==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/DNA 20-FEB-02 1L2D . COMPND 2 MOLECULE: 5'- . SOURCE 2 SYNTHETIC: YES; . AUTHOR J.C.FROMME,G.L.VERDINE . 259 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11489.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 179 69.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 52 20.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 5.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 62 23.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 0 2 0 0 1 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 0 0 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A P 0 0 48 0, 0.0 2,-0.2 0, 0.0 74,-0.1 0.000 360.0 360.0 360.0 156.6 -17.1 52.4 21.0 2 3 A E >> - 0 0 19 170,-0.1 4,-2.5 56,-0.0 3,-0.6 -0.481 360.0 -67.3-111.9-174.9 -14.9 49.4 20.1 3 4 A L H 3> S+ 0 0 0 167,-2.3 4,-2.8 1,-0.2 5,-0.2 0.857 131.0 50.4 -44.0 -49.4 -14.8 47.5 16.8 4 5 A P H 3> S+ 0 0 0 0, 0.0 4,-1.8 0, 0.0 -1,-0.2 0.895 113.2 44.3 -59.5 -43.1 -18.3 46.0 17.0 5 6 A E H <> S+ 0 0 29 -3,-0.6 4,-1.8 2,-0.2 -2,-0.2 0.911 116.0 47.2 -69.1 -41.2 -20.0 49.3 17.7 6 7 A V H X S+ 0 0 1 -4,-2.5 4,-2.5 2,-0.2 -1,-0.2 0.879 110.6 52.1 -67.9 -37.2 -18.0 51.1 15.0 7 8 A E H X S+ 0 0 33 -4,-2.8 4,-2.0 -5,-0.3 -1,-0.2 0.891 108.7 51.5 -65.7 -37.1 -18.7 48.4 12.5 8 9 A T H X S+ 0 0 42 -4,-1.8 4,-1.8 -5,-0.2 -1,-0.2 0.876 109.6 49.8 -66.5 -37.3 -22.4 48.7 13.3 9 10 A I H X S+ 0 0 40 -4,-1.8 4,-2.3 1,-0.2 5,-0.3 0.936 108.5 53.1 -66.0 -45.2 -22.2 52.4 12.7 10 11 A R H X S+ 0 0 61 -4,-2.5 4,-1.8 1,-0.2 -2,-0.2 0.899 109.5 48.7 -55.6 -45.4 -20.4 51.9 9.4 11 12 A R H < S+ 0 0 51 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.894 117.1 38.1 -65.9 -43.3 -23.2 49.5 8.1 12 13 A T H < S+ 0 0 93 -4,-1.8 4,-0.4 1,-0.1 -1,-0.2 0.768 116.5 51.6 -81.9 -25.0 -26.2 51.7 9.0 13 14 A L H >X S+ 0 0 9 -4,-2.3 3,-1.0 -5,-0.2 4,-0.9 0.889 94.0 71.0 -78.7 -39.5 -24.6 55.0 8.0 14 15 A L H >X S+ 0 0 49 -4,-1.8 4,-2.6 -5,-0.3 3,-1.3 0.873 97.5 46.9 -46.4 -54.2 -23.4 54.1 4.5 15 16 A P H 34 S+ 0 0 89 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.788 108.3 58.6 -63.4 -24.2 -26.8 54.0 2.8 16 17 A L H <4 S+ 0 0 91 -3,-1.0 -2,-0.2 -4,-0.4 -3,-0.1 0.655 121.3 22.1 -78.6 -16.2 -27.8 57.3 4.4 17 18 A I H X< S+ 0 0 0 -3,-1.3 3,-1.9 -4,-0.9 34,-0.3 0.610 85.8 117.7-125.8 -17.3 -24.9 59.2 2.9 18 19 A V T 3< S+ 0 0 69 -4,-2.6 34,-0.2 1,-0.2 3,-0.1 -0.255 84.6 16.4 -58.0 136.4 -23.6 57.4 -0.2 19 20 A G T 3 S+ 0 0 50 32,-3.0 -1,-0.2 1,-0.3 2,-0.2 0.328 93.9 127.2 85.6 -9.3 -23.9 59.4 -3.4 20 21 A K < - 0 0 42 -3,-1.9 31,-2.7 31,-0.1 2,-0.4 -0.578 52.4-135.7 -84.1 146.7 -24.5 62.7 -1.6 21 22 A T B -A 50 0A 38 29,-0.2 79,-2.2 -2,-0.2 2,-0.3 -0.849 16.6-120.5-106.0 136.0 -22.3 65.8 -2.5 22 23 A I E +B 99 0B 7 27,-2.7 26,-2.9 -2,-0.4 77,-0.3 -0.584 31.9 169.8 -78.3 128.4 -20.9 68.2 0.2 23 24 A E E - 0 0 125 75,-3.5 2,-0.3 1,-0.4 76,-0.2 0.705 67.1 -0.0-106.2 -32.9 -21.9 71.8 -0.1 24 25 A D E -B 98 0B 58 74,-1.5 74,-2.8 22,-0.1 2,-0.4 -0.991 52.6-150.9-156.7 154.6 -20.6 73.2 3.2 25 26 A V E -B 97 0B 8 -2,-0.3 2,-0.5 72,-0.2 72,-0.2 -0.984 16.4-166.6-132.2 119.2 -18.6 72.0 6.3 26 27 A R E -B 96 0B 137 70,-2.5 70,-2.5 -2,-0.4 2,-0.5 -0.919 1.0-164.2-113.2 130.9 -19.2 73.8 9.6 27 28 A I E +B 95 0B 36 -2,-0.5 68,-0.2 68,-0.2 67,-0.1 -0.954 17.4 171.7-119.9 122.7 -17.0 73.5 12.7 28 29 A F S S+ 0 0 105 66,-3.2 