==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 20-DEC-06 2OBV . COMPND 2 MOLECULE: S-ADENOSYLMETHIONINE SYNTHETASE ISOFORM TYPE-1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR E.S.PILKA,N.SHAFQAT,K.L.KAVANAGH,C.COOPER,V.HOZJAN,A.TURNBUL . 385 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15937.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 247 64.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 15 3.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 59 15.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 4.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 45 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 92 23.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 2.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 2 0 0 1 1 1 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 0 0 1 0 0 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 -3 A F > 0 0 196 0, 0.0 3,-1.3 0, 0.0 4,-0.4 0.000 360.0 360.0 360.0 141.7 -5.4 14.6 -0.7 2 -2 A Q G > + 0 0 202 1,-0.2 3,-1.5 2,-0.2 4,-0.0 0.857 360.0 64.6 -51.0 -38.8 -6.7 11.1 0.1 3 -1 A S G 3 S+ 0 0 89 1,-0.3 -1,-0.2 2,-0.1 178,-0.2 0.775 89.1 67.2 -59.5 -28.0 -3.2 10.0 1.0 4 0 A M G < S- 0 0 54 -3,-1.3 175,-1.9 174,-0.1 -1,-0.3 0.709 77.6-169.8 -71.4 -20.2 -3.1 12.5 3.9 5 16 A G < - 0 0 32 -3,-1.5 -3,-0.1 -4,-0.4 172,-0.1 0.788 19.1-140.7 32.8 66.2 -5.7 10.6 5.9 6 17 A V + 0 0 88 172,-0.1 2,-0.3 170,-0.1 172,-0.2 -0.282 31.8 166.7 -60.0 133.9 -6.3 13.3 8.5 7 18 A F E -A 177 0A 54 170,-2.0 170,-3.5 -3,-0.1 2,-0.3 -0.975 32.5-123.0-148.3 157.8 -6.8 11.9 12.1 8 19 A M E -A 176 0A 114 -2,-0.3 2,-0.3 168,-0.2 168,-0.2 -0.772 24.4-176.7 -95.5 148.1 -6.9 12.9 15.7 9 20 A F E -A 175 0A 59 166,-1.8 166,-2.6 -2,-0.3 2,-0.4 -0.969 8.1-155.8-148.1 135.2 -4.7 11.4 18.4 10 21 A T E +A 174 0A 59 -2,-0.3 2,-0.3 164,-0.2 164,-0.2 -0.896 14.4 170.0-114.6 136.2 -4.7 12.1 22.1 11 22 A S E -A 173 0A 5 162,-2.1 162,-3.0 -2,-0.4 2,-0.3 -0.948 12.9-157.5-132.6 156.9 -2.0 11.7 24.8 12 23 A E E -A 172 0A 66 -2,-0.3 2,-0.3 160,-0.3 160,-0.2 -0.847 6.7-172.8-124.9 168.0 -1.8 12.9 28.5 13 24 A S E -A 171 0A 0 158,-2.0 158,-2.6 -2,-0.3 2,-0.3 -0.936 11.4-145.2-148.5 168.1 0.9 13.6 31.1 14 25 A V E -A 170 0A 0 -2,-0.3 352,-0.4 156,-0.2 156,-0.3 -0.913 17.6-111.6-135.6 163.2 0.8 14.5 34.8 15 26 A G > - 0 0 1 154,-2.5 3,-1.4 -2,-0.3 6,-0.2 -0.328 38.1 -91.3 -92.2 178.3 2.8 16.6 37.1 16 27 A E T 3 S+ 0 0 12 1,-0.3 152,-0.2 134,-0.2 9,-0.1 0.730 122.3 50.1 -59.8 -26.4 5.2 15.9 40.0 17 28 A G T 3 S+ 0 0 0 150,-2.0 