==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 09-AUG-13 4M6G . COMPND 2 MOLECULE: PEPTIDOGLYCAN AMIDASE RV3717; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR D.M.PRIGOZHIN,D.MAVRICI,J.P.HUIZAR,H.J.VANSELL,T.ALBER,TB ST . 216 2 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8648.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 139 64.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 26 12.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 12 5.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 10 4.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 18 8.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 63 29.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 1 0 0 1 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 24 A I > 0 0 69 0, 0.0 3,-1.6 0, 0.0 2,-0.1 0.000 360.0 360.0 360.0 1.5 0.9 9.9 -0.4 2 25 A A T 3 + 0 0 76 1,-0.2 65,-0.2 65,-0.1 64,-0.1 -0.397 360.0 24.7 -63.5 135.9 4.0 8.1 -1.4 3 26 A G T 3 S+ 0 0 29 63,-1.9 -1,-0.2 1,-0.3 64,-0.1 0.256 90.2 132.5 93.2 -12.2 3.3 4.6 -2.7 4 27 A M < - 0 0 33 -3,-1.6 64,-2.6 1,-0.1 2,-0.5 -0.293 56.7-117.8 -69.9 159.5 -0.2 5.4 -3.7 5 28 A V E +a 68 0A 28 62,-0.2 91,-2.1 89,-0.2 92,-1.5 -0.886 29.6 179.9-109.8 121.5 -1.5 4.4 -7.2 6 29 A V E -ab 69 97A 0 62,-2.7 64,-1.4 -2,-0.5 2,-0.5 -0.977 14.9-152.8-120.6 127.2 -2.6 6.9 -9.8 7 30 A F E -ab 70 98A 5 90,-2.1 92,-2.5 -2,-0.5 2,-0.5 -0.867 13.6-160.1 -97.0 125.2 -3.8 5.9 -13.3 8 31 A I E -ab 71 99A 0 62,-3.2 64,-1.9 -2,-0.5 65,-0.3 -0.914 6.3-169.6-111.9 126.8 -3.2 8.6 -15.9 9 32 A D E - b 0 100A 19 90,-2.4 92,-2.9 -2,-0.5 2,-0.9 -0.869 10.3-160.7-121.7 98.0 -5.2 8.6 -19.2 10 33 A P E - b 0 101A 0 0, 0.0 92,-0.1 0, 0.0 42,-0.1 -0.695 39.8-116.3 -71.1 108.0 -4.1 11.0 -22.0 11 34 A G + 0 0 1 90,-2.1 40,-0.2 -2,-0.9 41,-0.2 -0.049 68.7 3.2 -50.8 145.9 -7.4 11.1 -23.9 12 35 A H S S- 0 0 0 205,-0.4 2,-0.2 69,-0.1 25,-0.1 0.106 85.2 -73.9 70.3 179.6 -7.5 9.7 -27.5 13 36 A N - 0 0 0 23,-0.4 66,-0.2 67,-0.1 35,-0.1 -0.716 22.6-126.8-110.7 160.9 -4.9 8.0 -29.7 14 37 A G S S+ 0 0 14 64,-1.3 