==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=7-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 11-JUN-02 1LZV . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.K.TU,M.QIAN,H.AN,N.R.WADHWA,D.M.DUDA,C.YOSHIOKA,Y.PATHAK, . 256 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11762.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 165 64.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 56 21.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 10.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 12.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 5 A W 0 0 91 0, 0.0 2,-0.2 0, 0.0 7,-0.2 0.000 360.0 360.0 360.0 163.5 7.9 -1.4 11.2 2 6 A G - 0 0 6 5,-2.4 10,-0.1 2,-0.1 58,-0.1 -0.770 360.0 -82.9-169.4-146.6 5.3 -4.1 10.5 3 7 A H S S+ 0 0 26 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.303 83.6 113.0-125.7 4.7 4.2 -7.4 11.8 4 8 A G S > S- 0 0 30 3,-0.1 4,-0.8 4,-0.1 3,-0.2 0.041 85.3 -94.8 -68.0-178.3 6.8 -9.6 10.1 5 9 A K T 4 S+ 0 0 173 1,-0.2 -1,-0.1 2,-0.2 5,-0.1 0.839 122.5 41.9 -69.9 -31.1 9.5 -11.5 11.8 6 10 A H T 4 S+ 0 0 156 1,-0.1 -1,-0.2 4,-0.0 -2,-0.0 0.533 129.2 22.9 -96.5 -7.6 12.1 -8.8 11.4 7 11 A N T 4 S+ 0 0 64 -3,-0.2 -5,-2.4 -6,-0.0 -2,-0.2 0.130 93.5 132.1-142.2 18.5 10.0 -5.6 12.2 8 12 A G S >X S- 0 0 0 -4,-0.8 3,-3.1 -5,-0.2 4,-0.8 0.011 78.4 -73.4 -68.7 176.7 7.2 -7.1 14.2 9 13 A P T 34 S+ 0 0 25 0, 0.0 4,-0.4 0, 0.0 -1,-0.1 0.668 128.3 63.6 -42.9 -27.1 5.7 -6.0 17.6 10 14 A E T 34 S+ 0 0 103 1,-0.2 3,-0.2 2,-0.1 -2,-0.1 0.711 104.9 44.8 -75.7 -20.5 8.9 -7.3 19.4 11 15 A H T X> S+ 0 0 57 -3,-3.1 3,-1.9 1,-0.1 4,-0.5 0.612 88.5 88.9 -95.9 -17.6 11.1 -4.7 17.6 12 16 A W H >X S+ 0 0 3 -4,-0.8 4,-3.0 1,-0.3 3,-0.6 0.775 70.7 72.9 -53.5 -34.1 8.8 -1.7 18.0 13 17 A H H 34 S+ 0 0 69 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.729 91.4 61.1 -56.9 -20.7 10.3 -0.7 21.3 14 18 A K H <4 S+ 0 0 129 -3,-1.9 -1,-0.2 1,-0.1 -2,-0.2 0.907 117.1 24.7 -74.9 -43.7 13.4 0.5 19.5 15 19 A D H << S+ 0 0 123 -3,-0.6 -2,-0.2 -4,-0.5 -1,-0.1 0.790 134.1 38.3 -89.4 -30.2 11.7 3.2 17.3 16 20 A F >< - 0 0 59 -4,-3.0 3,-2.3 1,-0.1 -1,-0.2 -0.790 65.1-175.8-125.3 86.1 8.8 3.7 19.7 17 21 A P G > S+ 0 0 98 0, 0.0 3,-2.0 0, 0.0 -1,-0.1 0.759 78.5 74.4 -49.4 -32.7 9.9 3.6 23.3 18 22 A I G > + 0 0 56 1,-0.3 3,-2.8 2,-0.2 -5,-0.1 0.621 70.0 91.8 -61.3 -8.7 6.4 4.0 24.6 19 23 A A G < S+ 0 0 7 -3,-2.3 -1,-0.3 1,-0.3 -6,-0.1 0.782 90.4 44.0 -56.2 -26.8 6.0 0.3 23.5 20 24 A K G < S+ 0 0 146 -3,-2.0 -1,-0.3 -7,-0.1 -2,-0.2 -0.041 95.2 133.0-107.1 28.4 7.0 -0.5 27.1 21 25 A G < - 0 0 17 -3,-2.8 3,-0.4 1,-0.1 -3,-0.0 0.149 69.1-102.8 -69.0-171.0 4.7 2.2 28.5 22 26 A E S S+ 0 0 117 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.710 111.9 35.4 -89.6 -25.2 2.2 2.0 31.4 23 27 A R S S+ 0 0 49 168,-0.1 -1,-0.2 224,-0.1 2,-0.1 -0.375 80.1 151.6-128.6 58.3 -1.0 1.8 29.5 24 28 A Q - 0 0 4 -3,-0.4 220,-0.1 221,-0.3 170,-0.1 -0.447 33.3 -98.9 -84.7 160.3 -0.3 -0.2 26.4 25 29 A S S S+ 0 0 0 168,-0.4 2,-0.2 -2,-0.1 78,-0.0 -0.934 75.0 39.4-139.4 162.0 -2.8 -2.4 24.5 26 30 A P + 0 0 0 0, 0.0 218,-2.6 0, 0.0 2,-0.3 0.555 64.3 175.0 -78.3-178.2 -4.1 -4.9 23.8 27 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.5 -0.920 36.3 -97.3-143.3 166.4 -4.5 -6.8 27.0 28 32 A D E -a 104 0A 43 216,-0.4 2,-0.7 -2,-0.3 77,-0.2 -0.778 35.9-137.0 -89.7 128.8 -6.1 -10.1 28.2 29 33 A I E -a 105 0A 0 75,-3.5 77,-2.6 -2,-0.5 2,-1.0 -0.773 9.0-155.0 -92.0 116.1 -9.5 -9.6 29.8 30 34 A D >> - 0 0 62 -2,-0.7 4,-2.4 75,-0.2 3,-1.2 -0.784 1.4-162.0 -90.5 104.2 -10.0 -11.6 32.9 31 35 A T T 34 S+ 0 0 48 -2,-1.0 -1,-0.2 1,-0.3 74,-0.0 0.740 88.9 50.1 -57.5 -25.0 -13.8 -12.0 33.2 32 36 A H T 34 S+ 0 0 160 1,-0.1 -1,-0.3 -3,-0.1 -2,-0.0 0.625 115.4 39.9 -91.5 -14.3 -13.5 -13.0 36.9 33 37 A T T <4 S+ 0 0 102 -3,-1.2 -2,-0.2 2,-0.1 -1,-0.1 0.685 88.1 101.7-104.2 -24.4 -11.3 -10.0 37.9 34 38 A A S < S- 0 0 20 -4,-2.4 2,-0.4 1,-0.1 218,-0.2 -0.361 73.8-127.8 -58.4 138.3 -12.9 -7.3 35.9 35 39 A K E -c 252 0B 121 216,-2.1 218,-2.9 2,-0.0 2,-0.6 -0.764 5.3-124.6-101.0 139.4 -15.2 -5.3 38.2 36 40 A Y E -c 253 0B 91 -2,-0.4 218,-0.2 216,-0.2 220,-0.1 -0.658 25.6-166.7 -75.8 120.0 -18.8 -4.5 37.7 37 41 A D > - 0 0 33 216,-2.3 3,-1.9 -2,-0.6 -1,-0.0 -0.885 7.9-165.9-112.8 98.0 -19.1 -0.7 37.9 38 42 A P T 3 S+ 0 0 95 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.709 81.0 71.5 -55.7 -21.2 -22.8 0.2 38.3 39 43 A S T 3 + 0 0 78 -3,-0.1 2,-0.3 2,-0.0 215,-0.1 0.510 68.7 112.7 -77.5 -2.9 -22.1 3.8 37.5 40 44 A L < - 0 0 31 -3,-1.9 3,-0.1 213,-0.2 37,-0.0 -0.560 63.7-138.0 -72.9 129.5 -21.3 3.2 33.8 41 45 A K - 0 0 133 37,-1.3 39,-0.1 -2,-0.3 3,-0.1 -0.412 32.9 -89.7 -79.1 160.8 -24.0 4.7 31.6 42 46 A P - 0 0 111 0, 0.0 36,-1.2 0, 0.0 2,-0.1 -0.400 49.7 -99.2 -70.1 153.4 -25.2 2.7 28.6 43 47 A L E -D 77 0B 19 141,-0.2 2,-0.6 34,-0.2 34,-0.2 -0.472 31.8-150.6 -71.4 144.4 -23.3 3.2 25.4 44 48 A S E +D 76 0B 53 32,-2.6 32,-2.3 -2,-0.1 2,-0.5 -0.927 16.0 179.9-121.9 105.1 -24.8 5.6 22.9 45 49 A V E -D 75 0B 38 -2,-0.6 2,-0.5 30,-0.2 30,-0.2 -0.924 5.0-178.6-108.1 122.4 -24.0 4.8 19.3 46 50 A S E +D 74 0B 39 28,-2.7 28,-1.6 -2,-0.5 3,-0.2 -0.820 22.4 145.5-121.7 89.6 -25.5 7.1 16.6 47 51 A Y + 0 0 4 -2,-0.5 3,-0.3 26,-0.2 130,-0.3 0.109 37.5 105.1-112.0 22.4 -24.5 5.9 13.2 48 52 A D S S+ 0 0 92 1,-0.2 -1,-0.1 128,-0.1 25,-0.1 0.732 89.1 37.4 -75.8 -21.0 -27.7 6.8 11.2 49 53 A Q S S+ 0 0 124 23,-1.1 -1,-0.2 -3,-0.2 24,-0.2 0.358 85.6 142.1-107.0 2.9 -26.1 9.9 9.5 50 54 A A - 0 0 22 -3,-0.3 2,-0.6 22,-0.2 23,-0.1 -0.137 37.0-157.7 -47.1 131.8 -22.7 8.1 9.1 51 55 A T - 0 0 51 16,-0.3 16,-2.5 122,-0.1 2,-0.2 -0.904 3.6-160.6-120.2 101.2 -21.1 9.0 5.8 52 56 A S E +E 66 0B 2 -2,-0.6 121,-0.6 122,-0.3 14,-0.3 -0.502 14.8 171.9 -77.3 151.4 -18.5 6.5 4.6 53 57 A L E - 0 0 77 12,-3.5 118,-2.7 1,-0.4 2,-0.3 0.705 48.4 -0.4-125.0 -54.1 -16.1 7.8 2.0 54 58 A R E -EF 65 170B 92 11,-1.1 11,-3.9 116,-0.3 2,-0.4 -0.942 43.1-148.3-145.2 160.6 -13.2 5.6 1.1 55 59 A I E +EF 64 169B 0 114,-2.0 114,-2.5 -2,-0.3 2,-0.3 -0.996 27.7 177.4-129.9 134.2 -11.5 2.2 1.8 56 60 A L E -EF 63 168B 28 7,-2.3 7,-2.4 -2,-0.4 2,-0.8 -0.992 33.9-130.0-143.8 153.4 -7.7 1.9 1.5 57 61 A N E +E 62 0B 0 110,-2.9 109,-3.2 -2,-0.3 5,-0.2 -0.881 23.6 179.1 -98.9 109.4 -4.9 -0.5 2.0 58 62 A N - 0 0 53 3,-1.7 4,-0.1 -2,-0.8 -1,-0.1 0.226 55.3-101.1 -96.0 12.9 -2.3 1.3 4.1 59 63 A G S S+ 0 0 5 2,-0.5 3,-0.1 166,-0.2 106,-0.1 0.407 117.4 57.0 85.4 -3.3 0.1 -1.7 4.2 60 64 A H S S- 0 0 57 1,-0.6 2,-0.3 -58,-0.1 -1,-0.1 0.517 123.8 -32.3-128.1 -24.8 -0.9 -2.8 7.7 61 65 A A S S- 0 0 6 165,-0.1 -3,-1.7 -5,-0.1 -1,-0.6 -0.894 70.6 -87.7-172.4-167.9 -4.7 -3.3 7.2 62 66 A F E -E 57 0B 0 -2,-0.3 29,-0.4 -5,-0.2 2,-0.4 -0.995 38.0-155.0-126.6 127.4 -7.5 -1.7 5.2 63 67 A N E -E 56 0B 20 -7,-2.4 -7,-2.3 -2,-0.5 2,-0.6 -0.839 10.5-149.9-106.4 140.7 -9.3 1.3 6.6 64 68 A V E -EG 55 89B 0 25,-2.3 25,-1.4 -2,-0.4 2,-0.4 -0.940 26.2-149.1-103.1 120.1 -12.8 2.5 5.8 65 69 A E E -EG 54 88B 56 -11,-3.9 -12,-3.5 -2,-0.6 -11,-1.1 -0.774 11.1-163.2 -99.5 137.9 -12.8 6.3 6.1 66 70 A F E -E 52 0B 5 21,-2.3 2,-0.7 -2,-0.4 -14,-0.2 -0.817 31.6-101.5-115.6 155.7 -15.7 8.4 7.2 67 71 A D + 0 0 39 -16,-2.5 -16,-0.3 -2,-0.3 3,-0.3 -0.642 39.7 173.6 -74.8 112.2 -16.5 12.1 6.9 68 72 A D + 0 0 42 -2,-0.7 -1,-0.1 1,-0.2 17,-0.1 -0.022 46.6 107.9-111.4 29.0 -15.7 13.4 10.4 69 73 A S S S+ 0 0 77 56,-0.0 2,-0.3 2,-0.0 -1,-0.2 0.470 88.0 22.3 -83.0 -2.5 -16.2 17.1 9.6 70 74 A Q S S- 0 0 110 -3,-0.3 2,-1.7 3,-0.1 3,-0.4 -0.951 93.7 -88.7-153.5 171.4 -19.4 17.0 11.5 71 75 A D S S+ 0 0 90 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.564 79.4 117.3 -85.7 73.9 -21.3 15.2 14.3 72 76 A K S S+ 0 0 50 -2,-1.7 -23,-1.1 1,-0.3 2,-0.3 0.594 77.0 30.7-114.4 -17.3 -23.0 12.7 12.1 73 77 A A S S+ 0 0 5 -3,-0.4 13,-3.0 -24,-0.2 2,-0.3 -0.820 85.6 158.1-142.3 94.6 -21.6 9.3 13.3 74 78 A V E -DH 46 85B 13 -28,-1.6 -28,-2.7 -2,-0.3 2,-0.4 -0.822 35.3-147.1-126.7 164.5 -20.8 9.6 17.0 75 79 A L E +DH 45 84B 0 9,-2.5 9,-2.0 -2,-0.3 2,-0.3 -0.972 29.7 160.4-124.8 138.8 -20.3 7.6 20.2 76 80 A K E +D 44 0B 95 -32,-2.3 -32,-2.6 -2,-0.4 7,-0.1 -0.928 34.2 26.7-151.2 172.5 -21.3 8.9 23.6 77 81 A G E > S+D 43 0B 20 5,-0.4 3,-2.1 -2,-0.3 -34,-0.2 -0.267 70.5 92.2 70.5-155.2 -22.1 7.9 27.1 78 82 A G T 3 S- 0 0 7 -36,-1.2 -37,-1.3 1,-0.3 -1,-0.1 -0.522 120.2 -28.6 65.2-129.4 -20.7 4.7 28.7 79 83 A P T 3 S+ 0 0 42 0, 0.0 -1,-0.3 0, 0.0 2,-0.1 0.427 117.1 111.5 -96.2 -0.7 -17.4 5.8 30.5 80 84 A L < - 0 0 12 -3,-2.1 2,-0.5 -39,-0.1 -3,-0.2 -0.428 55.3-155.0 -77.4 146.4 -17.0 8.6 27.9 81 85 A D - 0 0 133 53,-0.1 2,-0.1 -2,-0.1 -1,-0.0 -0.987 66.7 -2.7-119.4 114.3 -17.3 12.3 28.7 82 86 A G S S- 0 0 42 -2,-0.5 2,-0.4 39,-0.1 -5,-0.4 -0.415 98.8 -48.3 99.5-177.5 -18.3 14.3 25.6 83 87 A T - 0 0 23 -2,-0.1 38,-2.7 -7,-0.1 2,-0.4 -0.808 42.0-163.9-103.9 137.7 -18.8 13.4 22.0 84 88 A Y E -HI 75 120B 4 -9,-2.0 -9,-2.5 -2,-0.4 2,-0.4 -0.975 12.9-142.4-120.5 131.2 -16.5 11.3 19.9 85 89 A R E -HI 74 119B 50 34,-2.1 34,-1.6 -2,-0.4 2,-0.4 -0.740 17.9-118.9 -95.7 140.1 -16.7 11.2 16.1 86 90 A L E + I 0 118B 1 -13,-3.0 32,-0.3 -2,-0.4 -14,-0.1 -0.605 38.8 163.4 -75.3 122.9 -16.2 8.1 14.0 87 91 A I E - 0 0 34 30,-2.9 -21,-2.3 -2,-0.4 2,-0.3 0.704 60.8 -18.6-110.6 -30.3 -13.2 8.6 11.7 88 92 A Q E -GI 65 117B 35 29,-1.3 29,-3.4 -23,-0.2 -1,-0.4 -0.983 46.0-151.8-170.7 158.6 -12.4 5.1 10.6 89 93 A F E +GI 64 116B 0 -25,-1.4 -25,-2.3 -2,-0.3 2,-0.3 -0.977 21.0 163.2-136.8 149.4 -12.7 1.4 11.3 90 94 A H E - I 0 115B 24 25,-1.7 25,-2.9 -2,-0.3 2,-0.3 -0.922 24.4-121.2-152.6 174.6 -10.4 -1.5 10.4 91 95 A F E - I 0 114B 1 -29,-0.4 2,-0.4 -2,-0.3 -29,-0.2 -0.790 2.1-149.2-124.7 168.8 -9.7 -5.1 11.3 92 96 A H E + I 0 113B 4 21,-1.0 21,-2.0 -2,-0.3 2,-0.3 -0.996 30.0 168.7-135.1 125.7 -7.0 -7.4 12.7 93 97 A W E - I 0 112B 0 -2,-0.4 146,-1.2 19,-0.2 145,-0.8 -0.932 23.0-126.4-141.0 164.7 -7.0 -11.0 11.6 94 98 A G - 0 0 0 17,-1.3 6,-0.1 5,-0.8 3,-0.1 -0.419 27.1-114.1-105.4-180.0 -4.9 -14.1 11.7 95 99 A S S S+ 0 0 43 142,-0.1 