==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=19-JUL-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 25-MAY-10 3N5G . COMPND 2 MOLECULE: THYMIDYLATE SYNTHASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.POZZI,D.CARDINALE,G.GUAITOLI,D.TONDI,R.LUCIANI,H.MYLLYKALL . 263 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13276.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 177 67.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 13 4.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 39 14.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 29 11.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 23 8.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 62 23.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 1 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 3 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 38 A P 0 0 175 0, 0.0 3,-0.1 0, 0.0 2,-0.0 0.000 360.0 360.0 360.0 150.5 71.7 1.2 14.0 2 39 A P - 0 0 119 0, 0.0 2,-0.2 0, 0.0 0, 0.0 -0.352 360.0 -93.5 -69.6 151.7 71.0 -2.1 15.8 3 40 A H > - 0 0 46 1,-0.1 3,-1.9 224,-0.1 4,-0.3 -0.431 28.6-134.0 -64.4 126.3 68.7 -4.8 14.3 4 41 A G T >> S+ 0 0 15 1,-0.3 3,-1.3 -2,-0.2 4,-0.6 0.756 100.9 66.4 -50.2 -30.5 65.1 -4.4 15.6 5 42 A E H 3> S+ 0 0 0 1,-0.3 4,-2.5 2,-0.2 -1,-0.3 0.754 81.5 78.1 -70.0 -20.3 64.7 -8.1 16.2 6 43 A L H <> S+ 0 0 76 -3,-1.9 4,-2.7 1,-0.2 -1,-0.3 0.812 88.3 58.5 -57.1 -25.3 67.4 -7.9 19.0 7 44 A Q H <> S+ 0 0 69 -3,-1.3 4,-2.5 -4,-0.3 -1,-0.2 0.979 106.4 45.8 -69.5 -46.4 64.7 -6.5 21.3 8 45 A Y H X S+ 0 0 0 -4,-0.6 4,-2.6 1,-0.2 5,-0.2 0.950 116.4 46.1 -57.0 -50.9 62.5 -9.5 20.9 9 46 A L H X S+ 0 0 12 -4,-2.5 4,-2.3 1,-0.2 -1,-0.2 0.901 111.2 52.0 -64.2 -35.6 65.5 -11.8 21.4 10 47 A G H X S+ 0 0 31 -4,-2.7 4,-3.0 -5,-0.3 -1,-0.2 0.881 109.7 51.1 -65.7 -33.1 66.6 -9.7 24.4 11 48 A Q H X S+ 0 0 16 -4,-2.5 4,-2.8 2,-0.2 5,-0.2 0.936 109.8 48.0 -70.5 -45.4 63.2 -10.0 25.9 12 49 A I H X S+ 0 0 1 -4,-2.6 4,-2.9 2,-0.2 5,-0.3 0.961 114.2 47.2 -53.8 -50.9 63.1 -13.8 25.5 13 50 A Q H X S+ 0 0 111 -4,-2.3 4,-2.5 -5,-0.2 -2,-0.2 0.945 110.7 51.5 -63.9 -43.2 66.5 -14.0 27.0 14 51 A H H X S+ 0 0 79 -4,-3.0 4,-3.2 1,-0.2 5,-0.4 0.893 111.6 48.5 -57.0 -41.4 65.5 -11.7 29.9 15 52 A I H X S+ 0 0 0 -4,-2.8 4,-2.2 2,-0.2 -2,-0.2 0.924 111.7 47.9 -66.7 -44.1 62.5 -13.9 30.6 16 53 A L H < S+ 