==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER H3K4ME3 BINDING PROTEIN, TRANSFERASE 29-NOV-09 3KVA . COMPND 2 MOLECULE: JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,X.CHENG . 366 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16939.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 264 72.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 63 17.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 29 7.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 45 12.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 106 29.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 1 1 1 2 0 1 0 1 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 2 2 1 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 114 A P 0 0 143 0, 0.0 2,-0.7 0, 0.0 212,-0.1 0.000 360.0 360.0 360.0 132.7 -63.7 20.6 21.6 2 115 A V - 0 0 44 210,-0.4 2,-0.3 6,-0.1 212,-0.0 -0.907 360.0-147.7-104.0 109.4 -61.8 19.5 18.5 3 116 A Q > - 0 0 76 -2,-0.7 3,-1.3 1,-0.1 6,-0.4 -0.561 21.9-105.0 -80.6 138.3 -58.1 19.0 19.3 4 117 A A T 3 S+ 0 0 3 207,-1.9 -1,-0.1 -2,-0.3 3,-0.1 -0.304 103.4 21.1 -60.2 140.3 -55.4 19.7 16.8 5 118 A G T 3 S+ 0 0 8 1,-0.3 -1,-0.2 81,-0.1 80,-0.2 -0.016 93.5 123.8 93.0 -30.7 -53.9 16.6 15.2 6 119 A T S <> S- 0 0 34 -3,-1.3 4,-2.4 79,-0.3 -1,-0.3 -0.139 76.9-108.2 -66.0 159.4 -56.8 14.2 16.1 7 120 A R H > S+ 0 0 207 1,-0.2 4,-0.9 2,-0.2 -1,-0.1 0.788 121.7 49.8 -55.7 -31.2 -58.8 12.1 13.5 8 121 A T H > S+ 0 0 79 2,-0.2 4,-1.8 1,-0.2 3,-0.3 0.900 107.6 51.1 -75.1 -45.9 -61.7 14.5 14.0 9 122 A F H > S+ 0 0 11 -6,-0.4 4,-2.0 1,-0.2 -2,-0.2 0.892 110.2 52.3 -57.7 -40.3 -59.7 17.6 13.5 10 123 A I H X S+ 0 0 5 -4,-2.4 4,-2.3 2,-0.2 -1,-0.2 0.777 102.3 57.8 -68.9 -28.4 -58.4 16.1 10.3 11 124 A K H X S+ 0 0 158 -4,-0.9 4,-1.0 -3,-0.3 -1,-0.2 0.940 111.4 42.5 -66.4 -45.0 -61.9 15.3 9.0 12 125 A E H X S+ 0 0 76 -4,-1.8 4,-2.1 2,-0.2 -2,-0.2 0.856 114.5 50.7 -68.1 -37.3 -62.8 19.0 9.3 13 126 A L H < S+ 0 0 1 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.900 110.6 48.6 -67.7 -42.2 -59.4 20.1 7.8 14 127 A R H < S+ 0 0 105 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.713 114.6 46.8 -71.9 -20.7 -59.7 17.8 4.9 15 128 A S H < S+ 0 0 77 -4,-1.0 -2,-0.2 -5,-0.1 -1,-0.2 0.846 86.4 95.2 -91.9 -37.6 -63.3 19.0 4.1 16 129 A R < - 0 0 66 -4,-2.1 2,-0.7 -5,-0.1 0, 0.0 -0.196 67.5-142.5 -52.1 144.7 -62.9 22.8 4.4 17 130 A V - 0 0 137 3,-0.0 -1,-0.1 207,-0.0 3,-0.1 -0.851 23.9-167.7-115.8 92.5 -62.4 24.4 0.9 18 131 A F - 0 0 26 -2,-0.7 205,-0.1 1,-0.2 3,-0.1 -0.285 35.3 -82.6 -76.6 162.4 -59.9 27.2 1.5 19 132 A P - 0 0 36 0, 0.0 205,-2.3 0, 0.0 -1,-0.2 -0.402 60.0 -99.5 -63.5 144.0 -59.1 29.9 -1.0 20 133 A S B > -a 224 0A 55 203,-0.2 3,-1.7 1,-0.1 4,-0.2 -0.354 15.3-130.9 -67.0 144.2 -56.5 28.6 -3.4 21 134 A A G >> S+ 0 0 3 203,-2.1 4,-2.8 1,-0.3 3,-1.6 0.647 101.0 82.2 -66.8 -13.2 -52.8 29.5 -2.9 22 135 A D G 34 S+ 0 0 95 1,-0.3 -1,-0.3 202,-0.3 5,-0.1 0.665 76.1 70.9 -65.2 -16.7 -52.9 30.4 -6.6 23 136 A E G <4 S+ 0 0 137 -3,-1.7 -1,-0.3 1,-0.1 -2,-0.2 0.730 119.1 11.0 -73.0 -20.6 -54.4 33.7 -5.6 24 137 A I T <4 S+ 0 0 38 -3,-1.6 -2,-0.2 -4,-0.2 -1,-0.1 0.664 102.9 91.4-129.3 -31.3 -51.1 34.9 -4.1 25 138 A I < - 0 0 18 -4,-2.8 2,-0.5 20,-0.1 22,-0.2 -0.329 62.2-134.7 -74.5 156.8 -48.2 32.6 -4.9 26 139 A I E -b 47 0A 63 20,-1.9 22,-3.0 19,-0.1 2,-0.5 -0.940 11.6-153.6-111.7 125.9 -45.9 33.1 -7.9 27 140 A K E +b 48 0A 132 -2,-0.5 2,-0.3 20,-0.2 22,-0.2 -0.880 29.5 155.0-100.4 125.6 -45.0 30.1 -10.1 28 141 A M - 0 0 10 20,-2.4 2,-0.2 -2,-0.5 -2,-0.0 -0.904 42.4 -93.4-144.1 172.2 -41.7 30.5 -11.9 29 142 A H >> - 0 0 107 -2,-0.3 4,-1.4 20,-0.1 3,-1.0 -0.554 39.6-111.4 -85.8 153.8 -38.8 28.6 -13.5 30 143 A G T 34 S+ 0 0 7 23,-0.7 24,-0.2 21,-0.3 -1,-0.1 0.765 119.7 54.0 -53.6 -26.4 -35.7 27.8 -11.5 31 144 A S T 34 S+ 0 0 69 22,-0.2 -1,-0.3 1,-0.2 23,-0.1 0.802 102.2 55.7 -78.9 -31.4 -33.9 30.2 -13.8 32 145 A Q T <4 S+ 0 0 99 -3,-1.0 2,-1.7 1,-0.1 -2,-0.2 0.815 86.2 88.4 -70.6 -30.5 -36.2 33.1 -13.1 33 146 A L < + 0 0 11 -4,-1.4 2,-0.3 4,-0.1 -1,-0.1 -0.496 61.7 146.8 -74.1 86.1 -35.7 32.9 -9.4 34 147 A T > - 0 0 58 -2,-1.7 4,-2.5 1,-0.1 5,-0.2 -0.832 62.5-119.5-121.9 159.2 -32.7 35.1 -9.0 35 148 A Q H > S+ 0 0 67 -2,-0.3 4,-2.8 1,-0.2 5,-0.1 0.877 118.1 55.7 -61.5 -34.6 -31.4 37.5 -6.3 36 149 A R H > S+ 0 0 207 2,-0.2 4,-0.7 1,-0.2 -1,-0.2 0.949 108.2 