==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE/TRANSFERASE INHIBITOR 19-AUG-13 4MBI . COMPND 2 MOLECULE: SERINE/THREONINE-PROTEIN KINASE PIM-1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.AZEVEDO,T.O.FISCHMANN . 274 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13613.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 171 62.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 51 18.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 5.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 24 8.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 74 27.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 2 0 2 1 1 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 2 1 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 33 A P 0 0 156 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-101.7 8.9 40.6 17.6 2 34 A L - 0 0 148 1,-0.1 2,-4.0 3,-0.0 76,-0.0 0.891 360.0-102.8 96.2 51.8 7.0 40.6 14.2 3 35 A E S > S+ 0 0 37 1,-0.2 3,-1.0 2,-0.1 2,-0.2 0.001 97.8 87.7 62.2 -43.8 8.9 40.7 10.9 4 36 A S T 3 + 0 0 113 -2,-4.0 -1,-0.2 1,-0.2 3,-0.1 -0.254 60.4 91.6 -92.6 49.9 8.4 44.3 9.8 5 37 A Q T 3 S+ 0 0 63 -2,-0.2 21,-1.9 21,-0.0 22,-0.7 0.240 87.0 62.9-100.7 -0.6 11.5 45.5 11.8 6 38 A Y E < S-A 25 0A 8 -3,-1.0 2,-0.5 19,-0.3 19,-0.2 -0.932 81.0-139.2-114.3 146.7 13.2 44.7 8.3 7 39 A Q E -A 24 0A 121 17,-2.6 17,-1.6 -2,-0.3 2,-0.4 -0.926 22.5-132.2-107.2 130.0 12.4 46.5 5.1 8 40 A V E +A 23 0A 94 -2,-0.5 15,-0.2 15,-0.2 3,-0.1 -0.652 29.5 170.2 -90.6 130.9 12.2 44.3 2.0 9 41 A G E - 0 0 27 13,-3.4 3,-0.1 -2,-0.4 -1,-0.1 -0.200 44.4 -22.6-110.5-152.0 14.0 45.1 -1.2 10 42 A P E - 0 0 93 0, 0.0 12,-3.0 0, 0.0 2,-0.3 -0.146 66.7-101.6 -56.4 147.5 14.8 43.2 -4.5 11 43 A L E -A 21 0A 91 10,-0.2 10,-0.3 1,-0.2 3,-0.1 -0.592 31.8-165.2 -62.9 125.5 14.8 39.5 -4.9 12 44 A L E - 0 0 100 8,-2.9 2,-0.3 1,-0.4 9,-0.2 0.859 57.9 -50.9 -86.0 -40.1 18.5 38.6 -4.9 13 45 A G E -A 20 0A 25 7,-1.6 7,-3.0 -3,-0.1 -1,-0.4 -0.957 47.0-142.1-177.9 171.7 18.0 35.0 -6.2 14 46 A S E +A 19 0A 76 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.993 38.4 104.3-147.0 150.5 16.1 31.8 -5.7 15 47 A G E > S-A 18 0A 44 3,-2.2 3,-2.3 -2,-0.3 -2,-0.0 -0.911 85.9 -25.2 177.4-146.0 16.8 28.1 -6.0 16 48 A G T 3 S+ 0 0 94 1,-0.3 3,-0.1 -2,-0.3 -2,-0.0 0.611 130.1 63.0 -67.4 -14.7 17.5 25.1 -3.8 17 49 A F T 3 S- 0 0 71 1,-0.4 -1,-0.3 20,-0.0 2,-0.2 0.423 115.9-115.6 -82.9 -0.5 18.6 27.5 -1.2 18 50 A G E < -A 15 0A 11 -3,-2.3 -3,-2.2 17,-0.1 2,-0.5 -0.640 50.2 -45.6 96.2-162.0 15.1 29.0 -1.1 19 51 A S E -AB 14 36A 43 17,-2.1 17,-3.0 -5,-0.2 2,-0.4 -0.954 57.3-164.5-109.7 129.2 14.3 32.6 -2.1 20 52 A V E -AB 13 35A 20 -7,-3.0 -8,-2.9 -2,-0.5 -7,-1.6 -0.969 3.9-167.3-119.7 130.5 16.6 35.4 -0.8 21 53 A Y E -AB 11 34A 74 13,-2.4 13,-2.7 -2,-0.4 2,-0.3 -0.808 26.9-111.1-115.8 155.5 15.8 39.1 -0.8 22 54 A S E + B 0 33A 18 -12,-3.0 -13,-3.4 -2,-0.3 2,-0.3 -0.643 49.2 171.1 -78.0 139.9 17.8 42.2 -0.2 23 55 A G E -AB 8 32A 0 9,-2.5 9,-2.9 -2,-0.3 2,-0.4 -0.944 30.4-144.6-149.2 165.5 16.8 43.9 3.1 24 56 A I E -AB 7 31A 54 -17,-1.6 -17,-2.6 -2,-0.3 2,-0.5 -0.985 24.4-127.6-135.6 122.1 17.6 46.6 5.6 25 57 A R E >>> -AB 6 30A 57 5,-2.7 4,-1.1 -2,-0.4 3,-0.9 -0.612 19.5-151.1 -65.4 118.1 17.1 46.2 9.3 26 58 A V T 345S+ 0 0 84 -21,-1.9 -1,-0.2 -2,-0.5 -20,-0.1 0.790 87.1 72.6 -64.5 -27.8 15.1 49.4 10.0 27 59 A S T 345S- 0 0 84 -22,-0.7 -1,-0.2 1,-0.2 -21,-0.1 0.790 127.8 -6.0 -57.7 -35.6 