==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-MAR-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 21-DEC-09 3L5F . COMPND 2 MOLECULE: BETA-SECRETASE 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.STRICKLAND,Z.ZHU . 779 2 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 33081.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 516 66.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 36 4.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 224 28.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 86 11.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 81 10.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 62 8.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 7 0 1 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 7 5 5 6 8 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 2 0 4 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 58 A G 0 0 59 0, 0.0 3,-0.4 0, 0.0 183,-0.1 0.000 360.0 360.0 360.0 104.9 36.7 -15.1 29.5 2 59 A S + 0 0 106 181,-0.3 3,-0.2 1,-0.2 182,-0.1 0.429 360.0 64.4 -91.3 0.3 33.9 -17.2 28.1 3 60 A F >> + 0 0 60 1,-0.2 3,-1.9 2,-0.1 4,-1.1 -0.287 53.7 149.0-119.1 50.2 32.6 -14.8 25.4 4 61 A V T 34 + 0 0 114 -3,-0.4 3,-0.2 1,-0.3 -1,-0.2 0.787 66.6 64.3 -53.0 -31.8 35.6 -14.6 23.1 5 62 A E T 34 S+ 0 0 94 1,-0.2 -1,-0.3 -3,-0.2 -2,-0.1 0.766 111.7 36.6 -68.0 -20.7 33.5 -14.1 20.0 6 63 A M T X4 S+ 0 0 12 -3,-1.9 3,-1.3 171,-0.0 172,-0.7 0.567 89.2 109.2-106.4 -11.7 32.3 -10.8 21.4 7 64 A V T 3< S+ 0 0 35 -4,-1.1 170,-0.1 1,-0.3 87,-0.0 -0.441 89.0 11.5 -67.3 137.0 35.5 -9.5 23.2 8 65 A D T 3 S+ 0 0 90 -2,-0.1 -1,-0.3 149,-0.1 169,-0.2 0.765 84.8 132.4 68.6 26.8 37.1 -6.6 21.4 9 66 A N < + 0 0 18 -3,-1.3 12,-0.6 84,-0.1 2,-0.3 0.398 49.4 85.5 -89.2 2.6 34.1 -6.0 19.2 10 67 A L E -AB 20 176A 0 166,-2.4 165,-2.9 10,-0.1 166,-0.8 -0.768 49.9-179.0-107.4 152.4 33.9 -2.2 19.8 11 68 A R E +A 19 0A 73 8,-1.7 8,-2.9 -2,-0.3 2,-0.3 -0.934 38.2 60.2-137.5 159.4 35.8 0.7 18.2 12 69 A G E -A 18 0A 7 158,-0.5 2,-0.3 161,-0.3 6,-0.3 -0.822 62.7-100.9 124.5-163.1 35.7 4.4 18.9 13 70 A K E > -A 17 0A 66 4,-1.3 4,-2.1 -2,-0.3 3,-0.5 -0.969 35.9 -92.2-161.0 164.7 36.4 6.8 21.7 14 71 A S T 4 S+ 0 0 10 -2,-0.3 325,-0.2 1,-0.2 4,-0.1 0.860 117.8 50.2 -55.3 -40.9 34.6 8.9 24.3 15 72 A G T 4 S+ 0 0 26 1,-0.2 -1,-0.2 2,-0.1 221,-0.1 0.810 124.6 24.7 -70.9 -32.2 34.2 12.1 22.3 16 73 A Q T 4 S- 0 0 55 -3,-0.5 -1,-0.2 1,-0.2 -2,-0.2 0.461 115.9-106.7-111.7 -3.3 32.8 10.5 19.1 17 74 A G E < -A 13 0A 9 -4,-2.1 -4,-1.3 17,-0.1 2,-0.4 0.027 23.4 -89.4 97.2 155.5 31.2 7.4 20.6 18 75 A Y E -A 12 0A 3 17,-0.3 17,-3.1 215,-0.3 2,-0.3 -0.884 45.1-169.5-102.9 134.6 31.8 3.6 20.7 19 76 A Y E -AC 11 34A 4 -8,-2.9 -8,-1.7 -2,-0.4 2,-0.3 -0.877 15.7-153.0-131.2 158.7 30.3 1.5 18.0 20 77 A V E -AC 10 33A 1 13,-2.5 13,-2.9 -2,-0.3 2,-0.3 -0.913 30.4-107.7-126.1 149.1 29.7 -2.1 17.1 21 78 A E E + C 0 32A 61 -12,-0.6 72,-0.4 -2,-0.3 2,-0.3 -0.619 43.7 170.2 -79.9 137.5 29.3 -3.7 13.6 22 79 A M E - C 0 31A 0 9,-2.9 9,-2.5 -2,-0.3 2,-0.4 -0.906 23.6-140.0-137.3 164.8 25.8 -4.8 12.7 23 80 A T E -DC 90 30A 16 67,-2.5 67,-2.0 -2,-0.3 2,-0.4 -0.981 14.4-169.7-128.4 145.6 24.0 -6.0 9.6 24 81 A V E > +DC 89 29A 1 5,-2.1 5,-2.2 -2,-0.4 65,-0.2 -0.989 45.5 5.0-132.3 141.5 20.6 -5.1 8.4 25 82 A G T 5S- 0 0 5 63,-1.9 4,-0.1 -2,-0.4 36,-0.1 -0.014 88.0 -44.8 84.1 175.3 18.5 -6.6 5.6 26 83 A S T 5S+ 0 0 30 2,-0.1 36,-2.6 1,-0.1 37,-0.3 -0.982 130.6 29.0-132.4 115.8 18.7 -9.5 3.1 27 84 A P T 5S- 0 0 96 0, 0.0 -1,-0.1 0, 0.0 -3,-0.1 0.625 121.9-100.0 -68.0 160.3 21.3 -9.8 1.8 28 85 A P T 5 - 0 0 87 0, 0.0 2,-0.6 0, 0.0 -3,-0.2 -0.235 30.7-155.1 -57.1 131.2 23.0 -8.3 4.8 29 86 A Q E < -C 24 0A 28 -5,-2.2 -5,-2.1 -4,-0.1 2,-0.3 -0.951 17.7-136.5-106.8 119.9 24.1 -4.7 4.7 30 87 A T E +C 23 0A 52 -2,-0.6 2,-0.3 -7,-0.2 -7,-0.2 -0.613 31.3 165.1 -82.6 133.7 27.0 -3.9 7.0 31 88 A L E -C 22 0A 3 -9,-2.5 -9,-2.9 -2,-0.3 2,-0.5 -0.986 35.9-124.3-144.1 147.4 26.8 -0.8 9.2 32 89 A N E -C 21 0A 3 -2,-0.3 88,-3.1 -11,-0.2 89,-0.7 -0.842 33.4-159.8 -92.3 132.6 28.7 0.5 12.2 33 90 A I E -Ce 20 121A 1 -13,-2.9 -13,-2.5 -2,-0.5 89,-0.3 -0.960 16.8-122.0-126.4 126.4 26.3 1.4 15.0 34 91 A L E -Ce 19 122A 17 87,-3.1 89,-3.4 -2,-0.5 2,-0.8 -0.361 25.0-130.8 -59.4 128.6 26.8 3.7 18.0 35 92 A V E + e 0 123A 1 -17,-3.1 2,-0.5 87,-0.2 -17,-0.3 -0.768 34.2 177.8 -85.0 113.6 26.2 1.8 21.3 36 93 A D E > + e 0 124A 18 87,-2.3 89,-2.6 -2,-0.8 3,-1.0 -0.864 24.5 174.3-125.8 100.2 23.8 4.1 23.2 37 94 A T T 3 S+ 0 0 0 -2,-0.5 166,-0.4 1,-0.2 194,-0.2 0.487 79.4 69.6 -80.1 1.1 22.5 3.1 26.6 38 95 A G T 3 S+ 0 0 14 164,-0.1 2,-0.3 88,-0.1 -1,-0.2 0.211 101.2 37.2-102.1 12.5 20.8 6.5 26.9 39 96 A S < - 0 0 26 -3,-1.0 