0 0 30 -4,-2.9 -2,-0.2 -5,-0.2 -1,-0.2 0.939 120.7 39.5 -56.7 -42.1 64.5 -17.1 30.6 17 54 A R H < S+ 0 0 196 -4,-2.5 -2,-0.2 -5,-0.3 -1,-0.2 0.905 136.1 12.7 -77.9 -40.1 67.0 -15.5 32.9 18 55 A X H < S+ 0 0 114 -4,-3.2 -3,-0.2 -5,-0.2 -2,-0.2 0.433 91.3 120.0-123.4 -7.5 64.7 -13.5 35.3 19 56 A G < - 0 0 16 -4,-2.2 2,-0.3 -5,-0.4 14,-0.2 -0.304 52.9-137.2 -62.8 151.9 61.2 -14.8 34.7 20 57 A V E -A 32 0A 102 12,-2.4 12,-2.6 1,-0.0 2,-0.2 -0.813 25.2 -98.7-113.8 145.4 59.3 -16.4 37.5 21 58 A R E +A 31 0A 149 -2,-0.3 2,-0.3 10,-0.2 10,-0.2 -0.463 52.1 161.5 -63.6 132.5 57.2 -19.6 37.4 22 59 A K E -A 30 0A 110 8,-2.2 8,-1.7 -2,-0.2 2,-0.2 -0.971 32.1-126.9-154.8 138.1 53.5 -18.8 37.0 23 60 A D E -A 29 0A 97 -2,-0.3 6,-0.2 6,-0.2 2,-0.1 -0.535 16.2-140.1 -84.2 147.9 50.5 -20.8 35.9 24 61 A D > - 0 0 42 4,-2.3 3,-2.4 -2,-0.2 -1,-0.1 -0.371 46.4 -80.2 -94.6-177.0 48.0 -19.7 33.2 25 62 A R T 3 S+ 0 0 177 1,-0.3 -2,-0.0 2,-0.2 -1,-0.0 0.582 131.9 54.1 -70.6 -10.6 44.3 -20.3 33.6 26 63 A T T 3 S- 0 0 87 2,-0.2 -1,-0.3 3,-0.0 3,-0.1 0.251 119.5-109.2 -95.6 12.2 44.5 -24.0 32.5 27 64 A G S < S+ 0 0 49 -3,-2.4 2,-0.4 1,-0.3 -2,-0.2 0.674 73.0 144.4 67.0 17.7 47.2 -24.6 35.2 28 65 A T - 0 0 61 1,-0.1 -4,-2.3 -4,-0.0 -1,-0.3 -0.774 50.5-116.7 -88.6 135.0 49.9 -24.9 32.5 29 66 A G E +A 23 0A 9 -2,-0.4 184,-1.8 -6,-0.2 2,-0.3 -0.334 36.1 172.3 -81.9 149.5 53.2 -23.4 33.6 30 67 A T E -AB 22 212A 3 -8,-1.7 -8,-2.2 182,-0.2 2,-0.5 -0.927 36.3-117.8-139.3 165.9 55.1 -20.4 32.2 31 68 A L E -AB 21 211A 30 180,-2.4 180,-2.5 -2,-0.3 2,-0.4 -0.952 46.2-163.7-100.3 130.1 58.1 -18.2 33.0 32 69 A S E +AB 20 210A 15 -12,-2.6 -12,-2.4 -2,-0.5 2,-0.4 -0.954 27.3 178.6-128.7 137.5 56.7 -14.7 33.5 33 70 A V E - B 0 209A 22 176,-2.4 176,-2.7 -2,-0.4 2,-0.6 -0.996 25.9-136.5-129.3 134.1 57.9 -11.1 33.6 34 71 A F E S+ B 0 208A 161 -2,-0.4 174,-0.2 174,-0.2 173,-0.1 -0.856 71.3 16.0 -97.7 121.7 55.4 -8.2 34.1 35 72 A G E + 0 0 48 172,-3.0 2,-0.3 -2,-0.6 172,-0.2 0.831 67.7 161.6 91.7 101.4 55.7 -5.0 32.0 36 73 A M E - B 0 206A 24 170,-1.6 170,-2.3 -3,-0.1 2,-0.3 -0.966 13.4-170.6-142.0 163.4 57.9 -5.0 28.8 37 74 A Q E + B 0 205A 111 -2,-0.3 2,-0.3 168,-0.2 168,-0.2 -0.965 6.5 178.6-157.0 145.6 58.2 -2.9 25.7 38 75 A A E - B 0 204A 3 166,-2.0 166,-3.2 -2,-0.3 2,-0.4 -0.973 14.9-149.6-142.5 147.0 59.9 -2.9 22.4 39 76 A R E - B 0 203A 