16.5 49.6 13.6 28 60 A D T <45S- 0 0 82 -3,-0.9 -1,-0.2 2,-0.1 -2,-0.2 0.092 95.4-107.0-150.9 25.0 19.9 50.7 12.4 29 61 A N T <5 + 0 0 127 -4,-1.1 -3,-0.2 1,-0.2 3,-0.0 0.626 59.8 166.2 50.9 20.7 19.9 50.5 8.5 30 62 A L E < -B 25 0A 60 -5,-0.6 -5,-2.7 -6,-0.1 -1,-0.2 -0.449 40.2-116.0 -70.2 126.9 22.0 47.4 8.6 31 63 A P E +B 24 0A 43 0, 0.0 59,-0.8 0, 0.0 2,-0.3 -0.331 45.2 171.6 -55.7 139.1 22.1 45.6 5.3 32 64 A V E -BC 23 89A 0 -9,-2.9 -9,-2.5 57,-0.2 2,-0.5 -0.960 33.6-130.7-145.9 165.0 20.6 42.1 5.5 33 65 A A E -BC 22 88A 12 55,-3.2 55,-2.7 -2,-0.3 2,-0.7 -0.980 18.9-152.1-116.3 127.8 19.6 39.2 3.4 34 66 A I E -BC 21 87A 6 -13,-2.7 -13,-2.4 -2,-0.5 2,-0.5 -0.887 14.2-167.7-101.8 105.9 16.1 37.8 4.0 35 67 A K E -BC 20 86A 2 51,-2.9 51,-2.8 -2,-0.7 2,-0.5 -0.829 3.5-166.0 -93.9 125.2 15.9 34.1 3.2 36 68 A H E -BC 19 85A 49 -17,-3.0 -17,-2.1 -2,-0.5 2,-0.4 -0.944 5.9-177.7-103.0 130.7 12.6 32.2 2.9 37 69 A V E - C 0 84A 21 47,-2.1 47,-2.1 -2,-0.5 2,-0.2 -0.993 25.7-127.8-123.4 126.9 12.4 28.4 2.9 38 70 A E E > - C 0 83A 89 -2,-0.4 3,-1.2 45,-0.2 45,-0.3 -0.524 15.7-133.1 -69.3 134.3 9.1 26.5 2.5 39 71 A K G > S+ 0 0 44 43,-2.5 3,-1.9 1,-0.2 44,-0.1 0.855 103.4 67.5 -55.5 -35.0 8.7 23.8 5.2 40 72 A D G 3 S+ 0 0 150 42,-0.5 -1,-0.2 1,-0.3 43,-0.1 0.794 100.4 47.0 -54.5 -36.0 7.7 21.4 2.5 41 73 A R G < S+ 0 0 180 -3,-1.2 2,-0.7 2,-0.0 -1,-0.3 0.186 85.9 103.0 -97.5 15.2 11.2 21.4 1.0 42 74 A I < + 0 0 24 -3,-1.9 3,-0.1 1,-0.1 -5,-0.0 -0.877 36.5 167.0 -96.1 112.2 13.0 20.9 4.2 43 75 A S + 0 0 107 -2,-0.7 2,-0.6 1,-0.2 -1,-0.1 0.639 63.6 60.8 -92.6 -18.6 14.1 17.3 4.5 44 76 A D + 0 0 66 112,-0.1 12,-2.3 2,-0.0 13,-0.4 -0.893 64.6 177.5-122.9 105.4 16.5 17.8 7.4 45 77 A W E +E 55 0B 57 -2,-0.6 2,-0.2 10,-0.2 8,-0.1 -0.665 2.2 175.7-101.1 156.5 15.3 19.0 10.7 46 78 A G E -E 54 0B 18 8,-3.2 8,-1.2 -2,-0.2 2,-0.3 -0.710 24.4-115.6-136.3-170.9 17.1 19.6 14.0 47 79 A E E -E 53 0B 120 6,-0.2 6,-0.2 -2,-0.2 3,-0.0 -0.993 17.4-126.5-136.0 150.0 16.2 21.0 17.4 48 80 A L > - 0 0 13 4,-2.0 3,-4.8 -2,-0.3 4,-0.4 -0.731 35.0-108.7 -91.2 135.6 17.5 24.0 19.2 49 81 A P T 3 S+ 0 0 126 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 0.804 120.8 64.8 -23.9 -46.9 18.8 23.5 22.8 50 82 A N T 3 S- 0 0 136 1,-0.1 -3,-0.0 2,-0.1 0, 0.0 0.685 122.4-104.1 -54.3 -26.7 15.6 25.3 23.9 51 83 A G S < S+ 0 0 51 -3,-4.8 2,-0.3 1,-0.3 -1,-0.1 0.428 72.8 137.0 115.3 1.3 13.4 22.4 22.5 52 84 A T - 0 0 61 -4,-0.4 -4,-2.0 1,-0.1 2,-1.0 -0.617 56.7-123.3 -90.9 142.4 12.0 23.8 19.2 53 85 A R E +E 47 0B 153 -2,-0.3 -6,-0.2 -6,-0.2 -1,-0.1 -0.715 47.8 163.7 -83.1 100.7 11.9 21.8 16.0 54 86 A V E -E 46 0B 0 -8,-1.2 -8,-3.2 -2,-1.0 2,-0.1 -0.687 44.4 -86.2-112.4 165.8 13.9 24.0 13.5 55 87 A P E >> -E 45 0B 7 0, 0.0 4,-1.2 0, 0.0 3,-0.6 -0.394 38.0-120.5 -65.6 153.8 15.5 23.4 10.1 56 88 A M H 3> S+ 0 0 23 -12,-2.3 4,-2.8 1,-0.2 5,-0.3 0.846 110.3 69.2 -68.7 -32.3 19.0 22.0 10.4 57 89 A E H 3> S+ 0 0 23 -13,-0.4 4,-2.7 1,-0.2 -1,-0.2 0.904 101.4 47.4 -47.9 -43.6 20.3 25.1 8.4 58 90 A V H <> S+ 0 0 0 -3,-0.6 4,-1.8 1,-0.2 -1,-0.2 0.842 109.6 51.4 -72.4 -38.2 19.4 27.2 11.5 59 91 A V H X S+ 0 0 21 -4,-1.2 4,-1.8 2,-0.2 -1,-0.2 0.937 114.7 44.0 -57.2 -45.5 21.1 24.8 14.0 60 92 A L H X S+ 0 0 0 -4,-2.8 4,-1.3 1,-0.2 -2,-0.2 0.935 113.2 50.4 -72.9 -44.9 24.3 24.8 11.8 61 93 A L H X S+ 0 0 4 -4,-2.7 4,-1.4 -5,-0.3 13,-0.4 0.839 108.0 53.2 -58.1 -38.6 24.2 28.6 11.3 62 94 A K H < S+ 0 0 106 -4,-1.8 3,-0.3 1,-0.2 -1,-0.2 0.915 108.1 51.2 -68.0 -40.3 23.8 29.2 15.1 63 95 A K H < S+ 0 0 94 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.753 119.5 34.8 -63.7 -27.2 26.8 27.0 15.8 64 96 A V H >< S+ 0 0 0 -4,-1.3 3,-0.7 -3,-0.2 -1,-0.2 0.496 99.8 77.7-105.6 -7.9 29.0 28.9 13.3 65 97 A S T 3< + 0 0 12 -4,-1.4 -1,-0.1 -3,-0.3 -2,-0.1 0.350 52.9 110.3 -88.7 6.3 27.6 32.4 13.7 66 98 A S T 3 S- 0 0 82 -3,-0.2 -1,-0.2 -4,-0.2 -2,-0.1 0.755 82.2-132.0 -49.7 -29.5 29.5 33.1 17.0 67 99 A G S < S+ 0 0 29 -3,-0.7 2,-0.1 1,-0.1 -2,-0.1 0.633 81.4 88.3 58.1 146.0 31.5 35.6 14.8 68 100 A F S S+ 0 0 201 3,-0.1 2,-0.3 1,-0.0 -2,-0.1 0.451 73.3 114.4 -83.4 153.2 33.8 37.0 13.5 69 101 A S S S- 0 0 21 2,-0.2 4,-0.1 -2,-0.1 53,-0.1 -0.956 78.5 -94.5-164.4 175.0 34.4 34.6 10.7 70 102 A G S S+ 0 0 19 -2,-0.3 82,-2.2 48,-0.1 2,-0.4 -0.166 95.0 96.6 -92.5 32.8 34.3 34.1 6.9 71 103 A V B S-f 152 0C 0 80,-0.3 2,-0.5 -7,-0.2 -2,-0.2 -0.982 85.2-115.6-115.9 134.4 30.8 32.8 7.2 72 104 A I - 0 0 7 80,-2.0 2,-0.1 -2,-0.4 -2,-0.1 -0.595 43.7-130.3 -65.6 121.8 27.8 35.0 6.7 73 105 A R - 0 0 66 -2,-0.5 16,-1.9 -4,-0.1 2,-0.7 -0.425 1.2-123.9 -85.7 148.1 26.1 35.0 10.1 74 106 A L E +D 88 0A 18 -13,-0.4 14,-0.2 14,-0.2 3,-0.1 -0.833 26.0 179.9 -88.3 116.0 22.5 34.4 11.1 75 107 A L E - 0 0 59 12,-2.7 2,-0.3 -2,-0.7 13,-0.2 0.788 64.9 -21.6 -88.8 -31.9 21.3 37.5 12.9 76 108 A D E -D 87 0A 57 11,-1.5 11,-3.3 2,-0.0 -1,-0.3 -0.968 56.1-155.5-168.0 160.8 17.7 36.2 13.6 77 109 A W E -D 86 0A 49 -2,-0.3 2,-0.3 9,-0.2 9,-0.3 -0.961 6.4-158.8-143.4 161.2 15.2 33.7 12.3 78 110 A F E -D 85 0A 25 7,-2.9 7,-2.9 -2,-0.3 2,-0.3 -0.997 13.0-132.7-140.2 143.6 11.3 33.5 12.4 79 111 A E E -D 84 0A 100 -2,-0.3 5,-0.2 5,-0.2 -25,-0.0 -0.748 22.6-176.0 -92.9 145.1 8.8 30.7 12.0 80 112 A R - 0 0 99 3,-2.7 -41,-0.1 -2,-0.3 3,-0.0 -0.843 43.2 -97.9-126.9 169.4 5.7 30.9 9.7 81 113 A P S S+ 0 0 108 0, 0.0 3,-0.1 0, 0.0 -1,-0.0 0.893 121.5 10.1 -53.2 -38.3 2.8 28.6 9.1 82 114 A D S S+ 0 0 120 1,-0.1 -43,-2.5 -43,-0.1 -42,-0.5 0.340 130.4 30.3-125.0 5.5 4.4 27.2 5.9 83 115 A S E -C 38 0A 20 -45,-0.3 -3,-2.7 -44,-0.1 2,-0.4 -0.970 63.0-125.6-157.0 162.4 8.0 28.6 5.9 84 116 A F E -CD 37 79A 1 -47,-2.1 -47,-2.1 -2,-0.3 2,-0.5 -0.908 21.2-148.4-110.1 147.2 10.9 29.8 8.0 85 117 A V E -CD 36 78A 0 -7,-2.9 -7,-2.9 -2,-0.4 2,-0.4 -0.984 10.4-164.1-118.1 124.1 12.4 33.2 7.5 86 118 A L E -CD 35 77A 2 -51,-2.8 -51,-2.9 -2,-0.5 2,-0.7 -0.922 8.1-153.2-109.9 129.9 16.2 33.7 8.2 87 119 A I E +CD 34 76A 0 -11,-3.3 -12,-2.7 -2,-0.4 -11,-1.5 -0.893 26.8 171.3-104.6 105.1 17.8 37.1 8.6 88 120 A L E -CD 33 74A 15 -55,-2.7 -55,-3.2 -2,-0.7 -14,-0.2 -0.741 35.0 -95.8-111.1 163.0 21.4 36.9 7.5 89 121 A E E -C 32 0A 47 -16,-1.9 -57,-0.2 -2,-0.3 -1,-0.1 -0.338 32.5-154.0 -78.6 160.9 24.0 39.6 7.0 90 122 A R - 0 0 41 -59,-0.8 2,-0.1 -67,-0.1 -1,-0.0 -0.933 6.4-142.6-139.8 112.7 24.7 41.1 3.7 91 123 A P - 0 0 16 0, 0.0 3,-0.1 0, 0.0 52,-0.1 -0.425 26.0-122.9 -64.4 144.4 27.9 42.7 2.4 92 124 A E S S+ 0 0 106 1,-0.3 2,-0.1 -2,-0.1 52,-0.1 -0.991 93.3 27.2-131.7 127.7 27.6 45.8 0.1 93 125 A P S S+ 0 0 45 0, 0.0 52,-1.5 0, 0.0 53,-0.5 0.677 91.3 162.9 -82.9 158.7 28.9 45.7 -2.6 94 126 A V E +G 144 0C 44 50,-0.2 2,-0.3 -3,-0.1 50,-0.2 -0.981 23.2 177.8-147.9 143.0 28.9 42.0 -3.3 95 127 A Q E -G 143 0C 37 48,-1.6 48,-2.2 -2,-0.3 2,-0.1 -0.974 33.0-118.3-147.5 136.8 29.2 39.5 -6.1 96 128 A D E > -G 142 0C 43 -2,-0.3 4,-2.8 46,-0.2 46,-0.2 -0.425 27.5-118.1 -76.7 148.7 