==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=2-OCT-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 13-APR-10 3MK0 . COMPND 2 MOLECULE: ALKALINE PHOSPHATASE, PLACENTAL TYPE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR B.STEC,A.CHELTSOV,J.L.MILLAN . 481 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 19847.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 315 65.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 50 10.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 26 5.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 5.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 66 13.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 108 22.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 1 3 1 1 1 0 1 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 1 3 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A I 0 0 134 0, 0.0 371,-0.1 0, 0.0 62,-0.0 0.000 360.0 360.0 360.0 138.3 69.5 16.5 31.2 2 2 A I - 0 0 128 369,-0.0 2,-0.3 367,-0.0 5,-0.1 -0.843 360.0-133.9 -96.5 109.7 69.7 19.6 33.4 3 3 A P > - 0 0 24 0, 0.0 3,-1.5 0, 0.0 4,-0.5 -0.489 13.1-139.4 -62.8 119.0 70.8 22.7 31.4 4 4 A V G > S+ 0 0 110 -2,-0.3 3,-2.1 1,-0.3 4,-0.4 0.874 99.1 59.5 -47.5 -47.4 73.4 24.4 33.6 5 5 A E G > S+ 0 0 118 1,-0.3 3,-0.9 2,-0.2 6,-0.3 0.789 99.8 57.5 -55.2 -30.9 72.1 27.9 32.8 6 6 A E G < S+ 0 0 26 -3,-1.5 -1,-0.3 1,-0.2 -2,-0.2 0.551 89.2 74.5 -80.1 -9.0 68.6 27.0 34.2 7 7 A E G < S+ 0 0 123 -3,-2.1 -1,-0.2 -4,-0.5 -2,-0.2 0.677 82.4 80.2 -73.1 -19.2 70.1 26.1 37.6 8 8 A N S X> S- 0 0 71 -3,-0.9 3,-1.8 -4,-0.4 4,-0.7 -0.813 76.2-145.1 -94.3 121.5 70.6 29.8 38.4 9 9 A P H 3> S+ 0 0 83 0, 0.0 4,-3.0 0, 0.0 3,-0.4 0.813 97.5 70.3 -53.9 -32.8 67.4 31.6 39.6 10 10 A D H 3> S+ 0 0 91 1,-0.2 4,-2.9 2,-0.2 5,-0.2 0.785 90.9 59.7 -51.2 -37.1 68.6 34.7 37.7 11 11 A F H <> S+ 0 0 26 -3,-1.8 4,-1.8 -6,-0.3 -1,-0.2 0.946 112.2 37.5 -58.3 -49.4 67.9 32.8 34.4 12 12 A W H X S+ 0 0 109 -4,-0.7 4,-2.5 -3,-0.4 5,-0.2 0.901 116.8 52.0 -70.4 -42.6 64.2 32.5 35.3 13 13 A N H X S+ 0 0 108 -4,-3.0 4,-2.3 1,-0.2 -2,-0.2 0.922 110.9 47.6 -62.3 -42.4 64.0 35.9 37.0 14 14 A R H X S+ 0 0 131 -4,-2.9 