==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 01-NOV-02 1N4V . COMPND 2 MOLECULE: CHOLESTEROL OXIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES SP.; . AUTHOR A.VRIELINK,P.I.LARIO . 498 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18356.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 330 66.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 26 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 77 15.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 40 8.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 45 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 102 20.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 2 1 1 0 0 2 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 2 1 2 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A G 0 0 86 0, 0.0 272,-2.1 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0-169.6 26.2 0.8 48.8 2 10 A Y E +a 273 0A 136 270,-0.2 272,-0.2 252,-0.1 3,-0.1 -0.985 360.0 174.5-124.4 134.0 29.1 -0.8 47.1 3 11 A V E -a 274 0A 30 270,-2.4 272,-0.5 -2,-0.4 273,-0.2 -0.992 35.5-126.3-137.3 139.7 29.3 -3.4 44.3 4 12 A P E S+ 0 0 41 0, 0.0 272,-2.4 0, 0.0 271,-2.0 0.911 94.0 19.4 -52.2 -52.9 32.5 -4.6 42.7 5 13 A A E -ab 276 28A 0 22,-2.1 24,-2.3 270,-0.2 2,-0.4 -0.982 65.0-167.1-121.3 141.3 31.4 -3.8 39.2 6 14 A V E -ab 277 29A 0 270,-2.2 272,-2.8 -2,-0.4 2,-0.5 -0.982 3.3-164.3-118.7 136.1 28.8 -1.6 37.9 7 15 A V E -ab 278 30A 0 22,-2.5 24,-2.4 -2,-0.4 2,-0.6 -0.986 13.1-145.3-115.2 124.5 27.5 -1.6 34.3 8 16 A I E +ab 279 31A 8 270,-2.8 272,-2.2 -2,-0.5 24,-0.2 -0.820 67.4 3.9 -90.7 121.0 25.5 1.4 33.1 9 17 A G - 0 0 8 22,-3.2 22,-0.2 -2,-0.6 272,-0.2 -0.110 66.6-119.6 92.4 170.4 22.8 0.4 30.7 10 18 A T + 0 0 0 93,-0.3 95,-0.4 270,-0.2 -1,-0.1 -0.029 67.5 111.8-144.2 29.6 21.7 -3.0 29.3 11 19 A G S > S- 0 0 12 269,-0.8 4,-2.7 94,-0.1 5,-0.2 0.096 87.7 -61.8 -82.7-157.1 22.3 -2.8 25.6 12 20 A Y H > S+ 0 0 22 2,-0.2 4,-2.2 1,-0.2 5,-0.3 0.938 133.0 42.1 -62.6 -51.7 24.8 -4.7 23.5 13 21 A G H > S+ 0 0 1 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.924 118.7 46.6 -61.1 -43.0 28.0 -3.4 25.1 14 22 A A H > S+ 0 0 0 266,-0.4 4,-2.7 2,-0.2 -1,-0.2 0.895 111.5 50.4 -63.3 -45.3 26.6 -3.6 28.5 15 23 A A H X S+ 0 0 0 -4,-2.7 4,-2.1 2,-0.2 5,-0.2 0.900 111.6 46.8 -65.9 -43.6 25.2 -7.1 28.1 16 