==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-JAN-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE/LYASE INHIBITOR 08-APR-10 3MHM . COMPND 2 MOLECULE: CARBONIC ANHYDRASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.GRAZULIS,E.MANAKOVA,D.GOLOVENKO . 257 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11774.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 162 63.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 56 21.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 22 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A H 0 0 190 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -53.7 10.2 0.0 8.8 2 5 A W + 0 0 54 1,-0.1 2,-0.2 11,-0.1 7,-0.2 -0.262 360.0 127.8 -67.2 156.3 7.9 -1.5 11.3 3 6 A G - 0 0 6 5,-2.4 10,-0.1 2,-0.1 -1,-0.1 -0.793 66.9 -69.4-172.3-146.4 5.5 -4.4 10.5 4 7 A Y S S+ 0 0 36 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.466 84.0 103.9-113.2 -0.9 4.6 -7.8 11.6 5 8 A G S > S- 0 0 34 4,-0.1 4,-2.5 1,-0.1 -2,-0.1 0.053 83.1 -89.5 -74.9-177.6 7.7 -10.1 10.8 6 9 A K T 4 S+ 0 0 159 1,-0.2 -1,-0.1 2,-0.2 5,-0.0 0.888 127.0 30.9 -54.6 -42.3 10.6 -11.8 12.5 7 10 A H T 4 S+ 0 0 139 1,-0.1 -1,-0.2 5,-0.0 -3,-0.0 0.545 134.9 24.8-104.0 -6.7 12.8 -8.8 12.0 8 11 A N T 4 S+ 0 0 50 -6,-0.1 -5,-2.4 5,-0.0 -2,-0.2 0.310 93.2 112.7-135.4 12.9 10.2 -5.9 12.2 9 12 A G S >X S- 0 0 0 -4,-2.5 3,-2.7 -5,-0.2 4,-0.6 0.143 85.8 -64.1 -82.1-169.8 7.3 -7.2 14.2 10 13 A P G >4 S+ 0 0 22 0, 0.0 3,-0.9 0, 0.0 4,-0.4 0.762 127.7 59.3 -48.4 -36.7 5.9 -6.3 17.6 11 14 A E G 34 S+ 0 0 117 1,-0.3 3,-0.1 2,-0.1 -2,-0.1 0.609 109.0 46.7 -70.7 -13.6 8.9 -7.4 19.6 12 15 A H G X> S+ 0 0 49 -3,-2.7 3,-1.7 1,-0.1 4,-0.6 0.527 85.8 89.4 -94.9 -16.2 11.0 -4.9 17.7 13 16 A W H XX S+ 0 0 5 -3,-0.9 4,-2.6 -4,-0.6 3,-0.7 0.783 72.9 70.0 -62.8 -30.2 8.8 -1.9 17.9 14 17 A H H 34 S+ 0 0 66 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.731 88.2 65.9 -60.5 -25.6 10.2 -0.6 21.2 15 18 A K H <4 S+ 0 0 136 -3,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.916 117.1 24.5 -66.8 -41.4 13.5 0.4 19.4 16 19 A D H << S+ 0 0 100 -3,-0.7 -2,-0.2 -4,-0.6 -1,-0.2 0.748 135.8 36.1 -86.2 -25.8 11.8 3.1 17.2 17 20 A F >< - 0 0 54 -4,-2.6 3,-2.4 1,-0.1 -1,-0.2 -0.783 65.9-175.1-133.2 86.5 8.9 3.7 19.7 18 21 A P G > S+ 0 0 102 0, 0.0 3,-1.8 0, 0.0 -4,-0.1 0.687 79.0 72.5 -61.2 -25.1 10.0 3.4 23.4 19 22 A I G > S+ 0 0 65 1,-0.3 3,-3.3 179,-0.2 5,-0.2 0.641 72.0 89.8 -60.6 -12.6 6.4 3.8 24.8 20 23 A A G < S+ 0 0 8 -3,-2.4 -1,-0.3 1,-0.3 -6,-0.1 0.788 93.3 43.5 -53.9 -26.3 6.0 0.2 23.5 21 24 A K G < S+ 0 0 140 -3,-1.8 -1,-0.3 -7,-0.1 -2,-0.2 0.074 98.8 129.3-101.8 28.0 7.2 -0.7 27.0 22 25 A G S < S- 0 0 13 -3,-3.3 3,-0.5 1,-0.1 -3,-0.1 0.180 72.3-100.0 -81.5-171.8 5.0 1.9 28.6 23 26 A E S S+ 0 0 130 1,-0.2 226,-0.3 225,-0.1 227,-0.3 0.585 112.4 33.3 -87.4 -12.5 2.5 1.9 31.5 24 27 A R S S+ 0 0 47 -5,-0.2 -1,-0.2 224,-0.1 2,-0.2 -0.265 79.2 154.7-141.8 56.9 -0.8 1.7 29.6 25 28 A Q - 0 0 4 -3,-0.5 220,-0.2 221,-0.3 170,-0.1 -0.503 32.4-102.5 -87.5 152.0 -0.1 -0.3 26.4 26 29 A S S S+ 0 0 0 168,-0.4 2,-0.2 -2,-0.2 -2,-0.0 -0.889 76.5 42.3-126.6 161.7 -2.7 -2.3 24.4 27 30 A P + 0 0 0 0, 0.0 218,-2.8 0, 0.0 2,-0.3 0.579 65.3 178.3 -78.4-178.1 -4.0 -4.9 23.7 28 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.4 -0.911 35.8-100.3-139.4 159.8 -4.4 -6.8 27.0 29 32 A D E -a 105 0A 29 216,-0.4 2,-0.9 -2,-0.3 77,-0.2 -0.738 34.8-138.1 -76.9 134.2 -5.8 -10.1 28.1 30 33 A I E -a 106 0A 0 75,-3.1 77,-2.9 -2,-0.4 2,-1.0 -0.829 10.6-158.6 -98.2 104.7 -9.3 -9.6 29.6 31 34 A D >> - 0 0 67 -2,-0.9 4,-1.5 75,-0.2 3,-0.6 -0.769 6.0-161.7 -83.3 104.3 -9.5 -11.8 32.7 32 35 A T T 34 S+ 0 0 44 -2,-1.0 -1,-0.2 1,-0.3 222,-0.0 0.765 85.9 52.9 -69.7 -23.3 -13.3 -12.0 33.0 33 36 A H T 34 S+ 0 0 168 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.823 113.3 43.8 -79.4 -30.1 -13.3 -13.2 36.6 34 37 A T T <4 S+ 0 0 99 -3,-0.6 -2,-0.2 2,-0.1 -1,-0.2 0.605 86.8 105.3 -85.3 -17.0 -11.0 -10.2 37.7 35 38 A A S < S- 0 0 16 -4,-1.5 2,-0.6 1,-0.1 218,-0.2 -0.410 73.1-128.9 -67.6 140.5 -12.8 -7.5 35.7 36 39 A K E -c 253 0B 125 216,-2.3 218,-2.4 -2,-0.0 2,-0.2 -0.824 11.0-129.2 -98.5 122.0 -14.9 -5.4 38.2 37 40 A Y E -c 254 0B 105 -2,-0.6 218,-0.2 216,-0.2 220,-0.1 -0.515 22.8-160.4 -65.5 134.1 -18.6 -4.8 37.4 38 41 A D > - 0 0 26 216,-2.6 3,-1.9 -2,-0.2 -1,-0.0 -0.927 11.8-168.4-122.1 101.4 -19.2 -1.0 37.7 39 42 A P T 3 S+ 0 0 98 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.695 87.0 64.4 -65.6 -16.2 -22.9 -0.3 38.2 40 43 A S T 3 S+ 0 0 90 -3,-0.1 2,-0.3 2,-0.1 215,-0.1 0.520 76.3 105.9 -84.6 -5.5 -22.2 3.4 37.6 41 44 A L < - 0 0 28 -3,-1.9 3,-0.1 213,-0.2 38,-0.0 -0.557 66.9-136.4 -69.4 137.5 -21.1 2.7 33.9 42 45 A K - 0 0 128 37,-1.1 39,-0.1 -2,-0.3 3,-0.1 -0.504 26.5 -85.8 -91.7 163.5 -23.7 3.9 31.4 43 46 A P - 0 0 108 0, 0.0 36,-2.0 0, 0.0 2,-0.2 -0.372 52.8-107.0 -55.8 144.6 -25.1 2.1 28.3 44 47 A L E -D 78 0B 13 141,-0.3 2,-0.7 34,-0.2 34,-0.2 -0.550 28.2-144.0 -76.6 139.7 -22.9 2.8 25.3 45 48 A S E -D 77 0B 44 32,-3.1 32,-2.1 -2,-0.2 2,-0.6 -0.923 18.7-178.8-108.6 112.1 -24.5 5.2 22.8 46 49 A V E -D 76 0B 32 -2,-0.7 2,-0.7 30,-0.2 30,-0.2 -0.921 1.2-179.2-110.5 111.9 -23.6 4.4 19.2 47 50 A S E +D 75 0B 44 28,-2.9 28,-2.0 -2,-0.6 3,-0.2 -0.820 23.1 144.3-119.2 87.6 -25.2 6.9 16.8 48 51 A Y > + 0 0 3 -2,-0.7 3,-1.9 26,-0.2 130,-0.2 0.342 31.4 111.4-108.6 4.6 -24.3 5.8 13.3 49 52 A D T 3 S+ 0 0 99 1,-0.3 -1,-0.1 127,-0.1 25,-0.1 0.804 87.1 37.9 -48.1 -34.6 -27.5 6.8 11.4 50 53 A Q T 3 S+ 0 0 128 23,-1.0 -1,-0.3 -3,-0.2 24,-0.2 0.212 82.4 147.6-110.2 16.9 -25.8 9.6 9.4 51 54 A A < - 0 0 25 -3,-1.9 2,-0.5 22,-0.2 23,-0.1 -0.221 32.4-157.8 -48.9 139.0 -22.4 8.0 8.8 52 55 A T - 0 0 47 16,-0.3 16,-2.8 121,-0.1 2,-0.2 -0.899 4.7-165.5-124.2 94.0 -20.6 9.0 5.6 53 56 A S E +E 67 0B 1 -2,-0.5 121,-0.6 122,-0.3 14,-0.3 -0.556 10.7 175.3 -73.8 150.4 -18.1 6.5 4.5 54 57 A L E - 0 0 80 12,-3.2 118,-2.2 1,-0.4 2,-0.3 0.684 51.0 -6.9-120.2 -39.4 -15.8 7.9 1.7 55 58 A R E -EF 66 171B 80 11,-1.1 11,-2.9 116,-0.3 -1,-0.4 -0.992 47.0-133.2-160.8 157.2 -13.0 5.5 0.8 56 59 A I E -EF 65 170B 0 114,-2.6 114,-2.3 -2,-0.3 2,-0.4 -0.982 27.9-169.8-125.0 138.7 -11.2 2.3 1.6 57 60 A L E -EF 64 169B 33 7,-2.2 7,-2.6 -2,-0.4 2,-0.7 -0.989 25.9-146.1-135.7 132.2 -7.4 2.1 1.7 58 61 A N E +E 63 0B 0 110,-2.8 109,-3.1 -2,-0.4 5,-0.2 -0.901 22.6 179.1 -88.9 109.0 -4.7 -0.6 1.9 59 62 A N - 0 0 53 3,-2.0 4,-0.1 -2,-0.7 -1,-0.1 0.275 52.9-102.1-101.4 12.8 -2.1 1.2 4.1 60 63 A G S S+ 0 0 6 2,-0.5 106,-0.1 166,-0.2 3,-0.1 0.360 116.7 56.0 84.0 -2.7 0.3 -1.7 4.1 61 64 A H S S- 0 0 43 1,-0.6 2,-0.3 -58,-0.1 166,-0.1 0.482 124.4 -31.5-133.9 -23.8 -0.6 -2.9 7.6 62 65 A A S S- 0 0 5 31,-0.1 -3,-2.0 165,-0.1 -1,-0.6 -0.917 72.0 -87.6-166.5-166.9 -4.4 -3.4 7.3 63 66 A F E -E 58 0B 0 29,-0.3 29,-0.5 -2,-0.3 2,-0.5 -0.986 35.7-152.4-118.5 137.4 -7.3 -1.8 5.3 64 67 A N E -E 57 0B 24 -7,-2.6 -7,-2.2 -2,-0.4 2,-0.6 -0.922 9.1-154.1-107.5 129.1 -9.1 1.3 6.6 65 68 A V E -EG 56 90B 0 25,-2.7 25,-2.0 -2,-0.5 2,-0.3 -0.940 29.7-153.5 -95.1 116.9 -12.7 2.3 5.8 66 69 A E E -EG 55 89B 43 -11,-2.9 -12,-3.2 -2,-0.6 -11,-1.1 -0.707 10.0-159.6-102.5 149.6 -12.6 6.1 6.2 67 70 A F E -E 53 0B 9 21,-2.5 2,-0.8 -2,-0.3 -14,-0.2 -0.837 31.2-101.9-122.9 157.5 -15.4 8.4 7.1 68 71 A D + 0 0 37 -16,-2.8 -16,-0.3 -2,-0.3 3,-0.3 -0.691 40.7 173.2 -75.9 114.8 -16.2 12.1 6.8 69 72 A D + 0 0 43 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 -0.036 46.8 105.8-113.8 30.3 -15.5 13.3 10.4 70 73 A S S S+ 0 0 84 2,-0.0 2,-0.3 56,-0.0 -1,-0.2 0.422 87.8 26.6 -93.5 2.8 -15.9 17.1 9.6 71 74 A Q S S- 0 0 116 -3,-0.3 2,-1.1 3,-0.1 3,-0.4 -0.933 100.2 -87.3-149.2 166.5 -19.3 17.1 11.3 72 75 A D S S+ 0 0 91 -2,-0.3 3,-0.1 1,-0.2 -3,-0.1 -0.709 77.7 124.5 -77.6 98.9 -21.0 15.1 14.1 73 76 A K S S+ 0 0 45 -2,-1.1 -23,-1.0 1,-0.2 2,-0.4 0.500 72.6 26.1-124.7 -35.4 -22.5 12.4 11.9 74 77 A A S S+ 0 0 6 -3,-0.4 13,-3.3 -24,-0.2 2,-0.3 -0.846 84.5 166.9-133.6 104.5 -21.3 9.1 13.3 75 78 A V E -DH 47 86B 13 -28,-2.0 -28,-2.9 -2,-0.4 2,-0.4 -0.903 31.1-150.9-131.9 149.4 -20.5 9.4 17.1 76 79 A L E +DH 46 85B 0 9,-2.9 9,-2.6 -2,-0.3 2,-0.3 -0.947 32.2 143.8-109.0 135.8 -19.8 7.4 20.2 77 80 A K E +D 45 0B 60 -32,-2.1 -32,-3.1 -2,-0.4 7,-0.1 -0.904 38.0 39.6-154.7-177.2 -20.7 8.7 23.6 78 81 A G E > S+D 44 0B 11 5,-0.4 3,-2.5 3,-0.3 -34,-0.2 -0.316 74.1 90.0 67.4-149.6 -22.0 7.5 27.0 79 82 A G T 3 S- 0 0 4 -36,-2.0 -37,-1.1 1,-0.3 -1,-0.1 -0.410 121.1 -28.9 61.3-134.8 -20.5 4.2 28.2 80 83 A P T 3 S+ 0 0 39 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.456 117.6 108.0 -87.3 2.5 -17.4 5.2 30.2 81 84 A L < - 0 0 14 -3,-2.5 2,-0.4 -39,-0.1 -3,-0.3 -0.477 57.7-149.3 -91.5 150.2 -16.8 8.4 28.1 82 85 A D S S- 0 0 143 -2,-0.2 -1,-0.0 -5,-0.1 2,-0.0 -0.930 71.0 -6.6-102.6 141.7 -17.3 12.1 28.8 83 86 A G S S- 0 0 52 -2,-0.4 -5,-0.4 38,-0.1 2,-0.4 -0.302 99.4 -46.1 69.9-165.9 -18.3 14.1 25.8 84 87 A T - 0 0 34 -7,-0.1 38,-2.6 -9,-0.0 2,-0.4 -0.867 38.1-161.1-125.1 133.6 -18.5 13.1 22.2 85 88 A Y E -HI 76 121B 5 -9,-2.6 -9,-2.9 -2,-0.4 2,-0.4 -0.978 14.0-142.1-121.6 127.6 -16.2 11.1 19.9 86 89 A R E -HI 75 120B 42 34,-2.6 34,-2.0 -2,-0.4 2,-0.3 -0.746 20.2-118.0 -91.7 133.6 -16.4 11.1 16.1 87 90 A L E + I 0 119B 2 -13,-3.3 32,-0.2 -2,-0.4 -13,-0.1 -0.484 37.1 167.0 -68.5 128.0 -15.9 8.1 13.9 88 91 A I E - 0 0 37 30,-2.7 -21,-2.5 1,-0.4 2,-0.3 0.768 60.6 -28.1-110.2 -37.8 -12.8 8.6 11.6 89 92 A Q E -GI 66 118B 30 29,-1.2 29,-3.0 -23,-0.2 -1,-0.4 -0.987 47.6-142.2-167.2 161.7 -12.2 5.0 10.4 90 93 A F E +GI 65 117B 0 -25,-2.0 -25,-2.7 -2,-0.3 2,-0.3 -0.969 23.2 161.3-127.5 160.3 -12.5 1.3 11.1 91 94 A H E - I 0 116B 21 25,-1.9 25,-3.2 -2,-0.3 2,-0.3 -0.927 24.0-126.2-156.6 177.7 -10.1 -1.5 10.3 92 95 A F E - I 0 115B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.3 -0.858 0.8-146.5-130.0 163.0 -9.5 -5.1 11.4 93 96 A H E + I 0 114B 3 21,-2.0 21,-2.2 -2,-0.3 2,-0.3 -0.985 32.3 169.7-123.5 139.0 -6.7 -7.3 12.6 94 97 A W E - I 0 113B 0 -2,-0.4 146,-1.2 19,-0.2 145,-1.0 -0.922 22.8-117.2-149.3 168.2 -6.8 -11.0 11.6 95 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.6 3,-0.1 -0.459 23.5-120.2-104.9 