47.4 -61.0 -50.1 -31.7 40.2 -8.9 37 150 A Y H >> S+ 0 0 47 1,-0.2 4,-2.7 -5,-0.2 3,-1.4 0.947 113.5 47.4 -55.7 -53.0 -35.4 39.4 -9.5 38 151 A L H 3X S+ 0 0 1 -4,-2.5 4,-2.9 1,-0.3 -2,-0.2 0.901 104.9 59.1 -58.1 -45.4 -36.1 39.3 -5.8 39 152 A E H 3< S+ 0 0 46 -4,-2.8 -1,-0.3 -5,-0.2 275,-0.2 0.638 117.1 33.7 -61.0 -14.6 -34.3 42.6 -5.1 40 153 A K H << S+ 0 0 76 -3,-1.4 -2,-0.2 -4,-0.7 -1,-0.2 0.823 129.6 30.4-103.7 -56.1 -36.7 44.3 -7.5 41 154 A H H < S- 0 0 126 -4,-2.7 3,-0.2 -5,-0.2 -3,-0.2 0.674 107.3-131.9 -78.3 -19.6 -40.0 42.5 -7.1 42 155 A G < - 0 0 24 -4,-2.9 2,-0.3 -5,-0.5 3,-0.1 -0.015 10.8-102.1 86.4 163.4 -39.4 41.6 -3.5 43 156 A F S S+ 0 0 5 1,-0.1 194,-0.4 -4,-0.1 -1,-0.1 -0.657 72.4 127.1-123.3 70.3 -39.8 38.3 -1.7 44 157 A D + 0 0 94 -2,-0.3 -1,-0.1 -3,-0.2 -2,-0.1 0.413 64.0 38.9-108.9 -1.8 -43.1 39.0 0.0 45 158 A V S S- 0 0 36 -3,-0.1 -20,-0.1 147,-0.1 192,-0.1 -0.959 95.5 -78.4-144.0 160.9 -45.1 35.9 -1.0 46 159 A P - 0 0 0 0, 0.0 -20,-1.9 0, 0.0 2,-0.5 -0.315 40.9-149.7 -61.9 141.6 -44.5 32.2 -1.5 47 160 A I E -bC 26 234A 2 187,-1.9 187,-2.7 -22,-0.2 2,-0.4 -0.963 6.5-154.4-115.7 130.1 -42.8 31.2 -4.8 48 161 A M E -bC 27 233A 10 -22,-3.0 -20,-2.4 -2,-0.5 185,-0.2 -0.901 10.1-172.8-108.5 132.2 -43.6 27.9 -6.4 49 162 A V E - C 0 232A 0 183,-2.8 183,-2.2 -2,-0.4 -20,-0.1 -0.920 1.9-172.5-124.6 98.9 -41.1 26.1 -8.7 50 163 A P S S+ 0 0 54 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 0.900 73.2 41.1 -58.9 -48.5 -42.8 23.0 -10.2 51 164 A K S S- 0 0 118 2,-0.1 -21,-0.3 180,-0.1 180,-0.1 -0.858 76.5-138.1-104.3 141.7 -39.7 21.5 -11.9 52 165 A L > + 0 0 63 -2,-0.4 3,-1.8 178,-0.2 5,-0.4 0.394 57.9 135.7 -79.5 6.5 -36.3 21.5 -10.1 53 166 A D T 3 S+ 0 0 81 1,-0.3 -23,-0.7 2,-0.1 -22,-0.2 -0.351 76.2 1.4 -58.9 123.2 -34.6 22.5 -13.4 54 167 A D T 3 S+ 0 0 114 -24,-0.2 -1,-0.3 -2,-0.1 -2,-0.1 0.436 95.2 110.6 80.2 2.0 -32.0 25.3 -12.7 55 168 A L S < S- 0 0 4 -3,-1.8 75,-3.4 2,-0.2 76,-0.5 0.751 82.8-125.7 -78.9 -20.6 -32.5 25.6 -8.9 56 169 A G + 0 0 30 -4,-0.4 2,-0.7 1,-0.3 -3,-0.1 0.518 64.0 145.3 85.5 6.7 -29.1 24.1 -8.3 57 170 A L - 0 0 12 -5,-0.4 2,-0.4 72,-0.1 -1,-0.3 -0.705 25.8-178.9 -84.4 113.0 -31.0 21.7 -6.1 58 171 A R B +L 127 0B 136 69,-1.8 69,-2.4 -2,-0.7 0, 0.0 -0.912 13.5 140.7-114.8 138.2 -29.5 18.2 -6.2 59 172 A L - 0 0 27 -2,-0.4 67,-0.2 67,-0.2 66,-0.0 -0.975 50.3 -63.3-170.3 158.0 -30.9 15.2 -4.3 60 173 A P - 0 0 18 0, 0.0 65,-0.0 0, 0.0 4,-0.0 -0.003 63.3 -92.8 -45.1 145.9 -31.6 11.4 -4.4 61 174 A S > - 0 0 69 1,-0.1 3,-3.5 2,-0.1 121,-0.1 -0.133 44.0 -91.6 -61.1 157.9 -34.1 10.0 -7.0 62 175 A P T 3 S+ 0 0 80 0, 0.0 -1,-0.1 0, 0.0 167,-0.0 0.522 124.5 64.3 -47.7 -9.6 -37.8 9.6 -6.2 63 176 A T T 3 + 0 0 115 2,-0.1 2,-0.3 120,-0.0 -2,-0.1 0.514 66.3 122.7 -96.4 -5.8 -37.0 6.0 -5.1 64 177 A F < - 0 0 12 -3,-3.5 2,-0.1 1,-0.1 118,-0.0 -0.411 53.7-154.7 -58.4 118.3 -34.8 7.1 -2.2 65 178 A S > - 0 0 39 -2,-0.3 4,-1.5 1,-0.1 5,-0.1 -0.342 30.3-109.3 -96.2 176.9 -36.6 5.3 0.7 66 179 A V H > S+ 0 0 5 1,-0.2 4,-1.2 2,-0.2 32,-0.1 0.746 120.4 58.5 -71.7 -26.5 -37.0 5.7 4.4 67 180 A M H > S+ 0 0 65 2,-0.2 4,-1.4 1,-0.2 -1,-0.2 0.888 102.9 51.4 -70.1 -41.4 -34.8 2.6 4.7 68 181 A D H > S+ 0 0 57 1,-0.2 4,-2.6 2,-0.2 5,-0.3 0.899 104.6 57.2 -62.7 -42.1 -32.0 4.3 2.8 69 182 A V H X S+ 0 0 0 -4,-1.5 4,-1.7 1,-0.3 5,-0.4 0.876 105.6 50.9 -57.6 -37.1 -32.2 7.3 5.2 70 183 A E H X>S+ 0 0 29 -4,-1.2 4,-2.0 3,-0.2 5,-0.7 0.842 112.3 47.3 -70.1 -32.9 -31.6 5.0 8.1 71 184 A R H <5S+ 0 0 74 -4,-1.4 -2,-0.2 -3,-0.2 -3,-0.1 0.995 116.3 40.9 -67.9 -66.6 -28.5 3.6 6.3 72 185 A Y H <5S+ 0 0 103 -4,-2.6 49,-0.8 1,-0.2 50,-0.5 0.699 128.5 32.7 -54.4 -25.6 -27.0 6.9 5.3 73 186 A V H <5S- 0 0 20 -4,-1.7 -1,-0.2 -5,-0.3 -3,-0.2 0.812 111.2-111.1-101.9 -39.9 -27.8 8.5 8.7 74 187 A G T ><5 - 0 0 22 -4,-2.0 3,-2.1 -5,-0.4 20,-0.3 0.611 10.3-121.5 105.1 102.8 -27.5 5.6 11.1 75 188 A G T 3 > -DE 88 110A 6 5,-2.7 5,-1.7 -2,-0.5 4,-0.7 -0.799 22.2-169.0 -87.2 95.3 -47.2 12.4 18.4 84 197 A V T >45S+ 0 0 0 25,-1.9 3,-0.9 -2,-1.3 -1,-0.2 0.898 77.9 56.2 -57.6 -47.1 -49.6 14.3 16.2 85 198 A A T 345S+ 0 0 41 24,-0.5 -79,-0.3 1,-0.3 -1,-0.2 0.872 120.4 32.2 -56.2 -37.0 -52.8 13.3 17.9 86 199 A R T 345S- 0 0 158 -3,-0.3 -1,-0.3 2,-0.1 -2,-0.2 0.436 101.2-134.8 -97.7 -0.8 -51.4 14.6 21.2 87 200 A Q T <<5 + 0 0 60 -3,-0.9 2,-0.3 -4,-0.7 -3,-0.2 0.939 61.3 134.4 42.9 