==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-MAY-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/ANTIBIOTIC 15-MAR-10 3M6H . COMPND 2 MOLECULE: BETA-LACTAMASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR L.W.TREMBLAY . 266 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10766.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 178 66.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 35 13.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 4 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 36 13.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 32.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 0 0 0 2 3 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 1 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 43 A D > 0 0 125 0, 0.0 4,-1.9 0, 0.0 3,-0.0 0.000 360.0 360.0 360.0 125.1 -31.8 9.6 -8.5 2 44 A L H > + 0 0 47 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.891 360.0 51.4 -64.3 -43.8 -29.9 7.4 -6.0 3 45 A A H > S+ 0 0 49 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.868 109.6 52.6 -59.2 -40.3 -31.0 4.0 -7.3 4 46 A D H > S+ 0 0 93 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.899 108.3 50.2 -60.2 -45.5 -29.9 5.2 -10.8 5 47 A R H X S+ 0 0 130 -4,-1.9 4,-2.0 2,-0.2 -2,-0.2 0.914 110.3 49.0 -60.3 -46.1 -26.4 6.2 -9.4 6 48 A F H X S+ 0 0 2 -4,-2.3 4,-1.8 1,-0.2 -2,-0.2 0.896 111.4 50.6 -62.8 -39.5 -26.0 2.8 -7.8 7 49 A A H X S+ 0 0 21 -4,-2.2 4,-2.1 2,-0.2 -2,-0.2 0.890 106.7 54.2 -64.3 -39.4 -27.0 1.1 -11.1 8 50 A E H X S+ 0 0 62 -4,-2.4 4,-2.4 1,-0.2 -2,-0.2 0.922 108.4 50.5 -57.6 -42.5 -24.5 3.2 -13.0 9 51 A L H X S+ 0 0 7 -4,-2.0 4,-1.8 2,-0.2 6,-0.2 0.862 106.5 53.9 -65.5 -38.2 -21.8 1.9 -10.5 10 52 A E H <>S+ 0 0 17 -4,-1.8 5,-2.3 2,-0.2 4,-0.4 0.923 111.8 44.5 -62.0 -45.2 -22.8 -1.7 -11.1 11 53 A R H ><5S+ 0 0 176 -4,-2.1 3,-0.7 3,-0.2 -2,-0.2 0.905 111.7 54.6 -63.1 -42.1 -22.4 -1.3 -14.9 12 54 A R H 3<5S+ 0 0 143 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.862 121.7 27.8 -57.2 -40.4 -19.1 0.6 -14.3 13 55 A Y T 3<5S- 0 0 15 -4,-1.8 -1,-0.2 -5,-0.1 -2,-0.2 0.222 102.9-120.8-110.2 12.3 -17.6 -2.3 -12.2 14 56 A D T < 5S+ 0 0 97 -3,-0.7 227,-0.4 -4,-0.4 2,-0.2 0.922 72.5 137.4 43.4 50.1 -19.5 -5.2 -13.7 15 57 A A < - 0 0 15 -5,-2.3 2,-0.5 -6,-0.2 224,-0.2 -0.730 63.4-128.9-124.3 164.6 -20.7 -5.7 -10.1 16 58 A R E -A 238 0A 64 222,-2.6 222,-1.6 -2,-0.2 2,-0.4 -0.979 35.6-162.7-110.3 131.9 -23.7 -6.5 -8.0 17 59 A L E -A 237 0A 0 -2,-0.5 2,-0.4 220,-0.2 220,-0.2 -0.955 13.1-168.4-124.7 133.9 -24.0 -3.9 -5.2 18 60 A G E +A 236 0A 0 218,-3.4 218,-2.4 -2,-0.4 2,-0.4 -0.976 10.0 177.1-122.5 133.3 -25.9 -3.9 -2.0 19 61 A V E +AB 235 32A 0 13,-2.6 13,-2.4 -2,-0.4 2,-0.3 -0.999 4.8 170.5-133.8 133.4 -26.5 -0.8 0.2 20 62 A Y E +AB 234 31A 21 214,-2.0 214,-2.3 -2,-0.4 11,-0.2 -0.949 8.7 173.1-141.5 134.0 -28.4 -0.2 3.4 21 63 A V E - B 0 30A 0 9,-2.2 9,-2.3 -2,-0.3 212,-0.2 -0.981 36.5-124.7-126.2 116.4 -28.5 2.7 5.8 22 64 A P - 0 0 5 0, 0.0 210,-0.2 0, 0.0 5,-0.1 -0.261 31.9 -99.3 -59.1 147.8 -31.2 2.3 8.6 23 65 A A - 0 0 53 6,-0.1 5,-0.2 1,-0.1 2,-0.2 -0.294 42.4-173.6 -58.4 147.1 -33.8 5.0 8.9 24 66 A T - 0 0 52 3,-2.3 5,-0.1 207,-0.0 -1,-0.1 -0.533 47.3 -63.2-121.0-163.6 -33.3 7.7 11.6 25 67 A G S S+ 0 0 82 -2,-0.2 -2,-0.0 1,-0.2 3,-0.0 0.930 130.2 3.1 -47.5 -58.3 -35.4 10.5 13.0 26 68 A T S S+ 