==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=23-JUL-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 18-DEC-09 2KRJ . COMPND 2 MOLECULE: MACROPHAGE METALLOELASTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR I.BERTINI,A.BHAUMIK,G.DE PA PE,R.G.GRIFFIN,M.LELLI,J.R.LEWAN . 152 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9268.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 77 50.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 11 7.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 11.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 13 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 28 18.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 112 A H 0 0 225 0, 0.0 2,-0.3 0, 0.0 36,-0.0 0.000 360.0 360.0 360.0 165.2 -16.5 -13.4 4.4 2 113 A Y - 0 0 211 34,-0.1 2,-0.3 35,-0.0 37,-0.1 -0.889 360.0-151.0-117.7 147.7 -12.8 -14.4 3.7 3 114 A I + 0 0 32 -2,-0.3 2,-0.3 43,-0.0 0, 0.0 -0.891 13.4 179.2-118.4 148.2 -9.9 -12.2 2.8 4 115 A T - 0 0 34 -2,-0.3 44,-0.7 34,-0.1 2,-0.3 -0.998 6.0-165.9-148.4 144.4 -6.8 -13.0 0.7 5 116 A Y B -a 40 0A 18 34,-1.1 36,-0.9 -2,-0.3 2,-0.3 -0.848 3.4-172.9-127.7 164.0 -3.6 -11.2 -0.4 6 117 A R - 0 0 59 -2,-0.3 44,-0.4 42,-0.2 2,-0.3 -0.829 4.2-166.9-161.9 117.8 -0.9 -11.8 -2.9 7 118 A I + 0 0 40 -2,-0.3 44,-0.1 42,-0.1 -2,-0.0 -0.813 19.8 153.9-108.7 148.5 2.3 -9.8 -3.6 8 119 A N + 0 0 95 42,-0.6 2,-0.3 -2,-0.3 44,-0.3 -0.172 34.7 110.6-169.0 60.5 4.7 -10.1 -6.6 9 120 A N + 0 0 3 42,-0.1 2,-0.3 7,-0.1 42,-0.1 -0.996 28.2 172.5-144.6 135.7 6.6 -6.8 -7.2 10 121 A Y - 0 0 90 -2,-0.3 6,-0.1 42,-0.1 5,-0.0 -0.853 10.6-168.6-147.8 107.1 10.3 -5.9 -6.8 11 122 A T - 0 0 14 -2,-0.3 3,-0.3 1,-0.1 8,-0.1 -0.568 26.4-105.0 -94.2 158.6 11.8 -2.6 -8.0 12 123 A P S S+ 0 0 73 0, 0.0 80,-0.3 0, 0.0 -1,-0.1 0.014 97.1 49.3 -69.8-178.5 15.5 -1.7 -8.3 13 124 A D S S+ 0 0 114 78,-0.1 2,-0.3 1,-0.1 -2,-0.0 0.755 106.7 76.4 56.1 24.0 17.5 0.5 -6.0 14 125 A M S S- 0 0 29 -3,-0.3 -1,-0.1 79,-0.1 2,-0.1 -0.891 85.3-112.7-165.3 131.3 16.0 -1.6 -3.1 15 126 A N >> - 0 0 94 -2,-0.3 4,-1.4 1,-0.1 3,-1.2 -0.365 25.1-126.4 -66.1 142.0 16.6 -5.0 -1.7 16 127 A R H 3> S+ 0 0 172 1,-0.3 4,-1.8 2,-0.2 -1,-0.1 0.699 110.0 65.1 -61.4 -18.1 13.8 -7.6 -2.2 17 128 A E H 3> S+ 0 0 140 2,-0.2 4,-1.7 1,-0.2 -1,-0.3 0.844 99.3 50.0 -73.4 -34.8 13.9 -8.0 1.6 18 129 A D H <> S+ 0 0 41 -3,-1.2 4,-2.5 2,-0.2 -2,-0.2 0.921 113.3 44.4 -69.5 -45.6 12.7 -4.5 2.2 19 130 A V H X S+ 0 0 6 -4,-1.4 4,-2.2 2,-0.2 5,-0.4 0.881 109.4 57.8 -66.6 -39.1 9.8 -4.8 -0.2 20 131 A D H X S+ 0 0 70 -4,-1.8 4,-1.9 1,-0.2 -2,-0.2 0.950 117.4 31.4 -56.0 -53.7 8.9 -8.2 1.2 21 132 A Y H X S+ 0 0 128 -4,-1.7 4,-2.6 2,-0.2 5,-0.3 0.824 112.0 67.7 -74.7 -32.6 8.5 -6.9 4.7 22 133 A A H X S+ 0 0 0 -4,-2.5 4,-0.8 -5,-0.2 -2,-0.2 0.951 115.4 24.8 -51.2 -57.9 7.3 -3.5 3.5 23 134 A I H X S+ 0 0 11 -4,-2.2 4,-1.1 2,-0.2 3,-0.4 0.887 117.2 63.0 -75.9 -41.2 4.0 -4.8 2.1 24 135 A R H < S+ 0 0 127 -4,-1.9 4,-0.5 -5,-0.4 3,-0.4 0.857 108.0 44.3 -51.5 -38.1 3.9 -7.9 4.4 25 136 A K H >X S+ 0 0 68 -4,-2.6 4,-2.8 1,-0.2 3,-0.6 0.763 98.0 73.6 -78.4 -26.6 3.7 -5.5 7.3 26 137 A A H 3X S+ 0 0 0 -4,-0.8 4,-0.9 -3,-0.4 -1,-0.2 0.824 95.7 52.0 -55.8 -32.6 1.1 -3.3 5.5 27 138 A F H 3X S+ 0 0 25 -4,-1.1 4,-2.5 -3,-0.4 -1,-0.3 0.806 112.6 45.2 -74.4 -30.4 -1.4 -6.1 6.1 28 139 A Q H <> S+ 0 0 95 -3,-0.6 4,-2.4 -4,-0.5 -2,-0.2 0.957 108.9 51.7 -77.1 -55.1 -0.6 -6.2 9.9 29 140 A V H < S+ 0 0 7 -4,-2.8 110,-0.3 1,-0.2 -1,-0.2 0.781 121.6 37.7 -52.9 -27.4 -0.6 -2.4 10.5 30 141 A W H >< S+ 0 0 12 -4,-0.9 3,-2.1 -5,-0.3 -2,-0.2 0.911 114.3 49.7 -89.5 -53.8 -4.0 -2.4 8.8 31 142 A S H >< S+ 0 0 41 -4,-2.5 3,-1.4 1,-0.3 -2,-0.2 0.714 89.9 86.8 -59.0 -19.5 -5.5 -5.6 10.1 32 143 A N T 3< S+ 0 0 103 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.1 0.800 104.4 25.5 -50.9 -30.1 -4.5 -4.4 13.6 33 144 A V T < S+ 0 0 20 -3,-2.1 -1,-0.3 -5,-0.1 -2,-0.1 -0.449 106.3 92.1-134.9 61.5 -7.8 -2.6 13.6 34 145 A T < - 0 0 26 -3,-1.4 114,-0.2 2,-0.1 115,-0.1 -0.979 66.6-135.8-156.3 140.5 -10.1 -4.5 11.3 35 146 A P S S+ 0 0 87 0, 0.0 113,-0.1 0, 0.0 -4,-0.1 0.619 75.9 110.0 -69.8 -12.5 -12.7 -7.3 11.6 36 147 A L - 0 0 50 1,-0.1 2,-0.2 -34,-0.0 -2,-0.1 0.098 63.3-129.3 -54.6 175.9 -11.2 -8.8 8.4 37 148 A K - 0 0 122 2,-0.0 2,-0.4 -36,-0.0 -1,-0.1 -0.464 13.5-107.5-118.2-169.0 -9.2 -12.1 8.5 38 149 A F + 0 0 163 -2,-0.2 2,-0.2 2,-0.0 -34,-0.1 -0.991 34.7 158.4-130.7 134.4 -5.8 -13.3 7.3 39 150 A S - 0 0 62 -2,-0.4 2,-1.2 -37,-0.1 -34,-1.1 -0.621 18.5-164.7-156.9 89.5 -5.1 -15.8 4.5 40 151 A K B -a 5 0A 104 -36,-0.2 2,-0.4 -2,-0.2 -34,-0.1 -0.650 16.1-160.8 -80.6 97.9 -1.7 -15.8 