67,-0.2 -2,-0.5 -1,-0.1 0.452 81.6 36.0-105.4 -4.5 -18.0 74.5 16.2 29 30 A W > - 0 0 88 65,-0.9 3,-1.6 1,-0.1 4,-0.3 -0.663 66.9-169.0-151.5 87.3 -15.0 73.0 18.1 30 31 A P G > S+ 0 0 65 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 0.700 75.4 77.2 -47.6 -35.1 -11.7 73.3 16.1 31 32 A N G 3 S+ 0 0 103 1,-0.3 81,-0.0 84,-0.0 0, 0.0 0.771 85.0 64.6 -53.5 -28.9 -9.6 71.0 18.4 32 33 A I G < S+ 0 0 0 -3,-1.6 84,-1.9 83,-0.1 2,-0.6 0.826 85.3 83.8 -64.8 -31.4 -11.3 68.0 16.8 33 34 A I E < +e 116 0C 8 -3,-1.7 84,-0.1 -4,-0.3 6,-0.1 -0.642 49.9 165.3 -77.0 113.1 -9.7 68.8 13.5 34 35 A R E + 0 0 124 82,-2.5 83,-0.2 -2,-0.6 3,-0.2 0.744 52.3 61.3-101.5 -29.1 -6.2 67.3 13.5 35 36 A H E S+e 117 0C 57 81,-1.3 83,-2.5 1,-0.4 -1,-0.3 -0.908 105.8 23.7-158.9 125.9 -5.2 67.5 9.8 36 37 A P S S- 0 0 22 0, 0.0 -1,-0.4 0, 0.0 6,-0.2 0.602 89.2-143.9 -66.1 154.8 -5.0 69.8 8.1 37 38 A R S S+ 0 0 60 -2,-0.2 2,-0.5 -3,-0.2 -2,-0.1 0.882 81.4 77.6 -56.6 -43.2 -4.4 71.8 11.3 38 39 A D S >> S- 0 0 100 1,-0.2 4,-2.0 -4,-0.1 3,-0.6 -0.588 71.3-153.2 -73.3 117.2 -6.3 74.9 10.0 39 40 A S H 3> S+ 0 0 37 -2,-0.5 4,-2.1 1,-0.2 -1,-0.2 0.783 93.6 59.8 -63.1 -26.5 -10.0 74.2 10.2 40 41 A E H 3> S+ 0 0 62 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.873 107.0 45.4 -68.9 -36.9 -10.7 76.6 7.4 41 42 A A H <> S+ 0 0 42 -3,-0.6 4,-2.2 2,-0.2 -2,-0.2 0.894 110.2 55.2 -71.2 -40.9 -8.6 74.5 5.0 42 43 A F H X S+ 0 0 0 -4,-2.0 4,-0.7 -6,-0.2 -2,-0.2 0.910 112.2 43.5 -56.1 -47.2 -10.2 71.3 6.3 43 44 A A H >X S+ 0 0 16 -4,-2.1 4,-0.9 1,-0.2 3,-0.8 0.953 112.6 50.9 -66.1 -51.6 -13.6 72.7 5.4 44 45 A A H 3< S+ 0 0 67 -4,-2.2 3,-0.5 1,-0.2 -2,-0.2 0.849 103.6 57.3 -57.8 -40.5 -12.7 74.2 2.0 45 46 A R H 3< S+ 0 0 98 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.772 105.8 49.4 -67.7 -24.8 -11.1 71.0 0.6 46 47 A M H X< S+ 0 0 1 -3,-0.8 3,-2.1 -4,-0.7 -24,-0.3 0.688 81.8 110.0 -87.8 -17.5 -14.1 68.8 1.0 47 48 A I T 3< S+ 0 0 69 -4,-0.9 -24,-0.2 -3,-0.5 3,-0.1 -0.347 85.2 18.8 -58.2 131.3 -16.6 71.2 -0.6 48 49 A G T 3 S+ 0 0 49 -26,-2.9 2,-0.3 1,-0.3 -1,-0.3 0.332 95.5 119.9 90.7 -9.4 -17.8 69.7 -3.9 49 50 A Q < - 0 0 17 -3,-2.1 -27,-2.7 -27,-0.1 2,-0.4 -0.662 55.1-136.7 -90.5 148.6 -16.7 66.1 -3.3 50 51 A T B -A 21 0A 15 -2,-0.3 2,-0.5 -29,-0.2 -29,-0.2 -0.834 20.2-112.2-106.8 141.3 -19.2 63.3 -3.3 51 52 A V + 0 0 6 -31,-2.7 -32,-3.0 -2,-0.4 14,-0.2 -0.599 38.6 170.1 -72.0 119.2 -19.4 60.4 -0.7 52 53 A R - 0 0 148 12,-2.9 2,-0.3 -2,-0.5 13,-0.2 0.620 57.1 -24.2-105.5 -19.8 -18.4 57.2 -2.6 53 54 A G E -F 64 0C 11 11,-1.5 11,-2.5 -36,-0.1 2,-0.3 -0.990 46.7-129.5-176.5 176.8 -18.1 54.8 0.3 54 55 A L E +F 63 0C 5 -2,-0.3 2,-0.2 9,-0.2 9,-0.2 -0.922 26.4 171.6-150.9 119.0 -17.4 54.1 4.0 55 56 A E E -F 62 0C 101 7,-2.3 7,-3.3 -2,-0.3 2,-0.4 -0.723 20.9-134.2-122.4 171.7 -14.9 51.6 5.5 56 57 A R E -F 61 0C 46 5,-0.2 2,-0.4 -2,-0.2 5,-0.2 -0.975 14.4-178.5-129.8 143.8 -13.6 50.7 8.9 57 58 A R E > -F 60 0C 66 3,-2.1 3,-2.5 -2,-0.4 2,-0.2 -0.936 69.7 -45.5-141.0 111.8 -10.0 50.0 10.1 58 59 A G T 3 S- 0 0 0 -2,-0.4 111,-0.1 1,-0.3 -52,-0.1 -0.457 124.1 -24.6 63.4-128.8 -9.6 49.1 13.8 59 60 A K T 3 S+ 0 0 32 -2,-0.2 15,-0.5 -3,-0.1 -1,-0.3 0.320 119.6 102.9 -96.8 7.6 -11.8 51.6 15.7 60 61 A F E < -FG 57 73C 22 -3,-2.5 -3,-2.1 13,-0.1 2,-0.4 -0.649 61.4-144.3 -94.9 147.7 -11.6 54.2 12.9 61 62 A L E -FG 56 72C 0 11,-2.6 11,-2.5 -2,-0.3 2,-0.5 -0.864 