4,-2.4 2,-0.2 -1,-0.2 0.912 112.6 48.8 -63.7 -43.0 65.5 37.6 33.9 15 15 A E H X S+ 0 0 86 -4,-1.8 4,-2.5 -5,-0.2 -1,-0.2 0.900 113.5 46.5 -63.2 -43.3 63.2 35.7 31.5 16 16 A A H X S+ 0 0 52 -4,-2.5 4,-3.0 2,-0.2 -1,-0.2 0.883 110.7 51.9 -70.9 -38.9 60.1 36.6 33.6 17 17 A A H X S+ 0 0 59 -4,-2.3 4,-2.2 -5,-0.2 -1,-0.2 0.909 111.6 48.2 -57.9 -43.8 61.2 40.2 33.9 18 18 A E H X S+ 0 0 122 -4,-2.4 4,-2.4 2,-0.2 -2,-0.2 0.903 110.8 51.3 -63.1 -42.8 61.5 40.2 30.0 19 19 A A H X S+ 0 0 60 -4,-2.5 4,-2.6 2,-0.2 -2,-0.2 0.925 110.0 48.7 -60.5 -47.4 58.0 38.6 29.8 20 20 A L H X S+ 0 0 112 -4,-3.0 4,-2.5 2,-0.2 -2,-0.2 0.901 110.1 52.0 -58.4 -43.2 56.5 41.3 32.0 21 21 A G H X S+ 0 0 23 -4,-2.2 4,-1.2 1,-0.2 -2,-0.2 0.948 112.2 45.5 -58.9 -47.8 58.1 44.0 30.0 22 22 A A H X S+ 0 0 58 -4,-2.4 4,-0.9 1,-0.2 3,-0.3 0.889 111.5 52.7 -63.3 -38.9 56.7 42.6 26.8 23 23 A A H >< S+ 0 0 58 -4,-2.6 3,-0.6 1,-0.2 -1,-0.2 0.896 108.3 50.5 -64.2 -41.9 53.3 42.1 28.4 24 24 A K H 3< S+ 0 0 167 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.738 103.8 60.2 -65.9 -25.8 53.2 45.8 29.5 25 25 A K H 3< S+ 0 0 167 -4,-1.2 -1,-0.2 -3,-0.3 -2,-0.2 0.751 78.6 109.8 -78.2 -23.5 54.1 46.9 26.0 26 26 A L << + 0 0 80 -4,-0.9 -3,-0.0 -3,-0.6 -4,-0.0 -0.292 44.2 175.3 -57.0 128.4 51.0 45.4 24.4 27 27 A Q - 0 0 162 -2,-0.0 2,-0.2 0, 0.0 420,-0.1 -0.987 30.4-112.0-135.1 145.7 48.4 47.9 23.2 28 28 A P - 0 0 74 0, 0.0 2,-0.1 0, 0.0 0, 0.0 -0.528 32.5-116.8 -78.4 143.5 45.1 47.5 21.3 29 29 A A - 0 0 33 414,-0.3 418,-0.0 -2,-0.2 319,-0.0 -0.465 13.0-160.5 -69.9 147.9 44.8 48.8 17.8 30 30 A Q S S+ 0 0 161 -2,-0.1 447,-2.5 448,-0.1 2,-0.2 0.372 72.6 81.8 -99.9 -2.2 42.3 51.6 17.0 31 31 A T B S-a 477 0A 33 445,-0.2 -2,-0.1 1,-0.1 414,-0.1 -0.660 80.5-111.2-110.5 158.2 42.5 50.6 13.4 32 32 A A - 0 0 7 445,-2.7 2,-0.5 -2,-0.2 448,-0.5 -0.265 34.0-101.6 -79.8 166.5 40.8 47.9 11.3 33 33 A A - 0 0 1 432,-2.9 317,-0.2 1,-0.2 316,-0.1 -0.811 23.4-169.5 -88.4 128.9 42.4 44.8 9.7 34 34 A K S S+ 0 0 59 315,-2.4 2,-0.3 -2,-0.5 316,-0.2 0.897 78.8 34.5 -76.8 -44.6 43.0 45.1 6.0 35 35 A N E -b 350 0B 9 314,-2.3 316,-2.5 270,-0.2 2,-0.4 -0.821 68.0-158.9-114.8 151.5 43.8 41.4 