==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=9-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 27-NOV-02 1O8E . COMPND 2 MOLECULE: PECTATE LYASE C; . SOURCE 2 ORGANISM_SCIENTIFIC: ERWINIA CHRYSANTHEMI; . AUTHOR S.R.HERRON,F.A.JURNAK . 352 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13237.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 261 74.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 115 32.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 7 2.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 50 14.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 28 8.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 24 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 3 4 6 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 132 0, 0.0 9,-0.0 0, 0.0 8,-0.0 0.000 360.0 360.0 360.0 163.3 17.8 44.0 -23.2 2 2 A T + 0 0 67 9,-0.1 8,-1.6 7,-0.1 2,-0.4 0.153 360.0 140.4-112.1 9.3 18.1 42.1 -19.9 3 3 A D B +A 9 0A 112 6,-0.2 6,-0.1 1,-0.2 5,-0.0 -0.466 12.6 157.4 -64.6 117.9 14.8 40.2 -20.3 4 4 A T - 0 0 6 4,-0.5 -1,-0.2 -2,-0.4 3,-0.1 0.523 58.4-112.6-115.4 -16.4 15.1 36.6 -19.2 5 5 A G S S+ 0 0 12 1,-0.4 2,-0.2 3,-0.2 4,-0.1 0.493 91.6 55.0 91.1 7.7 11.4 35.9 -18.4 6 6 A G S S- 0 0 3 2,-0.5 -1,-0.4 200,-0.1 -2,-0.4 -0.759 109.4 -59.0-149.7-167.0 12.2 35.6 -14.8 7 7 A Y S S+ 0 0 29 171,-0.5 172,-0.2 -2,-0.2 198,-0.1 0.864 102.9 85.2 -54.5 -43.1 13.7 37.3 -11.7 8 8 A A - 0 0 2 133,-0.2 2,-0.5 198,-0.1 -4,-0.5 -0.350 58.3-166.4 -66.0 135.2 17.2 37.7 -13.2 9 9 A A B +A 3 0A 45 -6,-0.1 2,-0.3 168,-0.1 -6,-0.2 -0.915 37.0 121.3-124.4 101.6 17.7 40.8 -15.4 10 10 A T - 0 0 2 -8,-1.6 3,-0.1 -2,-0.5 130,-0.0 -0.993 52.7-158.0-162.9 153.2 20.9 40.5 -17.3 11 11 A A > - 0 0 26 1,-0.3 3,-2.2 -2,-0.3 2,-0.1 0.257 41.2-151.6-112.3 6.8 22.6 40.4 -20.7 12 12 A G T 3 - 0 0 2 1,-0.3 -1,-0.3 128,-0.2 80,-0.3 -0.359 69.1 -17.0 59.7-127.3 25.7 38.5 -19.4 13 13 A G T 3 S+ 0 0 0 77,-0.2 2,-1.8 1,-0.2 -1,-0.3 0.464 112.6 99.8 -89.3 -1.7 28.7 39.3 -21.4 14 14 A N < + 0 0 121 -3,-2.2 2,-0.2 77,-0.1 -1,-0.2 -0.334 63.2 105.2 -83.7 60.1 26.7 40.6 -24.3 15 15 A V S > S- 0 0 65 -2,-1.8 3,-1.1 75,-0.1 -2,-0.0 -0.637 79.1 -53.4-126.6-178.4 27.3 44.3 -23.3 16 16 A T T 3 S+ 0 0 138 1,-0.2 -1,-0.1 -2,-0.2 -2,-0.0 -0.318 119.4 13.1 -64.2 137.8 29.3 47.3 -24.4 17 17 A G T 3 S+ 0 0 60 1,-0.2 -1,-0.2 33,-0.1 2,-0.2 0.758 88.8 162.5 69.7 27.7 33.0 46.8 -24.7 18 18 A A < - 0 0 39 -3,-1.1 2,-0.4 32,-0.1 34,-0.2 -0.552 35.0-132.8 -83.3 144.0 32.8 43.0 -24.6 19 19 A V E -b 52 0B 44 32,-3.2 34,-2.0 -2,-0.2 2,-0.6 -0.816 14.6-144.6 -97.1 128.2 35.6 40.7 -25.7 20 20 A S E +b 53 0B 96 -2,-0.4 2,-0.3 32,-0.2 34,-0.2 -0.882 24.5 172.4 -99.3 117.5 34.6 37.8 -28.0 21 21 A K E -b 54 0B 97 32,-2.0 34,-2.6 -2,-0.6 2,-0.5 -0.947 24.5-143.6-125.9 141.5 36.6 34.6 -27.5 22 22 A T E -b 55 0B 90 -2,-0.3 2,-0.6 32,-0.2 34,-0.2 -0.944 14.8-156.6-106.6 121.1 36.1 31.1 -28.9 23 23 A A E -b 56 0B 0 32,-2.3 34,-2.7 -2,-0.5 35,-0.9 -0.891 13.4-175.9-103.1 118.7 36.9 28.2 -26.6 24 24 A T S S+ 0 0 83 -2,-0.6 35,-0.3 33,-0.2 2,-0.3 0.461 72.5 9.4 -89.9 -2.4 37.8 24.9 -28.2 25 25 A S S > S- 0 0 39 33,-0.2 4,-1.3 1,-0.1 5,-0.1 -0.950 85.3 -92.8-162.3 174.2 38.1 23.0 -24.9 26 26 A M H > S+ 0 0 28 -2,-0.3 4,-2.2 1,-0.2 3,-0.4 0.906 125.7 53.5 -64.0 -43.0 37.4 23.3 -21.2 27 27 A Q H > S+ 0 0 102 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.839 103.0 58.2 -61.5 -32.7 41.0 24.5 -20.8 28 28 A D H > S+ 0 0 49 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.861 106.5 47.3 -64.8 -36.5 40.3 27.2 -23.4 29 29 A I H X S+ 0 0 0 -4,-1.3 4,-2.1 -3,-0.4 5,-0.2 0.929 111.9 51.0 -68.8 -44.0 37.5 28.6 -21.3 30 30 A V H X S+ 0 0 49 -4,-2.2 4,-1.5 1,-0.2 -2,-0.2 0.903 112.4 46.2 -59.6 -44.2 39.7 28.5 -18.2 31 31 A N H X S+ 0 0 88 -4,-2.5 4,-1.9 2,-0.2 -1,-0.2 0.827 110.1 52.7 -68.1 -36.7 42.5 30.4 -19.9 32 32 A I H X S+ 0 0 24 -4,-1.7 4,-1.9 2,-0.2 -2,-0.2 0.897 110.7 47.5 -67.0 -41.3 40.2 33.0 -21.5 33 33 A I H < S+ 0 0 7 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.841 112.1 50.1 -70.6 -32.1 38.7 33.9 -18.1 34 34 A D H >< S+ 0 0 97 -4,-1.5 3,-1.1 -5,-0.2 4,-0.2 0.854 110.3 48.0 -74.6 -36.5 42.1 34.1 -16.5 35 35 A A H >< S+ 0 0 50 -4,-1.9 3,-2.0 1,-0.2 -2,-0.2 0.885 102.6 66.5 -68.1 -35.3 43.5 36.4 -19.1 36 36 A A T 3< S+ 0 0 0 -4,-1.9 13,-3.2 1,-0.3 14,-0.6 0.478 90.0 66.1 -64.4 -3.9 40.3 38.4 -18.7 37 37 A R T < S+ 0 0 49 -3,-1.1 8,-3.2 11,-0.2 -1,-0.3 0.628 91.5 73.1 -94.2 -13.3 41.4 39.3 -15.2 38 38 A L B < -K 44 