==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=29-APR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 01-DEC-09 3KW8 . COMPND 2 MOLECULE: PUTATIVE COPPER OXIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES COELICOLOR; . AUTHOR T.SKALOVA,J.DOHNALEK,P.KOLENKO,J.DUSKOVA,A.STEPANKOVA,J.HASE . 273 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13267.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 171 62.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 28 10.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 62 22.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 32 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 24 8.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 8 2.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 4 1 2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 45 A G 0 0 98 0, 0.0 39,-0.1 0, 0.0 2,-0.1 0.000 360.0 360.0 360.0 -69.2 -18.6 18.4 -7.2 2 46 A G - 0 0 44 36,-0.1 2,-0.3 37,-0.1 39,-0.1 0.714 360.0-154.9-107.4-178.5 -21.1 17.2 -8.1 3 47 A E - 0 0 117 35,-0.2 39,-2.6 -2,-0.1 2,-0.6 -0.738 14.9-135.4-107.4 145.6 -23.3 18.5 -10.9 4 48 A V E -a 42 0A 91 -2,-0.3 2,-0.3 37,-0.2 39,-0.2 -0.896 33.8-174.2 -92.5 120.0 -27.0 18.2 -11.7 5 49 A R E -a 43 0A 80 37,-2.8 39,-2.6 -2,-0.6 2,-0.4 -0.890 13.2-154.2-119.7 152.3 -27.3 17.4 -15.4 6 50 A H E +a 44 0A 145 -2,-0.3 2,-0.3 37,-0.2 39,-0.2 -0.947 17.4 169.5-125.7 144.9 -30.4 17.0 -17.7 7 51 A L E -a 45 0A 38 37,-2.1 39,-3.0 -2,-0.4 2,-0.4 -0.994 25.1-135.6-156.4 148.3 -30.7 15.0 -20.8 8 52 A K E +a 46 0A 113 -2,-0.3 2,-0.3 37,-0.2 39,-0.2 -0.888 23.9 176.9-105.4 142.8 -33.3 13.8 -23.3 9 53 A M E -a 47 0A 0 37,-2.0 39,-2.4 -2,-0.4 2,-0.3 -0.982 8.9-162.3-141.5 152.7 -33.4 10.3 -24.7 10 54 A Y E -aB 48 22A 30 12,-2.4 12,-2.0 -2,-0.3 2,-0.5 -0.937 11.4-146.9-130.6 148.2 -35.7 8.5 -27.0 11 55 A A E +aB 49 21A 0 37,-1.9 39,-2.1 -2,-0.3 2,-0.3 -0.976 31.3 173.1-108.1 137.0 -36.4 4.9 -27.8 12 56 A E E - B 0 20A 29 8,-2.7 8,-2.8 -2,-0.5 2,-0.3 -0.994 33.9-120.1-146.7 151.9 -37.4 4.2 -31.4 13 57 A K E - B 0 19A 96 -2,-0.3 2,-0.3 6,-0.2 6,-0.3 -0.694 31.5-140.0 -85.5 140.2 -38.1 1.5 -33.8 14 58 A L > - 0 0 54 4,-3.2 3,-2.6 -2,-0.3 -1,-0.0 -0.674 24.8-106.4-102.2 156.4 -35.9 1.4 -36.9 15 59 A A T 3 S+ 0 0 119 1,-0.3 -1,-0.1 -2,-0.3 -2,-0.0 0.821 118.0 54.2 -54.4 -37.2 -37.1 0.7 -40.4 16 60 A D T 3 S- 0 0 105 1,-0.1 -1,-0.3 0, 0.0 3,-0.1 0.440 124.5 -96.7 -80.8 3.5 -35.5 -2.8 -40.4 17 61 A G S < S+ 0 0 42 -3,-2.6 -2,-0.1 1,-0.4 -1,-0.1 0.226 87.7 120.5 100.7 -13.6 -37.3 -3.9 -37.1 18 62 A Q - 0 0 50 -5,-0.1 -4,-3.2 110,-0.1 -1,-0.4 -0.232 53.6-138.6 -72.0 171.3 -34.4 -3.1 -34.8 19 63 A M E -B 13 0A 9 108,-2.1 2,-0.3 -6,-0.3 -6,-0.2 -0.994 21.4-179.3-136.2 142.3 -34.8 -0.7 -31.9 20 64 A G E -B 12 0A 0 -8,-2.8 -8,-2.7 -2,-0.3 2,-0.3 -0.969 23.3-129.9-144.3 153.8 -32.4 2.0 -30.7 21 65 A Y E +BC 11 29A 0 8,-0.9 8,-2.7 107,-0.4 2,-0.3 -0.744 32.3 169.8 -94.4 154.3 -31.9 4.7 -28.2 22 66 A G E -B 10 0A 1 -12,-2.0 -12,-2.4 -2,-0.3 6,-0.2 -0.991 45.8-126.9-155.9 162.1 -30.8 8.2 -29.1 23 67 A F S S+ 0 0 86 4,-0.4 2,-0.3 -2,-0.3 -15,-0.2 0.644 101.9 33.2 -80.9 -16.2 -30.4 11.7 -27.8 24 68 A E S > S- 0 0 115 3,-0.2 3,-2.1 -14,-0.1 2,-0.2 -0.995 94.4-100.4-139.9 142.8 -32.5 13.0 -30.8 25 69 A K T 3 S+ 0 0 141 -2,-0.3 -4,-0.0 1,-0.3 -2,-0.0 -0.461 112.5 22.6 -62.3 135.3 -35.4 11.6 -32.7 26 70 A G T 3 S+ 0 0 64 -2,-0.2 -1,-0.3 -4,-0.0 -14,-0.0 0.334 108.5 81.6 83.2 -2.4 -34.2 10.1 -35.9 27 71 A K < + 0 0 145 -3,-2.1 -4,-0.4 -7,-0.1 -3,-0.2 -0.205 57.0 146.7-123.4 41.9 -30.6 9.7 -34.6 28 72 A A - 0 0 23 -6,-0.2 2,-0.3 -8,-0.1 -6,-0.3 -0.508 25.7-169.4 -74.3 143.5 -31.0 6.4 -32.7 29 73 A S B -C 21 0A 50 -8,-2.7 -8,-0.9 -2,-0.2 -2,-0.1 -0.956 22.0-110.9-134.8 157.8 -28.0 4.2 -32.7 30 74 A V S S+ 0 0 33 -2,-0.3 2,-0.2 -10,-0.2 101,-0.1 -0.985 113.1 34.4-125.9 114.5 -27.1 0.6 -31.7 31 75 A P S S- 0 0 19 0, 0.0 100,-0.3 0, 0.0 3,-0.1 0.609 112.4-120.6 -64.0 161.5 -25.3 0.6 -29.3 32 76 A G - 0 0 5 98,-3.3 -10,-0.1 96,-0.2 -2,-0.1 -0.099 43.2 -70.3 -61.7 168.7 -27.0 3.7 -27.9 33 77 A P - 0 0 26 0, 0.0 2,-0.2 0, 0.0 -1,-0.2 -0.311 53.8-100.1 -71.3 151.0 -25.1 6.8 -27.2 34 78 A L - 0 0 55 -3,-0.1 2,-0.5 97,-0.1 99,-0.2 -0.432 28.2-158.0 -68.8 130.2 -22.5 7.0 -24.4 35 79 A I E -f 133 0B 5 97,-2.0 99,-2.6 -2,-0.2 2,-0.4 -0.964 15.3-176.9-108.1 126.8 -23.5 8.6 -21.2 36 80 A E E +f 134 0B 79 -2,-0.5 2,-0.3 97,-0.2 99,-0.2 -0.989 9.2 157.1-129.1 129.1 -20.5 9.9 -19.2 37 81 A V E -f 135 0B 5 97,-2.3 99,-2.6 -2,-0.4 2,-0.3 -0.878 35.6-111.9-139.3 169.3 -20.6 11.5 -15.7 38 82 A N E > -f 136 0B 76 -2,-0.3 3,-2.6 97,-0.2 -35,-0.2 -0.837 46.0 -89.5-100.9 147.0 -18.4 12.1 -12.7 39 83 A E T 3 S+ 0 0 10 97,-2.7 53,-0.2 -2,-0.3 3,-0.1 -0.293 118.3 34.6 -50.6 127.6 -18.9 10.6 -9.3 40 84 A G T 3 S+ 0 0 24 1,-0.5 -1,-0.3 -39,-0.1 50,-0.2 -0.108 92.2 119.5 113.2 -32.9 -21.2 12.9 -7.4 41 85 A D < - 0 0 4 -3,-2.6 49,-0.8 -39,-0.1 -1,-0.5 -0.256 50.9-149.0 -67.0 155.1 -23.2 13.9 -10.4 42 86 A T E -aD 4 89A 24 -39,-2.6 -37,-2.8 47,-0.2 2,-0.5 -0.965 8.9-158.0-120.8 138.1 -27.0 13.4 -10.8 43 87 A L E -aD 5 88A 6 45,-3.1 45,-2.9 -2,-0.4 2,-0.6 -0.981 5.5-164.7-122.2 123.4 -28.5 12.8 -14.2 44 88 A H E -aD 6 87A 42 -39,-2.6 -37,-2.1 -2,-0.5 2,-0.6 -0.962 13.0-163.8-105.7 115.6 -32.2 13.4 -14.9 45 89 A I E -aD 7 86A 0 41,-3.2 41,-2.7 -2,-0.6 2,-1.0 -0.906 11.8-152.6-106.7 115.5 -33.1 11.8 -18.2 46 90 A E E -aD 8 85A 80 -39,-3.0 -37,-2.0 -2,-0.6 2,-0.5 -0.774 25.7-166.6 -86.5 102.9 -36.3 12.8 -19.8 47 91 A F E -aD 9 84A 0 37,-2.9 37,-2.5 -2,-1.0 2,-0.5 -0.815 12.1-168.5-102.3 131.4 -37.1 9.7 -21.7 48 92 A T E -aD 10 83A 18 -39,-2.4 -37,-1.9 -2,-0.5 2,-0.9 -0.973 13.4-148.8-121.0 127.3 -39.7 9.4 -24.4 49 93 A N E +a 11 0A 0 33,-2.5 32,-2.1 -2,-0.5 33,-0.2 -0.832 17.8 176.2 -90.8 104.5 -40.9 6.1 -25.8 50 94 A T + 0 0 57 -39,-2.1 -38,-0.1 -2,-0.9 -1,-0.1 0.492 50.3 98.3 -86.0 -2.4 -41.7 6.8 -29.5 51 95 A M S S- 0 0 9 -40,-0.3 30,-0.5 2,-0.2 4,-0.1 -0.281 80.6-121.0 -85.8 172.2 -42.6 3.1 -30.1 52 96 A D S S+ 0 0 110 28,-0.2 2,-0.3 2,-0.1 -1,-0.1 0.351 94.2 61.8 -93.8 5.3 -45.9 1.3 -30.2 53 97 A V S S- 0 0 55 26,-0.1 28,-0.2 1,-0.0 -2,-0.2 -0.895 98.9 -89.8-123.3 155.4 -45.0 -1.1 -27.4 54 98 A R + 0 0 113 -2,-0.3 2,-0.3 61,-0.1 25,-0.2 -0.312 52.4 172.5 -56.7 149.1 -44.0 -0.4 -23.8 55 99 A A B -I 78 0C 0 23,-1.8 23,-2.4 -4,-0.1 2,-0.3 -0.953 9.5-172.8-155.6 165.0 -40.3 0.2 -23.2 56 100 A S - 0 0 0 -2,-0.3 2,-0.4 21,-0.2 59,-0.1 -0.920 24.5-118.5-152.1 176.2 -37.9 1.4 -20.4 57 101 A L + 0 0 0 19,-0.4 2,-0.4 -2,-0.3 56,-0.2 -0.988 28.4 177.1-123.8 121.0 -34.5 2.3 -19.4 58 102 A H E -G 112 0B 24 54,-3.0 54,-2.6 -2,-0.4 2,-0.4 -0.972 11.3-159.9-121.1 138.4 -32.7 0.3 -16.7 59 103 A V E -G 111 0B 0 -2,-0.4 2,-0.3 9,-0.3 52,-0.2 -0.910 9.0-137.0-122.2 145.6 -29.2 1.0 -15.7 60 104 A H S S+ 0 0 48 50,-2.6 2,-1.9 -2,-0.4 50,-0.2 -0.643 78.4 3.4 -89.4 151.3 -26.4 -1.0 -14.0 61 105 A G S S+ 0 0 34 -2,-0.3 -1,-0.1 48,-0.1 48,-0.0 -0.129 96.1 106.5 78.4 -44.2 -24.2 0.3 -11.2 62 106 A L S S- 0 0 9 -2,-1.9 2,-0.8 1,-0.1 28,-0.2 -0.275 78.3-103.1 -76.1 160.4 -25.6 3.8 -10.7 63 107 A D B +E 89 0A 54 26,-2.5 26,-3.6 -3,-0.1 2,-0.4 -0.736 53.1 160.6 -82.8 106.5 -27.7 4.8 -7.6 64 108 A Y - 0 0 79 -2,-0.8 24,-0.1 24,-0.2 