2.8 41 152 A I - 0 0 63 -2,-1.2 3,-0.2 -36,-0.9 5,-0.1 -0.661 14.5-160.7 -83.5 130.6 -2.2 -17.7 -0.4 42 153 A N S S+ 0 0 153 -2,-0.4 2,-0.3 1,-0.3 -1,-0.1 0.782 83.4 17.5 -78.4 -28.5 1.0 -19.1 -2.0 43 154 A T S S+ 0 0 115 1,-0.2 -1,-0.3 2,-0.0 -37,-0.0 -0.931 105.3 52.7-149.6 120.9 -0.7 -19.5 -5.4 44 155 A G - 0 0 34 -2,-0.3 -1,-0.2 -3,-0.2 -3,-0.1 0.595 67.2-132.2 118.9 85.3 -3.9 -17.9 -6.6 45 156 A M - 0 0 100 1,-0.1 2,-0.2 -3,-0.1 4,-0.1 0.007 26.9-168.3 -54.8 167.3 -4.5 -14.1 -6.4 46 157 A A - 0 0 30 2,-0.8 -1,-0.1 -42,-0.1 -40,-0.1 -0.635 49.1 -50.4-140.6-162.0 -7.7 -12.7 -5.0 47 158 A D S S+ 0 0 93 -2,-0.2 2,-0.7 1,-0.1 -42,-0.1 0.759 123.0 69.7 -50.8 -25.2 -9.7 -9.5 -4.7 48 159 A I + 0 0 15 -44,-0.7 -2,-0.8 35,-0.1 2,-0.3 -0.871 68.8 174.4-102.5 114.4 -6.4 -8.0 -3.4 49 160 A L E -b 83 0B 44 33,-2.5 35,-1.0 -2,-0.7 2,-0.3 -0.816 15.0-165.5-117.2 158.0 -3.7 -7.6 -6.0 50 161 A V E +b 84 0B 9 -44,-0.4 -42,-0.6 -2,-0.3 2,-0.3 -0.879 22.9 144.0-148.0 111.0 -0.2 -6.1 -5.9 51 162 A V E -b 85 0B 57 33,-1.5 35,-1.2 -2,-0.3 2,-0.4 -0.998 35.1-135.9-148.5 144.8 1.9 -5.2 -9.0 52 163 A F E +b 86 0B 58 -2,-0.3 2,-0.3 -44,-0.3 35,-0.2 -0.847 29.5 165.4-104.7 136.7 4.3 -2.5 -10.0 53 164 A A E -b 87 0B 2 33,-1.6 35,-2.0 -2,-0.4 2,-0.6 -0.912 35.7-114.3-142.4 168.4 4.3 -0.8 -13.4 54 165 A R - 0 0 98 -2,-0.3 8,-0.1 33,-0.3 33,-0.1 -0.918 64.9 -66.4-112.2 111.8 5.6 2.3 -15.2 55 166 A G S S+ 0 0 1 -2,-0.6 2,-0.7 9,-0.4 9,-0.1 -0.212 120.9 23.7 50.4-128.6 3.1 4.8 -16.3 56 167 A A - 0 0 77 6,-0.1 2,-0.3 1,-0.1 -2,-0.1 -0.563 65.8-168.1 -71.5 110.9 0.8 3.4 -19.0 57 168 A H - 0 0 112 -2,-0.7 2,-1.5 -4,-0.1 -1,-0.1 -0.194 58.2 -89.4 -92.5 41.9 0.9 -0.4 -18.6 58 169 A G S S+ 0 0 77 -2,-0.3 -1,-0.1 1,-0.2 -2,-0.1 -0.305 119.5 11.5 84.9 -53.9 -0.8 -1.0 -21.9 59 170 A D S S+ 0 0 158 -2,-1.5 -1,-0.2 2,-0.0 2,-0.1 0.009 110.5 97.7-145.1 28.8 -4.3 -0.9 -20.5 60 171 A D S S- 0 0 83 -5,-0.1 2,-0.9 0, 0.0 -2,-0.1 -0.332 84.0 -84.9-107.1-169.5 -3.7 0.4 -16.9 61 172 A H - 0 0 149 -2,-0.1 -6,-0.1 -5,-0.1 -5,-0.1 -0.785 44.8-147.7-104.8 90.3 -4.0 3.8 -15.3 62 173 A A + 0 0 54 -2,-0.9 -6,-0.1 1,-0.1 -8,-0.0 -0.136 21.5 174.2 -53.6 149.5 -0.6 5.6 -15.9 63 174 A F - 0 0 38 1,-0.2 2,-0.3 7,-0.1 -1,-0.1 0.578 32.8-100.4-120.8 -82.9 0.5 8.0 -13.1 64 175 A D - 0 0 105 5,-0.4 -9,-0.4 4,-0.1 -1,-0.2 -0.976 