0 0 143 2,-0.1 2,-0.5 -3,-0.0 -1,-0.2 0.412 115.8 83.7-118.9 -0.3 -35.5 12.5 9.8 27 69 A T S S- 0 0 28 -5,-0.1 -3,-2.3 3,-0.0 2,-0.1 -0.911 70.0-135.8-106.7 130.3 -33.7 10.3 7.3 28 70 A A - 0 0 84 -2,-0.5 -2,-0.1 -5,-0.2 -3,-0.1 -0.447 39.3 -84.6 -73.3 156.0 -35.5 7.5 5.4 29 71 A A - 0 0 36 -2,-0.1 2,-0.5 -6,-0.1 -1,-0.1 -0.340 38.8-139.6 -53.8 137.8 -33.8 4.1 5.1 30 72 A I E +B 21 0A 13 -9,-2.3 -9,-2.2 -3,-0.1 2,-0.4 -0.935 31.4 172.4-101.4 127.2 -31.4 4.0 2.1 31 73 A E E +B 20 0A 120 -2,-0.5 2,-0.3 -11,-0.2 -11,-0.2 -0.984 20.4 163.8-145.4 129.6 -31.8 0.6 0.4 32 74 A Y E S-B 19 0A 31 -13,-2.4 -13,-2.6 -2,-0.4 4,-0.1 -0.915 89.6 -25.6-142.8 115.5 -30.4 -0.9 -2.8 33 75 A R S > S+ 0 0 95 -2,-0.3 3,-1.9 -15,-0.2 125,-0.1 0.799 92.2 154.2 50.1 29.1 -30.6 -4.7 -3.2 34 76 A A T 3 + 0 0 5 1,-0.3 124,-2.7 -15,-0.2 125,-0.4 0.670 64.5 46.6 -69.4 -18.4 -30.5 -4.5 0.6 35 77 A D T 3 S+ 0 0 107 122,-0.2 -1,-0.3 123,-0.1 2,-0.2 0.342 88.5 105.0-105.3 6.0 -32.3 -7.7 1.1 36 78 A E S < S- 0 0 66 -3,-1.9 2,-0.3 -4,-0.1 122,-0.2 -0.602 78.2-107.7 -80.4 148.4 -30.2 -9.8 -1.3 37 79 A R + 0 0 66 -2,-0.2 2,-0.3 119,-0.2 119,-0.2 -0.593 38.6 176.9 -80.0 135.8 -27.7 -12.1 0.2 38 80 A F E -E 155 0B 3 117,-2.8 117,-2.6 -2,-0.3 200,-0.0 -0.978 39.8 -94.6-129.9 146.0 -24.0 -11.3 -0.1 39 81 A A E -E 154 0B 9 -2,-0.3 115,-0.3 115,-0.2 198,-0.1 -0.343 26.7-140.5 -52.9 134.6 -21.0 -13.3 1.4 40 82 A F > + 0 0 0 113,-2.3 3,-1.9 95,-0.2 -1,-0.1 0.870 33.5 173.3 -53.0 -44.9 -20.0 -11.9 4.9 41 83 A C G > S- 0 0 0 112,-0.5 3,-1.3 102,-0.4 -1,-0.1 -0.324 72.5 -22.8 42.6-140.4 -16.3 -12.4 4.1 42 84 A S G > S+ 0 0 0 169,-0.3 3,-1.9 1,-0.3 4,-0.3 0.523 119.0 91.2 -73.8 -5.7 -14.5 -10.8 7.1 43 85 A T G X S+ 0 0 0 -3,-1.9 3,-1.2 1,-0.3 -1,-0.3 0.766 74.0 71.6 -60.5 -20.8 -17.4 -8.5 8.1 44 86 A F G <> S+ 0 0 0 -3,-1.3 4,-2.0 1,-0.2 -1,-0.3 0.748 79.9 76.7 -62.4 -23.2 -18.5 -11.4 10.4 45 87 A K H <> S+ 0 0 0 -3,-1.9 4,-2.1 2,-0.2 -1,-0.2 0.729 85.8 60.6 -64.0 -25.6 -15.5 -10.6 12.7 46 88 A A H <> S+ 0 0 0 -3,-1.2 4,-2.0 -4,-0.3 -1,-0.2 0.989 112.0 35.6 -67.2 -59.7 -17.2 -7.5 14.1 47 89 A P H > S+ 0 0 1 0, 0.0 4,-2.4 0, 0.0 -2,-0.2 0.787 113.8 61.7 -63.2 -22.3 -20.2 -9.5 15.6 48 90 A L H X S+ 0 0 0 -4,-2.0 4,-2.4 2,-0.2 -2,-0.2 0.945 105.3 45.2 -61.5 -48.1 -17.8 -12.4 16.3 49 91 A V H X S+ 0 0 0 -4,-2.1 4,-2.7 1,-0.2 5,-0.2 0.914 112.6 52.4 -64.0 -40.1 -15.8 -10.1 18.7 50 92 A A H X S+ 0 0 0 -4,-2.0 4,-2.9 2,-0.2 -1,-0.2 0.910 108.4 50.8 -55.8 -47.0 -19.1 -8.9 20.2 51 93 A A H X S+ 0 0 3 -4,-2.4 4,-2.2 2,-0.2 -2,-0.2 0.931 112.8 45.6 -58.0 -46.6 -20.1 -12.5 20.8 52 94 A V H X S+ 0 0 1 -4,-2.4 4,-1.0 2,-0.2 -2,-0.2 0.898 114.2 48.1 -66.1 -42.5 -16.8 -13.3 22.5 53 95 A L H >< S+ 0 0 5 -4,-2.7 3,-0.6 1,-0.2 -2,-0.2 0.939 114.3 47.2 -60.9 -47.3 -17.0 -10.1 24.6 54 96 A H H 3< S+ 0 0 97 -4,-2.9 -2,-0.2 1,-0.2 -1,-0.2 0.876 109.2 54.1 -59.8 -41.2 -20.6 -10.8 25.6 55 97 A Q H 3< S+ 0 0 119 -4,-2.2 -1,-0.2 -5,-0.2 -2,-0.2 0.670 110.4 41.4 -73.4 -21.1 -19.9 -14.5 26.5 56 98 A N S << S- 0 0 36 -4,-1.0 5,-0.0 -3,-0.6 2,-0.0 -0.817 89.1 -89.8-129.0 160.4 -17.1 -13.9 29.0 57 99 A P > - 0 0 94 0, 0.0 3,-2.0 0, 0.0 4,-0.3 -0.374 50.3-107.9 -58.0 152.5 -16.0 -11.6 31.8 58 100 A L G > S+ 0 0 64 1,-0.3 3,-1.9 2,-0.2 4,-0.1 0.851 116.8 63.6 -53.0 -36.1 -14.0 -8.7 30.5 59 101 A T G > S+ 0 0 100 1,-0.3 3,-1.6 2,-0.2 -1,-0.3 0.493 75.5 86.6 -76.8 -1.8 -10.7 -10.1 31.9 60 102 A H G X S+ 0 0 32 -3,-2.0 3,-1.8 1,-0.2 29,-0.5 0.731 74.8 75.9 -58.4 -25.3 -11.0 -13.1 29.5 61 103 A L G < S+ 0 0 20 -3,-1.9 29,-2.6 -4,-0.3 30,-0.4 0.707 88.7 57.5 -56.5 -21.0 -9.2 -10.7 27.2 62 104 A D G < S+ 0 0 115 -3,-1.6 2,-0.4 27,-0.2 -1,-0.3 0.429 78.3 114.2 -95.5 0.8 -6.1 -11.5 29.2 63 105 A K < - 0 0 114 -3,-1.8 26,-1.7 -4,-0.1 2,-0.4 -0.592 66.2-130.7 -72.9 127.3 -6.2 -15.2 28.5 64 106 A L E -F 88 0C 96 -2,-0.4 2,-0.5 24,-0.2 24,-0.3 -0.655 18.8-161.0 -82.9 130.2 -3.2 -16.4 26.4 65 107 A I E -F 87 0C 28 22,-2.6 22,-2.8 -2,-0.4 2,-0.3 -0.941 4.8-156.9-112.2 126.7 -4.1 -18.6 23.4 66 108 A T + 0 0 105 -2,-0.5 2,-0.3 20,-0.2 17,-0.1 -0.765 19.1 162.2-102.5 149.9 -1.4 -20.7 21.8 67 109 A Y - 0 0 11 16,-0.4 2,-0.2 -2,-0.3 19,-0.1 -0.944 15.4-152.1-155.6 170.8 -1.4 -22.0 18.2 68 110 A T > - 0 0 83 -2,-0.3 3,-1.7 16,-0.0 4,-0.5 -0.596 42.4 -61.8-137.2-165.0 1.0 -23.4 15.6 69 111 A S G > S+ 0 0 104 1,-0.3 3,-1.9 2,-0.2 14,-0.0 0.907 124.3 53.7 -51.3 -50.5 1.9 -23.9 11.9 70 112 A D G 3 S+ 0 0 114 1,-0.3 -1,-0.3 3,-0.0 0, 0.0 0.512 100.5 63.1 -73.3 -1.2 -1.2 -25.9 11.0 71 113 A D G < S+ 0 0 38 -3,-1.7 2,-0.9 1,-0.1 -1,-0.3 0.550 82.5 84.5 -92.8 -13.5 -3.5 -23.1 12.5 72 114 A I < + 0 0 58 -3,-1.9 -1,-0.1 -4,-0.5 4,-0.1 -0.794 46.9 137.3 -94.8 100.7 -2.3 -20.6 9.9 73 115 A R + 0 0 123 -2,-0.9 2,-0.3 2,-0.1 -1,-0.2 0.288 60.9 29.5-129.9 4.6 -4.6 -21.3 6.9 74 116 A S S S- 0 0 21 -3,-0.1 29,-0.2 66,-0.1 2,-0.1 -0.905 106.9 -46.5-156.7 171.8 -5.6 -17.9 5.7 75 117 A I + 0 0 73 -2,-0.3 27,-3.2 27,-0.1 28,-0.3 -0.365 60.8 164.6 -52.0 119.6 -4.4 -14.2 5.4 76 118 A S > + 0 0 9 25,-0.3 4,-1.8 26,-0.2 5,-0.2 -0.582 13.8 173.0-146.6 72.6 -3.1 -13.5 9.0 77 119 A P T 4 S+ 0 0 24 0, 0.0 4,-0.2 0, 0.0 -1,-0.1 0.745 85.9 27.9 -62.8 -25.2 -0.9 -10.3 9.1 78 120 A V T >> S+ 0 0 19 2,-0.1 3,-1.3 17,-0.1 4,-0.7 0.860 115.0 55.6-100.2 -54.6 -0.7 -10.5 12.9 79 121 A A H >> S+ 0 0 0 1,-0.3 3,-0.8 2,-0.2 4,-0.6 0.818 101.7 60.4 -52.3 -35.9 -1.0 -14.1 13.9 80 122 A Q H 3< S+ 0 0 105 -4,-1.8 3,-0.5 1,-0.2 -1,-0.3 0.876 105.1 50.9 -58.8 -35.7 1.9 -15.1 11.6 81 123 A Q H <4 S+ 0 0 132 -3,-1.3 -1,-0.2 -5,-0.2 -2,-0.2 0.629 116.1 38.6 -73.2 -20.5 4.1 -12.7 13.7 82 124 A H H XX S+ 0 0 53 -3,-0.8 4,-2.5 -4,-0.7 3,-1.5 0.277 77.0 110.9-118.8 7.1 3.2 -14.1 17.1 83 125 A V T 3< S+ 0 0 38 -4,-0.6 -16,-0.4 -3,-0.5 -1,-0.1 0.822 76.9 55.9 -55.4 -33.3 3.0 -17.8 16.4 84 126 A Q T 34 S+ 0 0 192 -4,-0.2 -1,-0.3 1,-0.2 -2,-0.1 0.736 122.2 24.3 -73.4 -20.9 6.1 -18.6 18.5 85 127 A T T <4 S- 0 0 101 -3,-1.5 -2,-0.2 1,-0.2 -1,-0.2 0.603 103.1-123.3-119.3 -19.3 4.6 -16.9 21.7 86 128 A G < - 0 0 3 -4,-2.5 2,-0.3 -7,-0.1 -20,-0.2 -0.301 18.7-106.8 92.6 174.0 0.8 -17.0 21.5 87 129 A M E -F 65 0C 0 -22,-2.8 -22,-2.6 -2,-0.1 -8,-0.0 -0.997 21.9-121.6-143.0 140.1 -1.7 -14.2 21.6 88 130 A T E > -F 64 0C 33 -2,-0.3 4,-2.4 -24,-0.3 -24,-0.2 -0.316 34.0-106.9 -72.6 163.2 -4.2 -13.1 24.3 89 131 A I H > S+ 0 0 0 -26,-1.7 4,-2.7 -29,-0.5 5,-0.2 0.884 124.3 54.7 -54.3 -38.8 -8.0 -13.0 23.5 90 132 A G H > S+ 0 0 13 -29,-2.6 4,-2.3 2,-0.2 -1,-0.2 0.931 108.2 47.2 -62.1 -46.6 -7.6 -9.2 23.5 91 133 A Q H > S+ 0 0 77 -30,-0.4 4,-3.0 2,-0.2 -1,-0.2 0.873 111.9 51.1 -59.9 -43.3 -4.8 -9.4 20.9 92 134 A L H X S+ 0 0 0 -4,-2.4 4,-2.9 2,-0.2 -2,-0.2 0.903 110.3 47.8 -61.3 -47.1 -6.9 -11.7 18.8 93 135 A C H X S+ 0 0 0 -4,-2.7 