2,-0.3 61,-0.3 65,-0.2 0.716 99.6 13.7 -75.4 -21.1 -1.8 9.2 -31.6 15 38 A A S S- 0 0 38 63,-1.3 65,-0.4 33,-0.0 2,-0.3 -0.992 71.6-161.1-152.7 152.5 -3.3 7.6 -34.7 16 39 A N + 0 0 58 -2,-0.3 2,-0.2 63,-0.1 63,-0.1 -0.901 9.6 175.9-133.7 160.4 -6.6 6.1 -35.8 17 40 A D > - 0 0 84 -2,-0.3 3,-1.5 0, 0.0 4,-0.1 -0.762 58.1 -70.4-140.6-164.6 -8.2 3.9 -38.4 18 41 A A G > S+ 0 0 96 1,-0.3 3,-1.7 -2,-0.2 4,-0.1 0.698 115.9 79.5 -65.8 -18.2 -11.6 2.5 -39.1 19 42 A S G > S+ 0 0 58 1,-0.3 3,-1.4 2,-0.2 -1,-0.3 0.618 74.0 74.9 -68.3 -13.0 -11.4 0.2 -36.0 20 43 A I G < S+ 0 0 28 -3,-1.5 15,-2.0 1,-0.3 14,-0.4 0.622 85.5 65.0 -76.0 -10.3 -12.3 3.1 -33.7 21 44 A G G < S+ 0 0 35 -3,-1.7 -1,-0.3 12,-0.2 -2,-0.2 0.426 75.6 121.6 -87.3 -1.4 -15.9 2.8 -34.9 22 45 A R S < S- 0 0 179 -3,-1.4 12,-2.0 1,-0.1 2,-0.4 -0.397 71.5-112.3 -60.5 136.1 -16.0 -0.6 -33.2 23 46 A Q E +G 33 0B 95 10,-0.2 10,-0.2 -2,-0.1 -1,-0.1 -0.609 40.2 174.7 -82.8 128.7 -18.7 -0.7 -30.6 24 47 A V E -G 32 0B 10 8,-2.6 8,-2.2 -2,-0.4 140,-0.0 -0.894 39.0 -84.0-127.9 157.2 -17.7 -1.0 -27.0 25 48 A P E -G 31 0B 68 0, 0.0 6,-0.2 0, 0.0 143,-0.1 -0.257 22.2-153.0 -64.0 148.5 -19.8 -1.0 -23.8 26 49 A T - 0 0 22 4,-2.0 141,-0.2 141,-0.1 142,-0.2 0.654 39.8-118.2 -88.6 -20.1 -20.8 2.4 -22.3 27 50 A G S S+ 0 0 28 3,-0.5 4,-0.1 140,-0.1 136,-0.0 0.390 104.4 75.1 91.2 -1.5 -21.1 0.9 -18.8 28 51 A R S S- 0 0 73 2,-0.2 3,-0.1 134,-0.1 136,-0.0 0.007 121.4 -82.2-130.8 27.7 -24.8 1.8 -18.8 29 52 A G S S+ 0 0 86 1,-0.3 2,-0.1 0, 0.0 0, 0.0 0.237 102.2 79.7 100.2 -13.5 -26.2 -0.8 -21.1 30 53 A G S S- 0 0 37 -6,-0.0 -4,-2.0 0, 0.0 -3,-0.5 -0.370 70.5-116.3-108.9-169.4 -25.5 0.7 -24.5 31 54 A T E -G 25 0B 88 -6,-0.2 2,-0.3 -5,-0.1 -8,-0.1 -0.914 23.7-179.9-126.6 160.0 -22.6 0.9 -26.8 32 55 A K E -G 24 0B 49 -8,-2.2 -8,-2.6 -2,-0.3 2,-0.0 -0.915 44.6 -63.3-145.3 173.0 -20.5 3.7 -28.2 33 56 A N E -G 23 0B 85 -2,-0.3 50,-0.2 -10,-0.2 -12,-0.2 -0.311 41.7-124.8 -62.5 140.6 -17.5 4.1 -30.5 34 57 A a S S- 0 0 5 -12,-2.0 49,-2.2 -14,-0.4 2,-0.3 0.887 86.4 -13.2 -51.0 -45.7 -14.2 2.5 -29.4 35 58 A Q - 0 0 5 -15,-2.0 2,-0.3 47,-0.2 -1,-0.1 -0.895 57.9-138.4-146.4 177.6 -12.5 5.8 -29.8 36 59 A A - 0 0 34 -2,-0.3 -23,-0.4 181,-0.1 -15,-0.0 -0.982 22.8-127.9-140.1 148.6 -12.7 9.3 -31.2 37 60 A S - 0 0 73 -2,-0.3 11,-0.4 1,-0.1 10,-0.1 0.762 47.8-142.5 -70.1 -25.1 -10.0 11.3 -33.0 38 61 A G - 0 0 27 178,-0.3 -1,-0.1 9,-0.1 66,-0.1 -0.098 16.9 -76.7 84.4 172.7 -10.5 14.4 -30.7 39 62 A T - 0 0 34 64,-0.4 8,-3.3 7,-0.1 9,-0.4 -0.135 37.4-155.6 -97.3-167.9 -10.4 18.1 -31.5 40 63 A S B -H 46 0C 36 6,-0.3 147,-0.0 7,-0.1 -2,-0.0 -0.981 24.8 -89.5-163.2 164.0 -7.6 20.6 -32.2 41 64 A T > - 0 0 3 4,-2.4 3,-1.6 -2,-0.3 141,-0.2 -0.221 49.1 -99.0 -71.6 170.1 -6.6 24.3 -32.1 42 65 A N T 3 S+ 0 0 131 139,-0.6 -1,-0.1 1,-0.3 140,-0.1 0.753 124.8 54.4 -62.3 -24.3 -7.2 26.5 -35.1 43 66 A S T 3 S- 0 0 88 2,-0.1 -1,-0.3 0, 0.0 -2,-0.0 0.402 125.8 -98.1 -93.6 1.4 -3.5 26.1 -36.0 44 67 A G < + 0 0 47 -3,-1.6 -2,-0.1 1,-0.3 0, 0.0 0.574 69.6 149.6 97.5 10.5 -3.7 22.3 -36.1 45 68 A Y - 0 0 35 136,-0.1 -4,-2.4 1,-0.0 -1,-0.3 -0.706 44.5-132.8 -77.9 112.3 -2.4 21.5 -32.6 46 69 A P B > -H 40 0C 35 0, 0.0 4,-1.9 0, 0.0 3,-0.4 -0.299 9.3-131.5 -75.5 147.1 -4.2 18.2 -31.8 47 70 A E H > S+ 0 0 0 -8,-3.3 4,-2.8 1,-0.2 5,-0.3 0.885 108.1 58.6 -55.8 -42.7 -6.1 17.3 -28.5 48 71 A H H > S+ 0 0 37 -9,-0.4 4,-1.3 -11,-0.4 -1,-0.2 0.807 107.8 44.0 -64.8 -31.1 -4.3 13.9 -28.5 49 72 A T H > S+ 0 0 24 -3,-0.4 4,-3.0 2,-0.2 5,-0.3 0.871 112.5 53.4 -77.2 -38.9 -0.8 15.5 -28.5 50 73 A F H X S+ 0 0 0 -4,-1.9 4,-2.3 1,-0.2 5,-0.2 0.930 112.7 42.5 -59.8 -47.9 -1.9 18.0 -25.9 51 74 A T H X S+ 0 0 0 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.864 115.4 50.5 -69.3 -36.6 -3.2 15.3 -23.5 52 75 A W H X S+ 0 0 43 -4,-1.3 4,-1.9 -5,-0.3 -2,-0.2 0.961 114.4 42.8 -62.9 -52.5 -0.1 13.2 -24.2 53 76 A E H X S+ 0 0 60 -4,-3.0 4,-1.2 1,-0.2 -2,-0.2 0.852 117.7 45.6 -64.6 -37.4 2.4 16.0 -23.5 54 77 A T H X S+ 0 0 0 -4,-2.3 4,-2.3 -5,-0.3 -1,-0.2 0.880 110.4 54.2 -73.8 -38.2 0.5 17.2 -20.5 55 78 A G H X S+ 0 0 0 -4,-2.3 4,-2.9 -5,-0.2 -2,-0.2 0.855 103.8 55.9 -62.7 -36.7 0.1 