1,-0.3 1,-0.2 -2,-0.2 0.554 104.5 58.4 -81.1 -10.6 32.0 20.1 -7.5 13 123 A L H << S+ 0 0 37 -3,-1.3 -1,-0.2 -4,-0.6 -2,-0.2 0.635 110.4 42.0 -91.0 -19.2 32.2 16.7 -5.7 14 124 A Y S >< S- 0 0 74 -4,-0.9 3,-2.0 -3,-0.5 -1,-0.2 -0.786 71.7-178.9-128.4 83.5 28.8 15.6 -7.0 15 125 A P T 3 S+ 0 0 112 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.757 76.7 60.6 -61.0 -30.3 28.7 16.7 -10.6 16 126 A N T 3 S- 0 0 150 2,-0.2 3,-0.1 1,-0.1 -5,-0.0 0.466 110.4-118.9 -77.3 -2.0 25.2 15.4 -11.4 17 127 A G S < S+ 0 0 30 -3,-2.0 2,-0.6 -6,-0.3 31,-0.1 0.689 74.5 128.5 72.9 17.5 23.9 17.7 -8.7 18 128 A V - 0 0 100 -7,-0.1 -1,-0.2 -4,-0.1 -2,-0.2 -0.936 43.0-160.2-107.9 121.6 22.5 14.7 -6.7 19 129 A F - 0 0 11 -2,-0.6 29,-0.1 -3,-0.1 28,-0.1 -0.729 25.7 -86.7-109.0 152.7 23.6 14.8 -3.1 20 130 A P - 0 0 42 0, 0.0 31,-0.1 0, 0.0 30,-0.1 -0.196 40.5-119.9 -58.3 138.1 23.8 12.0 -0.4 21 131 A K - 0 0 106 1,-0.1 3,-0.1 329,-0.0 2,-0.1 -0.360 22.5-130.4 -70.8 152.9 20.8 11.1 1.6 22 132 A G - 0 0 12 1,-0.2 2,-0.4 -2,-0.1 327,-0.3 -0.123 58.1 -49.7 -83.0-164.0 21.0 11.5 5.4 23 133 A Q E -A 348 0A 81 325,-1.6 325,-3.1 -2,-0.1 2,-0.5 -0.583 60.5-150.6 -72.9 125.6 19.9 8.6 7.6 24 134 A E E -A 347 0A 88 -2,-0.4 2,-0.3 323,-0.2 323,-0.2 -0.869 17.8-179.8-102.3 132.1 16.4 7.4 6.5 25 135 A C E -A 346 0A 37 321,-2.8 321,-2.8 -2,-0.5 2,-0.2 -0.955 30.0-115.2-130.9 146.8 14.1 5.9 9.1 26 136 A E - 0 0 65 -2,-0.3 319,-0.1 319,-0.2 318,-0.0 -0.506 47.4 -97.9 -74.2 149.4 10.6 4.5 9.0 27 137 A Y 0 0 63 317,-0.2 142,-0.1 -2,-0.2 -1,-0.1 -0.383 360.0 360.0 -68.6 145.5 8.2 6.5 11.1 28 138 A P 0 0 116 0, 0.0 -1,-0.1 0, 0.0 142,-0.0 -0.329 360.0 360.0 -56.7 360.0 7.4 5.2 14.6 29 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 30 153 A E > 0 0 197 0, 0.0 4,-1.4 0, 0.0 5,-0.1 0.000 360.0 360.0 360.0-132.3 2.0 5.0 -4.0 31 154 A E H > + 0 0 133 2,-0.2 4,-2.5 1,-0.2 5,-0.1 0.832 360.0 52.9 -70.5 -35.6 0.6 8.5 -3.8 32 155 A K H > S+ 0 0 88 2,-0.2 4,-2.5 1,-0.2 312,-0.2 0.863 106.8 52.1 -71.1 -34.3 3.0 9.4 -1.0 33 156 A K H > S+ 0 0 142 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.871 111.1 47.9 -68.1 -36.2 5.9 8.2 -2.9 34 157 A A H X S+ 0 0 59 -4,-1.4 4,-1.6 2,-0.2 -2,-0.2 0.923 112.1 49.6 -67.1 -44.6 4.8 10.4 -5.8 35 158 A L H < S+ 0 0 78 -4,-2.5 4,-0.5 1,-0.2 -2,-0.2 0.855 110.1 51.4 -62.4 -38.8 4.4 13.3 -3.3 36 159 A D H >< S+ 0 0 4 -4,-2.5 3,-1.2 1,-0.2 -1,-0.2 0.936 109.3 49.2 -63.1 -49.3 7.9 12.6 -1.9 37 160 A Q H >< S+ 0 0 125 -4,-2.1 3,-1.6 1,-0.3 4,-0.2 0.780 99.1 67.5 -63.6 -30.2 9.5 12.7 -5.4 38 161 A A T 3< S+ 0 0 85 -4,-1.6 -1,-0.3 1,-0.3 3,-0.2 0.736 105.2 42.4 -63.3 -23.2 7.8 15.9 -6.4 39 162 A S T X> S+ 0 0 39 -3,-1.2 4,-1.9 -4,-0.5 3,-0.8 0.146 77.5 118.2-109.8 17.9 9.9 17.8 -3.7 40 163 A E H <> S+ 0 0 48 -3,-1.6 4,-2.6 1,-0.3 5,-0.2 0.837 71.0 58.0 -52.6 -39.4 13.1 16.0 -4.6 41 164 A E H 3> S+ 0 0 170 -3,-0.2 4,-1.5 -4,-0.2 -1,-0.3 0.870 107.6 48.9 -62.9 -34.8 14.8 19.3 -5.6 42 165 A I H <> S+ 0 0 45 -3,-0.8 4,-2.0 2,-0.2 -2,-0.2 0.948 111.7 46.1 -68.3 -49.1 14.1 20.6 -2.1 43 166 A W H X S+ 0 0 12 -4,-1.9 4,-2.4 1,-0.2 -2,-0.2 0.891 110.7 55.8 -61.1 -38.3 15.5 17.5 -0.3 44 167 A N H X S+ 0 0 28 -4,-2.6 4,-2.1 -5,-0.2 -1,-0.2 0.867 104.6 51.3 -61.4 -40.7 18.5 17.7 -2.5 45 168 A D H X S+ 0 0 37 -4,-1.5 4,-2.2 -3,-0.2 -1,-0.2 0.917 110.6 48.9 -62.6 -45.0 19.2 21.3 -1.5 46 169 A F H X S+ 0 0 8 -4,-2.0 4,-2.2 1,-0.2 -2,-0.2 0.909 111.3 50.8 -58.4 -42.9 19.0 20.3 2.2 47 170 A R H X S+ 0 0 3 -4,-2.4 4,-2.2 2,-0.2 -1,-0.2 0.848 107.4 51.8 -67.0 -37.9 21.4 17.3 1.4 48 171 A E H X S+ 0 0 20 -4,-2.1 4,-1.8 1,-0.2 -1,-0.2 0.950 112.7 46.3 -63.4 -47.5 23.9 19.5 -0.3 49 172 A A H X S+ 0 0 0 -4,-2.2 4,-2.1 1,-0.2 -2,-0.2 0.844 111.3 53.1 -62.2 -35.4 23.9 21.9 2.7 50 173 A A H X S+ 0 0 0 -4,-2.2 4,-2.8 2,-0.2 -1,-0.2 0.884 105.5 52.0 -69.3 -41.0 24.2 18.9 5.0 51 174 A E H X S+ 0 0 25 -4,-2.2 4,-2.5 2,-0.2 5,-0.2 0.903 109.0 51.4 -62.7 -39.8 27.2 17.5 3.3 52 175 A A H X S+ 0 0 1 -4,-1.8 4,-3.0 2,-0.2 5,-0.2 0.957 110.6 49.2 -60.3 -47.5 28.9 20.9 3.6 53 176 A H H X S+ 0 0 0 -4,-2.1 4,-2.5 1,-0.2 5,-0.2 0.900 110.4 50.6 -56.8 -45.3 28.0 20.8 7.3 54 177 A R H X S+ 0 0 30 -4,-2.8 4,-2.1 2,-0.2 -1,-0.2 0.925 113.9 