151,-0.4 62,-0.1 -1,-0.3 0.442 74.0 117.8 -97.9 -4.6 2.5 16.0 42.6 18 29 A H S <> S- 0 0 0 -3,-1.4 4,-2.5 149,-0.4 3,-0.2 -0.530 74.3-125.3 -56.4 130.4 0.0 13.7 40.9 19 30 A P H > S+ 0 0 0 0, 0.0 4,-1.6 0, 0.0 230,-0.2 0.806 108.0 50.8 -61.4 -36.2 -0.1 10.8 43.5 20 31 A D H > S+ 0 0 7 229,-0.2 4,-1.7 2,-0.2 232,-0.2 0.934 114.6 45.7 -59.6 -46.0 0.8 8.0 41.0 21 32 A K H > S+ 0 0 0 2,-0.2 4,-2.5 1,-0.2 5,-0.2 0.840 104.9 59.6 -68.6 -35.1 3.8 10.1 40.0 22 33 A I H X S+ 0 0 2 -4,-2.5 4,-2.4 1,-0.2 -1,-0.2 0.936 107.7 49.4 -52.8 -43.9 4.7 10.9 43.6 23 34 A C H X S+ 0 0 0 -4,-1.6 4,-2.9 2,-0.2 -2,-0.2 0.892 109.0 49.3 -65.6 -43.9 5.0 7.1 44.0 24 35 A D H X S+ 0 0 0 -4,-1.7 4,-2.3 226,-0.2 -1,-0.2 0.917 113.1 48.3 -60.8 -43.8 7.2 6.7 41.0 25 36 A Q H X S+ 0 0 5 -4,-2.5 4,-2.0 339,-0.3 -2,-0.2 0.897 113.5 46.3 -64.9 -41.6 9.5 9.5 42.1 26 37 A I H X S+ 0 0 0 -4,-2.4 4,-2.3 2,-0.2 5,-0.2 0.932 111.5 51.4 -66.3 -45.7 9.8 8.0 45.6 27 38 A S H X S+ 0 0 0 -4,-2.9 4,-1.9 1,-0.2 -2,-0.2 0.910 115.1 43.7 -57.0 -43.3 10.4 4.5 44.3 28 39 A D H X S+ 0 0 0 -4,-2.3 4,-2.5 2,-0.2 333,-0.5 0.779 108.7 55.9 -74.0 -29.0 13.2 5.8 42.1 29 40 A A H X S+ 0 0 6 -4,-2.0 4,-2.0 2,-0.2 -2,-0.2 0.876 109.1 48.7 -65.3 -38.7 14.6 8.0 44.9 30 41 A V H X S+ 0 0 0 -4,-2.3 4,-2.0 2,-0.2 -2,-0.2 0.923 111.4 50.1 -65.8 -43.7 14.9 4.8 47.0 31 42 A L H X S+ 0 0 0 -4,-1.9 4,-2.6 1,-0.2 -2,-0.2 0.937 111.5 47.7 -56.7 -51.6 16.6 3.1 44.0 32 43 A D H X S+ 0 0 12 -4,-2.5 4,-1.8 1,-0.2 -1,-0.2 0.871 108.0 55.2 -57.5 -43.5 19.1 6.0 43.6 33 44 A A H X S+ 0 0 17 -4,-2.0 4,-0.6 2,-0.2 -1,-0.2 0.900 111.3 45.3 -59.3 -41.8 19.8 6.0 47.3 34 45 A H H >X S+ 0 0 5 -4,-2.0 4,-3.1 1,-0.2 3,-1.4 0.957 110.6 52.3 -65.9 -49.0 20.8 2.3 47.2 35 46 A L H 3< S+ 0 0 9 -4,-2.6 -2,-0.2 1,-0.3 -1,-0.2 0.779 99.3 63.9 -60.9 -31.2 22.9 2.6 44.0 36 47 A K H 3< S+ 0 0 155 -4,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.795 119.8 25.1 -61.4 -30.5 25.0 5.5 45.4 37 48 A Q H << S+ 0 0 102 -3,-1.4 -2,-0.2 -4,-0.6 -1,-0.2 0.751 137.4 25.8-100.6 -35.3 26.2 3.0 48.1 38 49 A D >< - 0 0 8 -4,-3.1 3,-2.0 -5,-0.1 -1,-0.2 -0.852 59.9-168.9-137.0 94.4 25.8 -0.4 46.3 39 50 A P T 3 S+ 0 0 62 0, 0.0 -4,-0.1 0, 0.0 -1,-0.1 0.694 90.8 52.8 -57.7 -21.5 25.9 -0.2 42.5 40 51 A N T 3 S+ 0 0 71 -6,-0.1 -5,-0.1 2,-0.1 235,-0.0 0.145 78.0 146.7-103.1 18.3 24.7 -3.9 42.4 41 52 A A < - 0 0 1 -3,-2.0 2,-0.6 -10,-0.1 21,-0.2 -0.263 45.4-138.9 -51.7 134.4 21.6 -3.4 44.6 42 53 A K E +D 61 0B 22 19,-2.5 19,-2.3 233,-0.1 2,-0.4 -0.916 33.2 177.9 -97.4 115.6 18.6 -5.5 43.8 43 54 A V