==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=7-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE(ACID PROTEINASE) 19-FEB-92 1MPP . COMPND 2 MOLECULE: PEPSIN; . SOURCE 2 ORGANISM_SCIENTIFIC: RHIZOMUCOR PUSILLUS; . AUTHOR M.NEWMAN,F.WATSON,P.ROYCHOWDHURY,H.JONES,M.BADASSO, . 357 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14328.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 248 69.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 5.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 116 32.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 38 10.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 32 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 26 7.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 4 3 1 3 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 1 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 -1 A G 0 0 73 0, 0.0 160,-2.6 0, 0.0 161,-0.4 0.000 360.0 360.0 360.0 97.6 30.1 4.0 52.4 2 1 A S - 0 0 71 158,-0.2 2,-0.4 159,-0.1 179,-0.2 -0.951 360.0-156.6-130.7 147.4 31.0 5.8 49.1 3 2 A V E -A 180 0A 20 177,-2.7 177,-3.8 -2,-0.3 2,-0.4 -0.990 14.3-168.1-127.3 126.0 31.1 4.8 45.5 4 3 A D E +A 179 0A 80 -2,-0.4 175,-0.2 91,-0.3 173,-0.0 -0.908 8.5 177.6-123.7 150.0 33.1 6.6 42.9 5 4 A T E -A 178 0A 3 173,-2.7 173,-3.1 -2,-0.4 -2,-0.0 -0.999 38.9 -93.2-143.2 150.3 33.4 6.6 39.2 6 5 A P E -A 177 0A 69 0, 0.0 2,-0.5 0, 0.0 171,-0.3 -0.361 32.1-154.0 -62.5 143.0 35.3 8.5 36.5 7 6 A G E -A 176 0A 0 169,-1.7 169,-2.1 161,-0.1 2,-0.4 -0.994 16.4-163.1-119.6 102.5 33.4 11.5 35.2 8 7 A L E -AB 175 17A 42 9,-2.7 9,-2.7 -2,-0.5 2,-0.5 -0.830 11.6-136.4-104.5 138.3 34.6 12.2 31.7 9 8 A Y E - B 0 16A 13 165,-2.0 2,-0.8 -2,-0.4 7,-0.2 -0.744 7.6-148.5 -92.0 130.5 34.1 15.4 29.8 10 9 A D E >> - B 0 15A 4 5,-3.2 5,-1.5 -2,-0.5 4,-1.2 -0.878 11.0-171.9 -93.3 103.8 33.0 15.2 26.1 11 10 A F T 45S+ 0 0 116 -2,-0.8 -1,-0.1 1,-0.2 5,-0.0 0.675 80.3 61.8 -71.9 -17.7 34.6 18.2 24.4 12 11 A D T 45S+ 0 0 110 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.939 122.0 18.4 -76.3 -45.3 32.7 17.6 21.2 13 11AA L T 45S- 0 0 41 -3,-0.2 -2,-0.2 2,-0.1 -1,-0.2 0.486 100.6-125.4-100.4 -2.4 29.1 18.0 22.7 14 12 A E T <5 + 0 0 59 -4,-1.2 2,-0.3 1,-0.2 -3,-0.2 0.928 69.0 125.6 53.8 51.9 30.3 19.9 25.8 15 13 A E E < -B 10 0A 15 -5,-1.5 -5,-3.2 313,-0.1 2,-0.4 -0.925 58.1-121.9-133.2 167.0 28.5 17.3 28.1 16 14 A Y E -B 9 0A 0 218,-0.5 17,-2.5 -2,-0.3 2,-0.3 -0.898 29.0-161.9-117.0 142.6 29.7 15.1 30.9 17 15 A A E -BC 8 32A 0 -9,-2.7 -9,-2.7 -2,-0.4 15,-0.2 -0.898 16.0-160.6-129.3 157.1 29.6 11.3 31.0 18 16 A I E - C 0 31A 0 13,-2.0 13,-3.0 -2,-0.3 2,-0.2 -0.978 22.1-129.3-127.1 139.4 29.7 8.3 33.2 19 17 A P E + C 0 30A 35 0, 0.0 76,-0.3 0, 0.0 2,-0.3 -0.649 35.4 167.0 -84.3 145.2 30.4 4.7 32.2 20 18 A V E - C 0 29A 6 9,-2.3 9,-2.7 -2,-0.2 2,-0.4 -0.945 27.0-139.0-144.9 169.0 27.9 2.1 33.5 21 19 A S E -DC 93 28A 27 72,-2.0 72,-3.3 -2,-0.3 2,-0.4 -0.997 16.6-164.5-133.2 138.2 27.1 -1.6 32.9 22 20 A I E > +DC 92 27A 1 5,-1.9 5,-2.3 -2,-0.4 70,-0.2 -0.955 45.3 13.5-122.7 138.6 23.6 -2.9 32.6 23 21 A G T 5S- 0 0 7 68,-2.0 41,-0.1 -2,-0.4 4,-0.1 -0.179 92.8 -43.0 98.9 176.3 22.4 -6.5 32.8 24 22 A T T 5S+ 0 0 53 1,-0.1 41,-2.4 2,-0.1 42,-0.2 -0.992 135.4 19.8-120.9 104.8 23.7 -10.0 33.7 25 23 A P T 5S- 0 0 104 0, 0.0 -1,-0.1 0, 0.0 -3,-0.1 0.666 121.0 -98.7 -76.6 162.2 26.6 -10.2 32.6 26 24 A G T 5 - 0 0 45 -2,-0.1 2,-0.5 -5,-0.1 -3,-0.2 -0.182 26.5-155.2 -59.1 142.1 27.1 -6.4 32.1 27 25 A Q E < -C 22 0A 34 -5,-2.3 -5,-1.9 -4,-0.1 2,-0.3 -0.935 27.5-132.6-106.7 126.7 26.6 -4.6 28.8 28 26 A D E +C 21 0A 105 -2,-0.5 2,-0.3 -7,-0.2 -7,-0.2 -0.751 33.0 160.8 -92.4 142.5 28.8 -1.4 28.9 29 27 A F E -C 20 0A 5 -9,-2.7 -9,-2.3 -2,-0.3 2,-0.5 -0.927 34.8-132.3-147.5 164.8 27.7 2.1 27.9 30 28 A Y E -C 19 0A 79 -2,-0.3 96,-1.9 94,-0.3 97,-0.9 -0.995 33.0-162.5-111.3 132.4 28.9 5.8 28.5 31 29 A L E -Ce 18 127A 0 -13,-3.0 -13,-2.0 -2,-0.5 2,-0.4 -0.944 25.5-112.5-123.4 146.3 25.9 7.9 29.5 32 30 A L E -Ce 17 128A 6 95,-2.7 97,-3.1 -2,-0.4 2,-0.9 -0.435 35.2-132.5 -67.6 115.8 25.4 11.7 29.5 33 31 A F E - e 0 129A 0 -17,-2.5 2,-0.6 -2,-0.4 -17,-0.3 -0.595 32.8-177.7 -76.0 108.1 25.1 12.5 33.2 34 32 A D E > + e 0 130A 15 95,-2.7 97,-2.4 -2,-0.9 3,-1.2 -0.843 