13.7 -19.1 56 79 A L H X S+ 0 0 53 -4,-1.9 4,-2.2 2,-0.2 -1,-0.2 0.900 109.3 46.2 -62.2 -41.6 3.8 13.1 -19.3 57 80 A R H X S+ 0 0 113 -4,-1.2 4,-2.0 2,-0.2 -2,-0.2 0.889 113.2 49.3 -67.6 -40.8 4.5 16.2 -17.2 58 81 A L H X S+ 0 0 0 -4,-2.3 4,-2.2 1,-0.2 5,-0.2 0.928 111.5 50.1 -61.0 -46.2 1.8 15.1 -14.7 59 82 A R H X S+ 0 0 105 -4,-2.9 4,-2.3 1,-0.2 -2,-0.2 0.892 109.6 50.7 -59.3 -44.0 3.3 11.6 -14.6 60 83 A A H X S+ 0 0 37 -4,-2.2 4,-1.8 2,-0.2 -1,-0.2 0.896 111.1 47.2 -63.5 -43.5 6.8 13.0 -14.0 61 84 A A H X S+ 0 0 28 -4,-2.0 4,-0.9 2,-0.2 -2,-0.2 0.906 113.1 47.6 -68.1 -43.3 5.7 15.2 -11.1 62 85 A L H ><>S+ 0 0 0 -4,-2.2 5,-2.1 1,-0.2 3,-0.7 0.900 109.9 54.3 -63.0 -41.6 3.7 12.4 -9.4 63 86 A N H ><5S+ 0 0 70 -4,-2.3 3,-1.5 1,-0.2 -1,-0.2 0.878 104.1 54.9 -57.7 -39.8 6.7 10.1 -9.8 64 87 A A H 3<5S+ 0 0 87 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.746 103.2 56.7 -66.6 -24.3 8.9 12.6 -8.1 65 88 A L T <<5S- 0 0 81 -4,-0.9 -1,-0.3 -3,-0.7 -2,-0.2 0.452 123.0-107.0 -85.5 -1.6 6.5 12.5 -5.1 66 89 A G T < 5S+ 0 0 41 -3,-1.5 -63,-1.9 1,-0.3 2,-0.3 0.471 72.2 146.9 88.6 3.4 7.0 8.8 -4.9 67 90 A V < - 0 0 3 -5,-2.1 -1,-0.3 -65,-0.2 2,-0.3 -0.554 50.0-123.8 -75.4 132.3 3.5 8.1 -6.3 68 91 A R E -a 5 0A 160 -64,-2.6 -62,-2.7 -2,-0.3 2,-0.3 -0.579 37.4-175.2 -73.6 136.6 3.1 5.0 -8.4 69 92 A T E -a 6 0A 36 -2,-0.3 2,-0.3 -64,-0.2 -62,-0.2 -0.957 19.7-176.4-137.2 153.5 1.8 5.8 -11.9 70 93 A A E -a 7 0A 29 -64,-1.4 -62,-3.2 -2,-0.3 2,-0.3 -0.990 19.4-135.6-144.1 147.8 0.6 4.1 -15.1 71 94 A L E -a 8 0A 35 -2,-0.3 -62,-0.2 -64,-0.2 3,-0.1 -0.772 13.8-136.2-104.0 149.1 -0.5 5.5 -18.5 72 95 A S S S+ 0 0 5 -64,-1.9 2,-0.3 -2,-0.3 -63,-0.1 0.754 95.5 14.5 -70.8 -24.1 -3.5 4.4 -20.5 73 96 A R - 0 0 14 -65,-0.3 -1,-0.2 7,-0.1 7,-0.1 -0.977 62.1-146.6-148.2 159.8 -1.2 4.5 -23.6 74 97 A G S S+ 0 0 63 -2,-0.3 2,-0.3 -3,-0.1 6,-0.0 0.202 74.0 30.1-117.2 15.1 2.6 4.7 -24.2 75 98 A N - 0 0 53 3,-0.1 -61,-0.3 4,-0.0 3,-0.0 -0.982 54.4-138.3-161.1 171.7 2.8 6.8 -27.4 76 99 A D S S+ 0 0 32 -2,-0.3 -63,-0.1 -62,-0.1 3,-0.1 -0.148 94.4 61.8-126.2 