==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=21-AUG-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR 27-MAR-10 3MC5 . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.KOCH,A.HEINE,G.KLEBE . 316 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13513.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 201 63.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 11 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 44 13.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 26.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 2 1 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A M 0 0 111 0, 0.0 254,-0.0 0, 0.0 2,-0.0 0.000 360.0 360.0 360.0 136.9 8.3 38.4 -22.7 2 1 A A - 0 0 75 1,-0.1 13,-0.1 2,-0.0 0, 0.0 -0.239 360.0-146.7 -53.2 127.3 6.7 37.9 -19.3 3 2 A S S S+ 0 0 73 11,-0.1 12,-2.6 12,-0.1 13,-0.4 0.630 75.5 43.1 -76.0 -17.2 9.1 36.6 -16.7 4 3 A R E -A 14 0A 119 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.934 65.2-145.2-132.4 156.7 6.6 34.5 -14.7 5 4 A I E -A 13 0A 36 8,-2.3 8,-2.9 -2,-0.3 2,-0.3 -0.938 27.6-113.1-118.7 139.7 3.8 32.0 -15.5 6 5 A L E -A 12 0A 111 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.577 28.6-154.9 -79.0 128.3 0.6 31.6 -13.4 7 6 A L > - 0 0 7 4,-3.1 3,-2.0 -2,-0.3 198,-0.1 -0.540 31.7-103.7 -95.9 170.7 0.1 28.3 -11.5 8 7 A N T 3 S+ 0 0 78 1,-0.3 171,-0.1 196,-0.2 -2,-0.0 0.564 118.7 62.0 -77.2 -7.2 -3.2 26.7 -10.4 9 8 A N T 3 S- 0 0 58 2,-0.2 -1,-0.3 169,-0.0 3,-0.1 0.334 120.4-105.8 -94.4 6.5 -2.6 27.9 -6.8 10 9 A G S < S+ 0 0 50 -3,-2.0 2,-0.2 1,-0.3 -2,-0.1 0.385 83.0 122.9 86.5 -7.8 -2.6 31.5 -7.9 11 10 A A - 0 0 14 144,-0.1 -4,-3.1 95,-0.1 2,-0.5 -0.521 58.8-127.8 -85.0 154.4 1.2 31.9 -7.5 12 11 A K E -A 6 0A 105 -6,-0.2 -6,-0.2 -2,-0.2 -1,-0.0 -0.910 17.3-155.0-109.8 133.9 3.5 33.0 -10.3 13 12 A M E -A 5 0A 1 -8,-2.9 -8,-2.3 -2,-0.5 2,-0.1 -0.908 21.9-117.1-110.2 123.3 6.6 30.9 -11.2 14 13 A P E -A 4 0A 13 0, 0.0 -10,-0.3 0, 0.0 -11,-0.1 -0.396 18.0-141.3 -60.3 135.1 9.7 32.4 -12.9 15 14 A I S S+ 0 0 11 -12,-2.6 245,-2.7 244,-0.1 2,-0.5 0.650 86.8 54.1 -76.9 -13.1 10.1 