11.6-156.8-104.2 141.3 -14.2 55.1 10.3 62 63 A K E -FG 55 71C 18 -7,-3.3 -7,-2.3 -2,-0.4 2,-0.5 -0.885 0.7-159.6-125.1 100.7 -12.9 56.0 6.8 63 64 A F E -FG 54 70C 6 7,-2.7 7,-2.7 -2,-0.5 2,-0.6 -0.675 12.8-149.8 -78.1 121.4 -15.2 58.1 4.7 64 65 A L E +FG 53 69C 33 -11,-2.5 -12,-2.9 -2,-0.5 -11,-1.5 -0.860 24.3 167.6 -98.8 117.8 -14.2 57.8 1.1 65 66 A L - 0 0 5 3,-2.6 -14,-0.1 -2,-0.6 -19,-0.0 0.006 52.2 -72.7-105.7-148.7 -14.9 60.8 -1.1 66 67 A D S S- 0 0 64 -2,-0.1 -15,-0.0 -14,-0.0 -17,-0.0 0.979 119.4 -8.0 -77.9 -57.7 -13.7 61.7 -4.6 67 68 A R S S+ 0 0 62 54,-0.1 54,-2.7 53,-0.1 55,-0.2 0.736 128.0 57.3-107.1 -35.6 -10.0 62.6 -4.0 68 69 A D E - H 0 120C 10 52,-0.3 -3,-2.6 -23,-0.1 2,-0.4 -0.470 60.9-145.6-100.3 169.6 -9.8 62.5 -0.2 69 70 A A E -GH 64 119C 1 50,-2.4 50,-1.8 -5,-0.2 2,-0.6 -0.998 14.6-146.2-130.5 129.6 -10.5 60.1 2.7 70 71 A L E -GH 63 118C 6 -7,-2.7 -7,-2.7 -2,-0.4 2,-0.6 -0.910 12.1-157.4-101.5 116.2 -11.8 61.5 6.0 71 72 A I E -GH 62 117C 1 46,-3.3 46,-2.4 -2,-0.6 2,-0.4 -0.855 14.5-175.8 -98.9 118.2 -10.4 59.4 8.9 72 73 A S E -GH 61 116C 0 -11,-2.5 -11,-2.6 -2,-0.6 2,-0.5 -0.956 15.3-169.6-123.8 128.9 -12.6 59.7 12.1 73 74 A H E -GH 60 115C 28 42,-2.1 42,-1.7 -2,-0.4 -13,-0.1 -0.970 7.2-163.6-116.0 121.0 -12.0 58.3 15.6 74 75 A L >> - 0 0 1 -15,-0.5 4,-2.2 -2,-0.5 3,-0.6 0.617 20.2-175.1 -78.9 -12.9 -15.0 58.5 18.0 75 76 A R T 34 - 0 0 114 1,-0.2 -1,-0.2 2,-0.2 39,-0.0 -0.325 63.4 -18.2 53.6-121.4 -12.9 57.9 21.1 76 77 A M T 34 S+ 0 0 102 -2,-0.1 -1,-0.2 1,-0.1 -2,-0.1 0.893 139.7 0.4 -86.5 -43.2 -15.2 57.7 24.1 77 78 A E T <4 S+ 0 0 97 -3,-0.6 33,-0.5 2,-0.0 -2,-0.2 0.287 80.8 135.9-135.6 15.9 -18.5 59.3 23.1 78 79 A G < + 0 0 6 -4,-2.2 2,-0.3 31,-0.2 31,-0.2 -0.371 28.6 178.5 -66.2 145.1 -18.5 60.5 19.6 79 80 A R E -C 108 0B 45 29,-2.6 29,-2.7 -2,-0.0 2,-0.3 -0.993 19.0-143.0-148.8 153.2 -21.6 59.7 17.5 80 81 A Y E +C 107 0B 31 -2,-0.3 2,-0.3 27,-0.2 27,-0.2 -0.885 18.5 170.2-118.4 148.6 -23.0 60.3 14.0 81 82 A A E -C 106 0B 37 25,-1.5 25,-3.0 -2,-0.3 2,-0.4 -0.985 23.1-140.0-153.6 148.5 -26.6 61.0 12.7 82 83 A V E +C 105 0B 41 -2,-0.3 2,-0.3 23,-0.2 23,-0.2 -0.938 38.8 139.9-113.3 133.6 -28.2 62.1 9.5 83 84 A A E -C 104 0B 26 21,-2.0 21,-2.0 -2,-0.4 2,-0.2 -0.956 52.6 -62.1-160.0 176.9 -31.1 64.6 9.5 84 85 A S E > -C 103 0B 42 -2,-0.3 3,-1.1 19,-0.2 19,-0.2 -0.479 33.3-140.1 -72.0 136.2 -32.7 67.6 7.8 85 86 A A T 3 S+ 0 0 45 17,-2.3 -1,-0.1 1,-0.2 18,-0.1 0.520 98.6 68.3 -73.0 -5.1 -30.7 70.8 7.8 86 87 A L T 3 S+ 0 0 163 16,-0.2 -1,-0.2 2,-0.1 17,-0.1 0.655 86.0 79.9 -88.4 -17.3 -33.9 72.7 8.5 87 88 A E S < S- 0 0 112 -3,-1.1 2,-0.1 1,-0.1 -4,-0.0 -0.530 91.8 -93.8 -90.3 156.7 -34.3 71.3 12.1 88 89 A P - 0 0 120 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.371 44.7-108.5 -68.6 148.4 -32.4 72.6 15.2 89 90 A L - 0 0 73 1,-0.1 3,-0.1 -4,-0.1 -4,-0.0 -0.375 29.4-114.6 -75.3 154.8 -29.2 70.8 16.2 90 91 A E > - 0 0 77 1,-0.2 3,-0.8 -2,-0.1 -1,-0.1 -0.492 47.4 -76.6 -85.1 158.2 -28.9 68.6 19.2 91 92 A P T 3 S+ 0 0 91 0, 0.0 -1,-0.2 0, 0.0 3,-0.1 -0.186 113.6 21.7 -55.8 146.6 -26.7 69.5 22.2 92 93 A H T 3 S+ 0 0 93 1,-0.2 17,-1.8 16,-0.1 2,-0.7 0.771 76.0 156.7 66.5 30.3 -22.9 69.0 21.8 93 94 A T E < + D 0 108B 15 -3,-0.8 15,-0.2 15,-0.2 -1,-0.2 -0.787 8.7 168.8 -87.1 116.0 -22.9 69.0 18.0 94 95 A H E + 0 0 15 13,-2.1 -66,-3.2 -2,-0.7 -65,-0.9 0.716 58.0 26.5-103.8 -23.7 -19.3 70.0 17.0 95 96 A V E -BD 27 107B 0 12,-1.3 12,-2.7 -68,-0.2 2,-0.4 -0.998 61.2-171.8-141.9 138.1 -19.0 69.3 13.3 96 97 A V E -BD 26 106B 4 -70,-2.5 -70,-2.5 -2,-0.3 2,-0.6 -0.993 11.3-158.1-135.5 130.9 -21.6 69.3 10.5 97 98 A F E -BD 25 105B 6 8,-2.8 8,-2.5 -2,-0.4 2,-0.5 -0.926 16.3-156.6-107.5 115.0 -21.4 68.3 6.8 98 99 A C E -BD 24 104B 17 -74,-2.8 -75,-3.5 -2,-0.6 -74,-1.5 -0.789 7.3-152.5 -95.5 129.2 -24.1 69.8 4.7 99 100 A F E > -B 22 0B 8 4,-2.6 3,-1.5 -2,-0.5 -77,-0.2 -0.563 26.6-112.3 -98.0 163.4 -25.1 68.1 1.5 100 101 A T T 3 S+ 0 0 84 -79,-2.2 -78,-0.1 1,-0.3 -1,-0.1 0.646 111.9 63.5 -67.8 -14.4 -26.6 69.6 -1.7 101 102 A D T 3 S- 0 0 89 -80,-0.2 -1,-0.3 2,-0.1 3,-0.1 0.337 119.7-102.1 -92.6 8.1 -29.9 67.8 -1.2 102 103 A G S < S+ 0 0 41 -3,-1.5 -17,-2.3 1,-0.3 -16,-0.2 0.432 88.5 112.9 89.9 -3.5 -30.7 69.7 2.1 103 104 A S E -C 84 0B 30 -19,-0.2 -4,-2.6 -18,-0.1 -1,-0.3 -0.502 48.1-158.9 -93.9 168.8 -29.7 66.8 4.4 104 105 A E E -CD 83 98B 15 -21,-2.0 -21,-2.0 -6,-0.2 2,-0.6 -0.998 19.8-133.1-153.2 150.7 -26.7 66.8 6.7 105 106 A L E -CD 82 97B 6 -8,-2.5 -8,-2.8 -2,-0.3 2,-0.4 -0.924 30.6-161.8-102.9 117.5 -24.3 64.5 8.6 106 107 A R E -CD 81 96B 5 -25,-3.0 -25,-1.5 -2,-0.6 2,-0.5 -0.846 8.8-155.2-107.7 138.7 -23.9 65.7 12.2 107 108 A Y E -CD 80 95B 1 -12,-2.7 -13,-2.1 -2,-0.4 -12,-1.3 -0.952 13.7-175.4-113.2 119.4 -21.1 64.7 14.6 108 109 A R E +CD 79 93B 81 -29,-2.7 -29,-2.6 -2,-0.5 -15,-0.2 -0.853 10.3 167.0-112.0 149.7 -21.8 64.9 18.4 109 110 A D > - 0 0 1 -17,-1.8 3,-1.2 -2,-0.3 -31,-0.2 -0.575 17.3-166.8-166.3 93.1 -19.2 64.3 21.2 110 111 A V T 3 S+ 0 0 73 -33,-0.5 -1,-0.1 1,-0.3 -18,-0.1 0.876 94.3 39.3 -49.6 -48.3 -20.0 65.3 24.8 111 112 A R T 3 S- 0 0 125 -19,-0.0 -1,-0.3 1,-0.0 -33,-0.0 0.530 99.5-135.6 -84.7 -5.1 -16.4 64.9 26.0 112 113 A K < + 0 0 80 -3,-1.2 -2,-0.1 -20,-0.1 -37,-0.1 0.833 64.3 127.1 55.1 39.2 -14.8 66.4 22.9 113 114 A F + 0 0 83 -39,-0.2 -38,-0.1 2,-0.0 -1,-0.1 0.697 37.1 108.0 -96.6 -22.2 -12.1 63.7 22.6 114 115 A G - 0 0 1 -40,-0.3 2,-0.3 1,-0.1 -40,-0.2 -0.017 52.3-150.1 -56.6 160.8 -12.7 62.6 19.0 115 116 A T E - H 0 73C 4 -42,-1.7 -42,-2.1 -82,-0.0 2,-0.4 -0.949 9.2-160.1-135.2 154.1 -10.4 63.4 16.0 116 117 A M E -eH 33 72C 0 -84,-1.9 -82,-2.5 -2,-0.3 -81,-1.3 -0.994 8.3-178.5-137.4 127.8 -10.6 63.9 12.2 117 118 A H E -eH 35 71C 26 -46,-2.4 -46,-3.3 -2,-0.4 2,-0.5 -0.984 9.0-159.8-124.9 136.3 -7.8 63.7 9.7 118 119 A V E + H 0 70C 0 -83,-2.5 2,-0.3 -2,-0.4 -48,-0.2 -0.975 22.2 154.0-120.5 124.5 -8.1 64.3 5.9 119 120 A Y E - H 0 69C 11 -50,-1.8 -50,-2.4 -2,-0.5 2,-0.1 -0.922 52.1 -83.4-139.4 164.6 -5.6 63.0 3.4 120 121 A A E >> - H 0 68C 50 -2,-0.3 3,-2.0 -52,-0.2 4,-1.4 -0.460 52.0-109.4 -66.6 144.2 -5.6 62.1 -0.3 121 122 A K H 3> S+ 0 0 83 -54,-2.7 4,-0.5 1,-0.3 3,-0.5 0.855 115.8 51.5 -41.8 -52.3 -7.0 58.5 -0.6 122 123 A E H 34 S+ 0 0 104 -55,-0.2 -1,-0.3 1,-0.2 -54,-0.1 0.620 112.5 46.4 -66.6 -14.1 -3.6 56.9 -1.6 123 124 A E H X> S+ 0 0 34 -3,-2.0 3,-1.4 2,-0.1 4,-0.9 0.678 87.9 85.0-101.9 -20.3 -1.8 58.5 1.4 124 125 A A H >< S+ 0 0 0 -4,-1.4 3,-0.9 -3,-0.5 6,-0.4 0.872 89.3 48.8 -49.6 -51.3 -4.2 57.7 4.2 125 126 A D T 3< S+ 0 0 99 -4,-0.5 -1,-0.3 1,-0.2 -2,-0.1 0.626 113.2 49.4 -68.8 -12.0 -3.0 54.2 5.0 126 127 A R T <4 S+ 0 0 76 -3,-1.4 -1,-0.2 2,-0.1 -2,-0.2 0.543 104.8 63.9-103.5 -9.6 0.6 55.3 5.1 127 128 A R S XX S- 0 0 110 -4,-0.9 4,-2.2 -3,-0.9 