29.1 178.3-116.9 107.0 22.0 14.8 33.4 35 33 A T T 3 S+ 0 0 0 -2,-0.6 172,-0.5 1,-0.3 98,-0.2 0.521 83.9 73.0 -82.6 3.1 20.7 16.4 36.7 36 34 A G T 3 S+ 0 0 12 96,-0.1 2,-0.3 170,-0.1 -1,-0.3 0.419 103.3 28.0 -94.3 2.4 18.1 18.0 34.4 37 35 A S < - 0 0 8 -3,-1.2 95,-2.2 92,-0.2 94,-0.9 -0.913 62.8-142.5-151.2 173.4 16.0 14.7 33.8 38 36 A S + 0 0 1 98,-0.5 2,-0.4 -2,-0.3 92,-0.3 0.553 64.4 92.1-122.5 -10.0 15.3 11.5 35.6 39 37 A D - 0 0 0 97,-0.2 2,-0.6 90,-0.1 92,-0.1 -0.691 56.0-151.4 -95.1 137.6 15.1 8.5 33.3 40 38 A T + 0 0 5 -2,-0.4 65,-2.0 63,-0.3 2,-0.3 -0.862 30.2 165.1 -99.7 113.3 18.3 6.4 32.5 41 39 A W E -fG 105 128A 3 87,-2.0 87,-1.1 -2,-0.6 65,-0.2 -0.958 23.8-167.5-139.5 159.7 18.1 4.9 29.1 42 40 A V E -f 106 0A 1 63,-1.9 65,-1.7 -2,-0.3 2,-0.2 -0.922 38.6 -88.7-137.6 159.5 20.2 3.2 26.5 43 41 A P E -f 107 0A 10 0, 0.0 16,-3.1 0, 0.0 2,-0.3 -0.505 41.7-124.3 -73.2 141.5 19.6 2.3 22.8 44 42 A H B > -n 59 0B 38 63,-2.6 3,-2.6 14,-0.2 16,-0.2 -0.559 26.7-107.4 -86.9 132.2 18.0 -1.0 22.0 45 43 A K T 3 S+ 0 0 120 14,-2.9 3,-0.1 -2,-0.3 -1,-0.1 -0.397 113.2 42.6 -56.6 135.4 19.8 -3.4 19.8 46 44 A G T 3 S+ 0 0 71 1,-0.5 2,-0.3 -2,-0.0 -1,-0.3 0.121 81.0 127.1 110.2 -27.0 17.8 -3.4 16.5 47 45 A a < - 0 0 8 -3,-2.6 -1,-0.5 60,-0.2 2,-0.1 -0.602 54.7-138.8 -73.4 128.4 17.4 0.7 16.6 48 46 A D > > - 0 0 83 60,-0.3 5,-1.9 -2,-0.3 3,-1.4 -0.410 18.9-113.8 -86.4 155.4 18.6 1.9 13.2 49 47 A N G > 5S+ 0 0 112 1,-0.3 3,-1.6 3,-0.2 5,-0.1 0.896 120.5 58.5 -69.7 -22.3 20.8 5.0 12.3 50 47AA S G 3 5S+ 0 0 94 1,-0.3 -1,-0.3 2,-0.1 4,-0.1 0.762 105.4 49.9 -76.8 -11.5 17.6 6.3 10.5 51 48 A E G < 5S- 0 0 81 -3,-1.4 59,-3.1 2,-0.1 -1,-0.3 0.317 132.4 -92.8-100.6 7.4 15.8 6.1 13.9 52 49 A G T < 5S+ 0 0 12 -3,-1.6 2,-1.3 -4,-0.2 -3,-0.2 0.298 90.1 120.2 103.4 -7.1 18.7 7.9 15.7 53 50 A a < + 0 0 11 -5,-1.9 -1,-0.2 1,-0.2 -2,-0.1 -0.664 23.0 154.5 -91.8 89.2 21.0 5.1 16.9 54 51 A V + 0 0 36 -2,-1.3 -1,-0.2 60,-0.3 -5,-0.1 0.441 45.7 86.8 -96.6 3.2 24.2 6.1 15.1 55 52 A G S S- 0 0 24 2,-0.1 3,-0.1 71,-0.1 -6,-0.0 0.145 77.1-122.0 -89.2-157.0 26.6 4.4 17.6 56 53 A K S S+ 0 0 88 1,-0.1 2,-0.5 68,-0.1 -1,-0.0 0.519 81.3 83.3-129.2 -5.8 28.0 1.0 18.1 57 54 A R + 0 0 81 -30,-0.0 2,-0.3 -12,-0.0 -2,-0.1 -0.913 54.0 172.3-105.6 128.1 26.9 -0.1 21.7 58 55 A F - 0 0 58 -2,-0.5 2,-0.5 -16,-0.1 -14,-0.2 -0.944 32.3-119.4-129.2 147.5 23.4 -1.5 22.0 59 56 A F B -n 44 0B 0 -16,-3.1 -14,-2.9 -2,-0.3 -36,-0.1 -0.809 22.2-165.9 -96.5 135.2 21.5 -3.2 24.7 60 57 A D > - 0 0 31 -2,-0.5 3,-1.5 -16,-0.2 4,-0.4 -0.899 8.4-170.5-116.3 102.4 20.4 -6.7 24.1 61 58 A P G > S+ 0 0 19 0, 0.0 3,-1.2 0, 0.0 6,-0.2 0.817 85.5 67.3 -65.4 -24.9 17.8 -7.9 26.6 62 59 A S G 3 S+ 0 0 105 1,-0.3 5,-0.0 3,-0.0 -2,-0.0 0.765 100.7 49.3 -70.0 -17.5 18.1 -11.5 25.2 63 60 A S G < S+ 0 0 69 -3,-1.5 2,-0.6 1,-0.0 -1,-0.3 0.434 96.1 83.8 -97.2 1.9 21.7 -11.6 26.6 64 61 A S X - 0 0 9 -3,-1.2 3,-0.8 -4,-0.4 -41,-0.1 -0.891 57.9-166.1-109.1 122.6 20.7 -10.4 30.1 65 62 A S T 3 S+ 0 0 101 -41,-2.4 -1,-0.1 -2,-0.6 -3,-0.0 0.543 89.1 49.2 -79.9 -7.5 19.5 -13.1 32.5 66 63 A T T 3 S+ 0 0 46 -42,-0.2 -1,-0.2 -41,-0.1 2,-0.2 0.259 82.1 121.3-109.1 5.5 18.1 -10.5 35.0 67 64 A F < + 0 0 48 -3,-0.8 2,-0.4 -6,-0.2 23,-0.2 -0.530 34.9 178.8 -72.7 135.4 16.1 -8.4 32.5 68 65 A K E -H 89 0A 42 21,-1.9 21,-2.9 -2,-0.2 2,-0.1 -0.957 22.5-136.0-139.9 119.3 12.4 -8.1 33.0 69 66 A E E -H 88 0A 121 -2,-0.4 19,-0.2 19,-0.3 2,-0.2 -0.357 17.2-150.5 -68.0 143.9 10.2 -5.9 30.7 70 67 A T E - 0 0 29 17,-1.8 17,-0.0 2,-0.2 -1,-0.0 -0.672 24.2-116.0-104.6 177.7 7.6 -3.7 32.5 71 68 A D E S+ 0 0 166 -2,-0.2 2,-0.4 15,-0.1 17,-0.1 0.027 84.4 102.9-102.5 24.8 4.2 -2.8 30.8 72 69 A Y E - 0 0 72 15,-0.4 15,-2.6 2,-0.0 2,-0.3 -0.895 62.6-142.4-108.7 144.5 5.2 0.9 30.8 73 70 A N E -H 86 0A 75 -2,-0.4 2,-0.6 13,-0.2 13,-0.3 -0.735 9.7-136.0-101.4 146.8 6.4 2.9 27.8 74 71 A L E +H 85 0A 0 11,-1.7 11,-2.2 -2,-0.3 2,-0.4 -0.898 32.2 163.7 -95.6 116.8 9.1 5.6 27.9 75 72 A N E +H 84 0A 65 -2,-0.6 2,-0.5 9,-0.2 9,-0.2 -0.846 18.3 173.5-136.6 89.4 7.9 8.6 25.7 76 73 A I E -H 83 0A 17 7,-2.7 7,-2.6 -2,-0.4 2,-0.4 -0.933 21.3-161.1-109.2 134.3 10.2 11.4 26.8 77 74 A T E -H 82 0A 127 -2,-0.5 5,-0.3 5,-0.2 2,-0.2 -0.881 9.8-171.9-108.7 138.1 10.5 15.0 25.4 78 75 A Y - 0 0 44 3,-4.2 