4,-2.0 2,-0.2 5,-0.3 0.920 114.0 49.0 -58.3 -42.9 -10.0 -9.4 18.9 94 136 A D H X S+ 0 0 36 -4,-2.3 4,-2.6 -5,-0.2 5,-0.5 0.958 114.5 43.2 -62.7 -52.1 -7.6 -6.6 18.0 95 137 A A H X S+ 0 0 0 -4,-3.0 6,-1.9 1,-0.2 4,-1.6 0.883 111.4 55.9 -59.9 -42.4 -6.0 -8.5 15.1 96 138 A A H < S+ 0 0 0 -4,-2.9 4,-0.3 4,-0.3 -1,-0.2 0.908 120.2 28.0 -60.6 -43.3 -9.4 -9.8 13.8 97 139 A I H < S+ 0 0 0 -4,-2.0 112,-0.3 -5,-0.2 93,-0.2 0.963 126.7 39.4 -82.4 -55.7 -10.9 -6.3 13.5 98 140 A R H < S+ 0 0 34 -4,-2.6 91,-2.1 -5,-0.3 92,-0.3 0.743 134.7 19.7 -75.6 -29.1 -8.0 -3.9 12.8 99 141 A Y S < S- 0 0 84 -4,-1.6 -1,-0.2 -5,-0.5 -3,-0.2 0.388 96.7-124.9-116.5 0.0 -6.0 -6.2 10.5 100 142 A S - 0 0 0 -5,-0.4 2,-0.3 -4,-0.3 -4,-0.3 0.903 39.6-170.0 52.0 46.8 -8.8 -8.6 9.4 101 143 A D > - 0 0 0 -6,-1.9 4,-1.4 -9,-0.2 -25,-0.3 -0.535 16.3-159.4 -72.0 124.2 -6.6 -11.5 10.6 102 144 A G H > S+ 0 0 0 -27,-3.2 4,-2.1 -2,-0.3 38,-0.3 0.866 89.8 50.9 -74.6 -39.8 -8.1 -14.8 9.5 103 145 A T H > S+ 0 0 1 -28,-0.3 4,-2.7 -29,-0.2 5,-0.2 0.906 108.2 53.7 -61.8 -42.9 -6.3 -17.0 12.1 104 146 A A H > S+ 0 0 0 1,-0.2 4,-1.9 2,-0.2 -2,-0.2 0.908 108.6 50.4 -60.2 -40.0 -7.4 -14.7 14.9 105 147 A A H X S+ 0 0 0 -4,-1.4 4,-2.5 2,-0.2 -1,-0.2 0.916 110.4 48.7 -63.3 -43.7 -11.0 -15.1 13.6 106 148 A N H X S+ 0 0 10 -4,-2.1 4,-2.3 1,-0.2 -2,-0.2 0.918 112.4 48.0 -62.8 -43.0 -10.7 -19.0 13.6 107 149 A L H X S+ 0 0 24 -4,-2.7 4,-1.4 1,-0.2 -1,-0.2 0.835 111.5 50.7 -66.9 -31.0 -9.2 -18.9 17.1 108 150 A L H X S+ 0 0 0 -4,-1.9 4,-2.2 -5,-0.2 -2,-0.2 0.891 108.7 51.2 -75.3 -37.4 -12.0 -16.6 18.3 109 151 A L H X S+ 0 0 0 -4,-2.5 4,-2.4 1,-0.2 -2,-0.2 0.934 110.1 50.0 -59.2 -45.9 -14.6 -19.0 16.8 110 152 A A H < S+ 0 0 63 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.824 107.9 54.3 -62.0 -34.3 -13.0 -21.9 18.6 111 153 A D H < S+ 0 0 44 -4,-1.4 -1,-0.2 1,-0.2 -2,-0.2 0.927 107.4 49.0 -64.7 -46.7 -13.1 -19.8 21.8 112 154 A L H < S+ 0 0 29 -4,-2.2 -2,-0.2 5,-0.1 -1,-0.2 0.891 102.5 178.9 -59.6 -42.9 -16.8 -19.3 21.4 113 155 A G < + 0 0 19 -4,-2.4 8,-0.5 4,-0.3 9,-0.2 -0.061 26.5 102.4 82.4-169.0 -17.0 -23.1 20.9 114 156 A G S > S- 0 0 58 -4,-0.2 4,-0.7 3,-0.1 3,-0.5 -0.214 77.6 -6.3 77.3-172.3 -19.8 -25.6 20.2 115 157 A P T >4>S+ 0 0 95 0, 0.0 5,-1.5 0, 0.0 3,-1.3 0.017 122.6 25.8 -56.3 155.5 -20.7 -27.2 16.8 116 158 A G G >45S- 0 0 52 1,-0.3 3,-1.1 2,-0.2 -3,-0.0 0.752 130.1 -68.7 65.4 27.7 -19.1 -26.2 13.5 117 159 A G G 345S- 0 0 38 -3,-0.5 -4,-0.3 1,-0.2 -1,-0.3 0.735 105.7 -42.0 61.2 22.7 -15.9 -25.0 15.2 118 160 A G G 5S+ 0 0 8 -3,-1.1 4,-2.2 2,-0.2 17,-0.4 0.839 76.7 51.9 -72.4 -35.8 -20.0 -21.2 13.6 120 162 A A H > S+ 0 0 36 -6,-0.5 4,-2.0 -8,-0.5 -2,-0.2 0.859 111.1 52.9 -64.9 -38.9 -22.8 -20.4 18.2 122 164 A F H X S+ 0 0 0 -4,-2.0 4,-1.7 2,-0.2 -2,-0.2 0.945 111.3 45.1 -59.8 -48.2 -21.9 -17.4 16.1 123 165 A T H X S+ 0 0 21 -4,-2.2 4,-2.4 1,-0.2 -2,-0.2 0.875 110.4 55.6 -62.3 -38.9 -25.1 -17.7 14.1 124 166 A G H X S+ 0 0 36 -4,-2.2 4,-1.8 1,-0.2 -1,-0.2 0.853 103.2 55.8 -62.1 -37.2 -27.0 -18.2 17.4 125 167 A Y H X S+ 0 0 20 -4,-2.0 4,-0.7 2,-0.2 -1,-0.2 0.914 108.4 46.2 -59.7 -45.8 -25.5 -14.9 18.6 126 168 A L H ><>S+ 0 0 0 -4,-1.7 5,-2.2 1,-0.2 3,-1.0 0.908 108.9 56.2 -63.2 -40.7 -27.0 -13.1 15.5 127 169 A R H ><5S+ 0 0 101 -4,-2.4 3,-1.9 1,-0.3 -1,-0.2 0.891 101.7 57.0 -58.0 -37.8 -30.3 -14.9 16.1 128 170 A S H 3<5S+ 0 0 87 -4,-1.8 -1,-0.3 1,-0.3 -2,-0.2 0.750 103.6 54.5 -66.3 -20.8 -30.4 -13.4 19.6 129 171 A L T <<5S- 0 0 20 -3,-1.0 -1,-0.3 -4,-0.7 -2,-0.2 0.287 127.4-100.1 -96.0 8.7 -30.1 -10.0 18.0 130 172 A G T < 5S+ 0 0 59 -3,-1.9 2,-1.0 1,-0.2 -3,-0.2 0.560 77.9 140.0 88.6 8.1 -33.2 -10.7 15.9 131 173 A D < + 0 0 8 -5,-2.2 -1,-0.2 1,-0.1 -2,-0.1 -0.765 15.3 164.8 -86.5 102.8 -31.2 -11.5 12.7 132 174 A T + 0 0 115 -2,-1.0 -1,-0.1 -3,-0.1 -5,-0.1 0.253 68.8 58.1 -98.7 10.0 -33.1 -14.5 11.2 133 175 A V S S+ 0 0 47 -7,-0.1 21,-0.1 23,-0.1 -1,-0.1 0.842 82.6 79.6-107.0 -52.8 -31.3 -14.1 7.8 134 176 A S - 0 0 0 22,-0.1 2,-0.3 19,-0.1 21,-0.2 -0.172 51.8-177.8 -66.6 154.2 -27.5 -14.3 8.2 135 177 A R - 0 0 80 19,-2.5 2,-0.5 16,-0.2 19,-0.4 -0.972 18.5-158.7-152.4 137.7 -25.6 -17.6 8.6 136 178 A L + 0 0 4 -17,-0.4 -13,-0.2 -2,-0.3 3,-0.1 -0.978 21.1 161.6-113.7 133.1 -22.0 -18.7 9.1 137 179 A D + 0 0 42 -2,-0.5 2,-0.3 1,-0.2 -1,-0.1 0.523 58.4 31.3-126.1 -19.7 -21.3 -22.3 8.1 138 180 A A - 0 0 14 -19,-0.1 -1,-0.2 5,-0.1 2,-0.1 -0.886 66.5-127.1-140.7 164.4 -17.5 -22.4 7.7 139 181 A E > - 0 0 51 -2,-0.3 4,-2.0 1,-0.1 3,-0.2 -0.414 57.9 -22.9-101.6-174.9 -14.3 -21.0 9.1 140 182 A E T 4 S+ 0 0 0 -38,-0.3 -1,-0.1 1,-0.3 -66,-0.1 -0.519 122.8 8.6 -72.0 141.7 -11.4 -19.3 7.3 141 183 A P T >4 S+ 0 0 18 0, 0.0 3,-1.6 0, 0.0 -1,-0.3 -0.995 125.2 56.4 -89.6 -4.5 -10.5 -19.6 4.5 142 184 A E G >4 S+ 0 0 98 1,-0.3 3,-1.6 -3,-0.2 4,-0.4 0.771 92.6 71.6 -61.3 -28.1 -13.6 -21.6 3.3 143 185 A L G 3< S+ 0 0 0 -4,-2.0 -102,-0.4 1,-0.3 -1,-0.3 0.709 97.8 49.8 -62.0 -20.5 -16.2 -19.0 4.4 144 186 A N G < S+ 0 0 9 -3,-1.6 69,-1.0 -5,-0.2 -1,-0.3 0.436 101.5 66.9 -92.5 -2.8 -15.1 -16.6 1.5 145 187 A R < + 0 0 111 -3,-1.6 -2,-0.2 -4,-0.2 -1,-0.1 0.398 58.8 125.0-108.2 -2.7 -15.3 -19.3 -1.2 146 188 A D - 0 0 20 -4,-0.4 3,-0.1 -3,-0.2 -107,-0.1 -0.330 68.8-104.9 -57.2 138.3 -19.0 -20.2 -1.6 147 189 A P > - 0 0 64 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 -0.246 49.0 -75.5 -65.0 159.1 -20.1 -19.8 -5.2 148 190 A P T 3 S+ 0 0 64 0, 0.0 3,-0.1 0, 0.0 -110,-0.1 -0.283 121.6 19.4 -54.6 135.4 -22.3 -16.8 -6.2 149 191 A G T 3 S+ 0 0 74 1,-0.3 2,-0.2 -112,-0.2 -112,-0.1 0.060 89.8 128.7 89.3 -25.0 -25.9 -17.3 -5.1 150 192 A D < - 0 0 62 -3,-1.9 -1,-0.3 1,-0.1 -4,-0.1 -0.463 53.2-148.2 -64.9 132.3 -25.0 -20.0 -2.5 151 193 A E > + 0 0 97 -2,-0.2 3,-1.2 -3,-0.1 -16,-0.2 0.583 60.9 113.1 -83.8 -12.1 -26.5 -19.0 0.9 152 194 A R T 3 S+ 0 0 101 1,-0.3 -16,-0.1 -15,-0.1 -6,-0.1 -0.349 87.6 6.6 -58.4 140.9 -23.8 -20.5 3.0 153 195 A D T 3 S+ 0 0 0 1,-0.2 -113,-2.3 -114,-0.1 -112,-0.5 0.792 103.7 134.8 55.6 36.9 -21.7 -17.8 4.9 154 196 A T E < +E 39 0B 6 -3,-1.2 -19,-2.5 -19,-0.4 -115,-0.2 -0.760 30.1 170.7-116.3 160.4 -24.0 -14.9 3.8 155 197 A T E -E 38 0B 0 -117,-2.6 -117,-2.8 -2,-0.3 3,-0.1 -0.736 29.6-120.1-138.7-173.0 -25.8 -11.9 5.3 156 198 A T > - 0 0 5 -2,-0.2 4,-2.4 -119,-0.2 5,-0.4 -0.955 24.8-113.2-129.9 156.2 -27.6 -9.0 3.6 157 199 A P H > S+ 0 0 0 0, 0.0 4,-1.8 0, 0.0 -137,-0.2 0.915 119.9 49.7 -52.5 -38.7 -26.9 -5.3 3.8 158 200 A H H > S+ 0 0 48 -124,-2.7 4,-1.8 2,-0.2 5,-0.2 0.946 112.1 45.2 -63.8 -50.9 -30.2 -4.9 5.7 159 201 A A H > S+ 0 0 11 -125,-0.4 4,-2.0 1,-0.2 -1,-0.2 0.914 115.5 45.1 -63.1 -46.4 -29.5 -7.7 8.3 160 202 A I H X S+ 0 0 0 -4,-2.4 4,-2.8 1,-0.2 -1,-0.2 0.847 109.0 56.6 -72.1 -33.3 -25.9 -6.7 9.0 161 203 A A