==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 28-AUG-02 1MK2 . COMPND 2 MOLECULE: SMAD 3; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR B.Y.QIN,S.S.LAM,J.J.CORREIA,K.LIN . 235 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10961.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 166 70.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 58 24.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 9.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 13.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 40 17.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 2 1 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 1 3 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 219 A D 0 0 164 0, 0.0 234,-2.4 0, 0.0 2,-0.8 0.000 360.0 360.0 360.0 -70.8 19.0 28.9 43.5 2 220 A L E -A 234 0A 85 232,-0.2 230,-0.0 233,-0.1 0, 0.0 -0.862 360.0-174.4-102.6 102.8 20.0 30.4 46.9 3 221 A Q E -A 233 0A 103 230,-1.8 230,-2.2 -2,-0.8 2,-0.2 -0.863 26.0-117.1-101.8 128.8 20.4 34.2 46.4 4 222 A P E -A 232 0A 58 0, 0.0 2,-0.5 0, 0.0 228,-0.3 -0.407 23.5-164.7 -67.2 128.6 21.7 36.3 49.4 5 223 A V E -A 231 0A 9 226,-3.7 226,-2.7 -2,-0.2 2,-0.3 -0.964 11.1-159.5-116.6 117.2 19.4 38.9 50.9 6 224 A T E -A 230 0A 56 -2,-0.5 224,-0.3 224,-0.3 2,-0.2 -0.702 19.9-113.6-101.2 148.6 21.1 41.4 53.2 7 225 A Y - 0 0 8 222,-3.6 2,-0.4 -2,-0.3 176,-0.1 -0.556 31.3-161.0 -75.6 140.4 19.6 43.6 55.9 8 226 A C - 0 0 40 175,-0.3 179,-0.2 -2,-0.2 178,-0.1 -0.978 18.9-123.6-133.8 119.0 19.8 47.2 55.0 9 227 A E - 0 0 146 -2,-0.4 4,-0.1 1,-0.1 3,-0.0 -0.392 32.7-133.6 -57.3 117.8 19.5 50.0 57.6 10 228 A P - 0 0 10 0, 0.0 3,-0.3 0, 0.0 -1,-0.1 -0.172 13.4-119.4 -72.9 167.3 16.6 52.3 56.7 11 229 A A S S+ 0 0 85 1,-0.3 2,-0.8 2,-0.1 -2,-0.0 0.981 114.3 30.8 -67.6 -57.7 16.7 56.1 56.7 12 230 A F S S- 0 0 112 1,-0.1 -1,-0.3 -3,-0.0 20,-0.3 -0.904 81.2-163.0-100.2 107.8 13.9 56.2 59.3 13 231 A W - 0 0 7 -2,-0.8 169,-1.6 18,-0.5 170,-0.8 0.609 64.6 -2.8 -71.2 -13.9 14.4 53.1 61.3 14 232 A C E -BC 31 181B 0 17,-0.9 17,-3.2 167,-0.2 2,-0.4 -0.977 58.5-135.4-168.9 161.3 11.0 53.0 62.9 15 233 A S E -BC 30 180B 17 165,-0.9 165,-1.0 -2,-0.3 2,-0.4 -0.962 19.5-147.3-127.1 145.5 7.7 54.9 63.2 16 234 A I E -BC 29 179B 0 13,-4.3 13,-2.8 -2,-0.4 2,-0.4 -0.942 9.2-169.0-121.3 134.5 5.8 55.5 66.4 17 235 A S E - C 0 178B 9 161,-2.2 161,-2.0 -2,-0.4 2,-0.3 -0.965 14.1-145.5-120.1 135.0 2.1 55.8 67.0 18 236 A Y E -BC 25 177B 0 7,-0.6 7,-2.6 -2,-0.4 2,-0.3 -0.725 17.0-174.7-100.6 148.1 0.6 57.1 70.3 19 237 A Y E -BC 24 176B 43 157,-2.8 157,-2.5 -2,-0.3 