==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 09-AUG-13 4M6L . COMPND 2 MOLECULE: DIHYDROFOLATE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR G.BHABHA,D.C.EKIERT,P.E.WRIGHT,I.A.WILSON . 187 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10143.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 117 62.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 27 14.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 22 11.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 32 17.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A V 0 0 89 0, 0.0 110,-0.2 0, 0.0 109,-0.1 0.000 360.0 360.0 360.0 -48.1 30.5 -10.7 -10.0 2 2 A G - 0 0 37 108,-2.7 109,-0.1 1,-0.3 108,-0.0 0.088 360.0 -32.0 -89.4-152.5 29.7 -11.9 -13.5 3 3 A S - 0 0 44 1,-0.1 109,-2.8 108,-0.0 2,-0.5 -0.174 51.9-128.4 -67.9 157.1 31.1 -10.8 -16.8 4 4 A L E +a 112 0A 21 126,-0.5 128,-1.6 107,-0.2 2,-0.3 -0.936 35.7 170.8-106.8 129.4 32.3 -7.3 -17.7 5 5 A N E -ab 113 132A 4 107,-2.2 109,-3.0 -2,-0.5 2,-0.4 -0.972 25.4-150.1-139.5 146.3 30.8 -5.8 -20.9 6 6 A C E -ab 114 133A 0 126,-2.6 128,-3.3 -2,-0.3 2,-0.4 -0.921 13.7-165.5-109.6 148.8 30.7 -2.4 -22.7 7 7 A I E + b 0 134A 3 107,-2.3 2,-0.3 -2,-0.4 128,-0.2 -0.993 18.9 152.3-137.3 129.9 27.8 -1.5 -24.8 8 8 A V E - b 0 135A 4 126,-2.6 128,-2.7 -2,-0.4 2,-0.4 -0.982 36.0-141.0-150.7 152.2 27.8 1.4 -27.3 9 9 A A E - b 0 136A 3 -2,-0.3 2,-0.3 126,-0.2 128,-0.2 -0.996 32.1-177.5-116.0 130.1 26.3 2.7 -30.6 10 10 A V E - b 0 137A 0 126,-2.8 128,-3.7 -2,-0.4 6,-0.2 -0.947 22.3-131.1-131.6 144.3 28.8 4.4 -32.9 11 11 A S > - 0 0 2 4,-2.0 3,-2.1 -2,-0.3 130,-0.2 -0.335 42.2 -96.3 -81.2 172.8 28.7 6.1 -36.2 12 12 A Q T 3 S+ 0 0 112 128,-2.6 129,-0.2 126,-0.4 127,-0.1 0.887 128.6 53.2 -60.7 -34.3 31.1 5.3 -39.0 13 13 A N T 3 S- 0 0 59 127,-0.3 -1,-0.3 129,-0.1 128,-0.1 0.180 125.1-105.5 -86.9 18.0 33.3 8.2 -37.9 14 14 A M < + 0 0 21 -3,-2.1 134,-2.7 1,-0.2 2,-0.2 0.603 67.7 155.2 70.2 17.8 33.3 6.7 -34.4 15 15 A G E +I 147 0B 0 132,-0.2 -4,-2.0 127,-0.2 132,-0.3 -0.504 20.0 167.9 -77.7 141.9 30.9 9.3 -33.0 16 16 A I E + 0 0 21 130,-3.2 2,-0.3 1,-0.3 131,-0.2 0.453 62.7 23.1-127.9 -10.5 28.7 8.6 -29.9 17 17 A G E -I 146 0B 8 129,-1.4 128,-2.3 5,-0.2 129,-1.6 -0.997 46.4-170.1-157.2 155.2 27.3 12.0 -28.9 18 18 A K B > S-J 21 0C 80 3,-2.7 3,-1.8 -2,-0.3 126,-0.1 -0.916 81.3 -18.5-148.0 119.8 26.5 15.5 -30.1 19 19 A N T 3 S- 0 0 141 -2,-0.3 3,-0.1 1,-0.3 125,-0.0 0.839 127.2 -52.0 52.5 37.0 25.5 