H X S+ 0 0 1 -4,-1.8 4,-2.5 -5,-0.4 -1,-0.2 0.922 109.4 46.1 -59.5 -44.9 -26.7 -3.0 9.3 162 204 A L H X S+ 0 0 62 -4,-1.8 4,-1.7 2,-0.2 -2,-0.2 0.862 112.6 50.5 -70.3 -35.7 -29.3 -3.8 12.0 163 205 A V H X S+ 0 0 2 -4,-2.0 4,-2.2 2,-0.2 -2,-0.2 0.960 112.4 46.0 -61.6 -51.1 -26.9 -6.1 13.8 164 206 A L H X S+ 0 0 2 -4,-2.8 4,-2.8 1,-0.2 5,-0.5 0.902 109.0 56.6 -60.4 -42.1 -24.1 -3.4 13.8 165 207 A Q H X>S+ 0 0 65 -4,-2.5 5,-2.2 1,-0.2 4,-2.0 0.907 109.2 45.7 -52.4 -47.1 -26.6 -0.7 14.9 166 208 A Q H <5S+ 0 0 69 -4,-1.7 6,-1.6 3,-0.2 7,-0.4 0.905 115.4 47.8 -66.8 -39.7 -27.5 -2.8 18.0 167 209 A L H <5S+ 0 0 0 -4,-2.2 6,-0.3 5,-0.2 -2,-0.2 0.898 127.1 21.7 -65.1 -47.1 -23.8 -3.5 18.8 168 210 A V H <5S+ 0 0 10 -4,-2.8 -3,-0.2 -5,-0.1 -2,-0.2 0.841 137.3 24.1 -95.2 -42.2 -22.4 -0.0 18.4 169 211 A L T <5S+ 0 0 60 -4,-2.0 -3,-0.2 -5,-0.5 -4,-0.1 0.813 118.7 49.3 -98.1 -35.4 -25.4 2.4 18.9 170 212 A G S - 0 0 56 0, 0.0 4,-2.8 0, 0.0 3,-0.5 -0.376 47.1 -99.2 -62.6 152.8 -22.8 -3.4 28.2 175 217 A P H > S+ 0 0 89 0, 0.0 4,-2.1 0, 0.0 5,-0.1 0.799 120.7 51.6 -46.8 -41.4 -21.0 0.0 27.9 176 218 A D H > S+ 0 0 92 2,-0.2 4,-1.4 1,-0.2 -3,-0.0 0.921 115.5 39.6 -66.6 -44.4 -17.5 -1.3 28.7 177 219 A K H > S+ 0 0 27 -3,-0.5 4,-2.1 2,-0.2 -1,-0.2 0.835 113.0 57.0 -69.8 -36.0 -17.6 -4.1 26.1 178 220 A R H X S+ 0 0 53 -4,-2.8 4,-2.3 1,-0.2 -2,-0.2 0.872 106.7 49.5 -61.2 -40.6 -19.4 -1.8 23.6 179 221 A A H X S+ 0 0 45 -4,-2.1 4,-2.9 -5,-0.3 5,-0.2 0.871 107.0 55.2 -64.7 -40.8 -16.5 0.7 23.9 180 222 A L H X S+ 0 0 44 -4,-1.4 4,-2.0 2,-0.2 -2,-0.2 0.960 113.2 41.8 -55.6 -49.8 -13.9 -2.1 23.3 181 223 A L H X S+ 0 0 0 -4,-2.1 4,-2.1 2,-0.2 -2,-0.2 0.905 115.1 49.6 -65.0 -46.1 -15.7 -3.1 20.1 182 224 A T H X S+ 0 0 17 -4,-2.3 4,-2.2 1,-0.2 -1,-0.2 0.924 111.1 49.5 -59.9 -48.2 -16.2 0.5 18.9 183 225 A D H X S+ 0 0 92 -4,-2.9 4,-1.3 2,-0.2 -1,-0.2 0.849 108.5 52.3 -60.7 -41.1 -12.6 1.5 19.6 184 226 A W H < S+ 0 0 21 -4,-2.0 3,-0.4 -5,-0.2 -1,-0.2 0.938 112.8 45.3 -59.3 -47.2 -11.2 -1.5 17.6 185 227 A M H >< S+ 0 0 1 -4,-2.1 22,-1.9 1,-0.2 3,-1.0 0.842 110.2 55.0 -63.9 -36.6 -13.4 -0.5 14.7 186 228 A A H 3< S+ 0 0 43 -4,-2.2 -1,-0.2 20,-0.3 -2,-0.2 0.771 111.3 45.7 -61.0 -30.1 -12.3 3.1 15.1 187 229 A R T 3< S+ 0 0 124 -4,-1.3 -1,-0.2 -3,-0.4 -2,-0.2 0.203 81.9 141.5-102.2 8.7 -8.7 2.0 14.9 188 230 A N < - 0 0 23 -3,-1.0 -90,-0.2 19,-0.2 -89,-0.1 -0.248 34.1-165.8 -51.7 140.3 -9.3 -0.3 11.8 189 231 A T S S+ 0 0 65 -91,-2.1 3,-0.3 -92,-0.1 -1,-0.1 0.450 76.6 63.4-105.7 -5.0 -6.3 -0.2 9.4 190 232 A T S S+ 0 0 19 -92,-0.3 3,-0.2 -93,-0.2 -1,-0.1 0.470 89.2 66.6-100.9 -1.1 -8.0 -1.9 6.4 191 233 A G > > + 0 0 2 1,-0.2 3,-1.7 16,-0.1 5,-0.7 0.278 55.2 108.7-111.7 7.6 -10.7 0.6 5.5 192 234 A A T 3 5S+ 0 0 70 -3,-0.3 -1,-0.2 1,-0.3 -2,-0.1 0.772 86.0 46.1 -59.6 -28.9 -9.2 3.8 4.3 193 235 A K T 3 5S+ 0 0 139 -3,-0.2 61,-0.4 3,-0.1 -1,-0.3 0.191 111.4 51.2-101.8 15.4 -10.3 3.2 0.7 194 236 A R T X>5S- 0 0 9 -3,-1.7 4,-0.8 59,-0.1 3,-0.6 0.319 122.3 -11.7-117.8-115.3 -13.9 2.2 1.3 195 237 A I H >>5S+ 0 0 0 1,-0.2 3,-1.7 2,-0.2 4,-0.8 0.944 132.4 59.8 -58.8 -44.8 -16.7 3.9 3.3 196 238 A R H >4 - 0 0 66 0, 0.0 3,-2.3 0, 0.0 -2,-0.1 -0.260 36.2-106.3 -62.3 154.2 -15.7 14.0 4.4 201 243 A A T 3 S+ 0 0 99 1,-0.3 4,-0.1 -4,-0.1 -2,-0.0 0.746 115.9 62.6 -48.9 -34.5 -12.8 14.2 6.9 202 244 A D T 3 S+ 0 0 107 2,-0.1 2,-0.5 0, 0.0 -1,-0.3 