2,-0.3 -2,-0.1 5,-0.1 0.611 106.8 32.7 -85.3 -14.2 -3.5 -16.7 9.2 96 100 A L S > S- 0 0 112 3,-0.2 3,-1.4 15,-0.1 -2,-0.3 -0.932 88.0-113.0-138.3 159.0 -5.7 -19.2 11.0 97 101 A D T 3 S+ 0 0 69 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.733 108.7 70.0 -65.6 -23.0 -9.1 -19.1 12.7 98 102 A G T 3 S+ 0 0 57 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.444 109.2 24.0 -76.7 2.0 -7.6 -19.8 16.1 99 103 A Q < + 0 0 53 -3,-1.4 -5,-0.8 12,-0.1 -3,-0.2 -0.977 65.7 98.5-157.2 166.9 -5.9 -16.4 16.2 100 104 A G + 0 0 1 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 -0.068 56.4 107.0 142.0 -38.3 -6.1 -12.9 14.9 101 105 A S - 0 0 3 9,-2.2 -1,-0.6 11,-0.3 139,-0.1 -0.263 56.0-148.7 -68.1 157.7 -7.9 -10.8 17.5 102 106 A E S S+ 0 0 2 -10,-0.1 2,-0.1 -3,-0.1 -1,-0.1 0.876 81.8 51.9 -92.7 -50.4 -5.8 -8.4 19.6 103 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.483 75.4-155.6 -82.3 157.7 -7.6 -8.5 22.9 104 108 A T E -a 28 0A 9 -77,-1.2 -75,-3.5 -2,-0.1 2,-0.6 -0.959 11.0-138.1-133.9 150.8 -8.3 -11.9 24.4 105 109 A V E > S-aB 29 108A 19 3,-1.7 3,-1.9 -2,-0.3 -75,-0.2 -0.935 89.4 -22.4-115.2 110.9 -11.0 -13.0 26.9 106 110 A D T 3 S- 0 0 68 -77,-2.6 -1,-0.2 -2,-0.6 -76,-0.1 0.870 128.6 -54.4 56.6 36.4 -9.7 -15.3 29.6 107 111 A K T 3 S+ 0 0 154 1,-0.3 2,-0.4 -78,-0.2 -1,-0.3 0.454 104.5 138.5 78.1 3.8 -6.9 -16.0 27.1 108 112 A K B < -B 105 0A 118 -3,-1.9 -3,-1.7 -9,-0.0 2,-0.4 -0.675 41.2-150.4 -83.0 132.3 -9.2 -17.0 24.3 109 113 A K - 0 0 95 -2,-0.4 2,-0.2 -11,-0.2 -5,-0.1 -0.853 6.2-149.6-103.6 134.7 -8.3 -15.7 20.9 110 114 A Y - 0 0 31 -7,-0.4 -9,-2.2 -2,-0.4 34,-0.2 -0.528 29.9-106.2 -96.9 168.4 -10.9 -14.9 18.2 111 115 A A S S- 0 0 3 32,-0.9 -17,-1.3 -11,-0.2 2,-0.3 0.750 95.0 -16.5 -65.1 -24.3 -10.4 -15.1 14.4 112 116 A A E -IJ 93 143B 1 31,-1.3 31,-2.6 -19,-0.2 2,-0.4 -0.979 56.9-133.8-169.9 170.0 -10.3 -11.3 14.2 113 117 A E E -IJ 92 142B 0 -21,-2.0 -21,-1.0 -13,-0.3 2,-0.3 -0.975 14.6-146.2-143.3 123.4 -11.1 -8.0 16.0 114 118 A L E -IJ 91 141B 0 27,-3.4 27,-2.2 -2,-0.4 2,-0.5 -0.695 11.4-160.2 -90.0 138.8 -12.9 -5.0 14.5 115 119 A H E -IJ 90 140B 3 -25,-2.9 -25,-1.7 -2,-0.3 2,-0.7 -0.972 7.3-168.7-124.6 117.6 -11.8 -1.5 15.7 116 120 A L E -IJ 89 139B 0 23,-2.2 23,-2.7 -2,-0.5 2,-0.5 -0.925 20.0-153.2-104.6 111.8 -14.1 1.5 15.2 117 121 A V E +IJ 88 138B 8 -29,-3.4 -30,-2.9 -2,-0.7 -29,-1.3 -0.776 18.8 172.1 -97.6 128.0 -12.0 4.6 16.0 118 122 A H E -IJ 86 137B 0 19,-1.6 19,-2.6 -2,-0.5 2,-0.4 -0.932 17.6-145.5-127.7 150.4 -13.5 7.9 17.3 119 123 A W E -IJ 85 136B 7 -34,-1.6 -34,-2.1 -2,-0.3 2,-0.5 -0.914 29.3-102.0-119.7 147.3 -11.8 11.1 18.6 120 124 A N E > -I 84 0B 3 15,-3.4 3,-2.1 -2,-0.4 -36,-0.2 -0.512 27.0-147.9 -66.5 114.2 -13.0 13.5 21.3 121 125 A T G > S+ 0 0 37 -38,-2.7 3,-2.2 -2,-0.5 -1,-0.2 0.751 89.2 76.2 -57.1 -27.4 -14.5 16.6 19.5 122 127 A K G 3 S+ 0 0 139 -39,-0.3 -1,-0.3 1,-0.3 -2,-0.1 0.678 90.6 60.5 -61.0 -11.4 -13.4 19.0 22.2 123 128 A Y G < S- 0 0 52 -3,-2.1 2,-2.0 12,-0.1 -1,-0.3 0.241 101.6-131.7 -99.8 12.2 -9.9 18.7 20.7 124 129 A G S < S+ 0 0 61 -3,-2.2 2,-0.3 4,-0.1 -3,-0.1 -0.099 73.6 17.3 71.3 -45.3 -10.8 20.0 17.2 125 130 A D S >> S- 0 0 64 -2,-2.0 4,-2.1 -5,-0.2 3,-0.5 -0.980 78.0-103.0-155.1 166.8 -9.2 17.2 15.1 126 131 A F H 3> S+ 0 0 71 -2,-0.3 4,-2.0 1,-0.2 5,-0.2 0.871 114.8 59.6 -57.8 -41.9 -7.8 13.7 15.2 127 