87,-3.0 84,-0.2 92,-0.1 -0.918 64.1-140.3-150.9 176.4 18.1 6.0 24.2 40 97 A S + 0 0 2 90,-0.4 2,-0.4 -2,-0.3 100,-0.2 0.290 63.3 96.3-132.5 10.5 15.8 3.2 23.0 41 98 A N - 0 0 10 98,-0.1 83,-1.5 89,-0.1 2,-0.8 -0.849 58.9-143.5-105.5 141.0 15.6 3.4 19.2 42 99 A F E +F 123 0A 7 -2,-0.4 62,-2.6 81,-0.2 2,-0.4 -0.915 38.5 167.7 -97.2 112.6 17.6 1.5 16.6 43 100 A A E -Fg 122 104A 0 79,-2.0 79,-2.9 -2,-0.8 2,-0.3 -0.997 12.5-176.3-135.3 130.2 18.0 4.2 13.9 44 101 A V E -Fg 121 105A 0 60,-2.3 62,-3.0 -2,-0.4 77,-0.3 -0.952 36.9 -96.9-129.8 146.3 20.3 4.1 10.9 45 102 A G E + g 0 106A 1 75,-3.2 11,-2.8 -2,-0.3 62,-0.1 -0.377 40.5 174.0 -56.8 133.7 21.2 6.5 8.1 46 103 A A + 0 0 11 60,-2.3 12,-0.2 9,-0.2 -1,-0.1 0.185 57.1 45.7-130.0 13.8 19.0 5.6 5.1 47 104 A A S S- 0 0 33 59,-0.3 -1,-0.1 7,-0.1 9,-0.1 -0.983 98.6 -70.2-155.0 152.5 19.8 8.4 2.7 48 105 A P + 0 0 101 0, 0.0 -2,-0.1 0, 0.0 5,-0.1 -0.077 52.6 173.4 -44.6 138.0 22.9 10.2 1.3 49 106 A H > - 0 0 52 3,-0.4 3,-2.3 1,-0.1 5,-0.1 -0.975 42.2-119.9-152.1 139.3 24.7 12.4 3.9 50 107 A P T 3 S+ 0 0 120 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 0.785 115.7 44.9 -47.7 -33.3 28.0 14.4 3.7 51 108 A F T 3 S+ 0 0 93 64,-0.1 2,-0.4 -3,-0.0 65,-0.3 0.351 100.1 83.3 -97.1 3.8 29.3 12.4 6.7 52 109 A L < + 0 0 20 -3,-2.3 -3,-0.4 1,-0.1 3,-0.1 -0.923 43.4 179.9-112.7 131.0 28.2 8.9 5.6 53 110 A H S S+ 0 0 137 -2,-0.4 2,-0.3 1,-0.2 -1,-0.1 0.404 81.3 20.3-103.9 -0.6 30.0 6.7 3.1 54 111 A R + 0 0 75 -7,-0.1 2,-0.3 -5,-0.1 -1,-0.2 -0.976 66.6 175.8-159.4 156.9 27.3 4.0 3.4 55 112 A Y - 0 0 68 -2,-0.3 2,-0.3 -9,-0.1 -9,-0.2 -0.982 41.8 -75.8-160.2 162.7 23.7 3.7 4.5 56 113 A Y - 0 0 3 -11,-2.8 2,-0.8 -2,-0.3 -31,-0.1 -0.515 37.7-160.5 -67.7 122.4 20.7 1.4 4.8 57 114 A Q > - 0 0 63 -2,-0.3 3,-1.7 1,-0.2 4,-0.2 -0.840 7.6-174.6-111.0 93.4 19.2 0.8 1.4 58 115 A R G > S+ 0 0 42 -2,-0.8 3,-1.6 1,-0.3 6,-0.3 0.814 80.2 61.8 -54.9 -36.9 15.7 -0.5 2.0 59 116 A Q G 3 S+ 0 0 139 1,-0.3 -1,-0.3 3,-0.0 -2,-0.0 0.656 101.2 54.8 -69.2 -14.6 14.9 -1.2 -1.7 60 117 A L G < S+ 0 0 96 -3,-1.7 2,-0.6 -33,-0.0 -1,-0.3 0.404 90.8 88.3 -97.1 0.8 17.8 -3.7 -1.7 61 118 A S X - 0 0 11 -3,-1.6 3,-0.9 -4,-0.2 -36,-0.1 -0.895 56.1-165.3-105.4 119.8 16.4 -5.8 1.2 62 119 A S T 3 S+ 0 0 103 -36,-2.6 -1,-0.1 -2,-0.6 -4,-0.0 0.688 92.7 51.9 -73.5 -17.1 14.0 -8.6 0.4 63 120 A T T 3 S+ 0 0 29 -37,-0.3 -1,-0.2 25,-0.1 2,-0.1 0.353 79.6 125.9-101.8 3.4 13.0 -8.7 4.1 64 121 A Y < - 0 0 58 -3,-0.9 2,-0.4 -6,-0.3 23,-0.2 -0.399 40.0-167.2 -62.1 134.0 12.3 -5.1 4.5 65 122 A R E -H 86 0A 145 21,-2.1 21,-2.2 -2,-0.1 2,-0.5 -0.989 13.3-140.4-129.5 122.1 8.8 -4.3 5.9 66 123 A D E -H 85 0A 81 -2,-0.4 19,-0.3 19,-0.2 18,-0.0 -0.688 9.1-166.2 -84.4 124.3 7.4 -0.8 5.8 67 124 A L E - 0 0 75 17,-2.0 18,-0.2 -2,-0.5 -1,-0.1 0.502 31.6-134.4 -85.0 -5.3 5.5 0.3 8.9 68 125 A R E + 0 0 224 16,-0.5 2,-0.3 1,-0.2 17,-0.1 0.867 67.1 114.8 55.1 40.3 4.0 3.3 7.0 69 126 A K E -H 84 0A 109 15,-0.5 15,-3.1 2,-0.0 -2,-0.2 -0.999 55.9-142.3-143.0 137.0 4.8 5.6 10.0 70 127 A G E -H 83 0A 50 -2,-0.3 2,-0.3 13,-0.2 13,-0.2 -0.509 10.3-154.7 -94.1 166.8 7.2 8.5 10.5 71 128 A V E -H 82 0A 8 11,-2.3 11,-2.7 -2,-0.2 2,-0.5 -0.989 4.0-165.2-145.2 132.3 9.2 9.3 13.6 72 129 A Y E -H 81 0A 116 -2,-0.3 9,-0.2 9,-0.2 -2,-0.0 -0.979 7.7-178.3-120.1 120.1 10.6 12.7 14.8 73 130 A V E -H 80 0A 17 7,-2.8 7,-1.9 -2,-0.5 2,-0.3 -0.774 1.6-178.7-129.6 94.7 13.2 12.8 17.5 74 131 A P E +H 79 0A 57 0, 0.0 2,-0.3 0, 0.0 5,-0.3 -0.670 10.7 177.5 -87.2 137.8 14.5 16.1 18.8 75 132 A Y E > -H 78 0A 75 3,-3.0 3,-1.4 -2,-0.3 -2,-0.0 -0.890 44.9 -84.5-135.2 165.4 17.2 16.1 21.4 76 133 A T T 3 S+ 0 0 134 -2,-0.3 -1,-0.1 1,-0.3 3,-0.0 0.869 124.5 26.2 -33.5 -70.4 19.2 18.7 23.2 77 134 A Q T 3 S- 0 0 120 34,-0.1 2,-0.3 -3,-0.1 -1,-0.3 0.415 132.4 -36.6 -82.6 1.6 22.0 19.2 20.7 78 135 A G E < -H 75 0A 12 -3,-1.4 -3,-3.0 2,-0.0 2,-0.3 -0.895 58.3-104.9 178.2-147.4 20.0 18.2 17.5 79 136 A K E -HI 74 110A 76 31,-2.2 31,-2.9 -5,-0.3 2,-0.4 -0.969 7.6-153.7-171.2 154.5 17.4 15.9 15.9 80 137 A W E -HI 73 109A 9 -7,-1.9 -7,-2.8 -2,-0.3 2,-0.4 -0.997 11.2-167.7-137.2 142.2 16.8 12.9 13.7 81 138 A E E +HI 72 108A 52 27,-3.3 26,-2.0 -2,-0.4 27,-1.7 -0.972 19.7 147.1-128.6 144.3 13.8 12.1 11.6 82 139 A G E -HI 71 106A 6 -11,-2.7 -11,-2.3 -2,-0.4 2,-0.5 -0.937 43.5 -92.3-161.5-174.5 12.9 8.9 9.8 83 140 A E E -HI 70 105A 85 22,-2.2 22,-3.0 -2,-0.3 -13,-0.2 -0.949 39.1-130.2-115.1 126.5 10.6 6.3 8.5 84 141 A L E +HI 69 104A 3 -15,-3.1 -17,-2.0 -2,-0.5 -15,-0.5 -0.507 43.0 132.2 -80.3 142.8 9.7 3.2 10.6 85 142 A G E -HI 66 103A 2 18,-1.4 18,-2.8 -19,-0.3 2,-0.3 -0.914 42.1-118.2-166.0-175.3 10.0 -0.4 9.3 86 143 A T E +HI 65 102A 16 -21,-2.2 -21,-2.1 -2,-0.3 2,-0.3 -0.928 31.2 