3,-0.7 -0.664 91.7 -54.2-110.0 165.4 0.2 58.4 7.4 128 129 A P T 34 S+ 0 0 77 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 -0.437 110.3 31.4 -73.5 159.3 -0.9 58.6 11.0 129 130 A P T 34 S+ 0 0 36 0, 0.0 3,-0.2 0, 0.0 -4,-0.1 -0.998 131.8 34.5 -84.6 -3.6 -3.2 57.7 12.7 130 131 A L T X4 S+ 0 0 8 -3,-0.7 3,-1.8 -6,-0.4 -5,-0.1 0.790 95.5 89.4 -79.1 -28.9 -3.7 54.6 10.5 131 132 A A T 3< S+ 0 0 51 -4,-2.2 -1,-0.2 -7,-0.3 -4,-0.1 0.808 93.4 32.2 -34.5 -62.2 -0.0 54.0 9.7 132 133 A E T 3 S+ 0 0 87 -3,-0.2 -1,-0.3 -5,-0.0 2,-0.2 0.011 84.3 135.5 -97.2 31.7 1.1 51.7 12.5 133 134 A L < - 0 0 25 -3,-1.8 33,-0.3 1,-0.1 36,-0.1 -0.515 51.3-122.1 -79.4 145.1 -2.2 49.8 13.2 134 135 A G - 0 0 5 31,-3.1 34,-0.2 -2,-0.2 33,-0.2 -0.086 44.7 -68.1 -73.8 179.5 -2.1 46.0 13.8 135 136 A P - 0 0 36 0, 0.0 34,-2.1 0, 0.0 -1,-0.2 -0.208 53.9 -94.4 -69.9 161.0 -4.1 43.5 11.7 136 137 A E > - 0 0 30 32,-0.2 3,-1.6 1,-0.1 6,-0.5 -0.606 29.7-137.1 -74.5 129.9 -7.8 43.1 11.6 137 138 A P T 3 S+ 0 0 2 0, 0.0 -1,-0.1 0, 0.0 33,-0.1 0.766 101.9 55.1 -59.6 -28.8 -8.9 40.4 14.1 138 139 A L T 3 S+ 0 0 88 72,-0.1 -2,-0.1 3,-0.0 69,-0.0 0.158 98.6 84.6 -92.5 20.0 -11.4 38.9 11.7 139 140 A S S X S- 0 0 37 -3,-1.6 3,-2.4 1,-0.1 0, 0.0 -0.886 89.1-112.5-124.0 154.9 -8.8 38.4 9.0 140 141 A P T 3 S+ 0 0 133 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.717 110.4 74.8 -52.6 -22.4 -6.2 35.8 8.1 141 142 A A T 3 S+ 0 0 61 -5,-0.1 2,-0.6 1,-0.1 5,-0.1 0.794 86.6 68.2 -63.3 -29.2 -3.5 38.4 9.0 142 143 A F < + 0 0 6 -3,-2.4 -1,-0.1 -6,-0.5 26,-0.1 -0.847 68.3 144.9 -96.9 119.7 -4.3 37.8 12.7 143 144 A S > - 0 0 40 -2,-0.6 4,-2.0 1,-0.1 3,-0.2 -0.897 64.4 -94.4-144.6 171.7 -3.3 34.4 14.0 144 145 A P H > S+ 0 0 49 0, 0.0 4,-3.8 0, 0.0 5,-0.2 0.910 122.7 58.9 -56.0 -41.1 -1.9 32.7 17.1 145 146 A A H > S+ 0 0 67 1,-0.2 4,-3.0 2,-0.2 5,-0.2 0.906 105.4 47.0 -53.5 -48.5 1.6 33.1 15.7 146 147 A V H > S+ 0 0 34 -3,-0.2 4,-1.5 2,-0.2 -1,-0.2 0.914 115.3 46.4 -61.9 -43.2 1.2 36.9 15.4 147 148 A L H X S+ 0 0 2 -4,-2.0 4,-2.7 1,-0.2 -2,-0.2 0.943 114.0 48.1 -64.3 -47.3 -0.1 37.0 19.0 148 149 A A H X S+ 0 0 31 -4,-3.8 4,-2.8 1,-0.2 -2,-0.2 0.915 105.6 58.2 -59.3 -46.1 2.7 34.7 20.2 149 150 A E H < S+ 0 0 69 -4,-3.0 -1,-0.2 1,-0.2 -2,-0.2 0.873 115.1 36.4 -52.8 -42.1 5.4 36.7 18.5 150 151 A R H < S+ 0 0 95 -4,-1.5 3,-0.5 -3,-0.2 -1,-0.2 0.847 116.9 53.4 -80.6 -35.9 4.4 39.9 20.4 151 152 A A H >< S+ 0 0 2 -4,-2.7 2,-3.0 1,-0.3 3,-1.8 0.983 103.5 54.0 -62.1 -60.4 3.5 38.0 23.6 152 153 A V T 3< S+ 0 0 80 -4,-2.8 -1,-0.3 1,-0.3 40,-0.1 -0.317 107.2 55.5 -74.2 59.6 6.8 36.2 24.0 153 154 A K T 3 S+ 0 0 81 -2,-3.0 2,-0.3 -3,-0.5 -1,-0.3 0.261 98.1 60.7-168.8 2.6 8.7 39.5 23.8 154 155 A T < - 0 0 39 -3,-1.8 -1,-0.3 2,-0.1 38,-0.3 -0.900 56.6-150.2-136.7 165.5 7.2 41.7 26.5 155 156 A K + 0 0 109 -2,-0.3 3,-0.1 36,-0.1 -1,-0.1 0.503 64.7 106.3-112.3 -11.0 6.9 41.7 30.3 156 157 A R S S- 0 0 82 34,-0.2 35,-2.8 1,-0.1 36,-0.3 -0.156 81.2 -78.6 -67.8 164.4 3.6 43.6 30.6 157 158 A S B > -I 190 0D 22 33,-0.3 4,-1.6 34,-0.1 31,-0.1 -0.125 36.1-116.3 -60.1 158.9 0.3 42.1 31.4 158 159 A V H > S+ 0 0 0 31,-2.1 4,-1.6 29,-0.4 30,-0.1 0.762 115.5 57.0 -70.0 -25.6 -1.8 40.2 28.8 159 160 A K H > S+ 0 0 0 28,-1.4 4,-1.5 30,-0.2 -1,-0.2 0.885 105.4 50.7 -72.1 -37.6 -4.5 42.9 29.0 160 161 A A H > S+ 0 0 19 27,-0.3 4,-0.6 1,-0.2 -2,-0.2 0.888 108.0 53.6 -65.7 -38.2 -2.1 45.6 