24 A V H X S+ 0 0 0 -4,-2.2 4,-2.1 -5,-0.2 5,-0.2 0.946 113.7 49.9 -60.3 -46.7 28.3 -8.7 26.8 17 25 A S H X S+ 0 0 2 -4,-1.9 4,-2.5 -5,-0.3 -2,-0.2 0.932 111.0 47.8 -60.3 -49.1 30.4 -7.0 29.5 18 26 A A H X S+ 0 0 0 -4,-2.7 4,-2.5 1,-0.2 -1,-0.2 0.883 109.3 53.3 -63.5 -38.4 28.1 -8.2 32.3 19 27 A L H X S+ 0 0 1 -4,-2.1 4,-2.5 2,-0.2 -1,-0.2 0.955 113.0 42.6 -59.5 -48.4 28.0 -11.8 31.1 20 28 A R H X S+ 0 0 43 -4,-2.1 4,-1.5 1,-0.2 -2,-0.2 0.893 113.4 52.5 -72.2 -35.9 31.8 -12.1 31.0 21 29 A L H <>S+ 0 0 0 -4,-2.5 5,-2.5 -5,-0.2 3,-0.3 0.932 111.2 47.4 -59.0 -47.7 32.2 -10.3 34.3 22 30 A G H ><5S+ 0 0 5 -4,-2.5 3,-1.5 1,-0.2 -2,-0.2 0.906 109.3 52.2 -64.0 -40.6 29.7 -12.7 35.9 23 31 A E H 3<5S+ 0 0 114 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.766 106.8 55.0 -62.9 -28.0 31.4 -15.7 34.4 24 32 A A T 3<5S- 0 0 53 -4,-1.5 -1,-0.3 -3,-0.3 -2,-0.2 0.423 122.8-108.3 -81.8 -1.7 34.7 -14.4 35.9 25 33 A G T < 5S+ 0 0 43 -3,-1.5 2,-0.7 -4,-0.3 -3,-0.2 0.647 71.1 143.4 84.4 15.1 33.1 -14.3 39.3 26 34 A V < - 0 0 16 -5,-2.5 2,-0.3 -6,-0.2 -1,-0.2 -0.798 53.0-127.1 -92.9 116.1 32.8 -10.5 39.6 27 35 A Q - 0 0 70 -2,-0.7 -22,-2.1 -3,-0.1 2,-0.4 -0.474 37.4-171.2 -63.6 123.7 29.6 -9.4 41.3 28 36 A T E -bc 5 234A 0 205,-2.9 207,-2.1 -2,-0.3 2,-0.5 -0.974 21.1-160.3-132.2 131.9 28.1 -7.0 38.9 29 37 A L E -bc 6 235A 5 -24,-2.3 -22,-2.5 -2,-0.4 2,-0.4 -0.972 10.7-156.6-110.8 123.4 25.1 -4.5 39.1 30 38 A M E -bc 7 236A 0 205,-3.0 207,-2.7 -2,-0.5 2,-0.5 -0.867 4.6-155.7 -99.3 133.3 23.5 -3.2 35.9 31 39 A L E -bc 8 237A 2 -24,-2.4 -22,-3.2 -2,-0.4 2,-0.5 -0.960 13.4-177.9-111.1 116.1 21.6 0.1 36.1 32 40 A E E - c 0 238A 12 205,-2.7 208,-2.4 -2,-0.5 207,-0.6 -0.963 21.6-156.4-119.1 127.5 19.0 0.6 33.5 33 41 A M S S+ 0 0 32 -2,-0.5 208,-0.2 206,-0.3 227,-0.1 0.776 77.7 60.5 -74.3 -25.8 16.9 3.8 33.2 34 42 A G S S- 0 0 0 1,-0.2 205,-2.2 206,-0.1 206,-0.3 -0.139 92.9 -79.8 -89.6-172.7 14.1 2.0 31.3 35 43 A Q - 0 0 29 67,-0.5 69,-2.6 50,-0.4 2,-0.7 -0.482 29.0-113.6 -87.0 159.1 11.8 -0.9 32.3 36 44 A L - 0 0 78 67,-0.2 2,-1.5 -2,-0.2 3,-0.3 -0.842 39.4-138.5 -80.7 114.4 12.1 -4.6 32.3 37 45 A W + 0 0 16 -2,-0.7 9,-0.1 67,-0.3 10,-0.1 -0.627 68.3 105.5 -88.1 86.7 9.5 -5.4 29.6 38 46 A N + 0 0 79 -2,-1.5 -1,-0.2 8,-0.1 8,-0.1 0.286 45.0 102.4-146.2 14.3 7.7 -8.4 30.9 39 47 A Q S S- 0 0 136 -3,-0.3 6,-0.1 7,-0.1 5,-0.0 -0.889 70.1-123.3-108.7 119.6 4.2 -7.1 32.1 40 48 A P - 0 0 87 0, 0.0 6,-0.2 0, 0.0 5,-0.1 -0.366 33.4-147.5 -56.4 135.1 1.2 -7.8 29.9 41 49 A G > - 0 0 25 4,-2.5 3,-2.1 6,-0.1 5,-0.1 -0.035 38.7 -67.0 -91.9-166.3 -0.5 -4.4 29.2 42 50 A P T 3 S+ 0 0 128 0, 0.0 4,-0.1 0, 0.0 -1,-0.0 0.747 135.1 48.4 -61.0 -24.4 -4.1 -3.4 28.6 43 51 A D T 3 S- 0 0 64 2,-0.3 3,-0.1 3,-0.0 4,-0.1 0.255 121.2-106.7 -93.7 9.3 -4.3 -5.4 25.4 44 52 A G S < S+ 0 0 49 -3,-2.1 2,-0.3 1,-0.3 0, 0.0 0.377 89.9 105.3 81.0 -4.2 -2.8 -8.5 27.0 45 53 A N S S- 0 0 58 1,-0.1 -4,-2.5 -5,-0.1 -2,-0.3 -0.775 70.7-135.3-107.4 154.1 0.5 -7.9 25.2 46 54 A I S S+ 0 0 46 -2,-0.3 2,-0.3 -6,-0.2 -7,-0.1 0.943 91.3 32.7 -65.1 -48.9 3.8 -6.6 26.5 47 55 A F S S- 0 0 14 -10,-0.1 2,-0.2 -6,-0.1 165,-0.1 -0.787 79.9-125.2-111.4 148.0 4.4 -4.3 23.5 48 56 A C - 0 0 1 163,-0.4 163,-0.2 -2,-0.3 2,-0.2 -0.518 27.7-121.2 -83.7 167.2 2.1 -2.4 21.3 49 57 A G > - 0 0 3 3,-0.2 3,-0.6 -2,-0.2 159,-0.2 -0.435 26.0-103.6 -93.4 173.3 2.1 -2.8 17.6 50 58 A M T 3 S+ 0 0 10 157,-3.1 158,-0.1 1,-0.2 27,-0.1 0.753 121.1 51.1 -75.0 -19.9 2.7 -0.1 14.9 51 59 A L T 3 S+ 0 0 71 156,-0.4 -1,-0.2 155,-0.2 157,-0.1 0.500 118.6 36.8 -88.9 -11.7 -1.1 -0.0 14.1 52 60 A N S < S+ 0 0 83 -3,-0.6 -3,-0.2 2,-0.0 -1,-0.2 -0.295 78.9 175.0-135.9 53.2 -2.1 0.4 17.7 53 61 A P + 0 0 11 0, 0.0 2,-0.2 0, 0.0 11,-0.1 -0.334 6.2 161.5 -64.5 144.6 0.5 2.7 19.3 54 62 A D > - 0 0 43 -5,-0.1 3,-2.4 9,-0.1 4,-0.3 -0.664 61.0 -60.0-141.4-163.8 -0.1 3.8 22.9 55 63 A K G > S+ 0 0 81 1,-0.3 3,-1.5 -2,-0.2 31,-0.2 0.780 126.3 68.9 -61.7 -23.8 2.0 5.2 25.8 56 64 A R G 3 S+ 0 0 11 1,-0.3 31,-2.5 30,-0.2 -1,-0.3 0.647 90.9 64.4 -64.3 -17.1 4.2 2.0 25.7 57 65 A S G < S+ 0 0 4 -3,-2.4 31,-0.4 29,-0.2 2,-0.4 0.629 101.5 51.6 -75.8 -19.8 5.5 3.2 22.3 58 66 A S S < S- 0 0 10 -3,-1.5 28,-1.4 -4,-0.3 2,-1.0 -0.979 70.7-130.5-139.8 134.3 7.2 6.3 23.5 59 67 A W B S-H 85 0B 37 29,-2.1 26,-0.2 -2,-0.4 31,-0.2 -0.725 90.7 -34.9 -82.0 102.1 9.7 7.5 26.1 60 68 A F S S+ 0 0 64 24,-3.1 2,-0.3 -2,-1.0 -1,-0.2 0.883 97.1 137.7 48.8 58.2 8.1 10.5 27.7 61 69 A K - 0 0 39 -3,-0.3 23,-0.2 21,-0.3 -1,-0.2 -0.889 51.9-140.7-119.8 159.7 6.2 12.0 24.8 62 70 A N S S+ 0 0 119 -2,-0.3 19,-1.8 1,-0.2 2,-0.3 0.410 85.5 33.7-103.5 4.3 2.6 13.4 24.8 63 71 A R B S-I 80 0C 99 