30.9 -16.3 16 15 A L B +b 260 0B 4 -13,-0.4 25,-0.5 243,-0.2 26,-0.5 -0.987 69.5 164.4-120.1 124.3 13.9 30.8 -16.0 17 16 A G - 0 0 0 243,-2.5 2,-0.6 -2,-0.5 26,-0.2 -0.857 37.7-103.7-130.8 170.3 15.5 29.1 -13.0 18 17 A L E -c 43 0B 1 24,-2.3 26,-2.8 -2,-0.3 245,-0.2 -0.847 28.7-142.9 -95.4 122.7 18.9 27.7 -12.0 19 18 A G E -cd 44 263B 5 243,-2.0 245,-0.6 -2,-0.6 26,-0.1 -0.496 14.1-174.1 -75.8 150.0 19.5 24.0 -12.1 20 19 A T > + 0 0 0 24,-0.6 3,-1.7 -2,-0.2 2,-0.4 0.344 37.7 124.1-131.2 4.5 21.6 22.4 -9.4 21 20 A W T 3 S+ 0 0 62 1,-0.3 -2,-0.1 23,-0.1 28,-0.1 -0.604 88.6 11.4 -70.2 126.3 22.1 18.8 -10.3 22 21 A K T 3 S+ 0 0 48 -2,-0.4 -1,-0.3 1,-0.3 243,-0.1 0.514 88.9 133.1 78.4 16.5 25.9 18.1 -10.4 23 22 A S < - 0 0 2 -3,-1.7 -1,-0.3 241,-0.1 5,-0.2 -0.817 59.3-131.6 -89.8 104.8 26.7 21.4 -8.8 24 23 A P >> - 0 0 49 0, 0.0 4,-2.6 0, 0.0 3,-2.6 -0.240 10.2-120.3 -65.8 149.6 29.3 20.2 -6.2 25 24 A P H 3> S+ 0 0 56 0, 0.0 4,-0.6 0, 0.0 26,-0.0 0.858 113.9 61.0 -56.9 -32.4 28.8 21.4 -2.7 26 25 A G H 34 S+ 0 0 77 1,-0.2 4,-0.0 2,-0.1 25,-0.0 0.577 120.5 24.3 -71.0 -8.0 32.2 23.0 -2.8 27 26 A Q H <> S+ 0 0 109 -3,-2.6 4,-1.4 2,-0.1 -1,-0.2 0.498 101.9 79.5-126.1 -17.3 31.1 25.2 -5.7 28 27 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 1,-0.2 5,-0.3 0.796 83.6 63.2 -72.4 -27.0 27.2 25.6 -5.6 29 28 A T H X S+ 0 0 32 -4,-0.6 4,-2.3 1,-0.2 -1,-0.2 0.960 108.1 43.5 -60.5 -45.1 27.0 28.2 -2.9 30 29 A E H > S+ 0 0 95 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.898 111.2 55.8 -66.7 -37.4 28.9 30.7 -5.1 31 30 A A H X S+ 0 0 0 -4,-1.4 4,-2.6 1,-0.2 -1,-0.2 0.913 110.4 44.1 -59.6 -48.0 26.8 29.7 -8.1 32 31 A V H X S+ 0 0 0 -4,-2.5 4,-2.7 2,-0.2 -1,-0.2 0.890 111.7 53.2 -67.6 -38.2 23.6 30.5 -6.3 33 32 A K H X S+ 0 0 40 -4,-2.3 4,-2.5 -5,-0.3 -2,-0.2 0.946 112.8 44.1 -57.5 -49.4 24.9 33.7 -4.9 34 33 A V H X S+ 0 0 23 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.927 111.5 53.9 -61.6 -47.0 25.9 34.9 -8.4 35 34 A A H X>S+ 0 0 0 -4,-2.6 5,-2.3 2,-0.2 4,-0.8 0.943 109.9 47.2 -58.6 -46.9 22.6 33.7 -9.9 36 35 A I H ><5S+ 0 0 0 -4,-2.7 3,-1.1 1,-0.2 -1,-0.2 0.951 110.1 53.7 -60.9 -41.6 20.7 35.7 -7.3 37 36 A D H 3<5S+ 0 0 91 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.855 110.2 46.6 -58.9 -35.4 22.9 38.8 -8.0 38 37 A V H 3<5S- 0 0 61 -4,-2.0 -1,-0.3 -3,-0.2 -2,-0.2 0.465 130.8 -86.6 -96.0 0.3 22.2 38.6 -11.8 39 38 A G T <<5S+ 0 0 23 -3,-1.1 -3,-0.2 -4,-0.8 -2,-0.1 0.341 74.2 143.9 124.3 -3.5 18.5 38.2 -11.4 40 39 A Y < + 0 0 0 -5,-2.3 -1,-0.3 -6,-0.2 -23,-0.1 -0.411 12.0 168.4 -64.5 135.8 17.6 34.5 -11.0 41 40 A R + 0 0 70 -25,-0.5 33,-3.2 1,-0.2 2,-0.5 0.386 57.4 71.0-123.5 -8.5 14.7 34.1 -8.6 42 41 A H E - e 0 74B 0 -26,-0.5 -24,-2.3 31,-0.2 2,-0.4 -0.974 57.8-174.8-114.9 129.2 13.9 30.4 -9.2 43 42 A I E -ce 18 75B 0 31,-1.8 33,-2.4 -2,-0.5 2,-0.6 -0.995 14.7-147.8-126.1 127.7 16.2 27.6 -8.0 44 43 A D E +ce 19 76B 3 -26,-2.8 -24,-0.6 -2,-0.4 2,-0.2 -0.901 30.7 166.1 -99.3 120.8 15.6 23.9 -8.9 45 44 A C - 0 0 0 31,-2.4 2,-0.3 -2,-0.6 3,-0.1 -0.701 18.6-171.0-122.6 172.5 16.8 21.6 -6.1 46 45 A A > - 0 0 0 -2,-0.2 3,-1.2 31,-0.2 5,-0.5 -0.919 32.1-127.3-164.3 146.8 16.5 18.0 -5.0 47 46 A H G > S+ 0 0 33 31,-1.1 3,-1.9 -2,-0.3 5,-0.2 0.906 110.7 58.7 -55.8 -42.5 17.4 16.0 -1.9 48 47 A V G 3 S+ 0 0 22 1,-0.3 -1,-0.3 30,-0.3 74,-0.1 0.725 89.4 71.9 -66.3 -18.3 19.2 13.4 -4.2 49 48 A Y G < S- 0 0 39 -3,-1.2 -1,-0.3 1,-0.1 -27,-0.2 0.687 93.8-144.4 -73.7 -12.3 21.5 16.2 -5.5 50 49 A Q S < S+ 0 0 144 -3,-1.9 -3,-0.1 -4,-0.4 -2,-0.1 0.734 76.5 88.7 63.0 29.8 23.2 16.1 -2.1 51 50 A N > + 0 0 1 -5,-0.5 4,-2.0 2,-0.1 5,-0.2 0.188 41.4 113.0-139.5 9.7 23.9 19.9 -2.1 52 51 A E H > S+ 0 0 3 1,-0.2 4,-2.5 -6,-0.2 5,-0.1 0.847 76.8 57.4 -61.7 -33.8 20.7 21.4 -0.5 53 52 A N H > S+ 0 0 61 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.936 109.3 45.3 -60.6 -44.3 22.6 22.6 2.5 54 53 A E H > S+ 0 0 60 2,-0.2 4,-1.3 1,-0.2 -2,-0.2 0.825 111.9 51.1 -73.5 -31.2 25.0 24.6 0.3 55 54 A V H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -1,-0.2 0.920 109.9 51.5 -61.6 -46.4 22.2 26.0 -1.7 56 55 A G H X S+ 0 0 0 -4,-2.5 4,-2.8 1,-0.2 -2,-0.2 0.872 104.2 57.0 -61.1 -38.2 20.5 27.0 1.5 57 56 A V H X S+ 0 0 65 -4,-2.0 