32.0 -75.1 174.0-170.1 3.9 9.6 -13.4 65 176 A G S > S- 0 0 19 -2,-0.3 3,-1.2 1,-0.2 25,-0.2 -0.085 80.4 -26.4 -97.6-160.7 7.6 9.5 -12.3 66 177 A K T 3 S+ 0 0 155 23,-0.3 -1,-0.2 1,-0.2 3,-0.1 -0.291 130.6 25.2 -53.0 118.6 9.3 10.4 -9.1 67 178 A G T 3 S+ 0 0 29 1,-0.3 3,-0.2 -3,-0.1 -1,-0.2 -0.368 107.9 72.0 123.6 -54.4 7.2 13.2 -7.5 68 179 A G S < S- 0 0 39 -3,-1.2 2,-1.5 1,-0.2 -1,-0.3 0.550 111.6 -20.9 -67.8-137.7 3.8 12.6 -8.8 69 180 A I - 0 0 81 1,-0.2 -5,-0.4 -3,-0.1 3,-0.2 -0.593 58.7-173.9 -78.0 90.8 1.6 9.6 -7.7 70 181 A L S S- 0 0 23 -2,-1.5 17,-2.1 1,-0.3 2,-0.2 0.830 74.8 -19.3 -53.0 -33.5 4.2 7.2 -6.4 71 182 A A + 0 0 11 15,-0.2 2,-0.4 -3,-0.1 -1,-0.3 -0.710 62.7 178.4-179.1 124.0 1.3 4.7 -6.0 72 183 A H - 0 0 52 13,-0.5 2,-0.5 -3,-0.2 36,-0.1 -0.938 10.4-162.4-138.6 113.8 -2.5 4.9 -5.8 73 184 A A - 0 0 2 -2,-0.4 11,-0.1 35,-0.2 8,-0.0 -0.841 21.0-128.5 -99.3 125.0 -4.8 1.9 -5.5 74 185 A F - 0 0 147 -2,-0.5 8,-0.6 9,-0.2 9,-0.2 -0.131 43.5 -71.9 -63.6 164.2 -8.4 2.4 -6.4 75 186 A G - 0 0 25 6,-0.1 7,-1.1 37,-0.1 8,-0.4 0.099 60.6 -89.2 -50.6 169.9 -11.2 1.3 -4.0 76 187 A P S S+ 0 0 73 0, 0.0 6,-0.3 0, 0.0 2,-0.3 0.135 70.1 99.4 -69.7-169.4 -11.9 -2.4 -3.4 77 188 A G S S- 0 0 36 4,-0.7 2,-0.3 35,-0.2 35,-0.0 -0.939 72.9 -13.7 129.7-152.0 -14.4 -4.6 -5.3 78 189 A S S > S- 0 0 112 -2,-0.3 3,-2.5 2,-0.0 2,-0.5 -0.639 111.2 -27.8 -91.9 148.5 -14.1 -7.1 -8.1 79 190 A G T 3 S+ 0 0 56 1,-0.3 -30,-0.1 -2,-0.3 -2,-0.1 -0.296 146.9 27.3 52.8-102.5 -11.0 -7.6 -10.2 80 191 A I T > S+ 0 0 120 -2,-0.5 3,-2.3 2,-0.1 2,-0.6 0.847 98.4 104.7 -56.1 -35.4 -9.4 -4.1 -10.1 81 192 A G T < S+ 0 0 6 -3,-2.5 -4,-0.7 1,-0.3 -6,-0.1 -0.291 93.9 13.7 -52.7 100.5 -11.1 -3.6 -6.7 82 193 A G T 3 S+ 0 0 1 -7,-1.1 -33,-2.5 -8,-0.6 2,-0.4 0.654 92.2 145.6 104.3 21.7 -8.2 -4.0 -4.4 83 194 A D E < -b 49 0B 43 -3,-2.3 2,-0.4 -8,-0.4 -1,-0.3 -0.743 39.1-140.3 -95.1 139.4 -5.4 -3.7 -6.9 84 195 A A E -b 50 0B 9 -35,-1.0 -33,-1.5 -2,-0.4 2,-0.5 -0.792 11.4-164.6-100.7 140.4 -2.0 -2.1 -6.0 85 196 A H E -b 51 0B 12 -2,-0.4 2,-0.5 -35,-0.1 -13,-0.5 -0.940 7.4-179.5-128.6 110.5 -0.1 0.1 -8.4 86 197 A F E -b 52 0B 2 -35,-1.2 -33,-1.6 -2,-0.5 -15,-0.2 -0.938 31.1-121.0-113.7 120.2 3.5 1.0 -7.8 87 198 A D E -b 53 0B 2 -17,-2.1 -33,-0.3 -2,-0.5 5,-0.1 -0.364 19.4-163.1 -59.0 124.0 5.4 3.2 -10.2 88 199 