29.2 35.7 -5.8 97 129 A L H > S+ 0 0 0 44,-2.4 4,-2.6 41,-0.8 42,-0.2 0.845 113.9 59.7 -59.6 -30.9 32.4 34.0 -6.9 98 130 A F H > S+ 0 0 80 40,-1.0 4,-2.7 43,-0.3 -1,-0.2 0.950 110.3 39.3 -58.4 -53.5 30.4 32.2 -9.6 99 131 A D H > S+ 0 0 71 -3,-0.2 4,-2.1 1,-0.2 -2,-0.2 0.912 114.0 55.6 -66.5 -38.3 29.3 35.5 -11.2 100 132 A F H X S+ 0 0 3 -4,-2.8 4,-2.1 2,-0.2 -2,-0.2 0.902 112.0 43.0 -55.9 -41.4 32.8 36.9 -10.6 101 133 A I H X S+ 0 0 8 -4,-2.6 4,-2.9 2,-0.2 -2,-0.2 0.900 109.7 55.5 -75.6 -43.8 34.3 33.9 -12.5 102 134 A T H < S+ 0 0 100 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.872 115.9 41.7 -48.7 -40.8 31.7 34.0 -15.3 103 135 A E H < S+ 0 0 135 -4,-2.1 -2,-0.2 -5,-0.2 -1,-0.2 0.853 127.3 25.5 -82.2 -39.2 32.8 37.7 -15.8 104 136 A R H < S- 0 0 119 -4,-2.1 -3,-0.2 1,-0.3 -2,-0.2 0.612 90.4-149.9-105.1 -9.7 36.5 37.5 -15.4 105 137 A G < + 0 0 28 -4,-2.9 101,-0.3 -5,-0.2 -1,-0.3 -0.407 64.4 13.1 73.6-155.1 37.3 33.9 -16.5 106 138 A A S S- 0 0 35 99,-0.4 2,-0.3 98,-0.1 98,-0.2 -0.247 85.6-125.2 -55.3 132.7 40.3 32.2 -15.0 107 139 A L - 0 0 11 96,-3.1 -1,-0.1 95,-0.1 -2,-0.0 -0.646 22.8-103.6 -86.1 142.2 41.6 34.1 -12.0 108 140 A Q > - 0 0 134 -2,-0.3 4,-2.4 1,-0.1 3,-0.3 -0.246 36.5-113.8 -55.5 148.0 45.3 35.3 -11.7 109 141 A E H > S+ 0 0 41 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.886 115.0 54.6 -64.8 -36.6 47.2 33.1 -9.3 110 142 A E H > S+ 0 0 72 1,-0.2 4,-1.3 2,-0.2 152,-0.3 0.901 112.2 45.5 -62.4 -39.0 47.7 35.8 -6.7 111 143 A L H > S+ 0 0 2 -3,-0.3 4,-2.2 2,-0.2 -2,-0.2 0.913 111.3 51.4 -68.2 -42.7 44.0 36.4 -6.6 112 144 A A H X S+ 0 0 0 -4,-2.4 4,-3.0 1,-0.2 5,-0.2 0.874 108.6 53.0 -60.8 -38.4 43.1 32.6 -6.4 113 145 A R H X S+ 0 0 46 -4,-2.3 4,-2.1 2,-0.2 -1,-0.2 0.856 109.5 46.6 -68.4 -40.9 45.5 32.2 -3.5 114 146 A S H X S+ 0 0 1 -4,-1.3 4,-2.2 -5,-0.2 -1,-0.2 0.924 117.1 44.6 -65.1 -43.6 43.9 34.9 -1.4 115 147 A F H X S+ 0 0 0 -4,-2.2 4,-1.8 2,-0.2 -2,-0.2 0.914 115.0 46.4 -70.0 -42.5 40.5 33.6 -2.2 116 148 A F H X S+ 0 0 0 -4,-3.0 4,-3.0 2,-0.2 -1,-0.2 0.929 111.5 52.2 -68.0 -44.6 41.3 30.0 -1.6 117 149 A W H X S+ 0 0 65 -4,-2.1 4,-2.6 1,-0.2 -2,-0.2 0.951 108.8 49.8 -58.8 -48.7 43.1 30.8 1.6 118 150 A Q H X S+ 0 0 29 -4,-2.2 4,-1.7 1,-0.2 -1,-0.2 0.833 110.9 50.8 -61.5 -31.6 40.1 32.7 2.9 119 151 A V H X S+ 0 0 4 -4,-1.8 4,-2.5 2,-0.2 5,-0.3 0.952 107.4 52.8 -67.7 -50.0 37.9 29.8 2.0 120 152 A L H X S+ 0 0 0 -4,-3.0 4,-2.8 1,-0.2 -2,-0.2 0.938 108.6 50.6 -46.7 -50.5 40.2 27.4 3.9 121 153 A E H X S+ 0 0 81 -4,-2.6 4,-2.3 1,-0.2 -1,-0.2 0.870 111.5 47.4 -57.2 -40.7 39.9 29.7 6.9 122 154 A A H X S+ 0 0 4 -4,-1.7 4,-2.4 2,-0.2 -1,-0.2 0.839 112.4 48.7 -69.4 -38.4 36.0 29.7 6.8 123 155 A V H X S+ 0 0 4 -4,-2.5 4,-2.3 2,-0.2 -2,-0.2 0.877 110.4 52.4 -71.2 -35.9 35.9 25.9 6.3 124 156 A R H X S+ 0 0 111 -4,-2.8 4,-3.0 -5,-0.3 -2,-0.2 0.935 108.4 51.9 -61.9 -44.5 38.3 25.6 9.3 125 157 A H H X S+ 0 0 37 -4,-2.3 4,-1.3 1,-0.2 -2,-0.2 0.945 109.4 47.7 -55.5 -51.4 35.9 27.7 11.3 126 158 A C H <>S+ 0 0 1 -4,-2.4 5,-2.9 1,-0.2 3,-0.4 0.918 115.0 45.5 -58.3 -44.1 32.9 25.6 10.5 127 159 A H H ><5S+ 0 0 21 -4,-2.3 3,-1.7 1,-0.3 -1,-0.2 0.916 109.3 54.7 -65.4 -41.8 34.7 22.4 11.3 128 160 A N H 3<5S+ 0 0 141 -4,-3.0 -1,-0.3 1,-0.3 -2,-0.2 0.755 110.3 48.6 -61.3 -25.9 36.1 23.9 14.5 129 161 A C T 3<5S- 0 0 27 -4,-1.3 -1,-0.3 -3,-0.4 -2,-0.2 0.325 124.3-101.9 -96.3 3.3 32.4 24.7 15.4 130 162 A G T < 5S+ 0 0 22 -3,-1.7 31,-1.8 1,-0.3 2,-0.4 0.721 81.0 