55.6 -49.4 17.4 19.5 88 201 A A E < -D 83 0A 20 -5,-1.7 -5,-2.7 0, 0.0 2,-0.5 -0.947 59.0-111.1-133.7 154.9 -46.5 16.5 21.8 89 202 A D E +D 82 0A 139 -2,-0.3 -7,-0.2 -7,-0.2 2,-0.2 -0.749 37.5 172.5 -93.5 127.1 -42.8 15.9 21.3 90 203 A S E -D 81 0A 39 -9,-3.3 -9,-1.3 -2,-0.5 2,-0.3 -0.484 22.3-127.8-116.0-172.9 -41.3 12.4 21.7 91 204 A K E +D 80 0A 130 -11,-0.2 2,-0.3 -2,-0.2 -11,-0.2 -0.936 31.6 149.1-138.0 157.0 -38.0 10.8 21.1 92 205 A M E -D 79 0A 45 -13,-1.2 -13,-2.5 -2,-0.3 2,-0.4 -0.964 43.5 -93.3-171.3 178.7 -36.9 7.7 19.2 93 206 A T E > -D 78 0A 39 -2,-0.3 4,-2.4 -15,-0.3 5,-0.2 -0.845 33.5-119.8-108.9 146.4 -34.1 6.2 17.2 94 207 A L H > S+ 0 0 0 -17,-2.1 4,-1.6 -2,-0.4 -19,-0.2 0.807 117.8 57.3 -53.6 -24.9 -34.0 6.5 13.4 95 208 A H H > S+ 0 0 97 -20,-2.5 4,-1.7 -18,-0.2 -1,-0.2 0.935 107.3 42.8 -70.4 -49.6 -34.2 2.7 13.6 96 209 A N H > S+ 0 0 60 -21,-0.4 4,-2.0 -3,-0.2 -2,-0.2 0.811 111.5 55.1 -68.9 -31.3 -37.4 2.5 15.5 97 210 A Y H X S+ 0 0 0 -4,-2.4 4,-3.7 2,-0.2 -1,-0.2 0.954 109.1 47.1 -66.7 -48.0 -39.1 5.2 13.5 98 211 A V H X S+ 0 0 3 -4,-1.6 4,-2.5 -5,-0.2 -2,-0.2 0.857 109.9 53.4 -59.2 -39.0 -38.4 3.4 10.2 99 212 A K H X S+ 0 0 135 -4,-1.7 4,-1.2 2,-0.2 -1,-0.2 0.931 114.1 43.1 -61.8 -44.1 -39.7 0.2 11.8 100 213 A Y H < S+ 0 0 25 -4,-2.0 3,-0.4 1,-0.2 -2,-0.2 0.927 112.7 52.8 -64.7 -48.6 -42.8 2.1 12.7 101 214 A F H < S+ 0 0 16 -4,-3.7 -2,-0.2 1,-0.2 -1,-0.2 0.856 112.6 43.8 -58.1 -39.2 -43.0 3.8 9.3 102 215 A M H < S+ 0 0 105 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.679 86.9 99.9 -85.0 -18.4 -42.8 0.5 7.4 103 216 A N S < S- 0 0 79 -4,-1.2 3,-0.2 -3,-0.4 -4,-0.0 -0.507 70.9-142.1 -65.7 131.8 -45.2 -1.5 9.5 104 217 A P S S+ 0 0 128 0, 0.0 2,-0.9 0, 0.0 -1,-0.2 0.790 90.4 64.5 -68.3 -24.2 -48.5 -1.5 7.6 105 218 A N S S- 0 0 67 2,-0.0 -2,-0.1 -3,-0.0 -3,-0.1 -0.670 71.2-171.6-103.3 80.2 -50.5 -1.2 10.9 106 219 A R - 0 0 82 -2,-0.9 -5,-0.0 -3,-0.2 -6,-0.0 -0.589 10.2-166.0 -75.3 112.7 -49.6 2.2 12.4 107 220 A P S S+ 0 0 116 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 0.588 74.7 16.1 -72.3 -12.0 -51.1 2.4 15.9 108 221 A K S S- 0 0 98 2,-0.0 2,-0.7 -23,-0.0 -25,-0.0 -0.984 80.6-107.6-157.3 158.4 -50.4 6.2 16.0 109 222 A V + 0 0 44 -2,-0.3 -25,-1.9 54,-0.1 -24,-0.5 -0.840 42.3 175.5 -96.9 113.3 -49.6 9.1 13.7 110 223 A L E -E 83 0A 22 -2,-0.7 51,-0.9 -27,-0.2 2,-0.4 -0.941 9.9-161.3-120.9 142.0 -46.0 10.2 14.2 111 224 A N E -EF 82 160A 2 -29,-1.7 -29,-2.5 -2,-0.4 2,-0.5 -0.945 11.5-156.9-129.9 144.2 -44.1 12.8 12.3 112 225 A V E + F 0 159A 0 47,-2.2 47,-2.3 -2,-0.4 -31,-0.1 -0.956 33.4 140.3-120.0 113.5 -40.4 13.7 11.6 113 226 A I E + 0 0 44 -2,-0.5 -1,-0.1 -33,-0.3 45,-0.1 0.409 64.0 60.0-130.6 -1.5 -39.7 17.3 10.6 114 227 A S E + 0 0 31 -34,-0.4 2,-1.3 42,-0.1 44,-0.1 0.226 59.9 132.0-115.3 14.5 -36.5 18.3 12.5 115 228 A L E - F 0 157A 5 42,-0.8 42,-2.1 -35,-0.1 2,-0.6 -0.536 35.2-170.6 -74.2 94.4 -33.9 15.7 11.2 116 229 A E E + F 0 156A 29 -2,-1.3 40,-0.2 40,-0.2 3,-0.2 -0.755 12.3 169.6 -87.0 121.5 -30.9 17.8 10.3 117 230 A F > + 0 0 0 38,-1.4 3,-1.8 -2,-0.6 6,-0.3 0.178 38.5 113.3-120.4 17.4 -28.3 15.7 8.5 118 231 A S T 3 S+ 0 0 31 37,-0.5 -1,-0.1 1,-0.3 38,-0.1 0.719 81.8 57.0 -63.9 -15.7 -25.7 18.0 7.1 119 232 A D T 3 S+ 0 0 115 -3,-0.2 -1,-0.3 33,-0.1 2,-0.2 0.004 102.1 73.6-101.1 25.8 -23.3 16.4 9.5 120 233 A T S X S- 0 0 30 -3,-1.8 3,-1.4 1,-0.0 4,-0.4 -0.742 95.4 -95.1-131.8 179.9 -23.9 12.9 8.2 121 234 A K T 3 S+ 0 0 49 -49,-0.8 3,-0.4 1,-0.3 4,-0.3 0.686 118.1 64.7 -69.8 -18.4 -23.1 10.6 5.3 122 235 A M T 3 S+ 0 0 0 -50,-0.5 3,-0.3 1,-0.2 -1,-0.3 0.503 82.9 80.3 -83.8 -1.5 -26.5 11.6 3.7 123 236 A S S X S+ 0 0 21 -3,-1.4 3,-2.2 -6,-0.3 -1,-0.2 0.896 83.9 57.6 -69.6 -42.3 -25.2 15.1 3.3 124 237 A E T 3 S+ 0 0 143 -3,-0.4 -1,-0.2 -4,-0.4 -2,-0.1 0.742 97.3 65.1 -61.5 -23.0 -23.2 14.4 0.2 125 238 A L T 3 S+ 0 0 40 -4,-0.3 2,-0.4 -3,-0.3 -1,-0.3 0.517 102.2 59.1 -78.5 -2.9 -26.4 13.2 -1.4 126 239 A V < + 0 0 4 -3,-2.2 2,-0.4 -67,-0.2 -67,-0.2 -0.982 49.8 179.8-138.6 138.4 -27.9 16.7 -1.2 127 240 A E B -L 58 0B 23 -69,-2.4 -69,-1.8 -2,-0.4 3,-0.1 -0.997 30.0-130.6-130.9 123.0 -27.2 20.3 -2.4 128 241 A V - 0 0 10 -2,-0.4 5,-0.1 -71,-0.2 27,-0.1 -0.248 42.6 -72.0 -70.1 160.1 -29.6 23.1 -1.4 129 242 A P > - 0 0 0 0, 0.0 4,-1.7 0, 0.0 3,-0.3 -0.196 38.0-129.1 -53.6 138.2 -31.1 25.6 -4.0 130 243 A D H > S+ 0 0 80 -75,-3.4 