5.8 36 36 A L E -bc 351 307B 0 270,-2.6 272,-2.7 -2,-0.3 2,-0.4 -0.998 10.0-179.5-129.0 128.5 42.5 38.3 7.7 37 37 A I E -bc 352 308B 0 314,-2.6 316,-2.7 -2,-0.4 2,-0.5 -0.997 7.4-170.3-127.2 126.8 44.2 35.0 8.0 38 38 A I E -bc 353 309B 0 270,-2.5 272,-2.7 -2,-0.4 2,-0.6 -0.983 5.6-164.1-109.3 122.0 42.9 32.0 9.8 39 39 A F E -bc 354 310B 1 314,-3.4 316,-2.7 -2,-0.5 2,-0.6 -0.943 10.8-165.3-100.2 117.2 45.4 29.2 10.3 40 40 A L E -bc 355 311B 0 270,-2.9 272,-2.4 -2,-0.6 2,-0.9 -0.926 11.7-162.9-110.3 114.1 43.5 26.1 11.2 41 41 A G E > -bc 356 312B 0 314,-3.2 3,-1.8 -2,-0.6 316,-0.6 -0.865 25.8-136.3 -91.1 105.3 45.4 23.2 12.7 42 42 A D T 3 S- 0 0 0 270,-1.8 274,-0.9 -2,-0.9 3,-0.1 -0.533 85.7 -2.8 -71.8 116.7 42.9 20.4 12.2 43 43 A G T 3 S+ 0 0 0 -2,-0.5 2,-1.8 315,-0.4 -1,-0.3 0.497 91.0 144.8 86.6 4.6 42.9 18.4 15.4 44 44 A M < + 0 0 4 -3,-1.8 394,-0.3 315,-0.1 -1,-0.2 -0.502 22.7 168.3 -85.1 74.1 45.6 20.5 16.9 45 45 A G > - 0 0 0 -2,-1.8 4,-2.4 392,-0.1 3,-0.4 -0.100 53.3 -83.8 -74.9-177.7 44.6 20.5 20.6 46 46 A V H > S+ 0 0 67 390,-0.5 4,-2.4 1,-0.3 5,-0.2 0.881 129.2 50.7 -60.3 -40.3 46.7 21.7 23.5 47 47 A S H > S+ 0 0 26 1,-0.2 4,-1.9 2,-0.2 -1,-0.3 0.831 109.6 51.5 -70.3 -29.1 48.5 18.4 23.9 48 48 A T H > S+ 0 0 0 -3,-0.4 4,-3.0 2,-0.2 5,-0.2 0.939 109.2 51.3 -68.8 -46.4 49.4 18.4 20.2 49 49 A V H X S+ 0 0 8 -4,-2.4 4,-2.6 2,-0.2 -2,-0.2 0.938 112.7 43.5 -55.0 -53.2 50.8 22.0 20.5 50 50 A T H X S+ 0 0 43 -4,-2.4 4,-2.4 2,-0.2 -1,-0.2 0.928 115.5 48.4 -62.2 -46.4 53.0 21.2 23.4 51 51 A A H X S+ 0 0 0 -4,-1.9 4,-2.5 -5,-0.2 -1,-0.2 0.922 112.8 48.5 -59.0 -46.1 54.2 17.9 21.9 52 52 A A H X S+ 0 0 0 -4,-3.0 4,-2.8 2,-0.2 5,-0.2 0.869 108.5 55.3 -59.3 -39.9 54.9 19.6 18.6 53 53 A R H X S+ 0 0 52 -4,-2.6 4,-2.9 -5,-0.2 -2,-0.2 0.950 109.1 46.4 -58.7 -49.1 56.8 22.4 20.5 54 54 A I H X S+ 0 0 14 -4,-2.4 4,-2.2 1,-0.2 -2,-0.2 0.940 114.3 47.7 -59.1 -48.6 59.1 19.8 22.1 55 55 A L H X S+ 0 0 30 -4,-2.5 4,-1.6 1,-0.2 -1,-0.2 0.918 114.4 45.5 -58.4 -48.0 59.7 18.0 18.8 56 56 A K H X S+ 0 0 7 -4,-2.8 4,-1.4 2,-0.2 -1,-0.2 0.876 109.5 56.1 -65.2 -39.4 60.4 21.2 16.9 57 57 A G H <>S+ 0 0 0 -4,-2.9 5,-1.7 -5,-0.2 3,-0.3 0.912 