0.499 87.0 86.5 -80.0 -1.5 -15.0 15.9 9.6 203 245 A W S < S- 0 0 13 -3,-2.3 2,-0.3 -7,-0.1 22,-0.2 -0.852 82.7-127.7 -92.4 130.3 -17.3 12.8 9.8 204 246 A K E -C 224 0A 102 20,-1.7 20,-2.1 -2,-0.5 2,-0.4 -0.616 27.9-168.3 -75.8 135.8 -16.1 10.1 12.2 205 247 A V E +C 223 0A 17 -2,-0.3 2,-0.4 18,-0.2 18,-0.2 -0.995 14.5 175.8-129.3 129.1 -15.9 6.7 10.6 206 248 A I E +C 222 0A 0 16,-2.3 16,-1.9 -2,-0.4 2,-0.3 -0.973 23.4 160.6-121.7 146.8 -15.4 3.3 12.3 207 249 A D E -C 221 0A 9 -22,-1.9 2,-0.3 -2,-0.4 14,-0.2 -0.973 39.5-143.9-159.1 169.0 -15.5 0.1 10.2 208 250 A K E -C 220 0A 0 12,-2.1 12,-2.0 -2,-0.3 2,-0.1 -0.954 29.3-155.0-140.8 124.7 -14.9 -3.6 9.4 209 251 A T E -C 219 0A 0 -2,-0.3 2,-0.3 -112,-0.3 10,-0.2 -0.368 6.0-159.8 -94.6 169.1 -14.1 -4.6 5.8 210 252 A G E +C 218 0A 0 8,-1.9 8,-3.2 -168,-0.2 2,-0.3 -0.975 9.1 177.3-148.7 146.5 -14.5 -7.9 3.9 211 253 A T E +C 217 0A 20 -2,-0.3 -169,-0.3 6,-0.2 2,-0.3 -0.985 15.3 143.8-147.2 139.8 -12.8 -9.2 0.8 212 254 A G E > -C 216 0A 13 4,-2.1 4,-0.9 -2,-0.3 3,-0.4 -0.908 46.2 -52.7-160.3-169.0 -13.1 -12.5 -1.0 213 255 A D T >4 S+ 0 0 45 -69,-1.0 3,-0.7 -2,-0.3 32,-0.2 -0.156 106.9 46.3 -76.1 170.1 -13.3 -14.5 -4.2 214 256 A Y T 34 S- 0 0 41 30,-2.3 25,-2.8 1,-0.2 -1,-0.2 0.771 136.1 -66.7 62.1 26.7 -15.6 -13.6 -7.1 215 257 A G T 34 S+ 0 0 0 31,-1.1 34,-0.5 29,-0.4 2,-0.4 0.803 81.6 176.0 66.9 34.7 -14.5 -10.0 -6.6 216 258 A R E << +C 212 0A 16 -4,-0.9 -4,-2.1 -3,-0.7 2,-0.3 -0.572 9.2 165.1 -78.8 128.0 -16.1 -9.6 -3.2 217 259 A A E +CD 211 237A 0 20,-1.6 20,-0.6 -2,-0.4 2,-0.3 -0.943 7.1 170.6-143.3 117.2 -15.6 -6.4 -1.4 218 260 A N E -CD 210 236A 1 -8,-3.2 -8,-1.9 -2,-0.3 2,-0.3 -0.841 12.0-175.8-119.6 159.2 -17.7 -5.3 1.7 219 261 A D E -CD 209 235A 0 16,-3.0 16,-3.0 -2,-0.3 2,-0.4 -0.905 2.9-171.8-151.9 132.9 -17.5 -2.6 4.3 220 262 A I E +CD 208 234A 2 -12,-2.0 -12,-2.1 -2,-0.3 2,-0.3 -0.994 22.8 164.5-122.3 133.5 -19.8 -2.1 7.3 221 263 A A E -CD 207 233A 0 12,-2.8 12,-2.4 -2,-0.4 2,-0.4 -0.920 38.3-139.2-142.0 159.3 -19.4 1.1 9.3 222 264 A V E -CD 206 232A 0 -16,-1.9 -16,-2.3 -2,-0.3 2,-0.3 -0.992 30.9-172.7-114.7 134.9 -20.8 3.5 11.8 223 265 A V E -CD 205 231A 0 8,-2.7 8,-2.5 -2,-0.4 2,-0.4 -0.929 12.2-153.8-126.9 150.9 -20.4 7.1 10.9 224 266 A W E -CD 204 230A 48 -20,-2.1 -20,-1.7 -2,-0.3 -2,-0.0 -0.993 18.1-128.4-127.5 126.8 -21.0 10.3 12.8 225 267 A S > - 0 0 14 4,-2.7 3,-2.5 -2,-0.4 -21,-0.2 -0.111 42.0 -93.2 -60.5 166.1 -21.8 13.7 11.3 226 268 A P T 3 S+ 0 0 73 0, 0.0 -1,-0.1 0, 0.0 -23,-0.1 0.655 130.5 54.0 -58.3 -10.3 -19.7 16.7 12.4 227 269 A T T 3 S- 0 0 124 2,-0.1 -2,-0.1 0, 0.0 -24,-0.1 0.216 124.2-101.5-107.3 14.8 -22.6 17.3 14.9 228 270 A G S < S+ 0 0 46 -3,-2.5 -25,-0.0 1,-0.3 -5,-0.0 0.714 71.2 146.2 78.9 19.8 -22.5 13.8 16.4 229 271 A V - 0 0 57 2,-0.0 -4,-2.7 1,-0.0 -1,-0.3 -0.816 39.4-143.0 -89.4 119.1 -25.5 12.3 14.6 230 272 A P E + D 0 224A 45 0, 0.0 2,-0.3 0, 0.0 -6,-0.2 -0.578 21.5 179.0 -90.0 151.0 -24.8 8.6 13.9 231 273 A Y E - D 0 223A 22 -8,-2.5 -8,-2.7 -2,-0.2 2,-0.4 -0.992 22.5-135.2-141.6 145.0 -25.7 6.5 10.8 232 274 A V E - D 0 222A 2 -2,-0.3 2,-0.4 -210,-0.2 -10,-0.2 -0.877 21.7-168.1-104.7 135.7 -25.0 2.8 10.0 233 275 A V E - D 0 221A 0 -12,-2.4 -12,-2.8 -2,-0.4 2,-0.5 -0.985 8.2-176.9-131.0 117.8 -23.7 2.1 6.5 234 276 A A E +AD 20 220A 0 -214,-2.3 -214,-2.0 -2,-0.4 2,-0.4 -0.978 6.3 176.2-115.7 