0C 54 -3,-2.0 6,-0.2 6,-0.3 11,-0.1 -0.695 69.2-142.0-104.7 151.8 44.4 41.4 -16.3 39 39 A D > - 0 0 59 4,-2.2 3,-1.0 -2,-0.3 -1,-0.1 -0.146 49.0 -71.3 -93.4-164.8 44.6 44.8 -17.9 40 40 A A T 3 S+ 0 0 107 1,-0.2 -2,-0.0 2,-0.1 -1,-0.0 0.792 134.7 46.9 -59.5 -31.6 46.9 46.1 -20.6 41 41 A N T 3 S- 0 0 123 2,-0.1 -1,-0.2 3,-0.0 3,-0.1 0.541 120.7-104.4 -86.8 -14.0 49.9 46.1 -18.2 42 42 A G S < S+ 0 0 47 -3,-1.0 2,-0.4 1,-0.3 -2,-0.1 0.620 76.6 138.3 97.3 12.2 49.2 42.6 -16.9 43 43 A K - 0 0 140 1,-0.1 -4,-2.2 0, 0.0 -1,-0.3 -0.789 58.4-106.9 -93.7 137.8 47.8 43.9 -13.6 44 44 A K B -K 38 0C 170 -2,-0.4 2,-0.5 -6,-0.2 -6,-0.3 -0.386 25.8-154.3 -67.3 133.7 44.7 42.3 -12.1 45 45 A V > - 0 0 51 -8,-3.2 3,-2.0 -2,-0.1 5,-0.1 -0.946 26.2-114.0-111.3 124.2 41.3 44.2 -12.3 46 46 A K T 3 S+ 0 0 155 -2,-0.5 41,-0.1 1,-0.3 40,-0.1 -0.340 99.8 11.5 -59.1 128.2 38.8 43.3 -9.6 47 47 A G B 3 S-l 87 0D 2 39,-0.5 42,-1.7 -2,-0.1 41,-1.1 0.440 135.4 -57.1 81.7 2.5 35.7 41.6 -11.1 48 48 A G < - 0 0 0 -3,-2.0 -11,-0.2 -11,-0.2 -12,-0.1 -0.146 48.5-107.5 104.5 154.3 37.4 41.1 -14.4 49 49 A A S S- 0 0 25 -13,-3.2 -12,-0.1 1,-0.2 -1,-0.1 0.735 93.3 -3.5 -89.4 -24.3 39.0 43.7 -16.7 50 50 A Y S S- 0 0 61 -14,-0.6 -1,-0.2 -5,-0.1 39,-0.2 -0.952 84.5 -79.0-160.3 166.9 36.3 43.6 -19.4 51 51 A P - 0 0 12 0, 0.0 -32,-3.2 0, 0.0 2,-0.4 -0.500 45.7-147.8 -74.7 147.5 33.0 41.8 -20.4 52 52 A L E -bc 19 91B 0 38,-2.4 40,-2.3 -34,-0.2 2,-0.4 -0.927 24.2-178.2-126.3 143.5 33.3 38.3 -22.0 53 53 A V E -bc 20 92B 17 -34,-2.0 -32,-2.0 -2,-0.4 2,-0.5 -0.922 19.2-171.4-135.3 99.3 31.3 36.3 -24.5 54 54 A I E -bc 21 93B 0 38,-3.1 40,-2.7 -2,-0.4 2,-0.7 -0.884 10.7-157.3 -99.9 122.5 32.9 32.9 -24.8 55 55 A T E -bc 22 94B 45 -34,-2.6 -32,-2.3 -2,-0.5 2,-0.7 -0.898 12.5-150.4-100.2 108.8 31.7 30.6 -27.6 56 56 A Y E +bc 23 95B 1 38,-2.5 40,-2.9 -2,-0.7 -32,-0.2 -0.740 25.1 167.6 -84.4 115.7 32.5 27.0 -26.7 57 57 A T + 0 0 63 -34,-2.7 -33,-0.2 -2,-0.7 -1,-0.1 0.293 37.1 119.1-109.1 7.4 33.1 24.9 -29.8 58 58 A G - 0 0 5 -35,-0.9 42,-1.5 -33,-0.1 2,-0.4 -0.268 47.4-154.7 -72.2 161.2 34.6 21.9 -28.0 59 59 A N B +m 100 0E 82 -35,-0.3 3,-0.2 40,-0.3 42,-0.2 -0.956 18.7 173.7-141.3 120.3 33.0 18.4 -28.1 60 60 A E >> + 0 0 27 40,-1.0 4,-1.5 -2,-0.4 3,-0.6 -0.167 32.7 133.1-118.4 39.1 33.5 15.8 -25.4 61 61 A D H 3> + 0 0 47 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.802 67.7 61.1 -59.4 -32.1 31.1 13.1 -26.7 62 62 A S H 3> S+ 0 0 97 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.899 108.1 44.7 -61.5 -42.0 33.6 10.3 -26.3 63 63 A L H <> S+ 0 0 78 -3,-0.6 4,-1.9 2,-0.2 -1,-0.2 0.823 113.1 49.0 -71.5 -36.6 33.8 11.0 -22.6 64 64 A I H X S+ 0 0 2 -4,-1.5 4,-1.8 2,-0.2 -2,-0.2 0.888 113.7 47.3 -71.0 -38.2 30.0 11.4 -22.2 65 65 A N H X S+ 0 0 100 -4,-2.7 4,-1.9 2,-0.2 -2,-0.2 0.925 112.2 50.5 -67.8 -41.7 29.5 8.1 -24.0 66 66 A A H X S+ 0 0 56 -4,-2.3 4,-0.6 -5,-0.2 -2,-0.2 0.885 110.9 48.8 -64.0 -38.3 32.2 6.4 -21.9 67 67 A A H < S+ 0 0 1 -4,-1.9 3,-0.4 1,-0.2 -1,-0.2 0.818 110.0 50.4 -70.7 -34.6 30.5 7.7 -18.7 68 68 A A H >< S+ 0 0 40 -4,-1.8 3,-0.7 1,-0.2 -1,-0.2 0.814 104.1 60.9 -71.7 -30.8 27.1 6.4 -19.9 69 69 A A H 3< S+ 0 0 87 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.671 124.6 16.0 -69.2 -20.6 28.8 3.0 -20.6 70 70 A N T >< S+ 0 0 106 -4,-0.6 3,-1.8 -3,-0.4 4,-0.3 -0.428 73.2 170.8-153.5 70.7 29.8 2.6 -16.9 71 71 A I G X S+ 0 0 31 -3,-0.7 3,-1.0 1,-0.3 4,-0.4 0.707 74.5 60.3 -59.1 -26.7 27.8 5.1 -14.9 72 72 A a G 3 S+ 0 0 50 1,-0.2 4,-0.3 2,-0.2 -1,-0.3 0.668 95.0 64.3 -78.9 -13.3 28.8 3.8 -11.5 73 73 A G G <> S+ 0 0 17 -3,-1.8 4,-0.6 -6,-0.2 -1,-0.2 0.563 88.0 75.5 -82.9 -7.1 32.4 4.5 -12.3 74 74 A Q T X4 S+ 0 0 4 -3,-1.0 51,-2.5 -4,-0.3 3,-0.8 0.889 80.8 63.0 -72.1 -42.1 31.6 8.2 -12.4 75 75 A W T 34 S+ 0 0 65 -4,-0.4 52,-1.4 -3,-0.2 53,-0.3 0.823 103.2 48.1 -55.7 -38.0 31.3 9.0 -8.7 76 76 A S T 34 S+ 0 0 63 -4,-0.3 -1,-0.2 -3,-0.1 -2,-0.2 0.694 93.2 93.9 -77.9 -24.5 34.9 8.2 -7.8 77 77 A K S << S- 0 0 108 -3,-0.8 50,-0.2 -4,-0.6 51,-0.2 -0.095 90.6 -82.7 -64.4 167.7 36.6 10.2 -10.7 78 78 A D - 0 0 128 46,-0.1 -1,-0.1 1,-0.1 2,-0.1 -0.526 47.4-119.5 -72.5 135.1 37.8 13.8 -10.4 79 79 A P - 0 0 37 0, 0.0 2,-0.4 0, 0.0 46,-0.2 -0.471 27.7-150.0 -74.5 150.1 35.0 16.3 -10.8 80 80 A R + 0 0 65 44,-0.5 24,-2.5 22,-0.1 2,-0.3 -0.975 28.1 135.3-124.6 140.1 35.5 18.8 -13.8 81 81 A G E -n 104 0F 13 -2,-0.4 2,-0.7 22,-0.3 24,-0.2 -0.962 49.6-114.2-177.0 155.7 34.3 22.3 -14.1 82 82 A V E -n 105 0F 1 22,-2.2 24,-3.2 -2,-0.3 2,-0.4 -0.888 