4,-1.8 1,-0.2 5,-0.2 0.872 108.8 58.0 -58.2 -36.5 -28.6 28.1 -5.3 131 244 A I H > S+ 0 0 15 -76,-0.5 4,-2.0 1,-0.2 5,-0.3 0.904 103.9 51.3 -61.8 -40.9 -31.0 30.9 -4.4 132 245 A A H > S+ 0 0 4 -3,-0.3 4,-2.4 1,-0.2 -1,-0.2 0.899 112.8 45.9 -62.8 -40.7 -31.0 29.8 -0.8 133 246 A K H < S+ 0 0 81 -4,-1.7 -1,-0.2 2,-0.2 -2,-0.2 0.753 109.7 55.0 -73.9 -24.4 -27.2 29.8 -0.6 134 247 A K H < S+ 0 0 129 -4,-1.8 -2,-0.2 -5,-0.2 -1,-0.2 0.876 118.1 33.5 -75.1 -38.7 -27.0 33.2 -2.4 135 248 A L H < S+ 0 0 7 -4,-2.0 124,-0.2 -5,-0.2 -2,-0.2 0.846 88.9 116.3 -85.4 -38.0 -29.3 34.9 0.1 136 249 A S X - 0 0 6 -4,-2.4 4,-0.9 -5,-0.3 122,-0.2 -0.007 55.6-150.5 -39.4 123.8 -28.3 33.0 3.3 137 250 A W H > S+ 0 0 2 120,-1.4 4,-3.0 1,-0.2 3,-0.5 0.869 99.3 54.4 -64.4 -40.1 -26.7 35.2 5.9 138 251 A V H > S+ 0 0 5 1,-0.2 4,-0.7 2,-0.2 -1,-0.2 0.864 107.1 52.6 -64.6 -32.8 -24.6 32.2 7.2 139 252 A E H 4 S+ 0 0 97 1,-0.1 -1,-0.2 2,-0.1 -2,-0.2 0.727 122.6 26.6 -73.5 -23.8 -23.3 31.7 3.7 140 253 A N H < S+ 0 0 82 -4,-0.9 -2,-0.2 -3,-0.5 -3,-0.2 0.713 128.2 26.6-114.9 -24.6 -22.2 35.3 3.3 141 254 A Y H < S+ 0 0 49 -4,-3.0 -3,-0.2 -5,-0.1 -2,-0.1 0.354 78.1 113.8-126.2 10.3 -21.3 37.0 6.6 142 255 A W < - 0 0 24 -4,-0.7 8,-0.1 -5,-0.4 147,-0.0 -0.730 62.4-133.4 -89.4 106.8 -20.3 34.3 9.1 143 256 A P > - 0 0 33 0, 0.0 3,-0.9 0, 0.0 -2,-0.1 -0.195 5.4-136.2 -56.1 143.3 -16.5 34.9 9.9 144 257 A D T 3 S+ 0 0 162 1,-0.2 -2,-0.0 6,-0.0 6,-0.0 0.398 102.0 57.2 -81.3 4.5 -14.3 31.8 9.9 145 258 A D T 3 S+ 0 0 98 0, 0.0 -1,-0.2 0, 0.0 2,-0.2 -0.004 76.6 119.0-125.8 28.8 -12.8 33.1 13.1 146 259 A S < - 0 0 34 -3,-0.9 4,-0.1 2,-0.2 -4,-0.0 -0.595 61.2-136.2 -94.9 159.5 -15.7 33.5 15.5 147 260 A V S S+ 0 0 118 -2,-0.2 -1,-0.1 2,-0.1 0, 0.0 0.826 84.6 88.2 -79.0 -32.0 -16.1 31.7 18.8 148 261 A F S S- 0 0 19 1,-0.1 -2,-0.2 193,-0.1 2,-0.2 -0.410 86.1-118.0 -68.1 138.3 -19.8 31.0 18.0 149 262 A P - 0 0 85 0, 0.0 136,-0.2 0, 0.0 -1,-0.1 -0.524 31.1-105.2 -78.7 144.7 -20.3 27.8 16.1 150 263 A K - 0 0 82 -2,-0.2 2,-0.1 -4,-0.1 -6,-0.0 -0.533 40.3-115.0 -71.1 130.3 -21.9 28.1 12.6 151 264 A P - 0 0 15 0, 0.0 2,-0.8 0, 0.0 -1,-0.1 -0.416 16.1-148.6 -69.4 136.4 -25.6 27.0 12.7 152 265 A F + 0 0 125 -2,-0.1 -34,-0.1 1,-0.1 -33,-0.1 -0.838 52.6 123.9-110.1 94.0 -26.7 24.0 10.7 153 266 A V + 0 0 2 -2,-0.8 102,-3.2 102,-0.2 -1,-0.1 -0.073 47.7 91.8-136.4 27.1 -30.2 24.6 9.6 154 267 A Q S S+ 0 0 39 100,-0.2 2,-0.4 1,-0.2 -2,-0.1 0.653 82.4 46.0-100.9 -18.4 -29.7 24.2 5.9 155 268 A K + 0 0 34 99,-0.1 -38,-1.4 97,-0.1 -37,-0.5 -0.887 60.1 161.3-135.4 106.7 -30.5 20.5 5.4 156 269 A Y E -FG 116 253A 17 97,-2.3 97,-1.8 -2,-0.4 2,-0.5 -0.936 23.3-152.1-120.7 142.9 -33.6 18.8 7.0 157 270 A C E -FG 115 252A 0 -42,-2.1 -42,-0.8 -2,-0.4 2,-0.4 -0.970 14.9-159.6-113.8 126.9 -35.1 15.5 6.0 158 271 A L E + G 0 251A 8 93,-3.5 93,-2.1 -2,-0.5 2,-0.4 -0.903 14.5 174.1-111.9 137.4 -38.9 15.2 6.7 159 272 A M E +FG 112 250A 1 -47,-2.3 -47,-2.2 -2,-0.4 2,-0.3 -0.944 11.1 162.6-141.3 115.1 -40.7 11.9 6.9 160 273 A G E -FG 111 249A 0 89,-1.7 89,-2.2 -2,-0.4 2,-0.2 -0.954 30.7-128.5-134.5 154.2 -44.3 11.9 7.9 161 274 A V > - 0 0 3 -51,-0.9 3,-1.4 -2,-0.3 84,-0.2 -0.527 54.4 -66.4 -93.0 166.1 -47.2 9.3 7.7 162 275 A Q T 3 S+ 0 0 103 1,-0.2 84,-0.2 -2,-0.2 -1,-0.2 -0.267 122.7 21.3 -54.0 133.9 -50.6 10.2 6.2 163 276 A D T 3 S+ 0 0 18 82,-3.9 2,-0.3 1,-0.3 -1,-0.2 0.638 78.1 151.1 80.5 18.9 -52.4 12.7 8.4 164 277 A S < - 0 0 1 -3,-1.4 81,-2.6 81,-0.4 2,-0.4 -0.641 27.6-165.0 -77.1 135.4 -49.4 14.2 10.2 165 278 A Y E -H 244 0A 1 -2,-0.3 2,-0.6 79,-0.2 79,-0.2 -0.970 19.1-163.4-134.2 123.7 -50.3 17.7 11.1 166 279 A T E -H 243 0A 28 77,-2.5 77,-1.6 -2,-0.4 3,-0.1 -0.904 29.4-129.2-100.9 122.2 -48.0 20.6 12.2 167 280 A D E - 0 0 16 -2,-0.6 74,-0.1 75,-0.2 44,-0.0 -0.219 42.7 -66.9 -67.8 162.0 -50.1 23.4 13.7 168 281 A F E S+ 0 0 6 74,-0.1 2,-0.3 72,-0.1 74,-0.2 -0.146 71.5 141.6 -50.1 136.3 -49.7 27.0 12.6 169 282 A H E -H 241 0A 43 72,-1.5 72,-2.1 -3,-0.1 2,-0.4 -0.968 48.2-113.6-166.1 170.2 -46.4 28.6 13.4 170 283 A I - 0 0 6 -2,-0.3 70,-0.1 70,-0.2 3,-0.1 -0.945 47.1 -99.9-113.8 135.0 -43.7 31.0 12.1 171 284 A D > - 0 0 25 68,-0.4 3,-2.3 -2,-0.4 4,-0.3 -0.220 53.4 -80.6 -58.1 144.1 -40.3 29.5 11.4 172 285 A F G > S+ 0 0 7 1,-0.3 3,-1.8 2,-0.2 -1,-0.1 -0.060 112.6 4.1 -47.3 137.8 -37.6 30.0 14.0 173 286 A G G 3 S- 0 0 2 1,-0.3 96,-0.3 95,-0.2 -1,-0.3 0.497 122.2 -77.5 64.1 4.9 -35.9 33.4 14.0 174 287 A G G < S+ 0 0 0 -3,-2.3 -1,-0.3 94,-0.2 -2,-0.2 0.755 82.6 167.8 76.9 24.8 -38.2 34.6 11.2 175 288 A T < - 0 0 3 -3,-1.8 -4,-0.3 -4,-0.3 63,-0.2 -0.279 34.9-124.0 -72.2 156.7 -36.2 32.6 8.7 176 289 A S E -I 256 0A 0 80,-2.5 80,-2.0 61,-0.1 2,-0.3 -0.522 32.0-155.0 -90.0 166.7 -37.4 31.9 5.1 177 290 A V E -IJ 255 235A 13 58,-2.3 58,-2.1 78,-0.2 2,-0.4 -0.992 16.4-148.5-148.9 151.3 -37.5 28.3 4.0 178 291 A W E -IJ 254 234A 4 76,-1.8 76,-1.5 -2,-0.3 2,-0.4 -0.927 18.6-168.5-116.9 148.5 -37.4 26.1 0.9 179 292 A Y E -IJ 253 233A 18 54,-2.2 54,-2.9 -2,-0.4 2,-0.4 -0.987 7.4-176.2-143.7 127.7 -39.3 22.9 0.7 180 293 A H E -IJ 252 232A 6 72,-3.0 72,-2.5 -2,-0.4 2,-0.7 -0.985 17.2-144.7-128.8 129.9 -39.1 20.0 -1.8 181 294 A V E -I 251 0A 0 50,-1.8 49,-2.7 -2,-0.4 70,-0.3 -0.814 11.7-175.2 -94.7 115.2 -41.3 16.9 -1.9 182 295 A L E S- 0 0 4 68,-1.9 2,-0.3 -2,-0.7 -1,-0.2 0.950 73.7 -22.0 -71.2 -50.3 -39.4 13.8 -3.0 183 296 A W E S+I 250 0A 50 67,-1.4 67,-1.9 46,-0.1 -1,-0.3 -0.958 113.4 35.8-152.3 164.1 -42.5 11.6 -3.0 184 297 A G E S- 0 0 16 -2,-0.3 45,-0.6 65,-0.2 2,-0.3 -0.611 84.9 -83.6 88.7-150.6 -45.9 11.7 -1.3 185 298 A E E -IK 247 228A 31 62,-1.2 62,-1.2 -2,-0.2 61,-0.9 -0.925 26.7-163.0-165.5 137.3 -47.7 15.0 -0.7 186 299 A K E -IK 245 227A 2 41,-2.0 41,-2.8 -2,-0.3 2,-0.5 -0.912 10.4-152.9-118.6 146.2 -47.8 17.9 1.7 187 300 A I E -IK 244 226A 13 57,-2.5 57,-2.1 -2,-0.3 2,-0.3 -0.957 12.8-157.3-123.3 111.9 -50.6 20.5 2.0 188 301 A F E -IK 243 225A 6 37,-3.1 37,-3.4 -2,-0.5 2,-0.6 -0.686 7.9-153.8 -91.0 140.2 -49.6 24.0 3.4 189 302 A Y E -IK 242 224A 2 53,-3.0 53,-1.5 -2,-0.3 2,-0.5 -0.949 23.4-162.3-113.0 108.3 -52.0 26.4 5.0 190 303 A L E -IK 241 223A 0 33,-2.9 33,-2.1 -2,-0.6 2,-0.4 -0.832 14.5-174.5-104.8 127.9 -50.5 29.9 4.4 191 304 A I E -I 240 0A 0 49,-3.4 49,-1.9 -2,-0.5 31,-0.1 -0.962 27.6-121.6-120.2 129.3 -51.4 33.1 6.3 192 305 A K - 0 0 117 -2,-0.4 2,-2.2 29,-0.4 5,-0.2 -0.443 23.8-120.6 -69.1 137.9 -50.0 36.5 5.3 193 306 A P + 0 0 15 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.294 51.0 159.6 -77.8 57.3 -48.0 38.3 8.0 194 307 A T > - 0 0 45 -2,-2.2 4,-2.6 1,-0.1 5,-0.3 -0.458 57.4-108.5 -73.7 153.3 -50.2 41.4 8.1 195 308 A D H > S+ 0 0 112 1,-0.2 4,-1.9 2,-0.2 5,-0.2 0.843 123.3 52.0 -51.6 -34.0 -49.9 43.4 11.3 196 309 A E H > S+ 0 0 84 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.936 111.2 45.6 -67.3 -47.8 -53.4 42.1 12.2 197 310 A N H > S+ 0 0 10 1,-0.2 4,-1.8 2,-0.2 -2,-0.2 0.816 111.7 51.6 -67.3 -32.3 -52.5 38.5 11.6 198 311 A L H X S+ 0 0 6 -4,-2.6 4,-2.3 2,-0.2 5,-0.2 0.936 110.5 47.5 -71.2 -44.9 -49.2 38.7 13.5 199 312 A A H X S+ 0 0 56 -4,-1.9 4,-1.5 -5,-0.3 -2,-0.2 0.939 114.2 47.8 -59.4 -47.8 -50.9 40.2 16.6 200 313 A R H X S+ 0 0 98 -4,-2.1 4,-2.5 1,-0.2 -1,-0.2 0.854 110.0 52.3 -62.3 -37.8 -53.6 37.6 16.5 201 314 A Y H X S+ 0 0 21 -4,-1.8 4,-2.1 2,-0.2 -1,-0.2 0.926 109.4 48.2 -65.6 -44.5 -51.1 34.8 16.1 202 315 A E H X S+ 0 0 42 -4,-2.3 4,-1.1 1,-0.2 -1,-0.2 0.785 113.0 50.6 -65.7 -26.9 -49.1 35.9 19.1 203 316 A S H < S+ 0 0 76 -4,-1.5 -2,-0.2 -5,-0.2 -1,-0.2 0.900 110.3 47.6 -74.8 -44.7 -52.4 36.1 21.0 204 317 A W H >< S+ 0 0 12 -4,-2.5 3,-0.8 1,-0.2 -2,-0.2 0.794 110.1 54.7 -66.1 -31.7 -53.4 32.6 19.9 205 318 A S H 3< S+ 0 0 31 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.828 108.2 47.8 -72.8 -34.5 -50.0 31.2 20.9 206 319 A S T 3< S+ 0 0 85 -4,-1.1 2,-0.4 -5,-0.2 -1,-0.2 -0.150 94.9 94.3-100.7 37.2 -50.2 32.6 24.4 207 320 A S S X S- 0 0 43 -3,-0.8 3,-1.5 1,-0.1 -4,-0.0 -0.987 73.7-133.4-129.4 139.3 -53.7 31.3 25.1 208 321 A V G > S+ 0 0 142 -2,-0.4 3,-0.6 1,-0.3 -1,-0.1 0.869 104.1 58.2 -58.0 -39.6 -54.5 28.0 26.8 209 322 A T G >> + 0 0 59 1,-0.2 3,-2.4 2,-0.1 4,-0.7 0.314 68.7 117.8 -76.9 10.4 -57.2 27.1 24.2 210 323 A Q G X4 S+ 0 0 64 -3,-1.5 3,-0.8 1,-0.3 -1,-0.2 0.830 73.3 52.1 -45.0 -41.1 -54.6 27.2 21.4 211 324 A S G <4 S+ 0 0 42 -3,-0.6 -207,-1.9 1,-0.2 -1,-0.3 0.551 110.5 46.5 -78.4 -6.7 -55.1 23.5 20.6 212 325 A E G <4 S+ 0 0 87 -3,-2.4 2,-0.5 -209,-0.2 -210,-0.4 0.352 101.3 76.6-112.2 2.0 -58.9 23.7 20.3 213 326 A V S << S- 0 0 38 -3,-0.8 2,-0.7 -4,-0.7 -1,-0.1 -0.947 74.5-141.7-120.1 111.0 -58.9 26.8 18.2 214 327 A F > - 0 0 15 -2,-0.5 3,-2.1 1,-0.2 4,-0.2 -0.594 10.4-151.4 -71.8 111.4 -58.1 26.5 14.5 215 328 A F G > S+ 0 0 0 -2,-0.7 