110.7 44.1 -58.2 -43.4 62.7 22.4 19.7 58 58 A Q H ><5S+ 0 0 41 -4,-2.2 3,-1.6 1,-0.2 -1,-0.2 0.772 102.2 67.0 -74.4 -26.3 64.8 19.3 19.4 59 59 A K H 3<5S+ 0 0 138 -4,-1.6 -1,-0.2 1,-0.3 -2,-0.2 0.878 102.7 48.3 -56.5 -39.0 64.8 19.6 15.6 60 60 A K T 3<5S- 0 0 95 -4,-1.4 -1,-0.3 -3,-0.3 -2,-0.2 -0.036 129.3 -98.4 -94.2 29.8 66.9 22.7 16.0 61 61 A D T < 5S+ 0 0 153 -3,-1.6 -3,-0.2 1,-0.2 2,-0.2 0.816 85.8 122.9 58.0 36.6 69.3 21.0 18.5 62 62 A K S S+ 0 0 0 -7,-0.2 3,-1.7 306,-0.1 -1,-0.1 -0.724 84.8 60.0 129.6 -85.7 62.5 21.0 23.4 65 65 A P T 3 S+ 0 0 56 0, 0.0 -11,-0.1 0, 0.0 -10,-0.1 0.631 98.7 60.0 -67.1 -19.7 59.9 22.6 25.7 66 66 A E T 3 S+ 0 0 61 -12,-0.1 -12,-0.1 2,-0.1 -13,-0.0 0.553 85.3 89.5 -84.5 -10.5 61.7 25.9 26.2 67 67 A I S < S- 0 0 37 -3,-1.7 -10,-0.2 -14,-0.1 2,-0.1 -0.804 78.1-127.1 -94.7 118.6 61.7 26.9 22.5 68 68 A P - 0 0 49 0, 0.0 2,-0.1 0, 0.0 -2,-0.1 -0.408 12.4-134.3 -63.2 136.4 58.7 28.8 21.3 69 69 A L > - 0 0 1 -2,-0.1 4,-0.6 1,-0.1 3,-0.3 -0.412 33.3-105.7 -66.1 159.5 56.7 27.7 18.3 70 70 A A T >4 S+ 0 0 10 1,-0.2 3,-1.3 2,-0.2 4,-0.3 0.933 126.3 52.0 -53.8 -44.2 55.8 30.5 15.8 71 71 A M G >4 S+ 0 0 0 1,-0.2 3,-1.5 2,-0.2 -1,-0.2 0.808 98.7 65.0 -63.6 -27.7 52.3 30.3 17.1 72 72 A D G 34 S+ 0 0 42 -3,-0.3 -1,-0.2 1,-0.3 -2,-0.2 0.696 92.9 63.1 -66.8 -20.3 53.6 30.6 20.8 73 73 A R G << S+ 0 0 154 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.572 74.5 111.4 -83.9 -10.0 54.8 34.1 19.9 74 74 A F < - 0 0 14 -3,-1.5 368,-0.2 -4,-0.3 279,-0.0 -0.470 65.1-144.0 -64.1 131.9 51.2 35.3 19.2 75 75 A P S S+ 0 0 45 0, 0.0 2,-0.5 0, 0.0 367,-0.2 0.816 75.4 61.2 -70.9 -32.6 50.4 37.8 22.1 76 76 A Y E +D 441 0B 45 365,-2.0 365,-2.8 374,-0.0 2,-0.4 -0.864 59.8 178.4-113.1 130.0 46.7 37.0 22.6 77 77 A V E +D 440 0B 79 -2,-0.5 374,-0.5 363,-0.2 2,-0.3 -0.959 3.9 169.7-127.6 141.1 45.3 33.6 23.6 78 78 A A E -D 439 0B 3 361,-2.1 361,-2.4 -2,-0.4 2,-0.4 -0.961 32.9-117.8-138.7 160.1 41.8 32.4 24.3 79 79 A L E -De 438 452B 68 372,-2.7 374,-3.0 -2,-0.3 2,-0.5 -0.869 28.5-148.1 -97.0 138.6 40.2 29.0 24.9 80 80 A S E -De 437 453B 1 357,-3.2 357,-1.6 -2,-0.4 2,-0.6 -0.928 6.3-139.7-111.7 126.5 37.6 28.0 22.4 