2,-0.1 -0.955 37.1-120.7-124.0 148.1 -31.4 5.0 -8.7 65 109 A E > - 0 0 115 22,-0.5 3,-2.5 -2,-0.4 22,-0.1 -0.437 38.2 -99.7 -76.3 164.9 -34.5 4.9 -6.6 66 110 A I G > S+ 0 0 111 1,-0.3 3,-1.7 2,-0.2 5,-0.3 0.804 121.9 65.7 -58.6 -31.3 -37.1 2.1 -7.2 67 111 A S G 3 S+ 0 0 54 1,-0.3 -1,-0.3 2,-0.1 3,-0.2 0.628 104.9 46.0 -68.2 -10.8 -39.2 4.5 -9.3 68 112 A S G < S+ 0 0 7 -3,-2.5 -9,-0.3 1,-0.1 -1,-0.3 0.002 78.0 106.3-116.5 29.7 -36.3 4.5 -11.8 69 113 A D S < S- 0 0 16 -3,-1.7 -2,-0.1 5,-0.1 -1,-0.1 0.631 80.0-131.1 -83.2 -10.5 -35.6 0.8 -12.0 70 114 A G + 0 0 0 1,-0.2 44,-0.3 -4,-0.2 2,-0.2 0.596 60.4 130.4 77.1 11.9 -37.2 0.5 -15.4 71 115 A T > - 0 0 16 -5,-0.3 5,-2.6 1,-0.1 6,-0.4 -0.679 63.5-134.3-101.3 151.7 -39.4 -2.6 -14.5 72 116 A A T > 5S+ 0 0 34 42,-0.3 3,-2.4 -2,-0.2 5,-0.1 0.921 106.6 62.1 -59.0 -44.2 -43.1 -3.3 -15.1 73 117 A M T 3 5S+ 0 0 151 1,-0.3 -1,-0.2 46,-0.2 -3,-0.0 0.844 108.9 39.5 -55.6 -39.0 -43.3 -4.6 -11.5 74 118 A N T 3 5S- 0 0 52 -3,-0.1 -1,-0.3 -8,-0.1 -2,-0.2 0.152 113.0-115.7-101.3 22.3 -42.3 -1.2 -10.0 75 119 A K T < 5S+ 0 0 168 -3,-2.4 -3,-0.2 1,-0.1 -2,-0.1 0.893 78.5 128.2 53.5 45.4 -44.4 0.8 -12.6 76 120 A S < + 0 0 0 -5,-2.6 -19,-0.4 2,-0.1 -4,-0.2 0.248 39.0 94.1-122.5 6.1 -41.2 2.3 -13.9 77 121 A D S S- 0 0 14 -6,-0.4 2,-0.4 -5,-0.1 -21,-0.2 -0.350 71.7-114.5 -95.5-179.2 -41.7 1.5 -17.6 78 122 A V B -I 55 0C 0 -23,-2.4 -23,-1.8 -8,-0.1 3,-0.1 -0.973 16.8-130.1-131.5 123.7 -43.2 3.9 -20.3 79 123 A E > - 0 0 96 -2,-0.4 3,-2.4 -25,-0.2 -30,-0.3 -0.252 51.2 -72.2 -64.0 156.6 -46.4 3.5 -22.3 80 124 A P T 3 S+ 0 0 64 0, 0.0 -30,-0.2 0, 0.0 -1,-0.2 -0.315 123.1 7.3 -48.2 125.9 -46.3 3.9 -26.1 81 125 A G T 3 S+ 0 0 57 -32,-2.1 -31,-0.1 -30,-0.5 -2,-0.1 0.338 106.4 128.1 82.1 -5.4 -45.8 7.7 -26.9 82 126 A G < - 0 0 6 -3,-2.4 -33,-2.5 -33,-0.2 2,-0.4 -0.230 48.2-143.2 -85.6 174.6 -45.2 8.5 -23.2 83 127 A T E +D 48 0A 71 -35,-0.2 2,-0.3 -3,-0.1 -35,-0.2 -0.985 17.2 175.1-135.6 140.9 -42.5 10.3 -21.4 84 128 A R E -D 47 0A 75 -37,-2.5 -37,-2.9 -2,-0.4 2,-0.7 -0.991 27.4-130.2-144.2 143.8 -40.9 9.7 -18.0 85 129 A T E -D 46 0A 75 -2,-0.3 2,-0.4 -39,-0.2 -39,-0.2 -0.861 23.5-165.1 -95.0 114.6 -38.1 11.3 -16.1 86 130 A Y E -D 45 0A 0 -41,-2.7 -41,-3.2 -2,-0.7 2,-0.5 -0.808 6.5-150.9 -94.6 140.8 -35.6 8.8 -14.8 87 131 A T E -D 44 0A 22 -2,-0.4 2,-0.5 -43,-0.2 -22,-0.5 -0.967 11.7-174.4-117.1 123.0 -33.1 9.9 -12.2 88 132 A W E -D 43 0A 1 -45,-2.9 -45,-3.1 -2,-0.5 2,-0.3 -0.979 8.9-171.9-113.8 123.8 -29.6 8.3 -11.9 89 133 A R E -DE 42 63A 96 -26,-3.6 -26,-2.5 -2,-0.5 2,-0.3 -0.721 4.6-164.0-108.1 165.7 -27.4 9.4 -9.0 90 134 A T - 0 0 12 -49,-0.8 2,-0.3 -2,-0.3 -28,-0.1 -0.949 4.3-153.2-141.2 159.3 -23.8 8.6 -8.2 91 135 A H - 0 0 27 -2,-0.3 14,-2.3 -52,-0.1 15,-0.3 -0.943 15.6-120.3-134.1 159.0 -21.6 8.9 -5.2 92 136 A K - 0 0 105 -2,-0.3 12,-0.4 12,-0.2 10,-0.1 -0.623 39.7-101.3 -88.4 153.6 -18.0 9.4 -4.3 93 137 A P + 0 0 37 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.341 56.8 133.4 -73.1 159.7 -16.1 6.8 -2.2 94 138 A G E -J 102 0D 24 8,-1.8 8,-2.9 -2,-0.0 2,-0.3 -0.919 54.6 -68.0 168.6 167.0 -15.5 7.4 1.5 95 139 A R E -J 101 0D 168 -2,-0.3 6,-0.2 6,-0.2 2,-0.1 -0.567 40.5-144.3 -79.0 132.3 -15.6 5.9 5.0 96 140 A R > - 0 0 107 4,-3.1 3,-1.5 -2,-0.3 -1,-0.1 -0.401 32.3-103.7 -76.6 169.3 -19.0 5.1 6.6 97 141 A D T 3 S+ 0 0 181 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.854 122.7 65.2 -61.9 -30.6 -19.5 5.6 10.3 98 142 A D T 3 S- 0 0 117 1,-0.1 -1,-0.3 2,-0.1 3,-0.1 0.555 118.4-115.2 -72.5 -0.7 -19.3 1.8 10.6 99 143 A G S < S+ 0 0 42 -3,-1.5 2,-0.1 1,-0.3 -2,-0.1 0.339 77.1 123.0 86.7 -7.1 -15.6 