43.7 -59.9 -46.2 29.5 17.3 7.7 55 178 A Q H X S+ 0 0 30 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.921 114.0 49.7 -70.3 -42.3 32.7 18.2 6.0 56 179 A V H X S+ 0 0 7 -4,-3.0 4,-2.8 -5,-0.2 -2,-0.2 0.961 113.3 46.0 -57.8 -52.9 33.1 21.5 7.8 57 180 A R H X S+ 0 0 0 -4,-2.5 4,-2.7 1,-0.2 -2,-0.2 0.882 109.5 53.7 -62.5 -40.3 32.5 20.0 11.3 58 181 A K H X S+ 0 0 122 -4,-2.1 4,-1.0 -5,-0.2 -1,-0.2 0.923 111.8 47.4 -56.6 -43.3 34.9 17.0 10.6 59 182 A Y H >X S+ 0 0 36 -4,-2.0 3,-1.0 1,-0.2 4,-0.9 0.955 110.9 50.1 -62.7 -51.8 37.6 19.6 9.8 60 183 A V H >X S+ 0 0 0 -4,-2.8 4,-2.6 1,-0.3 3,-0.9 0.900 106.0 56.2 -54.6 -45.1 36.8 21.7 12.9 61 184 A M H 3< S+ 0 0 72 -4,-2.7 -1,-0.3 1,-0.2 -2,-0.2 0.793 102.3 58.8 -60.3 -26.8 37.1 18.6 15.1 62 185 A S H << S+ 0 0 80 -4,-1.0 -1,-0.2 -3,-1.0 -2,-0.2 0.800 121.8 18.5 -73.3 -29.2 40.6 18.0 13.7 63 186 A W H << S+ 0 0 33 -4,-0.9 -2,-0.2 -3,-0.9 2,-0.2 0.580 84.2 117.8-121.5 -12.4 42.1 21.3 14.8 64 187 A I < + 0 0 6 -4,-2.6 -4,-0.0 -5,-0.2 9,-0.0 -0.417 42.7 156.8 -64.9 128.1 39.9 22.9 17.5 65 188 A K > - 0 0 106 -2,-0.2 3,-1.7 54,-0.0 54,-0.2 -0.996 49.2 -92.7-152.8 151.6 42.1 23.2 20.6 66 189 A P T 3 S+ 0 0 46 0, 0.0 54,-0.2 0, 0.0 3,-0.1 -0.375 108.5 51.6 -61.8 145.8 42.5 25.1 23.9 67 190 A G T 3 S+ 0 0 56 52,-2.5 2,-0.2 1,-0.5 53,-0.1 -0.094 85.3 107.3 111.9 -34.3 44.8 28.0 23.3 68 191 A M S < S- 0 0 37 -3,-1.7 51,-3.0 51,-0.1 -1,-0.5 -0.480 73.2-117.7 -77.1 147.3 42.9 29.3 20.2 69 192 A T B > -K 118 0B 32 49,-0.2 4,-2.1 -2,-0.2 49,-0.2 -0.502 21.6-119.3 -79.4 156.2 40.9 32.5 20.5 70 193 A M H > S+ 0 0 1 47,-2.3 4,-2.5 1,-0.2 5,-0.2 0.874 116.7 55.5 -62.6 -35.7 37.2 32.2 19.9 71 194 A I H > S+ 0 0 30 46,-0.4 4,-2.7 44,-0.3 5,-0.2 0.935 106.4 49.1 -60.6 -47.3 37.6 34.6 17.0 72 195 A E H > S+ 0 0 98 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.904 111.7 50.4 -59.4 -42.7 40.2 32.3 15.4 73 196 A I H X S+ 0 0 0 -4,-2.1 4,-2.4 1,-0.2 -1,-0.2 0.953 114.0 42.9 -60.4 -51.5 38.0 29.3 15.8 74 197 A C H X S+ 0 0 0 -4,-2.5 4,-2.9 1,-0.2 5,-0.2 0.876 114.6 49.6 -66.7 -38.8 34.9 31.0 14.2 75 198 A E H X S+ 0 0 98 -4,-2.7 4,-2.3 2,-0.2 -1,-0.2 0.918 112.9 46.8 -68.1 -41.2 36.9 32.6 11.4 76 199 A K H X S+ 0 0 86 -4,-2.3 4,-1.6 -5,-0.2 -2,-0.2 0.910 115.9 45.6 -65.7 -43.5 38.6 29.3 10.5 77 200 A L H < S+ 0 0 6 -4,-2.4 -2,-0.2 -5,-0.2 -1,-0.2 0.944 114.5 47.6 -62.0 -48.6 35.3 27.4 10.6 78 201 A E H < S+ 0 0 4 -4,-2.9 -2,-0.2 1,-0.2 5,-0.2 0.851 107.4 56.3 -65.9 -36.0 33.4 30.1 8.6 79 202 A D H < 0 0 80 -4,-2.3 4,-1.7 -5,-0.2 -1,-0.2 0.927 360.0 360.0 -58.8 -46.2 36.1 30.3 6.0 80 203 A C < 0 0 9 -4,-1.6 4,-2.6 2,-0.2 5,-0.3 0.912 360.0 360.0 -67.0 360.0 35.8 26.6 5.3 81 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 82 205 A R > 0 0 30 0, 0.0 5,-2.6 0, 0.0 4,-0.4 0.000 360.0 360.0 360.0 -41.0 31.9 29.6 2.8 83 206 A K T > 5 + 0 0 111 -4,-1.7 3,-0.6 3,-0.2 -3,-0.1 0.938 360.0 42.5 -66.0 -50.3 34.2 27.5 0.5 84 207 A L T 3 5S+ 0 0 0 -4,-2.6 -74,-2.5 1,-0.2 -73,-0.5 0.863 116.3 47.0 -70.9 -35.8 32.3 24.2 0.7 85 208 A I T 3 5S- 0 0 4 -5,-0.3 -1,-0.2 -76,-0.2 -2,-0.2 0.564 107.8-129.1 -79.5 -8.2 28.8 25.7 0.4 86 209 A K T < 5 - 0 0 104 -3,-0.6 -3,-0.2 -4,-0.4 -2,-0.1 0.983 27.8-128.8 56.1 63.0 30.1 27.8 -2.5 87 210 A E < + 0 0 84 -5,-2.6 6,-0.2 1,-0.1 2,-0.2 -0.067 38.7 169.2 -46.8 131.8 28.8 31.0 -1.0 88 211 A N B >> -B 92 0A 99 4,-3.1 3,-2.3 1,-0.5 4,-1.0 -0.662 52.1 -86.5-150.5 86.2 26.7 32.9 -3.5 89 212 A G T 34 S- 0 0 51 1,-0.3 -1,-0.5 -2,-0.2 3,-0.4 -0.175 100.6 -22.5 47.7-130.6 24.8 35.8 -2.1 90 213 A L T 34 S+ 0 0 56 1,-0.2 -1,-0.3 195,-0.1 45,-0.2 0.434 131.5 72.6 -88.0 -0.9 21.4 34.6 -0.8 91 214 A N T <4 S+ 0 0 93 -3,-2.3 43,-3.2 1,-0.3 2,-0.3 0.741 114.0 6.7 -86.5 -23.7 21.4 31.5 -3.0 92 215 A A E < S+BC 88 133A 9 -4,-1.0 -4,-3.1 -3,-0.4 -1,-0.3 -0.934 91.8 87.6-156.5 133.1 24.1 29.7 -1.0 93 216 A G E S- C 0 132A 2 39,-1.7 39,-1.9 -2,-0.3 2,-0.5 -0.974 71.2 -27.0 174.6-159.8 25.7 30.6 2.2 94 217 A L E - C 0 131A 26 -2,-0.3 37,-0.3 37,-0.2 -2,-0.1 -0.785 42.3-156.3 -87.5 126.9 26.0 30.6 6.0 95 218 A A E S- 0 0 2 35,-1.2 196,-0.9 -2,-0.5 36,-0.2 0.788 71.2 -15.9 -76.5 -29.3 22.5 30.3 7.5 96 219 A F E S- C 0 130A 3 34,-0.6 34,-0.9 194,-0.1 -1,-0.2 -0.968 87.2 -69.6-168.0 162.3 23.4 31.9 10.9 97 220 A P E - 0 0 0 0, 0.0 2,-0.9 0, 0.0 11,-0.1 -0.167 56.0 -91.8 -63.9 158.6 26.5 32.8 12.9 98 221 A T E - 0 0 2 31,-0.1 2,-0.3 -24,-0.1 31,-0.2 -0.597 37.1-150.2 -73.8 104.1 28.8 30.2 14.5 99 222 A G E + C 0 128A 4 29,-3.1 29,-1.5 -2,-0.9 11,-0.2 -0.566 26.0 166.3 -67.9 134.8 27.7 29.6 18.0 100 223 A C E + C 0 127A 0 9,-2.7 27,-0.2 -2,-0.3 10,-0.1 -0.109 17.2 178.2-141.5 37.5 30.6 28.7 20.2 101 224 A S E - C 0 126A 2 25,-0.7 25,-2.6 8,-0.3 2,-0.4 -0.130 16.5-142.2 -51.0 129.4 28.9 29.2 23.6 102 225 A L E > - C 0 125A 23 23,-0.2 3,-2.4 5,-0.1 23,-0.2 -0.792 41.9 -46.7-105.5 135.0 31.1 28.4 26.6 103 226 A N T 3 S+ 0 0 38 21,-2.0 229,-1.9 -2,-0.4 223,-0.1 -0.244 129.8 12.4 61.5-113.3 30.4 26.7 29.9 104 227 A N T 3 S+ 0 0 33 227,-0.2 222,-2.9 -2,-0.2 2,-0.5 0.683 114.5 88.7 -72.2 -16.8 27.2 28.0 31.6 105 228 A a E < +L 325 0C 7 -3,-2.4 220,-0.3 220,-0.3 21,-0.2 -0.724 54.2 177.4 -88.7 125.0 26.4 29.7 28.4 106 229 A A E + 0 0 1 218,-2.2 2,-0.3 -2,-0.5 -5,-0.2 0.784 54.7 3.4 -97.3 -33.9 24.4 27.4 26.1 107 230 A A E S+L 324 0C 6 217,-1.3 217,-2.2 -5,-0.1 -1,-0.2 -0.972 99.6 36.1-155.5 161.5 23.5 29.3 23.0 108 231 A H S S+ 0 0 19 -2,-0.3 2,-0.6 215,-0.2 150,-0.4 0.591 70.8 128.4 66.6 18.0 23.9 32.6 20.9 109 232 A Y + 0 0 19 213,-0.1 -9,-2.7 215,-0.1 -8,-0.3 -0.917 16.1 147.7-104.4 125.5 27.4 33.5 21.8 110 233 A T - 0 0 1 -2,-0.6 -11,-0.1 -11,-0.2 -39,-0.1 -0.950 52.2 -98.8-142.7 143.6 29.8 34.2 19.0 111 234 A P - 0 0 0 0, 0.0 184,-0.3 0, 0.0 2,-0.2 -0.344 28.8-147.3 -66.3 144.7 32.6 36.8 19.6 112 235 A N > - 0 0 8 1,-0.2 3,-1.9 182,-0.1 -41,-0.1 -0.549 49.1 -61.4 -93.6 171.0 32.3 40.4 18.4 113 236 A A T 3 S+ 0 0 68 1,-0.2 -1,-0.2 -2,-0.2 3,-0.1 -0.222 125.9 24.1 -50.6 140.2 35.4 42.3 17.2 114 237 A G T 3 S+ 0 0 70 1,-0.3 2,-0.4 -3,-0.1 -1,-0.2 0.305 79.8 144.6 84.7 -10.4 38.0 42.7 20.0 115 238 A D < - 0 0 40 -3,-1.9 -44,-0.3 1,-0.2 -1,-0.3 -0.500 27.1-173.8 -64.6 118.0 36.8 39.7 22.0 116 239 A T + 0 0 118 -2,-0.4 -1,-0.2 -3,-0.1 -3,-0.0 0.314 29.5 143.0 -97.5 7.7 40.0 38.2 23.5 117 240 A T - 0 0 53 -48,-0.1 -47,-2.3 1,-0.1 2,-0.4 -0.264 36.2-153.8 -53.8 133.2 38.4 35.1 25.0 118 241 A V B -K 69 0B 53 -49,-0.2 2,-0.3 -48,-0.1 -49,-0.2 -0.876 19.7-113.4-113.4 137.9 40.7 32.0 24.7 119 242 A L - 0 0 0 -51,-3.0 -52,-2.5 -2,-0.4 2,-0.2 -0.550 38.3-151.4 -73.0 129.7 39.4 28.5 24.6 120 243 A Q > - 0 0 100 -2,-0.3 3,-1.7 -54,-0.2 26,-0.1 -0.688 24.4-116.1-107.3 158.9 40.5 26.6 27.8 121 244 A Y T 3 S+ 0 0 116 1,-0.3 25,-0.6 -2,-0.2 26,-0.4 0.837 118.0 45.4 -58.3 -38.1 41.2 22.9 28.5 122 245 A D T 3 S+ 0 0 73 24,-0.1 -1,-0.3 23,-0.1 2,-0.1 0.317 89.6 118.6 -89.4 6.5 38.2 22.8 30.9 123 246 A D < - 0 0 16 -3,-1.7 2,-0.6 -21,-0.1 23,-0.4 -0.447 53.5-151.6 -75.0 147.1 35.8 24.6 28.6 124 247 A I - 0 0 0 21,-0.1 -21,-2.0 -2,-0.1 2,-0.5 -0.970 23.8-168.7-118.2 105.6 32.6 23.0 27.3 125 248 A C E -CD 102 144A 0 19,-2.4 19,-3.5 -2,-0.6 2,-0.8 -0.876 15.9-149.6-106.5 125.9 32.0 24.6 23.9 126 249 A K E -CD 101 143A 1 -25,-2.6 2,-0.8 -2,-0.5 -25,-0.7 -0.845 10.3-162.9 -98.9 109.4 28.8 24.3 21.9 127 250 A I E +CD 100 142A 0 15,-2.3 15,-2.3 -2,-0.8 2,-0.5 -0.838 19.3 165.0 -94.7 111.8 29.6 24.6 18.2 128 251 A D E +CD 99 141A 10 -29,-1.5 -29,-3.1 -2,-0.8 2,-0.3 -0.975 8.0 153.2-132.9 110.5 26.3 25.3 16.4 129 252 A F E - D 0 140A 7 11,-1.4 11,-1.2 -2,-0.5 2,-0.3 -0.947 24.7-145.0-140.6 159.6 26.5 26.6 12.8 130 253 A G E -CD 96 139A 1 -34,-0.9 -35,-1.2 -2,-0.3 -34,-0.6 -0.948 9.0-171.3-132.8 150.4 24.3 26.5 9.8 131 254 A T E -CD 94 138A 4 7,-1.2 7,-3.0 -2,-0.3 2,-0.3 -0.878 12.5-170.0-127.9 158.7 24.6 26.2 6.0 132 255 A H E -CD 93 137A 3 -39,-1.9 -39,-1.7 -2,-0.3 2,-0.4 -0.992 21.3-157.8-148.3 157.0 21.9 26.7 3.3 133 256 A I E > S-CD 92 136A 11 3,-1.3 3,-2.7 -2,-0.3 -41,-0.2 -0.991 91.2 -16.7-128.4 122.9 21.2 26.2 -0.3 134 257 A S T 3 S- 0 0 34 -43,-3.2 -43,-0.1 -2,-0.4 -42,-0.1 0.809 128.6 -54.0 51.9 35.1 18.3 28.4 -1.6 135 258 A G T 3 S+ 0 0 1 1,-0.3 78,-2.0 -45,-0.2 2,-0.9 0.578 102.8 134.0 79.5 5.8 17.2 29.0 2.0 136 259 A R E < -D 133 0A 50 -3,-2.7 -3,-1.3 76,-0.2 2,-0.3 -0.834 49.0-151.9 -88.4 107.0 17.0 25.3 2.7 137 260 A I E -D 132 0A 0 -2,-0.9 