176.3 -4.8 -14.2 11.5 96 99 A S S S+ 0 0 44 -2,-0.2 2,-0.3 142,-0.2 5,-0.1 0.572 106.2 28.8 -80.6 -17.0 -3.3 -16.8 9.1 97 100 A L S > S- 0 0 105 3,-0.3 3,-1.6 15,-0.1 -2,-0.2 -0.947 90.1-109.1-140.6 158.8 -5.6 -19.4 10.7 98 101 A D T 3 S+ 0 0 75 -2,-0.3 48,-0.1 1,-0.3 15,-0.1 0.760 110.9 67.9 -67.1 -23.5 -9.0 -19.2 12.4 99 102 A G T 3 S+ 0 0 58 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.398 106.9 31.2 -78.0 6.5 -7.5 -19.8 15.9 100 103 A Q < + 0 0 54 -3,-1.6 -5,-0.6 12,-0.1 -3,-0.3 -0.959 66.4 95.5-153.8 162.1 -5.6 -16.5 16.0 101 104 A G + 0 0 0 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 -0.089 55.5 107.3 143.7 -34.7 -6.0 -12.9 14.8 102 105 A S - 0 0 1 9,-2.1 -1,-0.6 11,-0.3 -8,-0.1 -0.375 51.7-154.4 -71.0 158.3 -7.6 -10.9 17.7 103 106 A E S S+ 0 0 1 -10,-0.1 -1,-0.1 -3,-0.1 141,-0.1 0.883 82.7 52.6 -93.2 -58.8 -5.5 -8.4 19.6 104 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 -75,-0.1 2,-0.3 -0.463 77.8-157.7 -68.1 154.1 -7.5 -8.5 22.9 105 108 A T E -a 29 0A 9 -77,-1.2 -75,-3.1 5,-0.1 2,-0.5 -0.906 11.0-138.1-128.6 160.8 -8.0 -11.9 24.3 106 109 A V E > S-aB 30 109A 18 3,-1.8 3,-2.3 -2,-0.3 -75,-0.2 -0.960 88.5 -21.5-124.3 111.7 -10.7 -13.1 26.8 107 110 A D T 3 S- 0 0 70 -77,-2.9 -1,-0.2 -2,-0.5 -76,-0.1 0.898 128.9 -54.6 46.9 44.2 -9.4 -15.5 29.5 108 111 A K T 3 S+ 0 0 157 1,-0.3 2,-0.3 -78,-0.1 -1,-0.3 0.302 104.9 140.6 71.8 0.1 -6.5 -16.1 27.0 109 112 A K B < -B 106 0A 113 -3,-2.3 -3,-1.8 -9,-0.0 2,-0.4 -0.541 41.0-150.0 -73.8 127.1 -9.0 -17.1 24.2 110 113 A K - 0 0 91 -2,-0.3 2,-0.2 -11,-0.2 -5,-0.1 -0.774 7.4-149.7 -87.6 137.7 -7.9 -15.7 20.7 111 114 A Y - 0 0 29 -7,-0.4 -9,-2.1 -2,-0.4 34,-0.2 -0.623 28.3-107.2 -97.3 167.2 -10.7 -14.9 18.2 112 115 A A S S- 0 0 4 32,-1.1 -17,-1.4 -2,-0.2 2,-0.3 0.726 93.1 -17.7 -63.8 -27.8 -10.2 -15.1 14.4 113 116 A A E -IJ 94 144B 0 31,-1.3 31,-2.7 -19,-0.2 2,-0.4 -0.968 58.3-137.0-163.4 173.7 -10.1 -11.3 14.0 114 117 A E E -IJ 93 143B 0 -21,-2.2 -21,-2.0 -13,-0.3 2,-0.4 -0.979 12.2-144.4-147.9 132.6 -11.0 -8.1 15.8 115 118 A L E -IJ 92 142B 0 27,-3.0 27,-2.3 -2,-0.4 2,-0.5 -0.817 11.4-159.8 -94.0 138.3 -12.7 -5.0 14.4 116 119 A H E -IJ 91 141B 2 -25,-3.2 -25,-1.9 -2,-0.4 2,-0.7 -0.973 5.0-165.1-123.6 118.1 -11.6 -1.5 15.6 117 120 A L E -IJ 90 140B 0 23,-2.6 23,-2.4 -2,-0.5 2,-0.5 -0.921 20.6-151.1-100.1 108.9 -13.9 1.5 15.2 118 121 A V E +IJ 89 139B 7 -29,-3.0 -30,-2.7 -2,-0.7 -29,-1.2 -0.808 19.5 175.3 -96.3 126.9 -11.7 4.5 15.8 119 122 A H E -IJ 87 138B 0 19,-1.9 19,-2.6 -2,-0.5 2,-0.4 -0.963 16.4-147.4-130.9 146.2 -13.2 7.7 17.2 120 123 A W E -IJ 86 137B 6 -34,-2.0 -34,-2.6 -2,-0.3 2,-0.4 -0.883 27.8-105.8-119.0 149.2 -11.6 11.0 18.4 121 124 A N E > -I 85 0B 4 15,-3.2 3,-2.4 -2,-0.4 -36,-0.2 -0.509 21.4-146.5 -75.9 120.7 -12.8 13.4 21.1 122 125 A T G > S+ 0 0 44 -38,-2.6 3,-1.2 -2,-0.4 -1,-0.2 0.668 91.7 76.8 -64.7 -15.0 -14.3 16.4 19.6 123 127 A K G 3 S+ 0 0 131 -39,-0.3 -1,-0.3 1,-0.2 -2,-0.1 0.696 95.6 52.3 -67.3 -13.4 -13.0 18.7 22.5 124 128 A Y G < S- 0 0 49 -3,-2.4 2,-1.1 12,-0.1 -1,-0.2 0.419 102.1-135.5-103.5 1.6 -9.6 18.4 20.7 125 129 A G S < S+ 0 0 56 -3,-1.2 2,-0.3 -4,-0.2 -3,-0.1 -0.038 71.7 23.0 83.5 -39.3 -10.8 19.5 17.2 126 130 A D S > S- 0 0 70 -2,-1.1 4,-2.3 -5,-0.2 3,-0.3 -0.975 79.6-105.6-154.5 166.5 -9.0 16.9 15.0 127 131 A F H > S+ 0 0 61 -2,-0.3 4,-2.2 1,-0.2 5,-0.2 0.868 114.3 57.8 -59.4 -46.1 -7.5 13.4 