==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=7-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE (METALLOPROTEASE) 23-AUG-95 1MMB . COMPND 2 MOLECULE: MATRIX METALLOPROTEINASE-8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR W.BODE,F.GRAMS . 158 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8059.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 79 50.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 10.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 2.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 8 5.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 14 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 32 20.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 85 A N 0 0 153 0, 0.0 2,-0.4 0, 0.0 120,-0.1 0.000 360.0 360.0 360.0 105.9 19.0 53.5 69.8 2 86 A P + 0 0 54 0, 0.0 2,-0.3 0, 0.0 81,-0.1 -0.716 360.0 157.9 -84.2 138.6 16.6 56.0 68.2 3 87 A K - 0 0 73 -2,-0.4 2,-0.3 78,-0.1 117,-0.1 -0.909 45.2 -95.6-147.7 163.8 13.6 54.8 66.2 4 88 A W - 0 0 23 115,-0.3 5,-0.0 -2,-0.3 115,-0.0 -0.705 21.5-153.9 -83.3 139.3 10.2 56.1 65.2 5 89 A E S S+ 0 0 166 -2,-0.3 2,-0.3 2,-0.0 -1,-0.1 0.349 78.6 65.9 -96.3 8.6 7.4 55.1 67.6 6 90 A R - 0 0 123 1,-0.1 -2,-0.1 0, 0.0 3,-0.0 -0.888 67.0-153.6-125.6 151.0 4.8 55.4 64.7 7 91 A T S S+ 0 0 75 -2,-0.3 36,-2.9 1,-0.1 2,-0.6 0.672 77.1 66.1-102.8 -26.5 4.6 53.3 61.6 8 92 A N E -a 43 0A 74 34,-0.2 2,-0.4 36,-0.1 36,-0.2 -0.925 69.6-177.1 -96.6 123.1 2.9 55.4 58.9 9 93 A L E -a 44 0A 0 34,-2.8 36,-2.9 -2,-0.6 2,-0.3 -0.959 16.2-141.3-124.7 138.8 5.4 58.2 58.1 10 94 A T E -a 45 0A 37 -2,-0.4 44,-2.3 34,-0.2 43,-0.8 -0.747 15.6-167.6 -97.8 150.3 4.9 61.2 55.8 11 95 A Y E -ab 46 54A 15 34,-1.9 36,-2.2 -2,-0.3 2,-0.4 -0.947 4.8-161.8-135.3 156.5 7.5 62.6 53.5 12 96 A R E - b 0 55A 43 42,-2.3 44,-2.7 -2,-0.3 2,-0.9 -0.988 15.5-145.1-143.0 131.8 7.8 65.8 51.4 13 97 A I E - b 0 56A 14 -2,-0.4 44,-0.2 34,-0.4 42,-0.1 -0.859 19.0-171.1 -95.7 105.7 10.1 66.7 48.5 14 98 A R - 0 0 102 42,-2.6 2,-0.3 -2,-0.9 43,-0.2 0.745 61.5 -10.2 -71.3 -29.8 10.7 70.5 49.1 15 99 A N - 0 0 57 41,-0.5 2,-0.2 2,-0.0 -1,-0.1 -0.919 69.9-119.9-158.3 177.3 12.5 71.3 45.8 16 100 A Y - 0 0 63 -2,-0.3 6,-0.1 41,-0.1 42,-0.1 -0.764 13.4-118.2-128.1 168.7 14.1 69.6 42.9 17 101 A T > - 0 0 7 -2,-0.2 3,-0.6 4,-0.2 8,-0.1 -0.898 21.3-143.2-107.6 135.5 17.3 69.1 40.9 18 102 A P T 3 S+ 0 0 129 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 0.460 91.3 75.0 -71.4 -18.9 17.2 70.4 37.2 19 103 A Q T 3 S+ 0 0 91 2,-0.1 2,-0.3 80,-0.0 78,-0.0 0.780 102.3 39.0 -69.3 -29.0 19.3 67.5 35.9 20 104 A L S < S- 0 0 16 -3,-0.6 -3,-0.1 79,-0.1 79,-0.0 -0.828 94.9-104.5-118.8 156.1 16.3 65.1 36.2 21 105 A S > - 0 0 56 -2,-0.3 4,-1.9 1,-0.1 5,-0.2 -0.293 33.7-110.8 -72.2 163.9 12.7 65.7 35.5 22 106 A E H > S+ 0 0 124 2,-0.2 4,-2.0 1,-0.2 5,-0.2 0.882 121.0 53.4 -62.7 -39.9 10.4 66.2 38.4 23 107 A A H > S+ 0 0 69 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.933 108.4 48.4 -61.3 -44.9 8.8 62.8 37.5 24 108 A E H > S+ 0 0 78 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.856 110.5 51.3 -63.0 -36.7 12.2 61.0 37.6 25 109 A V H X S+ 0 0 0 -4,-1.9 4,-2.2 2,-0.2 -1,-0.2 0.910 111.5 47.7 -67.0 -41.7 13.1 62.5 40.9 26 110 A E H X S+ 0 0 49 -4,-2.0 4,-2.6 2,-0.2 -2,-0.2 0.869 111.5 50.1 -67.3 -34.9 9.8 61.4 42.4 27 111 A R H X S+ 0 0 132 -4,-2.2 4,-2.5 2,-0.2 5,-0.3 0.929 109.9 50.7 -67.4 -47.0 10.2 57.9 41.0 28 112 A A H X S+ 0 0 12 -4,-2.3 4,-1.4 1,-0.2 -2,-0.2 0.934 115.7 42.3 -56.1 -47.7 13.8 57.7 42.5 29 113 A I H X S+ 0 0 0 -4,-2.2 4,-1.5 2,-0.2 -2,-0.2 0.907 113.5 51.0 -66.4 -47.6 12.5 58.7 45.9 30 114 A K H X S+ 0 0 80 -4,-2.6 4,-2.0 1,-0.2 3,-0.5 0.946 111.5 47.1 -55.9 -54.2 9.4 56.6 45.9 31 115 A D H X S+ 0 0 65 -4,-2.5 4,-1.4 1,-0.2 -1,-0.2 0.814 107.6 57.2 -58.6 -33.3 11.3 53.4 44.9 32 116 A A H X S+ 0 0 0 -4,-1.4 4,-0.7 -5,-0.3 -1,-0.2 0.817 107.9 47.1 -69.6 -35.3 13.9 54.0 47.6 33 117 A F H >X S+ 0 0 1 -4,-1.5 4,-1.5 -3,-0.5 3,-0.8 0.911 105.7 59.6 -72.1 -39.6 11.3 54.1 50.3 34 118 A E H 3X S+ 0 0 78 -4,-2.0 4,-1.8 1,-0.2 -2,-0.2 0.840 95.3 64.0 -56.4 -37.3 9.7 50.9 49.0 35 119 A L H 3< S+ 0 0 16 -4,-1.4 -1,-0.2 1,-0.2 110,-0.2 0.909 108.5 40.3 -52.6 -46.0 13.0 49.0 49.5 36 120 A W H X< S+ 0 0 0 -3,-0.8 3,-0.9 -4,-0.7 6,-0.3 0.772 109.6 59.0 -74.7 -32.3 12.6 49.6 53.3 37 121 A S H >< S+ 0 0 27 -4,-1.5 3,-0.8 1,-0.2 -1,-0.2 0.805 97.7 59.3 -65.3 -37.9 8.9 49.0 53.5 38 122 A V T 3< S+ 0 0 119 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.1 0.513 113.5 39.0 -72.8 -0.5 9.1 45.5 52.1 39 123 A A T < S+ 0 0 15 -3,-0.9 -1,-0.2 -5,-0.1 -2,-0.2 0.301 119.9 37.2-130.7 8.4 11.4 44.5 55.0 40 124 A S S < S- 0 0 18 -3,-0.8 114,-0.1 2,-0.2 110,-0.0 -0.869 85.0-103.0-148.1 177.1 9.8 46.4 57.9 41 125 A P S S+ 0 0 55 0, 0.0 2,-0.2 0, 0.0 -4,-0.1 0.416 79.3 118.0 -89.0 7.3 6.4 47.4 59.3 42 126 A L - 0 0 3 -6,-0.3 2,-0.4 -34,-0.1 -2,-0.2 -0.472 44.9-164.9 -80.6 141.5 6.7 51.1 58.0 43 127 A I E -a 8 0A 102 -36,-2.9 -34,-2.8 -2,-0.2 2,-0.5 -0.978 10.0-153.3-122.7 131.8 4.4 52.7 55.5 44 128 A F E -a 9 0A 18 -2,-0.4 2,-0.4 -36,-0.2 -34,-0.2 -0.944 10.2-170.9-111.6 128.2 5.5 55.9 53.8 45 129 A T E -a 10 0A 54 -36,-2.9 -34,-1.9 -2,-0.5 2,-0.4 -0.952 16.9-133.0-125.7 130.4 3.0 58.5 52.4 46 130 A R E -a 11 0A 109 -2,-0.4 2,-0.3 -36,-0.2 -34,-0.2 -0.641 16.4-168.3 -84.0 129.1 3.8 61.6 50.3 47 131 A I - 0 0 46 -36,-2.2 -34,-0.4 -2,-0.4 3,-0.1 -0.878 18.8-146.0-109.9 140.6 2.2 65.0 51.1 48 132 A S S S- 0 0 81 -2,-0.3 2,-0.3 1,-0.2 -1,-0.1 0.696 79.7 -10.3 -77.9 -17.1 2.5 67.8 48.6 49 133 A Q S S+ 0 0 147 2,-0.1 -1,-0.2 -37,-0.0 2,-0.2 -0.982 93.4 65.9-168.1 172.2 2.8 70.4 51.4 50 134 A G S S- 0 0 40 -2,-0.3 2,-0.6 -3,-0.1 -3,-0.1 -0.537 95.3 -32.4 96.7-169.6 2.5 71.0 55.1 51 135 A E - 0 0 162 -2,-0.2 2,-0.2 4,-0.0 -41,-0.1 -0.767 61.5-171.7 -94.2 117.1 4.8 69.5 57.7 52 136 A A - 0 0 11 -2,-0.6 -41,-0.2 1,-0.1 3,-0.2 -0.615 31.8-126.2 -99.1 159.9 6.1 66.0 56.9 53 137 A D S S+ 0 0 33 -43,-0.8 2,-0.6 1,-0.2 -42,-0.2 0.934 104.6 40.6 -69.4 -40.3 8.1 63.7 59.2 54 138 A I E S-b 11 0A 0 -44,-2.3 -42,-2.3 35,-0.1 2,-0.4 -0.900 74.2-166.3-114.1 111.4 10.8 63.4 56.5 55 139 A N E -b 12 0A 15 -2,-0.6 35,-2.5 -44,-0.2 2,-0.4 -0.833 5.8-162.2 -94.8 137.1 11.7 66.5 54.5 56 140 A I E +bc 13 90A 0 -44,-2.7 -42,-2.6 -2,-0.4 -41,-0.5 -0.961 19.1 159.2-119.3 130.9 13.8 65.9 51.4 57 141 A A E - c 0 91A 1 33,-1.8 35,-2.8 -2,-0.4 