126.0 87.0 22.9 31.2 21.2 14.6 131 163 A V E < -I 160 0D 0 -5,-2.9 2,-0.5 29,-0.3 -1,-0.3 -0.945 42.0-164.2-121.3 131.5 29.6 22.0 11.2 132 164 A L E -I 159 0D 4 27,-3.3 27,-2.1 -2,-0.4 57,-0.0 -0.967 5.1-162.8-107.7 128.3 30.2 20.4 7.8 133 165 A H - 0 0 6 -2,-0.5 24,-0.3 25,-0.2 -1,-0.1 0.934 9.5-170.4 -76.0 -48.7 28.9 22.5 4.8 134 166 A R S S+ 0 0 22 54,-0.1 38,-0.2 24,-0.1 36,-0.1 0.555 71.1 64.9 66.7 16.2 28.9 19.7 2.2 135 167 A D + 0 0 19 36,-0.2 2,-0.4 5,-0.1 5,-0.1 -0.027 60.7 159.9-155.2 38.1 28.2 22.0 -0.7 136 168 A I + 0 0 5 39,-0.1 2,-0.3 3,-0.1 63,-0.1 -0.530 23.1 127.8 -65.8 123.8 31.3 24.2 -1.0 137 169 A K S > S- 0 0 22 -2,-0.4 3,-1.9 61,-0.1 -40,-0.1 -0.943 73.7 -86.8-170.8 166.4 31.4 25.7 -4.5 138 170 A D G > S+ 0 0 7 1,-0.3 3,-1.4 -2,-0.3 -40,-1.0 0.781 121.3 60.4 -61.2 -30.5 31.7 29.2 -6.1 139 171 A E G 3 S+ 0 0 86 1,-0.3 -1,-0.3 -42,-0.2 -3,-0.1 0.643 102.5 54.5 -67.9 -19.8 27.9 29.9 -6.0 140 172 A N G < S+ 0 0 6 -3,-1.9 13,-2.5 -5,-0.1 2,-0.4 0.123 94.5 82.7-104.6 22.3 28.1 29.5 -2.2 141 173 A I E < - H 0 152C 2 -3,-1.4 -44,-2.4 11,-0.2 2,-0.4 -0.987 61.3-158.8-127.5 126.6 30.9 32.1 -1.8 142 174 A L E -GH 96 151C 34 9,-3.0 9,-2.2 -2,-0.4 2,-0.5 -0.848 6.3-148.4-101.0 142.0 30.2 35.9 -1.6 143 175 A I E -GH 95 150C 0 -48,-2.2 -48,-1.6 -2,-0.4 2,-1.0 -0.949 7.0-148.6-103.7 127.7 32.9 38.5 -2.3 144 176 A D E >> -GH 94 149C 16 5,-2.1 4,-1.8 -2,-0.5 5,-0.7 -0.854 17.9-156.0 -86.1 100.6 32.7 41.9 -0.5 145 177 A L T 45S+ 0 0 40 -52,-1.5 -51,-0.1 -2,-1.0 -1,-0.1 0.567 83.7 49.1 -64.4 -11.5 34.2 43.9 -3.3 146 178 A N T 45S+ 0 0 84 -53,-0.5 -1,-0.2 3,-0.1 126,-0.1 0.875 121.7 28.1 -89.8 -46.8 35.5 46.7 -1.1 147 179 A R T 45S- 0 0 134 -3,-0.2 121,-0.2 2,-0.1 -2,-0.2 0.470 97.2-129.2 -93.4 -5.4 37.2 44.8 1.7 148 180 A G T <5 + 0 0 0 -4,-1.8 2,-0.4 1,-0.2 -3,-0.2 0.743 57.1 147.3 59.8 26.5 38.2 41.7 -0.4 149 181 A E E < - H 0 144C 66 -5,-0.7 -5,-2.1 116,-0.0 2,-0.2 -0.813 38.7-145.9 -95.7 128.5 36.7 39.4 2.2 150 182 A L E - H 0 143C 5 -2,-0.4 2,-0.4 -7,-0.2 -7,-0.2 -0.633 14.4-165.0 -88.1 152.8 35.0 36.1 1.1 151 183 A K E - H 0 142C 31 -9,-2.2 -9,-3.0 -2,-0.2 2,-0.3 -0.995 15.4-127.9-146.2 135.3 32.0 34.7 3.0 152 184 A L E +fH 71 141C 5 -82,-2.2 -80,-2.0 -2,-0.4 2,-0.3 -0.588 31.5 179.6 -89.2 136.4 30.4 31.3 3.0 153 185 A I + 0 0 27 -13,-2.5 -80,-0.0 -2,-0.3 -13,-0.0 -0.810 39.9 41.2-131.9 168.2 26.7 30.8 2.4 154 186 A D + 0 0 21 -2,-0.3 3,-0.5 1,-0.1 -1,-0.2 0.946 41.1 177.6 61.5 68.4 23.9 28.3 2.1 155 187 A F > + 0 0 1 1,-0.2 3,-1.9 -3,-0.1 -1,-0.1 0.176 44.8 117.5 -79.6 15.2 24.3 25.6 4.7 156 188 A G T 3 S+ 0 0 48 1,-0.3 -1,-0.2 -21,-0.1 -112,-0.1 0.622 79.7 42.3 -64.8 -12.9 21.1 23.8 3.7 157 189 A S T 3 S+ 0 0 18 -3,-0.5 13,-0.4 -24,-0.3 -1,-0.3 0.219 96.6 112.3-110.0 11.4 22.9 20.6 2.7 158 190 A G < - 0 0 3 -3,-1.9 2,-0.3 11,-0.1 -25,-0.2 -0.185 45.2-166.0 -81.2 171.0 25.2 20.7 5.7 159 191 A A E -I 132 0D 14 -27,-2.1 -27,-3.3 -99,-0.0 2,-0.2 -0.937 36.1 -83.8-143.7 165.7 25.5 18.3 8.7 160 192 A L E -I 131 0D 81 -2,-0.3 -29,-0.3 -29,-0.2 2,-0.1 -0.571 58.0-103.6 -62.4 139.0 27.0 18.3 12.1 161 193 A L + 0 0 34 -31,-1.8 2,-0.3 -2,-0.2 -1,-0.1 -0.410 50.4 170.2 -67.7 137.2 30.7 17.1 11.8 162 194 A K - 0 0 82 2,-0.2 26,-0.5 -2,-0.1 4,-0.1 -0.963 39.2-133.3-149.6 160.6 31.1 13.5 12.9 163 195 A D S S+ 0 0 125 -2,-0.3 3,-0.1 24,-0.1 2,-0.1 0.566 82.2 79.2 -99.0 -15.4 34.0 11.1 12.6 164 196 A T S S- 0 0 94 1,-0.1 24,-0.4 23,-0.0 -2,-0.2 -0.168 94.8 -66.0 -83.9-177.4 