2,-0.6 -0.997 24.4-158.3-144.3 147.2 -2.6 55.8 71.9 20 238 A E E > S-B 23 0B 2 3,-2.6 3,-2.1 -2,-0.3 2,-0.3 -0.971 78.6 -51.4-122.6 106.5 -4.8 56.6 74.8 21 239 A L T 3 S- 0 0 51 152,-2.0 152,-0.2 -2,-0.6 151,-0.1 -0.427 121.4 -21.7 61.3-119.6 -6.8 53.4 75.4 22 240 A N T 3 S+ 0 0 124 -2,-0.3 2,-0.5 150,-0.1 -1,-0.3 0.422 119.3 94.3-101.4 1.5 -8.3 52.4 72.1 23 241 A Q E < S-B 20 0B 72 -3,-2.1 -3,-2.6 148,-0.1 2,-0.3 -0.797 73.0-134.9 -95.0 126.4 -8.1 55.8 70.5 24 242 A R E -B 19 0B 77 -2,-0.5 2,-0.4 -5,-0.2 -5,-0.3 -0.655 26.7-159.2 -78.9 141.8 -5.1 56.6 68.4 25 243 A V E -B 18 0B 4 -7,-2.6 -7,-0.6 -2,-0.3 32,-0.1 -0.974 41.7 -7.6-128.6 137.5 -3.8 60.1 69.3 26 244 A G E S- 0 0 31 -2,-0.4 2,-0.2 30,-0.4 26,-0.0 -0.156 90.5 -57.0 76.8-177.0 -1.6 62.5 67.4 27 245 A E E - 0 0 168 1,-0.1 2,-0.5 -10,-0.1 -9,-0.3 -0.509 64.3 -81.1 -96.6 169.4 0.2 61.9 64.2 28 246 A T E - 0 0 53 -2,-0.2 2,-0.5 -11,-0.1 -11,-0.2 -0.582 42.6-146.0 -75.9 119.8 2.7 59.2 63.4 29 247 A F E -B 16 0B 22 -13,-2.8 -13,-4.3 -2,-0.5 2,-0.5 -0.734 9.9-150.2 -86.9 129.0 6.2 60.1 64.6 30 248 A H E -B 15 0B 96 -2,-0.5 2,-0.6 -15,-0.3 -15,-0.2 -0.864 7.3-137.9-106.7 126.4 9.1 58.8 62.4 31 249 A A E +B 14 0B 0 -17,-3.2 -17,-0.9 -2,-0.5 -18,-0.5 -0.687 34.8 156.1 -85.0 122.4 12.5 58.0 63.9 32 250 A S + 0 0 40 15,-0.7 -1,-0.2 -2,-0.6 16,-0.1 0.689 55.4 70.5-111.1 -36.7 15.4 59.2 61.8 33 251 A Q S S- 0 0 77 14,-0.7 3,-0.2 1,-0.1 -20,-0.1 -0.433 79.5-121.6 -90.0 159.7 18.0 59.4 64.5 34 252 A P S S+ 0 0 75 0, 0.0 45,-2.5 0, 0.0 2,-0.4 0.783 98.2 27.2 -62.3 -36.0 20.0 56.8 66.5 35 253 A S E S+G 78 0C 36 43,-0.2 2,-0.2 2,-0.0 43,-0.2 -0.930 74.5 136.0-140.3 116.5 18.9 58.0 70.0 36 254 A M E -G 77 0C 0 41,-2.2 41,-3.6 -2,-0.4 2,-0.3 -0.803 34.2-128.7-142.0-177.3 15.6 59.8 70.8 37 255 A T E -Gh 76 49C 10 11,-0.9 13,-2.8 39,-0.3 2,-0.5 -0.898 6.5-144.4-138.0 163.5 12.9 59.8 73.4 38 256 A V E +Gh 75 50C 0 37,-1.7 37,-1.8 -2,-0.3 13,-0.2 -0.971 41.9 157.4-128.0 107.9 9.1 59.7 73.6 39 257 A D E - h 0 51C 5 11,-0.9 13,-0.7 -2,-0.5 34,-0.2 -0.562 51.3-117.4-121.9-173.7 8.1 61.9 76.5 40 258 A G + 0 0 15 32,-2.3 33,-0.1 11,-0.2 11,-0.1 0.117 61.6 139.1-115.3 20.1 5.1 63.8 77.6 41 259 A F - 0 0 81 31,-0.4 12,-1.3 1,-0.1 2,-0.7 -0.364 59.8-126.9 -69.0 146.3 6.7 67.2 77.6 42 260 A T S S+ 0 0 99 11,-0.3 -1,-0.1 10,-0.2 -2,-0.0 -0.199 74.7 111.7 -84.6 40.9 4.7 70.1 76.3 43 261 A D S S- 0 0 73 -2,-0.7 2,-0.4 1,-0.0 11,-0.3 -0.799 81.9 -92.0-112.0 156.1 7.4 71.0 73.8 44 262 A P - 0 0 90 0, 0.0 8,-0.1 0, 0.0 -2,-0.1 -0.561 47.8-120.4 -71.2 121.8 7.1 70.7 70.0 45 263 A S + 0 0 48 -2,-0.4 