18.3 -27.7 20 20 A G T 3 S+ 0 0 49 1,-0.3 -1,-0.3 0, 0.0 2,-0.2 0.552 125.9 82.2 81.4 7.7 24.7 15.8 -24.9 21 21 A D B < S-J 18 0C 110 -3,-1.8 -3,-2.7 1,-0.1 -1,-0.3 -0.764 93.2 -78.2-126.4 175.4 22.3 13.7 -27.1 22 22 A L - 0 0 42 -2,-0.2 -5,-0.2 -5,-0.2 -6,-0.1 -0.457 38.8-125.3 -69.8 152.8 22.9 10.9 -29.6 23 23 A P S S+ 0 0 23 0, 0.0 120,-0.2 0, 0.0 -1,-0.1 0.675 91.9 52.0 -74.4 -17.0 24.1 12.1 -33.0 24 24 A W S S- 0 0 10 1,-0.1 -2,-0.1 118,-0.1 3,-0.1 -0.747 97.7 -90.2-113.8 162.1 21.2 10.2 -34.8 25 25 A P - 0 0 56 0, 0.0 -1,-0.1 0, 0.0 2,-0.0 -0.269 64.6 -69.2 -65.7 160.0 17.5 10.2 -34.2 26 26 A P - 0 0 51 0, 0.0 2,-0.8 0, 0.0 0, 0.0 -0.279 42.9-159.8 -57.0 122.8 15.9 7.7 -31.8 27 27 A L > - 0 0 0 1,-0.2 4,-2.4 -3,-0.1 3,-0.4 -0.911 6.1-162.4-105.0 102.0 16.1 4.2 -33.2 28 28 A R H > S+ 0 0 135 -2,-0.8 4,-2.0 1,-0.3 -1,-0.2 0.871 85.2 45.1 -60.1 -44.8 13.5 2.4 -31.2 29 29 A N H > S+ 0 0 81 2,-0.2 4,-1.6 1,-0.2 -1,-0.3 0.810 112.2 53.6 -70.7 -26.8 14.5 -1.2 -31.9 30 30 A E H > S+ 0 0 7 -3,-0.4 4,-2.3 2,-0.2 -2,-0.2 0.907 108.5 49.5 -70.9 -42.1 18.2 -0.3 -31.2 31 31 A F H X S+ 0 0 25 -4,-2.4 4,-2.5 1,-0.2 -2,-0.2 0.882 108.7 53.0 -60.6 -40.2 17.1 1.2 -27.8 32 32 A R H X S+ 0 0 159 -4,-2.0 4,-2.8 2,-0.2 -1,-0.2 0.853 106.9 52.8 -65.8 -33.6 15.2 -2.0 -27.1 33 33 A Y H X S+ 0 0 7 -4,-1.6 4,-3.0 2,-0.2 5,-0.3 0.952 109.3 48.3 -62.8 -50.7 18.4 -4.0 -27.8 34 34 A F H X S+ 0 0 3 -4,-2.3 4,-2.4 1,-0.2 5,-0.3 0.916 113.6 48.4 -54.5 -44.8 20.3 -1.8 -25.3 35 35 A Q H X S+ 0 0 59 -4,-2.5 4,-2.1 2,-0.2 5,-0.3 0.932 113.3 45.9 -62.8 -47.5 17.5 -2.4 -22.8 36 36 A R H X S+ 0 0 109 -4,-2.8 4,-1.9 1,-0.2 -2,-0.2 0.909 115.0 47.0 -63.6 -43.5 17.4 -6.1 -23.3 37 37 A M H < S+ 0 0 25 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.927 117.8 39.5 -67.0 -45.8 21.1 -6.6 -23.2 38 38 A T H < S+ 0 0 0 -4,-2.4 -1,-0.2 -5,-0.3 -2,-0.2 0.774 121.1 43.3 -79.1 -24.5 21.7 -4.5 -20.1 39 39 A T H < S+ 0 0 42 -4,-2.1 2,-0.6 -5,-0.3 9,-0.3 0.803 88.1 95.1 -89.1 -31.2 18.7 -5.6 -18.2 40 40 A T < - 0 0 83 -4,-1.9 2,-0.2 -5,-0.3 71,-0.1 -0.479 60.5-158.5 -74.7 113.5 18.7 -9.4 -18.8 41 41 A S - 0 0 31 -2,-0.6 -2,-0.1 5,-0.2 4,-0.0 -0.593 18.1-146.7 -87.6 149.1 20.5 -11.2 -16.0 42 42 A S S S+ 0 0 84 -2,-0.2 2,-0.4 1,-0.1 -1,-0.1 0.490 87.6 59.9 -88.5 -5.1 22.0 -14.7 -16.4 43 43 A V S > S- 0 0 65 3,-0.1 3,-1.6 0, 0.0 -1,-0.1 -0.988 85.7-126.3-128.3 123.2 21.1 -15.5 -12.8 44 44 A E T 3 S+ 0 0 195 -2,-0.4 3,-0.1 1,-0.2 -2,-0.1 -0.415 98.0 29.6 -62.0 