15.2 128 132 A G H 4 S+ 0 0 46 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.830 112.4 39.9 -60.2 -35.5 -3.9 14.6 15.1 129 133 A K H >4 S+ 0 0 125 -3,-0.3 3,-1.5 -5,-0.2 -1,-0.2 0.863 110.9 58.7 -77.4 -37.4 -4.4 16.7 18.2 130 134 A A H >< S+ 0 0 0 -4,-2.3 3,-2.0 1,-0.2 6,-0.2 0.882 96.2 61.4 -56.9 -38.3 -6.6 14.1 20.0 131 135 A V T 3< S+ 0 0 17 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.1 0.641 96.2 62.7 -68.1 -12.2 -3.8 11.4 19.8 132 136 A Q T < S+ 0 0 126 -3,-1.5 -1,-0.3 -4,-0.2 -2,-0.2 0.212 95.6 77.7 -92.2 12.3 -1.6 13.7 21.9 133 137 A Q S X S- 0 0 72 -3,-2.0 3,-1.8 69,-0.1 4,-0.3 -0.956 80.6-128.8-126.7 146.6 -4.1 13.5 24.9 134 138 A P T 3 S+ 0 0 76 0, 0.0 58,-0.1 0, 0.0 3,-0.1 0.729 114.9 33.3 -67.4 -20.7 -4.8 10.8 27.5 135 139 A D T 3 S+ 0 0 54 1,-0.1 68,-0.1 -5,-0.1 67,-0.1 -0.208 88.1 114.5-118.8 35.6 -8.5 10.9 26.7 136 140 A G S < S+ 0 0 0 -3,-1.8 -15,-3.2 66,-0.3 2,-0.3 0.824 71.1 36.3 -77.3 -35.1 -8.2 11.7 22.9 137 141 A L E -Jk 120 203B 0 65,-2.9 67,-2.5 -4,-0.3 2,-0.4 -0.878 53.3-161.4-124.3 151.9 -9.5 8.5 21.4 138 142 A A E -Jk 119 204B 0 -19,-2.6 -19,-1.9 -2,-0.3 2,-0.5 -0.990 15.5-166.5-127.5 118.7 -12.3 6.0 22.0 139 143 A V E -Jk 118 205B 4 65,-1.8 67,-2.5 -2,-0.4 2,-0.7 -0.976 8.4-153.8-108.8 126.6 -11.8 2.7 20.2 140 144 A L E -Jk 117 206B 0 -23,-2.4 -23,-2.6 -2,-0.5 2,-0.4 -0.867 16.4-161.8 -97.1 119.3 -14.8 0.3 20.0 141 145 A G E -Jk 116 207B 0 65,-3.0 67,-2.9 -2,-0.7 2,-0.4 -0.833 10.1-176.5-107.6 136.9 -13.4 -3.3 19.6 142 146 A I E -J 115 0B 0 -27,-2.3 -27,-3.0 -2,-0.4 2,-0.2 -0.988 19.6-133.9-135.0 129.5 -15.5 -6.2 18.4 143 147 A F E -J 114 0B 0 65,-0.4 69,-2.7 -2,-0.4 2,-0.5 -0.473 13.9-148.3 -81.5 149.8 -14.3 -9.8 18.1 144 148 A L E -Jl 113 212B 0 -31,-2.7 -31,-1.3 67,-0.2 -32,-1.1 -0.974 12.9-174.3-116.7 130.8 -15.0 -11.9 15.0 145 149 A K E - l 0 213B 103 67,-2.5 69,-2.4 -2,-0.5 2,-0.5 -0.862 30.2-111.5-112.4 159.8 -15.5 -15.6 15.1 146 150 A V E S+ l 0 214B 47 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.741 73.6 88.1 -95.8 129.6 -15.9 -17.9 12.1 147 151 A G S S+ 0 0 47 67,-3.0 69,-0.5 -2,-0.5 2,-0.1 -0.548 80.0 16.9-175.6-121.5 -19.4 -19.4 11.5 148 152 A S S S- 0 0 83 -2,-0.2 -1,-0.4 67,-0.1 2,-0.0 -0.425 88.2 -96.0 -70.4 154.0 -22.4 -17.9 9.7 149 153 A A - 0 0 52 65,-0.3 65,-0.2 -3,-0.1 64,-0.1 -0.325 23.3-130.8 -65.5 156.4 -21.7 -15.0 7.3 150 154 A K >> - 0 0 45 1,-0.2 3,-1.8 62,-0.1 4,-0.6 -0.912 16.9-161.7-104.8 105.2 -22.1 -11.4 8.4 151 155 A P G >4 S+ 0 0 112 0, 0.0 3,-1.6 0, 0.0 4,-0.4 0.915 87.9 60.1 -59.2 -32.5 -24.3 -10.0 5.5 152 156 A G G 34 S+ 0 0 25 27,-0.4 4,-0.2 1,-0.3 27,-0.2 0.569 102.4 54.5 -70.4 -14.3 -23.3 -6.4 6.5 153 157 A L G X> S+ 0 0 1 -3,-1.8 4,-2.2 26,-0.1 3,-0.6 0.596 83.2 86.3 -85.7 -18.3 -19.6 -7.2 5.9 154 158 A Q H S+ 0 0 108 -4,-0.4 4,-1.1 1,-0.2 -1,-0.2 0.919 110.3 46.8 -57.1 -38.9 -19.7 -5.0 0.6 156 160 A V H X> S+ 0 0 0 -3,-0.6 3,-1.0 -4,-0.2 4,-0.7 0.973 112.9 48.7 -67.1 -49.2 -16.3 -4.6 2.3 157 161 A V H >< S+ 0 0 0 -4,-2.2 3,-1.1 1,-0.3 4,-0.4 0.897 107.8 55.1 -55.9 -37.9 -15.2 -8.1 1.4 158 162 A D H 3< S+ 0 0 86 -4,-2.7 3,-0.3 1,-0.3 -1,-0.3 0.731 105.7 50.6 -78.6 -16.9 -16.2 -7.7 -2.2 159 163 A V H X< S+ 0 0 28 -4,-1.1 3,-1.6 -3,-1.0 4,-0.4 0.537 85.1 90.6 -89.2 -11.8 -14.1 -4.5 -2.8 160 164 A L G X< S+ 0 0 5 -3,-1.1 3,-1.4 -4,-0.7 -1,-0.2 0.814 76.0 62.3 -55.9 -35.2 -10.8 -6.0 -1.4 161 165 A D G > S+ 0 0 