132 A G H 34 S+ 0 0 40 1,-0.2 -1,-0.2 2,-0.2 -3,-0.1 0.820 111.7 37.8 -60.1 -35.2 -4.2 15.0 15.2 128 133 A K H X4 S+ 0 0 121 -3,-0.5 3,-1.3 -5,-0.2 -1,-0.2 0.831 111.9 60.2 -85.0 -32.7 -4.6 16.9 18.4 129 134 A A H >< S+ 0 0 0 -4,-2.1 3,-1.9 1,-0.3 6,-0.3 0.855 94.4 60.9 -62.7 -39.0 -6.8 14.2 20.0 130 135 A V T 3< S+ 0 0 18 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.1 0.560 97.6 63.6 -68.2 -3.6 -4.3 11.4 19.9 131 136 A Q T < S+ 0 0 137 -3,-1.3 -1,-0.3 -5,-0.2 -2,-0.2 0.242 91.9 80.2-102.6 12.0 -2.1 13.6 22.1 132 137 A Q S X S- 0 0 65 -3,-1.9 3,-1.8 69,-0.1 4,-0.3 -0.922 81.4-126.6-121.8 145.6 -4.5 13.5 25.0 133 138 A P T 3 S+ 0 0 82 0, 0.0 58,-0.1 0, 0.0 3,-0.1 0.768 116.7 30.0 -59.0 -22.9 -5.1 10.8 27.6 134 139 A D T 3 S+ 0 0 43 1,-0.1 -53,-0.1 -5,-0.1 68,-0.1 -0.027 87.9 112.2-126.1 31.6 -8.8 10.9 26.7 135 140 A G S < S+ 0 0 0 -3,-1.8 -15,-3.4 -6,-0.3 2,-0.3 0.768 72.6 41.8 -77.5 -28.5 -8.6 11.9 23.0 136 141 A L E -Jk 119 202B 0 65,-2.6 67,-2.2 -4,-0.3 2,-0.4 -0.901 54.2-163.6-125.6 154.7 -9.8 8.6 21.4 137 142 A A E -Jk 118 203B 0 -19,-2.6 -19,-1.6 -2,-0.3 2,-0.5 -0.959 13.6-166.1-133.0 110.2 -12.5 6.1 22.0 138 143 A V E -Jk 117 204B 3 65,-1.4 67,-2.0 -2,-0.4 2,-0.7 -0.879 9.6-150.4-104.6 128.5 -12.1 2.7 20.2 139 144 A L E -Jk 116 205B 1 -23,-2.7 -23,-2.2 -2,-0.5 2,-0.5 -0.863 16.6-158.8 -95.9 114.8 -15.0 0.3 19.9 140 145 A G E +Jk 115 206B 0 65,-3.5 67,-2.9 -2,-0.7 2,-0.4 -0.852 12.8 179.7-102.9 126.6 -13.7 -3.2 19.8 141 146 A I E -J 114 0B 0 -27,-2.2 -27,-3.4 -2,-0.5 2,-0.2 -0.986 19.5-138.7-125.1 126.2 -15.8 -6.1 18.4 142 147 A F E -J 113 0B 0 -2,-0.4 69,-2.7 65,-0.4 2,-0.4 -0.510 12.3-149.9 -81.3 151.2 -14.6 -9.7 18.2 143 148 A L E -Jl 112 211B 1 -31,-2.6 -31,-1.3 67,-0.2 -32,-0.9 -0.983 11.7-173.6-124.4 133.1 -15.3 -11.9 15.2 144 149 A K E - l 0 212B 103 67,-2.3 69,-2.0 -2,-0.4 2,-0.3 -0.920 31.3-106.1-122.9 150.0 -15.7 -15.6 15.3 145 150 A V E S+ l 0 213B 49 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.610 75.5 83.3 -79.8 130.8 -16.1 -18.0 12.3 146 151 A G S S+ 0 0 44 67,-3.3 69,-0.5 -2,-0.3 2,-0.1 -0.665 77.9 23.1 179.6-119.2 -19.5 -19.4 11.7 147 152 A S S S- 0 0 93 -2,-0.2 -1,-0.2 67,-0.1 2,-0.0 -0.468 85.6-101.4 -73.7 145.1 -22.5 -17.9 9.9 148 153 A A - 0 0 55 65,-0.3 65,-0.2 -2,-0.1 -1,-0.1 -0.316 25.6-128.7 -66.3 147.3 -21.8 -15.2 7.3 149 154 A K >> - 0 0 48 1,-0.2 3,-1.8 65,-0.1 4,-0.8 -0.871 15.1-159.1 -99.7 104.6 -22.4 -11.6 8.3 150 155 A P G >4 S+ 0 0 109 0, 0.0 3,-1.2 0, 0.0 4,-0.4 0.911 88.1 56.3 -48.7 -50.4 -24.6 -10.1 5.5 151 156 A G G 34 S+ 0 0 34 27,-0.3 27,-0.2 1,-0.2 28,-0.1 0.551 103.5 54.5 -63.0 -9.8 -23.7 -6.5 6.4 152 157 A L G X> S+ 0 0 3 -3,-1.8 4,-1.4 26,-0.1 3,-1.4 0.635 84.4 84.2 -97.1 -18.4 -20.0 -7.2 5.9 153 158 A Q H S+ 0 0 124 -4,-0.4 4,-0.5 1,-0.2 -1,-0.3 0.838 106.7 48.1 -61.0 -28.6 -20.1 -5.2 0.7 155 160 A V H X> S+ 0 0 0 -3,-1.4 3,-0.8 2,-0.2 4,-0.7 0.908 109.3 48.5 -77.3 -45.6 -16.6 -4.8 2.2 156 161 A V H 3< S+ 0 0 0 -4,-1.4 3,-0.4 1,-0.2 4,-0.3 0.815 104.4 62.5 -67.2 -28.3 -15.2 -8.2 1.2 157 162 A D H 3< S+ 0 0 88 -4,-2.1 3,-0.3 1,-0.2 -1,-0.2 0.763 106.6 42.9 -69.0 -25.1 -16.4 -7.7 -2.4 158 163 A V H X< S+ 0 0 38 -3,-0.8 3,-2.0 -4,-0.5 4,-0.4 0.541 84.9 93.2 -97.1 -8.7 -14.2 -4.6 -2.9 159 164 A L G >< S+ 0 0 6 -4,-0.7 3,-1.2 -3,-0.4 -1,-0.2 0.778 75.9 69.5 -54.3 -25.4 -11.1 -6.0 -1.3 160 165 A D G > S+ 0 0 122 -4,-0.3 3,-0.7 -3,-0.3 -1,-0.3 0.840 96.2 51.9 -62.3 -32.8 -10.1 -7.1 -4.8 161 166 A S G < S+ 0 0 61 -3,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.457 112.4 42.5 -86.4 -2.4 -9.5 -3.5 -5.8 162 167 A I G < S+ 0 0 0 -3,-1.2 -1,-0.2 -4,-0.4 63,-0.2 -0.154 71.8 135.7-132.1 38.0 -7.2 -2.5 -2.9 163 168 A K < + 0 0 88 -3,-0.7 62,-2.7 61,-0.1 2,-0.2 0.882 61.9 50.6 -52.7 -47.2 -5.1 -5.7 -2.9 164 169 A T S > S- 0 0 14 60,-0.2 3,-1.8 1,-0.1 -107,-0.3 -0.564 98.2 -82.7-102.0 161.8 -1.8 -3.9 -2.5 165 170 A K B 3 S+o 228 0C 97 62,-2.7 64,-0.5 1,-0.2 -107,-0.2 -0.327 113.2 25.3 -59.2 129.8 -0.4 -1.2 -0.3 166 171 A G T 3 S+ 0 0 60 -109,-3.2 -1,-0.2 1,-0.4 -108,-0.1 0.060 89.9 124.7 104.3 -24.4 -1.3 2.3 -1.3 167 172 A K < + 0 0 77 -3,-1.8 -110,-2.9 -5,-0.1 -1,-0.4 -0.385 32.3 174.3 -72.2 146.6 -4.5 1.4 -3.2 168 173 A S E -F 56 0B 54 -112,-0.2 2,-0.3 -7,-0.2 -112,-0.2 -0.972 10.5-163.4-147.3 156.5 -7.8 3.0 -2.3 169 174 A A E -F 55 0B 23 -114,-2.5 -114,-2.0 -2,-0.3 2,-0.0 -0.993 34.1 -95.5-144.7 149.1 -11.3 2.9 -3.7 170 175 A D E +F 54 0B 149 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.2 -0.405 41.8 178.8 -61.5 137.8 -14.4 5.0 -3.4 171 176 A F + 0 0 13 -118,-2.7 3,-0.3 -106,-0.1 2,-0.2 -0.624 10.4 166.5-146.7 81.3 -16.6 3.4 -0.8 172 177 A T + 0 0 87 1,-0.2 -119,-0.2 -2,-0.2 -121,-0.1 -0.645 51.6 22.1-101.8 156.7 -19.8 5.4 -0.3 173 178 A N S S+ 0 0 138 -121,-0.6 2,-0.5 -2,-0.2 -1,-0.2 0.865 71.7 153.8 61.3 43.1 -23.0 4.6 1.5 174 179 A F - 0 0 7 -3,-0.3 -122,-0.3 -20,-0.0 -1,-0.2 -0.888 35.7-145.1-101.2 131.5 -21.7 1.9 3.8 175 180 A D > - 0 0 66 -2,-0.5 3,-2.0 1,-0.1 4,-0.1 -0.826 8.3-164.9-101.0 104.2 -23.7 1.6 7.0 176 181 A P G > S+ 0 0 0 0, 0.0 3,-1.9 0, 0.0 4,-0.5 0.658 79.9 81.8 -59.5 -15.6 -21.5 0.6 10.0 177 182 A R G > S+ 0 0 123 -130,-0.3 3,-0.9 1,-0.3 -26,-0.1 0.779 79.0 69.4 -62.0 -23.4 -24.6 -0.3 12.0 178 183 A G G < S+ 0 0 30 -3,-2.0 -27,-0.3 1,-0.2 -1,-0.3 0.612 93.7 55.6 -71.0 -10.9 -24.5 -3.7 10.1 179 184 A L G < S+ 0 0 0 -3,-1.9 -1,-0.2 -4,-0.1 -2,-0.2 0.610 84.5 103.6 -96.3 -14.0 -21.4 -4.7 12.0 180 185 A L < - 0 0 31 -3,-0.9 4,-0.1 -4,-0.5 2,-0.0 -0.337 68.8-123.0 -72.8 147.7 -22.7 -4.3 15.5 181 186 A P - 0 0 11 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.282 29.9-103.8 -79.4 175.0 -23.7 -7.3 17.7 182 187 A E S S+ 0 0 185 -2,-0.0 2,-0.2 2,-0.0 -2,-0.1 0.918 102.7 46.7 -66.3 -45.2 -27.2 -7.5 19.3 183 188 A S - 0 0 30 1,-0.1 26,-0.2 2,-0.1 24,-0.0 -0.603 62.7-155.2 -99.6 161.3 -26.1 -6.5 22.8 184 189 A L + 0 0 62 -2,-0.2 -141,-0.2 -4,-0.1 -1,-0.1 0.105 42.8 137.7-120.7 19.0 -23.8 -3.7 23.9 185 190 A D + 0 0 48 22,-0.1 23,-2.3 -143,-0.1 24,-0.5 -0.424 34.7 171.8 -63.5 143.9 -22.5 -5.0 27.2 186 191 A Y E -M 207 0B 2 21,-0.3 68,-2.5 22,-0.1 2,-0.3 -0.934 38.4-128.8-151.6 172.1 -18.8 -4.1 27.4 187 192 A W E -MN 206 253B 13 19,-2.2 19,-2.6 -2,-0.3 2,-0.3 -0.890 30.1-167.2-118.7 150.0 -15.6 -3.9 29.3 188 193 A T E +MN 205 252B 9 64,-2.3 64,-2.5 -2,-0.3 17,-0.2 -1.000 16.4 151.9-144.4 145.5 -13.6 -0.7 29.4 189 194 A Y E -M 204 0B 5 15,-1.3 15,-2.8 -2,-0.3 2,-0.4 -0.971 46.7 -91.8-162.8 159.6 -10.2 0.4 30.4 190 195 A P E +M 203 0B 54 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.671 61.1 134.7 -82.7 126.9 -7.6 3.0 29.5 191 196 A G E -M 202 0B 0 11,-3.8 11,-1.6 -2,-0.4 2,-0.2 -0.465 41.5-100.0-142.3-146.3 -5.1 2.0 26.8 