28.2 161 162 A L H >< S+ 0 0 3 -4,-1.6 3,-0.7 1,-0.2 6,-0.2 0.911 110.1 46.8 -61.4 -43.9 -0.9 43.6 25.2 162 163 A L H 3< S+ 0 0 0 -4,-1.6 9,-0.3 1,-0.2 -1,-0.2 0.726 107.3 55.4 -71.8 -26.4 -4.5 43.3 23.9 163 164 A L H 3< S+ 0 0 33 -4,-1.5 2,-0.9 -3,-0.1 -1,-0.2 0.574 84.6 101.2 -82.2 -9.9 -5.3 47.0 24.3 164 165 A D XX - 0 0 39 -3,-0.7 3,-2.1 -4,-0.6 4,-1.3 -0.660 63.0-156.8 -80.6 104.3 -2.3 47.9 22.2 165 166 A Q T 34 S+ 0 0 43 -2,-0.9 -31,-3.1 1,-0.3 -1,-0.2 0.657 88.8 64.4 -57.1 -17.4 -3.7 48.7 18.7 166 167 A T T 34 S+ 0 0 59 -33,-0.3 -1,-0.3 1,-0.1 3,-0.2 0.711 103.3 48.4 -78.9 -20.3 -0.3 47.9 17.1 167 168 A V T <4 S- 0 0 8 -3,-2.1 2,-0.3 1,-0.4 -2,-0.2 0.926 137.6 -16.6 -80.6 -52.6 -0.6 44.3 18.1 168 169 A V S < S- 0 0 0 -4,-1.3 2,-0.4 -34,-0.2 -1,-0.4 -0.967 74.3-124.1-153.4 140.6 -4.2 43.8 16.9 169 170 A A S S+ 0 0 0 -34,-2.1 -111,-0.3 -2,-0.3 -4,-0.1 -0.782 78.3 30.9 -99.5 132.1 -6.7 46.5 16.0 170 171 A G S S+ 0 0 0 -2,-0.4 -167,-2.3 1,-0.3 2,-0.4 0.203 74.1 120.9 121.3 -20.0 -10.2 46.9 17.5 171 172 A F + 0 0 0 -3,-0.3 -1,-0.3 -9,-0.3 2,-0.2 -0.646 30.0 168.7 -87.6 135.3 -10.2 45.7 21.1 172 173 A G > - 0 0 3 -2,-0.4 4,-2.0 0, 0.0 5,-0.3 -0.523 53.2 -66.5-124.1-167.3 -11.1 47.9 24.0 173 174 A N H > S+ 0 0 15 1,-0.2 4,-1.6 2,-0.2 5,-0.2 0.846 126.4 48.1 -54.3 -42.4 -11.9 47.5 27.7 174 175 A I H > S+ 0 0 30 1,-0.2 4,-2.0 2,-0.2 54,-0.2 0.964 117.2 37.5 -67.9 -52.1 -15.2 45.5 27.2 175 176 A Y H > S+ 0 0 0 2,-0.2 4,-1.8 1,-0.2 -2,-0.2 0.702 113.5 55.8 -77.5 -18.2 -14.0 42.9 24.7 176 177 A V H X S+ 0 0 0 -4,-2.0 4,-2.1 2,-0.2 -1,-0.2 0.930 111.7 44.2 -75.1 -45.5 -10.6 42.4 26.2 177 178 A D H X S+ 0 0 1 -4,-1.6 4,-1.4 -5,-0.3 -2,-0.2 0.907 116.7 46.7 -63.3 -41.9 -12.1 41.6 29.6 178 179 A E H X S+ 0 0 0 -4,-2.0 4,-2.1 2,-0.2 -1,-0.2 0.877 111.6 50.2 -68.9 -39.1 -14.7 39.3 27.9 179 180 A S H X S+ 0 0 0 -4,-1.8 4,-1.6 1,-0.2 -2,-0.2 0.895 109.5 51.2 -66.7 -40.6 -12.2 37.5 25.7 180 181 A L H X>S+ 0 0 0 -4,-2.1 5,-2.9 2,-0.2 4,-0.7 0.854 110.2 49.5 -66.3 -34.5 -9.9 36.8 28.6 181 182 A F H ><5S+ 0 0 13 -4,-1.4 3,-1.0 3,-0.2 -2,-0.2 0.953 110.4 48.8 -67.8 -51.1 -12.7 35.3 30.7 182 183 A R H 3<5S+ 0 0 39 -4,-2.1 -2,-0.2 1,-0.3 -1,-0.2 0.798 115.2 45.8 -59.8 -29.0 -13.9 33.0 27.9 183 184 A A H 3<5S- 0 0 4 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.585 113.4-122.8 -88.7 -13.4 -10.3 31.9 27.4 184 185 A G T <<5 + 0 0 21 -3,-1.0 76,-1.3 -4,-0.7 2,-0.4 0.905 62.3 135.9 72.9 46.2 -9.9 31.4 31.1 185 186 A I < - 0 0 1 -5,-2.9 -1,-0.2 74,-0.2 -2,-0.1 -0.987 56.6-119.0-130.2 129.2 -6.9 33.8 31.7 186 187 A L > - 0 0 58 -2,-0.4 3,-1.2 1,-0.1 -28,-0.3 -0.435 21.1-137.0 -64.8 131.6 -6.3 36.3 34.5 187 188 A P T 3 S+ 0 0 5 0, 0.0 -28,-1.4 0, 0.0 -29,-0.4 0.841 96.7 55.5 -58.5 -36.8 -6.0 39.9 33.0 188 189 A G T 3 S+ 0 0 46 -31,-0.1 3,-0.1 -30,-0.1 60,-0.1 0.517 81.4 108.9 -79.7 -4.1 -3.1 40.9 35.2 189 190 A R S < S- 0 0 50 -3,-1.2 -31,-2.1 1,-0.1 -30,-0.2 -0.410 81.5 -87.9 -78.0 150.8 -0.7 38.1 34.4 190 191 A P B > -I 157 0D 67 0, 0.0 3,-1.9 0, 0.0 4,-0.4 -0.264 27.1-138.3 -54.0 130.2 2.6 38.5 32.4 191 192 A A G > S+ 0 0 1 -35,-2.8 3,-0.7 1,-0.3 -34,-0.1 0.777 104.7 59.8 -62.0 -25.9 1.9 38.2 28.6 192 193 A A G 3 S+ 0 0 59 -36,-0.3 -1,-0.3 -38,-0.3 -37,-0.1 0.517 93.9 64.8 -80.8 -5.6 5.2 36.2 28.5 193 194 A S G < S+ 0 0 54 -3,-1.9 2,-0.2 -38,-0.1 -1,-0.2 0.572 76.0 109.3 -92.2 -10.9 3.9 33.6 30.9 194 195 A L < - 0 