35.6 1.4 9.6 -29.6 77 100 A N S S+ 0 0 125 2,-0.1 2,-0.3 -62,-0.1 -1,-0.1 0.322 96.8 44.8-143.3 4.8 1.9 7.9 -33.0 78 101 A A S S- 0 0 38 -63,-0.1 -63,-1.3 -3,-0.0 -64,-1.3 -0.856 93.0 -65.6-142.2 177.0 -0.1 4.7 -33.0 79 102 A L - 0 0 72 -2,-0.3 -63,-0.1 -65,-0.2 -2,-0.1 -0.385 48.9-159.5 -67.4 144.7 -3.5 3.3 -32.1 80 103 A G - 0 0 18 -65,-0.4 -67,-0.1 1,-0.1 -7,-0.1 -0.639 29.9 -68.4-117.3 177.8 -4.4 3.2 -28.4 81 104 A P - 0 0 18 0, 0.0 -1,-0.1 0, 0.0 -69,-0.1 -0.294 53.2-102.4 -68.9 149.4 -6.9 1.3 -26.3 82 105 A a > - 0 0 22 1,-0.1 4,-1.7 -47,-0.1 -47,-0.2 -0.126 38.9-100.2 -63.5 168.3 -10.7 1.8 -26.6 83 106 A V H > S+ 0 0 5 -49,-2.2 4,-0.8 -50,-0.2 -1,-0.1 0.783 122.2 49.2 -70.0 -27.6 -12.5 3.8 -24.0 84 107 A D H > S+ 0 0 29 2,-0.2 4,-2.1 1,-0.2 3,-0.4 0.893 108.5 53.8 -74.9 -38.6 -13.8 0.8 -22.0 85 108 A E H > S+ 0 0 88 1,-0.2 4,-3.1 2,-0.2 5,-0.2 0.857 102.4 57.8 -63.3 -36.4 -10.4 -0.8 -22.0 86 109 A R H X S+ 0 0 9 -4,-1.7 4,-1.3 1,-0.2 -1,-0.2 0.834 109.1 46.0 -64.1 -32.0 -8.8 2.3 -20.5 87 110 A A H X S+ 0 0 5 -4,-0.8 4,-2.6 -3,-0.4 83,-0.2 0.867 112.8 49.7 -74.6 -39.0 -11.3 1.9 -17.6 88 111 A N H X S+ 0 0 80 -4,-2.1 4,-2.1 2,-0.2 -2,-0.2 0.887 107.7 53.3 -68.0 -40.5 -10.6 -1.8 -17.3 89 112 A M H X S+ 0 0 64 -4,-3.1 4,-0.6 2,-0.2 -1,-0.2 0.924 112.1 46.7 -55.6 -47.2 -6.8 -1.2 -17.2 90 113 A A H >< S+ 0 0 2 -4,-1.3 3,-1.6 -5,-0.2 4,-0.4 0.945 109.3 52.7 -61.9 -51.3 -7.4 1.3 -14.4 91 114 A N H >< S+ 0 0 15 -4,-2.6 3,-1.6 1,-0.3 -1,-0.2 0.852 102.4 59.3 -54.4 -39.2 -9.7 -1.1 -12.4 92 115 A A H 3< S+ 0 0 84 -4,-2.1 -1,-0.3 1,-0.3 -2,-0.2 0.728 105.0 51.1 -63.4 -22.2 -7.1 -3.9 -12.5 93 116 A L T << S- 0 0 79 -3,-1.6 -1,-0.3 -4,-0.6 -2,-0.2 0.474 97.0-143.4 -93.1 -3.8 -4.7 -1.5 -10.7 94 117 A R < - 0 0 182 -3,-1.6 -3,-0.2 -4,-0.4 -89,-0.2 0.873 32.7-160.7 40.4 54.1 -7.2 -0.7 -8.0 95 118 A P - 0 0 3 0, 0.0 -89,-0.2 0, 0.0 3,-0.1 -0.120 31.7-135.6 -72.2 157.9 -5.9 2.9 -8.0 96 119 A N S S+ 0 0 51 -91,-2.1 2,-0.3 1,-0.3 -90,-0.2 0.694 94.9 8.9 -78.1 -20.9 -6.3 5.5 -5.2 97 120 A A E -b 6 0A 0 -92,-1.5 -90,-2.1 74,-0.1 2,-0.4 -0.955 