3,-0.2 -2,-0.4 -41,-0.0 -0.660 45.7 -93.7-115.5 179.7 13.6 17.1 26.1 79 76 A G S S+ 0 0 92 1,-0.2 2,-0.5 -2,-0.2 -1,-0.1 0.973 126.4 26.3 -56.8 -48.4 14.2 20.9 25.2 80 77 A T S S- 0 0 105 -3,-0.1 -1,-0.2 31,-0.0 31,-0.1 -0.979 131.5 -27.8-112.3 122.0 15.7 19.6 22.0 81 78 A G - 0 0 25 -2,-0.5 -3,-4.2 -3,-0.2 2,-0.3 -0.072 56.6-141.4 76.4-166.7 14.4 16.1 21.0 82 79 A G E -HI 77 111A 12 29,-0.9 29,-2.7 -5,-0.3 2,-0.3 -0.977 6.1-132.0 179.9-179.6 13.0 13.1 22.6 83 80 A A E -HI 76 110A 0 -7,-2.6 -7,-2.7 -2,-0.3 2,-0.4 -0.968 5.1-148.5-155.1 160.4 13.0 9.4 22.6 84 81 A N E +HI 75 109A 63 25,-1.6 24,-2.4 -2,-0.3 25,-1.4 -0.988 39.0 102.7-134.0 136.8 10.6 6.5 22.6 85 82 A G E -HI 74 107A 7 -11,-2.2 -11,-1.7 -2,-0.4 2,-0.4 -0.842 58.4 -63.7-173.5-141.0 11.0 3.0 24.0 86 83 A I E -HI 73 106A 29 20,-1.8 20,-2.0 -13,-0.3 2,-0.4 -0.977 31.2-125.9-140.8 144.6 10.1 0.7 26.9 87 84 A Y E + I 0 105A 0 -15,-2.6 -17,-1.8 -2,-0.4 -15,-0.4 -0.716 36.3 165.8 -88.6 141.1 10.8 0.7 30.6 88 85 A F E -HI 69 104A 0 16,-2.6 16,-2.8 -2,-0.4 2,-0.4 -0.861 31.6-121.8-139.9 173.6 12.4 -2.6 32.0 89 86 A R E +HI 68 103A 97 -21,-2.9 -21,-1.9 -2,-0.3 2,-0.3 -0.953 43.9 138.7-118.4 140.0 14.1 -3.6 35.3 90 87 A D E - I 0 102A 0 12,-1.7 12,-2.0 -2,-0.4 2,-0.2 -0.928 55.4 -76.1-159.7-177.3 17.6 -5.0 35.4 91 88 A S E - 0 0 12 -2,-0.3 -68,-2.0 10,-0.2 2,-0.4 -0.573 41.0-167.8 -83.6 143.6 20.9 -4.7 37.4 92 89 A I E -DI 22 99A 0 7,-2.3 7,-2.6 -2,-0.2 2,-0.5 -0.997 3.1-159.7-129.4 133.9 22.9 -1.6 36.8 93 90 A T E +DI 21 98A 39 -72,-3.3 -72,-2.0 -2,-0.4 2,-0.4 -0.966 12.4 175.0-119.3 130.4 26.6 -1.3 38.1 94 91 A V E > S- I 0 97A 0 3,-2.0 3,-2.3 -2,-0.5 -74,-0.1 -0.994 74.6 -9.8-132.8 131.9 28.2 2.1 38.5 95 92 A G T 3 S- 0 0 39 -2,-0.4 -91,-0.3 -76,-0.3 -1,-0.1 0.820 130.1 -55.6 50.8 37.7 31.7 2.4 40.1 96 93 A G T 3 S+ 0 0 71 1,-0.2 2,-0.4 -93,-0.1 -1,-0.3 0.428 112.8 113.6 85.3 -13.6 31.5 -1.3 41.1 97 94 A A E < - I 0 94A 10 -3,-2.3 -3,-2.0 2,-0.0 2,-0.7 -0.808 54.9-150.6 -95.8 130.0 28.2 -1.1 43.1 98 95 A T E - I 0 93A 49 -2,-0.4 2,-0.5 -5,-0.2 -5,-0.2 -0.905 3.5-157.5-110.3 124.0 25.3 -3.0 41.5 99 96 A V E - I 0 92A 0 -7,-2.6 -7,-2.3 -2,-0.7 3,-0.5 -0.788 20.0-138.4 -89.8 130.1 21.8 -1.8 42.1 100 97 A K E S+ 0 0 136 -2,-0.5 -9,-0.2 1,-0.2 57,-0.0 -0.722 72.8 1.1 -98.5 142.2 19.3 -4.7 41.5 101 98 A Q E S+ 0 0 81 -2,-0.3 2,-0.2 1,-0.2 -1,-0.2 0.807 79.7 170.6 56.3 40.6 16.0 -4.4 39.7 102 99 A Q E - I 0 90A 2 -12,-2.0 -12,-1.7 -3,-0.5 2,-0.5 -0.547 38.5-117.5 -76.5 134.7 16.5 -0.7 38.8 103 100 A T E + I 0 89A 4 45,-0.5 -63,-0.3 -2,-0.2 2,-0.3 -0.722 51.0 154.9 -78.2 135.1 13.8 0.6 36.4 104 101 A L E - I 0 88A 2 -16,-2.8 -16,-2.6 -2,-0.5 2,-0.3 -0.763 29.0-135.3-141.4 178.5 15.6 1.7 33.2 105 102 A A E -fI 41 87A 0 -65,-2.0 -63,-1.9 -2,-0.3 2,-0.3 -0.937 2.9-149.5-146.3 161.8 14.5 2.0 29.7 106 103 A Y E -fI 42 86A 14 -20,-2.0 -20,-1.8 -2,-0.3 2,-0.4 -0.918 23.1-137.9-118.9 150.0 15.8 1.2 26.2 107 104 A V E -fI 43 85A 0 -65,-1.7 -63,-2.6 -2,-0.3 -22,-0.3 -0.951 19.5-170.1-120.2 144.7 14.9 3.4 23.2 108 105 A D E S+ 0 0 47 -24,-2.4 2,-0.3 -2,-0.4 -60,-0.3 0.305 84.9 22.9-102.2 -10.1 13.8 2.2 19.6 109 106 A N E + I 0 84A 66 -25,-1.4 -25,-1.6 -62,-0.1 2,-0.3 -0.951 66.8 172.8-157.1 141.9 14.0 5.8 18.4 110 107 A V E - I 0 83A 14 -59,-3.1 2,-0.3 -2,-0.3 -27,-0.2 -0.990 9.3-172.5-151.9 148.7 15.7 8.9 19.4 111 108 A S E + I 0 82A 66 -29,-2.7 -29,-0.9 -2,-0.3 3,-0.2 -0.951 48.1 55.8-131.6 153.5 16.3 12.5 18.3 112 110 A G S >> S- 0 0 18 -2,-0.3 4,-1.0 1,-0.2 3,-0.9 -0.843 101.4 -25.7 125.5-172.9 18.5 15.2 19.7 113 111 A P G >4 S+ 0 0 56 0, 0.0 3,-0.8 0, 0.0 4,-0.5 0.842 131.0 53.5 -52.9 -45.6 22.2 15.6 20.6 114 112 A T G 34 S+ 0 0 13 1,-0.3 3,-0.4 -3,-0.2 -60,-0.3 0.758 110.4 50.4 -62.3 -27.5 22.9 11.9 21.1 115 113 A A G <4 S+ 0 0 22 -3,-0.9 -1,-0.3 1,-0.2 -63,-0.1 0.682 108.4 50.5 -83.3 -17.7 21.5 11.4 17.7 116 114 A E S << S+ 0 0 86 -4,-1.0 -1,-0.2 -3,-0.8 -2,-0.2 0.410 82.4 116.5-104.6 12.6 23.6 14.0 16.0 117 115 A Q S S- 0 0 12 -4,-0.5 7,-0.1 -3,-0.4 -3,-0.0 -0.341 74.0-107.8 -65.3 159.2 27.0 12.9 17.4 118 115AA S > - 0 0 58 1,-0.2 3,-2.0 -2,-0.1 -1,-0.1 -0.720 19.0-138.9 -89.5 133.4 29.6 11.7 15.0 119 115BA P T 3 S+ 0 0 89 0, 0.0 -1,-0.2 0, 0.0 5,-0.1 0.618 104.7 58.0 -64.1 -12.9 30.0 7.9 15.3 120 115CA D T 3 S+ 0 0 