==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-JUL-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 04-FEB-10 3LP6 . COMPND 2 MOLECULE: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTI . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR H.KIM,M.YU,L.-W.HUNG,T.C.TERWILLIGER,C.-Y.KIM,INTEGRATED CEN . 669 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 27094.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 514 76.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 88 13.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 43 6.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 74 11.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 283 42.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 1 6 0 1 2 0 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 RESIDUES PER ALPHA HELIX . 0 4 0 0 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 6 A E 0 0 192 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 145.4 66.8 7.7 12.0 2 7 A R - 0 0 162 1,-0.1 31,-0.1 29,-0.1 55,-0.0 -0.437 360.0 -94.3 -71.3 141.9 64.0 7.5 14.5 3 8 A P - 0 0 31 0, 0.0 29,-0.3 0, 0.0 -1,-0.1 -0.206 32.0-173.6 -58.8 142.0 62.4 10.9 15.5 4 9 A R S S+ 0 0 51 27,-2.9 55,-3.4 1,-0.2 56,-1.2 0.528 75.3 40.6-107.2 -18.8 63.7 12.6 18.7 5 10 A V E -ab 32 60A 0 26,-1.2 28,-1.8 53,-0.2 2,-0.4 -0.998 69.7-152.3-132.6 135.0 61.2 15.4 18.7 6 11 A G E -ab 33 61A 0 54,-2.0 56,-3.4 -2,-0.4 2,-0.5 -0.883 3.5-162.1-105.2 139.5 57.5 15.2 17.9 7 12 A V E +ab 34 62A 0 26,-2.5 28,-2.2 -2,-0.4 2,-0.3 -0.964 22.7 171.0-121.3 110.8 55.6 18.2 16.5 8 13 A I E +ab 35 63A 0 54,-3.0 56,-2.5 -2,-0.5 2,-0.3 -0.840 12.3 174.6-126.7 159.5 51.9 17.9 16.9 9 14 A M E -ab 36 64A 6 26,-1.5 28,-2.5 -2,-0.3 56,-0.2 -0.980 38.8-116.2-159.4 156.7 48.8 20.0 16.5 10 15 A G S S+ 0 0 11 54,-1.1 2,-0.3 -2,-0.3 28,-0.1 0.698 95.0 18.7 -76.0 -20.1 45.0 19.7 16.7 11 16 A S > - 0 0 28 26,-0.1 3,-2.1 1,-0.1 4,-0.2 -0.997 68.1-123.4-149.6 149.7 44.4 20.5 13.0 12 17 A D G > S+ 0 0 123 -2,-0.3 3,-1.5 1,-0.3 -1,-0.1 0.714 110.8 72.6 -63.9 -16.5 46.2 20.6 9.7 13 18 A S G 3 S+ 0 0 83 1,-0.3 -1,-0.3 2,-0.1 4,-0.2 0.608 86.5 63.4 -72.5 -11.6 45.0 24.2 9.7 14 19 A D G X> S+ 0 0 13 -3,-2.1 4,-2.8 1,-0.2 3,-1.0 0.533 79.1 90.8 -82.7 -9.1 47.6 24.9 12.4 15 20 A W H <> S+ 0 0 110 -3,-1.5 4,-2.7 1,-0.3 5,-0.2 0.852 71.9 64.1 -62.1 -39.8 50.4 24.0 9.9 16 21 A P H 34 S+ 0 0 102 0, 0.0 -1,-0.3 0, 0.0 4,-0.2 0.857 117.8 31.8 -51.2 -34.5 51.0 27.5 8.5 17 22 A V H X4 S+ 0 0 36 -3,-1.0 3,-1.4 -4,-0.2 4,-0.3 0.909 120.7 47.4 -83.6 -52.0 52.1 28.3 12.1 18 23 A M H >X S+ 0 0 0 -4,-2.8 3,-1.6 1,-0.3 4,-1.2 0.687 90.3 81.7 -72.2 -18.0 53.6 25.0 13.3 19 24 A A H 3X S+ 0 0 23 -4,-2.7 4,-2.3 1,-0.3 -1,-0.3 0.826 82.7 65.6 -54.8 -32.4 55.7 24.5 10.1 20 25 A D H <> S+ 0 0 86 -3,-1.4 4,-2.2 1,-0.2 -1,-0.3 0.813 96.4 54.9 -62.4 -29.7 58.2 26.8 11.6 21 26 A A H <> S+ 0 0 0 -3,-1.6 4,-2.3 -4,-0.3 -1,-0.2 0.922 108.7 47.5 -69.3 -41.1 59.0 24.3 14.4 22 27 A A H X S+ 0 0 26 -4,-1.2 4,-2.3 1,-0.2 -2,-0.2 0.912 111.4 51.8 -64.6 -40.4 59.7 21.6 11.8 23 28 A A H X S+ 0 0 55 -4,-2.3 4,-2.0 2,-0.2 -1,-0.2 0.912 108.8 50.1 -61.9 -44.0 61.9 24.1 10.0 24 29 A A H X S+ 0 0 9 -4,-2.2 4,-1.0 1,-0.2 -2,-0.2 0.921 111.1 48.9 -62.3 -44.5 63.9 24.9 13.1 25 30 A L H ><>S+ 0 0 0 -4,-2.3 5,-2.4 1,-0.2 3,-0.6 0.900 109.8 52.0 -60.5 -41.4 64.5 21.3 13.9 26 31 A A H ><5S+ 0 0 61 -4,-2.3 3,-1.9 1,-0.2 -1,-0.2 0.871 100.8 61.6 -66.4 -35.1 65.6 20.6 10.4 27 32 A E H 3<5S+ 0 0 123 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.832 110.7 41.0 -58.3 -31.7 68.1 23.4 10.5 28 33 A F T <<5S- 0 0 6 -4,-1.0 -1,-0.3 -3,-0.6 -2,-0.2 0.215 114.2-118.2-100.6 13.5 69.8 21.5 13.4 29 34 A D T < 5 + 0 0 112 -3,-1.9 -3,-0.2 1,-0.2 -2,-0.1 0.837 57.4 157.7 53.3 37.7 69.4 18.1 11.7 30 35 A I < - 0 0 15 -5,-2.4 -1,-0.2 -6,-0.1 -2,-0.1 -0.850 45.5-121.5 -92.8 121.3 67.2 16.8 14.5 31 36 A P + 0 0 28 0, 0.0 -27,-2.9 0, 0.0 -26,-1.2 -0.393 46.4 167.9 -58.9 132.0 65.0 13.8 13.4 32 37 A A E -a 5 0A 44 -29,-0.3 2,-0.3 -28,-0.2 -26,-0.2 -0.943 27.9-148.1-146.3 162.1 61.4 14.8 13.9 33 38 A E E -a 6 0A 28 -28,-1.8 -26,-2.5 -2,-0.3 2,-0.4 -0.932 10.3-147.6-130.6 157.1 57.9 13.7 13.1 34 39 A V E +a 7 0A 73 -2,-0.3 2,-0.3 -28,-0.2 -26,-0.2 -0.972 21.1 172.6-125.8 141.5 54.8 15.8 12.6 35 40 A R E -a 8 0A 104 -28,-2.2 -26,-1.5 -2,-0.4 2,-0.7 -0.999 34.9-131.4-147.5 145.4 51.2 14.7 13.5 36 41 A V E +a 9 0A 87 -2,-0.3 2,-0.4 -28,-0.2 -26,-0.2 -0.915 40.8 162.4 -92.5 119.5 47.7 15.9 13.7 37 42 A V - 0 0 7 -28,-2.5 2,-0.5 -2,-0.7 -26,-0.1 -0.975 21.6-156.9-141.5 118.6 46.5 14.8 17.2 38 43 A S > - 0 0 7 -2,-0.4 4,-1.8 1,-0.1 8,-0.4 -0.888 13.5-160.0-109.0 127.8 43.5 16.5 18.7 39 44 A A T 4 S+ 0 0 5 -2,-0.5 -1,-0.1 1,-0.2 8,-0.1 0.860 98.2 36.9 -67.3 -35.8 42.8 16.5 22.5 40 45 A H T 4 S+ 0 0 23 2,-0.1 -1,-0.2 1,-0.1 -2,-0.0 0.777 128.1 31.0 -90.3 -28.4 39.1 17.2 21.9 41 46 A R T 4 S+ 0 0 140 1,-0.1 -2,-0.2 -31,-0.1 -1,-0.1 0.619 133.4 26.0-108.7 -18.9 38.4 15.1 18.8 42 47 A T X + 0 0 57 -4,-1.8 4,-2.6 1,-0.1 5,-0.2 -0.381 67.3 152.9-137.3 60.7 40.9 12.2 19.2 43 48 A P H > S+ 0 0 10 0, 0.0 4,-2.6 0, 0.0 5,-0.2 0.864 76.3 51.6 -59.6 -38.2 41.5 12.0 23.0 44 49 A E H > S+ 0 0 118 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.934 112.1 45.9 -63.9 -45.2 42.4 8.3 22.9 45 50 A A H > S+ 0 0 51 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.890 113.2 51.2 -61.0 -40.7 44.9 8.9 20.1 46 51 A M H X S+ 0 0 0 -4,-2.6 4,-2.3 -8,-0.4 5,-0.2 0.936 110.3 48.0 -62.4 -47.7 46.3 11.8 22.1 47 52 A F H X S+ 0 0 28 -4,-2.6 4,-2.7 1,-0.2 5,-0.2 0.928 113.8 47.2 -61.4 -45.1 46.7 9.7 25.2 48 53 A S H X S+ 0 0 61 -4,-2.6 4,-2.6 2,-0.2 -1,-0.2 0.899 110.2 53.0 -61.4 -42.3 48.4 6.9 23.3 49 54 A Y H X S+ 0 0 12 -4,-2.6 4,-0.9 2,-0.2 -2,-0.2 0.940 114.1 41.9 -59.7 -47.6 50.7 9.3 21.5 50 55 A A H >< S+ 0 0 0 -4,-2.3 3,-0.6 1,-0.2 4,-0.5 0.925 115.9 48.1 -66.0 -48.1 51.9 10.9 24.8 51 56 A R H 3< S+ 0 0 108 -4,-2.7 4,-0.4 1,-0.2 3,-0.2 0.881 116.8 43.2 -61.6 -39.1 52.1 7.6 26.7 52 57 A G H 3X S+ 0 0 26 -4,-2.6 4,-1.7 -5,-0.2 -1,-0.2 0.599 89.5 92.8 -82.6 -10.8 54.1 5.9 23.9 53 58 A A H S+ 0 0 0 -4,-0.9 5,-2.2 -3,-0.6 4,-0.6 0.898 85.2 43.6 -56.0 -54.8 56.4 8.8 23.2 54 59 A A H >45S+ 0 0 20 -4,-0.5 3,-1.4 1,-0.2 -1,-0.2 0.909 112.9 53.1 -61.4 -42.0 59.4 8.0 25.4 55 60 A A H 345S+ 0 0 89 -4,-0.4 -1,-0.2 1,-0.3 -2,-0.2 0.840 105.8 54.3 -61.3 -33.2 59.4 4.3 24.4 56 61 A R H 3<5S- 0 0 87 -4,-1.7 -1,-0.3 -3,-0.4 -2,-0.2 0.592 127.0-101.8 -76.3 -10.6 59.5 5.3 20.7 57 62 A G T <<5S+ 0 0 9 -3,-1.4 -3,-0.2 -4,-0.6 -2,-0.1 0.423 70.5 148.8 103.6 0.4 62.6 7.4 21.4 58 63 A L < - 0 0 4 -5,-2.2 -1,-0.3 -6,-0.2 -53,-0.2 -0.420 22.9-178.0 -65.7 144.4 61.1 10.9 21.6 59 64 A E + 0 0 33 -55,-3.4 2,-0.3 1,-0.4 -54,-0.2 0.578 68.5 18.6-114.8 -20.1 62.8 13.3 23.9 60 65 A V E -b 5 0A 0 -56,-1.2 -54,-2.0 21,-0.1 2,-0.5 -0.988 62.2-151.9-149.9 143.8 60.6 16.4 23.6 61 66 A I E -bc 6 83A 0 21,-1.7 23,-2.9 -2,-0.3 2,-0.5 -0.990 4.8-161.3-119.9 127.7 57.1 17.0 22.3 62 67 A I E -bc 7 84A 0 -56,-3.4 -54,-3.0 -2,-0.5 2,-0.4 -0.936 16.7-175.3-101.7 126.3 56.1 20.4 20.7 63 68 A A E -bc 8 85A 0 21,-3.1 23,-2.7 -2,-0.5 2,-0.4 -0.990 9.6-162.7-129.5 130.0 52.3 20.8 20.7 64 69 A G E +bc 9 86A 0 -56,-2.5 -54,-1.1 -2,-0.4 2,-0.3 -0.899 19.1 154.3-111.9 139.2 50.3 23.6 19.2 65 70 A A E - c 0 87A 11 21,-1.7 23,-2.5 -2,-0.4 2,-0.3 -0.983 23.0-144.3-157.2 155.3 46.7 24.4 20.0 66 71 A G E + c 0 88A 10 -2,-0.3 2,-0.2 21,-0.2 4,-0.2 -0.795 59.9 1.8-122.9 163.4 44.3 27.4 19.9 67 72 A G S S+ 0 0 1 21,-0.6 2,-2.2 -2,-0.3 34,-0.3 -0.486 136.8 12.3 71.2-130.7 41.4 28.8 21.9 68 73 A A S S- 0 0 1 545,-2.3 2,-0.9 -2,-0.2 -2,-0.2 -0.616 95.2-167.2 -71.9 80.9 40.7 26.6 24.9 69 74 A A + 0 0 1 -2,-2.2 4,-0.2 28,-0.3 -2,-0.1 -0.670 27.9 152.5 -88.1 103.2 44.0 25.0 24.0 70 75 A H > + 0 0 1 -2,-0.9 4,-2.6 -4,-0.2 5,-0.3 0.587 45.2 90.3-107.5 -14.6 44.3 21.8 26.0 71 76 A L H > S+ 0 0 3 1,-0.2 4,-2.4 2,-0.2 5,-0.3 0.915 88.1 46.6 -56.3 -51.5 46.6 19.6 23.9 72 77 A P H > S+ 0 0 0 0, 0.0 4,-2.5 0, 0.0 -1,-0.2 0.931 116.1 45.5 -57.6 -44.5 49.9 20.7 25.4 73 78 A G H > S+ 0 0 1 -4,-0.2 4,-1.8 1,-0.2 -2,-0.2 0.901 113.5 47.9 -66.8 -41.2 48.7 20.3 29.0 74 79 A M H X S+ 0 0 2 -4,-2.6 4,-0.7 2,-0.2 -1,-0.2 0.854 112.0 