E +D 60 0B 0 -2,-0.6 232,-1.4 17,-0.2 17,-0.2 -0.983 28.7 160.8-131.7 128.8 15.6 -3.2 44.1 44 55 A A E +DE 59 274B 15 15,-1.7 15,-1.8 -2,-0.4 2,-0.7 -0.638 25.4 172.0-141.0 76.8 11.9 -3.7 43.6 45 56 A C E -D 58 0B 0 228,-2.4 2,-0.4 13,-0.2 13,-0.2 -0.830 13.3-170.3-101.6 110.6 10.4 -0.9 45.5 46 57 A E E -D 57 0B 71 11,-3.4 11,-2.9 -2,-0.7 2,-0.4 -0.802 7.2-159.8 -91.8 141.8 6.6 -0.2 45.3 47 58 A T E -D 56 0B 0 -2,-0.4 204,-1.9 9,-0.2 2,-0.4 -0.955 6.9-171.9-120.6 138.7 5.3 3.0 46.8 48 59 A V E -DF 55 250B 43 7,-2.2 7,-2.9 -2,-0.4 2,-0.4 -0.995 7.4-171.4-126.3 139.4 1.6 3.6 47.8 49 60 A C E +DF 54 249B 0 200,-2.4 200,-3.0 -2,-0.4 2,-0.3 -0.984 16.6 146.4-135.0 144.7 0.3 7.0 48.9 50 61 A K E > -D 53 0B 79 3,-1.6 3,-2.9 -2,-0.4 195,-0.3 -0.880 65.0 -30.0-156.3 176.4 -2.9 8.3 50.3 51 62 A T T 3 S- 0 0 69 193,-0.8 37,-0.1 1,-0.3 3,-0.1 -0.108 130.8 -14.0 -40.3 116.1 -3.9 11.0 52.8 52 63 A G T 3 S+ 0 0 33 35,-0.4 42,-3.6 1,-0.1 2,-0.4 0.457 117.2 105.6 72.9 3.2 -1.0 11.4 55.2 53 64 A M E < +Dg 50 94B 48 -3,-2.9 -3,-1.6 40,-0.2 2,-0.4 -0.956 39.9 177.7-131.6 132.7 0.7 8.1 54.2 54 65 A V E -Dg 49 95B 0 40,-2.5 42,-3.0 -2,-0.4 2,-0.5 -0.996 18.1-169.6-119.6 122.2 3.6 6.9 52.2 55 66 A L E -Dg 48 96B 43 -7,-2.9 -7,-2.2 -2,-0.4 2,-0.5 -0.972 7.6-158.8-111.8 122.2 4.0 3.1 52.2 56 67 A L E +Dg 47 97B 0 40,-2.7 42,-3.1 -2,-0.5 2,-0.3 -0.879 22.6 168.3 -96.4 131.1 7.2 1.4 50.8 57 68 A C E +Dg 46 98B 52 -11,-2.9 -11,-3.4 -2,-0.5 2,-0.3 -0.999 25.5 54.5-147.5 136.8 6.6 -2.2 49.9 58 69 A G E S-Dg 45 99B 5 40,-1.4 42,-2.2 -2,-0.3 2,-0.4 -0.990 77.8 -42.0 139.3-150.4 8.6 -4.8 47.9 59 70 A E E +Dg 44 100B 87 -15,-1.8 -15,-1.7 -2,-0.3 2,-0.4 -0.975 40.4 170.1-134.4 125.3 12.0 -6.4 47.9 60 71 A I E +D 43 0B 12 40,-2.9 2,-0.4 -2,-0.4 -17,-0.2 -0.994 8.2 179.5-136.9 125.3 15.5 -5.0 48.3 61 72 A T E +D 42 0B 50 -19,-2.3 -19,-2.5 -2,-0.4 2,-0.3 -0.973 35.0 133.4-120.9 114.0 18.8 -6.9 48.7 62 73 A S - 0 0 31 -2,-0.4 -2,-0.1 -21,-0.2 -27,-0.0 -0.988 61.2-133.1-160.1 150.5 21.6 -4.4 49.1 63 74 A M S S+ 0 0 152 -2,-0.3 2,-0.1 -29,-0.1 -1,-0.0 0.422 75.4 111.9 -87.7 -1.2 24.7 -3.5 51.1 64 75 A A - 0 0 16 -26,-0.1 2,-0.7 1,-0.1 -2,-0.1 -0.385 63.5-142.1 -75.4 149.3 23.5 0.1 51.4 65 76 A M - 0 0 163 -32,-0.1 2,-0.4 -2,-0.1 -2,-0.1 -0.948 31.2-175.7-108.4 100.8 22.4 1.7 54.6 66 77 A V - 0 0 24 -2,-0.7 2,-1.1 4,-0.0 3,-0.1 -0.872 28.3-142.6-109.9 131.4 19.5 3.9 53.5 67 78 A D > - 0 0 100 -2,-0.4 4,-2.4 1,-0.2 5,-0.2 -0.792 20.2-174.5 -88.6 92.4 17.5 6.3 55.7 68 79 A Y H > S+ 0 0 51 -2,-1.1 4,-2.5 1,-0.2 5,-0.3 0.855 