==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=3-JUN-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE ACTIVATOR 29-JAN-12 2LOZ . COMPND 2 MOLECULE: TENSIN-LIKE C1 DOMAIN-CONTAINING PHOSPHATASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.LIU,L.CHEN,G.ZHU . 161 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8418.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 97 60.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 44 27.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 10 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 13 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 25 15.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 1 1 1 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1263 A M > 0 0 106 0, 0.0 3,-0.8 0, 0.0 145,-0.1 0.000 360.0 360.0 360.0 0.8 2.8 -10.3 13.3 2 1264 A S T 3 + 0 0 64 1,-0.2 3,-0.5 2,-0.1 144,-0.0 0.818 360.0 51.2 -78.0 -30.1 4.9 -9.5 16.4 3 1265 A T T > S+ 0 0 126 1,-0.2 3,-1.1 2,-0.1 -1,-0.2 0.104 76.7 110.9 -92.0 21.7 8.0 -10.8 14.7 4 1266 A A T X> + 0 0 6 -3,-0.8 3,-2.1 1,-0.3 4,-1.0 0.477 42.4 101.3 -74.8 -2.6 7.3 -8.7 11.7 5 1267 A A H 3> + 0 0 31 -3,-0.5 4,-3.7 1,-0.3 5,-0.4 0.783 64.2 76.9 -52.3 -27.8 10.3 -6.6 12.6 6 1268 A D H <4 S+ 0 0 71 -3,-1.1 4,-0.4 1,-0.2 -1,-0.3 0.820 97.8 43.0 -53.8 -34.9 12.1 -8.5 9.8 7 1269 A L H <>>S+ 0 0 3 -3,-2.1 4,-3.0 2,-0.2 5,-0.8 0.879 120.1 39.5 -81.2 -38.8 10.3 -6.4 7.2 8 1270 A L H <5S+ 0 0 0 -4,-1.0 152,-1.2 2,-0.2 50,-0.5 0.813 111.2 56.4 -81.8 -32.6 10.7 -3.0 8.9 9 1271 A R T <5S+ 0 0 155 -4,-3.7 -1,-0.2 150,-0.3 -3,-0.2 0.711 120.2 34.3 -70.1 -20.4 14.3 -3.6 10.2 10 1272 A Q T 45S- 0 0 95 -5,-0.4 146,-0.5 -4,-0.4 -2,-0.2 0.870 94.6-142.2 -97.1 -55.9 15.1 -4.2 6.6 11 1273 A G T <5 - 0 0 0 -4,-3.0 144,-1.2 142,-0.2 143,-0.3 0.922 19.4-144.5 85.3 66.0 12.9 -1.9 4.6 12 1274 A A < - 0 0 0 -5,-0.8 44,-2.6 141,-0.3 2,-0.8 -0.433 8.7-155.1 -69.3 129.4 12.0 -3.9 1.6 13 1275 A A E +A 55 0A 22 42,-0.2 42,-0.3 -2,-0.2 141,-0.1 -0.845 32.6 163.9-105.2 91.8 11.6 -2.1 -1.7 14 1276 A C E -A 54 0A 3 40,-2.2 40,-3.2 -2,-0.8 2,-0.4 -0.217 37.5-101.7 -98.9-172.0 9.2 -4.4 -3.6 15 1277 A S E -A 53 0A 27 38,-0.3 2,-0.3 -2,-0.1 38,-0.3 -0.960 