==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-JAN-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 15-APR-03 1OFL . COMPND 2 MOLECULE: CHONDROITINASE B; . SOURCE 2 ORGANISM_SCIENTIFIC: PEDOBACTER HEPARINUS; . AUTHOR G.MICHEL,M.CYGLER . 481 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 19091.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 339 70.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 161 33.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 66 13.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 6.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 35 7.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 0 0 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 4 25 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 26 A X 0 0 96 0, 0.0 22,-2.2 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 165.5 53.9 -8.9 25.5 2 27 A V E -a 23 0A 84 20,-0.2 2,-0.4 22,-0.1 22,-0.2 -0.741 360.0-171.4 -82.5 128.0 56.5 -7.2 23.3 3 28 A V E -a 24 0A 5 20,-2.3 22,-3.0 -2,-0.4 3,-0.0 -0.962 16.5-176.9-124.7 143.7 56.0 -7.9 19.6 4 29 A A + 0 0 71 -2,-0.4 2,-0.3 20,-0.2 3,-0.1 0.227 64.0 43.9-126.2 8.3 58.5 -7.0 16.8 5 30 A S S > S- 0 0 47 1,-0.1 4,-2.3 22,-0.1 5,-0.2 -0.975 82.2-107.8-146.2 163.7 56.7 -8.1 13.6 6 31 A N H > S+ 0 0 35 -2,-0.3 4,-2.8 1,-0.2 5,-0.2 0.951 117.9 50.0 -52.8 -49.4 53.3 -8.0 11.9 7 32 A E H > S+ 0 0 143 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.878 111.4 46.8 -62.9 -41.5 52.7 -11.7 12.5 8 33 A T H > S+ 0 0 62 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.866 111.0 51.9 -68.7 -37.0 53.6 -11.6 16.1 9 34 A L H X S+ 0 0 0 -4,-2.3 4,-2.2 2,-0.2 -2,-0.2 0.928 108.9 51.6 -58.1 -48.4 51.4 -8.6 16.7 10 35 A Y H X S+ 0 0 50 -4,-2.8 4,-1.0 1,-0.2 -2,-0.2 0.922 112.5 46.3 -54.6 -44.2 48.5 -10.4 15.0 11 36 A Q H >X S+ 0 0 95 -4,-2.0 4,-1.0 1,-0.2 3,-0.9 0.956 111.0 48.9 -66.4 -47.7 49.0 -13.4 17.3 12 37 A V H >X S+ 0 0 17 -4,-2.4 4,-1.5 1,-0.3 3,-0.6 0.864 108.2 55.0 -66.9 -35.0 49.3 -11.6 20.6 13 38 A V H 3< S+ 0 0 4 -4,-2.2 25,-0.4 1,-0.2 -1,-0.3 0.768 102.7 57.0 -69.0 -23.5 46.2 -9.5 19.9 14 39 A K H << S+ 0 0 138 -4,-1.0 -1,-0.2 -3,-0.9 -2,-0.2 0.740 117.7 33.8 -70.2 -24.8 44.2 -12.7 19.4 15 40 A E H << S+ 0 0 114 -4,-1.0 -2,-0.2 -3,-0.6 -1,-0.2 0.618 85.2 122.7-105.9 -14.2 45.2 -13.9 22.9 16 