==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR RECEPTOR 21-JAN-03 1NQL . COMPND 2 MOLECULE: EPIDERMAL GROWTH FACTOR RECEPTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR K.M.FERGUSON,M.A.LEMMON . 660 2 28 28 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 34279.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 382 57.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 83 12.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 75 11.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 7 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 64 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 81 12.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 27 4.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 9 11 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 13 3 7 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 6 4 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A E 0 0 48 0, 0.0 2,-0.5 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0-179.7 34.2 2.7 -35.7 2 4 A K + 0 0 141 1,-0.3 32,-0.5 0, 0.0 31,-0.5 -0.792 360.0 88.4 129.8-157.8 36.7 5.4 -34.4 3 5 A K - 0 0 103 -2,-0.5 31,-2.2 30,-0.2 30,-1.8 0.917 55.4-151.9 19.5 124.9 36.4 8.2 -33.3 4 6 A V E -a 34 0A 55 29,-0.2 2,-0.3 28,-0.2 31,-0.2 -0.798 11.5-173.7-119.8 130.1 35.8 8.5 -29.6 5 7 A a E -a 35 0A 12 29,-2.5 31,-2.4 -2,-0.4 32,-0.3 -0.902 30.7-122.4-120.0 160.1 34.1 11.0 -27.4 6 8 A Q - 0 0 84 -2,-0.3 32,-0.1 29,-0.2 2,-0.1 0.822 41.5-138.7 -73.7 -31.8 34.1 11.0 -23.5 7 9 A G - 0 0 15 30,-0.2 2,-0.3 29,-0.2 32,-0.2 -0.226 16.7 -94.0 92.3 168.7 30.5 10.8 -22.7 8 10 A T - 0 0 14 30,-2.9 30,-0.5 -2,-0.1 3,-0.1 -0.884 20.1-170.8-121.9 154.8 28.5 12.7 -20.1 9 11 A S + 0 0 69 -2,-0.3 642,-1.0 28,-0.1 3,-0.1 -0.369 47.6 122.2-132.7 55.8 27.4 12.0 -16.5 10 12 A N > - 0 0 17 1,-0.3 3,-3.0 640,-0.2 632,-0.3 0.485 46.6-168.1 -87.5 2.8 25.0 14.9 -15.9 11 13 A K T 3 S- 0 0 52 1,-0.3 -1,-0.3 -3,-0.1 630,-0.1 -0.278 72.4 -26.2 27.3-118.8 22.1 12.6 -15.1 12 14 A L T 3 S+ 0 0 4 628,-0.2 -1,-0.3 -3,-0.1 629,-0.1 0.347 105.6 125.7 -92.1 4.7 19.2 15.0 -15.0 13 15 A T < - 0 0 0 -3,-3.0 2,-0.4 628,-0.1 