123 -2,-0.3 2,-0.5 164,-0.2 164,-0.2 -0.983 9.8-167.9-122.8 128.9 59.8 -0.5 19.5 40 77 A Y E - B 0 202A 1 162,-3.4 162,-3.0 -2,-0.4 2,-0.1 -0.966 20.9-128.4-119.2 124.0 60.2 -1.6 15.9 41 78 A S E - B 0 201A 36 -2,-0.5 160,-0.2 160,-0.2 159,-0.1 -0.386 16.4-170.8 -63.7 142.6 60.8 0.9 13.1 42 79 A L + 0 0 0 158,-3.0 2,-0.9 4,-0.1 3,-0.5 0.239 48.4 120.9-109.1 6.5 58.5 0.6 10.1 43 80 A R S S- 0 0 91 157,-0.4 157,-0.1 1,-0.3 3,-0.1 -0.612 98.6 -26.8 -81.9 105.2 60.5 3.1 8.0 44 81 A D S S+ 0 0 120 -2,-0.9 2,-0.3 1,-0.1 -1,-0.3 0.718 130.6 69.4 64.0 20.0 61.6 1.3 4.9 45 82 A E - 0 0 61 -3,-0.5 187,-0.2 187,-0.1 -1,-0.1 -0.957 69.5-137.9-157.3 163.4 61.5 -2.1 6.6 46 83 A F - 0 0 0 185,-2.8 2,-2.3 -2,-0.3 -4,-0.1 -0.998 21.1-128.0-133.3 124.4 58.9 -4.4 7.9 47 84 A P + 0 0 0 0, 0.0 2,-0.8 0, 0.0 138,-0.1 -0.307 50.1 147.7 -79.9 60.7 59.4 -6.3 11.2 48 85 A L - 0 0 0 -2,-2.3 -2,-0.1 183,-0.1 131,-0.1 -0.861 57.0-113.6 -91.3 114.4 58.6 -9.9 10.1 49 86 A L > - 0 0 0 -2,-0.8 5,-0.5 129,-0.3 3,-0.1 -0.120 30.0-169.1 -61.6 144.2 60.9 -11.8 12.3 50 87 A T T 5S+ 0 0 0 178,-0.1 208,-3.6 3,-0.1 -1,-0.1 0.526 70.7 82.9-112.1 -12.7 63.8 -13.7 10.7 51 88 A T T 5S+ 0 0 0 206,-0.2 2,-0.3 174,-0.1 -1,-0.1 0.587 112.9 9.6 -72.9 -4.7 65.2 -15.9 13.5 52 89 A K T 5S- 0 0 15 206,-0.1 2,-0.5 -3,-0.1 208,-0.3 -0.932 97.4 -91.0-155.4 161.7 62.4 -18.3 12.5 53 90 A R T 5 - 0 0 132 -2,-0.3 2,-0.4 206,-0.2 208,-0.3 -0.718 38.6-153.2 -81.8 124.5 60.0 -18.4 9.6 54 91 A V < - 0 0 9 -2,-0.5 2,-2.2 -5,-0.5 3,-0.2 -0.800 24.6-116.3 -97.5 134.7 56.8 -16.5 10.4 55 92 A F > + 0 0 108 -2,-0.4 4,-1.9 1,-0.2 3,-0.4 -0.467 40.5 175.4 -73.3 78.8 53.7 -17.6 8.5 56 93 A W H > S+ 0 0 36 -2,-2.2 4,-2.5 1,-0.2 5,-0.3 0.858 74.1 57.7 -53.7 -42.7 53.2 -14.3 6.6 57 94 A K H > S+ 0 0 97 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.913 107.9 46.9 -65.1 -36.6 50.3 -15.6 4.5 58 95 A G H > S+ 0 0 2 -3,-0.4 4,-2.5 2,-0.2 5,-0.3 0.884 110.2 53.5 -69.1 -34.4 48.4 -16.4 7.7 59 96 A V H X S+ 0 0 0 -4,-1.9 4,-2.3 2,-0.2 -2,-0.2 0.965 115.0 40.6 -60.8 -50.3 49.2 -13.0 9.2 60 97 A L H X S+ 0 0 10 -4,-2.5 4,-2.4 2,-0.2 5,-0.2 0.932 116.8 47.6 -63.5 -48.2 47.8 -11.2 6.1 61 98 A E H X S+ 0 0 17 -4,-2.5 4,-2.1 -5,-0.3 -1,-0.2 0.912 112.4 48.7 -67.2 -43.9 44.8 -13.4 5.6 62 99 A E H X S+ 0 0 44 -4,-2.5 4,-2.4 -5,-0.2 -1,-0.2 0.918 110.9 50.8 -63.6 -43.4 43.8 -13.3 