126 -4,-0.4 3,-0.7 -3,-0.3 -1,-0.3 0.792 100.1 57.5 -66.2 -17.4 -9.6 -7.4 -4.7 162 166 A S G < S+ 0 0 41 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.602 113.1 38.5 -84.1 -12.5 -9.5 -3.6 -5.9 163 167 A I G < S+ 0 0 0 -3,-1.4 63,-0.2 -4,-0.4 -1,-0.2 -0.217 74.4 140.0-127.6 46.3 -7.1 -2.7 -3.1 164 168 A K < + 0 0 88 -3,-0.7 62,-2.7 61,-0.1 2,-0.2 0.857 60.3 46.3 -61.9 -37.6 -4.9 -5.8 -3.0 165 169 A T S > S- 0 0 11 60,-0.2 3,-2.0 1,-0.1 -107,-0.3 -0.658 98.3 -76.2-117.8 157.2 -1.5 -4.0 -2.4 166 170 A K T 3 S+ 0 0 118 62,-2.6 64,-0.5 1,-0.3 -107,-0.2 -0.213 114.4 21.7 -46.2 130.0 -0.1 -1.3 -0.2 167 171 A G T 3 S+ 0 0 54 -109,-3.1 2,-0.3 1,-0.3 -1,-0.3 0.200 89.1 128.8 90.5 -12.3 -1.1 2.3 -1.3 168 172 A K < + 0 0 78 -3,-2.0 -110,-2.8 -110,-0.2 2,-0.3 -0.552 32.4 178.4 -75.6 141.1 -4.2 1.2 -3.2 169 173 A S E -F 57 0B 60 -2,-0.3 2,-0.3 -112,-0.2 -112,-0.2 -0.971 10.1-167.7-139.6 153.8 -7.5 3.0 -2.5 170 174 A A E -F 56 0B 22 -114,-2.3 -114,-2.6 -2,-0.3 -116,-0.0 -0.985 35.6 -97.0-139.9 144.4 -11.1 2.9 -3.8 171 175 A D E +F 55 0B 144 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.1 -0.376 41.1 179.0 -52.6 136.5 -14.2 5.0 -3.5 172 176 A F + 0 0 6 -118,-2.2 3,-0.4 -106,-0.1 2,-0.2 -0.564 11.6 163.0-147.3 76.2 -16.3 3.4 -0.8 173 177 A T + 0 0 72 1,-0.2 -119,-0.2 -119,-0.1 -121,-0.1 -0.602 53.2 24.5 -93.9 160.1 -19.5 5.5 -0.2 174 178 A N S S+ 0 0 147 -121,-0.6 2,-0.5 1,-0.2 -1,-0.2 0.700 73.4 153.2 67.0 28.1 -22.8 4.6 1.5 175 179 A F - 0 0 12 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.795 35.0-148.0 -91.1 128.8 -21.3 1.9 3.7 176 180 A D > - 0 0 65 -2,-0.5 3,-1.8 1,-0.1 -127,-0.1 -0.808 9.2-165.1-100.7 107.0 -23.4 1.5 6.9 177 181 A P G > S+ 0 0 0 0, 0.0 3,-2.1 0, 0.0 4,-0.2 0.662 80.2 80.7 -70.2 -8.8 -21.2 0.4 9.9 178 182 A R G > S+ 0 0 123 1,-0.3 3,-1.3 -130,-0.2 -26,-0.1 0.776 80.0 69.0 -59.8 -27.9 -24.3 -0.5 11.9 179 183 A G G < S+ 0 0 31 -3,-1.8 -27,-0.4 1,-0.2 -1,-0.3 0.454 94.9 56.9 -70.6 1.1 -24.3 -3.8 9.9 180 184 A L G < S+ 0 0 0 -3,-2.1 -1,-0.2 -28,-0.1 -2,-0.2 0.390 85.5 100.3-108.4 5.1 -21.1 -4.8 11.9 181 185 A L < - 0 0 32 -3,-1.3 4,-0.1 -4,-0.2 -39,-0.0 -0.686 67.0-131.1 -98.9 137.8 -22.5 -4.5 15.4 182 186 A P - 0 0 12 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.197 32.7-101.2 -73.3 179.0 -23.6 -7.5 17.5 183 187 A E S S+ 0 0 184 2,-0.0 2,-0.4 1,-0.0 29,-0.1 0.846 103.2 58.2 -71.8 -39.9 -27.0 -7.5 19.3 184 188 A S - 0 0 32 1,-0.1 26,-0.3 2,-0.1 -1,-0.0 -0.801 58.5-162.9 -96.3 143.0 -25.7 -6.7 22.7 185 189 A L + 0 0 59 -2,-0.4 -141,-0.3 23,-0.1 -1,-0.1 0.141 43.9 137.9-104.2 19.8 -23.6 -3.5 23.6 186 190 A D + 0 0 62 -143,-0.1 23,-2.3 22,-0.1 24,-0.5 -0.408 35.3 176.8 -58.1 140.4 -22.3 -5.0 27.0 187 191 A Y E -M 208 0B 1 21,-0.3 68,-2.8 22,-0.1 2,-0.3 -0.951 37.5-133.7-146.9 159.7 -18.7 -4.1 27.2 188 192 A W E -MN 207 254B 9 19,-2.7 19,-2.8 -2,-0.3 2,-0.3 -0.848 30.0-167.0-103.5 155.5 -15.4 -4.1 29.1 189 193 A T E +MN 206 253B 8 64,-2.6 64,-2.5 -2,-0.3 17,-0.2 -0.997 17.0 152.4-146.6 145.7 -13.4 -0.9 29.3 190 194 A Y E -M 205 0B 5 15,-1.4 15,-2.5 -2,-0.3 2,-0.4 -0.967 46.6 -96.1-160.8 160.2 -9.8 0.1 30.4 191 195 A P E +M 204 0B 54 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.724 62.0 131.5 -87.4 133.9 -7.3 2.9 29.5 192 196 A G E -M 203 0B 0 11,-3.2 11,-1.7 -2,-0.4 2,-0.3 -0.528 42.1 -92.9-153.3-146.7 -4.7 1.9 26.9 193 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.834 