34.7-148.5 -98.3 111.4 34.9 25.9 -15.1 83 83 A E E -n 106 0F 100 -2,-0.7 2,-0.6 22,-0.2 24,-0.2 -0.690 10.3-165.6 -84.5 131.6 34.8 28.1 -12.1 84 84 A I E +n 107 0F 0 22,-2.9 24,-1.9 -2,-0.4 2,-0.4 -0.786 24.7 172.6-114.4 78.0 33.5 31.6 -12.7 85 85 A K E -n 108 0F 64 -2,-0.6 24,-0.2 1,-0.2 25,-0.1 -0.797 59.6 -14.2 -96.2 133.6 34.6 33.2 -9.4 86 86 A E S S+ 0 0 61 22,-2.0 2,-0.6 -2,-0.4 -39,-0.5 0.886 85.1 144.1 44.5 49.2 34.3 36.9 -8.6 87 87 A F B +l 47 0D 0 -3,-0.4 24,-1.2 21,-0.2 -1,-0.2 -0.943 9.8 157.6-117.9 105.4 33.7 37.9 -12.2 88 88 A T + 0 0 63 -41,-1.1 -40,-0.2 -2,-0.6 -1,-0.1 0.415 46.7 89.4-110.9 1.0 31.3 40.8 -12.2 89 89 A K S S- 0 0 109 -42,-1.7 -1,-0.1 -39,-0.2 -41,-0.1 0.602 105.8 -87.2 -74.9 -11.2 31.9 42.5 -15.6 90 90 A G - 0 0 2 21,-0.5 -38,-2.4 -3,-0.1 2,-0.3 0.365 51.1-168.3 104.8 117.7 29.3 40.4 -17.4 91 91 A I E -cd 52 113B 0 21,-2.2 23,-2.0 -40,-0.2 2,-0.4 -1.000 9.7-164.6-143.2 138.4 30.2 37.1 -19.0 92 92 A T E -cd 53 114B 8 -40,-2.3 -38,-3.1 -2,-0.3 2,-0.7 -0.991 0.9-168.3-126.4 123.1 28.3 34.8 -21.3 93 93 A I E +cd 54 115B 0 21,-3.0 23,-2.0 -2,-0.4 2,-0.4 -0.942 18.8 172.7-111.1 106.3 29.3 31.2 -21.9 94 94 A I E -cd 55 116B 38 -40,-2.7 -38,-2.5 -2,-0.7 23,-0.2 -0.965 25.7-135.5-121.0 130.9 27.5 29.8 -24.9 95 95 A G E -c 56 0B 1 21,-2.3 -38,-0.2 -2,-0.4 2,-0.2 -0.559 22.7-122.8 -80.8 145.1 28.0 26.5 -26.6 96 96 A A > - 0 0 28 -40,-2.9 3,-2.6 -2,-0.2 2,-0.1 -0.536 45.8 -82.4 -80.0 153.1 28.1 26.3 -30.4 97 97 A N T 3 S+ 0 0 93 1,-0.3 -1,-0.1 -2,-0.2 3,-0.1 -0.419 123.5 24.8 -58.1 127.7 25.6 24.0 -32.0 98 98 A G T 3 S+ 0 0 67 1,-0.4 -1,-0.3 -2,-0.1 2,-0.1 0.219 93.4 127.9 100.2 -13.9 27.1 20.6 -31.9 99 99 A S < - 0 0 9 -3,-2.6 -1,-0.4 18,-0.2 2,-0.3 -0.384 34.6-175.7 -75.7 153.2 29.3 21.3 -28.8 100 100 A S B -m 59 0E 1 -42,-1.5 -40,-1.0 18,-0.1 2,-0.4 -0.989 9.6-154.0-151.0 148.4 29.2 19.1 -25.8 101 101 A A B -v 120 0G 0 18,-3.1 20,-1.7 -2,-0.3 22,-0.0 -0.960 22.3-172.8-132.9 142.1 30.8 19.0 -22.3 102 102 A N S S+ 0 0 9 -2,-0.4 2,-0.3 18,-0.2 -22,-0.1 -0.200 80.6 72.0-115.6 30.3 31.7 16.4 -19.8 103 103 A F S S- 0 0 0 20,-0.1 -22,-0.3 -24,-0.1 2,-0.2 -0.948 76.1-133.0-139.8 155.9 32.5 19.2 -17.4 104 104 A G E -n 81 0F 0 -24,-2.5 -22,-2.2 -2,-0.3 2,-0.5 -0.538 15.8-113.9-108.0 177.9 30.2 21.6 -15.5 105 105 A I E -no 82 133F 0 27,-2.8 29,-1.7 -24,-0.2 2,-0.6 -0.960 24.4-161.9-113.5 127.8 30.1 25.3 -14.9 106 106 A W E -no 83 134F 37 -24,-3.2 -22,-2.9 -2,-0.5 2,-0.5 -0.877 1.9-165.7-117.6 104.5 30.6 26.6 -11.4 107 107 A I E +no 84 135F 1 27,-3.1 29,-2.1 -2,-0.6 2,-0.4 -0.749 13.8 173.8 -90.2 120.3 29.5 30.1 -10.7 108 108 A K E -no 85 136F 51 -24,-1.9 -22,-2.0 -2,-0.5 -21,-0.2 -0.978 62.1 -20.8-135.1 122.7 30.7 31.5 -7.4 109 109 A K S S+ 0 0 81 27,-2.3 2,-0.2 -2,-0.4 29,-0.2 0.866 102.3 120.2 50.5 45.4 30.4 35.1 -6.0 110 110 A S - 0 0 3 26,-0.4 2,-0.3 -24,-0.2 -22,-0.2 -0.572 46.9-152.3-122.8-175.1 29.7 36.5 -9.4 111 111 A S + 0 0 28 -24,-1.2 -21,-0.5 27,-0.2 29,-0.2 -0.957 66.7 33.1-161.3 150.5 26.9 38.5 -11.1 112 112 A D S S+ 0 0 49 27,-1.1 -21,-2.2 28,-0.5 2,-0.4 0.966 73.3 157.0 61.6 59.2 25.6 38.9 -14.6 113 113 A V E -de 91 141B 0 27,-1.1 29,-3.2 26,-0.2 2,-0.4 -0.941 22.0-171.5-117.4 132.2 26.4 35.4 -15.9 114 114 A V E -de 92 142B 3 -23,-2.0 -21,-3.0 -2,-0.4 2,-0.5 -0.992 4.0-174.3-125.3 129.2 24.6 33.7 -18.8 115 115 A V E +de 93 143B 0 27,-2.8 29,-2.7 -2,-0.4 2,-0.3 -0.987 20.1 164.1-123.5 115.3 25.1 30.0 -19.8 116 116 A Q E +de 94 144B 24 -23,-2.0 -21,-2.3 -2,-0.5 29,-0.2 -0.938 49.3 11.0-133.5 157.5 23.3 29.0 -23.0 117 117 A N S S+ 0 0 4 27,-0.7 2,-0.5 28,-0.6 29,-0.2 0.750 78.5 145.5 48.9 38.8 23.3 26.2 -25.5 118 118 A M - 0 0 1 26,-0.2 29,-2.6 -25,-0.1 2,-0.8 -0.893 39.2-155.0-107.9 127.5 25.5 23.8 -23.5 119 119 A R E + w 0 147G 61 -2,-0.5 -18,-3.1 -20,-0.3 2,-0.5 -0.887 22.1 176.1-101.7 101.2 25.0 20.0 -23.6 120 120 A I E +vw 101 148G 0 27,-2.8 29,-2.3 -2,-0.8 2,-0.3 -0.945 7.3 166.6-110.7 120.8 26.4 18.8 -20.2 121 121 A G E - w 0 149G 0 -20,-1.7 29,-0.3 -2,-0.5 -54,-0.1 -0.993 46.8 -2.9-143.3 149.6 26.0 15.0 -19.4 122 122 A Y S S- 0 0 47 27,-2.0 28,-0.1 -2,-0.3 -1,-0.1 0.876 73.0-160.3 43.9 61.8 27.2 12.2 -17.1 123 123 A L - 0 0 6 26,-0.3 43,-0.2 7,-0.1 3,-0.2 -0.415 10.5-125.6 -76.3 140.9 29.7 14.2 -15.1 124 124 A P S S+ 0 0 9 0, 0.0 -44,-0.5 0, 0.0 -49,-0.2 -0.319 83.4 48.0 -76.7 160.1 32.5 12.6 -13.0 125 125 A G > > + 0 0 0 -51,-2.5 5,-2.0 -46,-0.2 3,-0.8 0.863 49.6 154.8 79.4 38.6 32.9 13.4 -9.4 126 126 A G G > 5S+ 0 0 0 38,-0.4 3,-0.6 1,-0.2 39,-0.2 0.778 