2,-0.7 -0.997 40.1-128.8-153.9 154.3 15.8 68.8 49.8 58 142 A F E + c 0 92A 10 -2,-0.3 2,-0.3 33,-0.2 35,-0.2 -0.928 40.7 172.3-100.9 109.5 18.6 69.6 47.5 59 143 A Y E - c 0 93A 71 33,-2.1 35,-2.9 -2,-0.7 36,-0.4 -0.842 24.1-136.9-120.8 161.0 20.9 72.2 49.1 60 144 A Q - 0 0 117 -2,-0.3 33,-0.0 2,-0.2 10,-0.0 -0.907 56.6 -49.9-115.3 139.8 24.4 73.8 48.4 61 145 A R S S+ 0 0 133 -2,-0.3 8,-1.9 7,-0.1 2,-0.3 0.029 122.9 22.5 39.2-125.5 27.3 74.5 50.8 62 146 A D + 0 0 137 6,-0.2 -2,-0.2 1,-0.1 8,-0.0 -0.595 69.1 160.4 -69.1 128.6 26.1 76.2 54.0 63 147 A H - 0 0 34 -2,-0.3 -1,-0.1 -4,-0.1 -2,-0.1 -0.061 62.7 -84.6-145.3 32.9 22.4 75.5 54.3 64 148 A G S S+ 0 0 80 1,-0.1 -2,-0.1 0, 0.0 0, 0.0 0.309 105.3 87.3 86.6 -3.3 21.4 76.1 57.9 65 149 A D S S- 0 0 22 2,-0.1 -1,-0.1 21,-0.0 -3,-0.0 0.419 93.0-112.0-112.3 5.2 22.2 72.9 59.7 66 150 A N S S+ 0 0 162 1,-0.0 -4,-0.1 0, 0.0 0, 0.0 0.726 97.1 88.8 73.8 22.1 25.9 73.2 60.7 67 151 A S - 0 0 55 -6,-0.1 -2,-0.1 11,-0.0 -1,-0.0 -0.563 66.6-164.4-149.8 73.6 27.1 70.5 58.3 68 152 A P - 0 0 65 0, 0.0 -6,-0.2 0, 0.0 -7,-0.1 -0.247 17.3-118.2 -65.0 144.6 27.8 72.2 55.0 69 153 A F - 0 0 7 -8,-1.9 7,-0.1 1,-0.1 -9,-0.1 -0.348 15.9-136.4 -77.3 172.3 28.2 70.4 51.7 70 154 A D - 0 0 69 5,-0.5 -1,-0.1 1,-0.4 6,-0.1 0.130 36.0-108.4-123.1 21.4 31.5 70.5 49.8 71 155 A G S S+ 0 0 0 4,-0.1 -1,-0.4 3,-0.0 24,-0.1 -0.371 79.4 5.5 81.7-168.5 30.8 71.1 46.1 72 156 A P S S- 0 0 82 0, 0.0 24,-0.1 0, 0.0 3,-0.1 -0.180 119.4 -13.1 -53.4 142.2 31.3 68.4 43.4 73 157 A N S S+ 0 0 87 1,-0.2 -3,-0.2 22,-0.0 2,-0.2 -0.057 99.6 79.8 58.2-159.5 32.2 64.8 44.6 74 158 A G S S+ 0 0 58 -5,-0.1 2,-0.3 2,-0.0 -1,-0.2 -0.458 101.5 20.2 66.4-135.1 33.3 64.2 48.2 75 159 A I - 0 0 74 -2,-0.2 -5,-0.5 1,-0.1 3,-0.1 -0.562 66.4-173.8 -73.6 125.9 30.2 64.1 50.5 76 160 A L - 0 0 23 -2,-0.3 17,-2.5 1,-0.3 2,-0.3 0.756 57.7 -35.6 -85.9 -31.9 27.1 63.4 48.4 77 161 A A E -D 92 0A 12 15,-0.2 -1,-0.3 -19,-0.0 2,-0.3 -0.944 51.8-146.5-178.7 172.0 24.3 63.8 51.0 78 162 A H E -D 91 0A 34 13,-2.0 13,-2.8 -2,-0.3 2,-0.3 -0.973 4.5-156.7-155.8 161.3 23.4 63.3 54.6 79 163 A A E -D 90 0A 21 -2,-0.3 2,-0.3 