43.9 -73.3-137.3 170.8 -3.0 2.8 23.7 194 198 A L - 0 0 28 6,-2.2 -168,-0.4 -2,-0.3 9,-0.0 -0.491 40.2-140.5 -61.0 146.6 -2.9 2.5 19.9 195 199 A T S S+ 0 0 6 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.405 82.8 54.6 -97.5 0.8 -1.9 -1.0 19.1 196 200 A T S > S- 0 0 38 4,-0.1 3,-2.8 45,-0.0 4,-0.3 -0.942 103.5 -45.4-121.5 157.3 0.2 -0.0 16.1 197 201 A P T 3 S+ 0 0 11 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.297 124.6 43.8 -48.5 140.9 3.1 2.5 16.1 198 202 A P T 3 S- 0 0 60 0, 0.0 -179,-0.2 0, 0.0 -178,-0.0 -0.967 84.6-161.7 -83.1 12.3 3.2 5.3 17.3 199 203 A L < - 0 0 0 -3,-2.8 -173,-0.1 1,-0.2 -4,-0.0 0.770 19.5-173.2 61.7 24.8 1.6 3.3 20.2 200 204 A L - 0 0 42 -4,-0.3 -6,-2.2 -7,-0.1 2,-1.8 -0.265 29.4-127.5 -62.6 141.4 0.3 6.5 21.8 201 205 A E S S+ 0 0 46 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.460 76.9 108.3 -89.1 69.7 -1.3 6.2 25.2 202 206 A C + 0 0 1 -2,-1.8 -65,-2.9 -67,-0.1 2,-0.4 0.183 46.7 108.6-131.0 13.5 -4.5 8.1 24.2 203 207 A V E -kM 137 192B 0 -11,-1.7 -11,-3.2 -3,-0.3 2,-0.8 -0.832 48.0-160.2-114.7 128.2 -7.2 5.4 24.0 204 208 A T E -kM 138 191B 29 -67,-2.5 -65,-1.8 -2,-0.4 2,-0.4 -0.925 32.8-147.1 -86.3 114.3 -10.2 4.6 26.2 205 209 A W E -kM 139 190B 4 -15,-2.5 -15,-1.4 -2,-0.8 2,-0.5 -0.700 20.1-175.9 -85.5 137.6 -10.8 1.0 25.0 206 210 A I E -kM 140 189B 0 -67,-2.5 -65,-3.0 -2,-0.4 2,-0.5 -0.967 8.8-172.5-131.3 112.6 -14.4 -0.3 24.9 207 211 A V E -kM 141 188B 1 -19,-2.8 -19,-2.7 -2,-0.5 2,-0.2 -0.926 19.8-130.7-114.8 117.1 -14.4 -4.0 24.0 208 212 A L E - M 0 187B 0 -67,-2.9 -65,-0.4 -2,-0.5 -21,-0.3 -0.513 3.7-146.3 -66.7 139.9 -17.8 -5.7 23.3 209 213 A K S S+ 0 0 73 -23,-2.3 -1,-0.1 -2,-0.2 -22,-0.1 0.831 82.0 69.7 -69.1 -38.8 -18.5 -9.0 25.1 210 214 A E S S- 0 0 67 -24,-0.5 -67,-0.1 -26,-0.3 -2,-0.1 -0.765 75.6-147.7 -90.6 125.7 -20.5 -10.5 22.2 211 215 A P - 0 0 27 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.318 11.1-125.3 -77.8 168.6 -18.6 -11.4 19.0 212 216 A I E -l 144 0B 3 -69,-2.7 -67,-2.5 -30,-0.1 2,-0.4 -0.818 22.4-125.6-103.8 153.6 -20.0 -11.2 15.5 213 217 A S E +l 145 0B 30 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.817 28.0 178.2 -95.3 138.8 -19.9 -14.2 13.2 214 218 A V E -l 146 0B 2 -69,-2.4 -67,-3.0 -2,-0.4 -65,-0.3 -0.936 31.2-105.2-128.9 157.5 -18.4 -14.0 9.8 215 219 A S > - 0 0 11 -2,-0.3 4,-2.2 -69,-0.2 5,-0.3 -0.461 22.8-115.9 -82.5 161.2 -18.0 -16.9 7.3 216 220 A S H > S+ 0 0 52 -69,-0.5 4,-2.2 1,-0.2 5,-0.1 0.911 119.3 54.8 -55.2 -37.9 -14.8 -18.8 6.4 217 221 A E H > S+ 0 0 129 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.894 105.9 50.5 -67.6 -37.2 -15.2 -17.4 2.9 218 222 A Q H > S+ 0 0 2 2,-0.2 4,-1.2 1,-0.2 3,-0.4 0.950 114.1 42.4 -67.0 -46.6 -15.3 -13.7 4.2 219 223 A V H X S+ 0 0 2 -4,-2.2 4,-1.6 1,-0.2 -2,-0.2 0.811 107.8 62.7 -73.6 -23.3 -12.1 -14.1 6.4 220 224 A L H < S+ 0 0 91 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.2 0.886 100.2 53.6 -57.1 -41.3 -10.5 -16.0 3.5 221 225 A K H >< S+ 0 0 83 -4,-1.4 3,-1.2 -3,-0.4 4,-0.3 0.841 103.2 55.8 -68.2 -33.5 -10.8 -12.8 1.4 222 226 A F H >< S+ 0 0 1 -4,-1.2 3,-1.6 1,-0.2 -1,-0.2 0.915 103.9 55.6 -56.9 -41.9 -9.0 -10.8 4.1 223 227 A R T 3< S+ 0 0 30 -4,-1.6 -1,-0.2 1,-0.3 -2,-0.2 0.471 95.1 66.8 -75.7 -2.4 -6.1 -13.2 3.9 224 228 A K T < S+ 0 0 142 -3,-1.2 -1,-0.3 -4,-0.2 -2,-0.2 0.509 80.0 101.7 -89.9 -9.9 -5.7 -12.6 0.1 225 