41 A V < - 0 0 9 -4,-1.5 23,-0.1 -5,-0.2 3,-0.1 -0.204 47.1-149.9 -66.0 143.4 45.4 -10.7 24.9 17 42 A K > - 0 0 150 1,-0.2 3,-2.4 21,-0.1 23,-0.1 -0.643 35.5 -69.0-107.0 162.2 43.1 -10.5 28.0 18 43 A P T 3 S+ 0 0 46 0, 0.0 28,-0.2 0, 0.0 -1,-0.2 -0.239 126.3 24.5 -47.8 137.1 41.4 -7.6 29.8 19 44 A G T 3 S+ 0 0 41 25,-1.0 27,-0.2 26,-0.8 21,-0.1 0.303 95.2 145.0 84.6 -0.8 44.0 -5.4 31.4 20 45 A G < - 0 0 17 -3,-2.4 27,-2.3 24,-0.2 2,-0.4 -0.147 39.3-149.8 -70.7 160.0 46.6 -6.7 28.9 21 46 A L E - b 0 47A 76 25,-0.2 2,-0.5 -3,-0.1 27,-0.2 -0.977 8.8-170.5-137.7 115.0 49.5 -4.5 27.5 22 47 A V E - b 0 48A 0 25,-3.1 27,-3.0 -2,-0.4 2,-0.5 -0.948 8.9-165.7-109.1 118.7 50.9 -5.2 24.0 23 48 A Q E -ab 2 49A 49 -22,-2.2 -20,-2.3 -2,-0.5 2,-0.5 -0.957 11.0-143.4-110.2 130.6 54.0 -3.2 23.2 24 49 A I E -ab 3 50A 0 25,-2.7 27,-2.7 -2,-0.5 28,-0.5 -0.785 21.1-127.8 -98.5 122.3 55.3 -2.8 19.7 25 50 A A - 0 0 18 -22,-3.0 -1,-0.0 -2,-0.5 25,-0.0 -0.273 42.8 -75.3 -63.5 155.5 59.1 -2.9 19.4 26 51 A D S S+ 0 0 89 30,-0.1 2,-0.3 24,-0.1 30,-0.2 -0.141 88.9 76.7 -50.6 135.2 60.9 -0.1 17.5 27 52 A G E S-n 56 0B 26 28,-2.7 30,-2.2 -3,-0.1 2,-0.4 -0.921 78.8 -63.4 153.8-175.8 60.4 -0.5 13.8 28 53 A T E -n 57 0B 91 -2,-0.3 2,-0.7 28,-0.2 30,-0.2 -0.898 30.5-160.3-109.8 132.9 58.4 -0.2 10.7 29 54 A Y E > -n 58 0B 5 28,-3.2 30,-1.9 -2,-0.4 3,-0.9 -0.858 19.5-163.5-116.6 90.6 55.2 -2.3 10.3 30 55 A K E 3 -n 59 0B 124 -2,-0.7 30,-0.2 1,-0.3 3,-0.1 -0.605 67.7 -2.8 -90.7 129.7 54.5 -2.3 6.6 31 56 A D T 3 S+ 0 0 58 28,-2.2 -1,-0.3 -2,-0.3 29,-0.2 0.757 89.2 179.6 65.1 25.5 51.1 -3.3 5.2 32 57 A V < - 0 0 0 -3,-0.9 31,-2.4 27,-0.6 2,-0.6 -0.369 20.1-163.6 -65.2 134.2 50.1 -4.0 8.8 33 58 A Q E -a 63 0C 71 29,-0.2 2,-0.8 -3,-0.1 31,-0.2 -0.809 12.1-176.1-119.7 80.8 46.4 -5.3 9.2 34 59 A L E +a 64 0C 0 29,-2.2 31,-2.7 -2,-0.6 2,-0.5 -0.767 7.1 171.9 -90.1 111.3 45.7 -4.8 12.8 35 60 A I E -a 65 0C 54 -2,-0.8 2,-0.7 29,-0.2 31,-0.2 -0.983 12.3-166.7-121.1 115.2 42.2 -6.1 13.7 36 61 A V E +a 66 0C 0 29,-2.8 31,-2.4 -2,-0.5 32,-2.0 -0.900 20.5 158.8-109.8 104.4 41.5 -6.2 17.4 37 62 A S + 0 0 77 -2,-0.7 32,-0.2 30,-0.2 -1,-0.2 0.720 47.3 88.4 -95.5 -27.3 38.4 -8.3 18.1 38 63 A N - 0 0 58 -25,-0.4 2,-0.4 30,-0.1 30,-0.4 -0.266 69.0-135.7 -70.4 162.2 38.9 -9.1 21.8 39 64 A S - 0 0 52 29,-0.2 31,-0.2 -23,-0.1 2,-0.1 -0.910 7.3-148.3-121.7 147.4 37.6 -6.8 24.5 40 65 A G - 0 0 5 29,-2.8 2,-0.3 -2,-0.4 29,-0.2 -0.136 28.8-118.3 -83.8-165.1 38.9 -5.3 27.7 41 66 A K B > -L 44 0D 133 3,-2.2 3,-3.0 29,-0.2 -22,-0.1 -0.924 39.3 -72.1-134.0 159.3 36.6 -4.5 30.6 42 67 A S T 3 S+ 0 0 99 -2,-0.3 60,-0.0 1,-0.3 0, 0.0 -0.348 126.6 7.9 -52.8 127.1 35.6 -1.4 32.4 43 68 A G T 3 S+ 0 0 78 1,-0.0 -1,-0.3 -3,-0.0 27,-0.0 0.359 125.2 71.9 74.9 -2.8 38.7 -0.5 34.5 44 69 A L B < +L 41 0D 88 -3,-3.0 -3,-2.2 2,-0.0 -25,-1.0 -0.492 68.5 171.5-135.4 64.4 40.7 -3.2 32.7 45 70 A P - 0 0 44 0, 0.0 -26,-0.8 0, 0.0 2,-0.5 -0.194 34.9-120.6 -68.9 162.9 41.3 -1.9 29.2 46 71 A I E - c 0 71A 0 24,-2.3 26,-2.4 -28,-0.2 2,-0.5 -0.957 29.6-156.0-102.2 128.2 43.6 -3.6 26.7 47 72 A T E -bc 21 72A 27 -27,-2.3 -25,-3.1 -2,-0.5 2,-0.5 -0.939 14.0-174.1-111.2 128.3 46.4 -1.3 25.6 48 73 A I E +bc 22 73A 1 24,-3.2 26,-2.4 -2,-0.5 2,-0.3 -0.993 29.3 148.8-118.4 115.5 48.3 -1.7 22.3 49 74 A K E -bc 23 74A 30 -27,-3.0 -25,-2.7 -2,-0.5 2,-0.3 -0.945 52.8 -92.4-144.9 162.7 51.1 0.8 22.2 50 75 A A E -b 24 0A 0 24,-1.4 -25,-0.2 -2,-0.3 -24,-0.1 -0.590 30.2-137.5 -70.0 139.5 54.5 1.5 20.9 51 76 A L S S+ 0 0 67 -27,-2.7 -1,-0.2 1,-0.3 -26,-0.1 0.937 104.9 20.9 -59.5 -40.7 57.2 0.5 23.5 52 77 A N S > S- 0 0 71 -28,-0.5 3,-2.3 23,-0.1 -1,-0.3 -0.867 92.9-139.1-129.8 94.1 58.9 3.8 22.5 53 78 A P T 3 S+ 0 0 27 0, 0.0 23,-0.1 0, 0.0 22,-0.1 -0.322 91.6 39.5 -57.7 136.2 56.4 6.2 20.9 54 79 A G T 3 S+ 0 0 17 21,-0.7 22,-0.1 2,-0.3 21,-0.0 0.085 105.9 71.5 99.8 -13.8 58.0 8.0 18.0 55 80 A K S < S+ 0 0 121 -3,-2.3 -28,-2.7 20,-0.2 2,-0.5 0.410 79.0 81.0-113.2 2.1 59.8 4.8 17.0 56 81 A V E -n 27 0B 0 19,-0.4 21,-2.0 -30,-0.2 2,-0.4 -0.959 56.5-173.1-114.3 125.5 56.9 2.7 15.6 57 82 A F E -no 28 77B 41 -30,-2.2 -28,-3.2 -2,-0.5 2,-0.6 -0.951 14.8-159.4-119.6 127.9 55.6 3.4 12.1 58 83 A F E +no 29 78B 0 19,-2.6 21,-1.5 -2,-0.4 2,-0.2 -0.955 37.1 156.1-103.0 116.4 52.5 1.9 10.5 59 84 A T E +n 30 0B 8 -30,-1.9 -28,-2.2 -2,-0.6 -27,-0.6 -0.697 24.9 29.6-133.6-178.8 53.1 2.2 6.8 60 85 A G E S- o 0 81B 3 20,-2.5 22,-2.2 19,-0.3 2,-1.8 -0.262 116.1 -7.0 68.1-147.3 52.2 0.8 3.4 61 86 A D S S+ 0 0 63 21,-0.3 2,-0.2 20,-0.2 -1,-0.2 -0.600 96.7 155.2 -90.0 81.1 48.8 -0.8 2.6 62 87 A A + 0 0 1 -2,-1.8 2,-0.3 -4,-0.1 -29,-0.2 -0.556 24.5 173.0-111.2 162.8 