630,-0.2 -0.346 54.9-135.3 -62.4 145.6 21.2 18.1 -14.1 14 16 A Q E -f 643 0B 20 628,-3.0 630,-1.8 637,-0.1 2,-0.9 -0.880 3.1-140.4-116.6 137.0 20.7 21.0 -16.5 15 17 A L E -f 644 0B 10 -2,-0.4 6,-0.2 628,-0.2 9,-0.2 -0.777 57.4 -61.0-102.1 100.0 23.4 23.1 -18.0 16 18 A G S S- 0 0 10 628,-2.0 628,-0.1 -2,-0.9 629,-0.1 -0.289 103.4 -12.6 64.0-151.6 22.5 26.8 -18.2 17 19 A T S > S- 0 0 77 1,-0.1 4,-2.7 626,-0.0 5,-0.2 -0.141 81.0 -94.2 -75.9 174.7 19.5 27.7 -20.4 18 20 A F H > S+ 0 0 88 1,-0.2 4,-2.4 2,-0.2 5,-0.1 0.905 130.8 48.7 -60.7 -37.8 18.0 25.2 -22.7 19 21 A E H > S+ 0 0 111 2,-0.2 4,-2.8 1,-0.2 5,-0.3 0.978 108.6 51.5 -60.6 -58.5 20.2 26.7 -25.5 20 22 A D H > S+ 0 0 45 1,-0.2 4,-1.3 2,-0.2 -2,-0.2 0.893 113.2 47.4 -42.2 -49.1 23.3 26.4 -23.3 21 23 A H H X S+ 0 0 12 -4,-2.7 4,-2.2 -6,-0.2 -1,-0.2 0.849 110.2 50.6 -64.8 -43.8 22.4 22.8 -22.7 22 24 A F H X S+ 0 0 17 -4,-2.4 4,-2.7 -5,-0.2 -1,-0.2 0.938 108.3 53.2 -60.3 -45.3 21.8 22.0 -26.4 23 25 A L H X S+ 0 0 55 -4,-2.8 4,-2.6 1,-0.2 -2,-0.2 0.804 109.8 48.9 -59.8 -30.0 25.1 23.6 -27.3 24 26 A S H X S+ 0 0 17 -4,-1.3 4,-2.0 -5,-0.3 5,-0.2 0.949 109.4 49.6 -76.0 -46.6 26.9 21.3 -24.8 25 27 A L H X S+ 0 0 16 -4,-2.2 4,-3.0 1,-0.2 3,-0.5 0.956 113.8 50.5 -52.9 -47.3 25.2 18.2 -26.0 26 28 A Q H X S+ 0 0 72 -4,-2.7 4,-2.8 1,-0.3 -2,-0.2 0.945 110.3 44.2 -57.3 -61.3 26.3 19.3 -29.4 27 29 A R H < S+ 0 0 120 -4,-2.6 -1,-0.3 1,-0.2 -2,-0.2 0.699 115.8 51.1 -62.9 -17.9 29.9 20.0 -28.7 28 30 A M H < S+ 0 0 63 -4,-2.0 -1,-0.2 -3,-0.5 -2,-0.2 0.959 122.0 27.2 -81.9 -49.3 30.2 16.7 -26.8 29 31 A F H >< S+ 0 0 2 -4,-3.0 3,-2.3 -5,-0.2 -2,-0.2 0.606 81.4 133.5 -94.0 -12.3 28.7 14.4 -29.4 30 32 A N T 3< S- 0 0 85 -4,-2.8 23,-0.0 -5,-0.3 -4,-0.0 -0.102 90.1 -11.0 -39.2 116.2 29.5 16.3 -32.7 31 33 A N T 3 S+ 0 0 100 1,-0.2 2,-0.4 21,-0.1 -1,-0.3 0.781 99.0 150.2 57.3 31.7 30.9 13.7 -35.1 32 34 A a < + 0 0 1 -3,-2.3 -1,-0.2 1,-0.1 -28,-0.2 -0.780 25.2 172.1-102.5 140.1 31.2 11.0 -32.4 33 35 A E S S+ 0 0 47 -30,-1.8 24,-2.8 -31,-0.5 25,-2.1 0.718 70.2 40.1-111.0 -38.1 30.9 7.3 -33.1 34 36 A V E -ab 4 58A 19 -31,-2.2 -29,-2.5 -32,-0.5 2,-0.8 -0.970 66.0-155.3-121.8 