192 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 2,-0.1 -0.793 44.9 -73.4-140.7-179.6 -3.2 3.0 23.6 193 198 A L - 0 0 31 6,-1.6 -168,-0.4 -2,-0.2 9,-0.1 -0.498 39.5-135.0 -74.5 153.1 -3.3 2.5 19.9 194 199 A T S S+ 0 0 6 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.412 85.8 51.6 -94.3 2.8 -2.2 -1.1 19.0 195 200 A T S > S- 0 0 40 4,-0.1 3,-2.2 46,-0.0 4,-0.3 -0.961 101.9 -46.3-133.2 151.2 0.1 0.1 16.1 196 201 A P T 3 S+ 0 0 12 0, 0.0 -2,-0.1 0, 0.0 -1,-0.0 -0.177 124.1 42.0 -50.6 148.9 2.9 2.7 16.2 197 202 A P T 3 S- 0 0 64 0, 0.0 -179,-0.1 0, 0.0 -178,-0.0 -0.991 86.7-166.6 -64.3 -0.4 3.0 5.6 17.3 198 203 A L < - 0 0 0 -3,-2.2 -173,-0.1 1,-0.2 2,-0.0 0.834 14.4-170.8 53.8 37.8 1.2 3.5 19.9 199 204 A L - 0 0 40 -4,-0.3 2,-1.6 -7,-0.1 -6,-1.6 -0.315 27.7-129.1 -65.2 140.7 0.0 6.6 21.7 200 205 A E S S+ 0 0 46 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.453 75.4 111.0 -89.0 65.5 -1.6 6.1 25.1 201 206 A C + 0 0 1 -2,-1.6 -65,-2.6 -67,-0.1 2,-0.4 0.085 49.1 108.7-123.0 18.0 -4.7 8.3 24.3 202 207 A V E -kM 136 191B 0 -11,-1.6 -11,-3.8 -3,-0.2 2,-0.7 -0.857 50.2-159.4-117.0 140.0 -7.4 5.7 24.1 203 208 A T E -kM 137 190B 27 -67,-2.2 -65,-1.4 -2,-0.4 2,-0.3 -0.945 32.6-143.4-103.4 111.4 -10.4 4.7 26.2 204 209 A W E -kM 138 189B 2 -15,-2.8 -15,-1.3 -2,-0.7 2,-0.4 -0.631 19.7-174.1 -84.8 138.4 -11.1 1.1 25.1 205 210 A I E -kM 139 188B 0 -67,-2.0 -65,-3.5 -2,-0.3 2,-0.6 -0.932 7.7-174.0-131.9 101.8 -14.6 -0.2 24.9 206 211 A V E -kM 140 187B 0 -19,-2.6 -19,-2.2 -2,-0.4 2,-0.3 -0.894 20.3-132.4-105.2 122.2 -14.7 -4.0 24.1 207 212 A L E - M 0 186B 0 -67,-2.9 -65,-0.4 -2,-0.6 -21,-0.3 -0.523 2.9-146.9 -74.7 133.9 -18.0 -5.6 23.4 208 213 A K S S+ 0 0 73 -23,-2.3 -1,-0.1 -2,-0.3 -22,-0.1 0.889 83.3 70.3 -63.9 -41.8 -18.7 -8.8 25.2 209 214 A E S S- 0 0 54 -24,-0.5 -67,-0.1 -26,-0.2 -2,-0.1 -0.679 74.2-153.1 -86.1 115.3 -20.8 -10.2 22.3 210 215 A P - 0 0 34 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.370 12.3-125.9 -82.0 166.6 -18.8 -11.2 19.2 211 216 A I E -l 143 0B 7 -69,-2.7 -67,-2.3 -30,-0.1 2,-0.4 -0.775 19.8-123.2-108.3 157.8 -20.2 -11.2 15.7 212 217 A S E +l 144 0B 30 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.828 26.9 177.2-104.2 139.8 -20.2 -14.2 13.3 213 218 A V E -l 145 0B 0 -69,-2.0 -67,-3.3 -2,-0.4 -65,-0.3 -0.906 32.2-104.1-132.1 159.9 -18.7 -14.1 9.8 214 219 A S > - 0 0 7 -2,-0.3 4,-2.0 -69,-0.2 3,-0.3 -0.475 25.2-116.6 -86.0 158.8 -18.4 -17.0 7.3 215 220 A S H > S+ 0 0 50 -69,-0.5 4,-1.6 1,-0.2 -1,-0.1 0.872 118.5 54.1 -58.3 -37.6 -15.1 -18.9 6.6 216 221 A E H > S+ 0 0 133 2,-0.2 4,-1.0 1,-0.2 -1,-0.2 0.836 106.7 53.2 -66.5 -33.1 -15.3 -17.5 3.0 217 222 A Q H >> S+ 0 0 2 -3,-0.3 3,-0.9 2,-0.2 4,-0.6 0.974 111.9 40.1 -67.8 -55.8 -15.6 -14.0 4.3 218 223 A V H >X S+ 0 0 3 -4,-2.0 4,-1.1 1,-0.3 3,-0.8 0.799 107.4 68.2 -63.0 -27.3 -12.5 -14.0 6.6 219 224 A L H 3< S+ 0 0 60 -4,-1.6 3,-0.4 -5,-0.3 4,-0.3 0.867 94.8 54.0 -60.0 -38.6 -10.7 -15.9 3.9 220 225 A K H X< S+ 0 0 56 -4,-1.0 3,-0.6 -3,-0.9 -1,-0.3 0.712 98.6 63.0 -72.1 -18.3 -10.8 -12.9 1.6 221 226 A F H X< S+ 0 0 1 -3,-0.8 3,-1.2 -4,-0.6 -1,-0.2 0.865 100.2 56.0 -68.5 -37.2 -9.1 -10.8 4.2 222 227 A R T 3< S+ 0 0 34 -4,-1.1 -1,-0.2 -3,-0.4 -2,-0.2 0.563 91.8 69.0 -73.0 -11.8 -6.2 -13.1 3.9 223 228 A K T < S+ 0 0 125 -3,-0.6 -1,-0.2 -4,-0.3 -2,-0.1 0.475 79.6 104.6 -87.7 0.1 -5.7 -12.6 0.2 224 229 A L < - 0 0 2 -3,-1.2 12,-3.3 12,-0.3 2,-0.4 -0.327 66.5-128.4 -75.6 160.9 -4.6 -9.0 0.8 225 230 A N B -P 235 0D 6 -62,-2.7 10,-0.2 10,-0.3 -166,-0.2 -0.887 14.5-156.8-116.8 145.0 -1.0 -7.9 0.4 226 231 A F S S+ 0 0 23 8,-3.0 -1,-0.1 -2,-0.4 9,-0.1 0.789 80.4 77.8 -80.5 -32.4 1.3 -6.0 2.8 227 232 A N S S- 0 0 9 7,-0.5 -62,-2.7 5,-0.2 -2,-0.1 -0.258 85.8-109.3 -77.0 162.8 3.5 -5.0 -0.2 228 233 A G B -o 165 0C 7 -64,-0.3 -62,-0.1 1,-0.1 -1,-0.1 -0.429 48.2 -84.5 -86.3 166.9 2.8 -2.4 -2.9 229 234 A E S S+ 0 0 148 -64,-0.5 -1,-0.1 1,-0.2 4,-0.1 0.619 127.3 46.9 -47.4 -15.6 1.9 -3.2 -6.5 230 235 A G S S+ 0 0 71 2,-0.1 -1,-0.2 3,-0.0 3,-0.1 0.925 93.3 78.5 -93.3 -55.3 5.6 -3.6 -7.2 231 236 A E S S- 0 0 103 1,-0.1 3,-0.1 -3,-0.1 2,-0.1 0.175 93.1 -77.7 -51.3 167.8 7.2 -5.7 -4.5 232 237 A P - 0 0 113 0, 0.0 -5,-0.2 0, 0.0 -1,-0.1 -0.414 64.7 -85.2 -68.1 146.0 7.1 -9.5 -4.1 233 238 A E + 0 0 120 -3,-0.1 2,-0.4 -2,-0.1 -8,-0.1 -0.314 48.3 176.8 -60.7 127.7 3.8 -10.8 -2.8 234 239 A E - 0 0 111 -2,-0.1 -8,-3.0 -3,-0.1 -7,-0.5 -0.910 28.7-130.6-133.0 98.9 3.6 -10.8 1.0 235 240 A L B -P 225 0D 87 -2,-0.4 2,-1.1 -10,-0.2 -10,-0.3 -0.208 15.9-122.7 -55.3 139.6 0.2 -11.9 2.3 236 241 A M + 0 0 0 -12,-3.3 -12,-0.3 -15,-0.2 2,-0.3 -0.723 59.3 129.1 -88.0 96.6 -1.5 -9.7 4.9 237 242 A V + 0 0 33 -2,-1.1 -143,-0.2 1,-0.1 -142,-0.1 -0.968 53.4 25.6-145.7 158.5 -2.2 -12.0 7.8 238 243 A D + 0 0 38 -145,-0.8 2,-0.5 -2,-0.3 -144,-0.2 0.900 62.9 157.5 53.0 46.9 -1.6 -11.9 11.6 239 244 A N + 0 0 1 -146,-1.2 2,-0.3 -3,-0.1 -1,-0.2 -0.286 36.4 112.2 -94.0 46.7 -1.4 -8.1 11.8 240 245 A W - 0 0 49 -2,-0.5 -139,-0.1 -147,-0.1 -138,-0.1 -0.879 63.7-127.3-120.7 152.4 -2.3 -8.2 15.5 241 246 A R - 0 0 5 -2,-0.3 3,-0.1 -141,-0.1 -141,-0.1 -0.757 29.2-112.0 -99.6 145.3 -0.3 -7.3 18.6 242 247 A P - 0 0 60 0, 0.0 -140,-0.1 0, 0.0 -1,-0.1 -0.346 46.2 -80.3 -71.2 155.6 0.2 -9.6 21.5 243 248 A A - 0 0 51 -216,-0.1 -216,-0.3 1,-0.1 -218,-0.1 -0.182 47.1-145.0 -55.2 145.7 -1.4 -8.9 24.9 244 249 A Q - 0 0 42 -218,-2.6 -216,-0.4 -220,-0.1 -1,-0.1 -0.798 31.1 -80.8-113.6 156.8 0.5 -6.4 27.1 245 250 A P - 0 0 80 0, 0.0 -221,-0.3 0, 0.0 3,-0.1 -0.285 30.8-140.1 -56.3 136.8 0.9 -6.4 30.9 246 251 A L + 0 0 60 1,-0.2 3,-0.0 -223,-0.1 -219,-0.0 0.795 37.0 175.8 -69.3 -27.2 -2.1 -4.9 32.6 247 252 A K - 0 0 94 1,-0.2 2,-1.0 -224,-0.0 -1,-0.2 -0.313 63.7 -14.7 57.9-134.7 0.2 -3.1 35.0 248 253 A N S S+ 0 0 165 -226,-0.3 2,-0.3 -3,-0.1 -1,-0.2 -0.556 107.9 108.6-101.4 69.7 -1.7 -0.8 37.4 249 254 A R - 0 0 34 -2,-1.0 2,-0.4 -3,-0.0 -3,-0.0 -0.943 53.3-144.5-137.7 157.0 -5.0 -0.7 35.6 250 255 A Q - 0 0 107 -2,-0.3 2,-0.6 -216,-0.0 -216,-0.1 -0.984 12.4-135.2-128.7 137.2 -8.4 -2.1 36.3 251 256 A I - 0 0 10 -2,-0.4 -216,-2.1 -62,-0.1 2,-0.3 -0.814 20.5-154.0 -94.9 122.2 -10.9 -3.4 33.8 252 257 A K E -cN 35 188B 60 -64,-2.5 -64,-2.3 -2,-0.6 2,-0.4 -0.685 1.8-153.9 -95.0 146.9 -14.5 -2.3 34.3 253 258 A A E -cN 36 187B 6 -218,-2.9 -216,-2.3 -2,-0.3 -66,-0.2 -0.947 12.5-154.4-119.8 142.4 -17.6 -4.2 33.2 254 259 A S S S+ 0 0 28 -68,-2.5 2,-0.3 -2,-0.4 -67,-0.1 0.283 81.8 46.3 -94.3 7.0 -21.0 -2.6 32.4 255 260 A F 0 0 47 -69,-0.3 -218,-0.1 1,-0.1 -2,-0.1 -0.886 360.0 360.0-140.8 170.9 -22.7 -5.9 33.1 256 261 A K 0 0 205 -2,-0.3 -1,-0.1 -220,-0.1 -2,-0.1 0.179 360.0 360.0-143.0 360.0 -22.7 -8.6 35.8