2,-0.3 6,-0.2 5,-0.2 -0.018 36.8 177.3 -54.8 165.7 8.4 67.3 68.9 46 264 A N B > -I 49 0C 59 3,-2.6 3,-2.2 -17,-0.0 -1,-0.1 -0.929 50.8 -65.5-158.7 179.2 11.3 67.0 66.5 47 265 A S T 3 S+ 0 0 62 -2,-0.3 -14,-0.7 1,-0.3 -15,-0.7 0.763 134.2 34.8 -41.3 -35.8 13.6 64.6 64.8 48 266 A E T 3 S+ 0 0 44 1,-0.2 -11,-0.9 -16,-0.1 2,-0.3 0.296 119.2 41.7-106.5 4.8 15.0 63.7 68.2 49 267 A R E < -hI 37 46C 65 -3,-2.2 -3,-2.6 -13,-0.2 2,-1.0 -0.852 54.2-159.6-162.5 119.0 12.1 63.9 70.6 50 268 A F E -h 38 0C 10 -13,-2.8 -11,-0.9 -2,-0.3 2,-0.1 -0.760 24.2-166.0-100.5 84.4 8.5 62.8 70.3 51 269 A C E -h 39 0C 2 -2,-1.0 -11,-0.2 -13,-0.2 -6,-0.2 -0.414 16.8-175.5 -73.6 146.5 6.7 64.9 72.9 52 270 A L > + 0 0 1 -13,-0.7 3,-1.9 -2,-0.1 -12,-0.2 0.493 63.4 91.2-119.9 -8.8 3.2 64.0 74.0 53 271 A G T 3 S+ 0 0 19 -12,-1.3 -11,-0.3 1,-0.3 -12,-0.1 0.824 90.5 50.8 -56.6 -31.7 2.3 66.8 76.3 54 272 A L T 3 S+ 0 0 96 -13,-0.7 2,-0.5 -11,-0.3 -1,-0.3 0.435 83.6 110.6 -87.1 -2.6 0.9 68.7 73.3 55 273 A L < - 0 0 34 -3,-1.9 2,-0.3 -30,-0.1 -3,-0.1 -0.621 53.2-157.1 -79.6 126.5 -1.3 65.9 72.0 56 274 A S - 0 0 100 -2,-0.5 -30,-0.4 3,-0.0 2,-0.3 -0.772 14.7-176.7-104.7 148.9 -5.0 66.5 72.4 57 275 A N > - 0 0 22 -2,-0.3 3,-2.8 -32,-0.1 -32,-0.1 -0.893 16.8-154.4-142.2 104.2 -7.7 63.9 72.5 58 276 A V T 3 S+ 0 0 146 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.0 0.750 99.2 48.2 -53.2 -24.4 -11.2 65.4 72.8 59 277 A N T 3 S+ 0 0 114 -3,-0.1 -1,-0.3 2,-0.0 -36,-0.0 0.403 80.2 134.7 -98.1 2.5 -12.3 62.1 74.4 60 278 A R < - 0 0 61 -3,-2.8 2,-0.2 1,-0.1 -3,-0.0 -0.224 41.0-157.4 -51.1 137.3 -9.5 62.1 76.9 61 279 A N > - 0 0 69 1,-0.0 4,-2.2 0, 0.0 5,-0.3 -0.614 32.5 -91.1-112.5 176.0 -10.8 61.3 80.3 62 280 A A H > S+ 0 0 70 1,-0.2 4,-3.1 -2,-0.2 5,-0.2 0.907 123.0 54.1 -54.6 -46.0 -9.4 62.0 83.8 63 281 A A H > S+ 0 0 56 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.927 109.8 46.9 -56.4 -48.7 -7.6 58.7 84.0 64 282 A V H > S+ 0 0 2 2,-0.2 4,-3.2 1,-0.2 5,-0.2 0.984 115.3 43.5 -59.3 -59.9 -5.7 59.3 80.7 65 283 A E H X S+ 0 0 78 -4,-2.2 4,-1.0 1,-0.2 -2,-0.2 0.919 112.2 54.2 -53.6 -46.3 -4.7 62.8 81.5 66 284 A L H >< S+ 0 0 96 -4,-3.1 3,-0.8 -5,-0.3 4,-0.4 0.925 114.2 41.0 -52.6 -48.3 -3.7 61.9 85.1 67 285 A T H >< S+ 0 0 16 -4,-2.4 3,-2.7 1,-0.2 4,-0.5 0.903 105.4 65.8 -65.1 -42.7 -1.4 59.2 83.8 68 286 A R H 3X S+ 0 0 26 -4,-3.2 4,-0.5 1,-0.3 3,-0.5 0.704 93.4 63.5 -53.3 -20.1 -0.2 61.5 80.9 69 287 A R T << S+ 0 0 162 -4,-1.0 -1,-0.3 -3,-0.8 -2,-0.2 0.782 100.2 52.3 -75.6 -25.9 1.3 63.5 83.7 70 288 A H T <4 S+ 0 0 97 -3,-2.7 22,-0.4 -4,-0.4 21,-0.4 0.481 