81 81 A K E - e 0 454B 76 372,-3.1 374,-1.9 -2,-0.5 375,-0.2 -0.747 20.2-174.2 -89.1 118.2 34.6 25.8 23.2 82 82 A T + 0 0 1 -2,-0.6 -1,-0.1 352,-0.4 16,-0.1 0.416 29.5 133.0-101.1 -4.5 34.2 23.4 20.3 83 83 A Y - 0 0 89 351,-0.2 5,-0.2 7,-0.1 2,-0.2 -0.147 50.1-133.7 -49.5 139.0 30.9 21.4 20.9 84 84 A N - 0 0 3 3,-2.3 22,-0.2 20,-0.1 -1,-0.1 -0.483 29.7-104.0 -79.8 167.0 28.6 21.1 18.0 85 85 A V S S+ 0 0 80 20,-2.2 21,-0.2 1,-0.2 -1,-0.1 0.916 120.8 30.6 -59.7 -39.9 24.9 21.9 18.7 86 86 A D S S+ 0 0 79 19,-0.4 2,-0.3 1,-0.1 -1,-0.2 0.607 123.1 41.4 -98.3 -14.3 24.1 18.1 18.7 87 87 A K - 0 0 94 1,-0.1 -3,-2.3 4,-0.0 -1,-0.1 -1.000 58.9-146.7-142.2 137.7 27.4 16.5 19.9 88 88 A H S S+ 0 0 164 -2,-0.3 -1,-0.1 -5,-0.2 -6,-0.1 0.838 98.8 51.7 -68.4 -38.2 29.9 17.3 22.7 89 89 A V S S- 0 0 63 -6,-0.1 -1,-0.2 343,-0.1 345,-0.1 -0.929 92.4-152.6-104.7 112.8 32.8 16.0 20.7 90 90 A P - 0 0 1 0, 0.0 2,-0.2 0, 0.0 342,-0.1 -0.174 10.2-132.2 -88.6 174.0 32.5 17.7 17.3 91 91 A D > - 0 0 3 18,-0.1 4,-1.4 -4,-0.1 5,-0.2 -0.643 33.3-103.7-111.3 177.6 33.5 17.1 13.7 92 92 A X H > S+ 0 0 10 -2,-0.2 4,-1.8 2,-0.2 66,-0.1 0.736 112.7 59.0 -73.5 -28.9 35.3 19.3 11.2 93 93 A G H > S+ 0 0 0 2,-0.2 4,-1.6 1,-0.2 18,-0.5 0.972 111.1 37.1 -64.5 -56.8 32.2 20.3 9.2 94 94 A A H > S+ 0 0 0 1,-0.2 4,-1.4 2,-0.2 11,-0.5 0.784 115.6 53.4 -76.2 -28.2 30.2 21.8 12.0 95 95 A T H X S+ 0 0 0 -4,-1.4 4,-2.7 2,-0.2 5,-0.3 0.912 105.1 55.9 -68.6 -41.7 33.2 23.4 13.7 96 96 A A H X>S+ 0 0 0 -4,-1.8 4,-2.7 1,-0.2 5,-0.7 0.923 103.6 55.1 -50.8 -45.4 34.0 25.1 10.4 97 97 A T H X>S+ 0 0 0 -4,-1.6 4,-1.8 12,-0.3 6,-1.3 0.915 112.0 44.7 -54.8 -43.5 30.5 26.5 10.4 98 98 A A H X5S+ 0 0 0 -4,-1.4 4,-1.2 4,-0.2 361,-0.5 0.970 121.0 34.2 -66.0 -56.8 31.4 28.0 13.9 99 99 A Y H <5S+ 0 0 1 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.654 131.2 33.0 -81.0 -12.8 34.9 29.4 13.2 100 100 A L H <5S+ 0 0 2 -4,-2.7 32,-3.2 -5,-0.3 33,-0.3 0.713 133.5 24.0-108.7 -30.4 34.2 30.4 9.6 101 101 A C H < - 0 0 12 7,-0.3 3,-2.0 -2,-0.2 6,-0.1 -0.702 61.8 -78.6 -94.9 138.9 25.1 19.9 13.7 107 107 A F T 3 S+ 0 0 41 -2,-0.3 11,-0.2 1,-0.2 -1,-0.1 0.029 112.8 9.2 -27.6 124.7 27.8 17.3 