47.7 -0.7 6.3 63 88 A K E -a 33 0C 54 -31,-2.4 -29,-2.2 -2,-0.2 2,-0.4 -0.941 14.2-154.6-164.3 153.1 44.5 -0.6 8.3 64 89 A V E -ab 34 96C 2 31,-2.4 33,-2.6 -2,-0.3 2,-0.4 -0.998 7.8-172.6-128.4 137.4 43.4 -0.8 11.9 65 90 A E E -ab 35 97C 22 -31,-2.7 -29,-2.8 -2,-0.4 2,-0.9 -0.986 10.1-162.5-128.8 121.4 40.1 -2.0 13.2 66 91 A L E +ab 36 98C 1 31,-2.7 33,-2.7 -2,-0.4 34,-2.0 -0.873 29.3 153.2-101.6 97.2 39.1 -1.7 16.8 67 92 A R + 0 0 95 -31,-2.4 -30,-0.2 -2,-0.9 -1,-0.2 0.765 50.4 70.3 -98.8 -32.1 36.2 -4.1 17.0 68 93 A G S S- 0 0 3 -32,-2.0 32,-0.4 -30,-0.4 2,-0.3 -0.091 85.0-110.1 -69.4 176.1 36.4 -5.1 20.7 69 94 A E S S+ 0 0 82 -29,-0.2 -29,-2.8 1,-0.2 33,-0.2 -0.748 88.2 30.4-109.2 161.2 35.4 -2.7 23.5 70 95 A H S S+ 0 0 24 31,-1.3 -24,-2.3 -2,-0.3 2,-0.3 0.915 81.9 146.9 58.1 47.5 37.7 -1.1 26.1 71 96 A L E -c 46 0A 0 30,-0.3 33,-2.3 -26,-0.2 2,-0.4 -0.866 34.2-158.8-114.4 147.9 40.7 -0.9 23.9 72 97 A I E -cd 47 104A 29 -26,-2.4 -24,-3.2 -2,-0.3 2,-0.5 -0.998 1.7-167.0-126.5 124.3 43.4 1.8 23.8 73 98 A L E +cd 48 105A 1 31,-2.6 33,-2.6 -2,-0.4 2,-0.4 -0.970 23.8 175.4-110.2 122.9 45.7 2.4 20.8 74 99 A E E +cd 49 106A 37 -26,-2.4 -24,-1.4 -2,-0.5 33,-0.2 -0.987 41.6 6.1-139.1 138.1 48.6 4.6 21.7 75 100 A G S S+ 0 0 0 31,-1.4 -21,-0.7 -2,-0.4 -19,-0.4 0.735 73.8 146.1 77.6 32.7 51.8 6.1 20.3 76 101 A I - 0 0 0 30,-0.3 33,-2.3 -23,-0.1 2,-0.6 -0.814 36.6-151.9-105.2 138.7 51.6 5.1 16.6 77 102 A W E -op 57 109B 46 -21,-2.0 -19,-2.6 -2,-0.4 2,-0.6 -0.954 9.2-160.3-110.0 118.8 52.9 7.1 13.7 78 103 A F E +op 58 110B 0 31,-3.4 33,-2.0 -2,-0.6 2,-0.3 -0.866 34.7 127.3 -99.7 117.7 51.1 6.5 10.4 79 104 A K E + 0 0 59 -21,-1.5 -19,-0.3 -2,-0.6 34,-0.1 -0.937 45.2 43.7-154.4 174.4 53.1 7.6 7.3 80 105 A D E S+ 0 0 115 31,-0.4 -20,-2.5 32,-0.3 34,-0.1 0.851 75.5 173.9 51.9 44.0 54.3 6.3 4.0 81 106 A G E -o 60 0B 10 32,-2.5 -20,-0.2 31,-0.3 -1,-0.1 -0.265 27.8-179.2 -83.1 167.2 51.0 4.6 3.2 82 107 A N + 0 0 114 -22,-2.2 -21,-0.3 32,-0.1 32,-0.1 -0.091 15.5 165.1-164.0 47.2 49.9 2.9 -0.0 83 108 A R - 0 0 5 -23,-0.4 2,-0.4 1,-0.1 32,-0.3 -0.281 51.7 -90.7 -70.2 155.1 46.4 1.6 0.3 84 109 A A > - 0 0 29 1,-0.2 3,-1.9 3,-0.1 4,-0.4 -0.544 28.3-147.1 -73.7 122.6 44.6 0.6 -2.9 85 110 A I G > S+ 0 0 75 -2,-0.4 3,-0.7 1,-0.3 32,-0.3 0.838 98.4 54.1 -63.9 -28.6 42.8 3.6 -4.4 86 111 A Q G 3 