82.0 83.8 -92.4 -2.4 3.6 60.7 84.6 71 289 A I T >4 + 0 0 1 -4,-0.5 3,-1.6 -3,-0.5 21,-0.4 1.000 62.4 147.6 -59.3 -61.8 5.1 59.9 81.3 72 290 A G T 3< S+ 0 0 23 -4,-0.5 -32,-2.3 1,-0.3 -31,-0.4 -0.548 73.4 5.7 71.6-128.0 7.6 62.7 82.0 73 291 A R T 3 S- 0 0 148 -2,-0.3 2,-0.3 1,-0.2 -1,-0.3 0.718 98.7-169.6 -60.9 -21.2 11.1 62.0 80.5 74 292 A G < - 0 0 0 -3,-1.6 16,-3.0 -4,-0.2 15,-1.5 -0.479 36.2 -32.3 72.1-128.4 9.4 59.0 79.0 75 293 A V E -GJ 38 88C 0 -37,-1.8 -37,-1.7 -2,-0.3 2,-0.5 -0.994 48.6-138.1-132.9 135.9 11.6 56.4 77.3 76 294 A R E -GJ 37 87C 83 11,-3.6 11,-4.2 -2,-0.4 2,-0.4 -0.840 21.7-156.9 -95.2 132.1 14.8 56.8 75.4 77 295 A L E -GJ 36 86C 0 -41,-3.6 -41,-2.2 -2,-0.5 2,-0.4 -0.900 8.3-169.7-109.7 137.2 15.0 54.7 72.3 78 296 A Y E -GJ 35 85C 25 7,-2.0 7,-1.7 -2,-0.4 2,-0.4 -0.975 9.3-167.8-128.8 139.2 18.3 53.7 70.7 79 297 A Y E + J 0 84C 24 -45,-2.5 2,-0.3 -2,-0.4 5,-0.2 -0.987 23.5 150.5-122.8 135.9 19.0 52.0 67.4 80 298 A I E > - J 0 83C 30 3,-2.1 3,-3.3 -2,-0.4 144,-0.1 -0.843 69.1 -6.4-167.7 126.3 22.5 50.7 66.7 81 299 A G T 3 S- 0 0 30 1,-0.3 45,-0.1 -2,-0.3 3,-0.1 0.819 128.0 -60.3 54.4 29.9 23.8 47.8 64.6 82 300 A G T 3 S+ 0 0 1 1,-0.3 2,-0.3 44,-0.1 -1,-0.3 0.538 113.0 128.9 74.6 4.8 20.1 47.0 64.0 83 301 A E E < -J 80 0C 1 -3,-3.3 -3,-2.1 42,-0.2 2,-0.5 -0.729 45.3-155.5 -92.3 143.5 19.9 46.6 67.8 84 302 A V E -JK 79 124C 2 40,-2.3 40,-1.9 -2,-0.3 39,-1.5 -0.966 12.1-179.2-129.8 119.8 17.1 48.4 69.6 85 303 A F E -JK 78 122C 2 -7,-1.7 -7,-2.0 -2,-0.5 2,-0.4 -0.728 13.4-155.5-109.8 161.7 17.1 49.4 73.3 86 304 A A E -JK 77 121C 0 35,-1.4 35,-1.1 -2,-0.3 2,-0.6 -0.968 9.4-163.0-138.2 114.3 14.5 51.2 75.3 87 305 A E E -JK 76 120C 33 -11,-4.2 -11,-3.6 -2,-0.4 2,-1.0 -0.903 17.1-137.0-107.3 121.9 15.6 53.1 78.3 88 306 A C E +J 75 0C 0 31,-2.3 30,-1.8 -2,-0.6 31,-0.3 -0.634 33.6 163.9 -73.9 104.0 13.0 54.0 80.9 89 307 A L + 0 0 41 -15,-1.5 -14,-0.2 -2,-1.0 -1,-0.2 0.783 49.3 97.2 -87.5 -34.1 14.0 57.6 81.7 90 308 A S S S- 0 0 2 -16,-3.0 28,-0.3 -3,-0.2 -18,-0.1 0.095 81.4-127.6 -48.5 163.2 10.6 58.2 83.3 91 309 A D S S+ 0 0 129 -21,-0.4 2,-0.4 -20,-0.3 -1,-0.1 0.499 96.4 69.9 -93.8 -8.1 10.0 57.9 87.0 92 310 A S S S- 0 0 24 -22,-0.4 66,-0.3 -21,-0.4 -2,-0.1 -0.919 96.1-108.5-109.6 135.3 7.2 55.5 86.3 93 311 A A - 0 0 14 -2,-0.4 65,-1.5 65,-0.2 2,-0.3 -0.064 29.0-143.0 -56.4 161.0 8.0 52.1 84.9 94 312 A I E -DE 115 157B 0 21,-1.9 21,-3.9 63,-0.2 2,-0.4 -0.894 7.5-140.2-123.7 157.7 7.2 51.3 81.3 95 313 A F E -DE 114 156B 12 61,-2.0 61,-1.6 -2,-0.3 2,-0.4 -0.971 12.9-157.7-125.7 135.9 6.0 48.0 79.9 96 314 A V E -DE 113 155B 0 17,-3.0 17,-2.4 -2,-0.4 2,-0.7 -0.923 16.9-168.1-121.7 137.2 7.0 46.3 76.7 97 315 A Q E + E 0 154B 40 57,-3.1 57,-1.8 -2,-0.4 15,-0.2 -0.864 26.9 162.5-117.3 91.5 5.5 43.7 74.4 98 316 A S > - 0 0 0 -2,-0.7 4,-2.4 13,-0.3 5,-0.2 -0.969 30.7-158.8-114.6 117.3 8.3 42.7 72.1 99 317 A P H > S+ 0 0 27 0, 0.0 4,-1.8 0, 0.0 -1,-0.1 0.869 96.8 56.6 -59.4 -39.3 7.8 39.4 70.1 100 318 A N H > S+ 0 0 0 50,-0.4 4,-1.9 23,-0.2 3,-0.1 0.936 108.3 45.7 -58.6 -50.0 11.6 39.3 69.7 101 319 A C H 4 S+ 0 0 0 22,-0.5 6,-0.4 1,-0.2 5,-0.2 0.954 111.5 50.8 -58.6 -53.2 12.2 39.5 73.5 102 320 A N H < S+ 0 0 9 -4,-2.4 5,-0.4 1,-0.2 -1,-0.2 0.795 105.5 60.6 -55.2 -30.5 9.5 36.8 74.2 103 321 A Q H >< S+ 0 0 80 -4,-1.8 3,-0.7 -5,-0.2 -1,-0.2 0.977 111.9 35.8 -61.8 -62.2 11.3 34.7 71.5 104 322 A R G >< S+ 0 0 41 -4,-1.9 3,-1.0 1,-0.2 2,-0.1 -0.117 112.3 47.3 -73.7-169.6 14.6 34.6 73.4 105 323 A Y G 3 S- 0 0 58 1,-0.3 -1,-0.2 96,-0.0 -3,-0.1 0.376 111.0-116.6 57.4 -14.4 14.1 34.4 77.2 106 324 A G G < + 0 0 60 -3,-0.7 -1,-0.3 -5,-0.2 -3,-0.2 0.703 58.3 164.4 57.3 23.3 11.6 31.7 76.2 107 325 A W < - 0 0 17 -3,-1.0 -1,-0.2 -5,-0.4 3,-0.1 -0.311 47.4 -85.0 -71.2 158.0 8.7 33.7 77.6 108 326 A H > - 0 0 143 1,-0.1 3,-1.6 2,-0.1 2,-0.1 -0.215 59.3 -89.5 -57.3 145.2 5.1 32.9 76.8 109 327 A P T 3 S+ 0 0 79 0, 0.0 -1,-0.1 0, 0.0 -6,-0.0 -0.420 110.6 19.8 -66.6 133.0 4.0 34.5 73.5 110 328 A A T 3 S+ 0 0 62 1,-0.2 -2,-0.1 -2,-0.1 53,-0.1 0.271 86.7 155.5 94.5 -3.1 2.4 38.0 73.9 111 329 A T < - 0 0 27 -3,-1.6 2,-0.5 51,-0.1 -13,-0.3 -0.045 33.2-147.1 -55.7 153.6 4.0 38.6 77.3 112 330 A V - 0 0 13 49,-0.2 -15,-0.2 -15,-0.2 2,-0.2 -0.993 13.8-162.4-125.3 122.7 4.6 42.2 78.5 113 331 A C E -D 96 0B 1 -17,-2.4 -17,-3.0 -2,-0.5 2,-0.4 -0.652 18.0-117.1-104.3 164.0 7.6 42.9 80.6 114 332 A K E -D 95 0B 96 88,-0.5 -19,-0.3 -19,-0.3 -21,-0.0 -0.842 14.7-164.6-103.4 129.4 8.4 45.9 82.8 115 333 A I E -D 94 0B 0 -21,-3.9 -21,-1.9 -2,-0.4 3,-0.1 -0.878 23.5-156.0-111.3 95.5 11.3 48.2 82.2 116 334 A P > - 0 0 29 0, 0.0 3,-1.7 0, 0.0 -28,-0.4 -0.129 33.2 -69.5 -67.3 166.9 11.6 50.1 85.5 117 335 A P T 3 S+ 0 0 54 0, 0.0 -28,-0.2 0, 0.0 -26,-0.1 -0.189 120.4 23.1 -55.2 149.0 13.2 53.5 85.8 118 336 A G T 3 S+ 0 0 45 -30,-1.8 2,-0.2 -28,-0.3 -29,-0.1 0.352 107.9 101.4 76.4 -7.6 17.0 53.7 85.3 119 337 A C < - 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0 0 31 -3,-1.7 4,-1.3 -4,-0.2 -1,-0.4 -0.294 47.9 -45.4 89.7-173.1 8.4 28.6 53.1 141 359 A F H >> S+ 0 0 126 2,-0.2 4,-3.1 1,-0.2 3,-0.8 0.979 127.6 50.2 -61.1 -66.9 6.4 31.9 52.9 142 360 A E H 3> S+ 0 0 162 1,-0.3 