97 3,-0.0 4,-0.1 -65,-0.0 -65,-0.0 0.451 76.9 126.8 -97.5 5.3 33.8 8.5 15.0 121 115DA S < - 0 0 19 -3,-2.0 3,-0.1 1,-0.1 -4,-0.0 -0.275 69.8-123.2 -59.6 147.9 33.9 10.9 18.1 122 115EA E S S+ 0 0 107 1,-0.2 2,-0.5 2,-0.0 -1,-0.1 0.886 104.7 32.0 -59.9 -37.8 36.5 9.8 20.6 123 115FA L S S- 0 0 28 2,-0.0 2,-0.5 -115,-0.0 -1,-0.2 -0.981 77.0-167.8-124.8 121.6 33.8 9.7 23.2 124 116 A F - 0 0 22 -2,-0.5 2,-0.7 -3,-0.1 -94,-0.3 -0.965 15.0-143.6-113.2 124.0 30.3 8.7 22.1 125 117 A L - 0 0 0 -2,-0.5 -94,-0.2 1,-0.2 -8,-0.1 -0.815 15.1-171.8 -83.3 101.0 27.4 9.2 24.6 126 118 A D - 0 0 4 -96,-1.9 2,-0.2 -2,-0.7 -95,-0.2 0.747 61.2 -32.9 -70.3 -37.7 25.1 6.2 24.0 127 119 A G E S-e 31 0A 0 -97,-0.9 -95,-2.7 -85,-0.1 2,-0.4 -0.876 74.8 -70.5-159.9-153.0 22.2 7.4 26.1 128 120 A I E -eG 32 41A 12 -87,-1.1 -87,-2.0 -2,-0.2 2,-0.6 -0.897 16.5-150.7-128.9 148.8 21.4 9.4 29.3 129 121 A F E -e 33 0A 0 -97,-3.1 -95,-2.7 -2,-0.4 2,-0.4 -0.974 25.9-144.5-112.8 111.2 21.8 8.9 33.0 130 122 A G E +e 34 0A 0 -2,-0.6 20,-0.4 -92,-0.3 21,-0.3 -0.710 28.3 166.5 -83.4 129.0 19.0 10.8 34.8 131 123 A A + 0 0 0 -97,-2.4 -93,-0.2 -94,-0.9 -96,-0.2 0.094 42.4 101.7-131.4 24.6 19.9 12.4 38.2 132 124 A A S S- 0 0 0 -95,-2.2 74,-0.2 -98,-0.3 17,-0.1 -0.185 86.2 -60.5 -92.5-166.6 17.0 14.7 38.8 133 125 A Y > - 0 0 15 72,-1.6 3,-2.2 -98,-0.2 -1,-0.2 -0.400 45.6-113.1 -79.9 153.0 14.1 13.8 41.3 134 126 A P G > S+ 0 0 24 0, 0.0 3,-1.6 0, 0.0 13,-0.3 0.805 112.2 63.3 -55.3 -33.3 11.8 10.7 40.9 135 127 A D G 3 S+ 0 0 64 69,-0.5 70,-0.1 1,-0.3 13,-0.0 0.672 92.7 66.8 -70.3 -10.5 8.7 12.8 40.2 136 128 A N G < S+ 0 0 34 -3,-2.2 -98,-0.5 69,-0.2 -1,-0.3 0.297 74.0 117.1 -91.6 16.5 10.3 14.2 37.1 137 129 A T S <> S- 0 0 5 -3,-1.6 4,-1.2 -99,-0.2 3,-0.2 -0.389 73.7-122.8 -75.8 164.4 10.3 10.9 35.1 138 130 A A H > S+ 0 0 11 1,-0.2 4,-2.3 2,-0.2 5,-0.3 0.825 111.9 66.2 -71.1 -30.3 8.4 10.6 31.8 139 131 A M H >>S+ 0 0 6 1,-0.2 4,-2.8 2,-0.2 6,-0.8 0.925 100.6 50.0 -57.3 -42.9 6.6 7.6 33.5 140 131AA E H >5S+ 0 0 58 -6,-0.2 4,-1.0 4,-0.2 -1,-0.2 0.876 109.9 47.2 -66.2 -37.8 5.1 10.0 35.9 141 131BA A H <5S+ 0 0 93 -4,-1.2 -1,-0.2 1,-0.2 -2,-0.2 0.812 122.4 37.0 -71.3 -30.2 3.8 12.5 33.3 142 131CA E H <5S+ 0 0 92 -4,-2.3 -2,-0.2 3,-0.2 -3,-0.2 0.873 135.7 14.3 -83.2 -45.2 2.3 9.7 31.3 143 131DA Y H <5S- 0 0 84 -4,-2.8 -3,-0.2 2,-0.3 -2,-0.1 0.433 90.9-123.7-111.9 -14.7 1.0 7.2 33.8 144 131EA G S < - 0 0 0 -2,-0.3 4,-2.1 -17,-0.1 3,-0.2 -0.206 33.2 -94.4 -70.6 171.8 16.2 6.8 40.2 150 136 A V H > S+ 0 0 0 -20,-0.4 4,-2.0 1,-0.2 5,-0.2 0.897 123.7 51.2 -58.5 -47.5 19.6 5.2 40.3 151 137 A H H > S+ 0 0 2 -21,-0.3 4,-0.9 1,-0.2 -1,-0.2 0.853 109.8 48.9 -61.7 -37.0 21.0 7.5 43.0 152 138 A V H > S+ 0 0 26 -3,-0.2 4,-2.6 1,-0.2 3,-0.4 0.886 111.3 50.1 -68.1 -40.3 18.1 7.0 45.3 153 139 A N H X S+ 0 0 16 -4,-2.1 4,-3.3 1,-0.2 6,-0.3 0.791 100.7 62.6 -67.8 -31.5 18.4 3.1 44.9 154 140 A L H <>S+ 0 0 0 -4,-2.0 5,-1.7 1,-0.2 6,-1.6 0.870 113.4 37.2 -60.8 -38.8 22.1 3.1 45.7 155 141 A Y H ><5S+ 0 0 107 -4,-0.9 3,-0.9 -3,-0.4 -2,-0.2 0.878 116.4 49.9 -77.3 -45.6 21.0 4.6 49.1 156 142 A K H 3<5S+ 0 0 70 -4,-2.6 -2,-0.2 1,-0.3 -3,-0.2 0.874 113.6 46.8 -67.5 -32.0 17.9 2.6 49.7 157 143 A Q T 3<5S- 0 0 84 -4,-3.3 -1,-0.3 -5,-0.1 -2,-0.2 0.374 115.6-118.2 -89.7 9.3 19.7 -0.7 48.8 158 144 A G T < 5S+ 0 0 57 -3,-0.9 -3,-0.2 -5,-0.2 -4,-0.1 0.727 75.9 128.7 73.9 15.2 22.5 0.3 51.1 159 145 A L S - 0 0 49 -2,-0.3 3,-2.8 1,-0.2 4,-0.4 -0.699 26.1-162.7 -80.0 98.8 36.3 13.8 47.7 185 172 A N G > S+ 0 0 125 -2,-1.2 3,-1.3 1,-0.3 -1,-0.2 0.766 80.5 72.5 -58.2 -20.9 37.8 16.3 50.2 186 173 A T G 3 S+ 0 0 88 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.0 0.830 94.0 50.6 -70.5 -20.6 40.9 16.5 48.4 187 174 A L G < S+ 0 0 7 -3,-2.8 164,-3.0 163,-0.1 2,-0.5 0.547 83.8 115.5 -89.9 -3.0 39.4 18.5 45.6 188 175 A L B < -O 350 0C 34 -3,-1.3 162,-0.2 -4,-0.4 164,-0.1 -0.584 41.6-175.2 -72.4 119.1 37.9 21.1 48.0 189 176 A G S S- 0 0 42 160,-3.2 2,-0.3 -2,-0.5 161,-0.2 0.452 76.5 -20.4 -84.2 -7.5 39.3 24.6 47.6 190 177 A G S S- 0 0 30 159,-0.5 -1,-0.1 161,-0.0 161,-0.1 -0.984 96.9 -47.8-177.9-175.1 37.2 25.6 50.7 191 178 A D - 0 0 147 -2,-0.3 2,-0.4 1,-0.1 -2,-0.1 -0.269 60.3 -99.9 -71.9 164.9 34.2 24.6 52.6 192 179 A I - 0 0 40 156,-0.1 2,-0.4 154,-0.1 