==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=27-FEB-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 11-MAY-10 3MZ7 . COMPND 2 MOLECULE: HISTONE DEACETYLASE 8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.P.DOWLING,S.G.GATTIS,C.A.FIERKE,D.W.CHRISTIANSON . 356 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14767.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 244 68.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 39 11.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 1.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 5.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 43 12.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 113 31.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 0 1 1 1 1 1 0 0 1 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 1 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 14 A L 0 0 156 0, 0.0 110,-0.4 0, 0.0 109,-0.1 0.000 360.0 360.0 360.0-165.5 8.5 3.2 7.1 2 15 A V - 0 0 59 107,-0.2 110,-0.2 1,-0.1 39,-0.1 -0.383 360.0 -87.9 -86.7 157.8 6.3 5.8 8.7 3 16 A P - 0 0 19 0, 0.0 39,-2.4 0, 0.0 2,-0.4 -0.310 41.4-123.1 -61.3 137.8 6.0 9.6 7.9 4 17 A V E -ab 42 113A 0 108,-3.0 110,-1.9 37,-0.2 2,-0.5 -0.711 21.1-162.7 -77.3 137.2 8.5 11.8 9.7 5 18 A Y E -ab 43 114A 9 37,-3.4 39,-1.8 -2,-0.4 2,-0.3 -0.980 13.5-142.7-119.8 112.7 6.9 14.6 11.8 6 19 A I E +a 44 0A 7 108,-2.5 2,-0.3 -2,-0.5 110,-0.3 -0.592 43.7 133.9 -79.8 132.8 9.4 17.3 12.6 7 20 A Y + 0 0 48 37,-2.0 3,-0.1 -2,-0.3 -2,-0.1 -0.896 24.9 162.8-175.5 141.6 8.8 18.6 16.2 8 21 A S > - 0 0 12 -2,-0.3 4,-2.1 37,-0.1 3,-0.2 -0.924 45.6-112.8-159.9 158.2 10.0 19.6 19.6 9 22 A P H > S+ 0 0 90 0, 0.0 4,-2.1 0, 0.0 5,-0.1 0.907 118.0 46.2 -56.0 -36.7 8.6 21.7 22.4 10 23 A E H > S+ 0 0 128 2,-0.2 4,-2.1 1,-0.2 5,-0.1 0.742 107.3 55.0 -79.2 -32.7 11.1 24.4 21.9 11 24 A Y H > S+ 0 0 8 -3,-0.2 4,-2.5 2,-0.2 5,-0.2 0.921 110.6 47.8 -63.5 -47.0 10.8 24.6 18.1 12 25 A V H X S+ 0 0 14 -4,-2.1 4,-2.9 2,-0.2 14,-0.2 0.948 109.8 50.5 -59.7 -53.2 7.1 25.2 18.5 13 26 A S H X S+ 0 0 74 -4,-2.1 