80.8 52.9 -65.9 -25.6 29.4 13.0 -7.9 127 127 A A G 3 5S+ 0 0 34 -52,-1.4 -1,-0.2 1,-0.2 -51,-0.1 0.647 114.4 42.5 -82.8 -14.3 31.1 12.2 -4.6 128 128 A K G < 5S- 0 0 104 -3,-0.8 -1,-0.2 -53,-0.3 -2,-0.1 -0.321 126.0 -83.3-129.1 48.3 33.1 15.5 -4.8 129 129 A D T < 5 + 0 0 88 -3,-0.6 2,-1.7 1,-0.2 -3,-0.2 0.839 59.9 165.8 58.2 45.5 30.7 18.2 -6.1 130 130 A G < + 0 0 1 -5,-2.0 36,-0.5 -7,-0.1 -1,-0.2 -0.365 19.5 173.2 -86.3 57.3 30.8 17.6 -9.9 131 131 A D - 0 0 0 -2,-1.7 3,-0.2 1,-0.1 37,-0.2 -0.296 35.8-139.8 -63.2 152.4 27.7 19.7 -10.4 132 132 A M S S+ 0 0 5 35,-2.3 -27,-2.8 1,-0.4 2,-0.4 0.893 90.7 3.3 -79.3 -45.9 26.7 20.5 -14.0 133 133 A I E S-o 105 0F 0 35,-0.3 37,-1.6 34,-0.3 -1,-0.4 -0.987 72.7-176.5-141.4 132.3 25.7 24.1 -13.2 134 134 A R E -op 106 170F 46 -29,-1.7 -27,-3.1 -2,-0.4 2,-0.5 -0.995 7.2-172.2-133.8 134.9 26.2 25.6 -9.8 135 135 A V E +op 107 171F 0 35,-2.1 37,-2.8 -2,-0.4 2,-0.4 -0.978 14.3 168.1-128.0 113.6 25.2 29.2 -8.8 136 136 A D E S-op 108 172F 22 -29,-2.1 -27,-2.3 -2,-0.5 -26,-0.4 -0.994 70.2 -13.5-132.7 126.7 26.4 30.3 -5.4 137 137 A D S S+ 0 0 52 35,-2.0 38,-0.2 -2,-0.4 36,-0.1 0.809 101.5 129.6 56.2 30.5 26.2 33.8 -4.1 138 138 A S - 0 0 0 34,-0.5 3,-0.3 -29,-0.2 -27,-0.2 -0.887 38.0-172.0-125.6 102.0 25.5 34.9 -7.6 139 139 A P + 0 0 34 0, 0.0 -27,-1.1 0, 0.0 -26,-0.2 -0.483 67.8 32.9 -84.2 162.1 22.6 37.2 -8.5 140 140 A N S S+ 0 0 44 37,-1.5 -27,-1.1 1,-0.2 -28,-0.5 0.937 79.7 152.6 58.2 52.1 21.5 38.0 -12.0 141 141 A V E -ef 113 178B 0 36,-1.2 38,-2.0 -3,-0.3 2,-0.5 -0.918 30.3-160.1-113.4 136.5 22.4 34.6 -13.5 142 142 A W E -ef 114 179B 42 -29,-3.2 -27,-2.8 -2,-0.4 2,-0.8 -0.969 8.5-176.0-121.1 113.6 20.7 33.1 -16.5 143 143 A V E +ef 115 180B 0 36,-2.4 38,-2.3 -2,-0.5 2,-0.4 -0.922 30.1 164.8-104.9 99.8 20.9 29.4 -17.1 144 144 A D E -ef 116 181B 3 -29,-2.7 -27,-0.7 -2,-0.8 38,-0.2 -0.969 44.4 -3.3-133.2 137.2 19.1 29.1 -20.4 145 145 A H S S+ 0 0 0 36,-2.1 -28,-0.6 -2,-0.4 2,-0.3 0.856 83.1 140.2 59.3 44.8 18.7 26.5 -23.3 146 146 A N - 0 0 0 35,-0.3 38,-2.7 -29,-0.2 2,-0.6 -0.724 49.9-134.3-113.5 158.7 21.1 23.9 -22.0 147 147 A E E -wx 119 184G 28 -29,-2.6 -27,-2.8 -2,-0.3 2,-0.5 -0.977 25.8-178.6-114.1 112.3 20.7 20.1 -22.0 148 148 A L E +wx 120 185G 0 36,-2.2 38,-1.2 -2,-0.6 2,-0.3 -0.961 18.5 146.5-116.6 116.2 21.7 18.7 -18.6 149 149 A F E +wx 121 186G 12 -29,-2.3 -27,-2.0 -2,-0.5 -26,-0.3 -0.919 15.0 140.4-146.3 169.7 21.5 14.9 -18.3 150 150 A A - 0 0 6 36,-1.1 2,-0.4 37,-0.7 38,-0.1 -0.706 63.6 -50.3-171.6-138.1 22.9 11.7 -16.8 151 151 A A - 0 0 17 -2,-0.2 2,-2.8 2,-0.2 38,-0.5 -0.991 36.7-136.6-124.6 125.4 21.3 8.6 -15.4 152 152 A N S S+ 0 0 32 -2,-0.4 2,-0.3 36,-0.2 36,-0.1 -0.410 71.7 114.8 -77.1 64.8 18.4 8.8 -13.0 153 153 A H - 0 0 95 -2,-2.8 2,-0.5 34,-0.2 -2,-0.2 -0.996 58.1-147.2-142.5 144.1 20.1 6.0 -11.1 154 154 A E - 0 0 40 -2,-0.3 2,-0.1 10,-0.1 -82,-0.1 -0.948 19.0-153.9-114.3 121.6 21.7 5.4 -7.7 155 155 A a - 0 0 4 -2,-0.5 3,-0.5 -84,-0.1 2,-0.3 -0.403 23.0-104.1 -85.5 168.0 24.6 2.9 -7.5 156 156 A D S S+ 0 0 149 1,-0.2 -1,-0.1 -2,-0.1 0, 0.0 -0.666 98.1 31.8 -94.4 150.6 25.6 0.9 -4.5 157 157 A G S S+ 0 0 61 1,-0.3 -1,-0.2 -2,-0.3 3,-0.1 0.375 78.5 139.6 89.2 -4.6 28.7 1.9 -2.5 158 158 A T > - 0 0 5 -3,-0.5 3,-2.1 1,-0.1 -1,-0.3 -0.444 66.5 -96.3 -73.6 140.6 28.5 5.6 -3.2 159 159 A P G > S+ 0 0 56 0, 0.0 3,-1.0 0, 0.0 4,-0.4 -0.465 110.9 0.5 -60.4 124.4 29.4 7.8 -0.1 160 160 A D G 3 S- 0 0 152 1,-0.2 -2,-0.1 -2,-0.2 -33,-0.0 0.468 107.4-101.8 73.8 4.4 26.1 8.8 1.5 161 161 A N G < S+ 0 0 101 -3,-2.1 -1,-0.2 1,-0.1 3,-0.0 0.805 113.6 84.2 48.4 35.3 24.2 6.7 -1.2 162 162 A D < + 0 0 57 -3,-1.0 3,-0.2 -8,-0.0 -2,-0.1 0.288 65.4 79.8-143.8 7.0 23.4 10.1 -2.8 163 163 A T + 0 0 17 -4,-0.4 -37,-0.1 1,-0.2 -35,-0.1 -0.001 44.2 111.8-114.5 29.1 26.6 10.7 -4.9 164 164 A T S S- 0 0 0 1,-0.2 -38,-0.4 -38,-0.2 2,-0.3 0.926 101.2 -4.4 -63.7 -41.8 26.3 8.6 -8.1 165 165 A F S S- 0 0 17 -3,-0.2 -1,-0.2 -39,-0.2 25,-0.1 -0.919 80.3-123.7-143.9 157.5 26.0 11.9 -10.0 166 166 A E - 0 0 27 -36,-0.5 24,-0.2 -2,-0.3 23,-0.2 -0.384 43.5 -64.7 -96.4-175.5 25.7 15.5 -8.8 167 167 A S - 0 0 0 -2,-0.1 -35,-2.3 -41,-0.1 -34,-0.3 -0.057 26.4-140.1 -68.9 166.6 23.0 18.1 -9.4 168 168 A A S S+ 0 0 0 23,-2.3 -35,-0.3 22,-0.6 24,-0.2 0.834 93.2 1.1 -92.3 -45.8 22.0 19.8 -12.7 169 169 A V S S- 0 0 2 22,-2.4 2,-0.2 -37,-0.1 -35,-0.2 -0.515 72.8-178.4-145.5 69.9 21.4 23.4 -11.4 170 170 A D E -p 134 0F 14 -37,-1.6 -35,-2.1 22,-0.2 2,-0.4 -0.563 8.3-167.6 -73.5 134.9 22.2 23.8 -7.7 171 