2.2 9.5 100 144 A T - 0 0 64 -5,-0.1 -4,-3.1 1,-0.1 2,-0.6 -0.438 67.1-106.3 -81.9 165.8 -16.1 0.3 6.2 101 145 A W E -J 95 0D 130 -6,-0.2 -6,-0.2 -2,-0.1 -1,-0.1 -0.827 17.7-144.9-100.6 116.7 -15.4 1.9 2.8 102 146 A R E -J 94 0D 108 -8,-2.9 -8,-1.8 -2,-0.6 0, 0.0 -0.700 21.8-141.1 -76.0 128.6 -18.3 2.9 0.6 103 147 A P - 0 0 79 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.676 24.0-124.0 -77.4 -25.6 -16.9 2.1 -2.9 104 148 A G - 0 0 11 -12,-0.4 -12,-0.2 1,-0.1 33,-0.1 0.055 22.7 -97.0 93.0 155.6 -18.1 5.0 -5.2 105 149 A S S S+ 0 0 3 -14,-2.3 30,-0.2 31,-0.1 -1,-0.1 0.479 75.4 132.4 -81.5 -6.0 -20.1 4.6 -8.4 106 150 A A + 0 0 10 -15,-0.3 2,-0.3 -3,-0.1 30,-0.2 -0.181 36.2 80.8 -57.0 137.4 -17.0 4.8 -10.7 107 151 A G E S- H 0 135B 7 28,-2.0 28,-2.4 94,-0.0 2,-0.6 -0.939 81.2 -62.6 160.1-176.7 -16.8 2.2 -13.3 108 152 A Y E + H 0 134B 20 -2,-0.3 26,-0.2 26,-0.2 2,-0.2 -0.917 63.0 154.7-103.5 115.8 -17.9 0.9 -16.7 109 153 A W E - H 0 133B 71 24,-3.0 24,-1.9 -2,-0.6 2,-0.3 -0.483 23.9-148.6-130.5-168.5 -21.6 0.3 -16.7 110 154 A H E - H 0 132B 0 22,-0.3 -50,-2.6 -50,-0.2 2,-0.3 -0.985 6.7-136.6-165.8 164.3 -24.5 0.2 -19.2 111 155 A Y E +GH 59 131B 0 20,-2.7 20,-2.2 -2,-0.3 2,-0.3 -0.938 26.0 161.3-131.4 152.0 -28.2 0.8 -19.7 112 156 A H E -GH 58 130B 12 -54,-2.6 -54,-3.0 -2,-0.3 18,-0.2 -0.976 40.7 -82.0-162.8 165.5 -30.8 -1.3 -21.5 113 157 A D - 0 0 0 16,-1.9 12,-0.2 -2,-0.3 -56,-0.1 -0.477 27.5-171.4 -74.3 150.3 -34.5 -1.9 -21.9 114 158 A H S S+ 0 0 27 -44,-0.3 7,-0.5 -2,-0.2 -42,-0.3 0.321 74.8 39.7-126.3 7.1 -36.3 -4.1 -19.3 115 159 A V S S+ 0 0 20 5,-0.3 2,-0.5 6,-0.2 -61,-0.1 0.503 73.6 109.0-139.2 -7.3 -39.9 -4.6 -20.9 116 160 A V S S- 0 0 11 1,-0.2 8,-2.0 5,-0.1 7,-1.5 -0.671 100.6 -9.6 -79.2 123.4 -39.8 -5.2 -24.6 117 161 A G S S+ 0 0 68 -2,-0.5 2,-0.3 6,-0.3 -1,-0.2 -0.384 140.5 13.7 89.3 -55.0 -40.7 -8.8 -25.5 118 162 A T S > S- 0 0 65 -2,-1.1 3,-2.0 0, 0.0 6,-0.2 -0.903 88.9 -97.0-140.4 169.3 -40.5 -10.1 -21.9 119 163 A E T 3 S+ 0 0 133 -2,-0.3 -47,-0.2 1,-0.3 -46,-0.2 0.410 124.3 56.4 -71.7 1.3 -40.4 -8.5 -18.5 120 164 A H T 3 S- 0 0 134 -4,-0.1 -1,-0.3 -5,-0.1 -5,-0.3 0.237 117.4-111.5-110.4 10.7 -36.6 -8.9 -18.6 121 165 A G <> + 0 0 0 -3,-2.0 4,-3.2 -7,-0.5 5,-0.3 0.687 64.8 149.7 77.5 22.8 -36.3 -7.0 -21.8 122 166 A T H > S+ 0 0 49 1,-0.2 4,-1.8 2,-0.2 -5,-0.2 0.861 74.6 41.0 -59.6 -43.5 -35.2 -9.9 -23.9 123 167 A G H > S+ 0 0 15 -7,-1.5 4,-2.3 2,-0.2 -6,-0.3 0.901 115.8 50.4 -69.7 -41.7 -36.8 -8.6 -27.1 124 168 A G H >>S+ 0 0 0 -8,-2.0 5,-2.8 2,-0.2 4,-1.1 0.945 112.6 45.7 -62.8 -47.7 -35.6 -5.0 -26.5 125 169 A I H ><5S+ 0 0 18 -4,-3.2 3,-0.8 -9,-0.3 -1,-0.2 0.935 113.0 50.8 -59.2 -49.1 -32.0 -6.1 -25.8 126 170 A R H 3<5S+ 0 0 117 -4,-1.8 -1,-0.2 -5,-0.3 -2,-0.2 0.893 109.4 51.1 -56.8 -39.9 -32.0 -8.4 -28.8 127 171 A N H 3<5S- 0 0 45 -4,-2.3 -108,-2.1 -109,-0.1 -1,-0.2 0.638 130.5 -86.9 -77.3 -17.1 -33.3 -5.5 -31.1 128 172 A G T <<5S+ 0 0 0 -4,-1.1 2,-2.2 -3,-0.8 -107,-0.4 0.479 76.5 141.7 128.7 6.0 -30.6 -3.0 -30.0 129 173 A L < + 0 0 0 -5,-2.8 -16,-1.9 -109,-0.2 2,-0.3 -0.462 46.2 97.1 -83.4 75.1 -31.8 -1.3 -26.8 130 174 A Y E + H 0 112B 1 -2,-2.2 -98,-3.3 -18,-0.2 -18,-0.2 -0.983 39.3 161.2-152.4 152.6 -28.5 -1.1 -25.0 131 175 A G E - H 0 111B 0 -20,-2.2 -20,-2.7 -2,-0.3 2,-0.2 -0.978 33.6 -90.0-166.7 168.9 -25.7 1.4 -24.5 132 176 A P E - H 0 110B 1 0, 0.0 -97,-2.0 0, 0.0 2,-0.4 -0.554 22.9-167.8 -93.1 149.9 -22.8 2.3 -22.3 133 177 A V E -fH 35 109B 0 -24,-1.9 -24,-3.0 -2,-0.2 2,-0.4 -0.999 4.8-165.9-128.8 134.8 -22.4 4.4 -19.3 134 178 A I E -fH 36 108B 2 -99,-2.6 -97,-2.3 -2,-0.4 2,-0.5 -0.986 3.4-166.7-120.0 