229 A L < - 0 0 4 -3,-1.6 12,-2.8 -4,-0.3 2,-0.4 -0.238 69.2-129.5 -65.2 168.2 -4.7 -9.0 0.7 226 230 A N B -O 236 0C 5 -62,-2.7 10,-0.2 10,-0.3 -166,-0.2 -0.944 16.0-156.0-125.6 138.5 -1.0 -8.1 0.4 227 231 A F S S+ 0 0 36 8,-2.8 -1,-0.1 -2,-0.4 9,-0.1 0.784 81.2 76.7 -76.1 -30.4 1.3 -6.2 2.8 228 232 A N S S- 0 0 5 7,-0.6 -62,-2.6 5,-0.1 2,-0.1 -0.318 86.2-111.0 -73.5 163.4 3.6 -5.3 -0.2 229 233 A G > - 0 0 8 -64,-0.3 3,-1.2 1,-0.2 -62,-0.1 -0.471 51.4 -71.6 -86.7 165.8 3.0 -2.7 -3.0 230 234 A E T 3 S+ 0 0 154 -64,-0.5 -1,-0.2 1,-0.3 4,-0.0 -0.301 121.9 26.6 -56.2 139.0 2.1 -3.6 -6.6 231 235 A G T 3 S+ 0 0 87 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.0 0.623 101.9 107.3 79.5 15.9 5.1 -5.0 -8.5 232 236 A E S < S- 0 0 111 -3,-1.2 -1,-0.3 1,-0.1 -4,-0.1 -0.782 85.2 -76.2-120.6 161.1 6.8 -6.3 -5.3 233 237 A P - 0 0 108 0, 0.0 2,-0.4 0, 0.0 -5,-0.1 -0.387 61.8-100.2 -57.1 135.0 7.2 -9.9 -4.0 234 238 A E + 0 0 117 -7,-0.1 2,-0.5 -8,-0.1 -8,-0.0 -0.495 42.3 176.8 -72.6 125.0 3.8 -11.1 -2.6 235 239 A E - 0 0 101 -2,-0.4 -8,-2.8 -3,-0.1 -7,-0.6 -0.984 29.5-130.5-121.7 109.0 3.5 -11.0 1.2 236 240 A L B -O 226 0C 86 -2,-0.5 2,-1.5 -10,-0.2 -10,-0.3 -0.475 18.6-122.4 -67.7 140.9 0.0 -12.1 2.3 237 241 A M + 0 0 0 -12,-2.8 -12,-0.3 -15,-0.2 2,-0.3 -0.682 64.5 130.1 -81.5 90.2 -1.5 -9.7 4.8 238 242 A V + 0 0 29 -2,-1.5 -143,-0.2 1,-0.1 -142,-0.2 -0.970 52.9 26.8-138.0 157.9 -2.1 -12.1 7.7 239 243 A D + 0 0 43 -145,-1.0 2,-0.6 -2,-0.3 -144,-0.2 0.879 64.1 156.3 56.3 46.8 -1.3 -12.1 11.4 240 244 A N + 0 0 0 -146,-1.2 2,-0.4 -3,-0.1 -1,-0.2 -0.312 35.8 114.7 -95.9 50.4 -1.3 -8.2 11.6 241 245 A W - 0 0 40 -2,-0.6 -139,-0.1 -148,-0.1 -138,-0.1 -0.943 62.1-136.2-121.3 143.3 -2.1 -8.4 15.3 242 246 A R - 0 0 4 -2,-0.4 3,-0.1 -141,-0.1 -2,-0.0 -0.802 32.4-119.8 -91.6 135.9 -0.0 -7.2 18.3 243 247 A P - 0 0 56 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.269 43.9 -70.1 -69.4 166.1 -0.1 -9.8 21.3 244 248 A A - 0 0 46 -141,-0.1 -216,-0.3 -216,-0.1 -218,-0.1 -0.244 52.0-149.0 -58.3 141.7 -1.4 -9.0 24.8 245 249 A Q - 0 0 46 -218,-2.8 -216,-0.4 -220,-0.2 -1,-0.1 -0.690 34.0 -72.7-110.4 161.2 0.8 -6.5 26.8 246 250 A P - 0 0 77 0, 0.0 -221,-0.3 0, 0.0 -1,-0.1 -0.275 33.7-148.5 -56.9 133.4 1.3 -6.3 30.6 247 251 A L > + 0 0 59 1,-0.2 3,-1.6 -223,-0.1 2,-0.0 0.815 31.5 172.2 -67.2 -39.0 -1.7 -4.9 32.4 248 252 A K T 3 - 0 0 96 1,-0.3 -1,-0.2 -224,-0.0 -224,-0.1 -0.322 66.9 -10.8 60.1-129.7 0.4 -3.3 35.1 249 253 A N T 3 S+ 0 0 160 -226,-0.3 -1,-0.3 2,-0.1 -2,-0.1 0.802 103.6 124.0 -60.6 -26.6 -1.7 -1.1 37.4 250 254 A R < - 0 0 21 -3,-1.6 2,-0.5 -227,-0.3 -3,-0.0 0.046 47.5-152.9 -77.9 139.6 -4.8 -1.2 35.3 251 255 A Q - 0 0 93 -216,-0.0 2,-0.5 -215,-0.0 -1,-0.1 -0.819 10.6-146.8-100.4 125.1 -8.3 -2.2 36.3 252 256 A I - 0 0 7 -2,-0.5 -216,-2.3 -218,-0.1 2,-0.3 -0.849 18.1-155.5 -86.5 131.7 -10.7 -3.6 33.6 253 257 A K E -cN 36 189B 74 -64,-2.5 -64,-2.6 -2,-0.5 2,-0.4 -0.855 1.6-148.1-108.9 147.6 -14.3 -2.6 34.3 254 258 A A E -cN 37 188B 5 -218,-2.4 -216,-2.6 -2,-0.3 -66,-0.2 -0.917 10.7-153.2-116.7 139.1 -17.4 -4.5 33.1 255 259 A S S S+ 0 0 25 -68,-2.8 2,-0.3 -2,-0.4 -67,-0.1 0.462 77.1 48.6 -85.0 -0.0 -20.7 -2.9 32.2 256 260 A F 0 0 20 -69,-0.3 -2,-0.1 -70,-0.0 -218,-0.1 -0.881 360.0 360.0-140.3 165.5 -22.5 -6.1 33.0 257 261 A K 0 0 196 -2,-0.3 -220,-0.0 -220,-0.1 -3,-0.0 -0.215 360.0 360.0 47.0 360.0 -23.2 -9.1 35.3