118.4 -23.5 -1.4 5.0 235 277 A V E +AD 19 219A 0 -16,-3.0 -16,-3.0 -2,-0.5 2,-0.3 -0.997 3.5 172.6-125.0 127.2 -22.0 -1.7 1.5 236 278 A M E +AD 18 218A 0 -218,-2.4 -218,-3.4 -2,-0.4 2,-0.3 -0.973 2.9 167.2-133.9 146.0 -21.5 -5.1 -0.1 237 279 A S E -AD 17 217A 1 -20,-0.6 -20,-1.6 -2,-0.3 2,-0.3 -0.990 13.9-175.5-155.3 155.6 -20.4 -6.1 -3.6 238 280 A D E -A 16 0A 12 -222,-1.6 -222,-2.6 -2,-0.3 -23,-0.2 -0.954 20.7-150.6-145.9 162.5 -19.2 -8.9 -5.9 239 281 A R > + 0 0 39 -25,-2.8 3,-2.9 -2,-0.3 4,-0.2 -0.442 34.3 157.1-126.9 51.5 -18.1 -9.1 -9.5 240 282 A A G > + 0 0 29 1,-0.3 3,-2.1 2,-0.2 -1,-0.1 0.729 62.5 75.9 -54.8 -27.7 -19.2 -12.8 -10.0 241 283 A G G 3 S+ 0 0 66 -227,-0.4 -1,-0.3 1,-0.3 3,-0.1 0.656 92.3 55.1 -56.9 -19.6 -19.3 -12.1 -13.8 242 284 A G G < S- 0 0 38 -3,-2.9 3,-0.4 1,-0.3 -1,-0.3 0.357 109.7-127.5 -93.9 2.8 -15.5 -12.3 -13.7 243 285 A G X - 0 0 28 -3,-2.1 3,-1.6 1,-0.2 -1,-0.3 -0.280 51.9 -37.3 80.2-171.9 -15.5 -15.8 -12.1 244 286 A Y T 3 S+ 0 0 99 1,-0.3 -30,-2.3 -30,-0.1 -29,-0.4 0.794 138.1 49.8 -56.1 -38.0 -13.6 -16.9 -9.0 245 287 A D T 3 S+ 0 0 133 -3,-0.4 -1,-0.3 -32,-0.2 -2,-0.1 0.253 76.2 137.0 -91.8 9.9 -10.5 -14.8 -9.8 246 288 A A < - 0 0 12 -3,-1.6 -31,-1.1 1,-0.1 -30,-0.2 -0.338 61.6-111.0 -54.8 136.0 -12.4 -11.5 -10.4 247 289 A E - 0 0 137 -33,-0.1 2,-0.1 -32,-0.1 -1,-0.1 -0.552 24.4-122.3 -73.0 130.0 -10.6 -8.6 -8.7 248 290 A P - 0 0 37 0, 0.0 2,-0.5 0, 0.0 -32,-0.2 -0.493 25.9-147.3 -64.7 144.8 -12.3 -7.0 -5.7 249 291 A R >> - 0 0 97 -34,-0.5 3,-1.4 1,-0.1 4,-0.7 -0.817 21.7-179.3-128.1 95.3 -12.8 -3.3 -6.4 250 292 A E H 3> S+ 0 0 56 -2,-0.5 4,-2.3 1,-0.3 3,-0.5 0.791 80.6 69.9 -57.6 -36.2 -12.6 -1.0 -3.4 251 293 A A H 3> S+ 0 0 45 1,-0.2 4,-2.7 2,-0.2 -1,-0.3 0.828 92.0 59.5 -53.7 -35.5 -13.3 2.0 -5.6 252 294 A L H <> S+ 0 0 0 -3,-1.4 4,-2.4 2,-0.2 -1,-0.2 0.916 107.7 44.6 -58.7 -45.5 -16.9 0.8 -6.1 253 295 A L H X S+ 0 0 0 -4,-0.7 4,-2.9 -3,-0.5 -2,-0.2 0.884 111.9 52.5 -67.6 -40.7 -17.5 1.0 -2.3 254 296 A A H X S+ 0 0 17 -4,-2.3 4,-2.0 -61,-0.4 -2,-0.2 0.930 112.5 45.5 -58.1 -46.2 -15.8 4.4 -2.1 255 297 A E H X S+ 0 0 62 -4,-2.7 4,-2.0 2,-0.2 -2,-0.2 0.911 113.7 48.1 -66.1 -43.9 -18.1 5.7 -4.9 256 298 A A H X S+ 0 0 0 -4,-2.4 4,-2.4 1,-0.2 -2,-0.2 0.943 111.5 50.7 -62.0 -46.3 -21.2 4.2 -3.3 257 299 A A H X S+ 0 0 0 -4,-2.9 4,-3.0 1,-0.2 -1,-0.2 0.879 106.9 54.8 -58.4 -37.6 -20.3 5.6 0.0 258 300 A T H X S+ 0 0 77 -4,-2.0 4,-2.3 2,-0.2 -1,-0.2 0.921 107.9 50.0 -61.7 -42.1 -19.8 9.1 -1.6 259 301 A C H X S+ 0 0 32 -4,-2.0 4,-1.4 1,-0.2 -2,-0.2 0.920 112.6 46.6 -60.8 -46.5 -23.4 8.8 -3.0 260 302 A V H X S+ 0 0 0 -4,-2.4 4,-2.1 2,-0.2 3,-0.3 0.917 111.0 50.9 -60.1 -46.9 -24.6 7.9 0.5 261 303 A A H X S+ 0 0 6 -4,-3.0 4,-1.6 1,-0.2 -2,-0.2 0.857 104.6 59.4 -62.3 -38.1 -22.7 10.8 2.2 262 304 A G H < S+ 0 0 58 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.905 109.5 42.8 -52.1 -46.3 -24.2 13.1 -0.4 263 305 A V H < S+ 0 0 85 -4,-1.4 -2,-0.2 -3,-0.3 -1,-0.2 0.889 115.3 48.5 -70.6 -40.2 -27.7 12.2 0.8 264 306 A L H < 0 0 14 -4,-2.1 -1,-0.2 -237,-0.0 -2,-0.2 0.605 360.0 360.0 -78.7 -16.4 -26.8 12.3 4.5 265 307 A A < 0 0 102 -4,-1.6 -3,-0.0 -5,-0.2 -40,-0.0 -0.145 360.0 360.0 -81.6 360.0 -25.1 15.7 4.5 266 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 267 308 A X 0 0 156 0, 0.0 -191,-0.1 0, 0.0 -168,-0.0 0.000 360.0 360.0 360.0 360.0 -3.8 -7.2 3.4