171 A I E +pq 135 194F 0 22,-1.1 24,-2.7 -2,-0.2 2,-0.3 -0.997 18.9 144.4-126.7 128.0 21.5 27.3 -6.5 172 172 A K E +p 136 0F 62 -37,-2.8 -35,-2.0 -2,-0.4 -34,-0.5 -0.910 34.7 29.2-151.1 178.5 22.6 28.6 -3.2 173 173 A G S S- 0 0 10 -2,-0.3 2,-1.4 -37,-0.3 -2,-0.0 -0.260 116.5 -18.7 66.9-150.8 23.9 31.5 -1.2 174 174 A A S S+ 0 0 44 1,-0.1 2,-1.3 29,-0.0 -1,-0.2 -0.361 79.2 140.2 -87.7 54.7 23.0 35.1 -2.2 175 175 A S + 0 0 0 -2,-1.4 29,-0.3 -38,-0.2 -1,-0.1 -0.489 30.0 176.1 -93.7 60.8 22.0 34.2 -5.8 176 176 A N + 0 0 90 -2,-1.3 28,-1.8 27,-0.2 2,-0.4 0.619 61.1 22.5 -41.5 -33.6 19.2 36.7 -5.2 177 177 A T E S+ g 0 204B 31 26,-0.2 -37,-1.5 -3,-0.2 -36,-1.2 -0.967 72.2 157.6-145.1 122.7 17.8 36.6 -8.7 178 178 A V E -fg 141 205B 0 26,-1.4 28,-2.3 -2,-0.4 -171,-0.5 -0.991 23.4-155.8-145.4 144.8 18.2 33.7 -11.1 179 179 A T E -fg 142 206B 0 -38,-2.0 -36,-2.4 -2,-0.3 2,-0.6 -0.994 4.6-170.6-125.2 120.5 16.2 32.4 -14.1 180 180 A V E +fg 143 207B 0 26,-3.3 28,-2.1 -2,-0.4 2,-0.3 -0.970 28.6 162.5-109.7 111.5 16.5 28.8 -15.1 181 181 A S E +fg 144 208B 0 -38,-2.3 -36,-2.1 -2,-0.6 -35,-0.3 -0.975 43.1 1.6-140.8 154.4 14.8 28.5 -18.5 182 182 A Y S S+ 0 0 8 26,-1.8 157,-3.5 -2,-0.3 2,-0.4 0.736 78.8 150.6 47.5 36.3 14.3 26.3 -21.6 183 183 A N - 0 0 0 155,-0.3 28,-2.7 25,-0.2 2,-0.9 -0.777 45.1-140.7 -99.0 136.6 16.6 23.6 -20.3 184 184 A Y E +xy 147 211G 55 -38,-2.7 -36,-2.2 -2,-0.4 2,-0.6 -0.867 28.9 178.0 -96.6 106.8 16.2 20.0 -21.3 185 185 A I E +xy 148 212G 0 26,-2.5 28,-2.6 -2,-0.9 2,-0.3 -0.946 10.0 152.8-116.5 112.9 16.9 18.1 -18.1 186 186 A H E +xy 149 213G 36 -38,-1.2 -36,-1.1 -2,-0.6 28,-0.2 -0.987 51.4 22.9-143.1 150.3 16.6 14.3 -18.1 187 187 A G E S+ 0 0 3 26,-1.4 -37,-0.7 27,-0.9 2,-0.4 0.989 82.3 136.7 60.3 59.9 18.0 11.3 -16.4 188 188 A V E - y 0 215G 2 26,-1.0 28,-1.8 1,-0.2 29,-0.3 -0.956 41.2-165.3-144.1 119.0 19.0 13.3 -13.2 189 189 A K E S+ 0 0 45 -38,-0.5 28,-2.7 -2,-0.4 2,-0.9 0.998 87.6 28.1 -65.9 -68.1 18.4 12.1 -9.7 190 190 A K E S+ y 0 217G 18 1,-0.2 -22,-0.6 -24,-0.2 -1,-0.3 -0.830 71.7 180.0 -99.7 102.2 19.0 15.4 -7.8 191 191 A V - 0 0 3 26,-2.3 -22,-2.4 -2,-0.9 -23,-2.3 0.987 53.4 -32.6 -69.0 -60.0 18.0 18.2 -10.2 192 192 A G - 0 0 2 26,-1.2 29,-1.7 25,-0.2 -22,-0.2 -0.942 43.1-139.9-170.5 143.8 18.6 21.4 -8.1 193 193 A L E - r 0 221F 19 -2,-0.3 -22,-1.1 27,-0.2 2,-0.2 -0.471 3.5-158.9 -94.0 169.2 18.6 23.0 -4.8 194 194 A D E S+qr 171 222F 0 27,-1.2 29,-1.1 1,-0.6 -22,-0.2 -0.750 86.7 11.2-146.2 79.2 17.5 26.5 -3.8 195 195 A G S S- 0 0 0 -24,-2.7 -1,-0.6 -2,-0.2 -23,-0.1 0.247 72.5-130.6 111.1 123.7 19.5 26.8 -0.6 196 196 A S S S+ 0 0 55 -3,-0.1 2,-0.3 -26,-0.1 -24,-0.1 0.704 86.5 4.7 -76.5 -20.6 22.2 24.4 0.5 197 197 A S S > S- 0 0 44 3,-0.2 3,-0.5 26,-0.1 -1,-0.1 -0.918 88.1 -84.3-152.8 176.9 20.7 24.0 4.0 198 198 A S T 3 S+ 0 0 53 -2,-0.3 3,-0.1 1,-0.2 71,-0.0 0.759 126.8 47.2 -58.1 -29.9 17.7 24.9 6.2 199 199 A S T 3 S+ 0 0 103 1,-0.2 2,-2.2 2,-0.0 -1,-0.2 0.714 90.4 83.5 -86.1 -23.1 19.4 28.2 7.1 200 200 A D < + 0 0 32 -3,-0.5 2,-0.3 2,-0.0 -1,-0.2 -0.458 66.6 151.1 -81.6 70.4 20.3 29.1 3.5 201 201 A T + 0 0 66 -2,-2.2 2,-0.3 -6,-0.1 23,-0.3 -0.708 24.7 51.8-104.1 150.5 16.8 30.6 2.8 202 202 A G + 0 0 22 21,-1.4 21,-0.2 -2,-0.3 24,-0.1 -0.939 40.8 122.8 134.1-153.3 15.9 33.4 0.4 203 203 A R - 0 0 13 -2,-0.3 23,-1.9 22,-0.2 2,-0.5 0.385 52.8-116.7 66.2 153.1 16.5 34.2 -3.3 204 204 A N E +gh 177 226B 53 -28,-1.8 -26,-1.4 -29,-0.3 2,-0.4 -0.974 41.2 177.9-124.2 108.8 13.9 34.9 -6.0 205 205 A I E -gh 178 227B 0 21,-2.5 23,-2.1 -2,-0.5 2,-0.4 -0.949 18.2-157.5-124.4 141.2 14.1 32.3 -8.7 206 206 A T E -gh 179 228B 0 -28,-2.3 -26,-3.3 -2,-0.4 2,-0.5 -0.950 3.9-171.2-116.4 131.6 12.2 31.6 -11.9 207 207 A Y E +gh 180 229B 5 21,-2.6 23,-1.8 -2,-0.4 2,-0.4 -0.975 23.0 165.3-121.1 110.9 12.0 28.3 -13.6 208 208 A H E -gh 181 230B 7 -28,-2.1 -26,-1.8 -2,-0.5 -25,-0.2 -0.987 53.3 -2.7-138.1 143.7 10.3 28.6 -17.0 209 209 A H S S+ 0 0 5 21,-1.7 2,-0.3 -2,-0.4 23,-0.2 0.778 83.1 152.0 55.3 33.0 9.8 26.5 -20.1 210 210 A N - 0 0 0 20,-0.3 23,-2.6 -28,-0.2 2,-0.7 -0.725 40.3-142.7 -92.2 143.9 12.1 23.8 -18.7 211 211 A Y E -yz 184 233G 42 -28,-2.7 -26,-2.5 -2,-0.3 2,-0.6 -0.891 18.1-173.6-112.0 100.0 11.6 20.2 -19.9 212 212 A Y E +yz 185 234G 2 21,-2.6 23,-2.8 -2,-0.7 2,-0.4 -0.861 10.2 170.6 -95.8 122.0 12.1 17.8 -17.0 213 213 A N E -yz 186 235G 35 -28,-2.6 -26,-1.4 -2,-0.6 23,-0.2 -0.983 61.3 -5.5-137.7 127.0 12.0 14.1 -18.1 214 214 A D E S+ 0 0 66 21,-1.2 -26,-1.0 -2,-0.4 -27,-0.9 0.964 88.8 