49.8 -71.6 -33.2 47.0 16.9 28.4 75 80 A V H >X S+ 0 0 0 -4,-2.4 3,-1.3 -5,-0.3 4,-0.7 0.949 110.6 50.4 -65.9 -44.9 50.0 15.6 26.6 76 81 A A H >< S+ 0 0 0 -4,-2.5 3,-0.6 1,-0.3 -2,-0.2 0.840 104.6 59.1 -62.5 -30.9 52.2 16.7 29.5 77 82 A A H 3< S+ 0 0 9 -4,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.772 110.6 42.4 -64.8 -25.6 49.8 15.0 31.9 78 83 A A H << S+ 0 0 2 -3,-1.3 -1,-0.2 -4,-0.7 -2,-0.2 0.425 111.6 50.2-108.4 -1.9 50.5 11.7 30.2 79 84 A T << - 0 0 1 -4,-0.7 -28,-0.1 -3,-0.6 4,-0.1 -0.950 62.9-140.8-134.1 153.5 54.3 11.7 29.6 80 85 A P S S+ 0 0 16 0, 0.0 386,-0.1 0, 0.0 387,-0.1 0.553 76.3 104.5 -84.4 -8.1 57.4 12.3 31.8 81 86 A L S S- 0 0 0 -31,-0.2 2,-0.2 1,-0.1 -2,-0.2 -0.349 85.2 -98.0 -71.7 152.7 58.9 14.1 28.8 82 87 A P - 0 0 0 0, 0.0 -21,-1.7 0, 0.0 2,-0.4 -0.500 40.1-155.4 -66.3 136.5 59.2 17.9 28.6 83 88 A V E -c 61 0A 0 27,-0.3 29,-2.7 -2,-0.2 2,-0.5 -0.968 5.6-155.7-120.7 131.2 56.4 19.4 26.5 84 89 A I E -cd 62 112A 0 -23,-2.9 -21,-3.1 -2,-0.4 2,-0.5 -0.926 12.2-152.3-106.5 127.3 56.6 22.7 24.8 85 90 A G E -cd 63 113A 0 27,-2.6 29,-2.1 -2,-0.5 -21,-0.2 -0.864 5.7-162.0-106.1 130.3 53.2 24.4 24.1 86 91 A V E -c 64 0A 0 -23,-2.7 -21,-1.7 -2,-0.5 2,-0.5 -0.929 17.1-139.0-109.3 112.0 52.7 26.8 21.2 87 92 A P E -c 65 0A 0 0, 0.0 30,-3.2 0, 0.0 31,-0.2 -0.595 16.4-153.5 -71.2 121.6 49.6 29.0 21.5 88 93 A V E -c 66 0A 6 -23,-2.5 -21,-0.6 -2,-0.5 2,-0.3 -0.857 13.6-130.8 -97.3 122.1 48.0 29.2 18.1 89 94 A P - 0 0 17 0, 0.0 4,-0.1 0, 0.0 2,-0.1 -0.554 26.6-164.7 -74.6 132.8 46.0 32.4 17.6 90 95 A L - 0 0 67 2,-0.4 4,-0.3 -2,-0.3 5,-0.1 -0.174 43.0 -68.8 -99.8-160.2 42.5 31.8 16.3 91 96 A G S S+ 0 0 74 2,-0.1 2,-0.4 -2,-0.1 -1,-0.0 0.761 115.2 35.7 -64.9 -28.2 39.9 34.2 14.8 92 97 A R S > S+ 0 0 199 1,-0.1 3,-0.6 0, 0.0 -2,-0.4 -0.963 111.4 22.1-130.6 147.7 39.2 36.1 18.0 93 98 A L G > S- 0 0 83 -2,-0.4 3,-2.3 1,-0.2 4,-0.1 0.378 96.6-105.8 82.1 -0.5 41.3 37.3 21.0 94 99 A D G 3 S- 0 0 45 -4,-0.3 -1,-0.2 1,-0.3 -3,-0.1 0.782 75.9 -55.1 58.1 31.6 44.6 37.1 19.1 95 100 A G G <> S+ 0 0 