79.4 57.7 -63.8 -35.3 14.0 5.7 54.2 69 80 A Q H > S+ 0 0 76 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.944 111.4 41.7 -56.4 -51.5 12.4 8.4 56.3 70 81 A R H > S+ 0 0 70 2,-0.2 4,-2.8 1,-0.2 5,-0.3 0.904 114.4 50.8 -64.2 -44.2 14.8 11.0 54.9 71 82 A V H X S+ 0 0 25 -4,-2.4 4,-1.6 2,-0.2 -2,-0.2 0.935 115.5 42.4 -62.4 -47.1 14.7 9.8 51.2 72 83 A V H X S+ 0 0 0 -4,-2.5 4,-2.3 -5,-0.2 5,-0.2 0.955 116.9 46.3 -60.8 -53.4 10.9 9.8 51.2 73 84 A R H X S+ 0 0 55 -4,-2.6 4,-2.3 -5,-0.3 -2,-0.2 0.851 111.2 51.8 -65.2 -34.7 10.6 13.2 53.0 74 85 A D H X S+ 0 0 85 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.881 110.1 50.6 -65.8 -38.3 13.2 14.9 50.8 75 86 A T H X S+ 0 0 3 -4,-1.6 4,-2.1 -5,-0.3 -2,-0.2 0.939 111.3 46.0 -67.3 -46.4 11.4 13.7 47.7 76 87 A I H X>S+ 0 0 1 -4,-2.3 5,-1.8 1,-0.2 4,-1.6 0.898 112.0 53.1 -63.6 -41.3 8.0 15.0 48.9 77 88 A K H <5S+ 0 0 122 -4,-2.3 3,-0.3 -5,-0.2 -1,-0.2 0.936 108.6 49.7 -53.2 -50.3 9.7 18.3 49.9 78 89 A H H <5S+ 0 0 108 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.911 107.1 54.1 -58.8 -44.1 11.2 18.6 46.4 79 90 A I H <5S- 0 0 0 -4,-2.1 -1,-0.2 -5,-0.1 -2,-0.2 0.823 121.8-108.9 -61.1 -34.9 7.8 18.0 44.7 80 91 A G T <5S+ 0 0 7 -4,-1.6 2,-1.2 -3,-0.3 -3,-0.2 0.474 72.7 136.1 119.8 8.6 6.4 20.8 46.9 81 92 A Y < + 0 0 1 -5,-1.8 9,-2.4 1,-0.2 -1,-0.2 -0.698 22.8 133.1 -89.0 95.1 4.1 19.2 49.5 82 93 A D E +H 89 0C 61 -2,-1.2 2,-0.3 7,-0.3 7,-0.2 0.091 53.6 44.2-135.8 20.0 5.2 21.2 52.6 83 94 A D E > >S-H 88 0C 73 5,-1.4 3,-1.5 1,-0.1 5,-1.0 -0.935 72.2-120.0-166.4 147.3 2.1 22.3 54.4 84 95 A S G > 5S+ 0 0 99 -2,-0.3 3,-1.6 1,-0.3 -1,-0.1 0.784 109.5 68.0 -58.2 -29.8 -1.3 21.0 55.5 85 96 A A G 3 5S+ 0 0 66 1,-0.3 -1,-0.3 2,-0.1 4,-0.1 0.822 99.3 51.4 -59.9 -30.9 -3.1 23.7 53.4 86 97 A K G < 5S- 0 0 46 -3,-1.5 -1,-0.3 2,-0.2 156,-0.2 0.518 119.8-110.6 -82.8 -7.8 -1.8 21.9 50.4 87 98 A G T < 5S+ 0 0 14 -3,-1.6 -35,-0.4 -4,-0.3 2,-0.3 0.303 93.3 54.1 95.3 -7.8 -3.2 18.5 51.5 88 99 A F E < -H 83 0C 7 -5,-1.0 -5,-1.4 -37,-0.1 2,-0.4 -0.952 57.7-169.2-162.4 137.3 0.2 16.9 52.2 89 100 A D E >> -H 82 0C 12 -2,-0.3 4,-1.5 -7,-0.2 3,-1.1 -0.968 18.8-152.9-137.8 118.5 3.3 17.8 54.2 90 101 A F T 34 S+ 0 0 38 -9,-2.4 -8,-0.1 -2,-0.4 -1,-0.1 0.776 98.9 56.4 -52.5 -31.0 6.8 16.1 54.1 91 102 A K T 34 S+ 0 0 110 1,-0.2 -1,-0.2 -18,-0.0 -9,-0.1 0.773 119.6 24.4 -72.8 -29.9 7.4 17.1 57.7 92 103 A T T <4 S+ 0 0 109 -3,-1.1 -2,-0.2 2,-0.1 -1,-0.2 0.380 90.9 110.8-128.9 2.1 4.3 15.5 59.2 93 104 A C < - 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