140.3 17.5 -15.5 -11.4 45 45 A G T 3 S+ 0 0 86 1,-0.3 2,-0.3 -2,-0.1 -1,-0.2 0.272 105.5 92.4 92.4 -10.5 17.4 -13.3 -8.3 46 46 A K < - 0 0 47 -3,-1.6 2,-0.3 63,-0.0 -1,-0.3 -0.816 59.1-147.6-115.3 156.1 20.1 -10.9 -9.4 47 47 A Q E -c 109 0A 84 61,-2.5 63,-2.4 -2,-0.3 2,-0.2 -0.811 23.4-112.4-112.1 159.4 20.2 -7.6 -11.4 48 48 A N E - 0 0 0 21,-0.5 23,-2.7 -9,-0.3 2,-0.5 -0.589 26.7-128.4 -84.1 155.4 22.8 -6.3 -13.7 49 49 A L E -cd 112 71A 0 62,-2.8 64,-3.1 -2,-0.2 2,-0.5 -0.906 15.0-157.1-105.0 130.6 24.9 -3.3 -12.8 50 50 A V E -cd 113 72A 0 21,-3.5 23,-2.8 -2,-0.5 2,-0.5 -0.948 7.7-164.1-108.2 126.1 25.2 -0.3 -15.2 51 51 A I E +cd 114 73A 0 62,-2.9 64,-2.8 -2,-0.5 2,-0.3 -0.920 18.1 159.2-111.0 132.9 28.2 1.9 -14.8 52 52 A M E - d 0 74A 0 21,-2.2 23,-2.5 -2,-0.5 65,-0.3 -0.996 36.9-108.0-152.0 152.6 28.4 5.3 -16.4 53 53 A G E > - d 0 75A 10 63,-2.3 4,-2.2 -2,-0.3 23,-0.1 -0.248 42.7 -99.9 -72.6 169.2 30.1 8.7 -16.2 54 54 A K H > S+ 0 0 73 21,-0.9 4,-2.0 1,-0.2 5,-0.2 0.883 120.2 47.8 -59.8 -45.9 28.4 11.8 -14.9 55 55 A K H > S+ 0 0 178 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.877 110.6 53.2 -66.6 -35.9 27.6 13.4 -18.3 56 56 A T H >> S+ 0 0 18 2,-0.2 3,-0.9 1,-0.2 4,-0.6 0.935 106.2 53.4 -64.4 -44.0 26.2 10.1 -19.5 57 57 A W H >< S+ 0 0 0 -4,-2.2 3,-1.6 1,-0.3 -2,-0.2 0.943 110.5 46.0 -53.9 -49.9 23.9 9.9 -16.5 58 58 A F H 3< S+ 0 0 112 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.616 102.6 66.3 -74.6 -7.0 22.5 13.4 -17.2 59 59 A S H << S+ 0 0 38 -3,-0.9 -1,-0.3 -4,-0.8 -2,-0.2 0.583 82.6 92.2 -86.5 -10.8 22.1 12.5 -20.9 60 60 A I S << S- 0 0 1 -3,-1.6 5,-0.1 -4,-0.6 -39,-0.0 -0.705 96.0-101.3 -80.2 131.4 19.4 10.0 -19.9 61 61 A P > - 0 0 55 0, 0.0 3,-3.0 0, 0.0 4,-0.4 -0.339 28.9-125.5 -51.5 129.9 15.9 11.4 -20.0 62 62 A E G > S+ 0 0 140 1,-0.3 3,-1.6 2,-0.2 -2,-0.0 0.823 110.4 62.1 -48.4 -37.2 14.9 12.2 -16.4 63 63 A K G 3 S+ 0 0 162 1,-0.3 -1,-0.3 0, 0.0 -3,-0.0 0.684 105.5 47.6 -64.1 -18.1 11.8 10.1 -16.8 64 64 A N G < S+ 0 0 63 -3,-3.0 4,-0.3 124,-0.1 -1,-0.3 0.355 89.0 139.3-106.1 2.6 14.1 7.1 -17.5 65 65 A R < + 0 0 60 -3,-1.6 2,-0.2 -4,-0.4 21,-0.1 -0.845 60.7 30.6-103.0 136.1 16.4 7.5 -14.5 66 66 A P S S- 0 0 45 0, 0.0 2,-0.3 0, 0.0 3,-0.1 0.661 103.6-112.7 -72.2 156.7 17.5 5.4 -12.8 67 67 A L > - 0 0 1 -2,-0.2 3,-1.3 1,-0.1 -2,-0.1 -0.411 43.3-116.5 -55.1 115.9 17.4 2.8 -15.6 68 68 A K T 3 S+ 0 0 144 -4,-0.3 -1,-0.1 -2,-0.3 3,-0.1 -0.220 89.8 17.8 -61.3 144.9 14.7 0.5 -14.3 69 69 A G T 