156,-0.2 -0.716 31.7-157.5 -82.4 127.8 31.0 23.6 51.0 193 180 A Q E -L 347 0A 89 154,-2.7 154,-2.7 -2,-0.4 2,-0.3 -0.982 14.8-150.4-110.0 130.6 28.3 26.3 51.1 194 181 A Y E -L 346 0A 52 -2,-0.4 91,-2.9 152,-0.2 2,-0.3 -0.712 17.8-174.9-106.7 149.6 24.6 25.1 50.8 195 182 A T E -L 345 0A 0 150,-2.4 150,-2.6 -2,-0.3 2,-0.3 -0.871 33.8-108.3-125.8 155.3 21.4 26.5 49.4 196 183 A D E -L 344 0A 59 87,-0.4 148,-0.3 -2,-0.3 2,-0.2 -0.688 30.6-115.4 -87.4 145.4 18.0 24.7 49.7 197 184 A V - 0 0 7 146,-2.6 2,-0.4 -2,-0.3 12,-0.2 -0.586 30.2-130.5 -76.7 145.6 16.3 23.2 46.7 198 185 A L E -P 208 0D 56 10,-2.4 10,-0.5 -2,-0.2 8,-0.2 -0.862 13.0-130.9 -98.1 141.1 13.2 24.8 45.8 199 186 A K E - 0 0 130 -2,-0.4 2,-0.3 5,-0.1 5,-0.2 -0.317 19.6-162.3 -76.3 160.1 9.9 22.9 45.1 200 186AA S E > +P 203 0D 31 3,-2.8 3,-2.2 1,-0.1 6,-0.0 -0.943 68.0 1.6-143.4 139.8 7.9 23.6 41.9 201 186BA R T 3 S- 0 0 184 -2,-0.3 -1,-0.1 1,-0.3 3,-0.1 0.866 135.6 -48.7 51.0 44.4 4.2 22.6 41.3 202 186CA G T 3 S+ 0 0 77 1,-0.1 -1,-0.3 -3,-0.1 2,-0.2 0.342 122.4 27.9 85.1 -15.6 3.9 21.1 44.7 203 186DA G E < S-P 200 0D 13 -3,-2.2 -3,-2.8 -5,-0.1 2,-0.6 -0.748 93.2 -51.9-158.0-157.8 7.0 19.0 44.9 204 187 A Y E + 0 0 60 -2,-0.2 -69,-0.5 -5,-0.2 -68,-0.1 -0.893 56.9 138.1-100.8 115.0 10.6 18.1 43.9 205 188 A F E + 0 0 21 -2,-0.6 -72,-1.6 1,-0.4 -69,-0.2 0.670 65.7 14.8-116.8 -64.6 11.2 18.0 40.2 206 189 A F E S- 0 0 57 -8,-0.2 2,-1.4 -74,-0.2 -1,-0.4 -0.554 81.9 -99.8-109.3 172.4 14.6 19.7 39.3 207 190 A W E + 0 0 0 -172,-0.5 25,-2.7 25,-0.3 2,-0.4 -0.738 56.4 175.0 -92.6 84.0 17.5 20.8 41.3 208 191 A D E -PQ 198 231D 11 -2,-1.4 -10,-2.4 -10,-0.5 23,-0.2 -0.863 14.4-158.1 -92.0 119.2 16.3 24.5 41.4 209 192 A A E - Q 0 230D 0 21,-2.9 21,-2.2 -2,-0.4 2,-1.0 -0.756 21.5-116.7-102.7 153.7 18.4 26.8 43.6 210 193 A P E - Q 0 229D 4 0, 0.0 73,-2.4 0, 0.0 2,-0.5 -0.722 32.2-169.9 -88.5 108.8 17.0 30.1 44.9 211 194 A V E -RQ 282 228D 0 17,-2.5 17,-2.5 -2,-1.0 71,-0.3 -0.830 12.4-175.3 -97.6 128.9 19.1 32.9 43.4 212 195 A T E - 0 0 36 69,-3.3 12,-2.4 -2,-0.5 2,-0.3 0.667 61.8 -41.2 -94.4 -21.6 18.4 36.4 45.0 213 196 A G E -RQ 281 223D 5 68,-1.4 68,-2.7 10,-0.2 2,-0.4 -0.989 52.3-102.2 179.2-177.2 20.6 38.5 42.6 214 197 A V E -RQ 280 222D 0 8,-2.4 7,-2.8 -2,-0.3 8,-2.0 -0.994 27.4-159.6-131.9 132.6 23.9 38.7 40.6 215 198 A K E -RQ 279 220D 46 64,-2.3 64,-2.0 -2,-0.4 2,-0.6 -0.968 6.8-157.6-113.7 135.3 26.9 40.9 41.7 216 199 A I E > S-RQ 278 219D 14 3,-2.8 3,-1.5 -2,-0.4 62,-0.2 -0.972 85.0 -21.3-111.9 111.5 29.7 42.1 39.5 217 200 A D T 3 S- 0 0 70 60,-1.6 -1,-0.2 -2,-0.6 61,-0.1 0.861 129.2 -49.8 58.6 43.2 32.8 42.9 41.7 218 201 A G T 3 S+ 0 0 59 1,-0.2 2,-0.4 59,-0.2 -1,-0.3 0.259 116.8 110.2 85.9 -19.8 30.6 43.3 44.9 219 202 A S E < S-Q 216 0D 64 -3,-1.5 -3,-2.8 1,-0.0 2,-0.4 -0.800 75.6-112.0 -99.4 138.6 28.1 45.6 43.3 220 203 A D E +Q 215 0D 114 -2,-0.4 -5,-0.3 -5,-0.2 3,-0.1 -0.531 39.7 165.8 -65.0 114.8 24.5 44.5 42.5 221 204 A A E S+ 0 0 27 -7,-2.8 2,-0.3 -2,-0.4 -6,-0.2 0.606 75.2 20.4-103.7 -21.3 23.9 44.3 38.8 222 205 A V E +Q 214 0D 10 -8,-2.0 -8,-2.4 27,-0.0 2,-0.4 -0.983 63.7 179.8-145.4 133.2 20.7 42.2 39.2 223 205AA S E -Q 213 0D 80 -2,-0.3 -10,-0.2 -10,-0.3 2,-0.2 -0.972 14.2-153.5-136.2 122.4 18.3 41.9 42.2 224 206 A F E - 0 0 53 -12,-2.4 2,-1.0 -2,-0.4 3,-0.1 -0.565 21.9-122.4 -92.1 156.6 15.2 39.7 42.1 225 207 A D E S- 0 0 112 -2,-0.2 -12,-0.0 2,-0.1 -2,-0.0 -0.893 93.3 -6.8 -93.4 100.8 12.2 40.5 44.4 226 208 A G E S- 0 0 58 -2,-1.0 2,-0.1 -14,-0.1 -2,-0.1 0.003 113.7 -54.6 91.4 148.6 12.1 37.2 46.1 227 209 A A E - 0 0 40 -17,-0.1 2,-0.5 -3,-0.1 -15,-0.2 -0.454 49.0-147.5 -70.4 140.6 14.3 34.3 45.0 228 210 A Q E -Q 211 0D 66 -17,-2.5 -17,-2.5 -2,-0.1 2,-0.5 -0.925 23.2-116.5-107.9 133.8 14.1 33.2 41.3 229 211 A A E -Q 210 0D 32 -2,-0.5 2,-0.5 -19,-0.2 95,-0.3 -0.547 28.2-170.5 -68.6 122.9 14.6 29.5 40.7 230 212 A F E -Q 209 0D 1 -21,-2.2 -21,-2.9 -2,-0.5 2,-0.6 -0.975 22.2-133.0-111.5 120.3 17.8 28.8 38.6 231 213 A T E -Qs 208 325D 25 93,-2.7 95,-2.2 -2,-0.5 2,-1.0 -0.590 9.7-140.2 -77.4 119.1 17.8 25.0 37.4 232 214 A I E + s 0 326D 2 -25,-2.7 2,-0.5 -2,-0.6 -25,-0.3 -0.642 33.0 176.8 -78.6 103.3 21.3 23.4 38.1 233 215 A D E > + s 0 327D 17 93,-2.3 3,-1.6 -2,-1.0 95,-0.6 -0.775 28.3 179.9-123.6 97.0 21.6 