143.6 58.4 55.9 13.0 11.1 -16.0 215 215 A V E -yz 188 237G 0 21,-1.3 23,-2.0 20,-0.4 24,-0.4 -0.875 41.6-151.3-121.1 154.4 14.2 13.0 -13.0 216 216 A N E - 0 0 43 -28,-1.8 24,-2.4 -27,-0.4 23,-1.1 0.906 59.8 -14.8 -94.5 -52.1 13.8 12.0 -9.4 217 217 A A E S+y 190 0G 12 -28,-2.7 -26,-2.3 -29,-0.3 -1,-0.3 -0.904 90.7 54.7-150.0 173.5 13.8 15.0 -7.1 218 218 A R + 0 0 55 23,-0.5 -26,-1.2 -2,-0.3 3,-0.5 0.937 34.1 170.7 64.0 68.3 14.4 18.8 -6.6 219 219 A L S S- 0 0 1 22,-1.7 23,-0.3 1,-0.8 2,-0.1 -0.128 102.2 -32.8-112.8 41.1 12.4 20.7 -9.3 220 220 A P - 0 0 2 0, 0.0 23,-2.5 0, 0.0 2,-1.0 0.512 67.3-141.8-104.7-174.7 13.6 22.6 -7.1 221 221 A L E -rs 193 243F 5 -29,-1.7 -27,-1.2 -3,-0.5 2,-0.4 -0.904 39.3-154.7 -96.3 96.9 14.1 21.8 -3.5 222 222 A Q E -rs 194 244F 2 21,-2.7 23,-2.5 -2,-1.0 2,-0.5 -0.675 20.3-174.3 -83.8 130.9 13.0 25.4 -2.4 223 223 A R E - s 0 245F 24 -29,-1.1 -21,-1.4 -2,-0.4 23,-0.2 -0.944 59.7 -47.1-127.4 101.9 14.2 26.8 0.9 224 224 A G S S+ 0 0 4 21,-2.0 24,-0.2 -2,-0.5 -1,-0.2 -0.033 99.9 69.5 68.7-170.3 12.6 30.2 1.6 225 225 A G S S- 0 0 24 22,-0.2 24,-2.6 23,-0.2 2,-0.4 -0.118 89.8 -52.6 64.8-157.6 12.3 33.0 -0.9 226 226 A L E -hi 204 249B 22 -23,-1.9 -21,-2.5 22,-0.2 2,-0.4 -0.958 41.3-170.8-123.6 138.9 10.1 33.0 -4.0 227 227 A V E -hi 205 250B 0 22,-2.3 24,-1.8 -2,-0.4 2,-0.6 -0.996 2.7-169.1-131.7 123.4 9.8 30.5 -6.8 228 228 A H E -hi 206 251B 0 -23,-2.1 -21,-2.6 -2,-0.4 2,-0.6 -0.968 8.8-177.1-113.3 111.5 7.9 31.2 -9.9 229 229 A A E +hi 207 252B 0 22,-2.4 24,-2.2 -2,-0.6 2,-0.3 -0.930 14.1 160.0-113.5 107.4 7.5 28.0 -12.0 230 230 A Y E +hi 208 253B 6 -23,-1.8 -21,-1.7 -2,-0.6 -20,-0.3 -0.964 54.4 3.5-133.9 148.1 5.7 28.5 -15.3 231 231 A N S S+ 0 0 0 22,-1.3 2,-0.3 -2,-0.3 24,-0.2 0.695 82.4 149.4 56.4 28.1 5.3 26.7 -18.6 232 232 A N - 0 0 0 21,-0.2 24,-2.6 -23,-0.2 2,-0.7 -0.652 43.4-140.9 -91.6 143.2 7.5 23.8 -17.5 233 233 A L E -za 211 256G 2 -23,-2.6 -21,-2.6 -2,-0.3 2,-0.8 -0.926 19.7-174.0-106.2 106.5 6.9 20.3 -18.8 234 234 A Y E +za 212 257G 0 22,-1.8 24,-1.9 -2,-0.7 2,-0.4 -0.824 13.2 164.0-104.9 93.7 7.3 17.8 -15.9 235 235 A T E +za 213 258G 14 -23,-2.8 -21,-1.2 -2,-0.8 -20,-0.4 -0.876 57.7 8.4-113.8 145.2 7.2 14.2 -17.2 236 236 A N E + 0 0 66 22,-1.8 -21,-1.3 -2,-0.4 2,-0.9 0.961 66.0 178.6 53.5 66.9 8.3 11.1 -15.4 237 237 A I E -za 215 260G 2 22,-1.4 24,-2.4 -3,-0.2 -21,-0.2 -0.867 6.2-172.8 -99.1 102.4 9.1 12.4 -11.9 238 238 A T S S+ 0 0 60 -23,-2.0 -22,-0.2 -2,-0.9 -1,-0.1 0.585 73.3 11.2 -75.4 -12.2 10.1 9.3 -10.0 239 239 A G S S- 0 0 17 -23,-1.1 2,-0.3 -24,-0.4 -22,-0.2 0.652 119.9 -36.4-127.1 -69.2 10.4 10.8 -6.5 240 240 A S - 0 0 1 -24,-2.4 -1,-0.4 1,-0.1 22,-0.2 -0.950 43.7-153.2-157.7 159.7 9.0 14.3 -5.9 241 241 A G S S+ 0 0 0 21,-2.3 -22,-1.7 1,-0.4 2,-0.5 0.415 72.8 12.4-106.1-112.1 8.8 17.5 -7.9 242 242 A L E - t 0 264F 2 21,-2.3 23,-2.7 -23,-0.3 2,-0.7 -0.579 64.9-167.1 -73.5 118.4 8.7 21.0 -6.4 243 243 A N E -st 221 265F 2 -23,-2.5 -21,-2.7 -2,-0.5 2,-1.0 -0.922 4.7-161.8-110.0 100.6 9.5 20.7 -2.7 244 244 A V E +s 222 0F 1 21,-2.6 30,-2.2 -2,-0.7 3,-0.2 -0.746 26.5 157.8 -91.0 101.9 8.5 24.0 -1.1 245 245 A R E > +s 223 0F 13 -23,-2.5 -21,-2.0 -2,-1.0 3,-1.5 -0.551 39.3 36.9-119.9 178.9 10.3 24.2 2.2 246 246 A Q T 3 S- 0 0 32 25,-0.4 27,-0.2 1,-0.3 -1,-0.2 0.845 127.1 -59.6 43.1 48.7 11.5 26.6 4.9 247 247 A N T 3 S+ 0 0 100 25,-2.2 -1,-0.3 -3,-0.2 2,-0.2 0.782 90.6 159.5 54.5 35.8 8.5 28.9 4.4 248 248 A G < - 0 0 0 -3,-1.5 27,-2.1 24,-0.3 2,-0.5 -0.537 33.8-134.9 -82.6 153.7 9.2 29.5 0.7 249 249 A Q E -ij 226 275B 61 -24,-2.6 -22,-2.3 25,-0.2 2,-0.3 -0.950 21.3-170.6-113.4 131.2 6.4 30.7 -1.5 250 250 A A E -ij 227 276B 1 25,-2.1 27,-0.8 -2,-0.5 2,-0.4 -0.830 18.1-157.7-120.7 156.1 5.8 29.3 -4.9 251 251 A L E -ij 228 277B 8 -24,-1.8 -22,-2.4 -2,-0.3 2,-0.7 -0.948 15.8-170.3-130.7 104.4 3.5 30.2 -7.8 252 252 A I E +ij 229 278B 0 25,-2.7 27,-2.3 -2,-0.4 2,-0.4 -0.871 19.5 162.7-103.2 106.5 3.0 27.1 -10.0 253 253 A E E -ij 230 279B 11 -24,-2.2 -22,-1.3 -2,-0.7 27,-0.2 -0.972 49.9 -5.3-138.7 141.5 1.3 28.1 -13.2 254 254 A N S S+ 0 0 28 25,-1.3 2,-0.2 -2,-0.4 27,-0.2 0.860 84.9 144.1 55.6 41.6 0.6 26.8 -16.7 255 255 A N - 0 0 0 -24,-0.2 27,-1.7 -25,-0.1 2,-0.5 -0.658 47.4-135.2-105.1 159.8 2.8 23.7 -16.2 256 256 A W E -a 233 0G 12 -24,-2.6 -22,-1.8 -2,-0.2 2,-0.3 -0.861 23.9-177.5-121.4 98.6 2.2 20.2 -17.6 257 257 A F E +a 234 0G 0 -2,-0.5 2,-0.3 -24,-0.2 -22,-0.2 -0.701 9.8 162.0 -91.6 146.4 2.7 17.4 -15.0 258 258 A E E +a 235 0G 38 -24,-1.9 -22,-1.8 -2,-0.3 35,-0.2 -0.838 60.2 6.7-169.2 127.4 2.4 13.8 -16.1 259 259 A K E S+ 0 0 108 33,-2.6 -22,-1.4 -2,-0.3 2,-0.4 0.969 91.1 147.5 62.3 54.9 3.5 10.5 -14.6 260 260 A A E -ab 237 294G 1 33,-0.6 35,-2.4 32,-0.4 2,-0.5 -0.975 43.6-149.6-128.1 136.3 4.8 12.2 -11.5 261 261 A I E S- b 0 295G 53 -24,-2.4 35,-0.2 -2,-0.4 -22,-0.1 -0.906 85.9 -8.2-102.7 130.6 5.0 11.2 -7.9 262 262 A N S S+ 0 0 3 33,-2.6 -21,-2.3 -2,-0.5 -1,-0.2 0.845 75.3 174.1 51.9 45.8 4.6 14.0 -5.3 263 263 A P S S+ 0 0 0 0, 0.0 -21,-2.3 0, 0.0 2,-0.4 0.788 73.0 25.9 -52.1 -34.5 4.8 16.7 -8.0 264 264 A V E S+t 242 0F 0 -23,-0.2 42,-2.1 -21,-0.1 2,-0.3 -0.959 89.5 129.9-135.0 115.2 4.0 19.5 -5.5 265 265 A T E -tU 243 305F 0 -23,-2.7 -21,-2.6 -2,-0.4 2,-0.3 -0.898 48.1-139.4-155.2 173.8 5.0 18.8 -1.9 266 266 A S E + U 0 304F 3 38,-1.5 38,-1.9 -2,-0.3 2,-0.3 -0.834 48.5 136.9-145.2 99.7 6.8 20.0 1.3 267 267 A R + 0 0 5 -2,-0.3 36,-0.1 36,-0.2 -2,-0.1 -0.950 30.6 55.7-145.9 166.8 8.7 17.2 3.0 268 268 A Y S S+ 0 0 93 -2,-0.3 35,-0.1 34,-0.3 -1,-0.1 0.283 100.7 58.9 93.2 -5.0 11.9 16.1 4.7 269 269 A D S S- 0 0 23 33,-0.4 34,-0.1 2,-0.1 3,-0.1 0.678 85.8-141.1-114.7 -42.1 12.1 18.7 7.5 270 270 A G S S+ 0 0 19 32,-0.6 2,-0.3 1,-0.2 33,-0.1 0.503 74.1 45.8 89.4 9.9 8.8 18.1 9.3 271 271 A K S S+ 0 0 120 31,-0.1 -25,-0.4 1,-0.1 -1,-0.2 -0.975 81.6 49.7-168.2 170.3 8.2 21.8 9.9 272 272 A N S S- 0 0 65 -2,-0.3 -25,-2.2 1,-0.1 -24,-0.3 0.914 71.0-161.1 54.2 51.3 8.1 25.3 8.3 273 273 A F - 0 0 70 -27,-0.2 -28,-0.2 -28,-0.1 -1,-0.1 -0.304 7.6-132.3 -65.2 140.4 6.1 24.2 5.3 274 274 A G - 0 0 5 -30,-2.2 2,-0.3 -27,-0.2 -25,-0.2 -0.316 19.2-125.7 -83.1 176.4 6.1 26.4 2.3 275 275 A T E -j 249 0B 34 -27,-2.1 -25,-2.1 -30,-0.1 2,-0.3 -0.836 16.4-157.5-123.1 158.5 3.0 27.4 0.4 276 276 A W E -j 250 0B 0 -2,-0.3 36,-1.9 -27,-0.2 37,-1.2 -0.975 11.8-152.4-138.3 151.0 2.0 27.2 -3.2 277 277 A V E -j 251 0B 26 -27,-0.8 -25,-2.7 -2,-0.3 2,-0.5 -0.999 21.5-158.3-119.7 116.7 -0.5 29.0 -5.5 278 278 A L E +j 252 0B 22 -2,-0.5 2,-0.3 -27,-0.2 -25,-0.2 -0.910 22.2 155.6-104.6 120.2 -1.7 26.7 -8.3 279 279 A K E -j 253 0B 107 -27,-2.3 -25,-1.3 -2,-0.5 -24,-0.1 -0.955 57.2 -3.7-150.9 127.4 -3.1 28.2 -11.5 280 280 A G S S+ 0 0 46 -2,-0.3 47,-0.5 -27,-0.2 -27,-0.1 0.652 80.5 142.2 75.7 18.1 -3.6 27.1 -15.1 281 281 A N - 0 0 8 2,-0.4 -25,-0.2 -27,-0.2 -1,-0.2 -0.276 67.9-106.7 -82.4 172.4 -1.8 23.8 -14.9 282 282 A N S S+ 0 0 11 -27,-1.7 2,-0.5 45,-0.1 -26,-0.1 0.729 112.8 63.8 -71.2 -21.9 -3.0 20.6 -16.8 283 283 A I + 0 0 1 -28,-0.3 -2,-0.4 1,-0.1 -28,-0.1 -0.912 57.1 161.4-102.0 126.4 -4.1 19.3 -13.4 284 284 A T + 0 0 87 -2,-0.5 -1,-0.1 1,-0.4 -2,-0.1 0.641 67.0 6.0-114.6 -29.6 -6.9 21.5 -12.0 285 285 A K S > S- 0 0 109 25,-0.0 3,-2.4 0, 0.0 -1,-0.4 -0.937 87.1 -89.2-150.0 164.5 -8.4 19.2 -9.4 286 286 A P T > S+ 0 0 59 0, 0.0 3,-1.8 0, 0.0 4,-0.4 0.709 115.4 75.5 -50.1 -23.9 -7.7 15.7 -7.9 287 287 A A T >> S+ 0 0 54 1,-0.3 4,-0.6 2,-0.2 3,-0.6 0.773 89.9 56.7 -61.5 -27.1 -9.8 14.2 -10.7 288 288 A D H <> S+ 0 0 24 -3,-2.4 4,-2.2 1,-0.2 -1,-0.3 0.409 83.5 85.6 -85.3 -0.2 -7.0 14.8 -13.1 289 289 A F H <4>S+ 0 0 24 -3,-1.8 5,-2.8 2,-0.2 -1,-0.2 0.864 95.0 41.1 -67.8 -37.2 -4.6 12.8 -11.0 290 290 A S H X45S+ 0 0 102 -3,-0.6 3,-0.8 -4,-0.4 -1,-0.2 0.878 114.4 53.6 -75.4 -39.5 -5.7 9.5 -12.7 291 291 A T H 3<5S+ 0 0 88 -4,-0.6 -2,-0.2 1,-0.2 -1,-0.2 0.847 119.6 31.7 -62.6 -40.4 -5.8 11.2 -16.1 292 292 A Y T 3<5S- 0 0 45 -4,-2.2 -33,-2.6 2,-0.1 -32,-0.4 0.151 111.2-113.2-108.8 20.1 -2.2 12.5 -15.9 293 293 A S T < 5 + 0 0 57 -3,-0.8 -33,-0.6 -35,-0.2 2,-0.5 0.843 55.1 166.4 51.0 41.3 -0.8 9.6 -13.8 294 294 A I E < -b 260 0G 8 -5,-2.8 2,-0.3 -6,-0.2 -1,-0.2 -0.780 10.1-178.8 -89.2 125.3 -0.2 11.8 -10.8 295 295 A T E -b 261 0G 75 -35,-2.4 -33,-2.6 -2,-0.5 2,-0.3 -0.881 12.8-152.3-125.5 154.9 0.5 9.8 -7.7 296 296 A W - 0 0 49 -2,-0.3 2,-0.2 -35,-0.2 -56,-0.1 -0.973 9.2-175.2-131.7 144.3 1.3 10.7 -4.0 297 297 A T - 0 0 66 -2,-0.3 2,-0.1 1,-0.1 -35,-0.0 -0.735 20.9-120.3-127.8 174.9 3.2 9.1 -1.2 298 298 A A - 0 0 59 -2,-0.2 2,-0.3 7,-0.0 -1,-0.1 -0.274 20.7-136.7-102.2-170.3 3.8 9.8 2.4 299 299 A D - 0 0 43 -2,-0.1 4,-0.1 2,-0.1 0, 0.0 -0.984 22.8-117.5-151.3 156.5 6.9 10.4 4.4 300 300 A T S S+ 0 0 142 -2,-0.3 -1,-0.0 2,-0.1 3,-0.0 0.686 102.4 52.3 -65.5 -23.0 8.4 9.4 7.7 301 301 A K S S- 0 0 102 1,-0.1 -31,-0.2 -30,-0.0 -33,-0.2 -0.835 110.0 -77.2-113.7 155.7 8.4 13.1 8.8 302 302 A P + 0 0 81 0, 0.0 -32,-0.6 0, 0.0 -33,-0.4 -0.186 64.9 160.9 -51.5 137.3 5.5 15.6 8.8 303 303 A Y - 0 0 