61.8-160.9-159.9 140.7 -7.1 7.9 -8.0 98 121 A I E -bc 7 173A 9 74,-2.2 76,-2.3 -2,-0.3 2,-0.4 -0.990 12.5-176.0-124.1 128.8 -7.8 7.9 -11.7 99 122 A V E -bc 8 174A 0 -92,-2.5 -90,-2.4 -2,-0.4 2,-0.4 -0.985 7.0-165.3-129.9 127.2 -7.5 11.0 -13.9 100 123 A S E -bc 9 175A 8 74,-2.3 76,-2.9 -2,-0.4 2,-0.4 -0.913 12.9-146.1-110.3 137.0 -8.4 11.4 -17.6 101 124 A L E +bc 10 176A 0 -92,-2.9 -90,-2.1 -2,-0.4 2,-0.3 -0.873 27.3 151.9-110.1 131.9 -7.2 14.4 -19.6 102 125 A H E - c 0 177A 3 74,-2.4 76,-2.8 -2,-0.4 2,-0.3 -0.930 29.6-143.5-143.8 166.2 -9.1 16.1 -22.5 103 126 A A E - 0 0 0 -2,-0.3 -64,-0.4 74,-0.2 77,-0.2 -0.997 26.2-124.3-136.0 140.6 -9.5 19.4 -24.2 104 127 A D E - c 0 180A 33 75,-3.0 77,-2.4 -2,-0.3 78,-0.4 -0.233 6.6-150.7 -84.8 163.9 -12.8 20.7 -25.6 105 128 A G + 0 0 38 75,-0.2 75,-0.1 76,-0.2 3,-0.1 -0.598 49.5 136.1-127.5 69.9 -13.8 22.0 -29.0 106 129 A G - 0 0 17 1,-0.2 76,-0.1 -2,-0.1 2,-0.0 -0.233 61.2 -41.9-104.6-167.7 -16.5 24.4 -28.1 107 130 A P > - 0 0 78 0, 0.0 3,-2.3 0, 0.0 -1,-0.2 -0.355 54.2-123.6 -59.7 134.6 -17.6 28.0 -29.1 108 131 A A T 3 S+ 0 0 58 1,-0.3 72,-0.1 -3,-0.1 -2,-0.1 0.752 110.1 63.4 -52.3 -27.8 -14.5 30.2 -29.5 109 132 A S T 3 S+ 0 0 122 74,-0.1 -1,-0.3 75,-0.1 2,-0.3 0.774 92.2 78.9 -68.9 -27.8 -16.1 32.6 -27.0 110 133 A G < + 0 0 7 -3,-2.3 2,-0.3 41,-0.1 -4,-0.1 -0.597 55.3 160.5 -87.3 144.6 -15.9 30.0 -24.2 111 134 A R + 0 0 89 -2,-0.3 39,-0.8 37,-0.1 40,-0.2 -0.949 24.5 62.2-149.8 169.3 -12.8 29.1 -22.3 112 135 A G S S- 0 0 0 -2,-0.3 36,-0.3 37,-0.2 2,-0.2 -0.258 70.5 -63.1 101.4 173.6 -11.7 27.4 -19.1 113 136 A F B -i 148 0D 0 34,-2.3 36,-3.5 65,-0.1 2,-0.3 -0.493 30.1-170.8 -96.7 160.5 -11.9 24.0 -17.5 114 137 A H E -D 177 0A 5 63,-2.0 63,-2.5 34,-0.2 2,-0.6 -0.962 17.8-138.7-145.4 143.0 -14.6 21.7 -16.2 115 138 A V E -De 176 157A 0 41,-2.5 43,-1.9 -2,-0.3 2,-0.3 -0.870 17.4-152.5-103.3 117.6 -14.3 18.4 -14.2 116 139 A N E +De 175 158A 0 59,-3.3 59,-2.4 -2,-0.6 2,-0.3 -0.658 17.3 173.4 -90.0 142.1 -16.5 15.5 -15.3 117 140 A Y E - 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