21.4 34.9 234 216 A T T 3 S+ 0 0 0 -2,-0.5 -218,-0.5 1,-0.3 94,-0.2 0.698 84.8 65.3 -64.7 -18.1 24.8 19.3 34.1 235 217 A G T 3 S+ 0 0 14 -220,-0.1 2,-0.4 -203,-0.1 -1,-0.3 0.415 93.1 66.5 -90.6 6.4 23.1 18.2 30.9 236 218 A T < - 0 0 31 -3,-1.6 92,-2.9 90,-0.2 93,-0.2 -0.973 66.6-159.1-118.9 145.8 23.0 21.7 29.3 237 219 A N + 0 0 38 -2,-0.4 92,-2.4 90,-0.3 93,-0.5 0.947 67.4 60.2 -87.4 -55.3 26.3 23.4 28.4 238 220 A F S S- 0 0 39 90,-0.1 2,-0.9 91,-0.1 89,-0.6 -0.086 85.6-112.4 -76.2 166.7 25.5 27.1 28.3 239 221 A F E -tU 316 326D 0 76,-2.1 78,-2.7 87,-0.2 2,-0.3 -0.853 41.8-157.6 -95.2 102.1 24.1 29.3 31.0 240 222 A I E +tU 317 325D 38 85,-2.6 85,-2.3 -2,-0.9 76,-0.1 -0.683 23.7 148.9 -89.3 133.4 20.5 30.1 29.7 241 223 A A E -t 318 0D 0 76,-2.1 78,-3.0 -2,-0.3 83,-0.2 -0.981 51.2 -77.9-160.3 158.2 18.6 33.1 30.8 242 224 A P E >> -t 319 0D 20 0, 0.0 4,-1.9 0, 0.0 3,-0.8 -0.303 46.8-117.2 -60.8 138.6 15.9 35.7 29.6 243 225 A S H 3> S+ 0 0 63 76,-2.7 4,-2.6 1,-0.2 5,-0.3 0.883 113.6 61.8 -50.2 -28.7 17.5 38.3 27.4 244 226 A S H 3> S+ 0 0 80 75,-0.3 4,-1.4 1,-0.2 -1,-0.2 0.962 105.3 44.7 -70.3 -35.4 16.6 41.0 29.9 245 227 A F H <> S+ 0 0 5 -3,-0.8 4,-1.6 2,-0.2 -1,-0.2 0.911 113.0 52.7 -66.0 -44.3 18.8 39.4 32.6 246 228 A A H X S+ 0 0 0 -4,-1.9 4,-2.9 1,-0.2 5,-0.2 0.916 107.3 51.6 -58.8 -43.1 21.7 38.8 30.1 247 229 A E H X S+ 0 0 82 -4,-2.6 4,-3.1 1,-0.2 5,-0.3 0.931 108.1 52.9 -58.1 -44.0 21.6 42.5 29.0 248 230 A K H X S+ 0 0 119 -4,-1.4 4,-1.3 -5,-0.3 -1,-0.2 0.898 111.4 43.4 -61.3 -39.6 21.9 43.6 32.6 249 231 A V H X S+ 0 0 0 -4,-1.6 4,-2.7 2,-0.2 5,-0.4 0.924 113.0 51.6 -73.5 -41.5 24.8 41.6 33.3 250 232 A V H X S+ 0 0 7 -4,-2.9 4,-2.7 2,-0.2 7,-0.2 0.938 105.6 55.9 -62.5 -40.1 26.5 42.4 30.2 251 233 A K H < S+ 0 0 62 -4,-3.1 -1,-0.2 1,-0.2 -2,-0.2 0.913 115.4 39.0 -57.8 -41.1 26.0 46.2 30.7 252 234 A A H < S+ 0 0 50 -4,-1.3 -1,-0.2 -5,-0.3 -2,-0.2 0.890 129.8 25.1 -83.6 -28.0 27.7 45.9 34.0 253 235 A A H < S+ 0 0 8 -4,-2.7 -3,-0.2 1,-0.2 -2,-0.2 0.680 133.1 22.8-109.4 -23.1 30.6 43.4 33.2 254 235AA L >< + 0 0 1 -4,-2.7 3,-2.5 -5,-0.4 -1,-0.2 -0.456 64.7 167.3-142.1 65.7 31.3 43.6 29.5 255 235BA P T 3 S+ 0 0 98 0, 0.0 -4,-0.1 0, 0.0 -1,-0.1 0.790 77.6 54.1 -53.3 -30.0 30.0 47.1 28.4 256 236 A D T 3 S+ 0 0 54 -6,-0.1 9,-0.1 -3,-0.1 -5,-0.1 0.436 78.9 128.4 -92.4 12.3 31.8 46.8 25.1 257 237 A A < - 0 0 20 -3,-2.5 2,-0.5 -7,-0.2 9,-0.2 -0.359 57.0-128.4 -64.0 151.2 30.3 43.5 24.1 258 238 A T E -W 265 0E 94 7,-2.6 7,-1.8 0, 0.0 2,-0.3 -0.848 22.4-139.5 -99.5 131.0 28.7 43.2 20.6 259 239 A E E +W 264 0E 124 -2,-0.5 2,-0.3 5,-0.2 5,-0.2 -0.665 28.5 161.0 -94.3 138.2 25.1 41.8 20.6 260 240 A S E > -W 263 0E 49 3,-1.4 3,-1.8 -2,-0.3 0, 0.0 -0.897 57.5 -97.9-142.6 171.0 23.8 39.3 18.0 261 241 A Q T 3 S+ 0 0 195 1,-0.3 -1,-0.1 -2,-0.3 3,-0.1 0.891 125.0 59.2 -60.7 -34.1 20.9 36.9 17.7 262 243 A Q T 3 S- 0 0 63 1,-0.1 -1,-0.3 -3,-0.1 2,-0.3 0.236 119.3 -94.1 -71.5 -6.0 23.6 34.4 18.7 263 244 A G E < -W 260 0E 0 -3,-1.8 -3,-1.4 54,-0.1 2,-0.4 -0.866 59.4 -40.6 119.4-162.4 24.6 35.9 22.1 264 245 A Y E -W 259 0E 4 50,-0.4 50,-2.9 52,-0.3 2,-0.3 -0.966 48.3-171.2-118.1 138.2 27.4 38.4 23.1 265 246 A T E +WX 258 313E 34 -7,-1.8 -7,-2.6 -2,-0.4 48,-0.2 -0.828 7.9 175.5-122.5 158.2 31.0 38.5 21.9 266 247 A V E - X 0 312E 4 46,-1.9 46,-3.4 -2,-0.3 2,-0.2 -0.930 47.7 -88.2-145.9 157.1 34.1 40.5 22.9 267 248 A P E >> - X 0 311E 59 0, 0.0 3,-1.4 0, 0.0 4,-0.7 -0.588 40.1-130.8 -68.7 137.3 37.7 40.2 21.6 268 249 A b H 3> S+ 0 0 24 42,-2.4 4,-1.1 1,-0.2 3,-0.4 0.793 100.3 61.0 -59.4 -27.5 39.3 37.5 23.8 269 250 A S H 34 S+ 0 0 102 41,-0.5 4,-0.4 1,-0.2 -1,-0.2 0.799 91.6 67.6 -74.6 -17.0 42.4 39.6 24.6 270 251 A K H <4 S+ 0 0 130 -3,-1.4 -1,-0.2 1,-0.2 -2,-0.2 0.882 116.0 22.7 -65.2 -38.5 40.5 42.4 26.3 271 252 A Y H >< S+ 0 0 26 -4,-0.7 3,-2.5 -3,-0.4 -1,-0.2 0.526 88.3 111.2-107.7 0.5 39.3 40.3 29.2 272 253 A Q T 3< S+ 0 0 74 -4,-1.1 -1,-0.1 1,-0.3 -2,-0.1 0.794 94.8 27.5 -38.7 -52.0 42.1 37.5 29.1 273 254 A D T 3 S+ 0 0 100 -4,-0.4 -1,-0.3 -3,-0.1 -2,-0.1 0.092 90.2 146.2-102.6 22.8 43.6 38.8 32.4 274 255 A S < - 0 0 29 -3,-2.5 25,-0.3 1,-0.1 -3,-0.1 -0.181 34.7-165.8 -60.4 141.7 40.4 40.3 33.8 275 255AA K + 0 0 88 22,-0.1 2,-0.2 23,-0.1 -1,-0.1 0.462 49.4 123.9-109.8 8.4 40.1 40.1 