17,-0.3 17,-0.2 -9,-0.1 -1,-0.2 -0.974 81.6-116.3-154.0 140.6 1.6 12.0 21.4 64 72 A T - 0 0 3 15,-2.4 2,-0.3 -2,-0.3 -9,-0.1 -0.340 30.2-144.9 -68.0 160.7 2.5 8.8 19.4 65 73 A E - 0 0 69 13,-0.1 3,-0.1 -8,-0.1 -1,-0.0 -0.942 14.1-111.6-129.1 149.9 4.3 9.2 16.1 66 74 A A - 0 0 21 -2,-0.3 5,-0.2 1,-0.1 3,-0.1 -0.554 44.3 -95.4 -73.0 145.4 4.2 7.2 12.9 67 75 A P > - 0 0 19 0, 0.0 3,-2.7 0, 0.0 4,-0.3 -0.314 57.8 -86.3 -55.7 140.8 7.2 5.1 11.9 68 76 A L T 3 S+ 0 0 41 1,-0.3 357,-0.1 2,-0.2 356,-0.0 -0.312 118.3 24.1 -57.9 129.4 9.4 7.1 9.6 69 77 A G T 3 S+ 0 0 1 355,-0.5 -1,-0.3 -3,-0.1 3,-0.2 0.074 112.8 72.8 103.0 -21.5 8.2 6.7 6.0 70 78 A S X> + 0 0 1 -3,-2.7 4,-2.7 1,-0.1 3,-1.8 0.318 51.8 111.0-115.1 7.0 4.7 5.8 7.0 71 79 A F H 3> S+ 0 0 106 353,-0.5 4,-1.8 -4,-0.3 5,-0.2 0.843 75.2 61.9 -48.6 -40.1 3.1 9.1 8.2 72 80 A L H 34 S+ 0 0 79 352,-0.2 -1,-0.3 1,-0.2 -2,-0.1 0.771 120.4 23.6 -61.6 -26.1 0.8 9.2 5.2 73 81 A W H <4 S+ 0 0 58 -3,-1.8 -2,-0.2 2,-0.1 -1,-0.2 0.682 127.9 42.9-109.1 -29.7 -0.9 5.9 6.2 74 82 A L H >< S+ 0 0 4 -4,-2.7 3,-1.4 1,-0.2 4,-0.4 0.513 85.7 84.6-106.3 -5.6 -0.3 5.7 10.0 75 83 A D G >< S+ 0 0 57 -4,-1.8 3,-1.8 -5,-0.4 -1,-0.2 0.875 82.7 69.4 -62.6 -26.6 -0.9 9.2 11.3 76 84 A V G 3 S+ 0 0 110 1,-0.3 -1,-0.3 -5,-0.2 -2,-0.1 0.754 99.2 47.6 -62.4 -24.2 -4.6 8.1 11.4 77 85 A V G < S+ 0 0 36 -3,-1.4 -1,-0.3 -27,-0.1 -2,-0.2 0.446 86.7 115.2 -94.6 -2.9 -3.8 5.8 14.3 78 86 A N < + 0 0 5 -3,-1.8 2,-0.3 -4,-0.4 -13,-0.1 -0.399 41.9 178.0 -71.0 147.6 -1.8 8.4 16.3 79 87 A R - 0 0 143 -2,-0.1 -15,-2.4 -25,-0.0 2,-0.1 -0.979 35.4 -95.8-144.7 153.8 -3.2 9.5 19.7 80 88 A N B -I 63 0C 124 -2,-0.3 2,-0.3 -17,-0.2 -17,-0.3 -0.481 48.7-175.7 -65.1 143.9 -2.4 11.7 22.6 81 89 A I - 0 0 24 -19,-1.8 3,-0.0 -2,-0.1 -27,-0.0 -0.955 30.1-102.2-139.6 157.6 -0.7 9.8 25.4 82 90 A D - 0 0 117 -2,-0.3 -21,-0.3 1,-0.1 2,-0.2 -0.592 50.5 -98.9 -73.5 137.5 0.5 10.3 28.9 83 91 A P + 0 0 61 0, 0.0 2,-0.3 0, 0.0 -21,-0.1 -0.435 63.2 162.0 -56.9 130.1 4.2 10.7 29.2 84 92 A Y - 0 0 31 -26,-0.4 -24,-3.1 -29,-0.2 2,-2.4 -0.958 54.9 -91.7-150.5 160.5 5.4 7.3 30.2 85 93 A A B +H 59 0B 0 177,-1.9 -50,-0.4 -2,-0.3 -26,-0.2 -0.335 65.8 165.3 -78.1 59.3 8.6 5.1 30.4 86 94 A G - 0 0 0 -2,-2.4 -29,-0.2 -28,-1.4 -30,-0.2 -0.055 45.1-105.9 -76.1-176.6 7.9 3.6 27.0 87 95 A V S S+ 0 0 0 -31,-2.5 