130.0 -19.1 5.6 -17.8 135 179 A V E -fH 37 107B 2 -28,-2.4 -28,-2.0 -2,-0.4 2,-0.3 -0.986 16.1-153.0-112.2 121.4 -18.7 7.0 -14.3 136 180 A R E -f 38 0B 8 -99,-2.6 -97,-2.7 -2,-0.5 2,-0.3 -0.700 5.5-139.9 -95.6 142.6 -15.3 8.7 -13.7 137 181 A R > - 0 0 63 -2,-0.3 3,-2.5 -99,-0.2 -45,-0.0 -0.750 42.5 -87.7 -89.4 147.4 -13.5 9.2 -10.5 138 182 A K T 3 S+ 0 0 202 -2,-0.3 -1,-0.1 1,-0.3 -100,-0.0 -0.344 118.4 21.2 -51.2 125.8 -11.8 12.5 -9.8 139 183 A G T 3 S+ 0 0 76 1,-0.3 -1,-0.3 -3,-0.0 2,-0.0 0.373 86.4 145.7 92.6 -5.3 -8.3 12.1 -11.2 140 184 A D < - 0 0 37 -3,-2.5 2,-0.3 1,-0.1 -1,-0.3 -0.381 57.2-104.9 -61.5 145.0 -9.1 9.2 -13.6 141 185 A V - 0 0 72 -2,-0.0 -1,-0.1 1,-0.0 0, 0.0 -0.584 34.2-144.1 -72.9 132.2 -7.1 9.3 -16.9 142 186 A L - 0 0 108 -2,-0.3 2,-0.1 -3,-0.0 32,-0.1 -0.758 12.4-134.8-101.8 142.6 -9.2 10.4 -19.9 143 187 A P - 0 0 27 0, 0.0 32,-0.2 0, 0.0 3,-0.1 -0.408 18.0-121.4 -94.4 168.1 -8.8 8.9 -23.4 144 188 A D S S- 0 0 116 30,-2.8 2,-0.3 1,-0.3 31,-0.2 0.827 97.3 -2.3 -71.1 -34.2 -8.5 10.4 -26.9 145 189 A A E -k 175 0E 41 29,-1.1 31,-2.7 2,-0.0 2,-0.4 -0.989 62.0-142.1-156.7 152.7 -11.6 8.4 -27.9 146 190 A T E -k 176 0E 37 -2,-0.3 2,-0.4 29,-0.2 31,-0.2 -0.980 15.4-169.8-121.3 128.0 -14.0 5.8 -26.5 147 191 A H E -k 177 0E 38 29,-2.7 31,-2.4 -2,-0.4 2,-0.5 -0.923 12.9-142.9-116.1 142.1 -15.3 2.9 -28.5 148 192 A T E -k 178 0E 18 -2,-0.4 2,-0.5 29,-0.2 31,-0.2 -0.914 14.0-173.2-108.2 124.5 -18.1 0.6 -27.4 149 193 A I E -k 179 0E 3 29,-2.9 31,-2.3 -2,-0.5 2,-0.5 -0.968 5.5-175.9-119.9 117.7 -18.0 -3.1 -28.3 150 194 A V E -k 180 0E 0 -2,-0.5 7,-2.7 29,-0.2 2,-0.9 -0.954 18.8-154.1-119.1 121.8 -21.1 -5.2 -27.4 151 195 A F E -kL 181 156E 0 29,-2.3 31,-2.8 -2,-0.5 2,-0.7 -0.834 21.6-179.7 -89.7 102.8 -21.3 -8.9 -27.9 152 196 A N E > -kL 182 155E 3 3,-1.9 3,-2.1 -2,-0.9 31,-0.2 -0.935 60.8 -57.2-111.6 110.1 -25.1 -9.3 -28.3 153 197 A D T 3 S- 0 0 22 29,-2.3 29,-0.1 -2,-0.7 -27,-0.0 -0.403 121.7 -19.7 46.5-119.0 -25.8 -13.0 -28.8 154 198 A M T 3 S+ 0 0 62 -2,-0.1 2,-0.3 -3,-0.1 -1,-0.3 0.015 125.1 83.3-102.6 26.6 -23.7 -13.9 -31.9 155 199 A T E < S-L 152 0E 41 -3,-2.1 -3,-1.9 99,-0.1 2,-0.6 -0.851 70.6-133.6-123.0 157.9 -23.3 -10.4 -33.1 156 200 A I E > S-L 151 0E 5 3,-0.4 3,-2.2 -2,-0.3 -5,-0.2 -0.984 96.7 -17.8-104.1 119.9 -21.0 -7.5 -32.4 157 201 A N T 3 S- 0 0 18 -7,-2.7 -1,-0.1 -2,-0.6 -127,-0.1 0.837 121.0 -66.0 53.6 36.6 -23.2 -4.3 -32.0 158 202 A N T 3 S+ 0 0 28 -8,-0.3 -1,-0.3 1,-0.2 2,-0.1 0.589 97.5 148.8 61.3 14.7 -26.0 -6.2 -33.8 159 203 A R < - 0 0 118 -3,-2.2 -3,-0.4 5,-0.1 -1,-0.2 -0.420 53.8-101.4 -77.0 152.5 -24.0 -6.3 -37.0 160 204 A K > - 0 0 163 1,-0.2 3,-1.0 -2,-0.1 -4,-0.1 -0.289 59.9 -72.3 -61.7 156.3 -24.2 -9.0 -39.6 161 205 A P T 3 S+ 0 0 84 0, 0.0 92,-0.2 0, 0.0 -1,-0.2 -0.214 114.9 8.8 -54.6 139.7 -21.4 -11.6 -39.5 162 206 A H T 3 S+ 0 0 123 91,-1.6 92,-0.1 2,-0.1 91,-0.1 0.793 95.0 109.6 62.0 33.8 -18.0 -10.5 -40.7 163 207 A T < - 0 0 64 -3,-1.0 3,-0.2 1,-0.5 -3,-0.1 -0.020 61.4-159.2-123.9 30.3 -18.9 -6.8 -41.0 164 208 A G - 0 0 8 91,-0.7 -1,-0.5 1,-0.2 -8,-0.3 -0.533 30.3-122.8 79.2-144.8 -16.8 -5.4 -38.0 165 209 A P - 0 0 11 0, 0.0 2,-0.3 0, 0.0 92,-0.3 0.383 42.0-162.7 -73.5 159.1 -17.3 -2.9 -36.6 166 210 A D - 0 0 82 -3,-0.2 2,-0.3 90,-0.2 92,-0.2 -0.858 4.1-161.1-109.7 148.5 -13.8 -1.6 -37.2 167 211 A F E -n 258 0F 29 90,-2.3 92,-3.1 -2,-0.3 2,-0.4 -0.933 7.5-145.5-127.3 150.6 -12.2 1.3 -35.3 168 212 A E E +n 259 0F 115 -2,-0.3 2,-0.3 90,-0.2 92,-0.2 -0.928 23.0 157.8-124.6 146.5 -9.2 3.4 -36.3 169 213 A A E -n 260 0F 3 90,-2.5 92,-3.2 -2,-0.4 2,-0.4 -0.930 34.0-117.7-148.8 169.6 -6.4 