4,-2.1 1,-0.2 -1,-0.2 0.913 108.1 47.4 -56.9 -44.7 23.7 28.8 2.7 58 57 A A H X S+ 0 0 0 -4,-1.3 4,-2.2 2,-0.2 -2,-0.2 0.918 112.2 48.9 -66.3 -46.0 23.7 31.0 -0.4 59 58 A I H X S+ 0 0 2 -4,-2.2 4,-2.4 1,-0.2 5,-0.3 0.950 111.1 50.5 -59.3 -47.6 20.0 31.8 -0.0 60 59 A Q H X S+ 0 0 109 -4,-2.8 4,-2.8 1,-0.2 -1,-0.2 0.915 109.9 50.4 -58.3 -42.6 20.4 32.7 3.6 61 60 A E H X S+ 0 0 66 -4,-2.1 4,-2.4 1,-0.2 -1,-0.2 0.935 110.0 48.2 -62.4 -43.9 23.3 35.0 2.9 62 61 A K H <>S+ 0 0 12 -4,-2.2 5,-2.1 1,-0.2 6,-0.9 0.834 111.4 51.9 -70.0 -31.8 21.5 36.9 0.2 63 62 A L H ><5S+ 0 0 57 -4,-2.4 3,-1.4 -5,-0.2 -1,-0.2 0.934 111.8 45.5 -65.9 -45.0 18.5 37.3 2.4 64 63 A R H 3<5S+ 0 0 81 -4,-2.8 -2,-0.2 1,-0.3 -1,-0.2 0.882 107.9 57.6 -67.4 -29.8 20.7 38.6 5.2 65 64 A E T 3<5S- 0 0 93 -4,-2.4 -1,-0.3 -5,-0.2 -2,-0.2 0.515 112.4-119.8 -72.9 -10.1 22.5 40.9 2.8 66 65 A Q T < 5S+ 0 0 180 -3,-1.4 -3,-0.2 -4,-0.3 -2,-0.1 0.756 77.6 125.8 73.7 25.5 19.2 42.5 1.8 67 66 A V S > - 0 0 121 -2,-0.3 3,-1.6 -3,-0.1 4,-0.5 -0.818 31.4-113.1-108.4 153.6 13.3 38.9 0.2 70 69 A R G >4 S+ 0 0 36 -2,-0.3 3,-1.7 1,-0.3 -1,-0.1 0.863 114.1 62.0 -57.3 -38.4 11.9 35.3 0.6 71 70 A E G 34 S+ 0 0 70 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.754 99.7 55.9 -60.7 -22.3 8.7 36.2 -1.1 72 71 A E G <4 S+ 0 0 82 -3,-1.6 -1,-0.3 2,-0.0 2,-0.3 0.606 94.6 84.3 -87.1 -13.3 10.6 37.0 -4.4 73 72 A L << - 0 0 3 -3,-1.7 2,-0.5 -4,-0.5 -31,-0.2 -0.643 61.5-156.9 -92.1 151.0 12.2 33.6 -4.5 74 73 A F E -e 42 0B 8 -33,-3.2 -31,-1.8 -2,-0.3 2,-0.5 -0.921 17.0-172.6-127.2 97.5 10.7 30.4 -6.0 75 74 A I E -e 43 0B 0 -2,-0.5 31,-1.6 -33,-0.2 32,-1.4 -0.869 1.0-170.6-103.2 126.2 12.4 27.4 -4.5 76 75 A V E +ef 44 107B 0 -33,-2.4 -31,-2.4 -2,-0.5 2,-0.3 -0.923 9.6 167.1-112.0 135.9 11.6 23.9 -5.9 77 76 A S E - f 0 108B 0 30,-1.8 32,-2.1 -2,-0.4 2,-0.3 -0.814 20.6-133.8-137.6-177.7 12.6 20.6 -4.4 78 77 A K E - f 0 109B 0 -2,-0.3 -31,-1.1 30,-0.2 2,-0.5 -0.999 15.5-119.4-144.9 140.5 11.7 17.0 -5.0 79 78 A L E - f 0 110B 0 30,-2.9 32,-1.8 -2,-0.3 33,-0.4 -0.656 39.1-128.3 -78.3 119.3 10.7 13.9 -3.0 80 79 A W > - 0 0 8 -2,-0.5 