3 S+ 0 0 36 1,-0.2 -21,-0.5 -3,-0.1 2,-0.3 0.462 111.6 85.0 78.1 1.8 15.5 -3.1 -13.5 70 70 A R S < S- 0 0 3 -3,-1.3 2,-0.5 -23,-0.1 -21,-0.2 -0.930 82.6-112.6-130.4 153.0 19.2 -2.4 -13.2 71 71 A I E -d 49 0A 19 -23,-2.7 -21,-3.5 -2,-0.3 2,-0.5 -0.803 35.8-147.0 -84.8 126.8 21.5 -1.1 -10.5 72 72 A N E +d 50 0A 0 -2,-0.5 16,-1.7 -23,-0.2 15,-1.5 -0.860 18.7 179.9-106.0 119.7 22.8 2.3 -11.6 73 73 A L E -de 51 88A 0 -23,-2.8 -21,-2.2 -2,-0.5 2,-0.4 -0.983 11.3-155.0-124.2 131.1 26.3 3.4 -10.6 74 74 A V E -de 52 89A 0 14,-2.6 16,-2.4 -2,-0.4 2,-0.5 -0.851 7.4-143.4-107.7 137.4 27.8 6.8 -11.5 75 75 A L E +de 53 90A 16 -23,-2.5 -21,-0.9 -2,-0.4 2,-0.3 -0.871 35.4 144.6 -99.9 131.9 31.5 7.5 -11.8 76 76 A S - 0 0 13 14,-2.4 16,-0.1 -2,-0.5 -2,-0.0 -0.867 39.9-157.4-168.6 133.0 32.8 10.9 -10.7 77 77 A R S S+ 0 0 187 -2,-0.3 14,-0.1 1,-0.1 -1,-0.0 0.477 98.7 37.1 -87.9 -4.6 35.9 12.3 -9.0 78 78 A E S S+ 0 0 156 13,-0.0 -1,-0.1 0, 0.0 13,-0.1 0.671 87.5 97.6-122.0 -30.3 34.1 15.4 -7.7 79 79 A L - 0 0 58 1,-0.1 -3,-0.1 12,-0.0 10,-0.0 -0.376 51.7-161.4 -62.8 142.5 30.6 14.4 -6.7 80 80 A K S S+ 0 0 194 1,-0.3 -1,-0.1 2,-0.0 9,-0.1 0.755 77.9 18.8 -93.6 -33.7 30.2 13.8 -3.0 81 81 A E S S- 0 0 145 7,-0.1 -1,-0.3 3,-0.0 3,-0.1 -0.926 96.3 -89.2-131.8 157.5 26.9 11.8 -3.4 82 82 A P - 0 0 35 0, 0.0 3,-0.2 0, 0.0 7,-0.1 -0.388 55.9 -93.9 -64.9 145.5 25.3 10.1 -6.4 83 83 A P > - 0 0 14 0, 0.0 3,-2.4 0, 0.0 -9,-0.1 -0.233 63.0 -71.7 -57.6 152.7 23.0 12.3 -8.4 84 84 A Q T 3 S+ 0 0 189 1,-0.3 3,-0.1 -3,-0.1 -19,-0.0 -0.230 124.8 19.5 -53.5 123.7 19.4 12.1 -7.4 85 85 A G T 3 S+ 0 0 35 1,-0.4 -1,-0.3 -3,-0.2 -13,-0.2 -0.092 94.3 116.3 107.3 -31.8 18.0 8.7 -8.5 86 86 A A < - 0 0 14 -3,-2.4 -1,-0.4 1,-0.1 -13,-0.1 -0.406 56.4-147.9 -71.7 147.5 21.4 6.9 -8.9 87 87 A H S S+ 0 0 96 -15,-1.5 2,-0.3 1,-0.2 -14,-0.2 0.845 72.1 13.2 -85.8 -37.2 22.1 4.0 -6.6 88 88 A F E -e 73 0A 38 -16,-1.7 -14,-2.6 -7,-0.1 2,-0.4 -0.953 55.6-153.9-140.6 158.9 25.8 4.3 -6.2 89 89 A L E +e 74 0A 41 -2,-0.3 2,-0.3 -16,-0.2 -14,-0.2 -0.999 15.4 176.6-132.7 132.8 28.8 6.6 -6.7 90 90 A S E -e 75 0A 10 -16,-2.4 -14,-2.4 -2,-0.4 3,-0.1 -0.942 30.7-137.1-131.3 160.5 32.4 5.6 -7.3 91 91 A R S S+ 0 0 155 -2,-0.3 2,-0.3 -16,-0.2 -16,-0.1 0.647 84.9 5.7 -89.8 -18.8 35.5 7.6 -8.0 92 92 A S S > S- 0 0 29 1,-0.1 4,-2.2 -16,-0.1 -1,-0.2 -0.979 74.4-105.2-158.2 164.0 36.9 5.3 -10.6 93 93 A L H > S+ 0 0 0 -2,-0.3 4,-2.9 1,-0.2 5,-0.2 0.915 119.8 53.7 -61.9 -43.3 36.2 2.1 -12.6 94 