S+ 0 0 169 1,-0.2 -1,-0.3 30,-0.1 -2,-0.1 0.469 105.9 56.4 -78.7 -1.7 40.1 1.4 -5.8 87 112 A A G < S+ 0 0 69 -3,-1.9 2,-0.4 1,-0.0 -1,-0.2 0.419 97.8 60.9-111.5 -3.9 39.5 -0.2 -2.4 88 113 A W < - 0 0 45 -3,-0.7 29,-0.4 -4,-0.4 2,-0.3 -0.975 58.6-172.8-128.4 143.4 38.7 2.8 -0.2 89 114 A K > - 0 0 139 -2,-0.4 3,-1.6 4,-0.2 30,-0.3 -0.954 33.2-101.7-133.7 155.7 35.9 5.4 -0.2 90 115 A S T 3 S+ 0 0 30 -2,-0.3 59,-0.1 1,-0.3 27,-0.1 -0.439 113.3 30.5 -59.5 148.0 34.8 8.6 1.4 91 116 A H T 3 S+ 0 0 60 1,-0.3 -1,-0.3 59,-0.1 68,-0.3 0.511 105.4 101.3 71.5 10.5 32.0 7.8 3.9 92 117 A G S < S- 0 0 7 -3,-1.6 27,-0.3 1,-0.2 -1,-0.3 -0.302 87.8 -52.0-104.2-168.2 33.6 4.3 4.5 93 118 A P - 0 0 47 0, 0.0 -1,-0.2 0, 0.0 -4,-0.2 -0.315 59.9-117.8 -63.3 149.7 35.8 3.2 7.4 94 119 A G - 0 0 2 2,-0.3 -30,-0.3 24,-0.2 26,-0.2 -0.279 32.1 -96.5 -77.0 171.2 38.8 5.3 8.3 95 120 A L S S+ 0 0 0 24,-1.8 -31,-2.4 1,-0.3 2,-0.6 0.919 131.9 35.4 -51.5 -47.6 42.4 4.2 8.2 96 121 A V E S-bc 64 121C 0 24,-2.3 26,-2.4 -33,-0.2 2,-0.5 -0.980 88.8-171.0-102.2 120.6 41.7 3.6 11.8 97 122 A A E -bc 65 122C 1 -33,-2.6 -31,-2.7 -2,-0.6 2,-0.7 -0.955 9.1-157.2-114.7 122.2 38.1 2.4 12.1 98 123 A I E +bc 66 123C 0 24,-2.8 26,-2.5 -2,-0.5 -31,-0.2 -0.876 23.1 162.0-103.1 113.4 36.5 2.1 15.6 99 124 A Y + 0 0 29 -33,-2.7 -32,-0.2 -2,-0.7 27,-0.2 0.654 55.9 68.0-103.6 -23.1 33.6 -0.4 15.6 100 125 A G S S- 0 0 6 -34,-2.0 3,-0.4 -32,-0.4 -32,-0.1 -0.649 80.6-111.9 -96.0 164.9 33.4 -1.0 19.3 101 126 A S S S+ 0 0 14 -2,-0.2 -31,-1.3 1,-0.2 -30,-0.3 -0.293 91.1 32.8 -85.3 167.7 32.3 1.2 22.3 102 127 A Y S S+ 0 0 109 31,-2.2 2,-0.3 -33,-0.2 33,-0.2 0.814 84.6 143.5 57.5 36.0 34.6 2.6 25.1 103 128 A N - 0 0 1 -3,-0.4 33,-2.4 30,-0.3 2,-0.4 -0.787 32.3-161.4-108.2 150.4 37.7 2.8 22.8 104 129 A R E -de 72 136A 76 -33,-2.3 -31,-2.6 -2,-0.3 2,-0.5 -0.997 11.7-166.7-134.4 133.5 40.4 5.4 22.8 105 130 A I E +de 73 137A 0 31,-2.4 33,-2.4 -2,-0.4 2,-0.3 -0.991 28.3 171.2-117.1 121.5 43.0 6.4 20.2 106 131 A T E +de 74 138A 8 -33,-2.6 -31,-1.4 -2,-0.5 -30,-0.3 -0.987 47.3 4.5-137.2 144.1 45.7 8.6 21.8 107 132 A A S S+ 0 0 0 31,-1.4 2,-0.3 -2,-0.3 -32,-0.3 0.858 84.3 142.2 56.3 43.3 49.0 10.2 21.1 108 133 A C - 0 0 0 30,-0.3 33,-2.1 -33,-0.2 2,-0.4 -0.848 42.0-141.8-114.3 152.3 49.1 9.0 17.5 109 134 A V E -pq 77 141B 0 -33,-2.3 -31,-3.4 -2,-0.3 2,-0.4 -0.947 12.8-175.1-116.6 130.8 50.4 10.9 14.4 110 135 A F E +pq 78 142B 0 31,-2.6 33,-2.7 -2,-0.4 2,-0.5 -0.984 14.3 174.0-123.5 115.8 48.7 10.8 10.9 111 136 A D E - q 0 143B 13 -33,-2.0 -31,-0.4 -2,-0.4 33,-0.2 -0.943 65.0 -42.5-138.5 108.5 50.8 12.7 8.4 112 137 A C S S- 0 0 10 31,-2.8 -32,-0.3 -2,-0.5 -31,-0.3 0.880 75.7-177.9 42.8 55.7 50.0 12.7 4.6 113 138 A F - 0 0 2 30,-0.2 -32,-2.5 -34,-0.1 2,-0.2 0.916 40.6 -53.8 -60.9 -54.6 49.3 9.0 4.9 114 139 A D - 0 0 2 2,-0.2 32,-0.4 -34,-0.1 -32,-0.1 -0.833 49.4 -86.8-163.8-161.6 48.4 8.0 1.3 115 140 A E S S+ 0 0 36 -32,-0.3 2,-0.4 -2,-0.2 33,-0.2 0.245 81.4 112.2-109.4 5.1 46.3 8.7 -1.8 116 141 A A S S- 0 0 0 31,-0.1 2,-0.3 1,-0.0 -2,-0.2 -0.719 71.1-118.9 -88.0 128.4 43.3 6.5 -0.8 117 142 A N + 0 0 34 -29,-0.4 2,-0.3 -2,-0.4 32,-0.2 -0.549 66.4 96.1 -71.9 123.9 40.0 8.4 -0.1 118 143 A S S S- 0 0 0 30,-1.5 -28,-0.2 -2,-0.3 -24,-0.2 -0.877 74.5 -81.8 175.0 165.5 38.8 7.9 3.5 119 144 A A - 0 0 0 -27,-0.3 -24,-1.8 -30,-0.3 32,-0.2 -0.348 32.9-125.8 -71.0 166.1 39.0 9.6 6.9 120 145 A Y S S+ 0 0 0 31,-2.1 -24,-2.3 1,-0.3 2,-0.4 0.869 96.1 13.3 -79.0 -38.1 42.0 9.1 9.0 121 146 A I E S+cd 96 152C 0 30,-2.0 32,-1.6 -26,-0.2 2,-0.3 -0.999 71.6 174.6-135.8 137.2 39.8 7.9 12.0 122 147 A T E -cd 97 153C 0 -26,-2.4 -24,-2.8 -2,-0.4 2,-0.5 -0.955 31.5-139.6-126.4 155.2 36.1 6.9 12.1 123 148 A T E -cd 98 154C 0 30,-1.8 32,-1.5 -2,-0.3 2,-0.4 -0.984 42.9-168.2 -96.6 132.6 33.7 5.5 14.5 124 149 A S - 0 0 10 -26,-2.5 2,-0.2 -2,-0.5 34,-0.1 -0.937 22.8-118.9-129.9 144.5 31.8 3.1 12.2 125 150 A L - 0 0 35 -2,-0.4 6,-0.2 32,-0.1 -25,-0.1 -0.489 32.0-123.8 -76.5 145.7 28.7 1.0 12.4 126 151 A T > - 0 0 27 4,-1.6 3,-2.4 -27,-0.2 -1,-0.1 -0.349 34.7 -95.9 -76.8 169.3 29.0 -2.8 12.2 127 152 A E T 3 S+ 0 0 197 1,-0.3 -1,-0.1 2,-0.1 -2,-0.1 0.807 126.7 57.1 -57.2 -28.1 27.1 -4.6 9.5 128 153 A D T 3 S- 0 0 102 2,-0.1 -1,-0.3 1,-0.0 -2,-0.0 0.379 121.6-107.9 -87.0 5.5 24.3 -5.4 12.0 129 154 A G < + 0 0 40 -3,-2.4 2,-0.2 1,-0.3 -2,-0.1 0.502 62.2 156.7 90.3 7.8 23.9 -1.7 12.6 130 155 A K - 0 0 141 1,-0.1 -4,-1.6 -6,-0.0 -1,-0.3 -0.457 33.6-140.3 -73.0 137.9 25.4 -1.4 16.1 131 156 A V - 0 0 28 -6,-0.2 -6,-0.1 -2,-0.2 25,-0.1 -0.828 10.4-127.3-102.5 121.1 26.7 2.1 16.9 132 157 A P - 0 0 1 0, 0.0 2,-0.3 0, 0.0 3,-0.1 -0.429 33.7-175.2 -63.0 140.7 