0 17 -3,-0.7 -9,-0.0 -4,-0.4 -3,-0.0 -0.475 64.0-136.5 -70.5 131.8 1.2 32.4 28.6 195 196 A S > - 0 0 58 -2,-0.2 4,-2.1 1,-0.1 5,-0.1 -0.135 26.4-100.7 -77.6 178.9 1.8 28.9 27.1 196 197 A S H > S+ 0 0 86 2,-0.2 4,-1.8 1,-0.2 5,-0.2 0.858 123.7 51.6 -69.9 -36.2 1.2 27.9 23.5 197 198 A K H > S+ 0 0 75 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.875 110.0 49.7 -67.8 -38.7 -2.1 26.2 24.3 198 199 A E H > S+ 0 0 45 2,-0.2 4,-3.1 1,-0.2 5,-0.2 0.944 108.3 51.7 -65.4 -49.4 -3.3 29.4 26.1 199 200 A I H X S+ 0 0 16 -4,-2.1 4,-2.7 1,-0.2 5,-0.2 0.910 111.4 47.1 -55.3 -45.7 -2.3 31.7 23.2 200 201 A E H X S+ 0 0 47 -4,-1.8 4,-2.3 1,-0.2 -1,-0.2 0.921 113.1 49.6 -62.2 -43.5 -4.2 29.6 20.7 201 202 A R H X S+ 0 0 117 -4,-1.9 4,-2.2 2,-0.2 -2,-0.2 0.898 111.4 48.7 -61.1 -43.3 -7.2 29.5 23.1 202 203 A L H X S+ 0 0 0 -4,-3.1 4,-2.6 2,-0.2 -2,-0.2 0.927 110.1 50.8 -64.5 -45.3 -7.1 33.3 23.5 203 204 A H H X S+ 0 0 33 -4,-2.7 4,-2.1 -5,-0.2 -2,-0.2 0.916 110.7 50.9 -57.6 -43.5 -6.9 33.8 19.7 204 205 A E H X S+ 0 0 64 -4,-2.3 4,-1.9 1,-0.2 -1,-0.2 0.903 113.3 43.1 -61.6 -44.6 -9.9 31.5 19.3 205 206 A E H X S+ 0 0 36 -4,-2.2 4,-2.5 2,-0.2 5,-0.2 0.820 110.3 56.2 -73.1 -32.2 -12.0 33.4 21.9 206 207 A M H X S+ 0 0 0 -4,-2.6 4,-2.3 2,-0.2 5,-0.3 0.953 111.1 43.7 -64.0 -48.3 -11.0 36.8 20.6 207 208 A V H X S+ 0 0 45 -4,-2.1 4,-2.0 -5,-0.2 -2,-0.2 0.917 116.2 47.3 -62.4 -44.9 -12.2 36.0 17.1 208 209 A A H X S+ 0 0 33 -4,-1.9 4,-2.3 -5,-0.2 -1,-0.2 0.882 113.3 48.1 -65.5 -40.5 -15.4 34.4 18.4 209 210 A T H X S+ 0 0 0 -4,-2.5 4,-2.3 2,-0.2 -2,-0.2 0.956 115.0 42.6 -66.5 -51.7 -16.3 37.2 20.8 210 211 A I H X S+ 0 0 0 -4,-2.3 4,-2.0 -5,-0.2 -1,-0.2 0.876 115.2 53.1 -63.6 -35.7 -15.7 40.1 18.3 211 212 A G H X S+ 0 0 28 -4,-2.0 4,-1.5 -5,-0.3 -1,-0.2 0.915 111.5 43.0 -66.0 -44.3 -17.5 38.0 15.7 212 213 A E H X S+ 0 0 86 -4,-2.3 4,-1.4 2,-0.2 -2,-0.2 0.845 111.5 55.9 -69.6 -36.4 -20.6 37.4 17.8 213 214 A A H <>S+ 0 0 0 -4,-2.3 5,-2.7 2,-0.2 4,-0.2 0.904 105.8 50.3 -63.3 -43.2 -20.6 41.0 19.0 214 215 A V H ><5S+ 0 0 43 -4,-2.0 3,-1.6 1,-0.2 -1,-0.2 0.929 107.9 54.6 -61.4 -42.4 -20.8 42.4 15.5 215 216 A M H 3<5S+ 0 0 87 -4,-1.5 -1,-0.2 1,-0.3 -2,-0.2 0.823 108.7 48.0 -60.5 -33.4 -23.7 40.0 14.7 216 217 A K T 3<5S- 0 0 66 -4,-1.4 -1,-0.3 -3,-0.2 -2,-0.2 0.309 119.7-106.3 -91.6 8.4 -25.7 41.4 17.7 217 218 A G T < 5 - 0 0 39 -3,-1.6 -3,-0.2 -4,-0.2 -2,-0.1 0.794 63.1 -77.3 74.3 28.6 -25.1 45.1 16.8 218 219 A G < 0 0 3 -5,-2.7 4,-0.4 -6,-0.1 -215,-0.0 -0.112 360.0 360.0 76.5-176.7 -22.6 45.8 19.5 219 220 A S 0 0 54 2,-0.2 -1,-0.1 3,-0.1 -2,-0.1 -0.914 360.0 360.0-107.4 360.0 -23.2 46.4 23.2 220 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 221 235 A F > 0 0 12 0, 0.0 3,-2.6 0, 0.0 -2,-0.2 0.000 360.0 360.0 360.0 -13.4 -24.7 42.0 23.0 222 236 A Q G > + 0 0 96 -4,-0.4 3,-1.0 1,-0.3 -3,-0.1 0.753 360.0 61.5 -59.0 -22.7 -24.7 43.5 26.5 223 237 A H G 3 S+ 0 0 142 1,-0.2 -1,-0.3 3,-0.0 -4,-0.0 0.566 100.4 55.6 -79.2 -8.0 -27.0 40.6 27.5 224 238 A H G < S+ 0 0 106 -3,-2.6 2,-0.4 -11,-0.0 -1,-0.2 0.084 78.4 124.9-110.7 21.4 -24.2 38.2 26.7 225 239 A L < - 0 0 17 -3,-1.0 -3,-0.0 1,-0.1 -51,-0.0 -0.703 36.7-174.5 -86.7 128.5 -21.6 39.8 28.9 226 240 A Y S S- 0 0 78 -2,-0.4 10,-0.3 9,-0.1 -1,-0.1 0.841 79.1 -4.3 -88.6 -37.6 -19.9 37.4 31.4 227 241 A V S > S+ 0 0 0 -53,-0.1 3,-2.5 26,-0.1 27,-0.2 0.735 91.5 107.4-127.4 -40.4 -17.8 40.0 