5.0 -34.4 170 214 A T E > -n 261 0F 49 -2,-0.3 3,-3.0 90,-0.2 61,-0.2 -0.915 48.9 -84.3-112.2 146.1 -2.9 6.3 -34.9 171 215 A V T 3 S+ 0 0 58 90,-2.5 61,-0.2 -2,-0.4 60,-0.1 -0.167 119.3 25.2 -45.4 127.7 0.1 4.9 -33.1 172 216 A G T 3 S+ 0 0 42 59,-2.9 -1,-0.3 1,-0.3 60,-0.1 0.228 85.6 135.2 97.4 -15.9 0.3 6.5 -29.7 173 217 A D < - 0 0 54 -3,-3.0 58,-3.0 58,-0.1 2,-0.9 -0.414 58.3-125.1 -62.0 142.3 -3.5 7.4 -29.3 174 218 A R E - M 0 230E 70 56,-0.2 -30,-2.8 -2,-0.1 -29,-1.1 -0.839 35.6-169.5 -89.2 107.3 -5.0 6.7 -25.9 175 219 A V E -kM 145 229E 2 54,-2.7 54,-2.6 -2,-0.9 2,-0.4 -0.861 10.8-156.8-108.3 130.4 -8.0 4.5 -26.8 176 220 A E E -kM 146 228E 0 -31,-2.7 -29,-2.7 -2,-0.4 2,-0.4 -0.881 5.8-163.2-106.5 134.1 -10.7 3.5 -24.3 177 221 A I E -kM 147 227E 3 50,-2.7 50,-1.9 -2,-0.4 2,-0.5 -0.975 7.1-163.0-117.7 133.2 -12.8 0.4 -24.9 178 222 A V E -kM 148 226E 0 -31,-2.4 -29,-2.9 -2,-0.4 2,-0.6 -0.981 15.9-163.8-110.3 122.1 -16.2 -0.3 -23.1 179 223 A M E +kM 149 225E 0 46,-3.2 46,-2.0 -2,-0.5 2,-0.4 -0.948 12.6 172.9-120.3 115.7 -17.0 -4.0 -23.5 180 224 A I E -kM 150 224E 1 -31,-2.3 -29,-2.3 -2,-0.6 2,-0.4 -0.926 14.3-157.1-124.0 144.9 -20.5 -5.2 -22.8 181 225 A T E +k 151 0E 0 42,-2.0 41,-3.2 -2,-0.4 2,-0.3 -0.954 15.5 171.5-123.3 145.0 -22.2 -8.5 -23.3 182 226 A H E +k 152 0E 5 -31,-2.8 -29,-2.3 -2,-0.4 2,-0.5 -0.980 34.6 25.7-143.4 159.7 -25.9 -9.4 -23.7 183 227 A G S S- 0 0 25 -2,-0.3 -31,-0.1 -31,-0.2 -2,-0.0 -0.824 100.0 -31.2 106.8-126.8 -28.2 -12.2 -24.5 184 228 A E S S+ 0 0 115 -2,-0.5 2,-0.2 36,-0.1 -1,-0.2 0.656 102.0 75.5-112.0 -24.4 -27.9 -16.0 -24.2 185 229 A Y - 0 0 106 -3,-0.4 2,-0.3 35,-0.1 -32,-0.2 -0.641 62.9-132.9-110.8 151.5 -24.2 -16.8 -24.7 186 230 A Y - 0 0 131 -2,-0.2 2,-0.3 34,-0.2 34,-0.2 -0.644 34.2-177.6 -82.5 154.3 -20.9 -16.6 -22.9 187 231 A H E -O 219 0F 0 32,-2.4 32,-2.5 -2,-0.3 2,-0.4 -0.904 27.0-132.0-143.2 167.9 -18.0 -15.2 -24.9 188 232 A T E -O 218 0F 24 -2,-0.3 57,-2.5 30,-0.2 2,-0.5 -0.957 20.8-149.0-126.4 113.0 -14.2 -14.5 -24.6 189 233 A F E +OP 217 244F 0 28,-2.4 28,-1.5 -2,-0.4 2,-0.4 -0.692 22.1 178.0 -80.6 125.7 -13.2 -11.0 -25.7 190 234 A H E -OP 216 243F 21 53,-2.4 53,-2.4 -2,-0.5 2,-0.4 -0.992 15.5-165.5-131.2 135.2 -9.6 -11.0 -27.2 191 235 A M E > - P 0 242F 5 24,-1.5 3,-0.7 -2,-0.4 51,-0.2 -0.987 19.0-134.9-116.8 128.5 -7.5 -8.2 -28.7 192 236 A H T 3 S+ 0 0 68 49,-3.2 48,-0.1 -2,-0.4 66,-0.1 -0.487 85.6 9.1 -69.2 139.4 -4.4 -8.8 -30.8 193 237 A G T 3 S+ 0 0 17 -2,-0.2 2,-0.3 1,-0.1 -1,-0.2 0.363 114.2 78.1 82.4 -7.7 -1.3 -6.6 -30.0 194 238 A H < - 0 0 5 -3,-0.7 2,-0.3 21,-0.1 -3,-0.3 -0.953 51.7-172.9-141.0 151.4 -2.7 -5.0 -26.9 195 239 A R - 0 0 114 -2,-0.3 2,-0.3 -3,-0.1 20,-0.2 -0.925 2.2-171.6-141.1 164.0 -3.2 -5.9 -23.2 196 240 A W E -R 214 0G 9 18,-2.4 18,-2.9 -2,-0.3 2,-0.4 -0.942 30.9 -93.9-152.4 169.1 -4.8 -4.4 -20.1 197 241 A A E -R 213 0G 4 5,-2.4 2,-2.0 -2,-0.3 16,-0.2 -0.750 31.1-128.2 -89.2 135.8 -5.2 -4.9 -16.4 198 242 A D S S+ 0 0 57 14,-2.9 14,-0.3 -2,-0.4 2,-0.2 -0.439 76.1 92.0 -80.2 70.1 -8.2 -6.9 -15.1 199 243 A N S S- 0 0 40 -2,-2.0 27,-0.3 27,-0.2 5,-0.1 -0.712 94.8 -65.7-145.2-165.5 -9.3 -4.2 -12.6 200 244 A R S S+ 0 0 87 1,-0.2 26,-0.3 -2,-0.2 -92,-0.2 0.928 129.2 22.4 -56.6 -54.5 -11.7 -1.2 -12.4 201 245 A T S S- 0 0 31 2,-0.3 27,-0.3 24,-0.1 -1,-0.2 0.517 99.3-119.6 -92.2 -10.4 -9.9 1.1 -14.9 202 246 A G S S+ 0 0 3 1,-0.2 -5,-2.4 25,-0.2 2,-0.4 0.532 86.4 101.3 79.6 4.4 -8.0 -1.5 -16.9 203 247 A I S S- 0 0 56 -7,-0.2 -2,-0.3 24,-0.1 -1,-0.2 -0.970 77.5-119.6-124.6 131.3 -4.8 0.3 -15.8 204 248 A L - 0 0 65 -2,-0.4 -7,-0.0 1,-0.1 9,-0.0 -0.507 15.2-137.4 -69.3 