13.3 108 108 A Q T 3 S+ 0 0 50 1,-0.3 58,-2.3 -3,-0.1 2,-0.3 0.403 101.5 108.2 75.4 2.5 28.9 16.5 9.7 109 109 A T < - 0 0 0 -3,-2.0 2,-0.4 56,-0.2 -12,-0.3 -0.702 55.0-149.8 -97.0 162.4 27.0 19.4 8.1 110 110 A I B -K 163 0C 0 53,-2.6 53,-2.6 -2,-0.3 -16,-0.1 -0.999 67.0 -2.1-138.9 133.3 28.9 22.5 6.7 111 111 A G S S+ 0 0 0 -18,-0.5 18,-2.5 -2,-0.4 2,-0.4 0.748 102.7 113.2 62.5 26.0 27.9 26.1 6.4 112 112 A L B -L 128 0D 0 16,-0.2 16,-0.2 51,-0.2 -6,-0.2 -0.979 67.0-118.1-131.4 143.3 24.4 25.4 7.8 113 113 A S > - 0 0 26 14,-2.7 3,-1.8 -2,-0.4 -7,-0.3 -0.203 42.1 -98.4 -66.6 168.9 22.6 26.4 11.0 114 114 A A T 3 S+ 0 0 25 -10,-0.7 -1,-0.1 1,-0.3 -9,-0.1 0.368 114.6 80.6 -79.6 7.4 21.5 23.7 13.4 115 115 A A T 3 S+ 0 0 60 12,-0.1 -1,-0.3 9,-0.1 2,-0.1 0.710 82.3 81.7 -78.4 -23.3 18.0 23.8 11.9 116 116 A A S < S- 0 0 0 -3,-1.8 2,-0.4 11,-0.2 8,-0.1 -0.371 76.6-140.4 -72.2 160.6 19.4 21.6 9.1 117 117 A R > - 0 0 120 3,-0.5 3,-1.8 -2,-0.1 6,-0.2 -0.982 25.3 -98.5-126.6 139.0 19.8 17.9 9.6 118 118 A F T 3 S+ 0 0 71 -2,-0.4 47,-0.2 1,-0.3 -9,-0.1 -0.212 104.5 2.1 -52.0 137.3 22.7 15.7 8.5 119 119 A N T 3 S+ 0 0 80 45,-2.6 2,-0.6 -11,-0.2 -1,-0.3 0.653 99.8 115.2 58.3 18.9 22.1 13.8 5.2 120 120 A Q X - 0 0 97 -3,-1.8 3,-2.1 44,-0.2 -3,-0.5 -0.834 42.5-175.4-119.4 92.3 18.6 15.4 4.8 121 121 A a G > S+ 0 0 10 -2,-0.6 3,-1.8 1,-0.3 4,-0.4 0.837 79.5 63.8 -55.4 -37.8 18.9 17.6 1.7 122 122 A N G 3 S+ 0 0 118 1,-0.3 -1,-0.3 2,-0.1 -3,-0.0 0.400 95.0 59.9 -74.3 3.8 15.4 18.9 2.1 123 123 A T G < S+ 0 0 28 -3,-2.1 -1,-0.3 -6,-0.2 -2,-0.2 0.180 86.6 86.2-106.0 12.2 16.4 20.6 5.4 124 124 A T X + 0 0 13 -3,-1.8 3,-2.0 -8,-0.1 4,-0.2 0.950 61.5 86.5 -78.1 -52.6 19.0 22.7 3.6 125 125 A R T 3 S+ 0 0 199 -4,-0.4 0, 0.0 1,-0.3 0, 0.0 -0.259 95.8 18.9 -72.2 133.6 17.3 25.8 2.3 126 126 A G T 3 S+ 0 0 67 -2,-0.1 -1,-0.3 -10,-0.0 -2,-0.1 0.197 110.9 80.1 93.7 -11.0 16.9 28.8 4.6 127 127 A N < + 0 0 32 -3,-2.0 -14,-2.7 -14,-0.1 -11,-0.2 0.377 57.2 124.5-111.6 6.3 19.7 27.4 6.9 128 128 A E B -L 112 0D 72 -16,-0.2 2,-0.5 -4,-0.2 -16,-0.2 -0.438 43.7-161.3 -66.9 132.3 22.7 28.6 4.8 129 129 A V - 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