32.0 8.1 11.3 165 197 A V - 0 0 30 22,-0.1 2,-0.5 -2,-0.1 22,-0.2 -0.444 37.1-140.6 -87.9 143.8 30.8 7.5 7.8 166 198 A Y B +J 186 0E 3 20,-3.4 20,-1.8 -2,-0.1 -1,-0.0 -0.902 20.1 175.1 -98.6 131.9 28.2 9.7 5.9 167 199 A T + 0 0 88 -2,-0.5 2,-0.4 18,-0.2 -1,-0.1 0.130 60.6 73.3-118.3 17.9 25.8 7.8 3.7 168 200 A D + 0 0 70 18,-0.1 2,-0.4 2,-0.0 18,-0.0 -0.994 52.2 171.1-136.1 131.5 23.7 10.8 2.8 169 201 A F + 0 0 43 -2,-0.4 -11,-0.1 1,-0.1 -35,-0.0 -0.987 18.2 162.3-143.2 136.4 24.5 13.6 0.4 170 202 A D + 0 0 109 -2,-0.4 3,-0.1 -13,-0.4 -12,-0.1 -0.070 49.3 107.2-135.7 31.6 22.4 16.4 -1.1 171 203 A G S S- 0 0 22 1,-0.2 2,-0.4 -14,-0.1 -36,-0.2 0.170 84.4 -55.0 -87.7-149.2 25.2 18.8 -2.3 172 204 A T > - 0 0 31 -38,-0.2 3,-1.0 1,-0.1 -1,-0.2 -0.834 44.7-143.5 -95.9 132.2 26.3 19.5 -5.9 173 205 A R G > S+ 0 0 106 -2,-0.4 3,-2.2 1,-0.3 -1,-0.1 0.885 95.3 57.0 -65.7 -39.1 27.2 16.3 -7.8 174 206 A V G 3 S+ 0 0 26 1,-0.3 36,-0.3 37,-0.1 -1,-0.3 0.586 109.7 47.7 -76.8 -11.6 30.1 17.7 -9.8 175 207 A Y G < S+ 0 0 13 -3,-1.0 -1,-0.3 33,-0.1 -2,-0.2 0.220 93.4 105.6-101.1 7.4 31.8 18.8 -6.5 176 208 A S S < S- 0 0 0 -3,-2.2 16,-0.0 1,-0.1 -3,-0.0 -0.657 72.8-110.5 -98.2 148.1 31.2 15.4 -4.9 177 209 A P >> - 0 0 4 0, 0.0 4,-1.7 0, 0.0 3,-1.1 -0.217 21.9-110.7 -82.0 163.4 34.0 12.9 -4.5 178 210 A P H 3> S+ 0 0 4 0, 0.0 4,-3.1 0, 0.0 5,-0.3 0.872 114.3 60.6 -61.1 -36.0 34.5 9.6 -6.2 179 211 A E H 3>>S+ 0 0 17 1,-0.2 4,-1.5 2,-0.2 6,-1.2 0.767 106.3 47.6 -64.7 -23.9 33.8 7.5 -3.1 180 212 A W H <>5S+ 0 0 24 -3,-1.1 4,-1.5 4,-0.2 -1,-0.2 0.926 112.2 49.2 -76.5 -41.3 30.3 9.0 -3.0 181 213 A I H <5S+ 0 0 17 -4,-1.7 -2,-0.2 1,-0.2 -1,-0.1 0.927 123.0 31.5 -64.2 -46.0 29.7 8.4 -6.6 182 214 A R H <5S+ 0 0 138 -4,-3.1 -1,-0.2 -5,-0.1 -3,-0.2 0.795 138.8 11.5 -81.4 -36.2 30.8 4.7 -6.4 183 215 A Y H <5S- 0 0 138 -4,-1.5 -3,-0.2 -5,-0.3 -2,-0.2 0.522 84.9-123.4-127.3 -13.9 29.8 3.7 -2.9 184 216 A H S < - 0 0 80 -2,-0.3 4,-1.8 -22,-0.2 5,-0.2 -0.906 30.2-118.0-120.2 152.4 33.9 11.1 5.5 188 220 A G H > S+ 0 0 1 -26,-0.5 4,-1.7 -24,-0.4 5,-0.1 0.874 104.2 40.9 -62.7 -49.3 33.5 14.8 6.2 189 221 A R H > S+ 0 0 104 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.950 115.8 48.5 -69.6 -49.6 37.0 16.2 6.0 190 222 A S H > S+ 0 0 23 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.833 112.7 48.5 -62.5 -33.3 38.2 14.2 3.0 191 223 A A H X S+ 0 0 14 -4,-1.8 4,-1.9 2,-0.2 -1,-0.2 0.877 110.8 51.9 -72.6 -35.8 35.0 15.1 1.0 192 224 A A H X S+ 0 0 8 -4,-1.7 4,-1.7 -5,-0.2 -2,-0.2 0.925 108.0 51.0 -67.2 -40.8 35.5 18.7 1.9 193 225 A V H X S+ 0 0 4 -4,-2.6 4,-2.4 1,-0.2 3,-0.4 0.961 108.4 53.2 -61.4 -46.1 39.2 18.6 0.7 194 226 A W H X S+ 0 0 0 -4,-1.9 4,-1.5 1,-0.3 -1,-0.2 0.897 110.3 45.8 -51.3 -48.4 38.0 17.1 -2.7 195 227 A S H X S+ 0 0 10 -4,-1.9 4,-2.0 2,-0.2 -1,-0.3 0.752 107.6 57.9 -70.5 -24.0 35.5 19.9 -3.2 196 228 A L H X S+ 0 0 0 -4,-1.7 4,-2.8 -3,-0.4 -2,-0.2 0.911 105.3 51.7 -72.8 -35.3 38.1 22.4 -2.3 197 229 A G H X S+ 0 0 0 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.853 108.9 49.0 -60.7 -39.2 40.2 20.9 -5.2 198 230 A I H X S+ 0 0 0 -4,-1.5 4,-2.8 2,-0.2 -1,-0.2 0.904 113.9 48.1 -67.6 -39.8 37.3 21.3 -7.6 199 231 A L H X S+ 0 0 0 -4,-2.0 4,-2.3 2,-0.2 -2,-0.2 0.902 109.5 50.8 -66.3 -43.8 37.0 24.9 -6.3 200 232 A L H X S+ 0 0 0 -4,-2.8 4,-2.2 2,-0.2 5,-0.3 0.970 113.2 45.2 -64.4 -45.6 40.7 25.6 -6.7 201 233 A Y H X>S+ 0 0 2 -4,-2.3 4,-2.9 1,-0.2 5,-0.6 0.972 110.2 56.7 -56.1 -50.8 40.7 24.3 -10.3 202 234 A D H X5S+ 0 0 3 -4,-2.8 4,-1.8 1,-0.2 -1,-0.2 0.866 109.6 45.0 -46.7 -44.1 37.5 26.3 -10.9 203 235 A M H <5S+ 0 0 0 -4,-2.3 -96,-3.1 1,-0.2 -1,-0.2 0.931 119.1 38.5 -70.3 -48.9 39.3 29.5 -9.8 204 236 A V H <5S+ 0 0 6 -4,-2.2 -2,-0.2 -98,-0.2 -1,-0.2 0.710 127.1 34.0 -75.5 -23.1 42.5 29.0 -11.8 205 237 A C H <5S- 0 0 6 -4,-2.9 -99,-0.4 -5,-0.3 -3,-0.2 0.698 103.2-119.0-105.6 -23.0 41.0 27.6 -14.9 206 238 A G S <> S- 0 0 114 1,-0.1 4,-1.6 -38,-0.1 3,-0.7 -0.821 78.8-123.8-117.9 151.0 30.4 13.5 -15.7 213 245 A D H 3> S+ 0 0 47 -2,-0.3 4,-2.7 1,-0.2 5,-0.2 0.893 111.7 57.2 -54.4 -44.7 30.5 10.7 -13.2 214 246 A E H 3> S+ 0 0 128 1,-0.2 4,-1.3 2,-0.2 -1,-0.2 0.822 106.2 50.4 -57.1 -34.4 33.0 8.7 -15.3 215 247 A E H <> S+ 0 0 78 -3,-0.7 4,-1.7 2,-0.2 5,-0.4 0.865 110.5 48.7 -74.1 -41.0 35.5 11.7 -15.1 216 248 A I H < S+ 0 0 1 -4,-1.6 3,-0.4 2,-0.2 -2,-0.2 0.964 110.3 50.6 -61.9 -56.4 35.2 12.0 -11.3 217 249 A I H < S+ 0 0 56 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.853 112.9 47.4 -48.4 -39.8 35.8 8.2 -10.8 218 250 A R H < S- 0 0 162 -4,-1.3 -1,-0.2 -5,-0.2 -2,-0.2 0.806 87.5-162.3 -80.2 -31.3 38.9 8.5 -13.0 219 251 A G < + 0 0 17 -4,-1.7 2,-0.6 -3,-0.4 -3,-0.1 0.591 36.2 141.5 65.5 14.3 40.2 11.6 -11.2 220 252 A Q - 0 0 130 -5,-0.4 2,-0.5 2,-0.0 -1,-0.2 -0.789 37.8-155.3 -89.2 118.7 42.6 12.5 -14.1 221 253 A V - 0 0 12 -2,-0.6 2,-0.4 -3,-0.1 -11,-0.1 -0.864 5.0-158.1-103.2 127.9 42.6 16.4 -14.4 222 254 A F - 0 0 158 -2,-0.5 2,-0.5 -13,-0.2 -2,-0.0 -0.830 14.5-136.5 -97.2 139.7 43.5 18.1 -17.6 223 255 A F + 0 0 26 -2,-0.4 4,-0.0 1,-0.1 3,-0.0 -0.888 21.3 179.3 -99.2 127.7 44.6 21.7 -17.4 224 256 A R + 0 0 119 -2,-0.5 2,-0.3 2,-0.1 -1,-0.1 0.584 68.6 46.1-105.8 -18.4 43.2 24.0 -20.0 225 257 A Q S S- 0 0 101 0, 0.0 2,-0.6 0, 0.0 -19,-0.0 -0.863 101.9 -86.7-116.8 163.1 44.9 27.2 -18.9 226 258 A R + 0 0 205 -2,-0.3 2,-0.3 -21,-0.0 -2,-0.1 -0.589 56.5 170.9 -72.2 112.7 48.5 27.9 -18.0 227 259 A V - 0 0 4 -2,-0.6 -4,-0.0 -4,-0.0 -22,-0.0 -0.954 36.0-102.4-124.0 141.6 48.6 27.0 -14.3 228 260 A S > - 0 0 18 -2,-0.3 4,-2.5 1,-0.1 5,-0.2 -0.226 26.4-118.0 -64.2 154.1 51.8 26.8 -12.2 229 261 A S H > S+ 0 0 94 1,-0.2 4,-1.6 2,-0.2 -1,-0.1 0.853 114.7 52.0 -61.9 -36.2 53.3 23.5 -11.3 230 262 A E H > S+ 0 0 100 2,-0.2 4,-2.0 1,-0.2 27,-0.2 0.897 111.3 46.8 -66.4 -37.9 52.9 24.1 -7.6 231 263 A C H > S+ 0 0 0 1,-0.2 4,-2.1 2,-0.2 -2,-0.2 0.902 112.2 50.0 -71.4 -41.6 49.2 25.0 -8.1 232 264 A Q H X S+ 0 0 47 -4,-2.5 4,-2.1 2,-0.2 -1,-0.2 0.835 109.2 53.8 -60.1 -33.1 48.7 21.9 -10.3 233 265 A H H X S+ 0 0 106 -4,-1.6 4,-1.3 -5,-0.2 -2,-0.2 0.941 110.3 44.8 -72.1 -43.0 50.4 19.8 -7.6 234 266 A L H X S+ 0 0 0 -4,-2.0 4,-2.0 2,-0.2 -2,-0.2 0.856 112.0 53.2 -67.3 -37.4 48.0 21.0 -4.8 235 267 A I H X S+ 0 0 0 -4,-2.1 4,-1.7 1,-0.2 -1,-0.2 0.955 110.5 46.3 -65.5 -47.5 45.0 20.6 -7.0 236 268 A R H < S+ 0 0 108 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.724 109.5 55.3 -69.6 -23.9 45.9 17.0 -7.8 237 269 A W H >< S+ 0 0 74 -4,-1.3 3,-1.1 2,-0.2 -1,-0.2 0.879 109.2 45.5 -74.0 -41.5 46.6 16.3 -4.2 238 270 A C H 3< S+ 0 0 0 -4,-2.0 -41,-0.2 1,-0.2 -2,-0.2 0.800 113.6 52.9 -65.2 -31.8 43.1 17.5 -3.1 239 271 A L T 3< S+ 0 0 4 -4,-1.7 -1,-0.2 -5,-0.2 -2,-0.2 0.078 77.2 141.1 -92.2 20.7 41.7 15.5 -6.0 240 272 A A < - 0 0 20 -3,-1.1 6,-0.1 1,-0.1 -21,-0.1 -0.420 55.8-131.2 -62.7 140.0 43.4 12.2 -5.0 241 273 A L S S+ 0 0 80 -23,-0.1 -62,-0.2 4,-0.1 -1,-0.1 