2,-0.6 74,-0.3 -5,-0.2 -0.662 22.8-158.3 -97.8 135.5 18.7 25.4 6.1 138 261 A I E -D 131 0A 0 -7,-3.0 -7,-1.2 -2,-0.3 2,-0.6 -0.951 11.8-176.0-104.7 118.1 20.8 22.9 8.0 139 262 A D E +D 130 0A 0 -2,-0.6 2,-0.3 -9,-0.2 101,-0.2 -0.976 22.2 151.1-113.7 108.3 20.8 23.7 11.7 140 263 A C E +D 129 0A 0 -11,-1.2 -11,-1.4 -2,-0.6 2,-0.3 -0.996 16.0 176.8-146.5 141.5 23.2 21.1 13.4 141 264 A A E -DE 128 336A 0 195,-1.6 195,-2.3 -2,-0.3 2,-0.3 -0.989 10.6-176.7-152.8 153.1 25.4 21.3 16.4 142 265 A F E -D 127 0A 6 -15,-2.3 -15,-2.3 -2,-0.3 2,-0.4 -0.913 27.0-112.4-144.1 168.6 27.7 19.4 18.7 143 266 A T E -D 126 0A 12 -2,-0.3 2,-0.5 -17,-0.2 -17,-0.2 -0.898 21.7-153.8-111.1 137.7 29.7 20.0 21.9 144 267 A V E +D 125 0A 11 -19,-3.5 -19,-2.4 -2,-0.4 2,-0.3 -0.925 22.0 159.5-112.8 127.6 33.5 20.1 22.2 145 268 A T - 0 0 29 -2,-0.5 -21,-0.1 -21,-0.2 -23,-0.1 -0.910 27.8-168.1-135.0 168.9 35.4 19.2 25.3 146 269 A F S S+ 0 0 50 -25,-0.6 -24,-0.1 -23,-0.4 -25,-0.1 0.487 73.5 75.8-128.5 -17.3 39.0 18.2 26.1 147 270 A N S > S- 0 0 28 -26,-0.4 3,-1.5 -24,-0.3 -1,-0.1 -0.886 73.1-143.7 -98.9 121.0 38.6 17.1 29.7 148 271 A P G > S+ 0 0 78 0, 0.0 3,-2.2 0, 0.0 4,-0.3 0.594 85.0 90.4 -60.1 -10.5 36.9 13.7 30.0 149 272 A K G 3 S+ 0 0 42 1,-0.3 3,-0.3 2,-0.1 4,-0.2 0.744 86.8 50.9 -58.8 -23.3 35.1 14.8 33.2 150 273 A Y G <> S+ 0 0 1 -3,-1.5 4,-2.5 1,-0.2 -1,-0.3 0.399 78.3 107.3 -92.7 4.4 32.2 15.9 30.9 151 274 A D H <> S+ 0 0 92 -3,-2.2 4,-2.3 1,-0.2 -1,-0.2 0.888 81.4 42.6 -52.0 -47.2 31.9 12.6 29.1 152 275 A T H > S+ 0 0 66 -4,-0.3 4,-2.5 -3,-0.3 -1,-0.2 0.854 111.1 54.9 -71.5 -34.0 28.7 11.5 30.7 153 276 A L H > S+ 0 0 1 -3,-0.2 4,-1.8 -4,-0.2 -1,-0.2 0.932 111.1 46.9 -62.3 -43.7 27.1 14.9 30.4 154 277 A L H X S+ 0 0 21 -4,-2.5 4,-2.3 1,-0.2 -2,-0.2 0.908 111.1 50.8 -62.8 -44.0 27.8 14.8 26.7 155 278 A K H X S+ 0 0 117 -4,-2.3 4,-2.6 -5,-0.2 5,-0.2 0.891 107.3 54.9 -63.7 -36.8 26.5 11.3 26.4 156 279 A A H X S+ 0 0 0 -4,-2.5 4,-2.4 1,-0.2 -1,-0.2 0.937 111.4 42.5 -61.9 -46.4 23.2 12.3 28.2 157 280 A V H X S+ 0 0 0 -4,-1.8 4,-2.7 2,-0.2 -1,-0.2 0.892 113.5 52.0 -70.6 -38.3 22.5 15.1 25.8 158 281 A K H X S+ 0 0 82 -4,-2.3 4,-2.8 2,-0.2 -1,-0.2 0.937 112.4 45.9 -61.7 -47.2 23.4 13.1 22.7 159 282 A D H X S+ 0 0 53 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.889 112.3 51.9 -60.2 -42.1 21.1 10.3 23.9 160 283 A A H X S+ 0 0 0 -4,-2.4 4,-2.2 -5,-0.2 -2,-0.2 0.912 111.6 46.4 -63.0 -42.0 18.4 12.9 24.6 161 284 A T H X S+ 0 0 2 -4,-2.7 4,-2.5 2,-0.2 -2,-0.2 0.934 112.1 49.5 -68.0 -44.6 18.7 14.3 21.1 162 285 A N H X S+ 0 0 38 -4,-2.8 4,-2.6 1,-0.2 -2,-0.2 0.873 110.0 52.6 -62.1 -35.1 18.7 10.9 19.5 163 286 A T H X S+ 0 0 20 -4,-2.4 4,-2.5 2,-0.2 -1,-0.2 0.924 109.1 49.1 -63.6 -46.0 15.6 10.1 21.5 164 287 A G H X S+ 0 0 0 -4,-2.2 4,-1.6 1,-0.2 -2,-0.2 0.913 112.2 48.8 -59.2 -43.5 13.9 13.2 20.3 165 288 A I H < S+ 0 0 2 -4,-2.5 -2,-0.2 2,-0.2 -1,-0.2 0.909 111.8 48.3 -63.2 -43.5 14.9 12.3 16.8 166 289 A K H < S+ 0 0 136 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.897 113.2 48.4 -64.3 -39.9 13.5 8.7 17.1 167 290 A C H < S+ 0 0 36 -4,-2.5 -1,-0.2 -5,-0.1 -2,-0.2 0.754 90.2 101.8 -72.1 -27.4 10.2 10.0 18.6 168 291 A A < + 0 0 0 -4,-1.6 2,-0.3 -5,-0.2 5,-0.1 -0.211 46.5 127.6 -62.6 148.6 9.6 12.6 15.9 169 292 A G > - 0 0 1 3,-0.1 3,-1.7 -142,-0.1 63,-0.4 -0.949 62.2 -62.4 175.9 167.3 7.2 11.8 13.2 170 293 A I T 3 S+ 0 0 42 -2,-0.3 63,-0.2 1,-0.3 3,-0.1 -0.514 123.2 12.8 -64.7 130.3 4.1 12.8 11.2 171 294 A D T 3 S+ 0 0 110 61,-3.0 2,-0.3 1,-0.3 -1,-0.3 0.455 94.4 136.8 78.5 3.0 1.1 13.0 13.5 172 295 A V < - 0 0 24 -3,-1.7 60,-2.3 60,-0.2 2,-0.3 -0.651 58.2-119.7 -81.0 134.7 3.4 12.9 16.6 173 296 A R B >> -N 231 0D 98 -2,-0.3 4,-1.4 58,-0.2 3,-0.8 -0.609 10.7-137.2 -75.9 132.8 2.5 15.4 19.4 174 297 A L H 3> S+ 0 0 3 56,-3.2 4,-1.9 -2,-0.3 3,-0.2 0.880 103.5 58.1 -57.2 -38.4 5.2 17.9 20.2 175 298 A C H 3> S+ 0 0 16 53,-1.5 4,-2.1 55,-0.3 -1,-0.2 0.823 102.5 54.6 -63.5 -30.9 4.6 17.5 23.9 176 299 A D H <> S+ 0 0 54 -3,-0.8 4,-2.7 2,-0.2 -1,-0.2 0.894 105.3 52.0 -68.0 -40.1 5.3 13.8 23.7 177 300 A V H X S+ 0 0 0 -4,-1.4 4,-2.7 -3,-0.2 -2,-0.2 0.931 111.1 48.1 -61.8 -46.1 8.7 14.4 22.1 178 301 A G H X S+ 0 0 