4,-0.7 1,-0.2 -1,-0.2 0.904 111.8 51.2 -48.4 -43.9 7.6 27.9 21.2 14 27 A M H >< S+ 0 0 31 -4,-2.1 3,-1.1 1,-0.2 -2,-0.2 0.922 111.8 43.6 -58.7 -51.1 10.0 29.5 18.9 15 28 A C H >< S+ 0 0 3 -4,-2.5 3,-1.6 1,-0.3 9,-0.2 0.789 102.7 68.7 -70.7 -29.6 7.6 29.5 15.9 16 29 A D H 3< S+ 0 0 17 -4,-2.9 7,-1.5 1,-0.2 -1,-0.3 0.794 89.5 66.3 -51.4 -30.0 4.8 30.7 18.2 17 30 A S T << + 0 0 56 -3,-1.1 2,-0.3 -4,-0.7 -1,-0.2 0.583 67.3 119.0 -66.8 -21.6 6.7 34.0 18.5 18 31 A L X - 0 0 20 -3,-1.6 3,-1.6 3,-0.2 6,-0.2 -0.412 62.2-142.7 -62.0 120.7 6.2 35.0 14.8 19 32 A A T 3 S+ 0 0 70 -2,-0.3 -1,-0.2 1,-0.3 -3,-0.0 0.725 93.6 50.8 -71.3 -22.7 4.2 38.2 15.0 20 33 A K T 3 S+ 0 0 77 1,-0.2 -1,-0.3 111,-0.1 -2,-0.1 0.756 122.5 30.0 -81.9 -23.4 1.9 37.6 12.1 21 34 A I S X S- 0 0 21 -3,-1.6 3,-2.3 -6,-0.2 4,-0.4 -0.271 82.4-169.7-130.6 54.2 0.9 34.1 13.2 22 35 A P T 3 S- 0 0 69 0, 0.0 -5,-0.2 0, 0.0 -6,-0.1 -0.115 73.1 -9.1 -57.1 131.3 1.0 34.1 17.0 23 36 A K T 3> S+ 0 0 119 -7,-1.5 4,-2.1 -10,-0.1 -7,-0.2 0.556 93.9 126.5 63.1 9.1 0.6 30.6 18.6 24 37 A R H <> + 0 0 8 -3,-2.3 4,-2.8 -9,-0.2 5,-0.2 0.907 69.3 56.0 -60.7 -43.5 -0.3 29.1 15.2 25 38 A A H > S+ 0 0 7 -4,-0.4 4,-2.2 1,-0.2 -1,-0.2 0.922 109.3 45.5 -58.2 -43.1 2.4 26.5 15.6 26 39 A S H > S+ 0 0 20 -14,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.868 111.4 53.3 -64.9 -41.4 1.0 25.3 19.0 27 40 A M H X S+ 0 0 13 -4,-2.1 4,-2.1 2,-0.2 5,-0.2 0.952 110.4 46.3 -58.7 -46.7 -2.5 25.3 17.6 28 41 A V H X S+ 0 0 6 -4,-2.8 4,-2.3 1,-0.2 -2,-0.2 0.961 118.6 40.8 -62.2 -56.1 -1.6 23.1 14.6 29 42 A H H X S+ 0 0 11 -4,-2.2 4,-2.7 1,-0.2 -1,-0.2 0.828 111.7 55.5 -57.7 -40.1 0.4 20.6 16.8 30 43 A S H X S+ 0 0 11 -4,-2.6 4,-2.2 2,-0.2 -1,-0.2 0.880 111.0 45.7 -62.8 -39.3 -2.1 20.6 19.6 31 44 A L H X S+ 0 0 0 -4,-2.1 4,-0.9 2,-0.2 -2,-0.2 0.897 111.4 50.4 -73.2 -40.4 -4.8 19.6 17.2 32 45 A I H ><>S+ 0 0 0 -4,-2.3 5,-1.6 -5,-0.2 3,-0.7 0.921 112.6 50.1 -59.6 -44.2 -2.7 17.0 15.5 33 46 A E H ><5S+ 0 0 93 -4,-2.7 3,-2.4 1,-0.2 -2,-0.2 0.918 103.1 58.2 -56.5 -47.2 -2.0 15.7 19.1 34 47 A A H 