82 -36,-0.1 2,-0.4 -33,-0.1 -36,-0.2 -0.897 33.5-132.4-150.5 173.7 4.9 16.8 5.3 304 304 A V E -U 266 0F 55 -38,-1.9 -38,-1.5 -2,-0.3 2,-0.3 -0.993 17.7-164.0-140.1 128.7 2.2 18.4 3.1 305 305 A N E -U 265 0F 13 -2,-0.4 3,-0.5 -40,-0.2 2,-0.3 -0.813 28.8-126.9-110.7 154.5 1.1 17.2 -0.4 306 306 A A + 0 0 4 -42,-2.1 3,-0.3 -2,-0.3 -41,-0.1 -0.216 67.4 129.7 -89.5 41.8 -0.9 19.1 -3.0 307 307 A D S S+ 0 0 74 -2,-0.3 -1,-0.2 1,-0.2 -18,-0.1 0.759 72.6 49.9 -68.1 -23.5 -3.2 16.1 -3.1 308 308 A S S S- 0 0 71 -3,-0.5 -1,-0.2 2,-0.1 -2,-0.1 0.697 103.8-140.7 -83.3 -19.9 -6.2 18.4 -2.7 309 309 A W + 0 0 14 -3,-0.3 2,-0.3 1,-0.2 -2,-0.1 0.949 56.6 125.5 53.2 56.4 -4.7 20.5 -5.5 310 310 A T S S- 0 0 84 -25,-0.1 -1,-0.2 -34,-0.0 2,-0.2 -0.941 70.2 -90.1-134.8 153.9 -5.6 23.8 -3.9 311 311 A S - 0 0 57 -2,-0.3 -34,-0.2 -33,-0.2 3,-0.0 -0.458 28.5-165.9 -69.4 134.9 -3.4 26.8 -3.1 312 312 A T - 0 0 61 -36,-1.9 2,-0.2 -2,-0.2 -35,-0.2 0.338 69.7 -10.0-102.2 3.3 -1.9 26.6 0.4 313 313 A G S S- 0 0 28 -37,-1.2 2,-0.2 -63,-0.1 -64,-0.0 -0.843 77.2 -85.3-167.0-154.5 -0.8 30.2 0.5 314 314 A T - 0 0 102 -2,-0.2 -64,-0.1 -37,-0.1 -39,-0.1 -0.648 23.7-140.4-127.1 179.8 -0.3 33.4 -1.6 315 315 A F - 0 0 32 -2,-0.2 3,-0.1 -66,-0.1 -89,-0.0 -0.986 23.7-111.4-148.0 135.4 2.3 34.9 -3.9 316 316 A P - 0 0 59 0, 0.0 2,-0.1 0, 0.0 3,-0.1 -0.170 54.1 -77.8 -60.1 162.7 3.6 38.5 -4.3 317 317 A T - 0 0 138 1,-0.1 2,-0.2 2,-0.0 0, 0.0 -0.442 56.0-105.6 -64.2 132.5 2.8 40.3 -7.6 318 318 A V - 0 0 34 1,-0.1 -1,-0.1 -2,-0.1 4,-0.1 -0.462 31.2-158.5 -63.2 125.9 5.2 39.1 -10.3 319 319 A A + 0 0 87 -2,-0.2 -1,-0.1 2,-0.1 -312,-0.0 0.996 66.5 51.7 -69.2 -73.6 7.8 41.8 -10.9 320 320 A Y S S- 0 0 36 1,-0.1 2,-0.3 -315,-0.0 -313,-0.1 0.068 91.7 -99.7 -57.1 175.8 9.2 41.1 -14.4 321 321 A N + 0 0 130 -315,-0.1 2,-0.3 2,-0.0 -316,-0.2 -0.785 46.3 157.7-105.6 146.5 7.0 40.6 -17.5 322 322 A Y - 0 0 47 -2,-0.3 -4,-0.0 -4,-0.1 -316,-0.0 -0.957 28.9-151.5-162.0 147.7 6.1 37.3 -18.9 323 323 A S - 0 0 94 -2,-0.3 2,-0.2 -318,-0.0 26,-0.1 -0.918 23.2-154.8-129.6 100.5 3.3 35.9 -21.1 324 324 A P - 0 0 43 0, 0.0 2,-0.2 0, 0.0 3,-0.1 -0.550 4.5-139.8 -79.9 142.5 2.7 32.2 -20.4 325 325 A V - 0 0 6 -2,-0.2 -94,-0.2 1,-0.2 5,-0.1 -0.463 40.0 -77.6 -90.6 167.0 1.2 29.8 -23.0 326 326 A S > - 0 0 64 -2,-0.2 4,-1.7 1,-0.1 3,-0.3 -0.238 37.6-114.3 -63.9 157.0 -1.4 27.2 -22.0 327 327 A A H > S+ 0 0 8 -47,-0.5 4,-2.2 1,-0.2 5,-0.1 0.890 118.6 56.0 -58.3 -39.9 -0.4 23.9 -20.2 328 328 A Q H > S+ 0 0 93 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.857 104.9 52.6 -61.8 -36.9 -1.5 22.0 -23.3 329 329 A b H >>S+ 0 0 2 -3,-0.3 4,-3.3 2,-0.2 5,-0.8 0.869 106.2 51.2 -69.4 -36.5 0.9 24.1 -25.5 330 330 A V H X5S+ 0 0 0 -4,-1.7 4,-0.7 1,-0.2 -2,-0.2 0.956 111.0 51.0 -64.6 -40.0 3.9 23.4 -23.3 331 331 A K H <5S+ 0 0 66 -4,-2.2 -2,-0.2 -5,-0.2 -1,-0.2 0.868 121.4 33.1 -60.4 -39.8 3.0 19.8 -23.7 332 332 A D H <5S+ 0 0 80 -4,-1.8 -2,-0.2 -5,-0.1 -3,-0.2 0.947 133.2 21.3 -80.6 -60.3 2.8 20.2 -27.5 333 333 A K H ><5S+ 0 0 84 -4,-3.3 3,-2.5 1,-0.1 -3,-0.2 0.867 100.6 79.2 -83.5 -41.1 5.4 22.7 -28.4 334 334 A L G >X S- 0 0 0 -157,-3.5 3,-0.5 -193,-0.2 5,-0.3 -0.417 95.1 -37.3 99.3-173.3 17.5 22.5 -25.0 340 340 A V T 3 S+ 0 0 27 1,-0.2 -194,-0.1 -2,-0.1 -195,-0.1 -0.482 112.3 36.1 -89.6 160.4 20.5 23.1 -27.2 341 341 A G T 3 S+ 0 0 38 -2,-0.2 -1,-0.2 -196,-0.2 -2,-0.0 0.559 83.0 106.0 75.4 4.0 20.4 23.4 -31.0 342 342 A K S X S- 0 0 62 -3,-0.5 3,-1.8 -197,-0.2 -1,-0.1 0.244 93.3-119.4 -94.9 9.7 17.0 25.3 -30.8 343 343 A N T 3 - 0 0 124 1,-0.3 -3,-0.1 -198,-0.1 -198,-0.0 0.837 64.9 -67.0 51.9 35.1 18.9 28.5 -31.6 344 344 A L T 3 S+ 0 0 54 -5,-0.3 -1,-0.3 1,-0.2 2,-0.1 0.764 83.8 179.8 57.1 35.5 17.7 29.7 -28.3 345 345 A A < - 0 0 35 -3,-1.8 2,-0.3 -9,-0.1 -1,-0.2 -0.377 14.8-144.0 -70.7 138.4 14.1 29.8 -29.6 346 346 A T - 0 0 83 -2,-0.1 2,-0.7 -8,-0.0 -1,-0.1 -0.744 14.7-114.4-106.3 149.1 11.3 30.9 -27.2 347 347 A L + 0 0 8 -2,-0.3 2,-0.3 3,-0.0 -22,-0.1 -0.744 38.7 173.3 -87.7 115.5 7.7 29.6 -26.9 348 348 A T > - 0 0 62 -2,-0.7 3,-1.2 -24,-0.1 4,-0.1 -0.751 46.2-110.9-115.3 158.0 5.1 32.2 -27.8 349 349 A S G > S+ 0 0 92 -2,-0.3 3,-1.3 1,-0.3 -23,-0.1 0.734 115.5 69.4 -61.2 -24.4 1.3 31.8 -28.1 350 350 A T G 3 S+ 0 0 131 1,-0.3 -1,-0.3 2,-0.2 -3,-0.0 0.847 96.8 52.6 -61.2 -35.0 1.7 32.3 -31.9 351 351 A A G < 0 0 29 -3,-1.2 -1,-0.3 1,-0.2 -2,-0.2 0.405 360.0 360.0 -83.6 1.2 3.5 28.9 -31.9 352 352 A b < 0 0 75 -3,-1.3 -2,-0.2 -4,-0.1 -1,-0.2 0.931 360.0 360.0 -91.6 360.0 0.5 27.2 -30.2