158.4-135.2 160.8 11.4 -3.8 10.4 87 144 A D E - I 0 101A 0 14,-1.6 14,-2.4 -2,-0.3 2,-0.4 -0.965 48.4 -71.9-167.3 175.2 14.0 -6.0 8.9 88 145 A L E - I 0 100A 51 -2,-0.3 -63,-1.9 12,-0.2 2,-0.4 -0.697 50.6-169.8 -84.0 131.2 16.4 -8.9 9.8 89 146 A V E +DI 24 99A 1 10,-3.0 10,-2.4 -2,-0.4 2,-0.3 -0.955 9.9 174.7-127.2 140.4 19.3 -7.7 12.0 90 147 A S E -DI 23 98A 25 -67,-2.0 -67,-2.5 -2,-0.4 8,-0.1 -0.918 26.6-139.6-138.3 161.3 22.5 -9.5 13.1 91 148 A I > - 0 0 8 6,-0.5 3,-1.2 4,-0.5 6,-0.2 -0.943 14.6-156.1-124.9 105.1 25.6 -8.6 15.1 92 149 A P T 3 S+ 0 0 45 0, 0.0 2,-0.6 0, 0.0 -1,-0.1 0.872 95.4 38.2 -46.5 -48.4 28.6 -10.3 13.3 93 150 A H T 3 S+ 0 0 97 -72,-0.4 -84,-0.1 -84,-0.1 3,-0.1 -0.458 115.3 66.6-104.7 57.5 30.7 -10.3 16.5 94 151 A G S < S- 0 0 0 -3,-1.2 2,-0.1 -2,-0.6 -87,-0.1 -0.554 99.7 -24.1-146.4-150.2 27.8 -11.0 18.8 95 152 A P - 0 0 18 0, 0.0 2,-2.4 0, 0.0 -4,-0.5 -0.445 66.4-113.6 -70.6 144.1 25.4 -13.9 19.5 96 153 A N S S+ 0 0 127 -2,-0.1 2,-0.3 -6,-0.1 -6,-0.0 -0.362 80.8 105.1 -81.1 66.0 25.0 -16.2 16.6 97 154 A V - 0 0 46 -2,-2.4 -6,-0.5 -6,-0.2 2,-0.4 -0.939 56.7-147.0-140.3 158.7 21.4 -15.2 16.0 98 155 A T E - I 0 90A 82 -2,-0.3 2,-0.3 -8,-0.1 -8,-0.2 -0.996 22.5-175.8-127.5 132.8 19.3 -13.1 13.6 99 156 A V E - I 0 89A 3 -10,-2.4 -10,-3.0 -2,-0.4 2,-0.7 -0.924 29.9-116.4-131.3 155.0 16.2 -11.3 14.7 100 157 A R E + I 0 88A 55 -2,-0.3 2,-0.3 -12,-0.2 -12,-0.2 -0.822 47.6 171.8 -90.3 122.7 13.5 -9.2 13.2 101 158 A A E - I 0 87A 2 -14,-2.4 -14,-1.6 -2,-0.7 2,-0.2 -0.897 38.3 -99.2-132.6 156.2 13.7 -5.7 14.7 102 159 A N E - I 0 86A 29 36,-0.5 2,-0.4 -2,-0.3 -16,-0.3 -0.490 39.5-171.5 -68.3 141.4 12.2 -2.3 14.3 103 160 A I E - I 0 85A 3 -18,-2.8 -18,-1.4 -2,-0.2 2,-0.7 -0.987 17.7-148.3-139.0 127.2 14.5 0.1 12.4 104 161 A A E -gI 43 84A 1 -62,-2.6 -60,-2.3 -2,-0.4 2,-0.9 -0.874 17.2-146.1 -94.6 116.7 14.0 3.8 11.9 105 162 A A E -gI 44 83A 1 -22,-3.0 -22,-2.2 -2,-0.7 2,-0.4 -0.751 17.9-136.0 -85.3 109.1 15.4 4.7 8.5 106 163 A I E +gI 45 82A 5 -62,-3.0 -60,-2.3 -2,-0.9 -59,-0.3 -0.527 36.3 162.9 -72.9 119.6 16.9 8.2 9.0 107 164 A T E + 0 0 48 -26,-2.0 2,-0.3 -2,-0.4 -25,-0.2 0.596 67.9 24.3-109.5 -16.9 16.0 10.5 6.2 108 165 A E E + I 0 81A 121 -27,-1.7 -27,-3.3 2,-0.0 -1,-0.3 -0.986 66.6 165.8-151.3 137.2 16.7 13.9 7.8 109 166 A S E - 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