3<5S+ 0 0 34 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.723 107.0 48.8 -63.1 -22.2 -5.7 15.6 20.0 35 48 A Y T <<5S- 0 0 27 -4,-0.9 -1,-0.3 -3,-0.7 -2,-0.2 0.335 111.2-122.9 -99.5 2.7 -6.3 13.2 17.1 36 49 A A T X>5 + 0 0 36 -3,-2.4 3,-1.2 -4,-0.1 4,-0.6 0.581 69.5 133.6 73.9 16.9 -3.4 11.0 18.1 37 50 A L T 34< + 0 0 2 -5,-1.6 3,-0.4 1,-0.3 -4,-0.2 0.764 62.5 65.3 -75.9 -25.6 -1.6 11.3 14.8 38 51 A H T >4 S+ 0 0 48 -6,-0.4 3,-0.9 1,-0.2 -1,-0.3 0.743 95.0 62.5 -63.6 -23.0 1.8 11.9 16.3 39 52 A K T <4 S+ 0 0 170 -3,-1.2 -1,-0.2 1,-0.2 -2,-0.2 0.918 103.1 48.7 -66.9 -37.2 1.4 8.3 17.6 40 53 A Q T 3< S+ 0 0 78 -4,-0.6 2,-0.3 -3,-0.4 -1,-0.2 0.175 109.7 61.2 -92.5 17.7 1.4 7.1 14.0 41 54 A M S < S- 0 0 11 -3,-0.9 2,-0.6 -39,-0.1 -37,-0.2 -0.914 85.1-107.1-137.3 160.0 4.5 9.1 12.9 42 55 A R E -a 4 0A 99 -39,-2.4 -37,-3.4 -2,-0.3 2,-0.5 -0.831 32.4-142.9 -90.8 125.9 8.2 9.3 13.8 43 56 A I E -a 5 0A 76 -2,-0.6 2,-0.4 -39,-0.2 -37,-0.2 -0.735 19.3-173.0 -92.5 126.7 9.0 12.5 15.7 44 57 A V E -a 6 0A 25 -39,-1.8 -37,-2.0 -2,-0.5 57,-0.1 -0.982 24.5-125.1-128.4 127.1 12.4 14.0 14.9 45 58 A K - 0 0 150 -2,-0.4 -37,-0.1 -39,-0.2 2,-0.1 -0.521 31.6-125.9 -68.5 123.9 14.0 17.0 16.7 46 59 A P - 0 0 17 0, 0.0 2,-0.3 0, 0.0 51,-0.2 -0.459 18.9-132.2 -66.5 144.0 14.8 19.7 14.1 47 60 A K - 0 0 143 49,-0.6 2,-0.3 -2,-0.1 53,-0.2 -0.726 23.3-110.8 -87.3 146.9 18.4 20.8 14.1 48 61 A V - 0 0 99 -2,-0.3 2,-0.3 48,-0.1 45,-0.2 -0.626 38.8-111.7 -70.4 134.1 19.2 24.6 14.1 49 62 A A - 0 0 3 43,-1.5 47,-0.1 -2,-0.3 46,-0.1 -0.539 30.6-133.7 -72.6 130.6 20.6 25.7 10.7 50 63 A S > - 0 0 54 -2,-0.3 4,-1.9 1,-0.1 5,-0.2 -0.255 24.0-105.7 -77.4 167.7 24.3 26.7 10.9 51 64 A M H > S+ 0 0 57 1,-0.2 4,-1.3 2,-0.2 -1,-0.1 0.854 121.6 49.0 -61.1 -35.2 25.6 29.8 9.3 52 65 A E H 4 S+ 0 0 170 2,-0.2 -1,-0.2 1,-0.2 4,-0.1 0.888 107.5 54.1 -75.6 -35.6 27.2 27.8 6.5 53 66 A E H >4 S+ 0 0 59 1,-0.2 3,-1.3 2,-0.2 4,-0.2 0.883 108.8 48.6 -62.7 -40.6 24.1 25.8 5.8 54 67 A M H >X S+ 0 0 1 -4,-1.9 4,-2.5 1,-0.3 3,-1.4 0.813 102.6 63.2 -70.1 -29.0 22.1 29.0 5.3 