9.2 63 100 A L H X S+ 0 0 2 -4,-2.3 4,-2.4 -5,-0.3 -2,-0.2 0.916 109.8 49.8 -60.2 -39.7 44.1 -9.4 9.3 64 101 A L H X S+ 0 0 23 -4,-2.4 4,-3.0 1,-0.2 -1,-0.2 0.916 110.7 51.3 -67.2 -36.5 41.9 -9.1 6.2 65 102 A W H <>S+ 0 0 14 -4,-2.1 5,-1.6 -5,-0.2 4,-0.3 0.886 110.0 48.2 -65.7 -42.6 39.3 -11.4 7.8 66 103 A F H ><5S+ 0 0 21 -4,-2.4 3,-1.2 2,-0.2 -1,-0.2 0.904 112.0 50.6 -60.5 -44.8 39.3 -9.2 11.0 67 104 A I H 3<5S+ 0 0 4 -4,-2.4 -2,-0.2 1,-0.3 -1,-0.2 0.937 102.5 57.9 -66.7 -43.3 38.9 -6.1 8.9 68 105 A K T 3<5S- 0 0 109 -4,-3.0 -1,-0.3 -5,-0.2 -2,-0.2 0.620 113.1-122.5 -58.9 -9.5 36.0 -7.5 6.9 69 106 A G T < 5 + 0 0 11 -3,-1.2 -3,-0.2 -4,-0.3 2,-0.1 0.720 51.9 167.9 79.1 23.3 34.3 -7.9 10.3 70 107 A S < + 0 0 10 -5,-1.6 20,-0.4 1,-0.1 21,-0.4 -0.410 34.6 178.2 -84.9 144.1 33.8 -11.7 9.9 71 108 A T + 0 0 5 32,-0.3 14,-2.6 -2,-0.1 2,-0.7 0.091 55.6 108.0-123.8 13.4 32.8 -14.2 12.6 72 109 A N > - 0 0 22 12,-0.2 3,-1.2 31,-0.2 4,-0.4 -0.867 54.0-161.1 -95.9 109.2 32.7 -17.1 10.1 73 110 A A T >> S+ 0 0 42 -2,-0.7 4,-2.0 1,-0.2 3,-1.6 0.862 90.4 59.4 -54.0 -42.0 35.6 -19.6 10.6 74 111 A K H 3> S+ 0 0 132 1,-0.3 4,-1.3 2,-0.2 -1,-0.2 0.675 92.2 67.3 -66.5 -19.4 35.2 -21.1 7.1 75 112 A E H <4 S+ 0 0 67 -3,-1.2 -1,-0.3 2,-0.2 4,-0.2 0.730 112.4 33.6 -69.8 -20.8 35.8 -17.6 5.5 76 113 A L H <>>S+ 0 0 20 -3,-1.6 5,-0.9 -4,-0.4 4,-0.6 0.740 114.9 56.9-100.1 -34.0 39.4 -18.0 6.9 77 114 A S H <5S+ 0 0 41 -4,-2.0 -3,-0.2 3,-0.2 -2,-0.2 0.699 104.0 54.8 -66.0 -26.9 39.8 -21.8 6.4 78 115 A S T <5S+ 0 0 84 -4,-1.3 -1,-0.2 1,-0.2 -2,-0.1 0.766 104.4 50.8 -81.5 -31.1 39.0 -21.5 2.6 79 116 A K T 45S- 0 0 108 -4,-0.2 -2,-0.2 -5,-0.1 -1,-0.2 0.603 127.9-104.1 -82.0 -14.8 41.7 -19.0 1.9 80 117 A G T <5S+ 0 0 28 -4,-0.6 -3,-0.2 -19,-0.0 -2,-0.1 0.917 87.1 104.1 104.8 56.4 43.9 -21.5 3.7 81 118 A V < 0 0 32 -5,-0.9 -4,-0.2 -23,-0.1 -3,-0.1 0.511 360.0 360.0-134.7 -11.9 45.1 -20.9 7.3 82 119 A K 0 0 188 -6,-0.2 -5,-0.1 -9,-0.1 -6,-0.0 0.311 360.0 360.0 56.5 360.0 42.9 -23.1 9.7 83 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 84 142 A D 0 0 95 0, 0.0 -12,-0.2 0, 0.0 20,-0.0 0.000 360.0 360.0 360.0 106.4 30.6 -19.4 13.9 85 143 A L - 0 0 80 -14,-2.6 -13,-0.1 1,-0.3 -14,-0.0 0.435 360.0-128.1 -91.2 -1.7 33.3 -18.1 16.3 86 144 A G - 0 0 14 -15,-0.5 2,-2.5 1,-0.1 -1,-0.3 -0.399 68.0 -14.5 76.5-161.3 31.0 -15.6 18.1 87 145 