3,-1.8 1,-0.3 4,-0.2 0.721 89.6 73.0 -58.4 -22.8 -56.0 29.6 13.7 216 329 A G G > S+ 0 0 8 1,-0.3 3,-0.8 2,-0.2 -1,-0.3 0.809 92.0 58.3 -61.4 -27.5 -57.2 29.6 10.1 217 330 A D G < S+ 0 0 101 -3,-2.1 -1,-0.3 1,-0.2 -2,-0.2 0.456 95.9 63.6 -80.7 -2.2 -60.6 30.8 11.4 218 331 A K G < S+ 0 0 113 -3,-1.8 2,-0.3 -4,-0.2 -1,-0.2 0.409 98.4 57.0-103.8 1.7 -59.1 33.9 13.0 219 332 A V S < S- 0 0 15 -3,-0.8 3,-0.1 -4,-0.2 -28,-0.0 -0.823 86.0-110.3-128.0 168.0 -57.9 35.6 9.9 220 333 A D S S+ 0 0 128 -2,-0.3 2,-0.4 1,-0.2 -1,-0.1 0.935 98.0 16.5 -63.1 -49.9 -59.4 36.8 6.6 221 334 A K - 0 0 89 -29,-0.1 2,-0.5 -203,-0.0 -29,-0.4 -0.990 50.6-173.4-137.6 135.6 -57.8 34.3 4.4 222 335 A C - 0 0 7 -2,-0.4 2,-0.3 -3,-0.1 -31,-0.2 -0.900 26.7-147.0-123.5 95.9 -56.0 30.9 4.9 223 336 A Y E - K 0 190A 31 -33,-2.1 -33,-2.9 -2,-0.5 2,-0.6 -0.498 2.5-142.8 -73.0 123.9 -54.5 29.8 1.5 224 337 A K E -aK 20 189A 67 -205,-2.3 -203,-2.1 -2,-0.3 2,-0.5 -0.737 19.8-174.2 -86.2 120.7 -54.4 26.1 0.8 225 338 A C E - K 0 188A 4 -37,-3.4 -37,-3.1 -2,-0.6 2,-0.7 -0.953 11.1-153.7-121.5 115.1 -51.2 25.2 -1.1 226 339 A V E - K 0 187A 51 -2,-0.5 2,-0.8 -39,-0.2 -39,-0.2 -0.759 4.5-163.3 -90.8 114.5 -50.8 21.7 -2.4 227 340 A V E - K 0 186A 0 -41,-2.8 -41,-2.0 -2,-0.7 2,-0.1 -0.849 14.6-172.6 -99.0 106.9 -47.2 20.7 -2.8 228 341 A K E > - K 0 185A 115 -2,-0.8 3,-1.7 -43,-0.2 -47,-0.4 -0.443 39.2 -63.3 -91.3 170.7 -47.1 17.6 -5.0 229 342 A Q T 3 S+ 0 0 99 -45,-0.6 -47,-0.2 1,-0.2 -1,-0.2 -0.153 121.0 22.0 -53.7 143.1 -44.0 15.4 -5.7 230 343 A G T 3 S+ 0 0 23 -49,-2.7 2,-0.2 1,-0.3 -1,-0.2 0.337 98.0 122.1 80.8 -7.3 -41.2 17.0 -7.6 231 344 A H < - 0 0 51 -3,-1.7 -50,-1.8 -50,-0.2 2,-0.5 -0.625 48.4-154.0 -93.1 149.1 -42.3 20.5 -6.5 232 345 A T E -CJ 49 180A 0 -183,-2.2 -183,-2.8 -2,-0.2 2,-0.4 -0.982 7.5-166.0-124.4 124.0 -40.3 23.1 -4.6 233 346 A L E -CJ 48 179A 0 -54,-2.9 -54,-2.2 -2,-0.5 2,-0.6 -0.912 5.5-159.5-110.9 134.8 -42.0 25.8 -2.4 234 347 A F E -CJ 47 178A 2 -187,-2.7 -187,-1.9 -2,-0.4 -56,-0.2 -0.929 9.3-163.7-115.4 107.5 -40.2 28.9 -1.1 235 348 A V E - J 0 177A 2 -58,-2.1 -58,-2.3 -2,-0.6 3,-0.1 -0.801 13.0-141.5 -95.5 122.8 -41.9 30.4 1.9 236 349 A P > - 0 0 3 0, 0.0 3,-1.3 0, 0.0 -192,-0.1 -0.075 37.4 -55.6 -75.4 176.0 -40.8 34.0 2.8 237 350 A T T 3 S+ 0 0 5 -194,-0.4 -62,-0.1 1,-0.2 -61,-0.1 -0.115 113.8 3.9 -53.8 141.6 -40.3 35.7 6.2 238 351 A G T 3 S+ 0 0 1 -63,-0.2 2,-0.3 1,-0.2 -1,-0.2 0.403 81.6 150.8 65.5 -0.9 -43.0 35.8 8.8 239 352 A W < - 0 0 8 -3,-1.3 -68,-0.4 -65,-0.1 2,-0.4 -0.490 40.8-139.0 -69.5 125.1 -45.5 33.7 6.9 240 353 A I E + I 0 191A 0 -49,-1.9 -49,-3.4 -2,-0.3 2,-0.3 -0.685 35.7 164.4 -82.0 131.8 -47.8 31.8 9.3 241 354 A H E -HI 169 190A 8 -72,-2.1 -72,-1.5 -2,-0.4 2,-0.3 -1.000 31.8-161.7-154.5 155.0 -48.4 28.3 8.2 242 355 A A E - I 0 189A 0 -53,-1.5 -53,-3.0 -2,-0.3 2,-0.4 -0.907 20.2-148.2-127.0 154.2 -49.6 24.8 9.1 243 356 A V E -HI 166 188A 11 -77,-1.6 -77,-2.5 -2,-0.3 2,-0.4 -0.987 7.4-164.1-132.7 139.0 -48.8 21.6 7.1 244 357 A L E -HI 165 187A 0 -57,-2.1 -57,-2.5 -2,-0.4 2,-1.2 -0.982 18.5-139.5-122.7 129.7 -50.8 18.4 6.5 245 358 A T E - I 0 186A 2 -81,-2.6 -82,-3.9 -2,-0.4 -81,-0.4 -0.755 19.4-175.7 -87.8 97.0 -49.2 15.2 5.2 246 359 A S E S+ 0 0 7 -2,-1.2 2,-0.3 -61,-0.9 -1,-0.2 0.731 71.4 3.6 -66.0 -23.0 -52.0 14.1 2.9 247 360 A Q E S- I 0 185A 88 -62,-1.2 -62,-1.2 -86,-0.1 -1,-0.2 -0.978 105.5 -60.4-161.3 152.0 -50.1 11.0 2.2 248 361 A D E S- 0 0 46 -2,-0.3 2,-0.3 -64,-0.2 -87,-0.2 -0.034 71.4-179.3 -34.7 117.3 -46.9 9.2 3.3 249 362 A C E -G 160 0A 0 -89,-2.2 -89,-1.7 -65,-0.2 2,-0.4 -0.901 35.2-165.6-135.0 156.2 -44.2 11.6 2.4 250 363 A M E +GI 159 183A 0 -67,-1.9 -68,-1.9 -2,-0.3 -67,-1.4 -0.993 27.2 162.1-134.8 129.2 -40.5 12.3 2.3 251 364 A A E -GI 158 181A 0 -93,-2.1 -93,-3.5 -2,-0.4 2,-0.3 -0.924 25.9-140.7-143.0 166.4 -39.4 15.9 1.7 252 365 A F E +GI 157 180A 2 -72,-2.5 -72,-3.0 -2,-0.3 2,-0.3 -0.931 27.9 152.6-128.8 152.9 -36.3 18.0 2.2 253 366 A G E -GI 156 179A 3 -97,-1.8 -97,-2.3 -2,-0.3 2,-0.3 -0.947 19.1-158.6-162.5-176.6 -35.9 21.6 3.3 254 367 A G E - I 0 178A 1 -76,-1.5 -76,-1.8 -2,-0.3 2,-0.3 -0.976 15.9-124.4-169.7 160.5 -33.8 24.3 4.9 255 368 A N E + I 0 177A 11 -102,-3.2 2,-0.3 -2,-0.3 -78,-0.2 -0.854 25.8 175.0-116.2 150.3 -34.0 27.7 6.6 256 369 A F E - I 0 176A 8 -80,-2.0 -80,-2.5 -2,-0.3 2,-0.3 -0.971 22.0-143.6-158.4 139.9 -32.2 