29.9 2.7 18.8 133 158 A Q + 0 0 65 1,-0.1 -31,-2.2 -2,-0.1 -30,-0.3 -0.904 51.0 25.3-133.8 160.5 29.5 5.0 21.8 134 159 A H S S+ 0 0 68 37,-2.8 2,-0.2 -2,-0.3 39,-0.2 0.823 77.3 150.9 61.2 36.3 31.7 6.6 24.5 135 160 A C - 0 0 4 36,-0.3 39,-2.2 -33,-0.2 2,-0.4 -0.669 30.9-150.0 -95.6 157.5 34.9 6.6 22.4 136 161 A R E -ef 104 174A 63 -33,-2.4 -31,-2.4 -2,-0.2 2,-0.5 -0.994 14.1-173.3-130.2 138.8 37.8 9.2 22.7 137 162 A I E +ef 105 175A 3 37,-2.5 39,-2.2 -2,-0.4 2,-0.3 -0.996 31.4 155.5-123.0 117.0 40.2 10.6 20.1 138 163 A D E +ef 106 176A 0 -33,-2.4 -31,-1.4 -2,-0.5 -30,-0.3 -0.997 46.0 13.5-149.9 149.5 42.8 12.7 21.9 139 164 A H S S+ 0 0 48 37,-1.4 2,-0.3 -2,-0.3 39,-0.2 0.802 85.5 138.7 57.6 35.6 46.4 14.1 21.6 140 165 A C - 0 0 1 36,-0.4 39,-2.2 -33,-0.2 2,-0.4 -0.784 46.2-142.2-110.7 153.5 46.6 13.1 18.0 141 166 A S E -qr 109 179B 0 -33,-2.1 -31,-2.6 -2,-0.3 2,-0.5 -0.969 12.4-171.9-118.1 131.2 48.0 15.1 15.1 142 167 A F E +qr 110 180B 0 37,-3.1 39,-2.2 -2,-0.4 2,-0.3 -0.935 20.4 164.7-126.2 104.3 46.4 15.1 11.7 143 168 A T E +qr 111 181B 1 -33,-2.7 -31,-2.8 -2,-0.5 -30,-0.2 -0.916 48.4 3.0-131.4 150.9 48.5 16.8 9.0 144 169 A D - 0 0 0 37,-1.9 2,-0.4 -2,-0.3 38,-0.2 0.786 66.4-177.1 54.7 40.0 48.8 17.2 5.2 145 170 A K + 0 0 0 36,-0.2 -1,-0.2 -3,-0.1 -30,-0.1 -0.571 8.3 179.0 -71.1 122.0 45.8 15.1 4.4 146 171 A I + 0 0 0 -2,-0.4 2,-0.3 -32,-0.4 -1,-0.1 0.150 49.5 83.3-111.9 18.1 45.6 14.9 0.6 147 172 A T S S- 0 0 0 -29,-0.1 -31,-0.1 2,-0.1 -30,-0.1 -0.814 81.0 -93.6-122.8 159.3 42.6 12.7 0.1 148 173 A F S S+ 0 0 18 -2,-0.3 -30,-1.5 -33,-0.2 42,-0.2 -0.174 80.3 49.5 -68.3 164.0 38.9 13.2 0.1 149 174 A D S S- 0 0 4 40,-2.0 -2,-0.1 -32,-0.2 -31,-0.1 0.082 93.6 -58.3 88.5 163.2 36.5 12.8 3.2 150 175 A Q - 0 0 11 1,-0.1 -30,-0.3 -31,-0.1 42,-0.2 -0.106 40.4-119.1 -58.6 160.5 36.9 14.3 6.6 151 176 A V S S+ 0 0 0 40,-1.3 -31,-2.1 41,-0.8 -30,-2.0 0.901 103.6 14.6 -62.7 -46.9 39.9 13.8 8.9 152 177 A I E -de 121 193C 0 40,-2.2 42,-2.4 -32,-0.2 2,-0.5 -0.999 66.6-170.4-129.6 130.6 37.5 12.2 11.4 153 178 A N E -de 122 194C 0 -32,-1.6 -30,-1.8 -2,-0.4 2,-0.6 -0.997 6.5-162.3-114.6 135.4 33.9 11.0 10.9 154 179 A L E -de 123 195C 2 40,-2.7 42,-2.6 -2,-0.5 2,-0.4 -0.960 22.1-162.4-112.2 110.6 31.9 10.1 14.0 155 180 A N + 0 0 12 -32,-1.5 3,-0.1 -2,-0.6 -2,-0.0 -0.784 36.0 161.0-108.5 