11,-0.2 11,-0.2 -0.967 16.0-124.6-144.1 152.5 20.4 62.4 56.8 80 164 A F - 0 0 51 9,-2.2 8,-0.3 -2,-0.3 3,-0.1 -0.771 32.6-104.8-102.4 143.8 19.4 62.8 60.5 81 165 A Q - 0 0 124 -2,-0.3 7,-1.8 1,-0.2 8,-0.2 -0.115 58.9 -63.7 -58.4 162.6 18.3 60.1 62.9 82 166 A P S S+ 0 0 16 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 -0.131 88.7 91.9 -49.5 130.3 14.7 59.5 63.8 83 167 A G - 0 0 30 4,-0.2 2,-0.1 35,-0.1 6,-0.1 -0.966 69.0 -43.4 165.9-179.7 13.2 62.5 65.7 84 168 A Q S > S- 0 0 182 -2,-0.3 3,-2.4 2,-0.1 2,-0.4 -0.336 98.9 -14.8 -72.8 152.5 11.4 65.8 65.9 85 169 A G T 3 S+ 0 0 53 1,-0.3 -2,-0.1 -2,-0.1 4,-0.1 -0.376 144.1 14.0 61.5-113.3 12.0 68.7 63.5 86 170 A I T > S+ 0 0 80 -2,-0.4 3,-2.5 2,-0.1 -6,-0.3 0.721 102.9 117.0 -66.9 -21.3 15.2 68.1 61.6 87 171 A G T < S+ 0 0 7 -3,-2.4 -4,-0.2 1,-0.3 -6,-0.2 -0.161 82.9 10.4 -51.7 132.7 15.0 64.5 62.9 88 172 A G T 3 S+ 0 0 0 -7,-1.8 -1,-0.3 -8,-0.3 30,-0.1 0.195 95.3 138.7 83.3 -15.3 14.6 62.1 60.0 89 173 A D < - 0 0 13 -3,-2.5 -9,-2.2 -8,-0.2 2,-0.4 -0.250 39.2-150.2 -68.1 151.3 15.3 64.7 57.3 90 174 A A E -cD 56 79A 0 -35,-2.5 -33,-1.8 -11,-0.2 2,-0.4 -0.971 8.6-168.0-126.9 124.7 17.5 64.1 54.2 91 175 A H E -cD 57 78A 11 -13,-2.8 -13,-2.0 -2,-0.4 2,-0.4 -0.898 4.3-159.7-114.3 134.9 19.7 66.6 52.3 92 176 A F E -cD 58 77A 0 -35,-2.8 -33,-2.1 -2,-0.4 2,-0.7 -0.893 30.7-109.0-111.3 141.4 21.3 66.1 48.9 93 177 A D E > -c 59 0A 0 -17,-2.5 3,-1.9 -2,-0.4 -33,-0.2 -0.532 23.8-156.7 -69.8 109.6 24.2 68.1 47.6 94 178 A A T 3 S+ 0 0 33 -35,-2.9 -34,-0.2 -2,-0.7 -1,-0.2 0.713 87.4 68.6 -61.1 -17.5 22.7 70.3 44.8 95 179 A E T 3 S+ 0 0 53 -36,-0.4 -1,-0.3 -24,-0.1 2,-0.1 0.570 82.1 93.0 -81.6 -3.8 26.2 70.6 43.3 96 180 A E S < S- 0 0 2 -3,-1.9 2,-0.7 -20,-0.2 9,-0.1 -0.368 84.6-110.6 -84.4 163.7 26.4 66.9 42.2 97 181 A T - 0 0 83 7,-0.1 2,-0.4 -2,-0.1 -2,-0.1 -0.893 37.6-157.4 -93.5 111.9 25.4 65.5 38.9 98 182 A W + 0 0 4 -2,-0.7 2,-0.2 -4,-0.1 8,-0.2 -0.819 19.8 165.8 -97.1 130.9 22.3 63.4 39.6 99 183 A T B -e 106 0B 16 6,-2.7 8,-2.2 -2,-0.4 9,-0.3 -0.776 43.4-142.1-133.3 177.6 21.4 60.7 37.2 100 184 A N S S+ 0 0 85 -2,-0.2 2,-0.1 6,-0.2 6,-0.1 -0.066 82.9 71.5-131.3 31.7 19.2 57.6 36.8 101 185 A T S S- 0 0 71 2,-0.3 -2,-0.1 4,-0.1 4,-0.1 -0.386 105.5 -80.8-124.3-162.4 21.8 55.6 34.9 102 186 A S S S+ 0 0 84 -2,-0.1 4,-0.2 2,-0.1 35,-0.1 0.622 97.4 106.9 -82.9 -9.5 25.1 53.9 35.8 103 187 A A S S- 0 0 49 1,-0.1 2,-0.4 2,-0.1 -2,-0.3 -0.253 86.8 -59.0 -65.7 146.6 26.8 57.3 35.5 104 188 A N S S+ 0 0 97 1,-0.2 -1,-0.1 -6,-0.1 -7,-0.1 -0.513 116.5 24.8 -63.0 116.9 28.0 59.2 38.7 105 189 A Y - 0 0 28 -2,-0.4 -6,-2.7 -6,-0.1 2,-0.6 0.520 62.2-166.2-132.3 138.5 25.7 59.7 40.7 106 190 A N B > -e 99 0B 2 -8,-0.2 4,-1.7 1,-0.2 5,-0.2 -0.602 11.7-156.6 -82.1 114.5 22.6 57.5 40.7 107 191 A L H > S+ 0 0 0 -8,-2.2 4,-3.0 -2,-0.6 5,-0.2 0.875 87.3 57.7 -58.2 -40.4 20.0 59.4 42.8 108 192 A F H > S+ 0 0 26 -9,-0.3 4,-2.8 1,-0.2 -1,-0.2 0.934 109.0 44.3 -58.3 -51.0 18.0 56.2 43.8 109 193 A L H > S+ 0 0 4 2,-0.2 4,-1.5 1,-0.2 -1,-0.2 0.890 115.7 46.8 -64.1 -40.2 20.9 54.4 45.4 110 194 A V H X S+ 0 0 9 -4,-1.7 4,-2.3 2,-0.2 -2,-0.2 0.935 113.8 49.6 -68.7 -40.0 22.1 57.5 47.3 111 195 A A H X S+ 0 0 0 -4,-3.0 4,-2.5 1,-0.2 5,-0.2 0.931 106.6 54.7 -64.2 -41.0 18.5 58.1 48.4 112 196 A A H X S+ 0 0 0 -4,-2.8 4,-0.8 1,-0.2 -1,-0.2 0.850 109.4 49.2 -60.3 -36.1 18.1 54.5 49.6 113 197 A H H X S+ 0 0 26 -4,-1.5 4,-1.1 2,-0.2 3,-0.5 0.919 110.2 49.0 -68.7 -48.6 21.3 55.0 51.8 114 198 A E H >X S+ 0 0 11 -4,-2.3 4,-1.8 1,-0.2 3,-0.8 0.921 105.9 57.1 -59.5 -43.3 20.1 58.2 53.4 115 199 A F H 3X S+ 0 0 0 -4,-2.5 4,-1.4 1,-0.3 -1,-0.2 0.789 97.3 63.0 -60.7 -27.9 16.7 56.7 54.2 116 200 A G H 3<>S+ 0 0 0 -4,-0.8 5,-2.5 -3,-0.5 4,-0.3 0.937 107.1 44.1 -61.7 -41.6 18.4 54.0 56.2 117 201 A H H X<5S+ 0 0 31 -4,-1.1 3,-1.4 -3,-0.8 -2,-0.2 0.884 107.7 56.7 -65.7 -45.4 19.8 56.8 58.5 118 202 A S H 3<5S+ 0 0 0 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.781 109.6 49.6 -54.8 -32.7 16.3 58.6 58.7 119 203 A L T 3<5S- 0 0 0 -4,-1.4 -115,-0.3 -5,-0.2 -1,-0.3 0.511 129.5 -94.0 -86.1 -7.9 15.0 55.2 60.0 120 204 A G T < 5S+ 0 0 11 -3,-1.4 -3,-0.2 1,-0.3 2,-0.2 0.475 76.4 135.1 111.1 -1.4 17.7 54.8 62.6 121 205 A L < - 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