33.4 228 242 A Y T 3 S- 0 0 81 1,-0.3 -3,-0.1 -54,-0.2 -54,-0.1 -0.239 103.9 -6.5 -53.1 122.3 -17.8 43.6 32.2 229 243 A G T 3 S+ 0 0 45 1,-0.1 -1,-0.3 -2,-0.0 15,-0.1 0.576 106.6 106.5 69.5 11.5 -19.8 45.7 34.6 230 244 A R X + 0 0 46 -3,-2.5 3,-2.4 13,-0.1 12,-0.4 0.167 40.1 150.1-106.2 18.2 -21.0 42.7 36.6 231 245 A Q T 3 S+ 0 0 76 1,-0.3 12,-0.2 -4,-0.2 22,-0.0 -0.228 70.1 20.4 -53.7 133.7 -18.8 43.2 39.7 232 246 A G T 3 S+ 0 0 60 10,-3.0 -1,-0.3 1,-0.3 11,-0.1 0.249 104.1 105.4 91.1 -13.6 -20.5 41.9 42.9 233 247 A N S < S- 0 0 79 -3,-2.4 9,-3.0 -6,-0.1 -1,-0.3 -0.681 80.3 -92.6 -98.9 154.5 -22.8 39.6 40.8 234 248 A P B -J 241 0E 76 0, 0.0 6,-0.2 0, 0.0 -1,-0.1 -0.358 42.8-103.8 -68.1 142.0 -22.4 35.8 40.5 235 249 A C > - 0 0 8 5,-1.6 4,-1.0 1,-0.1 -8,-0.1 -0.382 22.4-134.1 -61.9 140.8 -20.5 34.3 37.6 236 250 A K T 4 S+ 0 0 109 -10,-0.3 -1,-0.1 1,-0.2 -9,-0.0 0.702 103.5 39.5 -70.4 -19.5 -22.8 32.9 35.0 237 251 A R T 4 S+ 0 0 198 3,-0.1 -1,-0.2 -11,-0.1 -2,-0.0 0.798 135.9 7.0-101.2 -35.9 -20.7 29.8 34.8 238 252 A C T 4 S- 0 0 40 2,-0.2 -2,-0.1 0, 0.0 0, 0.0 0.516 87.4-122.0-125.9 -11.4 -19.6 29.0 38.4 239 253 A G < + 0 0 41 -4,-1.0 -3,-0.1 1,-0.3 3,-0.1 0.327 61.4 140.7 86.5 -10.2 -21.5 31.4 40.7 240 254 A T - 0 0 37 -6,-0.2 -5,-1.6 1,-0.1 -1,-0.3 -0.447 65.0 -96.0 -66.4 138.3 -18.4 33.0 42.3 241 255 A P B -J 234 0E 80 0, 0.0 2,-0.2 0, 0.0 -1,-0.1 -0.314 39.6-118.2 -58.8 131.9 -18.9 36.7 42.8 242 256 A I - 0 0 4 -9,-3.0 -10,-3.0 -12,-0.4 2,-0.3 -0.481 32.4-149.7 -70.8 139.9 -17.3 38.8 39.9 243 257 A E E -K 254 0F 86 11,-2.5 11,-1.9 -12,-0.2 2,-0.4 -0.769 8.4-154.3-113.6 158.9 -14.5 41.1 41.0 244 258 A K E +K 253 0F 106 -2,-0.3 9,-0.2 9,-0.2 2,-0.2 -0.998 25.3 142.6-135.7 132.1 -13.2 44.4 39.8 245 259 A T E -K 252 0F 61 7,-2.2 7,-2.7 -2,-0.4 2,-0.5 -0.628 48.9 -81.8-142.0-160.5 -9.7 46.0 40.2 246 260 A V E +K 251 0F 110 5,-0.2 2,-0.4 -2,-0.2 5,-0.2 -0.980 41.9 167.0-122.8 126.4 -7.3 48.1 38.2 247 261 A V E > S-K 250 0F 23 3,-2.3 3,-0.8 -2,-0.5 -59,-0.0 -0.993 71.8 -0.8-139.8 129.7 -4.9 46.7 35.5 248 262 A A T 3 S- 0 0 55 -2,-0.4 -1,-0.1 1,-0.2 3,-0.1 0.892 132.3 -57.6 58.9 38.5 -2.9 48.6 32.9 249 263 A G T 3 S+ 0 0 67 1,-0.2 2,-0.3 -3,-0.1 -1,-0.2 0.707 117.8 92.7 66.9 24.6 -4.5 51.8 34.4 250 264 A R E < S-K 247 0F 100 -3,-0.8 -3,-2.3 -77,-0.0 -1,-0.2 -0.982 84.8 -82.8-147.8 158.5 -8.1 50.8 33.9 251 265 A G E -K 246 0F 24 -2,-0.3 2,-0.4 -5,-0.2 -5,-0.2 -0.383 49.1-167.2 -58.7 129.6 -11.1 49.2 35.4 252 266 A T E -K 245 0F 0 -7,-2.7 -7,-2.2 -2,-0.1 2,-0.4 -0.987 8.7-161.0-130.2 129.5 -10.8 45.4 35.0 253 267 A H E +K 244 0F 5 -2,-0.4 2,-0.3 -9,-0.2 -9,-0.2 -0.877 24.1 141.1-111.7 139.8 -13.5 42.7 35.5 254 268 A Y E -K 243 0F 36 -11,-1.9 -11,-2.5 -2,-0.4 -68,-0.1 -0.989 47.2-111.7-166.3 165.2 -12.9 39.0 36.0 255 269 A C > - 0 0 0 -2,-0.3 4,-1.9 -13,-0.2 -13,-0.1 -0.944 20.6-149.9-108.9 120.4 -13.9 35.8 37.9 256 270 A P T 4 S+ 0 0 55 0, 0.0 -1,-0.1 0, 0.0 -70,-0.1 0.680 95.1 42.1 -63.0 -18.7 -11.2 34.5 40.3 257 271 A R T 4 S+ 0 0 185 1,-0.1 -2,-0.0 -17,-0.0 0, 0.0 0.892 115.7 42.3 -94.2 -49.9 -12.2 30.9 39.8 258 272 A C T 4 S+ 0 0 36 -18,-0.1 2,-0.5 1,-0.1 -1,-0.1 0.806 111.6 63.0 -67.6 -29.9 -12.8 30.6 36.0 259 273 A Q < 0 0 2 -4,-1.9 -74,-0.2 1,-0.1 -78,-0.1 -0.859 360.0 360.0-104.0 129.0 -9.7 32.6 35.2 260 274 A R 0 0 80 -76,-1.3 -75,-0.2 -2,-0.5 -1,-0.1 0.319 360.0 360.0-130.8 360.0 -6.2 31.4 36.2