3,-1.9 31,-0.1 -1,-0.1 -0.285 19.9-108.2 -76.4 159.1 13.3 11.1 -3.7 81 80 A C G > S+ 0 0 0 1,-0.3 35,-2.4 2,-0.2 3,-0.8 0.685 114.0 62.0 -60.4 -29.6 12.2 7.6 -4.8 82 81 A T G 3 S+ 0 0 2 1,-0.2 37,-0.3 33,-0.2 -1,-0.3 0.401 100.4 56.8 -77.4 2.2 13.1 6.0 -1.5 83 82 A Y G < + 0 0 60 -3,-1.9 -1,-0.2 1,-0.1 -2,-0.2 0.006 65.9 112.9-123.1 25.9 10.5 8.1 0.4 84 83 A H < + 0 0 3 -3,-0.8 53,-0.2 32,-0.3 60,-0.1 0.731 46.0 105.9 -75.0 -18.9 7.3 7.3 -1.5 85 84 A E S >> S- 0 0 46 1,-0.1 3,-2.5 -3,-0.1 4,-0.9 -0.363 81.0-123.4 -61.5 138.3 5.7 5.6 1.5 86 85 A K H >> S+ 0 0 145 1,-0.3 3,-0.7 2,-0.2 4,-0.5 0.831 109.6 55.6 -55.8 -38.0 3.0 7.8 2.9 87 86 A G H 34 S+ 0 0 74 1,-0.2 -1,-0.3 2,-0.1 4,-0.3 0.574 108.8 47.8 -69.2 -13.6 4.6 7.7 6.4 88 87 A L H <> S+ 0 0 66 -3,-2.5 4,-2.0 -5,-0.1 -1,-0.2 0.555 89.0 82.9-101.4 -14.5 8.0 9.0 5.0 89 88 A V H S+ 0 0 45 -4,-0.3 4,-2.1 1,-0.2 -1,-0.2 0.896 110.0 50.3 -61.0 -39.9 10.0 13.7 7.0 92 91 A A H X S+ 0 0 10 -4,-2.0 4,-1.9 2,-0.2 -1,-0.2 0.920 112.0 47.5 -63.5 -42.6 11.6 13.9 3.6 93 92 A C H X S+ 0 0 0 -4,-2.4 4,-2.6 1,-0.2 -2,-0.2 0.926 112.0 49.9 -63.7 -45.9 10.1 17.3 3.0 94 93 A Q H X S+ 0 0 96 -4,-2.9 4,-2.6 1,-0.2 -1,-0.2 0.847 107.0 54.7 -65.8 -33.3 11.2 18.6 6.4 95 94 A K H X S+ 0 0 100 -4,-2.1 4,-2.6 2,-0.2 -1,-0.2 0.910 109.9 47.4 -62.6 -45.4 14.7 17.3 5.8 96 95 A T H X S+ 0 0 0 -4,-1.9 4,-2.8 2,-0.2 -2,-0.2 0.926 112.3 49.5 -59.3 -46.3 14.8 19.4 2.6 97 96 A L H X>S+ 0 0 13 -4,-2.6 5,-1.9 2,-0.2 4,-0.9 0.915 112.0 48.7 -59.2 -46.2 13.4 22.4 4.4 98 97 A S H ><5S+ 0 0 84 -4,-2.6 3,-0.7 1,-0.2 -2,-0.2 0.943 113.3 46.4 -60.1 -46.9 16.0 22.0 7.2 99 98 A D H 3<5S+ 0 0 12 -4,-2.6 -43,-0.2 1,-0.2 -2,-0.2 0.908 115.6 45.0 -63.0 -44.9 18.8 21.7 4.7 100 99 A L H 3<5S- 0 0 1 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.582 107.0-129.3 -73.5 -8.7 17.6 24.7 2.6 101 100 A K T <<5 + 0 0 74 -4,-0.9 2,-0.3 -3,-0.7 -3,-0.2 0.796 64.3 131.5 59.1 39.5 17.0 26.7 5.9 102 101 A L < - 0 0 21 -5,-1.9 -1,-0.2 -6,-0.2 -2,-0.1 -0.761 59.1-148.0-116.8 155.6 13.5 27.5 4.7 103 102 A D S S+ 0 0 129 -2,-0.3 2,-0.3 1,-0.3 -1,-0.1 0.555 84.9 