0 -4,-1.9 4,-2.5 2,-0.2 47,-0.3 0.907 111.9 48.3 -60.5 -45.9 9.6 16.8 24.9 179 302 A E H X S+ 0 0 96 -4,-2.1 4,-2.5 45,-0.3 46,-0.2 0.930 112.8 49.7 -59.8 -46.0 8.4 14.4 27.6 180 303 A A H X S+ 0 0 21 -4,-2.7 4,-1.8 1,-0.2 -2,-0.2 0.915 111.2 48.4 -57.8 -46.5 10.4 11.6 25.9 181 304 A I H X S+ 0 0 0 -4,-2.7 4,-2.6 1,-0.2 -1,-0.2 0.908 111.7 50.3 -62.2 -42.8 13.5 13.8 25.7 182 305 A Q H X S+ 0 0 25 -4,-2.5 4,-2.9 1,-0.2 5,-0.2 0.928 105.9 55.0 -63.8 -46.4 13.2 14.7 29.3 183 306 A E H X S+ 0 0 150 -4,-2.5 4,-0.5 1,-0.2 -1,-0.2 0.915 113.8 40.5 -55.1 -48.0 12.9 11.1 30.5 184 307 A V H >< S+ 0 0 28 -4,-1.8 3,-1.3 2,-0.2 4,-0.3 0.955 114.8 51.9 -66.1 -47.4 16.1 10.0 28.8 185 308 A M H >< S+ 0 0 0 -4,-2.6 3,-1.3 1,-0.3 14,-0.3 0.905 110.8 46.7 -57.3 -46.5 18.0 13.2 29.8 186 309 A E H 3< S+ 0 0 58 -4,-2.9 -1,-0.3 1,-0.3 -2,-0.2 0.535 93.8 77.2 -77.1 -6.7 17.1 12.9 33.5 187 310 A S T << S+ 0 0 86 -3,-1.3 2,-0.4 -4,-0.5 -1,-0.3 0.619 85.3 85.1 -75.3 -9.4 18.0 9.2 33.5 188 311 A Y < - 0 0 25 -3,-1.3 11,-2.1 -4,-0.3 2,-0.4 -0.750 56.2-173.8 -99.7 137.5 21.7 10.4 33.6 189 312 A E E -O 198 0E 157 -2,-0.4 2,-0.3 9,-0.2 9,-0.2 -0.963 10.7-169.9-123.7 143.2 23.7 11.4 36.6 190 313 A V E -O 197 0E 10 7,-2.6 7,-2.5 -2,-0.4 2,-0.4 -0.910 17.1-146.2-131.9 159.6 27.2 12.8 36.3 191 314 A E E +O 196 0E 127 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -0.993 21.2 173.0-127.9 121.9 30.1 13.7 38.6 192 315 A I E > S-O 195 0E 3 3,-2.6 3,-1.7 -2,-0.4 -42,-0.0 -0.994 70.5 -14.1-133.1 121.9 32.2 16.7 37.8 193 316 A D T 3 S- 0 0 110 -2,-0.4 -1,-0.1 1,-0.3 3,-0.1 0.895 129.5 -50.6 52.4 46.4 34.9 18.0 40.1 194 317 A G T 3 S+ 0 0 66 1,-0.2 2,-0.4 -3,-0.0 -1,-0.3 0.519 117.6 105.1 74.6 5.1 33.7 15.9 43.0 195 318 A K E < -O 192 0E 119 -3,-1.7 -3,-2.6 2,-0.0 2,-0.3 -0.935 58.2-143.9-116.6 145.8 30.0 17.0 42.8 196 319 A T E -O 191 0E 95 -2,-0.4 2,-0.3 -5,-0.2 -5,-0.2 -0.765 17.9-177.4-106.6 153.3 27.2 14.9 41.4 197 320 A Y E -O 190 0E 51 -7,-2.5 -7,-2.6 -2,-0.3 2,-0.6 -0.998 30.5-130.2-147.5 145.3 24.3 16.1 39.4 198 321 A Q E -O 189 0E 121 -2,-0.3 -9,-0.2 -9,-0.2 -12,-0.1 -0.882 45.9-115.8 -88.9 121.1 21.1 14.8 37.8 199 322 A V - 0 0 0 -11,-2.1 -11,-0.2 -2,-0.6 47,-0.2 -0.327 35.1-161.1 -58.9 130.2 21.3 16.1 34.2 200 323 A K E -F 245 0A 80 45,-1.9 45,-2.7 -14,-0.0 47,-0.2 -0.930 16.9-123.1-117.2 142.4 18.5 18.5 33.6 201 324 A P E -F 244 0A 5 0, 0.0 2,-1.0 0, 0.0 43,-0.2 -0.503 35.2-109.0 -70.7 149.3 17.1 19.7 30.2 202 325 A I > - 0 0 0 41,-1.8 3,-1.6 1,-0.2 48,-0.2 -0.764 33.8-156.5 -82.8 108.0 17.2 23.5 29.8 203 326 A R T 3 S+ 0 0 141 46,-2.7 20,-0.3 -2,-1.0 21,-0.2 0.761 84.1 49.5 -64.6 -30.4 13.4 24.1 30.1 204 327 A N T 3 S+ 0 0 75 45,-0.4 2,-0.3 -3,-0.1 -1,-0.3 0.161 98.1 81.5 -97.7 19.0 13.2 27.4 28.2 205 328 A L < + 0 0 18 -3,-1.6 18,-0.6 38,-0.1 2,-0.3 -0.922 59.5 166.4-115.6 149.5 15.2 26.2 25.3 206 329 A N E -G 222 0A 52 -2,-0.3 36,-0.1 16,-0.2 2,-0.1 -0.974 36.3-105.8-153.9 164.3 13.6 24.1 22.5 207 330 A G E -G 221 0A 1 14,-3.1 14,-2.2 -2,-0.3 2,-0.3 -0.225 42.8-155.6 -80.0-176.7 14.0 22.7 19.0 208 331 A H E -GH 220 239A 7 31,-1.6 31,-3.2 12,-0.3 12,-0.2 -0.998 20.3 -99.9-163.7 153.8 12.0 24.3 16.2 209 332 A S E - H 0 238A 8 10,-2.4 8,-2.6 -2,-0.3 9,-0.4 -0.486 38.3-143.6 -74.7 153.1 10.4 24.0 12.8 210 333 A I E - H 0 237A 12 27,-2.6 27,-0.5 6,-0.2 2,-0.2 -0.958 17.8-177.0-120.2 137.0 12.4 25.4 10.0 211 334 A G B > -P 214 0F 24 3,-3.0 3,-2.3 -2,-0.4 -74,-0.3 -0.711 47.2 -59.5-122.6 178.4 11.0 27.2 6.9 212 335 A Q T 3 S- 0 0 89 1,-0.3 -76,-0.2 -2,-0.2 -77,-0.1 -0.436 124.3 -13.7 -65.1 123.1 12.5 28.7 3.8 213 336 A Y T 3 S+ 0 0 51 -78,-2.0 2,-0.4 -2,-0.3 -1,-0.3 0.686 119.8 110.9 54.5 22.1 15.0 31.4 4.8 214 337 A R B < -P 211 0F 68 -3,-2.3 -3,-3.0 -79,-0.4 3,-0.3 -0.772 46.3-177.5-131.8 88.8 13.3 31.0 8.2 215 338 A I S S+ 0 0 5 -2,-0.4 2,-0.5 74,-0.3 -1,-0.1 0.815 87.8 36.8 -53.7 -38.5 15.4 29.4 11.0 216 339 A H S S+ 0 0 58 1,-0.1 -1,-0.3 -6,-0.1 -6,-0.2 -0.846 71.6 176.9-118.5 93.6 12.4 29.5 13.4 217 340 A A - 0 0 29 -8,-2.6 -7,-0.2 -2,-0.5 -1,-0.1 0.579 57.2 -85.5 -79.3 -13.0 9.3 28.8 11.4 218 341 A G S S+ 0 0 64 1,-0.5 2,-0.3 -9,-0.4 -1,-0.1 0.069 97.0 89.2 138.4 -33.8 6.8 28.8 14.2 219 342 A K - 0 