55 68 A A T 3< S+ 0 0 35 -4,-1.3 -1,-0.3 1,-0.3 -2,-0.2 0.444 76.3 87.6 -76.8 1.3 24.7 30.3 3.0 56 69 A T T <4 S+ 0 0 73 -3,-1.3 -1,-0.3 -4,-0.1 -2,-0.2 0.813 119.6 0.8 -62.1 -29.0 24.0 27.3 0.7 57 70 A F T <4 S+ 0 0 36 -3,-1.4 -2,-0.2 -4,-0.2 -3,-0.1 0.670 123.8 69.5-117.2 -53.9 21.4 29.8 -0.7 58 71 A H S < S- 0 0 4 -4,-2.5 68,-0.2 1,-0.1 67,-0.1 -0.405 81.3-110.1 -77.5 148.2 21.6 33.1 1.2 59 72 A T > - 0 0 44 66,-2.2 4,-2.7 1,-0.1 5,-0.2 -0.367 18.4-123.9 -71.7 152.7 24.5 35.6 0.9 60 73 A D H > S+ 0 0 87 2,-0.2 4,-2.5 1,-0.2 5,-0.3 0.908 111.5 54.8 -62.3 -40.5 26.9 36.2 3.7 61 74 A A H > S+ 0 0 48 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.933 111.5 43.8 -60.3 -49.0 26.2 39.9 3.7 62 75 A Y H > S+ 0 0 0 1,-0.2 4,-2.9 2,-0.2 -2,-0.2 0.962 114.6 49.9 -55.6 -53.6 22.5 39.4 4.1 63 76 A L H X S+ 0 0 0 -4,-2.7 4,-1.8 1,-0.2 -2,-0.2 0.842 110.9 46.8 -61.7 -40.7 22.9 36.7 6.7 64 77 A Q H X S+ 0 0 100 -4,-2.5 4,-2.6 2,-0.2 -1,-0.2 0.920 112.7 51.5 -70.3 -41.2 25.3 38.8 8.9 65 78 A H H X S+ 0 0 48 -4,-2.2 4,-2.2 -5,-0.3 5,-0.4 0.985 107.5 52.0 -52.8 -58.6 23.0 41.7 8.6 66 79 A L H X S+ 0 0 0 -4,-2.9 4,-0.8 1,-0.3 22,-0.4 0.835 111.9 48.1 -43.2 -46.2 20.0 39.6 9.7 67 80 A Q H < S+ 0 0 74 -4,-1.8 3,-0.4 -5,-0.2 4,-0.4 0.928 109.8 50.1 -65.2 -49.3 22.0 38.5 12.7 68 81 A K H >X S+ 0 0 149 -4,-2.6 3,-1.9 1,-0.2 4,-0.8 0.948 111.8 46.4 -56.5 -53.6 23.1 42.0 13.8 69 82 A V H 3< S+ 0 0 11 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.697 102.6 67.7 -62.1 -19.5 19.6 43.5 13.6 70 83 A S T 3< S+ 0 0 10 -4,-0.8 16,-1.5 -3,-0.4 -1,-0.3 0.623 99.3 51.7 -71.7 -16.0 18.4 40.5 15.6 71 84 A Q T <4 0 0 150 -3,-1.9 -2,-0.2 -4,-0.4 -1,-0.2 0.743 360.0 360.0 -93.5 -29.1 20.4 41.7 18.5 72 85 A E < 0 0 148 -4,-0.8 -3,-0.1 12,-0.1 13,-0.0 0.157 360.0 360.0-129.9 360.0 19.0 45.3 18.6 73 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 74 95 A E 0 0 201 0, 0.0 2,-0.1 0, 0.0 4,-0.0 0.000 360.0 360.0 360.0 30.4 18.4 47.5 4.4 75 96 A Y - 0 0 74 -13,-0.1 53,-2.3 3,-0.0 -9,-0.0 -0.546 360.0 -63.9-119.5 60.1 17.9 44.0 2.9 76 97 A G