4,-1.5 2,-0.2 -1,-0.2 0.883 107.7 56.0 -41.1 -53.2 4.0 31.6 55.8 143 361 A A H 3< S+ 0 0 13 -4,-0.5 4,-0.4 1,-0.2 -1,-0.3 0.903 115.9 38.2 -47.1 -48.2 6.9 30.8 58.2 144 362 A V H X< S+ 0 0 0 -4,-1.3 3,-2.6 -3,-0.8 4,-0.4 0.943 108.1 58.8 -71.6 -50.8 8.6 34.0 57.1 145 363 A Y H >< S+ 0 0 130 -4,-3.1 3,-1.0 1,-0.3 4,-0.3 0.742 97.3 69.6 -52.3 -18.6 5.5 36.2 56.9 146 364 A Q G >< S+ 0 0 99 -4,-1.5 3,-1.2 -5,-0.4 -1,-0.3 0.817 85.6 64.0 -69.5 -31.6 5.1 35.2 60.5 147 365 A L G X S+ 0 0 10 -3,-2.6 3,-1.2 -4,-0.4 4,-0.5 0.592 79.5 82.7 -70.6 -9.5 8.2 37.3 61.6 148 366 A T G X S+ 0 0 32 -3,-1.0 3,-1.7 -4,-0.4 -1,-0.3 0.878 82.3 64.0 -59.9 -35.5 6.4 40.5 60.5 149 367 A R G X S+ 0 0 126 -3,-1.2 3,-1.0 -4,-0.3 -1,-0.3 0.765 94.9 60.8 -57.7 -28.2 4.7 40.4 63.9 150 368 A M G < S+ 0 0 2 -3,-1.2 -50,-0.4 -4,-0.2 -1,-0.3 0.670 91.2 65.3 -74.7 -19.3 8.2 40.8 65.4 151 369 A C G < S+ 0 0 0 -3,-1.7 30,-2.8 -4,-0.5 2,-0.5 0.402 91.7 76.8 -84.6 2.6 8.8 44.1 63.8 152 370 A T E < + F 0 180B 36 -3,-1.0 2,-0.4 28,-0.2 28,-0.2 -0.966 60.0 178.0-117.4 120.8 5.9 45.6 65.8 153 371 A I E - F 0 179B 0 26,-1.3 26,-2.9 -2,-0.5 2,-0.4 -0.965 10.7-157.7-124.6 138.8 6.5 46.5 69.4 154 372 A R E +EF 97 178B 84 -57,-1.8 -57,-3.1 -2,-0.4 2,-0.3 -0.906 10.9 179.5-118.0 145.7 4.1 48.0 71.8 155 373 A M E -EF 96 177B 2 22,-2.4 22,-2.9 -2,-0.4 2,-0.4 -0.999 10.4-160.6-145.4 140.4 4.8 49.9 75.0 156 374 A S E -EF 95 176B 1 -61,-1.6 -61,-2.0 -2,-0.3 20,-0.3 -0.974 18.7-129.1-125.9 137.2 2.7 51.6 77.7 157 375 A F E S-E 94 0B 2 18,-2.6 2,-3.3 -2,-0.4 18,-0.4 -0.544 78.0 -15.2 -83.2 148.1 3.9 54.3 80.2 158 376 A V S S+ 0 0 29 -65,-1.5 2,-0.4 -66,-0.3 -65,-0.2 -0.233 125.1 60.8 62.2 -59.8 3.2 54.0 83.9 159 377 A K - 0 0 93 -2,-3.3 -64,-0.2 16,-0.2 2,-0.2 -0.825 69.7-156.6-104.0 139.6 0.5 51.3 83.7 160 378 A G - 0 0 4 -2,-0.4 7,-0.4 -66,-0.1 2,-0.2 -0.582 4.8-162.0-108.2 172.3 1.1 47.8 82.2 161 379 A W + 0 0 3 -2,-0.2 7,-0.2 5,-0.1 2,-0.2 -0.764 32.4 89.9-139.7-176.4 -1.1 45.1 80.7 162 380 A G S > S- 0 0 11 5,-1.5 3,-1.2 -2,-0.2 7,-0.1 -0.618 78.7 -29.7 117.2-178.8 -1.2 41.4 79.9 163 381 A A T 3 S+ 0 0 75 1,-0.3 -51,-0.2 -2,-0.2 3,-0.1 -0.317 128.3 37.7 -65.9 163.9 -2.2 38.2 81.6 164 382 A E T 3 S+ 0 0 110 1,-0.3 2,-0.3 2,-0.1 -1,-0.3 0.449 109.3 116.9 69.2 -0.7 -1.8 38.2 85.4 165 383 A Y S < S- 0 0 63 -3,-1.2 -1,-0.3 1,-0.1 -4,-0.1 -0.673 74.0-142.9-106.8 157.9 -3.0 41.7 84.7 166 384 A R S S+ 0 0 202 -2,-0.3 2,-0.7 1,-0.2 -1,-0.1 0.944 102.6 53.5 -74.4 -52.3 -6.0 43.8 85.5 167 385 A R S S- 0 0 78 -7,-0.4 -5,-1.5 1,-0.2 -1,-0.2 -0.770 72.3-172.9 -85.8 116.0 -5.8 45.4 82.0 