0 36 2,-0.0 -10,-2.4 -45,-0.0 -1,-0.5 -0.761 57.7-152.7 -96.3 145.5 6.5 25.5 15.9 220 343 A T E -G 208 0A 72 -2,-0.3 -12,-0.3 -12,-0.2 8,-0.1 -0.906 10.1-143.5-120.1 148.7 8.7 24.6 18.8 221 344 A V E -G 207 0A 2 -14,-2.2 -14,-3.1 -2,-0.4 20,-0.2 -0.927 25.0-148.2-109.7 104.1 9.9 21.2 20.1 222 345 A P E -G 206 0A 12 0, 0.0 -41,-0.2 0, 0.0 -16,-0.2 -0.324 10.7-152.0 -73.7 156.1 10.1 21.3 23.9 223 346 A I S S+ 0 0 0 -18,-0.6 2,-0.3 -20,-0.3 -17,-0.1 0.169 77.7 52.5-114.5 14.7 12.7 19.3 25.8 224 347 A I S S- 0 0 42 -21,-0.2 3,-0.5 -43,-0.1 -45,-0.3 -0.922 93.6 -92.1-136.3 164.8 10.6 18.9 29.0 225 348 A K S S+ 0 0 126 -47,-0.3 -2,-0.1 -2,-0.3 -49,-0.1 -0.191 94.7 60.6 -66.9 166.7 7.1 17.6 29.6 226 349 A G S S+ 0 0 76 1,-0.2 -1,-0.2 -51,-0.1 3,-0.1 0.420 73.0 124.4 97.1 -0.1 4.1 20.0 29.7 227 350 A G - 0 0 39 -3,-0.5 2,-0.2 -52,-0.2 -1,-0.2 0.165 65.8 -55.3 -79.8-163.5 4.1 21.5 26.2 228 351 A E - 0 0 130 -8,-0.1 -53,-1.5 1,-0.1 -1,-0.2 -0.549 31.0-140.8 -79.1 140.4 1.6 21.8 23.4 229 352 A A + 0 0 49 -2,-0.2 -1,-0.1 -55,-0.2 -53,-0.0 0.421 56.6 138.9 -79.2 1.3 -0.1 18.7 21.9 230 353 A T - 0 0 59 -57,-0.2 -56,-3.2 1,-0.1 -55,-0.3 -0.175 51.4-126.0 -42.9 139.3 0.2 20.4 18.5 231 354 A R B -N 173 0D 124 -58,-0.2 2,-0.3 -57,-0.1 -58,-0.2 -0.612 8.9-115.1 -99.3 151.9 1.2 17.7 16.0 232 355 A M - 0 0 0 -60,-2.3 -61,-3.0 -63,-0.4 2,-0.3 -0.630 39.1-143.1 -77.6 144.6 4.1 17.5 13.6 233 356 A E > - 0 0 111 -2,-0.3 3,-2.1 -63,-0.2 108,-0.1 -0.829 19.5 -90.3-119.8 151.6 2.9 17.5 10.0 234 357 A E T 3 S+ 0 0 70 -2,-0.3 108,-0.2 1,-0.3 3,-0.1 -0.252 112.1 22.4 -53.4 136.0 4.0 15.8 6.7 235 358 A G T 3 S+ 0 0 40 106,-2.9 -1,-0.3 1,-0.3 107,-0.1 0.250 91.6 129.2 88.7 -13.9 6.5 17.9 4.8 236 359 A E < - 0 0 39 -3,-2.1 105,-2.7 105,-0.2 2,-0.4 -0.337 47.6-145.1 -71.1 158.5 7.7 19.9 7.8 237 360 A V E -HI 210 340A 11 -27,-0.5 -27,-2.6 103,-0.2 2,-0.4 -0.985 18.4-166.7-124.5 133.9 11.4 20.2 8.7 238 361 A Y E -HI 209 339A 0 101,-2.1 101,-2.7 -2,-0.4 2,-0.8 -0.957 25.5-141.8-127.4 144.7 12.6 20.3 12.3 239 362 A A E -HI 208 338A 0 -31,-3.2 -31,-1.6 -2,-0.4 2,-0.9 -0.915 24.1-160.3 -93.5 108.6 15.8 21.2 14.2 240 363 A I E + I 0 337A 0 97,-2.8 97,-2.0 -2,-0.8 2,-0.4 -0.859 26.8 157.5 -92.2 104.8 15.8 18.6 16.9 241 364 A E E - I 0 336A 6 -2,-0.9 2,-0.3 95,-0.2 95,-0.2 -0.972 19.6-174.5-128.8 143.9 18.1 20.0 19.6 242 365 A T E - I 0 335A 0 93,-1.8 93,-1.4 -2,-0.4 2,-0.4 -0.956 7.6-157.9-132.1 156.7 18.3 19.4 23.3 243 366 A F E - I 0 334A 3 -2,-0.3 -41,-1.8 91,-0.2 2,-0.3 -0.999 4.7-162.3-134.8 133.9 20.4 21.0 25.9 244 367 A G E -FI 201 333A 0 89,-2.0 89,-2.3 -2,-0.4 2,-0.3 -0.897 11.4-171.8-116.0 148.7 21.4 19.5 29.3 245 368 A S E -FI 200 332A 0 -45,-2.7 -45,-1.9 -2,-0.3 87,-0.2 -0.980 34.2-152.2-141.3 151.5 22.7 21.5 32.3 246 369 A T S S+ 0 0 12 85,-1.9 86,-0.1 -2,-0.3 -48,-0.1 0.299 88.1 64.7 -95.2 5.0 24.2 21.0 35.7 247 370 A G S S- 0 0 9 84,-0.3 -2,-0.1 -47,-0.2 81,-0.0 0.302 117.7 -48.8-100.3-133.3 22.7 24.3 36.8 248 371 A K - 0 0 126 2,-0.3 3,-0.1 -48,-0.0 -3,-0.0 0.701 66.6-121.9 -78.3 -22.0 19.1 25.5 37.2 249 372 A G S S+ 0 0 2 1,-0.3 -46,-2.7 -49,-0.1 -45,-0.4 0.768 81.5 101.8 81.2 25.4 18.0 24.2 33.8 250 373 A V - 0 0 39 -48,-0.2 2,-0.3 -47,-0.2 -1,-0.3 -0.996 59.2-146.6-141.7 135.5 16.9 27.7 32.8 251 374 A V - 0 0 9 -2,-0.3 2,-0.3 75,-0.1 75,-0.2 -0.773 11.1-171.5-106.0 148.4 18.7 30.3 30.6 252 375 A H E -M 325 0C 89 73,-2.3 73,-2.6 -2,-0.3 2,-0.2 -0.927 37.0 -91.4-125.3 158.2 18.7 34.1 30.8 253 376 A D E +M 324 0C 110 -2,-0.3 2,-0.3 71,-0.2 71,-0.2 -0.470 57.7 161.1 -65.5 135.4 20.1 36.8 28.5 254 377 A D + 0 0 73 69,-2.1 -3,-0.0 -2,-0.2 0, 0.0 -0.993 29.7 12.0-157.5 150.6 23.6 37.7 29.4 255 378 A M S S- 0 0 96 -2,-0.3 2,-0.2 67,-0.1 70,-0.0 -0.083 98.4 -29.9 79.1-176.7 26.8 39.3 28.0 256 379 A E - 0 0 120 66,-0.1 2,-0.3 1,-0.1 -2,-0.1 -0.529 68.0-117.7 -73.9 141.1 27.2 41.5 24.9 257 380 A C + 0 0 21 -2,-0.2 -148,-0.1 1,-0.1 -1,-0.1 -0.604 41.6 160.7 -80.4 140.8 24.8 40.7 22.0 258 381 A S + 0 0 1 -150,-0.4 36,-1.1 63,-0.4 2,-0.4 0.534 52.3 77.4-129.0 -25.8 26.4 39.4 18.8 259 382 A H E +QR 293 321G 2 62,-0.6 62,-2.8 -151,-0.4 2,-0.3 -0.757 51.8 166.3 -99.3 137.2 23.5 37.7 17.0 260 383 A Y E -QR 292 320G 18 