142.9 -2.5 -0.9 -13.0 205 249 A T - 0 0 126 1,-0.2 -1,-0.1 -2,-0.1 -2,-0.0 0.723 65.9 -70.3 -70.8 -21.7 -2.2 1.6 -10.1 206 250 A G S > S- 0 0 29 3,-0.1 3,-1.8 1,-0.0 -1,-0.2 -0.968 77.6 -36.2 156.8-163.8 1.6 0.9 -10.0 207 251 A P T 3 S+ 0 0 131 0, 0.0 -1,-0.0 0, 0.0 -2,-0.0 0.667 128.4 56.3 -66.2 -16.8 4.1 -1.7 -8.9 208 252 A D T 3 S+ 0 0 151 2,-0.0 -4,-0.0 -4,-0.0 0, 0.0 0.365 78.1 104.0 -95.6 2.5 2.0 -2.9 -6.0 209 253 A D < - 0 0 26 -3,-1.8 -3,-0.1 1,-0.1 -5,-0.0 -0.786 50.0-171.4 -86.4 111.7 -1.2 -3.7 -8.0 210 254 A P + 0 0 126 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.355 34.9 137.2 -86.4 7.5 -1.3 -7.5 -8.4 211 255 A S - 0 0 36 1,-0.1 2,-0.1 -14,-0.0 -12,-0.1 -0.231 63.4-101.6 -57.2 142.4 -4.2 -7.5 -10.9 212 256 A R - 0 0 175 -14,-0.3 -14,-2.9 -15,-0.1 2,-0.5 -0.422 27.0-137.3 -63.9 136.9 -3.7 -10.0 -13.8 213 257 A V E +R 197 0G 75 -16,-0.2 2,-0.3 -2,-0.1 -16,-0.2 -0.870 39.5 167.7 -95.7 127.0 -2.6 -8.4 -17.1 214 258 A I E -R 196 0G 20 -18,-2.9 -18,-2.4 -2,-0.5 3,-0.1 -0.844 45.8-166.0-138.4 165.5 -4.6 -10.0 -19.8 215 259 A D S S+ 0 0 69 -2,-0.3 -24,-1.5 1,-0.2 2,-0.3 0.172 83.9 54.2-133.7 12.8 -5.6 -9.9 -23.4 216 260 A N E +O 190 0F 59 -26,-0.2 2,-0.3 2,-0.0 -1,-0.2 -0.985 61.2 177.9-152.2 133.0 -8.5 -12.4 -23.2 217 261 A K E -O 189 0F 51 -28,-1.5 -28,-2.4 -2,-0.3 2,-0.2 -0.972 25.7-130.9-151.3 123.8 -11.6 -12.3 -20.9 218 262 A I E +O 188 0F 112 -2,-0.3 2,-0.3 -30,-0.2 -30,-0.2 -0.541 34.0 176.2 -72.6 138.0 -14.7 -14.5 -20.4 219 263 A T E -O 187 0F 6 -32,-2.5 -32,-2.4 -2,-0.2 -39,-0.1 -0.969 10.8-169.8-139.6 152.3 -17.9 -12.5 -20.3 220 264 A G > - 0 0 16 -2,-0.3 3,-2.4 -34,-0.2 -39,-0.3 -0.826 48.8 -39.1-134.8-179.6 -21.6 -13.3 -20.0 221 265 A P T 3 S+ 0 0 65 0, 0.0 -39,-0.3 0, 0.0 3,-0.1 -0.132 125.2 4.4 -50.6 125.2 -24.9 -11.5 -20.3 222 266 A A T 3 S+ 0 0 28 -41,-3.2 2,-0.2 1,-0.3 -40,-0.1 0.391 90.8 140.2 78.1 8.8 -24.9 -8.0 -18.8 223 267 A D < - 0 0 82 -3,-2.4 -42,-2.0 -42,-0.1 2,-0.4 -0.532 28.5-173.8 -72.0 144.5 -21.2 -8.1 -17.9 224 268 A S E +M 180 0E 33 -44,-0.2 2,-0.3 -2,-0.2 -44,-0.2 -0.999 14.0 151.5-138.9 138.5 -19.4 -4.8 -18.4 225 269 A F E -M 179 0E 23 -46,-2.0 -46,-3.2 -2,-0.4 2,-0.3 -0.951 16.2-165.9-146.9 171.1 -15.8 -3.8 -18.2 226 270 A G E +M 178 0E 3 -26,-0.3 2,-0.3 -27,-0.3 -48,-0.2 -0.980 6.9 175.7-155.2 165.4 -13.5 -1.3 -19.8 227 271 A F E -M 177 0E 0 -50,-1.9 -50,-2.7 -2,-0.3 2,-0.4 -0.969 23.3-125.3-159.8 168.2 -9.9 -0.4 -20.3 228 272 A Q E -M 176 0E 12 -27,-0.3 2,-0.3 -2,-0.3 -52,-0.2 -0.979 24.6-178.7-122.6 139.8 -7.5 2.1 -22.0 229 273 A I E -M 175 0E 10 -54,-2.6 -54,-2.7 -2,-0.4 2,-0.7 -0.949 32.3-120.1-128.5 154.1 -4.6 1.1 -24.2 230 274 A I E > -M 174 0E 38 -2,-0.3 3,-2.3 -56,-0.2 -56,-0.2 -0.874 44.4-116.0 -89.4 114.0 -1.9 3.1 -26.0 231 275 A A T 3 S- 0 0 0 -58,-3.0 -59,-2.9 -2,-0.7 -58,-0.1 -0.256 91.9 -1.1 -56.9 127.9 -2.6 2.2 -29.7 232 276 A G T >> S+ 0 0 3 1,-0.2 4,-2.9 -61,-0.2 3,-2.0 0.546 85.6 169.7 72.9 8.0 0.5 0.3 -31.1 233 277 A E T <4 S- 0 0 119 -3,-2.3 -1,-0.2 1,-0.3 -3,-0.1 -0.348 74.4 -14.0 -64.1 118.5 2.5 0.6 -27.9 234 278 A G T 34 S+ 0 0 86 -2,-0.2 -1,-0.3 1,-0.1 -2,-0.1 0.472 139.0 62.3 74.6 1.2 5.6 -1.6 -28.2 235 279 A V T <4 S- 0 0 56 -3,-2.0 -2,-0.2 1,-0.1 -1,-0.1 0.535 89.0-146.1-133.6 -20.8 4.0 -3.3 -31.3 236 280 A G < - 0 0 30 -4,-2.9 -4,-0.1 -5,-0.1 24,-0.1 -0.165 41.5 -21.3 82.3-172.1 3.6 -0.6 -34.0 237 281 A A S S+ 0 0 21 -6,-0.1 2,-0.3 -66,-0.1 24,-0.2 -0.269 73.7 121.2 -71.7 155.8 1.0 -0.0 -36.7 238 282 A G E - Q 0 260F 10 22,-2.2 22,-2.7 28,-0.1 2,-1.3 -0.893 69.4 -83.2 165.2 162.5 -1.2 -2.8 -38.1 239 283 A A E - Q 0 259F 43 29,-0.3 2,-0.7 -2,-0.3 20,-0.2 -0.780 55.0-167.3 -85.7 89.8 -4.7 -4.2 -38.8 240 284 A W E - Q 0 258F 51 18,-2.3 18,-3.0 -2,-1.3 -2,-0.1 -0.753 10.3-137.4 -88.5 112.9 -5.0 -5.7 -35.3 241 285 A M E - Q 0 257F 62 -2,-0.7 -49,-3.2 16,-0.2 2,-0.3 -0.345 17.8-172.3 -64.9 144.5 -7.9 -8.1 -34.9 242 286 A Y E +PQ 191 256F 2 14,-2.0 14,-2.6 -51,-0.2 2,-0.3 -0.955 24.7 143.6-125.1 147.9 -10.2 -8.2 -32.0 243 287 A H E -PQ 190 255F 14 -53,-2.4 -53,-2.4 -2,-0.3 2,-0.4 -0.987 56.4 -84.9-167.9 163.8 -12.7 -11.1 -31.7 244 288 A C E -P 189 0F 0 10,-2.2 -55,-0.2 -2,-0.3 9,-0.1 -0.709 37.1-149.0 -71.7 140.0 -14.6 -13.5 -29.6 245 289 A H + 0 0 71 -57,-2.5 2,-0.4 -2,-0.4 -1,-0.1 0.507 63.3 114.8 -98.7 -4.3 -12.2 -16.4 -29.1 246 290 A V S >> S- 0 0 22 -58,-0.3 4,-2.1 1,-0.2 3,-0.6 -0.541 73.9-132.9 -58.4 121.9 -14.9 -19.0 -28.8 247 291 A Q H 3> S+ 0 0 111 -2,-0.4 4,-2.4 1,-0.3 5,-0.2 0.878 99.2 45.3 -63.3 -43.4 -13.8 -20.8 -32.0 248 292 A S H 3> S+ 0 0 60 1,-0.2 4,-1.5 2,-0.2 -1,-0.3 0.821 112.3 55.8 -67.4 -24.6 -17.1 -21.2 -33.7 249 293 A H H <4>S+ 0 0 18 -3,-0.6 5,-2.5 2,-0.2 4,-0.3 0.918 109.7 42.3 -74.0 -44.0 -18.0 -17.6 -32.9 250 294 A S H ><5S+ 0 0 18 -4,-2.1 3,-1.6 3,-0.2 -2,-0.2 0.944 115.3 51.7 -66.1 -44.9 -14.9 -16.1 -34.5 251 295 A D H 3<5S+ 0 0 117 -4,-2.4 -2,-0.2 1,-0.3 -1,-0.2 0.811 108.9 51.4 -58.5 -31.9 -15.4 -18.5 -37.5 252 296 A M T 3<5S- 0 0 118 -4,-1.5 -1,-0.3 -5,-0.2 -2,-0.2 0.389 133.4 -82.5 -91.2 1.9 -19.1 -17.4 -37.8 253 297 A G T < 5S+ 0 0 6 -3,-1.6 2,-2.0 -4,-0.3 -91,-1.6 0.500 80.9 135.1 119.8 5.0 -18.2 -13.7 -37.8 254 298 A M < + 0 0 2 -5,-2.5 -10,-2.2 -93,-0.1 2,-0.3 -0.419 52.6 107.5 -80.8 66.2 -17.6 -12.2 -34.4 255 299 A V E + Q 0 243F 26 -2,-2.0 -91,-0.7 -12,-0.2 2,-0.3 -0.983 36.8 161.7-141.4 144.1 -14.4 -10.4 -35.6 256 300 A G E - Q 0 242F 3 -14,-2.6 -14,-2.0 -2,-0.3 2,-0.4 -0.880 31.0-103.6-148.7-172.3 -13.5 -6.9 -36.3 257 301 A L E - Q 0 241F 53 -92,-0.3 -90,-2.3 -2,-0.3 2,-0.7 -0.952 4.2-156.5-126.4 138.5 -10.4 -4.7 -36.7 258 302 A F E -nQ 167 240F 3 -18,-3.0 -18,-2.3 -2,-0.4 2,-1.0 -0.940 27.1-156.5-103.0 99.3 -8.5 -2.2 -34.6 259 303 A L E -nQ 168 239F 29 -92,-3.1 -90,-2.5 -2,-0.7 2,-0.7 -0.722 9.9-171.3 -88.3 100.2 -6.8 -0.3 -37.5 260 304 A V E -nQ 169 238F 0 -22,-2.7 -22,-2.2 -2,-1.0 -90,-0.2 -0.847 12.9-154.9 -99.2 114.8 -3.7 1.4 -36.0 261 305 A K E -n 170 0F 47 -92,-3.2 -90,-2.5 -2,-0.7 6,-0.2 -0.595 12.9-119.6 -92.8 148.1 -2.2 3.7 -38.5 262 306 A K > - 0 0 80 4,-2.8 3,-2.4 -2,-0.2 -1,-0.1 -0.271 46.1 -93.1 -65.2 165.3 1.4 5.0 -38.9 263 307 A P T 3 S+ 0 0 126 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.708 129.2 61.8 -55.9 -21.0 1.9 8.8 -38.8 264 308 A D T 3 S- 0 0 109 2,-0.2 3,-0.1 1,-0.0 -2,-0.0 0.308 119.6-111.0 -84.7 5.0 1.5 8.7 -42.6 265 309 A G S < S+ 0 0 45 -3,-2.4 2,-0.3 1,-0.3 -4,-0.0 0.511 76.8 122.8 83.9 5.9 -2.0 7.3 -42.2 266 310 A T - 0 0 21 5,-0.1 -4,-2.8 6,-0.0 -1,-0.3 -0.715 56.0-137.4-107.7 156.6 -1.3 3.9 -43.6 267 311 A I > - 0 0 18 -2,-0.3 3,-2.8 3,-0.3 -6,-0.1 -0.934 42.6 -99.3-103.7 123.3 -1.6 0.3 -42.3 268 312 A P T 3 S+ 0 0 53 0, 0.0 -29,-0.3 0, 0.0 -1,-0.0 -0.144 107.0 6.0 -46.9 125.2 1.4 -2.0 -43.1 269 313 A G T 3 S+ 0 0 61 -31,-0.1 -31,-0.0 1,-0.0 -3,-0.0 0.322 121.9 72.8 82.9 -8.1 0.5 -4.2 -46.2 270 314 A Y < + 0 0 188 -3,-2.8 -3,-0.3 2,-0.0 3,-0.1 -0.164 61.1 156.6-131.3 42.2 -2.8 -2.4 -46.8 271 315 A E - 0 0 86 -5,-0.1 -5,-0.1 1,-0.1 -6,-0.0 -0.362 50.4 -99.7 -67.1 141.6 -1.7 1.0 -48.2 272 316 A P 0 0 108 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 -0.352 360.0 360.0 -58.9 145.5 -4.3 2.8 -50.4 273 317 A H 0 0 245 -3,-0.1 -3,-0.0 0, 0.0 -2,-0.0 0.853 360.0 360.0 -85.7 360.0 -3.7 2.5 -54.2