A E S S+ 0 0 62 -35,-2.0 4,-0.2 1,-0.2 -34,-0.2 0.934 90.0 51.2 -74.7 -48.8 8.4 1.4 -11.5 89 200 A D S S+ 0 0 88 -36,-0.2 -23,-0.3 -25,-0.1 -1,-0.2 0.683 97.3 97.3 -62.4 -16.7 10.3 4.4 -12.8 90 201 A E S S- 0 0 13 -26,-0.2 2,-0.4 -25,-0.2 -24,-0.1 0.191 84.1-108.6 -59.3-172.0 9.8 5.9 -9.3 91 202 A F - 0 0 105 -26,-0.1 8,-0.6 -80,-0.0 2,-0.2 -0.843 31.3-165.2-130.9 95.9 12.4 5.7 -6.6 92 203 A W E +c 99 0C 6 -2,-0.4 2,-0.3 -80,-0.3 8,-0.2 -0.494 14.6 170.6 -79.7 148.6 11.7 3.3 -3.7 93 204 A T E -c 100 0C 28 6,-2.5 8,-2.1 1,-0.2 -79,-0.1 -0.908 33.3 -83.7-148.5 174.3 13.6 3.5 -0.5 94 205 A T - 0 0 51 -2,-0.3 -1,-0.2 6,-0.2 7,-0.1 0.098 62.0 -78.4 -69.6-171.2 13.7 2.2 3.1 95 206 A H S S+ 0 0 45 1,-0.2 5,-0.1 5,-0.2 -1,-0.1 0.731 135.6 42.2 -63.9 -21.5 11.7 3.6 6.0 96 207 A S S S+ 0 0 68 3,-0.1 -1,-0.2 35,-0.1 35,-0.1 0.887 100.3 79.5 -90.6 -49.2 14.3 6.4 6.2 97 208 A G S S- 0 0 26 2,-0.1 -4,-0.2 35,-0.0 35,-0.0 0.096 97.2 -91.9 -52.1 172.4 14.8 7.2 2.5 98 209 A G S S+ 0 0 47 1,-0.2 2,-0.9 -6,-0.1 -6,-0.1 0.957 113.3 48.2 -51.7 -88.9 12.2 9.3 0.6 99 210 A T E S-c 92 0C 13 -8,-0.6 -6,-2.5 1,-0.1 2,-0.8 -0.403 84.2-148.4 -60.2 99.6 9.7 6.9 -0.8 100 211 A N E > -c 93 0C 2 -2,-0.9 4,-3.0 30,-0.2 5,-0.4 -0.622 9.2-162.8 -76.5 107.9 9.0 4.7 2.2 101 212 A L H > S+ 0 0 0 -8,-2.1 4,-1.7 -2,-0.8 -1,-0.2 0.861 91.2 44.7 -57.4 -36.9 8.2 1.2 0.9 102 213 A F H > S+ 0 0 9 2,-0.2 4,-1.6 3,-0.1 5,-0.2 0.990 117.6 39.4 -71.1 -64.3 6.6 0.4 4.2 103 214 A L H >> S+ 0 0 14 1,-0.2 4,-1.8 2,-0.2 3,-0.5 0.922 117.9 50.9 -51.7 -49.5 4.5 3.6 4.8 104 215 A T H 3X S+ 0 0 23 -4,-3.0 4,-3.0 1,-0.3 3,-0.4 0.926 106.0 54.3 -55.3 -48.8 3.6 3.7 1.1 105 216 A A H 3X S+ 0 0 2 -4,-1.7 4,-1.8 -5,-0.4 -1,-0.3 0.819 109.8 49.1 -55.8 -31.9 2.4 0.1 1.1 106 217 A V H X>S+ 0 0 0 -4,-1.1 4,-1.8 1,-0.2 3,-1.4 0.906 102.4 52.1 -68.7 -42.6 -5.6 1.4 2.7 111 222 A H H 3<5S+ 0 0 8 -4,-1.4 -1,-0.2 1,-0.3 -2,-0.2 0.751 107.3 55.7 -65.2 -23.7 -7.2 3.0 -0.3 112 223 A S T 3<5S+ 0 0 5 -4,-1.0 -1,-0.3 -37,-0.2 -35,-0.2 -0.043 113.2 40.9 -98.8 30.4 -7.9 -0.5 -1.6 113 224 A L T <45S- 0 0 31 -3,-1.4 -2,-0.2 2,-0.1 -3,-0.1 0.494 131.3 -52.7-136.4 -61.6 -9.8 -1.5 1.6 114 225 A G T <5S+ 0 0 39 -4,-1.8 2,-0.3 -39,-0.1 -3,-0.2 0.212 87.3 124.2 179.7 32.4 -12.1 1.2 2.9 115 226 A L < - 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