36.6-179.5-118.0 133.2 7.1 -4.0 -6.7 16 1278 A V E -A 52 0A 7 36,-2.9 36,-3.0 -2,-0.4 2,-0.7 -0.808 33.8-102.3-127.0 169.0 3.3 -3.4 -6.6 17 1279 A L E -AB 51 123A 8 106,-2.3 106,-2.6 -2,-0.3 2,-0.3 -0.829 35.4-143.3 -95.6 113.3 0.5 -3.0 -9.1 18 1280 A Y E +AB 50 122A 10 32,-3.7 32,-1.2 -2,-0.7 104,-0.2 -0.575 33.2 154.9 -79.0 135.1 -0.5 0.6 -9.4 19 1281 A L E - 0 0 4 102,-1.4 2,-0.3 -2,-0.3 103,-0.2 0.619 50.7 -60.6-120.9 -73.1 -4.2 1.3 -9.9 20 1282 A T E - B 0 121A 2 101,-1.6 101,-2.6 25,-0.0 2,-0.4 -0.981 37.4-107.3-172.3 168.6 -5.4 4.8 -8.8 21 1283 A S E - B 0 120A 38 -2,-0.3 2,-0.4 99,-0.3 99,-0.3 -0.919 29.4-175.5-113.9 138.7 -5.8 7.2 -5.8 22 1284 A V E - B 0 119A 21 97,-2.8 97,-3.0 -2,-0.4 2,-0.2 -0.992 29.1-111.4-135.2 142.2 -9.1 8.0 -4.1 23 1285 A E E + B 0 118A 108 -2,-0.4 95,-0.2 95,-0.2 84,-0.0 -0.515 37.8 162.5 -72.7 132.6 -10.0 10.5 -1.4 24 1286 A T > + 0 0 1 93,-1.6 3,-1.1 -2,-0.2 94,-0.2 0.019 28.1 128.6-138.8 25.8 -11.0 8.9 1.9 25 1287 A E T 3 S+ 0 0 68 92,-0.4 93,-0.1 1,-0.3 7,-0.0 0.799 83.0 39.2 -53.9 -34.9 -10.6 11.8 4.3 26 1288 A S T 3 S+ 0 0 109 91,-0.1 -1,-0.3 2,-0.0 2,-0.1 0.535 106.5 87.0 -94.7 -7.7 -14.1 11.3 5.7 27 1289 A L S < S- 0 0 39 -3,-1.1 2,-0.1 90,-0.2 -3,-0.1 -0.351 72.2-123.8 -90.3 169.8 -13.8 7.5 5.6 28 1290 A T > - 0 0 83 -2,-0.1 4,-1.4 1,-0.0 5,-0.1 -0.238 44.2 -75.8 -97.2-169.7 -12.5 5.1 8.2 29 1291 A G H >> S+ 0 0 6 2,-0.2 4,-1.1 1,-0.2 3,-0.8 0.978 124.9 21.6 -54.8 -79.9 -9.7 2.5 7.8 30 1292 A P H 3> S+ 0 0 58 0, 0.0 4,-1.7 0, 0.0 -1,-0.2 0.870 121.7 59.3 -60.2 -38.9 -11.3 -0.4 5.8 31 1293 A Q H 3> S+ 0 0 107 1,-0.2 4,-2.6 2,-0.2 5,-0.3 0.803 98.5 61.1 -61.3 -29.4 -14.1 1.8 4.4 32 1294 A A H X S+ 0 0 56 -4,-3.3 4,-3.3 1,-0.2 3,-0.8 0.901 112.2 49.5 -56.2 -44.9 -15.3 0.4 -5.6 39 1301 A A H 3X>S+ 0 0 29 -4,-2.4 4,-2.3 -5,-0.3 5,-1.4 0.861 106.0 57.4 -63.5 -35.4 -14.9 3.7 -7.3 40 1302 A A H 3<5S+ 0 0 6 -4,-1.2 -1,-0.3 -5,-0.3 6,-0.2 0.759 116.2 36.5 -66.2 -24.7 -11.9 2.3 -9.3 41 1303 A L H <<5S+ 0 0 63 -4,-1.1 -2,-0.2 -3,-0.8 -1,-0.2 0.879 122.2 40.6 -92.8 -48.1 -14.3 -0.4 -10.6 42 1304 A S H <5S+ 0 0 102 -4,-3.3 -3,-0.2 -5,-0.2 -2,-0.2 0.899 133.8 22.1 -69.9 -43.3 -17.6 1.6 -11.0 43 1305 A C T <5S- 0 0 103 -4,-2.3 -3,-0.2 -5,-0.3 -1,-0.1 0.840 87.4-156.0 -93.3 -39.3 -16.0 4.8 -12.4 44 1306 A S < + 0 0 66 -5,-1.4 -4,-0.2 -6,-0.2 -3,-0.1 0.996 17.9 176.4 58.4 70.9 -12.7 3.3 -13.7 45 1307 A P + 0 0 67 0, 0.0 -5,-0.1 0, 0.0 -1,-0.1 0.803 69.8 48.8 -72.8 -29.9 -10.5 6.4 -13.6 46 1308 A R - 0 0 87 -6,-0.2 -26,-0.0 1,-0.2 -3,-0.0 -0.951 64.8-171.6-116.0 129.1 -7.5 4.3 -14.7 47 1309 A P S S+ 0 0 104 0, 0.0 -1,-0.2 0, 0.0 -3,-0.0 0.970 72.0 26.7 -80.7 -75.7 -7.7 1.9 -17.7 48 1310 A T S S- 0 0 95 47,-0.1 2,-0.1 48,-0.0 47,-0.1 -0.823 77.6-144.8 -97.5 124.4 -4.5 -0.1 -17.9 49 1311 A P - 0 0 18 0, 0.0 2,-0.3 0, 0.0 -30,-0.2 -0.291 12.7-153.5 -79.5 168.6 -2.5 -0.7 -14.6 50 1312 A A E -A 18 0A 12 -32,-1.2 -32,-3.7 -2,-0.1 2,-0.6 -0.989 19.8-110.5-145.8 153.4 1.2 -0.9 -14.2 51 1313 A V E +A 17 0A 60 -2,-0.3 -34,-0.2 -34,-0.2 2,-0.2 -0.744 45.2 167.3 -87.2 120.9 3.9 -2.4 -11.9 52 1314 A V E -A 16 0A 0 -36,-3.0 -36,-2.9 -2,-0.6 2,-0.3 -0.677 36.5 -86.5-123.8 178.1 5.7 0.2 -9.9 53 1315 A H E -AC 15 64A 65 11,-2.0 11,-2.8 -38,-0.3 2,-0.4 -0.635 35.9-174.5 -92.5 148.8 8.0 0.2 -6.9 54 1316 A F E -AC 14 63A 0 -40,-3.2 -40,-2.2 -2,-0.3 2,-0.5 -0.993 8.1-157.6-143.2 131.3 6.9 0.2 -3.2 55 1317 A K E -AC 13 62A 49 7,-3.8 7,-2.6 -2,-0.4 2,-0.6 -0.946 4.2-155.2-117.3 127.2 9.0 0.5 -0.1 56 1318 A V E + C 0 61A 1 -44,-2.6 2,-0.3 -2,-0.5 -44,-0.3 -0.878 26.1 157.1-102.2 120.4 7.8 -0.6 3.3 57 1319 A S E > - C 0 60A 4 3,-0.6 3,-1.3 -2,-0.6 -49,-0.1 -0.993 48.7-129.7-142.4 149.7 9.4 1.1 6.3 58 1320 A A T 3 S+ 0 0 1 -50,-0.5 3,-0.1 -2,-0.3 103,-0.1 0.636 111.4 58.7 -71.9 -13.8 8.5 1.6 10.0 59 1321 A Q T 3 S- 0 0 101 1,-0.4 19,-3.0 -51,-0.1 20,-0.4 0.515 128.9 -55.1 -90.6 -7.0 9.3 5.3 9.5 60 1322 A G E < -CD 57 77A 5 -3,-1.3 -3,-0.6 17,-0.4 -1,-0.4 -0.755 58.2 -82.5 148.4 166.2 6.7 5.5 6.8 61 1323 A I E -CD 56 76A 2 15,-2.5 15,-0.8 -2,-0.2 2,-0.4 -0.740 37.9-162.6-100.4 145.4 5.6 4.0 3.5 62 1324 A T E -C 55 0A 31 -7,-2.6 -7,-3.8 -2,-0.3 2,-0.3 -0.991 8.9-155.7-134.6 132.6 7.1 5.1 0.2 63 1325 A L E -C 54 0A 12 -2,-0.4 2,-0.4 -9,-0.2 -9,-0.3 -0.684 18.0-153.2 -95.3 153.9 5.9 4.7 -3.4 64 1326 A T E -C 53 0A 27 -11,-2.8 -11,-2.0 -2,-0.3 2,-1.4 -0.989 17.4-135.8-139.6 134.1 8.5 4.7 -6.2 65 1327 A D + 0 0 31 -2,-0.4 -13,-0.1 