168 386 A Q + 0 0 119 -2,-0.7 2,-0.3 -7,-0.2 -1,-0.2 0.827 62.5 41.5 -82.4 -31.1 -5.8 42.4 79.7 169 387 A T S > S- 0 0 74 -8,-0.1 3,-2.3 1,-0.1 4,-0.1 -0.847 76.6-122.7-121.5 156.1 -5.2 44.3 76.4 170 388 A V G > S+ 0 0 6 -2,-0.3 3,-1.6 1,-0.3 -149,-0.2 0.794 112.4 67.4 -58.1 -29.7 -2.9 47.2 75.3 171 389 A T G 3 S+ 0 0 61 1,-0.3 -1,-0.3 -149,-0.1 -148,-0.1 0.611 94.5 55.9 -68.9 -12.4 -6.1 48.8 74.2 172 390 A S G < S+ 0 0 38 -3,-2.3 -1,-0.3 -151,-0.1 -2,-0.2 0.234 86.3 103.8-102.8 11.6 -7.1 49.1 77.9 173 391 A T S < S- 0 0 0 -3,-1.6 -152,-2.0 -152,-0.2 3,-0.3 -0.800 71.8-132.3-100.2 137.4 -4.0 51.0 78.9 174 392 A P S S+ 0 0 5 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 0.873 89.5 12.3 -47.9 -53.3 -4.0 54.8 79.5 175 393 A C S S+ 0 0 0 -18,-0.4 -18,-2.6 -155,-0.2 2,-0.3 -0.898 77.7 145.6-140.3 109.0 -1.0 55.7 77.4 176 394 A W E -CF 19 156B 13 -157,-2.5 -157,-2.8 -2,-0.4 2,-0.3 -0.830 23.8-154.0-136.1 174.0 0.8 53.5 75.0 177 395 A I E -CF 18 155B 0 -22,-2.9 -22,-2.4 -2,-0.3 2,-0.4 -0.958 7.1-147.3-144.1 161.2 2.7 53.5 71.7 178 396 A E E -CF 17 154B 19 -161,-2.0 -161,-2.2 -2,-0.3 2,-0.3 -0.999 14.6-164.8-132.9 131.1 3.5 51.1 68.9 179 397 A L E -CF 16 153B 0 -26,-2.9 -26,-1.3 -2,-0.4 2,-0.4 -0.739 8.3-149.8-110.4 163.0 6.7 51.2 66.9 180 398 A H E -CF 15 152B 43 -165,-1.0 2,-1.1 -2,-0.3 -165,-0.9 -0.962 12.4-140.6-137.1 115.3 7.5 49.5 63.6 181 399 A L E > -C 14 0B 3 -30,-2.8 4,-2.0 -2,-0.4 -167,-0.2 -0.665 19.1-176.1 -76.9 100.3 11.0 48.4 62.9 182 400 A N H > S+ 0 0 36 -169,-1.6 4,-3.6 -2,-1.1 5,-0.4 0.885 77.5 64.2 -66.1 -40.3 11.4 49.4 59.3 183 401 A G H > S+ 0 0 0 -170,-0.8 4,-2.5 1,-0.2 -175,-0.3 0.956 110.2 37.0 -46.1 -64.0 14.8 47.8 59.0 184 402 A P H > S+ 0 0 3 0, 0.0 4,-2.6 0, 0.0 -1,-0.2 0.879 117.3 52.4 -55.7 -46.1 13.5 44.3 59.7 185 403 A L H X S+ 0 0 45 -4,-2.0 4,-2.5 2,-0.2 -2,-0.2 0.917 110.6 46.1 -60.8 -47.6 10.3 44.9 57.7 186 404 A Q H >X S+ 0 0 79 -4,-3.6 4,-2.5 1,-0.2 3,-0.6 0.991 115.1 48.0 -57.0 -57.8 12.1 46.0 54.6 187 405 A W H 3X S+ 0 0 0 -4,-2.5 4,-1.9 -5,-0.4 -2,-0.2 0.831 111.5 51.0 -50.9 -36.1 14.5 43.1 55.0 188 406 A L H 3X S+ 0 0 0 -4,-2.6 4,-2.1 -5,-0.2 -1,-0.3 0.863 111.3 48.5 -71.7 -34.8 11.5 40.8 55.5 189 407 A D H < S+ 0 0 80 -4,-2.6 3,-1.1 2,-0.3 -2,-0.2 0.994 106.7 46.6 -56.0 -64.7 10.3 39.1 47.2 194 412 A Q H 3< S+ 0 0 57 -4,-2.7 3,-0.3 1,-0.3 -1,-0.2 0.795 117.3 45.3 -47.6 -32.7 13.3 36.9 46.4 195 413 A M H 3< S+ 0 0 17 -4,-2.0 2,-0.8 1,-0.3 -1,-0.3 0.749 113.5 54.3 -80.2 -27.7 11.0 33.9 47.5 196 414 A G << 0 0 56 -4,-2.2 -1,-0.3 -3,-1.1 39,-0.1 -0.717 360.0 360.0-107.8 77.4 8.3 