119.7 31.9 5.6 -29.9 35 37 A V E -ab 5 59A 0 23,-3.1 25,-2.8 -2,-0.5 26,-0.3 -0.851 2.8-167.5 -93.8 110.0 30.9 7.0 -26.5 36 38 A L S S+ 0 0 41 -31,-2.4 -29,-0.2 -2,-0.8 -30,-0.2 0.712 80.2 18.4 -60.4 -28.1 33.3 5.9 -23.8 37 39 A G S S- 0 0 19 -32,-0.3 24,-2.9 1,-0.2 23,-0.4 0.189 111.4 -44.6-116.4-128.6 30.9 7.0 -21.0 38 40 A N - 0 0 3 -30,-0.5 -30,-2.9 23,-0.2 2,-0.5 -0.782 34.5-134.3-116.8 165.0 27.2 7.7 -21.2 39 41 A L E +h 63 0C 0 23,-2.2 25,-2.6 -2,-0.3 2,-0.5 -0.958 23.1 178.4-116.6 112.0 24.8 9.4 -23.5 40 42 A E E -h 64 0C 4 -2,-0.5 2,-0.6 23,-0.2 25,-0.2 -0.968 4.3-177.6-118.8 113.4 22.3 11.6 -21.8 41 43 A I E +h 65 0C 0 23,-3.5 25,-1.5 -2,-0.5 2,-0.3 -0.956 26.8 146.0-112.3 104.0 19.9 13.5 -24.1 42 44 A T E +h 66 0C 3 -2,-0.6 25,-0.2 23,-0.2 26,-0.2 -0.978 48.9 17.2-144.1 156.3 17.6 15.7 -21.9 43 45 A Y S S+ 0 0 21 23,-0.8 25,-0.2 24,-0.5 2,-0.1 0.388 73.7 153.0 64.0 -1.9 15.7 19.0 -21.9 44 46 A V - 0 0 4 -23,-0.1 25,-3.2 1,-0.1 26,-0.9 -0.388 33.7-142.7 -61.6 131.7 16.0 19.3 -25.8 45 47 A Q - 0 0 54 24,-0.2 3,-0.4 1,-0.2 26,-0.1 -0.237 28.5 -64.7 -91.6 174.3 13.1 21.5 -27.1 46 48 A R S S+ 0 0 137 1,-0.2 -1,-0.2 24,-0.2 24,-0.2 -0.309 115.1 12.6 -53.0 141.7 10.9 21.4 -30.3 47 49 A N S S+ 0 0 153 1,-0.2 2,-0.4 22,-0.1 -1,-0.2 0.944 83.4 135.7 51.7 58.2 12.8 22.0 -33.5 48 50 A Y - 0 0 77 -3,-0.4 2,-0.7 -4,-0.1 -1,-0.2 -0.983 59.6-118.3-125.0 129.7 16.3 21.7 -32.4 49 51 A D + 0 0 105 -2,-0.4 3,-0.3 1,-0.1 24,-0.1 -0.598 33.4 175.3 -74.2 109.8 18.3 19.6 -34.8 50 52 A L + 0 0 5 -2,-0.7 3,-0.2 22,-0.3 -1,-0.1 -0.238 40.0 125.7 -99.3 45.5 19.6 16.4 -33.2 51 53 A S > + 0 0 54 1,-0.2 3,-2.3 2,-0.2 -1,-0.2 0.839 58.1 69.9 -69.9 -29.4 21.0 15.2 -36.5 52 54 A F G > S+ 0 0 26 -3,-0.3 3,-2.5 1,-0.3 -1,-0.2 0.908 84.6 67.4 -62.5 -43.6 24.5 14.8 -35.1 53 55 A L G > S+ 0 0 0 1,-0.3 3,-1.2 -3,-0.2 24,-0.4 0.551 77.8 85.1 -50.1 -5.6 23.4 11.8 -33.1 54 56 A K G < S+ 0 0 97 -3,-2.3 -1,-0.3 1,-0.2 23,-0.2 0.753 85.5 61.0 -66.9 -17.1 22.9 9.9 -36.5 55 57 A T G < S+ 0 0 43 -3,-2.5 2,-0.5 -4,-0.2 -1,-0.2 0.496 76.2 108.2 -89.4 -6.2 26.6 9.2 -36.1 56 58 A I < + 0 0 0 -3,-1.2 21,-0.3 1,-0.2 -23,-0.2 -0.616 27.9 160.5 -90.8 124.9 26.7 7.2 -32.9 57 59 A Q + 0 0 47 -24,-2.8 22,-3.6 -2,-0.5 23,-1.6 0.807 63.9 28.7-106.7 -39.3 27.4 3.5 -33.1 58 60 A E E -bc 34 80A 21 -25,-2.1 -23,-3.1 21,-0.2 2,-0.4 -0.990 54.2-172.0-128.8 133.3 28.6 2.3 -29.6 59 61 A V E -bc 35 81A 0 21,-2.0 23,-2.8 -2,-0.4 24,-0.3 -0.999 4.0-168.5-120.6 126.4 27.7 3.7 -26.2 60 62 A A S S+ 0 0 9 -25,-2.8 24,-2.8 -2,-0.4 25,-0.3 0.833 74.0 34.4 -80.1 -34.8 29.7 2.1 -23.3 61 63 A G S S- 0 0 1 -24,-2.9 22,-1.8 -26,-0.3 23,-0.3 0.571 110.0 -60.1 -91.5-118.1 27.7 3.5 -20.3 62 64 A Y - 0 0 6 21,-0.2 -23,-2.2 20,-0.1 2,-0.6 -0.839 39.2-121.5-127.9 170.8 24.0 3.9 -20.5 63 65 A V E -hi 39 93C 0 29,-2.9 31,-2.2 -2,-0.3 2,-0.5 -0.955 23.5-172.5-120.6 117.8 21.6 6.0 -22.6 64 66 A L E +hi 40 94C 0 -25,-2.6 -23,-3.5 -2,-0.6 2,-0.5 -0.952 9.5 171.4-113.1 119.4 19.3 8.4 -20.8 65 67 A I E +hi 41 95C 0 29,-2.4 31,-1.1 -2,-0.5 2,-0.3 -0.946 26.9 138.9-129.2 102.8 16.6 10.2 -22.9 66 68 A A E +hi 42 96C 0 -25,-1.5 -23,-0.8 -2,-0.5 31,-0.2 -0.992 48.8 19.2-150.3 151.9 14.3 12.1 -20.6 67 69 A L S S+ 0 0 29 30,-2.3 -24,-0.5 29,-1.4 2,-0.3 0.800 80.9 144.4 58.2 38.5 12.5 15.4 -20.3 68 70 A N - 0 0 0 29,-0.3 38,-0.4 28,-0.2 -1,-0.2 -0.704 42.1-166.8-103.2 156.0 12.6 16.2 -24.0 69 71 A T + 0 0 16 -25,-3.2 -24,-0.2 -2,-0.3 -22,-0.1 0.350 51.7 121.8-114.6 -2.0 10.1 18.0 -26.3 70 72 A V - 0 0 5 -26,-0.9 -24,-0.2 -24,-0.2 3,-0.1 -0.359 58.3-145.3 -62.3 140.0 11.8 17.0 -29.6 71 73 A E S S+ 0 0 113 35,-0.2 37,-3.4 1,-0.2 36,-2.7 0.826 82.2 36.3 -67.6 -30.8 9.6 15.0 -31.9 72 74 A R B -m 108 0D 93 35,-0.2 -22,-0.3 34,-0.2 -1,-0.2 -0.973 50.6-175.8-141.6 119.0 12.5 13.0 -33.2 73 75 A I - 0 0 0 35,-2.8 2,-1.8 -2,-0.4 -22,-0.1 -0.918 19.5-155.3-116.1 107.0 15.8 11.5 -31.8 74 76 A P + 0 0 7 0, 0.0 2,-2.6 0, 0.0 3,-0.3 -0.336 33.5 153.5 -84.8 57.3 17.8 9.9 -34.6 75 77 A L > + 0 0 0 -2,-1.8 3,-1.1 1,-0.2 38,-0.3 -0.229 25.0 151.1 -71.8 55.3 19.9 7.3 -32.8 76 78 A E T 3 + 0 0 7 -2,-2.6 37,-0.3 1,-0.3 -1,-0.2 0.678 65.9 30.8 -74.4 -24.4 19.8 5.6 -36.2 77 79 A N T 3 S+ 0 0 66 -24,-0.4 2,-0.4 -3,-0.3 -1,-0.3 0.283 77.3 136.6-116.7 14.1 23.0 3.7 -36.2 78 80 A L < + 0 0 0 -3,-1.1 -21,-0.2 1,-0.2 -20,-0.2 -0.469 25.7 173.5 -60.8 116.1 23.3 3.1 -32.5 79 81 A Q + 0 0 24 -22,-3.6 36,-2.4 -2,-0.4 37,-1.0 0.869 53.5 11.1-101.1 -45.6 24.4 -0.5 -32.6 80 82 A I E -cd 58 116A 0 -23,-1.6 -21,-2.0 34,-0.2 2,-0.5 -0.984 46.9-161.6-136.2 145.3 25.2 -1.5 -29.0 81 83 A I E -cd 59 117A 0 35,-2.3 37,-2.1 -2,-0.3 38,-0.4 -0.994 11.8-166.5-118.1 119.1 24.7 -0.1 -25.6 82 84 A R - 0 0 13 -23,-2.8 37,-0.3 -2,-0.5 -22,-0.2 0.819 16.5-146.3 -79.7 -28.1 27.1 -1.9 -23.3 83 85 A G + 0 0 3 -22,-1.8 -22,-0.2 -24,-0.3 -21,-0.2 0.935 40.2 154.3 63.8 45.2 25.6 -0.8 -19.9 84 86 A N S S+ 0 0 107 -24,-2.8 2,-0.3 -23,-0.3 -23,-0.2 0.648 76.2 31.6 -75.4 -17.6 29.0 -0.7 -18.1 85 87 A M S S- 0 0 121 -25,-0.3 -1,-0.2 34,-0.1 2,-0.2 -0.988 87.2-140.6-133.9 133.2 27.3 1.9 -15.9 86 88 A Y - 0 0 83 -2,-0.3 2,-0.5 -3,-0.1 3,-0.3 -0.551 9.5-127.8 -88.8 154.3 23.6 1.8 -15.0 87 89 A Y B >> S-J 91 0C 7 4,-3.1 4,-2.5 1,-0.2 3,-1.7 -0.903 91.1 -2.2 -91.8 132.5 21.1 4.6 -14.7 88 90 A E T 34 S- 0 0 60 -2,-0.5 -1,-0.2 1,-0.3 3,-0.0 0.917 130.7 -58.2 55.9 48.1 19.1 4.5 -11.4 89 91 A N T 34 S+ 0 0 155 -3,-0.3 -1,-0.3 1,-0.2 -3,-0.1 0.310 133.4 21.7 72.5 -6.5 20.7 1.3 -10.2 90 92 A S T <4 S+ 0 0 31 -3,-1.7 31,-2.7 1,-0.2 2,-0.5 0.499 85.6 99.7-164.4 -21.8 19.7 -0.9 -13.1 91 93 A Y E < -Jk 87 121C 36 -4,-2.5 -4,-3.1 29,-0.2 3,-0.2 -0.745 30.9-178.2 -93.5 130.4 18.8 0.6 -16.5 92 94 A A E S+ 0 0 0 29,-2.5 -29,-2.9 -2,-0.5 2,-0.4 0.779 89.1 30.6 -85.9 -28.0 21.1 0.7 -19.4 93 95 A L E S+ik 63 122C 0 28,-1.7 30,-2.7 -31,-0.2 2,-0.5 -0.905 70.5 174.1-135.4 111.4 18.5 2.4 -21.4 94 96 A A E -ik 64 123C 0 -31,-2.2 -29,-2.4 -2,-0.4 2,-0.6 -0.949 7.7-179.2-118.4 124.6 15.9 4.7 -19.7 95 97 A V E +ik 65 124C 0 28,-3.5 30,-1.7 -2,-0.5 2,-0.5 -0.835 22.3 171.0-129.6 91.0 13.5 6.7 -21.8 96 98 A L E -ik 66 125C 0 -31,-1.1 -29,-1.4 -2,-0.6 30,-0.2 -0.886 46.9 -21.5-118.0 121.4 11.5 8.7 -19.3 97 99 A S + 0 0 4 28,-3.8 -30,-2.3 -2,-0.5 2,-0.4 0.945 56.0 173.6 53.3 81.6 8.9 11.4 -19.7 98 100 A N + 0 0 0 28,-1.4 8,-1.5 -31,-0.2 2,-0.2 -0.602 46.2 83.8-120.9 72.1 9.5 13.1 -23.0 99 101 A Y - 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