94 A D H > S+ 0 0 74 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.888 109.9 48.2 -58.4 -38.5 38.6 0.1 -10.4 95 95 A D H > S+ 0 0 67 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.884 110.9 51.2 -70.2 -37.6 36.7 1.3 -7.3 96 96 A A H X S+ 0 0 0 -4,-2.2 4,-1.4 2,-0.2 -2,-0.2 0.913 110.1 48.5 -63.8 -44.5 33.4 0.4 -8.9 97 97 A L H X S+ 0 0 20 -4,-2.9 4,-0.7 1,-0.2 -2,-0.2 0.894 110.5 51.3 -65.4 -37.3 34.5 -3.1 -9.7 98 98 A K H >X S+ 0 0 124 -4,-2.0 3,-1.0 1,-0.2 4,-0.7 0.887 105.3 57.5 -64.6 -37.2 35.9 -3.5 -6.1 99 99 A L H >< S+ 0 0 29 -4,-2.1 3,-0.9 1,-0.3 6,-0.5 0.861 100.2 56.6 -61.3 -35.2 32.5 -2.4 -4.9 100 100 A T H 3< S+ 0 0 5 -4,-1.4 -1,-0.3 1,-0.2 9,-0.2 0.729 104.6 54.5 -69.4 -18.5 30.8 -5.2 -6.8 101 101 A E H << S+ 0 0 147 -3,-1.0 -1,-0.2 -4,-0.7 -2,-0.2 0.591 90.1 94.1 -89.9 -12.1 33.0 -7.6 -4.9 102 102 A Q S XX S- 0 0 97 -3,-0.9 4,-2.6 -4,-0.7 3,-1.4 -0.400 92.9-102.7 -79.0 160.3 32.0 -6.3 -1.5 103 103 A P H 3> S+ 0 0 115 0, 0.0 4,-0.6 0, 0.0 -1,-0.1 0.750 114.7 64.5 -57.9 -27.4 29.1 -8.0 0.4 104 104 A E H 34 S+ 0 0 106 1,-0.2 -4,-0.1 2,-0.1 -5,-0.1 0.850 122.7 16.2 -68.5 -30.3 26.5 -5.4 -0.4 105 105 A L H X> S+ 0 0 2 -3,-1.4 4,-2.5 -6,-0.5 3,-2.2 0.607 101.8 91.0-112.5 -17.5 26.6 -6.1 -4.1 106 106 A A H 3< S+ 0 0 35 -4,-2.6 -2,-0.1 1,-0.3 -1,-0.1 0.803 101.4 30.9 -52.2 -36.8 28.4 -9.5 -4.2 107 107 A N T 3< S+ 0 0 112 -4,-0.6 -1,-0.3 -5,-0.1 -2,-0.1 0.188 120.8 53.4-108.8 15.5 25.1 -11.4 -4.1 108 108 A K T <4 S+ 0 0 101 -3,-2.2 -61,-2.5 -8,-0.2 2,-0.4 0.662 94.5 71.6-117.3 -30.8 23.0 -8.8 -5.9 109 109 A V E < + c 0 47A 0 -4,-2.5 -61,-0.2 -9,-0.2 3,-0.1 -0.777 41.8 167.7-100.0 135.5 24.9 -8.2 -9.1 110 110 A D E + 0 0 11 -63,-2.4 -108,-2.7 1,-0.4 -62,-0.2 0.619 67.0 14.0 -99.9 -97.1 25.2 -10.5 -12.1 111 111 A M E - 0 0 36 -110,-0.2 -62,-2.8 -109,-0.1 2,-0.5 -0.462 66.0-141.0 -82.3 151.8 26.7 -8.8 -15.2 112 112 A V E -ac 4 49A 4 -109,-2.8 -107,-2.2 -64,-0.2 2,-0.5 -0.958 17.4-167.2-110.8 128.1 28.4 -5.4 -15.3 113 113 A W E -ac 5 50A 3 -64,-3.1 -62,-2.9 -2,-0.5 2,-0.6 -0.974 10.6-151.7-120.3 122.1 27.7 -3.1 -18.2 114 114 A I E +ac 6 51A 0 -109,-3.0 -107,-2.3 -2,-0.5 -62,-0.2 -0.833 15.6 178.5 -91.6 124.2 29.7 -0.0 -19.0 115 115 A V - 0 0 1 -64,-2.8 -63,-0.1 -2,-0.6 2,-0.1 0.123 36.4-162.8-119.9 21.9 27.6 2.5 -20.8 116 116 A G - 0 0 1 -65,-0.3 -63,-2.3 1,-0.3 -1,-0.4 -0.396 54.0-140.8 111.3 175.6 29.9 5.5 -21.4 117 117 A G > - 0 0 17 -65,-0.3 4,-2.7 -2,-0.1 3,-0.3 0.449 58.9 -96.3 -90.3-151.2 31.2 