31.0 5.7 257 370 A L + 0 0 3 -2,-0.3 -120,-1.4 -82,-0.2 2,-0.3 -0.691 29.3 176.3 -96.8 153.0 -31.9 34.6 6.8 258 371 A H - 0 0 0 -2,-0.3 3,-0.2 -122,-0.2 7,-0.1 -0.924 42.4-106.4-150.5 175.2 -31.4 37.3 4.2 259 372 A N S S+ 0 0 25 -2,-0.3 3,-0.5 -124,-0.2 59,-0.1 0.493 98.4 78.2 -84.9 -4.7 -31.1 41.1 3.6 260 373 A L S S+ 0 0 18 1,-0.2 -1,-0.2 2,-0.1 3,-0.2 0.907 106.0 20.4 -75.0 -42.0 -34.5 41.5 1.9 261 374 A N > + 0 0 28 -3,-0.2 4,-2.0 1,-0.1 -1,-0.2 -0.376 69.1 146.2-125.0 56.0 -36.9 41.5 4.9 262 375 A I H > S+ 0 0 1 -3,-0.5 4,-2.2 52,-0.2 5,-0.2 0.832 72.5 59.7 -60.3 -32.6 -34.7 42.4 7.9 263 376 A G H > S+ 0 0 32 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.978 108.4 41.9 -59.5 -55.4 -37.7 44.2 9.5 264 377 A M H > S+ 0 0 36 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.838 111.6 56.5 -60.6 -36.0 -39.9 41.2 9.6 265 378 A Q H X S+ 0 0 0 -4,-2.0 4,-1.4 1,-0.2 -1,-0.2 0.912 109.7 45.3 -64.7 -39.7 -37.0 39.0 10.7 266 379 A L H X S+ 0 0 7 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.849 111.8 52.4 -71.5 -34.5 -36.4 41.2 13.7 267 380 A R H X S+ 0 0 105 -4,-2.0 4,-1.6 1,-0.2 -2,-0.2 0.905 110.4 47.7 -66.8 -43.1 -40.1 41.4 14.5 268 381 A C H X S+ 0 0 3 -4,-2.4 4,-1.9 2,-0.2 -94,-0.2 0.812 111.2 50.8 -68.6 -31.2 -40.4 37.6 14.5 269 382 A Y H X S+ 0 0 25 -4,-1.4 4,-0.8 -96,-0.3 -2,-0.2 0.931 110.4 48.3 -71.6 -45.6 -37.4 37.1 16.7 270 383 A E H X S+ 0 0 56 -4,-2.0 4,-1.6 1,-0.2 3,-0.2 0.819 111.7 50.9 -64.5 -30.1 -38.6 39.5 19.3 271 384 A M H X S+ 0 0 13 -4,-1.6 4,-1.8 1,-0.2 5,-0.2 0.926 105.5 55.4 -71.4 -44.4 -42.0 37.9 19.3 272 385 A E H <>S+ 0 0 12 -4,-1.9 5,-2.5 1,-0.2 -1,-0.2 0.635 107.1 51.0 -63.2 -15.3 -40.4 34.4 19.8 273 386 A K H ><5S+ 0 0 78 -4,-0.8 3,-0.9 -3,-0.2 -1,-0.2 0.871 107.2 52.4 -85.9 -43.2 -38.7 35.8 22.9 274 387 A R H 3<5S+ 0 0 136 -4,-1.6 -2,-0.2 1,-0.3 -3,-0.1 0.793 118.1 37.6 -60.3 -30.8 -41.9 37.1 24.3 275 388 A L T 3<5S- 0 0 43 -4,-1.8 -1,-0.3 -5,-0.1 -2,-0.2 0.426 106.5-131.2 -99.9 -1.7 -43.5 33.7 23.8 276 389 A K T < 5 - 0 0 177 -3,-0.9 -3,-0.2 -5,-0.2 -4,-0.1 0.953 29.8-159.5 48.5 63.0 -40.3 31.9 24.8 277 390 A T > < - 0 0 29 -5,-2.5 3,-1.6 1,-0.1 4,-0.2 -0.618 20.0-146.6 -80.1 121.4 -40.3 29.6 21.8 278 391 A P G > S+ 0 0 113 0, 0.0 3,-1.2 0, 0.0 -1,-0.1 0.680 95.2 73.6 -57.2 -18.5 -38.2 26.3 22.2 279 392 A D G > S+ 0 0 66 1,-0.3 3,-2.7 2,-0.2 4,-0.2 0.862 76.6 73.2 -64.9 -38.4 -37.6 26.7 18.4 280 393 A L G X S+ 0 0 34 -3,-1.6 3,-1.2 1,-0.3 -1,-0.3 0.620 77.4 80.7 -53.3 -12.4 -35.2 29.6 18.9 281 394 A F G < S+ 0 0 78 -3,-1.2 -1,-0.3 1,-0.2 -2,-0.2 0.571 82.8 64.2 -71.7 -7.8 -32.8 26.9 20.2 282 395 A K G < S+ 0 0 66 -3,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.637 109.4 35.3 -89.3 -18.7 -32.0 26.2 16.6 283 396 A F S X S+ 0 0 9 -3,-1.2 3,-1.3 -4,-0.2 -1,-0.2 -0.492 72.6 164.7-130.6 60.5 -30.5 29.6 15.9 284 397 A P T 3 S+ 0 0 68 0, 0.0 3,-0.3 0, 0.0 -1,-0.1 0.793 75.8 44.3 -47.7 -35.3 -28.8 30.2 19.3 285 398 A F T 3> + 0 0 44 1,-0.2 4,-1.8 -136,-0.2 5,-0.2 -0.312 65.8 132.3-113.3 50.7 -26.7 33.1 17.9 286 399 A F H <> S+ 0 0 1 -3,-1.3 4,-1.3 1,-0.2 -1,-0.2 0.829 78.6 50.5 -65.7 -34.0 -29.2 35.0 15.9 287 400 A E H > S+ 0 0 4 -3,-0.3 4,-1.4 2,-0.2 -1,-0.2 0.880 104.1 57.9 -73.4 -37.0 -28.0 38.2 17.5 288 401 A A H >> S+ 0 0 0 1,-0.2 4,-1.7 2,-0.2 3,-0.7 0.945 108.4 45.3 -57.4 -50.8 -24.4 37.4 16.7 289 402 A I H 3X S+ 0 0 0 -4,-1.8 4,-2.6 1,-0.2 -1,-0.2 0.862 105.8 62.1 -63.9 -33.2 -25.1 37.2 13.0 290 403 A C H 3X S+ 0 0 0 -4,-1.3 4,-1.8 1,-0.2 -1,-0.2 0.821 104.3 48.3 -60.7 -32.8 -27.1 40.4 13.2 291 404 A W H <>S+ 0 0 52 -4,-2.4 5,-3.3 1,-0.2 3,-0.8 0.842 115.2 51.7 -48.1 -34.7 -22.8 54.4 -1.8 305 418 A R H ><5S+ 0 0 58 -4,-2.9 3,-2.2 1,-0.2 -1,-0.2 0.971 104.7 51.4 -68.9 -54.7 -22.9 57.6 0.3 306 419 A E T 3<5S+ 0 0 158 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.288 114.0 47.2 -69.4 15.1 -19.3 58.7 -0.3 307 420 A D T < 5S- 0 0 117 -3,-0.8 -1,-0.3 -4,-0.3 -2,-0.2 0.169 119.1-104.1-137.4 13.2 -19.9 58.4 -4.0 308 421 A G T < 5S+ 0 0 71 -3,-2.2 2,-0.3 1,-0.2 -3,-0.2 0.769 72.7 134.7 69.4 31.9 -23.2 60.2 -4.2 309 422 A F < - 0 0 118 -5,-3.3 -1,-0.2 -6,-0.2 -2,-0.2 -0.794 48.9-133.3-111.8 155.4 -25.6 57.3 -4.6 310 423 A Q - 0 0 103 -2,-0.3 3,-0.1 1,-0.0 56,-0.0 -0.876 27.8-121.1-105.3 136.4 -28.9 56.6 -2.9 311 424 A P - 0 0 16 0, 0.0 2,-0.1 0, 0.0 5,-0.1 -0.278 32.9 -91.5 -73.2 160.8 -29.5 53.0 -1.5 