S S+ 0 0 34 51,-0.2 2,-2.0 1,-0.1 5,-0.4 0.490 93.6 138.8 73.9 5.3 14.1 44.1 2.5 77 98 A L + 0 0 25 3,-0.1 6,-0.6 52,-0.1 -1,-0.1 -0.194 39.5 111.3 -77.9 49.9 13.6 44.3 6.2 78 99 A G S S- 0 0 41 -2,-2.0 51,-0.0 4,-0.2 -3,-0.0 0.318 83.1 -32.6 -98.5-138.8 10.8 46.9 5.9 79 100 A Y S S+ 0 0 225 1,-0.2 -2,-0.0 2,-0.1 0, 0.0 0.940 137.5 38.1 -50.1 -59.0 7.0 47.0 6.4 80 101 A L S S+ 0 0 71 1,-0.3 -1,-0.2 -4,-0.1 49,-0.1 0.835 130.5 30.9 -71.0 -29.1 6.3 43.4 5.5 81 102 A C S S- 0 0 1 -5,-0.4 -1,-0.3 47,-0.1 -2,-0.1 -0.619 81.8-173.2-125.0 72.4 9.5 42.0 7.2 82 103 A P - 0 0 42 0, 0.0 2,-1.7 0, 0.0 -4,-0.2 -0.357 32.2-113.3 -74.7 150.1 10.3 44.3 10.1 83 104 A A + 0 0 41 -6,-0.6 2,-0.1 4,-0.0 -11,-0.1 -0.482 51.6 164.8 -85.3 73.8 13.6 43.7 11.9 84 105 A T > - 0 0 59 -2,-1.7 3,-1.2 1,-0.1 2,-0.2 -0.301 43.2 -77.2 -86.9 172.2 12.5 42.5 15.4 85 106 A E T 3 S+ 0 0 133 1,-0.2 -14,-0.2 2,-0.1 -15,-0.1 -0.452 111.1 14.1 -75.5 134.0 14.5 40.8 18.1 86 107 A G T 3> S+ 0 0 15 -16,-1.5 4,-2.0 -2,-0.2 3,-0.4 0.427 83.9 124.7 87.3 0.3 15.3 37.1 17.8 87 108 A I H <> + 0 0 5 -3,-1.2 4,-2.5 1,-0.2 5,-0.2 0.932 69.3 57.2 -63.4 -41.3 14.4 37.0 14.1 88 109 A F H > S+ 0 0 18 -22,-0.4 4,-2.3 1,-0.2 -1,-0.2 0.875 110.2 45.8 -50.3 -40.7 17.8 35.5 13.1 89 110 A D H > S+ 0 0 92 -3,-0.4 4,-2.5 2,-0.2 -1,-0.2 0.839 110.4 49.8 -74.6 -42.4 17.2 32.6 15.5 90 111 A Y H X S+ 0 0 54 -4,-2.0 4,-2.2 2,-0.2 5,-0.2 0.891 112.2 51.6 -61.1 -37.7 13.6 31.8 14.5 91 112 A A H X S+ 0 0 0 -4,-2.5 4,-3.0 -5,-0.2 5,-0.2 0.957 110.3 46.2 -66.5 -51.6 14.9 31.9 10.9 92 113 A A H X S+ 0 0 4 -4,-2.3 4,-3.0 -5,-0.2 -43,-1.5 0.919 112.0 53.7 -49.5 -49.2 17.7 29.4 11.7 93 114 A A H X S+ 0 0 6 -4,-2.5 4,-1.8 2,-0.2 -2,-0.2 0.907 113.1 40.3 -54.3 -48.6 15.2 27.2 13.6 94 115 A I H X S+ 0 0 1 -4,-2.2 4,-1.8 2,-0.2 -2,-0.2 0.925 115.7 52.2 -74.2 -40.9 12.7 27.0 10.7 95 116 A G H X S+ 0 0 0 -4,-3.0 4,-2.3 -5,-0.2 -2,-0.2 0.907 111.7 46.2 -54.1 -44.1 15.6 26.6 8.1 96 117 A G H X S+ 0 0 2 -4,-3.0 4,-2.2 1,-0.2 -49,-0.6 0.859 108.7 56.1 -70.7 -34.0 17.1 23.8 10.2 97 118 A A H X S+ 0 0 0 -4,-1.8 4,-1.8 -5,-0.2 -1,-0.2 0.838 110.3 44.1 -63.6 -42.3 13.7 22.1 10.5 98 119 A T H X S+ 0 0 0 -4,-1.8 4,-1.9 2,-0.2 -2,-0.2 0.920 115.0 48.5 -69.1 -46.1 13.2 22.0 6.7 99 120 A I H X S+ 0 0 8 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.847 109.1 54.4 -58.2 -38.9 16.8 20.8 6.1 100 121 A T H X S+ 0 0 5 -4,-2.2 4,-2.7 -53,-0.2 -1,-0.2 0.954 106.9 49.7 -64.9 -45.7 16.4 18.2 8.8 101 122 A A H X S+ 0 0 0 -4,-1.8 4,-1.8 1,-0.2 -1,-0.2 0.871 109.4 52.8 -58.7 -40.4 13.3 16.8 7.1 102 123 A A H X S+ 0 0 0 -4,-1.9 4,-1.8 2,-0.2 -1,-0.2 0.909 107.9 51.5 -60.3 -47.4 15.3 16.8 3.8 103 124 A Q H X S+ 0 0 51 -4,-2.5 4,-2.5 2,-0.2 3,-0.3 0.945 106.3 53.6 -54.2 -48.4 18.0 14.7 5.5 104 125 A C H <>S+ 0 0 6 -4,-2.7 5,-1.1 1,-0.2 6,-0.8 0.905 109.0 49.6 -55.7 -39.8 15.4 12.2 6.8 105 126 A L H ><5S+ 0 0 4 -4,-1.8 3,-0.9 -5,-0.2 -1,-0.2 0.828 109.6 51.8 -68.3 -36.5 14.1 11.7 3.2 106 127 A I H 3<5S+ 0 0 22 -4,-1.8 2,-0.2 -3,-0.3 -2,-0.2 0.977 105.4 53.4 -59.5 -57.3 17.7 11.2 2.0 107 128 A D T 3<5S- 0 0 103 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.210 110.6-122.1 -70.5 22.0 18.5 8.5 4.5 108 129 A G T < 5S+ 0 0 56 -3,-0.9 -1,-0.2 -2,-0.2 -3,-0.2 0.578 71.5 137.6 49.1 9.8 15.4 6.6 3.4 109 130 A M S + c 0 280A 2 164,-2.6 3,-1.9 -2,-0.5 166,-1.3 -0.727 8.5 178.5-126.3 85.3 7.6 20.7 8.7 116 137 A W T 3 S+ 0 0 11 -110,-0.3 166,-0.4 1,-0.3 -1,-0.1 0.804 79.9 57.7 -53.2 -28.3 4.3 22.5 9.1 117 138 A S T 3 S+ 0 0 18 164,-0.2 -1,-0.3 163,-0.1 3,-0.1 0.438 97.1 77.9 -88.9 3.1 6.1 25.7 10.3 118 139 A G < + 0 0 1 -3,-1.9 3,-0.1 161,-0.2 163,-0.1 -0.076 40.3 100.9 -88.0-167.8 8.2 25.9 7.1 119 140 A G + 0 0 1 1,-0.1 2,-2.1 161,-0.1 164,-0.2 0.666 33.1 158.4 104.1 20.3 7.1 27.1 3.6 120 141 A W > + 0 0 21 1,-0.2 3,-0.8 14,-0.1 -1,-0.1 -0.418 11.7 166.0 -76.5 76.6 8.6 30.7 3.6 121 142 A H T 3 + 0 0 6 -2,-2.1 43,-1.1 1,-0.2 42,-0.9 0.422 54.3 63.6 -85.6 -4.7 8.6 30.9 -0.1 122 143 A H T 3 + 0 0 8 7,-0.3 -1,-0.2 41,-0.2 8,-0.1 0.694 69.9 111.9 -91.9 -26.2 9.3 34.7 -0.8 123 144 A A < - 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