35.5 45.4 197 415 A S 0 0 112 -2,-0.8 -3,-0.0 -3,-0.3 -4,-0.0 -0.955 360.0 360.0-117.7 360.0 10.0 35.8 42.0 198 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 199 671 B S 0 0 138 0, 0.0 2,-0.2 0, 0.0 -93,-0.1 0.000 360.0 360.0 360.0 140.4 15.7 31.8 80.5 200 672 B P - 0 0 23 0, 0.0 8,-0.0 0, 0.0 6,-0.0 -0.510 360.0-100.8 -86.6 153.3 14.9 34.7 82.9 201 673 B N > - 0 0 65 -2,-0.2 3,-2.0 1,-0.2 6,-0.3 -0.572 23.5-141.2 -72.6 127.9 11.6 35.2 84.7 202 674 B P T 3 S+ 0 0 44 0, 0.0 -88,-0.5 0, 0.0 -1,-0.2 0.626 100.7 63.4 -64.8 -12.1 9.5 37.9 82.8 203 675 B N T 3 S+ 0 0 89 1,-0.2 3,-0.1 -90,-0.1 -2,-0.1 0.484 94.3 64.1 -90.3 -5.2 8.4 39.1 86.3 204 676 B N X - 0 0 61 -3,-2.0 3,-2.8 1,-0.2 4,-0.3 -0.823 57.7-175.2-123.3 92.3 12.0 40.1 87.3 205 677 B P G >> S+ 0 0 22 0, 0.0 3,-3.9 0, 0.0 4,-3.5 0.894 84.4 70.2 -49.0 -40.2 13.4 42.9 85.1 206 678 B A G 34 S+ 0 0 98 1,-0.3 -2,-0.0 2,-0.2 -3,-0.0 0.722 93.7 55.7 -49.8 -26.0 16.6 42.4 87.1 207 679 B E G <4 S+ 0 0 100 -3,-2.8 -1,-0.3 -6,-0.3 -4,-0.0 0.463 127.2 15.3 -88.7 -2.2 16.9 39.1 85.3 208 680 B Y T <4 S+ 0 0 17 -3,-3.9 -2,-0.2 -4,-0.3 -1,-0.1 0.482 109.1 75.6-147.2 -8.6 16.7 40.7 81.9 209 681 B C < - 0 0 25 -4,-3.5 2,-0.3 -5,-0.2 -88,-0.2 -0.307 58.2-145.7 -99.6-172.5 17.2 44.5 82.0 210 682 B S B -L 120 0C 28 -90,-1.6 -90,-1.9 -2,-0.1 -3,-0.0 -0.993 27.4-159.1-159.5 149.1 20.3 46.6 82.4 211 683 B T + 0 0 108 -2,-0.3 -1,-0.1 -92,-0.2 -90,-0.1 0.287 69.2 110.6-105.3 1.9 21.6 49.8 83.9 212 684 B I S S- 0 0 85 -92,-0.1 5,-0.1 1,-0.1 -92,-0.1 -0.670 86.9-100.3 -78.9 127.8 24.6 49.7 81.5 213 685 B P > - 0 0 54 0, 0.0 4,-1.3 0, 0.0 5,-0.1 -0.217 28.7-127.4 -49.1 134.0 24.3 52.5 78.9 214 686 B P H > S+ 0 0 0 0, 0.0 4,-2.6 0, 0.0 3,-0.4 0.885 110.3 52.0 -50.9 -45.3 22.9 50.9 75.7 215 687 B L H > S+ 0 0 85 1,-0.2 4,-1.1 2,-0.2 -3,-0.0 0.970 106.2 52.5 -56.1 -56.3 25.7 52.3 73.7 216 688 B Q H > S+ 0 0 124 1,-0.2 4,-1.1 2,-0.2 -1,-0.2 0.742 111.8 49.8 -53.3 -25.7 28.3 50.9 76.1 217 689 B Q H < S+ 0 0 48 -4,-1.3 -1,-0.2 -3,-0.4 -2,-0.2 0.933 101.9 56.8 -79.8 -51.1 26.6 47.5 75.6 218 690 B A H <>S+ 0 0 2 -4,-2.6 5,-2.4 1,-0.2 6,-0.7 0.664 106.3 57.0 -55.3 -16.8 26.5 47.5 71.8 219 691 B Q H ><5S+ 0 0 114 -4,-1.1 2,-3.9 1,-0.2 3,-3.6 0.976 99.4 51.8 -76.3 -70.0 30.3 47.9 72.0 220 692 B A T 3<5S+ 0 0 97 -4,-1.1 -1,-0.2 1,-0.3 -2,-0.1 -0.063 114.4 47.3 -63.0 43.2 31.2 44.9 74.0 221 693 B S T 3 5S- 0 0 62 -2,-3.9 -1,-0.3 -3,-0.4 -2,-0.2 0.218 109.3-118.7-160.4 -1.3 29.3 42.8 71.6 222 694 B G T < 5 + 0 0 31 -3,-3.6 -3,-0.2 -5,-0.1 -2,-0.1 0.928 64.3 141.2 53.7 54.9 30.6 44.2 68.3 223 695 B A S