8,-0.4 7,-0.1 -0.659 31.7 167.0 -83.9 87.7 8.4 5.7 -9.9 66 1328 A N S S+ 0 0 46 -2,-1.4 -1,-0.2 1,-0.1 -14,-0.1 0.895 85.6 8.0 -69.7 -42.0 10.3 2.8 -11.4 67 1329 A Q S S- 0 0 126 -3,-0.2 -1,-0.1 -16,-0.1 -2,-0.1 0.600 86.9-142.7-113.4 -20.2 9.3 3.6 -15.0 68 1330 A R + 0 0 179 -4,-0.1 -3,-0.1 1,-0.1 -16,-0.0 0.892 56.4 133.2 56.6 42.9 7.5 7.0 -14.4 69 1331 A K S S+ 0 0 136 2,-0.0 -1,-0.1 0, 0.0 -4,-0.0 0.909 76.5 12.5 -89.3 -48.1 4.9 6.1 -17.0 70 1332 A L S S- 0 0 77 1,-0.0 2,-0.1 0, 0.0 -5,-0.0 0.930 124.1 -61.0 -92.9 -64.8 1.7 7.0 -15.3 71 1333 A F + 0 0 133 2,-0.0 2,-0.3 0, 0.0 -2,-0.0 -0.424 68.8 142.4 170.0 102.2 2.5 9.1 -12.2 72 1334 A F + 0 0 13 -2,-0.1 -7,-0.1 1,-0.1 3,-0.1 -0.955 5.8 136.6-145.2 162.9 4.6 7.9 -9.2 73 1335 A R - 0 0 144 1,-0.3 -8,-0.4 -2,-0.3 2,-0.3 0.097 66.9 -37.1-168.9 -62.0 7.2 9.5 -6.9 74 1336 A R - 0 0 169 -10,-0.2 -1,-0.3 -12,-0.1 -12,-0.1 -0.893 44.6-137.0-163.4-171.4 6.8 8.7 -3.2 75 1337 A H - 0 0 21 -14,-0.3 -13,-0.2 -2,-0.3 -1,-0.0 -0.043 41.5 -59.6-130.9-124.8 4.3 8.1 -0.5 76 1338 A Y E -D 61 0A 28 -15,-0.8 -15,-2.5 -2,-0.1 34,-0.1 -0.996 35.3-129.5-141.2 139.3 3.9 9.2 3.2 77 1339 A P E >> -D 60 0A 59 0, 0.0 3,-2.5 0, 0.0 4,-2.1 -0.164 45.4 -88.4 -75.0 176.1 6.0 8.8 6.4 78 1340 A V T 34 S+ 0 0 34 -19,-3.0 -18,-0.2 1,-0.3 -19,-0.1 0.776 126.3 65.9 -57.7 -25.9 4.6 7.5 9.7 79 1341 A N T 34 S+ 0 0 128 -20,-0.4 -1,-0.3 1,-0.2 -19,-0.1 0.585 113.5 30.7 -73.7 -9.8 3.8 11.2 10.5 80 1342 A S T <4 S+ 0 0 23 -3,-2.5 29,-3.0 28,-0.0 -2,-0.2 0.627 96.8 97.1-118.8 -27.1 1.2 11.2 7.7 81 1343 A I E < +E 108 0A 8 -4,-2.1 27,-0.3 27,-0.3 3,-0.1 -0.462 35.4 166.9 -70.1 134.4 0.0 7.5 7.6 82 1344 A T E - 0 0 50 25,-3.3 2,-0.3 1,-0.4 26,-0.2 0.599 63.0 -5.0-118.6 -24.9 -3.2 6.9 9.5 83 1345 A F E -E 107 0A 56 24,-2.0 24,-3.6 -54,-0.1 -1,-0.4 -0.984 50.2-159.5-167.8 157.1 -4.2 3.4 8.3 84 1346 A S E +E 106 0A 2 -2,-0.3 2,-0.3 22,-0.3 22,-0.2 -0.993 15.3 170.4-145.8 136.8 -3.3 0.5 5.9 85 1347 A S E -E 105 0A 17 20,-2.5 20,-2.5 -2,-0.3 -2,-0.0 -0.982 34.6-142.5-146.0 158.1 -5.4 -2.4 4.6 86 1348 A T S S- 0 0 11 1,-0.4 17,-0.3 -2,-0.3 38,-0.1 0.620 87.0 -17.4 -92.9 -18.7 -5.2 -5.1 2.0 87 1349 A D - 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