15,-2.3 124,-0.1 2,-0.5 0.717 92.8 56.3 -92.2 -25.5 10.3 1.7 24.8 88 96 A L E -J 101 0D 20 -31,-0.4 -29,-2.1 13,-0.2 2,-0.6 -0.945 60.8-165.1-116.0 125.6 11.3 4.0 21.9 89 97 A D E -J 100 0D 13 11,-3.1 11,-2.3 -2,-0.5 2,-0.8 -0.928 8.8-160.2-113.6 113.8 12.9 7.3 22.5 90 98 A R E -J 99 0D 80 -2,-0.6 2,-0.7 9,-0.2 9,-0.2 -0.852 17.4-157.9 -85.3 110.0 13.2 9.9 19.7 91 99 A V E -J 98 0D 26 7,-3.2 7,-2.6 -2,-0.8 2,-0.7 -0.856 7.1-149.8 -96.6 110.9 16.0 12.2 21.1 92 100 A N E +J 97 0D 92 -2,-0.7 5,-0.2 5,-0.2 2,-0.2 -0.783 19.8 174.5 -93.9 118.5 15.7 15.5 19.4 93 101 A Y - 0 0 38 3,-2.9 3,-0.4 -2,-0.7 299,-0.1 -0.515 53.2 -83.6-102.6 178.3 18.9 17.6 18.8 94 102 A D S S+ 0 0 122 297,-0.4 298,-0.1 1,-0.2 300,-0.1 0.896 120.7 1.8 -58.2 -42.2 19.0 20.8 16.9 95 103 A Q S S+ 0 0 61 298,-0.4 2,-0.3 296,-0.3 -1,-0.2 0.042 126.5 59.0-136.1 30.2 19.3 19.3 13.4 96 104 A M - 0 0 3 -3,-0.4 -3,-2.9 295,-0.1 2,-0.5 -0.957 57.3-155.0-159.3 136.4 19.2 15.5 14.1 97 105 A S E -Jk 92 436D 13 338,-2.0 340,-1.7 -2,-0.3 2,-0.5 -0.978 16.0-162.8-115.3 117.9 16.7 13.1 15.7 98 106 A V E -Jk 91 437D 0 -7,-2.6 -7,-3.2 -2,-0.5 2,-0.4 -0.905 6.6-148.7-106.6 126.9 18.3 10.0 17.1 99 107 A Y E +J 90 0D 31 338,-2.8 2,-0.3 -2,-0.5 -9,-0.2 -0.816 24.4 167.9 -98.4 129.5 16.1 7.0 17.9 100 108 A V E -J 89 0D 28 -11,-2.3 -11,-3.1 -2,-0.4 2,-0.2 -0.971 33.2-112.0-139.8 152.4 17.2 4.7 20.8 101 109 A G E -J 88 0D 11 -2,-0.3 2,-0.4 -13,-0.2 6,-0.3 -0.550 21.9-158.5 -81.4 150.0 15.7 1.9 22.9 102 110 A R + 0 0 38 -15,-2.3 -67,-0.5 4,-0.3 2,-0.3 -0.936 51.8 53.6-130.2 108.7 14.8 2.3 26.6 103 111 A G S > S- 0 0 0 -2,-0.4 3,-2.7 -69,-0.3 2,-0.7 -0.903 98.7 -36.9 154.9 177.3 14.6 -0.8 28.6 104 112 A V T 3 S+ 0 0 3 -69,-2.6 117,-0.3 1,-0.3 -67,-0.3 -0.571 133.2 27.3 -71.3 110.0 16.3 -4.0 29.7 105 113 A G T > S- 0 0 0 -2,-0.7 3,-1.8 -95,-0.4 115,-0.3 0.253 96.6-146.0 113.7 -10.6 18.0 -4.9 26.4 106 114 A G G X S- 0 0 8 -3,-2.7 3,-2.0 1,-0.3 4,-0.4 -0.135 73.7 -2.5 55.7-137.9 18.3 -1.3 25.0 107 115 A G G >> S+ 0 0 27 -6,-0.3 4,-1.8 1,-0.3 3,-0.8 0.705 119.7 78.4 -63.3 -18.9 18.0 -1.1 21.3 108 116 A S G <4 S+ 0 0 1 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.755 89.1 59.2 -61.4 -20.2 17.7 -4.8 20.9 109 117 A L G <4 S+ 0 0 2 -3,-2.0 104,-0.3 -4,-0.2 -1,-0.2 0.871 118.7 25.1 -71.5 -35.5 14.1 -4.3 22.0 110 118 A V T <4 S+ 