37.6 276 256 A T - 0 0 49 -5,-0.1 22,-3.7 21,-0.1 23,-0.4 -0.341 49.7-150.5 -68.9 134.1 36.4 41.0 37.5 277 257 A T E - V 0 297D 48 20,-0.3 -60,-1.6 -2,-0.2 2,-0.4 -0.787 11.2-148.5-114.9 148.4 34.3 38.5 39.1 278 258 A F E -RV 216 296D 0 18,-3.0 18,-2.7 -2,-0.4 2,-0.5 -0.966 19.2-166.2-111.7 127.5 30.7 37.3 38.5 279 259 A S E -RV 215 295D 5 -64,-2.0 -64,-2.3 -2,-0.4 2,-0.5 -0.996 15.4-152.7-126.9 124.5 28.8 36.2 41.7 280 260 A L E -RV 214 294D 2 14,-2.6 14,-3.0 -2,-0.5 2,-0.6 -0.849 21.1-146.8 -87.5 129.7 25.6 34.3 41.7 281 261 A V E +RV 213 293D 6 -68,-2.7 -69,-3.3 -2,-0.5 -68,-1.4 -0.947 22.1 179.5-110.3 114.5 23.9 35.2 45.1 282 262 A L E -RV 211 292D 2 10,-2.2 10,-2.1 -2,-0.6 -71,-0.2 -0.809 34.9-101.2-110.1 150.1 21.9 32.4 46.5 283 263 A Q E - V 0 291D 55 -73,-2.4 -87,-0.4 -2,-0.3 8,-0.3 -0.472 44.8-113.3 -69.5 146.0 19.9 32.1 49.8 284 263AA K > - 0 0 95 6,-2.9 3,-1.5 -2,-0.2 -89,-0.3 -0.527 38.9 -94.9 -77.3 141.9 21.8 30.2 52.4 285 263BA S T 3 S+ 0 0 33 -91,-2.9 -1,-0.1 1,-0.3 -91,-0.1 -0.266 110.2 11.6 -57.2 129.1 20.3 26.8 53.4 286 263CA G T 3 S+ 0 0 71 1,-0.2 2,-0.4 -3,-0.1 -1,-0.3 0.751 108.5 106.4 76.5 23.1 18.1 27.2 56.5 287 263DA S < - 0 0 34 -3,-1.5 -1,-0.2 3,-0.1 -3,-0.0 -0.991 51.2-164.3-143.3 135.5 18.1 31.0 56.4 288 263EA S S S+ 0 0 100 -2,-0.4 -1,-0.1 -3,-0.1 -2,-0.0 0.764 96.4 19.9 -81.8 -29.0 15.5 33.6 55.4 289 263FA S S S+ 0 0 93 2,-0.0 -1,-0.1 -6,-0.0 -2,-0.1 0.817 100.8 95.4-111.0 -40.5 17.8 36.5 55.1 290 263GA D - 0 0 81 -6,-0.1 -6,-2.9 -7,-0.1 2,-0.3 -0.058 50.8-164.5 -58.0 145.4 21.4 35.1 54.6 291 264 A T E -V 283 0D 52 -8,-0.3 2,-0.3 -96,-0.0 -8,-0.2 -0.871 13.1-147.9-134.1 162.8 23.1 34.6 51.3 292 265 A I E -V 282 0D 3 -10,-2.1 -10,-2.2 -2,-0.3 2,-0.5 -0.955 16.5-138.5-125.6 148.6 26.1 32.8 49.8 293 266 A D E -V 281 0D 61 -2,-0.3 2,-0.6 -12,-0.2 -12,-0.2 -0.931 9.7-166.3-112.6 137.9 28.1 34.0 46.8 294 267 A V E -V 280 0D 4 -14,-3.0 -14,-2.6 -2,-0.5 2,-0.4 -0.964 26.3-171.6-118.6 111.0 29.2 31.5 44.2 295 268 A S E +V 279 0D 55 -2,-0.6 -16,-0.2 -16,-0.2 -18,-0.0 -0.858 24.8 172.8-119.3 148.1 31.9 33.3 42.1 296 269 A V E -V 278 0D 1 -18,-2.7 -18,-3.0 -2,-0.4 2,-0.1 -0.988 40.9-105.9-137.4 146.1 33.9 32.9 39.0 297 270 A P E > -V 277 0D 51 0, 0.0 3,-2.0 0, 0.0 4,-0.3 -0.534 32.7-122.7 -69.9 143.6 36.3 35.5 37.3 298 271 A I G > S+ 0 0 0 -22,-3.7 3,-1.4 1,-0.3 -21,-0.1 0.766 107.8 69.3 -58.5 -28.7 34.6 36.8 34.1 299 272 A S G > S+ 0 0 33 -23,-0.4 3,-0.7 -25,-0.3 -1,-0.3 0.784 94.8 55.2 -65.0 -21.1 37.5 35.7 32.0 300 273 A K G < S+ 0 0 43 -3,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.577 99.8 64.1 -87.8 -0.6 36.5 31.9 32.6 301 274 A M G < S+ 0 0 0 -3,-1.4 14,-1.8 -4,-0.3 2,-0.4 0.255 88.8 81.7-100.6 14.7 33.0 32.8 31.3 302 275 A L E < -Y 314 0E 15 -3,-0.7 12,-0.2 12,-0.2 -37,-0.1 -0.971 58.5-169.1-120.7 129.2 34.3 33.6 27.8 303 276 A L E -Y 313 0E 32 10,-2.2 10,-3.6 -2,-0.4 2,-0.1 -0.947 28.4-113.7-118.1 136.0 35.0 31.0 25.1 304 277 A P E -Y 312 0E 86 0, 0.0 8,-0.3 0, 0.0 6,-0.0 -0.260 30.3-179.5 -64.9 133.6 36.8 31.5 21.8 305 278 A V + 0 0 72 6,-3.0 2,-0.2 -2,-0.1 7,-0.1 0.713 54.3 77.8-111.0 -17.8 34.4 31.0 19.0 306 278AA D S S- 0 0 52 5,-1.0 0, 0.0 1,-0.1 0, 0.0 -0.551 81.0-121.9 -96.1 161.6 36.7 31.6 16.1 307 278BA K S S+ 0 0 119 1,-0.3 -1,-0.1 -2,-0.2 0, 0.0 0.972 117.5 48.6 -51.2 -60.0 39.3 29.4 14.5 308 278CA S S S- 0 0 70 1,-0.1 -1,-0.3 -3,-0.0 0, 0.0 0.834 105.8-130.7 -52.2 -37.6 41.9 32.0 15.1 309 279 A G S S+ 0 0 28 2,-0.1 -2,-0.1 -6,-0.0 -1,-0.1 0.706 74.4 116.5 86.9 13.3 40.8 32.4 18.8 310 280 A E + 0 0 127 1,-0.1 -42,-2.4 -42,-0.1 -41,-0.5 0.798 66.0 59.4 -90.3 -20.3 40.6 36.3 18.6 311 281 A T E -X 267 0E 48 -44,-0.3 -6,-3.0 -43,-0.1 -5,-1.0 -0.908 68.4-164.1-115.3 126.8 36.7 36.6 19.3 312 282 A b E -XY 266 304E 9 -46,-3.4 -46,-1.9 -2,-0.5 2,-0.4 -0.861 8.0-147.6-111.7 140.9 35.2 35.2 22.6 313 283 A M E -XY 265 303E 38 -10,-3.6 -10,-2.2 -2,-0.4 -48,-0.2 -0.876 22.0-120.5-106.3 145.8 31.5 34.5 23.2 314 284 A F E - Y 0 302E 0 -50,-2.9 -50,-0.4 -2,-0.4 -12,-0.2 -0.625 16.5-131.0 -80.8 135.2 30.0 35.0 26.8 315 285 A I S S+ 0 0 0 -14,-1.8 -76,-2.1 -2,-0.2 2,-0.9 0.544 85.5 92.9 -63.3 -13.3 28.5 31.8 28.3 316 286 A V E -t 239 0D 0 -15,-0.2 -52,-0.3 -78,-0.1 -76,-0.2 -0.699 63.7-166.5 -89.9 105.1 25.2 33.7 29.2 317 287 A L E -t 240 0D 42 -78,-2.7 -76,-2.1 -2,-0.9 2,-0.3 -0.817 18.0-125.5 -99.9 122.4 23.0 33.1 26.3 318 288 A P E -t 241 0D 34 0, 0.0 2,-0.2 0, 0.0 -75,-0.1 -0.472 32.1-173.8 -73.0 127.4 19.9 35.3 26.1 319 289 A D E -t 242 0D 73 -78,-3.0 -76,-2.7 -2,-0.3 -75,-0.3 -0.601 31.6-133.9-114.9 171.9 16.6 33.4 25.8 320 290 A G S S+ 0 0 78 -2,-0.2 2,-0.0 -78,-0.2 -1,-0.0 -0.025 81.1 79.4-114.3 15.9 13.0 34.3 25.2 321 291 A G S S- 0 0 41 2,-0.2 -78,-0.1 -80,-0.1 -2,-0.1 0.029 89.1-111.0-101.9-143.1 11.6 32.1 27.9 322 297 A N S S+ 0 0 85 -80,-0.1 2,-0.4 -81,-0.0 -1,-0.0 -0.067 77.1 123.6-139.3 19.6 11.3 32.5 31.6 323 298 A Q - 0 0 40 -82,-0.1 2,-0.5 -93,-0.0 -2,-0.2 -0.653 42.7-169.4 -95.6 133.7 13.8 29.8 32.1 324 299 A F + 0 0 15 -2,-0.4 -93,-2.7 -95,-0.3 2,-0.4 -0.977 16.0 174.1-116.2 108.6 17.1 30.2 34.0 325 300 A I E -sU 231 240D 36 -85,-2.3 -85,-2.6 -2,-0.5 2,-0.7 -0.983 22.0-156.0-127.3 117.5 19.4 27.2 33.5 326 301 A V E -sU 232 239D 0 -95,-2.2 -93,-2.3 -2,-0.4 -87,-0.2 -0.891 26.9-167.0 -90.8 103.7 23.0 27.0 34.8 327 302 A G E >> -s 233 0D 0 -2,-0.7 4,-1.7 -89,-0.6 3,-1.6 -0.332 36.4 -85.1 -92.2-179.2 24.7 24.5 32.5 328 303 A N H 3> S+ 0 0 0 -92,-2.9 4,-2.3 -95,-0.6 -91,-0.2 0.688 114.9 73.8 -59.2 -23.1 28.0 22.7 32.8 329 304 A L H 34 S+ 0 0 5 -92,-2.4 -1,-0.3 1,-0.2 -91,-0.1 0.828 113.5 29.7 -63.0 -22.9 30.2 25.5 31.3 330 305 A F H X4 S+ 0 0 0 -3,-1.6 3,-1.4 -93,-0.5 -2,-0.2 0.816 116.2 55.8-103.5 -43.8 29.6 27.3 34.6 331 306 A L H >< S+ 0 0 1 -4,-1.7 3,-2.0 1,-0.3 -2,-0.2 0.768 90.1 78.8 -66.2 -20.9 29.2 24.4 37.0 332 307 A R T 3< S+ 0 0 20 -4,-2.3 -163,-0.3 1,-0.3 -1,-0.3 0.690 82.2 64.6 -60.4 -19.7 32.6 23.0 36.0 333 308 A F T < S+ 0 0 16 -3,-1.4 17,-0.9 -4,-0.1 2,-0.3 0.500 104.4 52.8 -79.3 -1.5 34.5 25.6 38.2 334 309 A F E < S- M 0 349A 12 -3,-2.0 2,-0.6 15,-0.2 -165,-0.4 -0.898 80.8-120.9-129.2 162.0 33.0 24.0 41.3 335 310 A V E - M 0 348A 2 13,-2.7 13,-1.6 -2,-0.3 2,-0.4 -0.894 42.1-154.2 -90.2 124.4 32.6 20.7 43.1 336 311 A N E -JM 167 347A 1 -169,-1.9 -169,-3.0 -2,-0.6 2,-0.5 -0.899 7.9-159.9-102.2 138.5 28.7 20.5 43.2 337 312 A V E -JM 166 346A 2 9,-2.0 9,-2.9 -2,-0.4 2,-0.7 -0.977 1.1-161.7-119.8 123.3 27.1 18.4 46.0 338 313 A Y E -JM 165 345A 0 -173,-3.8 -173,-1.5 -2,-0.5 2,-0.7 -0.917 6.6-168.1-111.7 108.3 23.5 17.2 45.5 339 314 A D E >> +JM 164 344A 8 5,-2.6 5,-1.5 -2,-0.7 4,-0.6 -0.805 14.3 173.6-102.5 104.9 22.0 16.2 48.8 340 315 A F T 45S+ 0 0 27 -177,-1.6 -176,-0.2 -2,-0.7 -1,-0.1 0.352 75.2 65.4 -93.4 7.4 18.6 14.4 48.3 341 316 A G T 45S+ 0 0 41 -178,-0.9 -1,-0.1 3,-0.1 -177,-0.1 0.922 122.8 13.9 -94.5 -44.6 18.3 13.6 52.0 342 317 A K T 45S- 0 0 149 -179,-0.2 -145,-0.2 2,-0.1 -2,-0.2 0.380 106.1-121.2-106.3 2.3 18.0 17.1 53.1 343 318 A N T <5 + 0 0 36 -4,-0.6 -146,-2.6 1,-0.2 2,-0.3 0.973 63.1 133.3 64.5 61.2 17.3 18.6 49.7 344 319 A R E < -LM 196 339A 47 -5,-1.5 -5,-2.6 -148,-0.3 2,-0.5 -0.946 50.0-135.6-138.0 155.9 20.1 21.0 49.4 345 320 A I E -LM 195 338A 0 -150,-2.6 -150,-2.4 -2,-0.3 2,-0.3 -0.981 21.5-154.3-117.6 135.3 22.6 21.9 46.7 346 321 A G E -LM 194 337A 0 -9,-2.9 -9,-2.0 -2,-0.5 2,-0.4 -0.771 7.8-169.0-102.3 136.7 26.4 22.4 47.8 347 322 A F E +LM 193 336A 6 -154,-2.7 -154,-2.7 -2,-0.3 -11,-0.2 -0.994 9.8 169.3-131.0 136.0 29.0 24.5 46.1 348 323 A A E - M 0 335A 0 -13,-1.6 -13,-2.7 -2,-0.4 -156,-0.1 -0.994 34.9-116.3-136.0 142.5 32.7 24.5 46.8 349 324 A P E - M 0 334A 64 0, 0.0 -160,-3.2 0, 0.0 -159,-0.5 -0.469 39.8-104.7 -74.9 152.5 35.5 26.1 44.8 350 325 A L B -O 188 0C 10 -17,-0.9 -162,-0.2 -162,-0.2 5,-0.1 -0.433 38.4-110.2 -73.8 141.2 38.1 23.6 43.4 351 326 A A >> - 0 0 17 -164,-3.0 3,-2.3 -2,-0.2 4,-0.6 -0.310 40.7 -86.1 -67.0 159.0 41.4 23.5 45.1 352 327 A S T 34 S+ 0 0 103 1,-0.3 -1,-0.1 2,-0.2 -164,-0.0 -0.277 121.0 41.2 -55.5 130.6 44.5 24.8 43.5 353 328 A G T 34 S+ 0 0 76 -3,-0.1 -1,-0.3 2,-0.0 -2,-0.1 0.087 115.1 53.9 117.1 -38.9 45.9 21.9 41.5 354 329 A Y T <4 S+ 0 0 88 -3,-2.3 -2,-0.2 -167,-0.1 -182,-0.1 0.280 75.1 130.2-112.7 -1.2 42.4 21.0 40.2 355 330 A E < - 0 0 90 -4,-0.6 2,-0.4 -5,-0.1 -22,-0.1 -0.364 54.7-131.2 -65.1 140.7 41.3 24.3 38.8 356 331 A N 0 0 1 -24,-0.2 -1,-0.1 1,-0.1 -2,-0.1 -0.700 360.0 360.0 -88.2 133.7 39.8 24.2 35.3 357 332 A D 0 0 148 -2,-0.4 -1,-0.1 0, 0.0 -2,-0.0 0.661 360.0 360.0 -89.3 360.0 41.3 27.0 32.9