8.0 -21.9 118 118 A S H > S+ 0 0 39 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.843 120.7 46.3 -50.1 -49.0 34.4 8.0 -23.8 119 119 A S H > S+ 0 0 91 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.896 113.6 50.0 -67.0 -38.4 36.9 8.0 -20.9 120 120 A V H > S+ 0 0 6 -3,-0.3 4,-2.6 2,-0.2 -2,-0.2 0.919 110.9 49.3 -64.1 -45.5 35.0 5.3 -19.2 121 121 A Y H X S+ 0 0 2 -4,-2.7 4,-3.1 2,-0.2 -2,-0.2 0.942 111.1 49.7 -56.7 -47.2 34.9 3.1 -22.3 122 122 A K H X S+ 0 0 118 -4,-2.5 4,-1.3 1,-0.2 -2,-0.2 0.924 111.8 48.2 -61.4 -43.0 38.7 3.6 -22.8 123 123 A E H X S+ 0 0 68 -4,-2.3 4,-0.9 1,-0.2 3,-0.5 0.941 114.2 46.4 -61.7 -47.0 39.4 2.7 -19.2 124 124 A A H >< S+ 0 0 0 -4,-2.6 3,-1.0 1,-0.2 -2,-0.2 0.925 107.6 56.4 -63.1 -44.8 37.2 -0.4 -19.4 125 125 A M H 3< S+ 0 0 7 -4,-3.1 -1,-0.2 1,-0.3 -2,-0.2 0.787 112.0 41.8 -61.9 -27.7 38.6 -1.5 -22.7 126 126 A N H 3< S+ 0 0 83 -4,-1.3 -1,-0.3 -3,-0.5 -2,-0.2 0.553 86.5 116.5 -95.6 -11.6 42.2 -1.6 -21.4 127 127 A H S << S- 0 0 49 -3,-1.0 -3,-0.0 -4,-0.9 -4,-0.0 -0.328 75.4-103.8 -58.4 134.2 41.3 -3.2 -18.0 128 128 A P S S+ 0 0 93 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.248 77.6 32.1 -59.2 148.0 42.9 -6.6 -17.6 129 129 A G S S- 0 0 23 -3,-0.1 2,-0.3 2,-0.1 55,-0.1 -0.461 100.8 -16.3 107.8-174.3 40.8 -9.8 -18.1 130 130 A H + 0 0 84 56,-0.2 -126,-0.5 -2,-0.1 2,-0.3 -0.520 65.1 165.5 -71.1 125.6 37.8 -11.0 -20.1 131 131 A L E - F 0 184A 2 53,-1.9 53,-2.2 -2,-0.3 2,-0.4 -0.998 21.4-157.3-143.1 139.5 35.8 -8.2 -21.6 132 132 A K E -bF 5 183A 31 -128,-1.6 -126,-2.6 -2,-0.3 2,-0.6 -0.955 6.3-152.8-115.0 140.5 33.1 -8.1 -24.4 133 133 A L E -bF 6 182A 1 49,-2.4 49,-2.6 -2,-0.4 2,-0.9 -0.957 1.8-159.8-112.5 117.4 32.2 -5.0 -26.4 134 134 A F E -bF 7 181A 4 -128,-3.3 -126,-2.6 -2,-0.6 2,-0.5 -0.869 22.3-177.8 -95.0 103.5 28.7 -4.9 -27.8 135 135 A V E -bF 8 180A 1 45,-2.2 45,-2.6 -2,-0.9 2,-0.7 -0.912 21.2-159.2-114.2 118.5 29.0 -2.4 -30.6 136 136 A T E -bF 9 179A 0 -128,-2.7 -126,-2.8 -2,-0.5 2,-0.8 -0.885 17.2-148.8 -91.9 117.2 26.2 -1.2 -32.8 137 137 A R E -bF 10 178A 56 41,-3.1 41,-2.0 -2,-0.7 2,-0.6 -0.817 2.9-155.3 -89.9 108.4 27.7 0.1 -36.0 138 138 A I E - F 0 177A 1 -128,-3.7 2,-1.7 -2,-0.8 -126,-0.4 -0.796 16.6-140.0 -83.0 118.1 25.5 2.9 -37.3 139 139 A M S S+ 0 0 63 37,-2.8 2,-0.3 -2,-0.6 37,-0.2 -0.320 70.9 66.5 -90.4 56.5 26.4 2.8 -41.0 140 140 A Q S S- 0 0 73 -2,-1.7 -128,-2.6 35,-0.1 2,-0.4 -0.959 84.2-103.5-158.9 157.8 26.5 6.5 -41.7 141 141 A D - 0 0 111 -2,-0.3 2,-0.4 -130,-0.2 -2,-0.1 -0.739 38.4-174.7 -83.3 137.8 28.7 9.5 -40.7 142 142 A F - 0 0 36 -2,-0.4 2,-0.2 -118,-0.0 -127,-0.2 -1.000 33.9-106.7-133.6 136.6 27.1 11.8 -38.2 143 143 A E + 0 0 158 -2,-0.4 2,-0.3 -120,-0.2 -2,-0.0 -0.443 53.8 171.5 -57.4 126.2 28.4 15.1 -36.8 144 144 A S - 0 0 16 -2,-0.2 -126,-0.3 1,-0.1 3,-0.1 -0.979 39.3-164.8-142.2 150.8 29.6 14.3 -33.3 145 145 A D S S+ 0 0 80 -128,-2.3 2,-0.4 -2,-0.3 -127,-0.2 0.478 83.1 51.3-111.5 -10.0 31.5 15.9 -30.5 146 146 A T E S-I 17 0B 58 -129,-1.6 -130,-3.2 -28,-0.0 -129,-1.4 -0.997 71.6-165.0-131.2 138.9 32.3 12.8 -28.5 147 147 A F E -I 15 0B 91 -2,-0.4 -132,-0.2 -132,-0.3 -133,-0.1 -0.842 23.3-114.1-127.2 154.1 33.8 9.6 -29.8 148 148 A F - 0 0 5 -134,-2.7 3,-0.1 -2,-0.3 -30,-0.1 -0.676 46.1-105.0 -82.1 138.9 34.4 5.9 -29.0 149 149 A P - 0 0 23 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.244 45.7 -89.3 -61.0 151.8 38.0 5.0 -28.5 150 150 A E - 0 0 154 1,-0.1 2,-0.6 -3,-0.1 -3,-0.0 -0.393 40.5-128.5 -63.9 138.9 39.7 3.0 -31.3 151 151 A I - 0 0 17 -3,-0.1 2,-0.9 -2,-0.1 -1,-0.1 -0.816 13.5-131.3 -90.1 124.1 39.2 -0.7 -30.9 152 152 A D > - 0 0 84 -2,-0.6 4,-2.8 1,-0.1 -1,-0.0 -0.683 18.4-161.7 -75.9 108.0 42.5 -2.7 -31.2 153 153 A L T 4 S+ 0 0 103 -2,-0.9 5,-0.2 1,-0.2 -1,-0.1 0.388 86.6 51.5 -82.7 2.9 41.5 -5.4 -33.6 154 154 A E T 4 S+ 0 0 158 3,-0.1 -1,-0.2 0, 0.0 -2,-0.1 0.807 114.5 42.5 -89.9 -48.7 44.4 -7.7 -32.7 155 155 A K T 4 S+ 0 0 65 1,-0.1 2,-0.4 29,-0.1 31,-0.3 0.851 121.2 44.9 -64.3 -40.6 43.6 -7.5 -29.0 156 156 A Y S < S- 0 0 1 -4,-2.8 2,-0.4 28,-0.1 28,-0.2 -0.889 74.6-154.3-106.3 137.1 39.9 -7.8 -29.6 157 157 A K E -G 183 0A 129 26,-2.6 26,-2.0 -2,-0.4 2,-0.4 -0.929 18.8-123.9-111.0 138.4 38.4 -10.3 -32.0 158 158 A L E -G 182 0A 84 -2,-0.4 24,-0.3 24,-0.2 3,-0.0 -0.633 25.6-130.2 -73.7 126.8 35.0 -9.8 -33.7 159 159 A L - 0 0 39 22,-3.4 22,-0.5 -2,-0.4 3,-0.1 -0.644 10.8-139.6 -80.1 130.6 32.8 -12.8 -32.9 160 160 A P S S- 0 0 125 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.889 83.0 -6.0 -64.1 -39.3 31.3 -14.0 -36.2 161 161 A E - 0 0 143 -3,-0.0 5,-0.1 19,-0.0 19,-0.0 -0.923 69.1-156.4-141.5 168.0 27.9 -14.6 -34.6 162 162 A Y > - 0 0 55 3,-0.5 3,-1.9 -2,-0.3 2,-0.0 -0.981 30.0-100.9-148.4 135.1 26.7 -14.3 -31.1 163 163 A P T 3 S+ 0 0 115 0, 0.0 3,-0.1 0, 0.0 -2,-0.0 -0.341 107.3 14.4 -59.1 134.0 23.7 -15.9 -29.3 164 164 A G T 3 S+ 0 0 53 1,-0.2 2,-0.5 -2,-0.0 0, 0.0 0.466 104.3 106.0 85.1 6.5 20.8 -13.5 -29.0 165 165 