32,-2.6 32,-2.9 -2,-0.4 2,-0.3 -0.978 9.4-176.9-145.4 152.8 20.7 39.6 15.1 261 384 A M E - R 0 319G 16 58,-2.0 58,-2.6 -2,-0.3 30,-0.2 -0.942 31.2-110.4-156.9 133.4 18.0 38.7 12.7 262 385 A K E - R 0 318G 35 28,-0.5 2,-0.5 26,-0.4 56,-0.3 -0.275 44.1-103.7 -56.9 139.8 15.4 40.6 10.7 263 386 A N > - 0 0 48 54,-2.6 3,-1.2 53,-0.2 -1,-0.1 -0.620 28.4-142.9 -66.6 119.8 11.8 40.0 11.9 264 387 A F T 3 S+ 0 0 85 -2,-0.5 -1,-0.2 1,-0.2 -2,-0.1 0.792 94.9 50.5 -56.2 -31.8 10.4 37.6 9.2 265 388 A D T 3 S+ 0 0 120 2,-0.0 2,-0.3 -3,-0.0 -1,-0.2 0.555 84.1 101.5 -89.1 -8.7 6.9 39.2 9.4 266 389 A V < - 0 0 49 -3,-1.2 3,-0.1 51,-0.2 50,-0.0 -0.615 60.4-152.3 -81.0 132.8 7.9 42.8 9.0 267 390 A G - 0 0 54 -2,-0.3 2,-0.1 1,-0.2 -1,-0.1 -0.003 42.9 -44.2 -86.4-163.6 7.4 44.2 5.5 268 391 A H - 0 0 171 1,-0.0 -1,-0.2 -2,-0.0 0, 0.0 -0.431 55.8-168.6 -65.2 137.0 9.3 47.1 3.7 269 392 A V - 0 0 46 -2,-0.1 2,-0.3 -3,-0.1 -3,-0.0 -0.991 18.8-130.7-130.7 121.5 9.8 50.1 5.9 270 393 A P - 0 0 74 0, 0.0 2,-0.4 0, 0.0 7,-0.0 -0.559 26.4-170.2 -71.7 133.3 11.0 53.4 4.4 271 394 A I + 0 0 18 -2,-0.3 -2,-0.0 1,-0.1 9,-0.0 -0.988 22.0 175.4-130.2 126.2 13.9 54.9 6.3 272 395 A R + 0 0 201 -2,-0.4 -1,-0.1 5,-0.1 5,-0.0 0.780 54.0 104.3 -96.0 -33.8 15.3 58.4 5.8 273 396 A L S > S- 0 0 103 1,-0.1 4,-3.1 2,-0.1 5,-0.2 -0.326 72.0-140.8 -49.3 114.8 17.9 58.4 8.6 274 397 A P H > S+ 0 0 100 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.862 91.5 39.2 -55.8 -50.8 21.1 57.9 6.4 275 398 A R H > S+ 0 0 164 2,-0.2 4,-2.3 1,-0.2 5,-0.2 0.894 119.0 48.2 -70.6 -36.3 23.1 55.4 8.5 276 399 A T H > S+ 0 0 5 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.911 112.0 50.2 -68.2 -42.6 20.1 53.4 9.6 277 400 A K H X S+ 0 0 94 -4,-3.1 4,-2.2 2,-0.2 -2,-0.2 0.931 110.9 49.0 -59.1 -50.1 18.9 53.3 6.0 278 401 A H H X S+ 0 0 93 -4,-2.4 4,-2.5 -5,-0.2 -2,-0.2 0.925 111.0 49.2 -58.2 -42.2 22.2 52.1 4.7 279 402 A L H X S+ 0 0 2 -4,-2.3 4,-2.6 1,-0.2 -1,-0.2 0.917 109.5 50.9 -67.3 -41.8 22.5 49.4 7.3 280 403 A L H X S+ 0 0 11 -4,-2.3 4,-2.7 1,-0.2 -1,-0.2 0.899 110.6 50.4 -61.5 -38.2 19.0 48.1 6.6 281 404 A N H X S+ 0 0 74 -4,-2.2 4,-2.6 2,-0.2 -2,-0.2 0.917 109.3 51.0 -64.4 -42.6 19.9 48.0 2.9 282 405 A V H X S+ 0 0 9 -4,-2.5 4,-2.4 1,-0.2 5,-0.3 0.908 112.0 47.5 -60.7 -43.0 23.1 46.0 3.7 283 406 A I H X>S+ 0 0 0 -4,-2.6 4,-2.8 2,-0.2 5,-2.3 0.931 112.3 48.6 -64.7 -46.3 21.1 43.6 5.8 284 407 A N H <5S+ 0 0 50 -4,-2.7 -2,-0.2 3,-0.2 -1,-0.2 0.908 115.9 44.3 -59.6 -42.8 18.5 43.1 3.1 285 408 A E H <5S+ 0 0 135 -4,-2.6 -2,-0.2 -5,-0.2 -1,-0.2 0.902 126.4 27.6 -67.6 -43.7 21.1 42.6 0.4 286 409 A N H <5S+ 0 0 64 -4,-2.4 -2,-0.2 -5,-0.2 -3,-0.2 0.776 137.3 12.4 -97.1 -29.7 23.4 40.2 2.4 287 410 A F T ><5 - 0 0 20 -4,-2.8 3,-2.8 -5,-0.3 -3,-0.2 0.671 67.7-176.9-121.5 -29.1 21.2 38.4 4.9 288 411 A G T 3 > -Q 259 0G 0 -2,-0.3 4,-0.8 -34,-0.2 3,-0.7 -0.872 32.8-102.8-128.7 170.5 26.4 38.8 13.6 294 417 A R H >> S+ 0 0 32 -36,-1.1 4,-2.5 -2,-0.3 3,-0.9 0.859 118.5 60.9 -59.7 -39.9 28.5 42.0 14.1 295 418 A R H 3> S+ 0 0 14 -184,-0.3 4,-2.2 1,-0.3 -1,-0.2 0.846 100.5 55.9 -56.0 -34.6 31.6 40.3 12.7 296 419 A W H <4 S+ 0 0 9 -3,-0.7 4,-0.5 2,-0.2 -1,-0.3 0.748 107.4 48.4 -73.4 -22.2 29.7 39.7 9.5 297 420 A L H X<>S+ 0 0 0 -3,-0.9 5,-2.0 -4,-0.8 3,-0.9 0.911 109.9 51.5 -78.3 -45.3 29.1 43.5 9.2 298 421 A D H ><5S+ 0 0 56 -4,-2.5 3,-2.2 1,-0.3 -2,-0.2 0.923 106.3 55.3 -51.6 -50.4 32.7 44.3 9.9 299 422 A R T 3<5S+ 0 0 133 -4,-2.2 -1,-0.3 1,-0.3 -2,-0.2 0.733 101.2 57.7 -56.8 -28.7 33.8 41.9 7.2 300 423 A L T < 5S- 0 0 62 -3,-0.9 -1,-0.3 -4,-0.5 -2,-0.2 0.351 124.6-104.3 -85.2 5.3 31.6 43.8 4.7 301 424 A G T < 5S+ 0 0 63 -3,-2.2 2,-0.4 1,-0.3 -3,-0.2 0.627 72.0 147.4 82.8 13.1 33.5 46.9 5.5 302 425 A E < + 0 0 36 -5,-2.0 2,-0.3 -23,-0.0 -1,-0.3 -0.687 17.3 170.3 -83.8 138.6 30.8 48.5 7.7 303 426 A S + 0 0 62 -2,-0.4 -5,-0.0 1,-0.2 0, 0.0 -0.897 56.7 29.5-137.4 164.3 31.9 50.7 10.6 304 427 A K S S+ 0 0 148 -2,-0.3 4,-0.2 1,-0.1 -1,-0.2 0.939 78.6 128.3 52.3 49.4 30.0 53.0 13.0 305 428 A Y > + 0 0 20 -3,-0.2 4,-2.9 2,-0.1 5,-0.2 0.464 34.3 94.6-113.0 -2.7 26.9 50.9 12.6 306 429 A L H > S+ 0 0 87 1,-0.2 4,-2.4 2,-0.2 5,-0.1 0.876 88.0 44.8 -62.1 -43.3 