312 425 A Q >> - 0 0 97 1,-0.1 4,-1.2 4,-0.0 3,-0.9 -0.385 40.5-112.0 -68.2 151.7 -32.4 50.8 -2.6 313 426 A T H >> S+ 0 0 99 1,-0.3 4,-2.3 2,-0.2 3,-0.7 0.900 114.3 52.7 -53.0 -50.2 -35.5 51.1 -0.4 314 427 A Y H 3> S+ 0 0 44 1,-0.2 4,-2.3 -275,-0.2 -1,-0.3 0.784 106.6 56.2 -60.0 -26.1 -35.3 47.7 1.2 315 428 A L H <> S+ 0 0 14 -3,-0.9 4,-2.0 2,-0.2 -1,-0.2 0.818 108.1 44.6 -77.4 -30.5 -31.8 48.4 2.3 316 429 A V H < S+ 0 0 65 -4,-2.1 3,-1.0 1,-0.2 -2,-0.2 0.883 106.1 54.7 -69.1 -39.2 -32.4 48.0 22.2 329 442 A W H 3< S+ 0 0 2 -4,-2.3 9,-0.3 1,-0.2 -1,-0.2 0.696 105.6 55.0 -68.7 -17.1 -30.1 45.1 23.0 330 443 A M T 3< S+ 0 0 53 -4,-0.7 -1,-0.2 -3,-0.4 -2,-0.2 0.536 72.5 130.7 -94.0 -8.0 -27.6 47.5 24.5 331 444 A K X> - 0 0 107 -3,-1.0 3,-3.2 -4,-0.4 4,-3.0 -0.213 69.2-119.9 -49.4 131.7 -29.9 49.2 27.0 332 445 A K T 34 S+ 0 0 82 1,-0.3 4,-0.4 2,-0.2 -1,-0.1 0.849 113.7 51.2 -40.0 -48.5 -28.2 49.3 30.4 333 446 A E T 34 S+ 0 0 124 1,-0.2 -1,-0.3 2,-0.1 -2,-0.1 0.257 122.6 30.0 -78.6 12.6 -31.0 47.3 31.9 334 447 A L T X> S+ 0 0 53 -3,-3.2 3,-2.4 -4,-0.1 4,-0.7 0.531 89.1 90.5-139.2 -27.5 -30.8 44.6 29.2 335 448 A V H 3X S+ 0 0 41 -4,-3.0 4,-2.3 1,-0.3 3,-0.2 0.670 76.0 74.1 -51.4 -19.8 -27.3 44.4 27.9 336 449 A S H 34 S+ 0 0 108 -4,-0.4 -1,-0.3 1,-0.2 4,-0.2 0.704 102.2 39.7 -69.8 -18.7 -26.5 41.7 30.6 337 450 A E H <4 S+ 0 0 99 -3,-2.4 -1,-0.2 -8,-0.2 -2,-0.2 0.576 121.7 41.4-103.6 -13.9 -28.4 39.1 28.6 338 451 A H H >< S+ 0 0 6 -4,-0.7 3,-1.9 -9,-0.3 4,-0.5 0.649 90.8 89.1-104.4 -22.1 -27.3 40.2 25.1 339 452 A A G >< S+ 0 0 46 -4,-2.3 3,-2.0 1,-0.3 -3,-0.1 0.845 81.3 55.6 -43.7 -53.2 -23.6 40.8 25.9 340 453 A F G 3 S+ 0 0 131 1,-0.3 -1,-0.3 -4,-0.2 -2,-0.1 0.672 102.8 59.0 -61.0 -15.9 -22.3 37.3 25.3 341 454 A E G < S+ 0 0 6 -3,-1.9 -1,-0.3 2,-0.1 -2,-0.2 0.584 79.4 102.2 -89.3 -11.0 -23.7 37.5 21.8 342 455 A I S < S- 0 0 29 -3,-2.0 -54,-0.1 -4,-0.5 -55,-0.0 -0.627 78.2-123.1 -74.5 121.5 -21.7 40.6 20.8 343 456 A P > - 0 0 5 0, 0.0 3,-1.1 0, 0.0 -1,-0.1 -0.207 9.6-125.3 -62.5 154.6 -18.8 39.4 18.6 344 457 A D T 3 S+ 0 0 153 1,-0.2 -2,-0.0 3,-0.1 -198,-0.0 0.658 108.5 62.0 -78.2 -9.6 -15.3 40.2 19.7 345 458 A N T 3 S+ 0 0 86 2,-0.0 2,-0.4 0, 0.0 -1,-0.2 0.379 93.5 79.1 -92.5 2.7 -14.7 41.9 16.3 346 459 A V < - 0 0 10 -3,-1.1 -54,-0.1 4,-0.0 -55,-0.0 -0.914 66.2-146.8-119.4 142.1 -17.4 44.5 16.7 347 460 A R > - 0 0 160 -2,-0.4 4,-3.1 1,-0.2 3,-0.3 -0.800 19.3-166.4-103.2 90.4 -17.4 47.7 18.7 348 461 A P H > S+ 0 0 35 0, 0.0 4,-2.2 0, 0.0 5,-0.2 0.872 83.0 44.4 -39.6 -64.3 -21.1 47.9 19.8 349 462 A G H 4 S+ 0 0 54 1,-0.2 4,-0.5 2,-0.2 -2,-0.0 0.877 118.3 45.2 -54.4 -42.3 -21.2 51.5 20.9 350 463 A H H >> S+ 0 0 82 -3,-0.3 4,-2.4 2,-0.2 3,-1.1 0.936 110.5 51.1 -68.6 -51.1 -19.4 52.7 17.8 351 464 A L H 3X S+ 0 0 7 -4,-3.1 4,-2.7 1,-0.3 5,-0.3 0.924 107.2 53.4 -53.8 -49.5 -21.3 50.7 15.2 352 465 A I H 3X S+ 0 0 21 -4,-2.2 4,-1.3 -5,-0.3 -1,-0.3 0.738 111.1 49.7 -59.9 -21.3 -24.6 51.9 16.5 353 466 A K H <> S+ 0 0 44 -3,-1.1 4,-2.2 -4,-0.5 5,-0.3 0.898 108.2 49.0 -82.9 -46.0 -23.2 55.4 16.1 354 467 A E H X S+ 0 0 22 -4,-2.4 4,-2.3 1,-0.2 -2,-0.2 0.882 114.3 48.4 -60.2 -38.5 -22.0 54.9 12.5 355 468 A L H X S+ 0 0 2 -4,-2.7 4,-2.4 -5,-0.2 5,-0.3 0.929 106.9 57.4 -66.0 -46.1 -25.4 53.5 11.7 356 469 A S H X S+ 0 0 42 -4,-1.3 4,-2.1 -5,-0.3 -2,-0.2 0.909 113.8 36.2 -50.9 -52.3 -27.1 56.4 13.4 357 470 A K H X S+ 0 0 108 -4,-2.2 4,-3.7 2,-0.2 -1,-0.2 0.918 112.8 56.6 -72.5 -43.8 -25.4 59.1 11.3 358 471 A V H X S+ 0 0 16 -4,-2.3 4,-1.5 -5,-0.3 -1,-0.2 0.881 114.3 42.3 -55.3 -35.8 -25.4 57.1 8.0 359 472 A I H X S+ 0 0 23 -4,-2.4 4,-2.6 -5,-0.2 -1,-0.2 0.892 111.4 55.6 -76.1 -39.2 -29.2 56.8 8.5 360 473 A R H X S+ 0 0 56 -4,-2.1 4,-2.6 -5,-0.3 5,-0.2 0.943 109.4 47.6 -56.2 -50.3 -29.3 60.5 9.6 361 474 A A H >X S+ 0 0 50 -4,-3.7 4,-3.2 2,-0.2 3,-1.0 0.981 112.2 46.0 -52.6 -77.3 -27.6 61.5 6.3 362 475 A I H 3< S+ 0 0 26 -4,-1.5 -1,-0.2 1,-0.3 -2,-0.2 0.798 114.2 50.4 -33.9 -48.7 -29.8 59.4 3.9 363 476 A E H 3< S+ 0 0 59 -4,-2.6 3,-0.5 1,-0.1 -1,-0.3 0.933 121.8 32.5 -60.2 -47.4 -32.9 60.6 5.8 364 477 A E H << S+ 0 0 81 -4,-2.6 2,-2.3 -3,-1.0 -2,-0.2 0.956 110.9 61.1 -74.4 -53.8 -31.8 64.3 5.5 365 478 A E < 0 0 75 -4,-3.2 -1,-0.2 -5,-0.2 -3,-0.1 0.037 360.0 360.0 -65.9 34.2 -30.0 64.1 2.1 366 479 A N 0 0 144 -2,-2.3 0, 0.0 -3,-0.5 0, 0.0 -0.929 360.0 360.0-172.6 360.0 -33.5 63.1 0.9