0 -3,-0.6 4,-2.6 -7,-0.2 -1,-0.3 0.557 106.4 123.4 78.5 7.6 45.7 33.9 20.9 96 101 A L H <> S+ 0 0 49 -3,-2.3 4,-2.3 2,-0.2 5,-0.2 0.910 79.8 46.5 -65.7 -41.0 45.3 35.4 24.4 97 102 A D H > S+ 0 0 2 -5,-0.2 4,-2.6 2,-0.2 -28,-0.3 0.930 112.3 51.1 -60.8 -44.6 42.9 32.6 25.2 98 103 A S H > S+ 0 0 0 1,-0.2 4,-1.1 2,-0.2 -2,-0.2 0.922 111.1 48.8 -58.5 -45.2 45.4 30.1 23.7 99 104 A L H >X S+ 0 0 0 -4,-2.6 4,-3.1 2,-0.2 3,-0.6 0.948 113.8 42.6 -62.3 -51.6 48.2 31.5 25.8 100 105 A L H 3X S+ 0 0 3 -4,-2.3 4,-1.6 1,-0.2 -1,-0.2 0.898 111.1 57.4 -65.1 -38.6 46.4 31.5 29.1 101 106 A S H 3< S+ 0 0 0 -4,-2.6 -1,-0.2 -34,-0.3 -2,-0.2 0.750 118.1 32.7 -60.8 -27.2 45.0 28.0 28.4 102 107 A I H << S+ 0 0 0 -4,-1.1 3,-0.5 -3,-0.6 -2,-0.2 0.865 120.9 42.6 -95.9 -45.8 48.5 26.7 27.9 103 108 A V H < S+ 0 0 2 -4,-3.1 2,-1.2 1,-0.2 347,-0.3 0.847 95.5 74.6 -78.9 -31.1 50.8 28.6 30.3 104 109 A Q < + 0 0 14 -4,-1.6 473,-2.2 -5,-0.3 -1,-0.2 -0.018 61.0 157.2 -81.2 37.9 48.6 28.7 33.5 105 110 A M - 0 0 3 -2,-1.2 345,-0.3 -3,-0.5 3,-0.1 -0.383 40.4-124.9 -62.9 126.9 49.1 25.1 34.5 106 111 A P > - 0 0 47 0, 0.0 3,-1.3 0, 0.0 -1,-0.1 -0.210 49.2 -60.1 -64.6 165.9 48.5 24.6 38.2 107 112 A A T 3 S+ 0 0 91 1,-0.2 347,-0.0 3,-0.0 346,-0.0 -0.188 117.7 38.9 -51.1 132.7 51.2 23.0 40.4 108 113 A G T 3 S+ 0 0 11 -3,-0.1 -1,-0.2 442,-0.0 375,-0.1 -0.153 105.2 55.6 125.3 -36.8 52.2 19.5 39.5 109 114 A V < - 0 0 7 -3,-1.3 2,-0.2 2,-0.0 -32,-0.1 -0.891 68.7-160.6-134.1 102.8 52.3 19.4 35.6 110 115 A P - 0 0 2 0, 0.0 2,-0.4 0, 0.0 -27,-0.3 -0.517 8.0-167.1 -87.6 150.0 54.4 21.9 33.8 111 116 A V - 0 0 3 -8,-0.2 2,-0.9 -2,-0.2 -27,-0.2 -0.994 22.5-132.8-129.2 128.2 54.2 23.0 30.2 112 117 A A E -d 84 0A 0 -29,-2.7 -27,-2.6 -2,-0.4 2,-0.4 -0.693 32.4-158.7 -78.2 109.3 57.1 25.0 28.6 113 118 A T E -dE 85 448A 0 335,-2.5 335,-2.5 -2,-0.9 2,-0.2 -0.746 11.4-170.1-100.9 134.6 55.2 27.8 26.9 114 119 A V - 0 0 2 -29,-2.1 3,-0.1 -2,-0.4 325,-0.1 -0.545 39.7 -62.5-108.2 179.7 56.5 30.0 24.0 115 120 A S > - 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