A V < - 0 0 18 -3,-1.9 -3,-0.5 14,-0.0 -1,-0.2 -0.975 69.3-125.9-126.0 124.8 22.2 -11.0 -31.4 166 166 A L - 0 0 98 -2,-0.5 13,-0.5 1,-0.1 4,-0.1 -0.424 14.3-161.4 -66.7 141.6 20.8 -10.5 -34.9 167 167 A S + 0 0 63 -2,-0.1 -1,-0.1 11,-0.1 3,-0.1 0.727 59.5 88.2 -96.5 -26.2 23.4 -10.7 -37.7 168 168 A D S S- 0 0 128 1,-0.1 11,-0.3 10,-0.1 2,-0.1 -0.316 89.9 -89.9 -76.5 155.2 21.6 -9.0 -40.6 169 169 A V - 0 0 77 9,-0.1 2,-0.3 7,-0.1 9,-0.2 -0.436 44.5-153.1 -59.3 133.4 21.7 -5.3 -41.3 170 170 A Q E -H 177 0A 42 7,-3.4 7,-2.5 -2,-0.1 2,-0.3 -0.702 7.2-160.8-105.1 158.7 18.9 -3.5 -39.5 171 171 A E E +H 176 0A 114 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.964 16.6 162.4-147.2 129.5 17.3 -0.3 -40.7 172 172 A E E > S+H 175 0A 31 3,-1.9 3,-2.3 -2,-0.3 -2,-0.0 -0.985 75.1 1.4-140.7 141.2 15.2 2.3 -38.8 173 173 A K T 3 S- 0 0 125 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.834 129.6 -61.2 50.7 35.6 14.4 5.9 -39.9 174 174 A G T 3 S+ 0 0 47 1,-0.2 2,-0.5 0, 0.0 -1,-0.3 0.651 111.4 122.2 70.3 13.7 16.4 5.3 -43.0 175 175 A I E < - H 0 172A 7 -3,-2.3 -3,-1.9 -35,-0.0 2,-0.3 -0.947 52.8-147.2-111.4 120.6 19.5 4.6 -41.0 176 176 A K E + H 0 171A 105 -2,-0.5 -37,-2.8 -37,-0.2 2,-0.3 -0.626 25.5 165.6 -84.7 142.9 21.2 1.2 -41.5 177 177 A Y E -FH 138 170A 2 -7,-2.5 -7,-3.4 -2,-0.3 2,-0.3 -0.992 20.8-153.6-153.0 160.3 23.0 -0.5 -38.6 178 178 A K E -F 137 0A 78 -41,-2.0 -41,-3.1 -2,-0.3 2,-0.5 -0.985 18.9-125.2-139.5 145.8 24.5 -3.8 -37.5 179 179 A F E -F 136 0A 21 -13,-0.5 2,-0.3 -2,-0.3 -43,-0.2 -0.782 31.3-179.8 -92.2 130.3 25.1 -5.4 -34.1 180 180 A E E -F 135 0A 21 -45,-2.6 -45,-2.2 -2,-0.5 2,-0.4 -0.939 15.2-157.2-127.5 149.6 28.6 -6.6 -33.4 181 181 A V E -F 134 0A 4 -22,-0.5 -22,-3.4 -2,-0.3 2,-0.3 -0.997 10.3-172.7-128.4 127.8 30.3 -8.3 -30.5 182 182 A Y E -FG 133 158A 9 -49,-2.6 -49,-2.4 -2,-0.4 2,-0.3 -0.845 5.7-168.4-112.8 152.7 34.0 -8.2 -29.8 183 183 A E E -FG 132 157A 48 -26,-2.0 -26,-2.6 -2,-0.3 2,-0.3 -0.999 14.0-175.5-142.1 144.8 35.9 -10.1 -27.1 184 184 A K E -F 131 0A 4 -53,-2.2 -53,-1.9 -2,-0.3 -28,-0.1 -0.967 13.5-165.8-129.2 151.9 39.3 -10.2 -25.5 185 185 A N 0 0 118 -2,-0.3 -55,-0.1 -30,-0.3 -1,-0.1 0.558 360.0 360.0-103.3 -19.7 40.5 -12.8 -22.9 186 186 A D 0 0 121 -31,-0.3 -56,-0.2 -58,-0.1 -1,-0.1 0.307 360.0 360.0 23.3 360.0 43.5 -10.5 -22.0 187 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 188 201 A X 0 0 57 0, 0.0 -124,-0.1 0, 0.0 -157,-0.1 0.000 360.0 360.0 360.0 360.0 16.3 3.3 -21.5