26.0 50.2 16.3 307 430 A M H > S+ 0 0 122 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.919 114.3 50.7 -66.9 -42.5 23.6 53.1 16.7 308 431 A A H > S+ 0 0 4 2,-0.2 4,-2.5 -4,-0.2 -2,-0.2 0.926 111.1 48.8 -56.9 -44.4 22.0 52.2 13.3 309 432 A L H X S+ 0 0 2 -4,-2.9 4,-2.0 1,-0.2 -2,-0.2 0.929 111.0 50.0 -63.8 -43.1 21.6 48.5 14.5 310 433 A K H X S+ 0 0 108 -4,-2.4 4,-3.0 2,-0.2 -1,-0.2 0.898 109.0 52.8 -59.5 -43.9 20.1 49.7 17.8 311 434 A N H X S+ 0 0 48 -4,-2.6 4,-2.5 1,-0.2 6,-0.2 0.944 108.3 49.6 -56.5 -50.2 17.6 51.9 15.8 312 435 A L H <>S+ 0 0 0 -4,-2.5 5,-1.8 1,-0.2 6,-1.8 0.872 113.5 47.0 -58.4 -36.8 16.6 48.9 13.7 313 436 A C H ><5S+ 0 0 23 -4,-2.0 3,-1.5 4,-0.2 -2,-0.2 0.934 110.6 50.6 -70.1 -44.9 16.1 46.8 16.8 314 437 A D H 3<5S+ 0 0 110 -4,-3.0 -2,-0.2 1,-0.3 -1,-0.2 0.862 109.0 53.3 -63.0 -34.9 14.1 49.6 18.6 315 438 A L T 3<5S- 0 0 102 -4,-2.5 -1,-0.3 -5,-0.2 -2,-0.2 0.600 112.8-122.8 -73.2 -12.5 11.9 49.8 15.5 316 439 A G T < 5S+ 0 0 27 -3,-1.5 -3,-0.2 2,-0.3 -53,-0.2 0.576 84.8 113.7 78.4 7.8 11.3 46.1 15.7 317 440 A I S S- 0 0 80 -77,-0.2 3,-2.1 1,-0.1 -1,-0.2 -0.179 70.2 -85.5 -64.4 152.1 23.9 30.2 36.3 328 451 A K T 3 S+ 0 0 194 1,-0.3 -1,-0.1 -3,-0.1 3,-0.1 -0.229 116.1 24.7 -53.3 138.3 27.6 31.0 36.9 329 452 A G T 3 S+ 0 0 55 1,-0.3 -1,-0.3 -3,-0.1 2,-0.1 0.250 96.1 119.0 87.0 -14.5 29.6 27.8 37.5 330 453 A S < - 0 0 5 -3,-2.1 2,-0.4 -4,-0.0 -1,-0.3 -0.440 55.5-136.8 -82.8 161.4 27.1 25.5 35.7 331 454 A Y - 0 0 44 -227,-0.1 -85,-1.9 -2,-0.1 2,-0.3 -0.967 17.4-169.1-120.5 133.6 27.9 23.4 32.6 332 455 A T E - I 0 245A 0 -229,-1.9 2,-0.3 -2,-0.4 -87,-0.2 -0.938 2.3-170.0-123.3 146.4 25.7 23.0 29.5 333 456 A A E - I 0 244A 0 -89,-2.3 -89,-2.0 -2,-0.3 2,-0.3 -0.943 3.3-167.6-131.6 155.2 25.9 20.7 26.5 334 457 A Q E + I 0 243A 1 -2,-0.3 2,-0.4 -91,-0.2 -91,-0.2 -1.000 11.7 178.8-145.6 139.4 24.0 20.6 23.2 335 458 A F E + I 0 242A 11 -93,-1.4 -93,-1.8 -2,-0.3 2,-0.3 -0.989 16.9 175.0-137.1 142.8 23.5 18.2 20.3 336 459 A E E +EI 141 241A 0 -195,-2.3 -195,-1.6 -2,-0.4 2,-0.3 -0.997 12.0 178.4-152.0 141.8 21.3 19.0 17.3 337 460 A H E - I 0 240A 2 -97,-2.0 -97,-2.8 -2,-0.3 2,-0.4 -0.954 25.9-126.7-137.1 157.0 20.2 17.6 13.9 338 461 A T E - I 0 239A 0 -2,-0.3 12,-1.2 -99,-0.2 11,-0.4 -0.887 28.1-167.6-101.6 136.1 17.9 18.7 11.2 339 462 A I E - I 0 238A 0 -101,-2.7 -101,-2.1 -2,-0.4 2,-0.5 -0.944 14.3-143.1-125.1 147.3 15.3 16.2 10.1 340 463 A L E -JI 347 237A 0 7,-2.4 7,-2.4 -2,-0.3 2,-1.6 -0.951 8.7-147.2-109.3 123.0 13.0 16.2 7.0 341 464 A L E -J 346 0A 0 -105,-2.7 -106,-2.9 -2,-0.5 5,-0.2 -0.614 32.6-179.4 -86.6 76.5 9.5 14.8 7.5 342 465 A R - 0 0 10 -2,-1.6 3,-0.2 3,-1.2 -172,-0.1 -0.386 38.6-112.7 -76.3 156.4 9.2 13.3 4.1 343 466 A P S S+ 0 0 14 0, 0.0 -310,-0.1 0, 0.0 -1,-0.1 0.861 115.7 35.4 -55.7 -40.4 6.0 11.5 2.9 344 467 A T S S- 0 0 68 -312,-0.2 2,-0.3 1,-0.1 -317,-0.2 0.621 129.7 -16.8 -92.9 -13.8 7.7 8.1 2.6 345 468 A C - 0 0 13 -3,-0.2 -3,-1.2 -319,-0.1 2,-0.6 -0.981 65.4 -89.7-172.2 177.5 10.1 8.4 5.6 346 469 A K E -AJ 25 341A 5 -321,-2.8 -321,-2.8 -2,-0.3 2,-0.6 -0.944 37.4-159.6-106.9 121.0 11.9 10.5 8.2 347 470 A E E -AJ 24 340A 0 -7,-2.4 -7,-2.4 -2,-0.6 2,-2.1 -0.903 15.7-157.3-109.2 114.1 15.3 11.7 7.0 348 471 A V E > -A 23 0A 0 -325,-3.1 3,-1.8 -2,-0.6 -325,-1.6 -0.610 25.4-177.8 -80.6 80.1 17.9 12.7 9.6 349 472 A V T 3 S+ 0 0 0 -2,-2.1 -1,-0.2 -11,-0.4 -10,-0.2 0.780 71.3 46.3 -59.5 -33.5 19.5 14.8 6.9 350 473 A S T 3 S+ 0 0 0 -12,-1.2 -1,-0.3 -3,-0.2 -11,-0.1 0.344 80.4 129.2 -93.9 5.1 22.5 16.1 8.9 351 474 A R < + 0 0 50 -3,-1.8 2,-0.2 -13,-0.2 -297,-0.1 -0.337 33.9 177.1 -57.4 140.3 23.4 12.7 10.4 352 475 A G - 0 0 19 -330,-0.1 -2,-0.0 -298,-0.0 -1,-0.0 -0.737 48.8 -96.6-131.8-176.5 27.1 11.9 10.0 353 476 A D S S+ 0 0 140 -2,-0.2 -2,-0.1 1,-0.2 -299,-0.0 0.488 123.2 56.3 -79.1 -2.3 29.5 9.1 11.0 354 477 A D 0 0 50 -300,-0.0 -1,-0.2 0, 0.0 -3,-0.1 0.849 360.0 360.0 -94.9 -46.2 30.4 11.4 13.9 355 478 A Y 0 0 21 -213,-0.0 -2,-0.1 -197,-0.0 -4,-0.1 0.284 360.0 360.0-162.3 360.0 27.0 12.0 15.5 356 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 357 601 A X 0 0 15 0, 0.0 -141,-0.1 0, 0.0 -249,-0.1 0.000 360.0 360.0 360.0 360.0 19.6 28.5 16.0