0.833 92.0 67.7 -60.4 -35.9 41.1 9.2 -5.6 242 274 A R S > S- 0 0 160 1,-0.2 3,-1.9 -64,-0.1 4,-0.4 -0.779 77.7-144.4 -91.1 123.5 41.7 7.8 -2.1 243 275 A P G > S+ 0 0 45 0, 0.0 3,-2.3 0, 0.0 -1,-0.2 0.908 101.0 56.5 -48.5 -44.1 40.4 9.9 0.7 244 276 A S G 3 S+ 0 0 94 1,-0.3 -3,-0.0 -3,-0.1 -2,-0.0 0.705 100.2 59.5 -67.7 -17.1 43.3 9.0 2.9 245 277 A D G < S+ 0 0 77 -3,-1.9 -1,-0.3 2,-0.1 -5,-0.1 0.449 86.7 98.8 -86.0 2.1 45.7 10.3 0.2 246 278 A R S < S- 0 0 15 -3,-2.3 -8,-0.2 -4,-0.4 2,-0.2 -0.473 80.0-104.1 -87.7 157.0 44.1 13.8 0.4 247 279 A P - 0 0 5 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.507 24.6-119.5 -79.2 154.0 45.7 16.5 2.4 248 280 A T > - 0 0 73 -2,-0.2 4,-1.9 1,-0.1 5,-0.1 -0.360 36.4-102.9 -70.6 164.1 44.6 17.8 5.8 249 281 A F H > S+ 0 0 30 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.859 124.9 54.2 -57.2 -38.4 43.7 21.5 6.0 250 282 A E H > S+ 0 0 135 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.868 106.4 50.5 -65.0 -38.5 47.0 22.1 7.6 251 283 A E H 4 S+ 0 0 82 2,-0.2 -2,-0.2 1,-0.2 -1,-0.2 0.832 108.8 52.7 -70.3 -30.9 48.9 20.5 4.8 252 284 A I H >< S+ 0 0 0 -4,-1.9 3,-2.0 2,-0.2 6,-0.3 0.983 111.9 44.0 -64.6 -55.0 47.0 22.6 2.3 253 285 A Q H 3< S+ 0 0 13 -4,-2.1 -2,-0.2 1,-0.3 -1,-0.2 0.710 114.7 51.0 -69.0 -20.4 47.9 25.9 4.1 254 286 A N T 3< S+ 0 0 106 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.359 83.6 116.1 -91.9 6.1 51.5 24.7 4.5 255 287 A H S X S- 0 0 9 -3,-2.0 3,-1.5 1,-0.1 4,-0.2 -0.517 78.1-119.5 -70.7 143.5 51.8 23.8 0.7 256 288 A P G > S+ 0 0 72 0, 0.0 3,-1.2 0, 0.0 -1,-0.1 0.795 111.7 61.1 -57.6 -27.5 54.4 26.0 -1.0 257 289 A W G 3 S+ 0 0 2 -27,-0.2 -26,-0.1 1,-0.2 -4,-0.1 0.833 99.3 56.4 -67.5 -28.1 51.7 27.4 -3.4 258 290 A M G X S+ 0 0 2 -3,-1.5 3,-0.6 -6,-0.3 -1,-0.2 0.342 82.1 114.9 -86.5 7.8 49.8 28.9 -0.4 259 291 A Q T < S+ 0 0 92 -3,-1.2 -5,-0.0 -4,-0.2 -146,-0.0 -0.452 71.8 20.3 -81.0 150.7 52.8 31.0 1.0 260 292 A D T 3 S- 0 0 149 1,-0.2 -1,-0.2 -2,-0.1 -147,-0.0 0.784 79.1-172.5 63.0 32.6 52.7 34.8 1.1 261 293 A V < - 0 0 38 -3,-0.6 -1,-0.2 -148,-0.1 2,-0.2 -0.247 24.7-116.1 -49.7 138.6 48.9 35.2 0.8 262 294 A L - 0 0 22 -152,-0.3 -1,-0.1 1,-0.1 -2,-0.0 -0.459 28.2-111.6 -65.2 150.1 47.8 38.7 0.3 263 295 A L >> - 0 0 114 -2,-0.2 4,-2.5 1,-0.1 3,-0.6 -0.636 35.3-105.5 -82.3 150.9 45.7 40.2 3.1 264 296 A P H 3> S+ 0 0 39 0, 0.0 4,-2.1 0, 0.0 5,-0.2 0.823 117.9 50.3 -47.7 -44.8 42.0 40.9 2.0 265 297 A Q H 3> S+ 0 0 75 2,-0.2 4,-2.3 1,-0.2 5,-0.1 0.881 111.9 46.3 -65.1 -41.3 42.4 44.7 1.7 266 298 A E H <> S+ 0 0 80 -3,-0.6 4,-3.0 1,-0.2 5,-0.3 0.900 111.3 55.6 -64.3 -41.5 45.5 44.4 -0.5 267 299 A T H X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 5,-0.3 0.900 110.3 43.4 -57.4 -41.0 43.7 41.8 -2.5 268 300 A A H X>S+ 0 0 0 -4,-2.1 5,-2.3 -121,-0.2 4,-1.8 0.871 113.9 50.6 -78.8 -33.4 40.8 44.2 -3.1 269 301 A E H <5S+ 0 0 121 -4,-2.3 4,-0.2 3,-0.2 -2,-0.2 0.957 119.5 36.3 -62.8 -49.2 43.1 47.1 -3.9 270 302 A I H <5S+ 0 0 97 -4,-3.0 -2,-0.2 -5,-0.1 -3,-0.2 0.931 136.3 15.7 -70.9 -46.4 45.1 45.1 -6.4 271 303 A H H <5S+ 0 0 17 -4,-2.5 -3,-0.2 -5,-0.3 -2,-0.2 0.484 129.1 34.2-111.9 -7.6 42.4 43.0 -8.0 272 304 A L T <5S+ 0 0 22 -4,-1.8 -3,-0.2 -5,-0.3 -4,-0.1 0.704 83.3 96.1-126.5 -27.8 39.0 44.4 -7.1 273 305 A H < 0 0 80 -5,-2.3 -127,-0.1 -4,-0.2 -4,-0.0 -0.393 360.0 360.0 -78.3 147.5 38.8 48.2 -6.9 274 306 A S 0 0 177 -2,-0.1 -5,-0.0 0, 0.0 -1,-0.0 -0.306 360.0 360.0 66.8 360.0 37.7 50.7 -9.6