0 0 15 -3,-0.8 -2,-0.2 -4,-0.4 -1,-0.2 0.445 98.0 103.6-110.7 -9.7 13.2 -2.0 19.2 111 119 A N S < S- 0 0 37 -4,-1.8 101,-0.1 1,-0.1 100,-0.0 -0.174 78.6-110.3 -84.1 172.3 15.6 -2.8 16.3 112 120 A G - 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0 0 56 4,-2.1 3,-1.6 -2,-0.3 -4,-1.2 -0.092 62.3 -79.2 -74.0-172.6 42.8 3.0 24.6 452 460 A D T 3 S+ 0 0 28 1,-0.3 -6,-0.1 -6,-0.2 -1,-0.1 0.472 132.9 48.0 -78.5 5.4 42.3 0.3 22.0 453 461 A Y T 3 S- 0 0 50 2,-0.1 -1,-0.3 36,-0.1 40,-0.1 0.175 124.3 -95.0-124.3 10.6 40.1 -1.8 24.5 454 462 A G S < S+ 0 0 0 -3,-1.6 10,-2.4 1,-0.3 2,-0.5 0.539 70.4 152.2 83.4 13.7 37.8 1.0 25.7 455 463 A R B -G 463 0A 45 8,-0.2 -4,-2.1 1,-0.1 -1,-0.3 -0.620 52.8-116.3 -72.5 121.6 39.8 2.0 28.8 456 464 A V B > -X 450 0K 2 6,-2.7 3,-1.8 -2,-0.5 -6,-0.3 -0.384 29.9-111.2 -66.9 129.1 38.9 5.7 29.3 457 465 A A T 3 S+ 0 0 36 -8,-2.3 -154,-0.4 1,-0.2 -1,-0.1 -0.344 100.2 24.7 -63.1 137.1 42.0 7.9 28.9 458 466 A G T 3 S+ 0 0 41 1,-0.2 2,-0.3 -156,-0.1 -1,-0.2 0.259 112.7 75.7 96.5 -7.5 43.1 9.5 32.2 459 467 A Y < - 0 0 34 -3,-1.8 2,-0.3 3,-0.2 3,-0.3 -0.959 65.8-136.4-139.5 151.0 41.5 6.9 34.5 460 468 A K S S+ 0 0 146 -2,-0.3 -208,-0.1 1,-0.2 3,-0.1 -0.837 88.5 11.8-102.2 142.7 42.0 3.3 35.7 461 469 A N S S+ 0 0 15 -2,-0.3 -184,-2.4 1,-0.2 2,-0.4 0.713 95.3 119.7 63.0 28.5 39.2 0.8 36.0 462 470 A L E +f 277 0A 0 -3,-0.3 -6,-2.7 -6,-0.2 2,-0.4 -0.990 40.7 178.8-126.9 119.5 36.9 3.0 33.9 463 471 A Y E -fG 278 455A 0 -186,-2.8 -184,-3.0 -2,-0.4 2,-0.4 -0.922 26.2-153.3-132.4 146.0 35.6 1.5 30.7 464 472 A V E +f 279 0A 2 -10,-2.4 -184,-0.2 -2,-0.4 -2,-0.0 -0.945 18.1 172.5-117.3 138.6 33.3 2.3 27.7 465 473 A T + 0 0 8 -186,-2.5 -185,-0.1 -2,-0.4 25,-0.1 0.433 43.8 62.5-125.5 -1.8 31.8 -0.7 26.0 466 474 A D S > S- 0 0 7 -187,-0.3 3,-2.3 -184,-0.1 4,-0.3 -0.135 98.7 -51.2-127.3-160.9 29.2 0.4 23.4 467 475 A G G > S+ 0 0 6 1,-0.3 -25,-2.4 2,-0.2 3,-1.1 0.668 115.2 76.2 -60.0 -17.5 28.4 2.3 20.2 468 476 A S G 3 S+ 0 0 0 1,-0.2 -24,-2.6 -27,-0.2 -1,-0.3 0.733 89.3 61.1 -61.2 -21.7 30.2 5.4 21.5 469 477 A L G < S+ 0 0 2 -3,-2.3 -23,-2.7 -24,-0.2 -1,-0.2 0.685 83.8 93.0 -75.4 -26.0 33.5 3.5 20.7 470 478 A I S < S- 0 0 1 -3,-1.1 2,-2.5 -4,-0.3 -26,-0.2 -0.601 83.1-119.9 -83.1 137.1 32.8 3.2 16.9 471 479 A P - 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