A P S S+ 0 0 30 0, 0.0 49,-0.2 0, 0.0 -1,-0.1 -0.346 84.9 169.0 -78.5 68.2 32.0 -11.9 18.6 88 146 A V >> - 0 0 22 -2,-2.5 4,-1.7 3,-0.1 3,-0.5 -0.004 54.5 -73.0 -71.4-178.6 35.7 -12.3 17.7 89 147 A Y H 3> S+ 0 0 35 1,-0.2 4,-2.2 2,-0.2 5,-0.1 0.772 128.6 55.3 -50.5 -37.6 38.1 -9.4 17.0 90 148 A G H 3> S+ 0 0 0 -20,-0.4 4,-2.3 1,-0.2 5,-0.3 0.933 107.1 49.1 -65.2 -48.7 36.6 -8.4 13.6 91 149 A F H <> S+ 0 0 7 -3,-0.5 4,-2.2 -21,-0.4 -1,-0.2 0.854 113.7 47.6 -57.0 -37.5 33.1 -8.0 14.9 92 150 A Q H < S+ 0 0 11 -4,-1.7 4,-0.4 1,-0.2 22,-0.3 0.861 110.7 50.9 -77.6 -30.9 34.4 -5.9 17.7 93 151 A W H < S+ 0 0 0 -4,-2.2 22,-1.6 -5,-0.2 21,-1.2 0.876 125.1 26.1 -66.5 -41.3 36.6 -3.7 15.4 94 152 A R H < S+ 0 0 17 -4,-2.3 -2,-0.2 19,-0.2 -3,-0.2 0.695 135.2 28.1-100.2 -24.1 33.7 -3.0 13.0 95 153 A H S >< S- 0 0 35 -4,-2.2 3,-1.9 -5,-0.3 18,-0.2 -0.212 78.5-178.9-136.4 46.1 30.6 -3.3 15.2 96 154 A F B 3 +F 112 0B 54 16,-2.2 16,-2.6 -4,-0.4 -4,-0.1 -0.208 70.0 8.5 -54.6 127.3 31.8 -2.4 18.7 97 155 A G T 3 S+ 0 0 73 1,-0.3 -1,-0.3 14,-0.2 2,-0.2 0.441 91.8 138.4 81.2 1.1 29.1 -2.6 21.4 98 156 A A < - 0 0 20 -3,-1.9 2,-0.8 12,-0.2 -1,-0.3 -0.561 65.4-107.4 -78.3 143.0 26.5 -4.2 19.1 99 157 A E - 0 0 154 -2,-0.2 2,-0.1 -3,-0.1 -1,-0.1 -0.615 41.5-129.7 -71.8 106.7 24.4 -7.1 20.5 100 158 A Y + 0 0 49 -2,-0.8 3,-0.1 1,-0.1 -1,-0.1 -0.354 41.9 154.6 -64.3 132.8 25.9 -10.1 18.7 101 159 A R - 0 0 114 1,-0.5 2,-0.2 -2,-0.1 -1,-0.1 0.519 53.9 -12.5-118.8 -91.4 23.4 -12.6 17.0 102 160 A D - 0 0 91 1,-0.0 -1,-0.5 -16,-0.0 -31,-0.0 -0.540 51.1-122.1-106.7 174.8 24.5 -14.8 14.0 103 161 A M S S+ 0 0 60 -2,-0.2 -32,-0.3 1,-0.1 -31,-0.2 0.523 116.8 49.4 -87.2 -10.8 27.6 -14.9 11.7 104 162 A E S S+ 0 0 136 -33,-0.1 -1,-0.1 2,-0.1 -32,-0.0 0.691 86.9 113.9 -95.3 -28.4 25.1 -14.5 8.8 105 163 A S S S- 0 0 30 1,-0.1 2,-0.6 2,-0.1 -4,-0.0 -0.017 71.8-115.7 -48.6 145.7 23.3 -11.5 10.3 106 164 A D + 0 0 117 1,-0.1 -1,-0.1 2,-0.0 -2,-0.1 -0.796 32.0 177.2 -91.1 118.2 23.5 -8.1 8.6 107 165 A Y > + 0 0 18 -2,-0.6 3,-2.7 2,-0.0 -1,-0.1 0.297 16.0 154.9-109.3 8.6 25.3 -5.5 10.8 108 166 A S T 3 S- 0 0 100 1,-0.3 3,-0.1 -13,-0.0 -2,-0.0 -0.120 81.2 -5.7 -40.3 121.5 25.4 -2.4 8.6 109 167 A G T 3 S+ 0 0 89 1,-0.2 2,-0.5 2,-0.0 -1,-0.3 0.629 99.5 132.3 59.8 19.2 25.6 0.7 10.9 110 168 A Q < - 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