12.5-100.2 -8.8 10.1 27.3 6.3 104 103 A Y - 0 0 48 -7,-0.1 2,-0.4 3,-0.0 -1,-0.3 -0.973 65.2-133.3-151.6 159.9 8.3 26.5 3.1 105 104 A L B -k 154 0C 0 48,-1.9 50,-2.5 -2,-0.3 51,-0.3 -0.866 12.7-142.4-102.9 149.4 8.9 25.5 -0.5 106 105 A D S S+ 0 0 6 -31,-1.6 2,-0.3 -2,-0.4 -30,-0.2 0.821 89.5 7.6 -72.9 -32.2 7.2 27.2 -3.4 107 106 A L E -f 76 0B 1 -32,-1.4 -30,-1.8 48,-0.2 2,-0.4 -0.964 62.3-167.0-154.1 135.4 6.9 23.9 -5.2 108 107 A Y E -fg 77 157B 2 48,-1.6 50,-2.1 -2,-0.3 2,-0.3 -0.999 15.9-163.3-129.0 126.8 7.5 20.2 -4.2 109 108 A L E -fg 78 158B 0 -32,-2.1 -30,-2.9 -2,-0.4 2,-0.7 -0.837 30.1-119.8-112.2 145.2 7.6 17.5 -6.9 110 109 A I E -fg 79 159B 2 48,-2.0 50,-1.1 -2,-0.3 -30,-0.1 -0.740 36.4-147.9 -72.3 112.4 7.4 13.7 -6.9 111 110 A H S S- 0 0 10 -32,-1.8 -1,-0.2 -2,-0.7 -31,-0.1 0.891 70.7 -2.8 -61.4 -45.2 10.8 13.3 -8.4 112 111 A W - 0 0 36 -33,-0.4 -1,-0.2 2,-0.2 49,-0.2 -0.974 68.0-122.5-139.5 154.1 10.1 10.2 -10.4 113 112 A P S S+ 0 0 3 0, 0.0 2,-0.3 0, 0.0 197,-0.1 0.715 88.0 90.5 -72.0 -17.3 6.9 8.0 -10.5 114 113 A V - 0 0 3 195,-0.1 2,-0.4 194,-0.0 -2,-0.2 -0.603 66.2-149.6 -83.2 130.4 8.9 5.0 -9.4 115 114 A G - 0 0 0 -2,-0.3 19,-1.9 19,-0.3 2,-0.3 -0.834 12.6-157.1 -97.9 140.6 9.2 4.1 -5.7 116 115 A F B -L 133 0D 3 -35,-2.4 -32,-0.3 -2,-0.4 18,-0.1 -0.838 36.2 -75.6-113.1 155.1 12.3 2.3 -4.5 117 116 A K - 0 0 102 15,-2.8 17,-0.2 -2,-0.3 15,-0.1 -0.167 58.4-110.0 -45.4 127.3 13.0 0.2 -1.4 118 117 A P + 0 0 56 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.239 69.5 90.5 -64.4 147.1 13.3 2.6 1.7 119 118 A G S S- 0 0 40 -37,-0.3 -37,-0.1 1,-0.1 -3,-0.0 -0.902 86.8 -62.0 150.8-173.0 16.7 2.9 3.2 120 119 A K S S+ 0 0 100 -2,-0.3 2,-0.2 3,-0.0 -1,-0.1 0.842 101.5 86.0 -73.0 -35.3 20.0 4.9 3.1 121 120 A E - 0 0 55 1,-0.1 -2,-0.0 -3,-0.1 0, 0.0 -0.475 66.4-150.3 -72.3 135.3 20.9 4.0 -0.5 122 121 A F S S+ 0 0 46 1,-0.3 -1,-0.1 -2,-0.2 -41,-0.1 0.817 95.6 30.4 -70.4 -34.3 19.4 6.3 -3.1 123 122 A F S S- 0 0 89 -42,-0.0 2,-0.4 -41,-0.0 -1,-0.3 -0.779 80.3-164.5-125.8 79.2 19.5 3.4 -5.7 124 123 A P - 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