134.4 28.9 8.0 12.7 156 181 A N S S+ 0 0 3 -2,-0.4 2,-0.3 1,-0.2 -1,-0.1 0.274 75.4 33.9-124.8 5.9 25.6 7.0 14.2 157 182 A T S S- 0 0 13 11,-0.2 2,-0.2 44,-0.0 -1,-0.2 -0.980 83.7-105.3-145.5 159.5 23.8 6.0 11.0 158 183 A A - 0 0 72 -2,-0.3 2,-0.1 1,-0.1 39,-0.0 -0.574 51.6 -95.3 -75.3 146.3 24.6 4.5 7.6 159 184 A R + 0 0 159 -68,-0.3 2,-0.3 -2,-0.2 -1,-0.1 -0.411 60.9 152.8 -63.7 137.6 24.7 7.0 4.8 160 185 A A - 0 0 47 -2,-0.1 3,-0.1 -3,-0.1 -3,-0.0 -0.966 63.3-107.8-157.8 162.2 21.4 7.1 3.0 161 186 A I S S+ 0 0 163 -2,-0.3 -2,-0.0 1,-0.1 -1,-0.0 0.701 74.9 165.0 -70.6 -16.7 19.4 9.6 0.9 162 187 A K + 0 0 69 1,-0.1 -1,-0.1 36,-0.0 -3,-0.0 0.253 37.1 156.0 54.4-158.3 17.3 9.5 4.2 163 188 A D + 0 0 139 1,-0.3 2,-0.6 3,-0.1 -1,-0.1 0.558 33.4 133.8 105.1 19.8 14.6 11.7 5.6 164 189 A G - 0 0 43 2,-0.2 2,-0.3 1,-0.1 -1,-0.3 -0.895 66.4-117.6-102.8 119.2 12.7 9.3 7.9 165 190 A S S S+ 0 0 105 -2,-0.6 2,-0.8 1,-0.1 -1,-0.1 0.425 89.2 94.7 -32.5 -18.7 12.0 10.9 11.4 166 191 A V - 0 0 116 -2,-0.3 -2,-0.2 35,-0.0 35,-0.1 -0.694 60.0-170.0 -87.7 105.7 14.1 8.2 13.2 167 192 A G - 0 0 26 -2,-0.8 34,-0.2 33,-0.4 32,-0.1 -0.265 29.3 -80.6 -91.2 173.4 17.7 9.5 13.8 168 193 A G - 0 0 4 30,-0.2 34,-2.4 1,-0.1 -1,-0.2 -0.310 53.7-101.6 -68.8 153.4 20.9 7.9 15.0 169 194 A P - 0 0 63 0, 0.0 -1,-0.1 0, 0.0 32,-0.0 -0.385 47.1 -77.8 -75.8 157.8 21.4 7.3 18.8 170 195 A A - 0 0 11 1,-0.1 33,-0.2 -2,-0.1 34,-0.2 -0.220 39.3-165.0 -52.1 137.6 23.5 9.6 21.1 171 196 A M - 0 0 0 32,-2.2 -37,-2.8 31,-0.2 -36,-0.3 0.823 6.3-158.7 -98.1 -35.9 27.3 8.8 20.7 172 197 A Y + 0 0 45 31,-1.6 33,-0.2 -39,-0.2 32,-0.1 0.816 35.3 153.7 56.7 38.4 28.9 10.4 23.7 173 198 A H - 0 0 5 30,-0.3 33,-2.6 -39,-0.2 2,-0.4 -0.426 33.9-144.3 -85.3 167.6 32.4 10.6 22.2 174 199 A R E -fg 136 206A 75 -39,-2.2 -37,-2.5 31,-0.2 2,-0.5 -0.999 12.4-173.7-131.5 133.1 35.1 13.1 23.0 175 200 A V E +fg 137 207A 1 31,-2.3 33,-1.8 -2,-0.4 2,-0.3 -0.983 29.1 155.0-119.0 115.2 37.6 14.6 20.5 176 201 A D E +fg 138 208A 0 -39,-2.2 -37,-1.4 -2,-0.5 -36,-0.4 -0.987 46.7 12.8-142.2 152.9 40.2 16.7 22.5 177 202 A H S S+ 0 0 39 31,-1.0 2,-0.3 32,-0.5 33,-0.2 0.826 82.5 143.7 57.3 35.6 43.7 18.0 22.3 178 203 A C - 0 0 0 -39,-0.2 33,-2.7 30,-0.2 2,-0.4 -0.790 43.2-140.2-105.2 159.2 44.1 17.1 18.6 179 204 A F E -rs 141 211B 1 -39,-2.2 -37,-3.1 -2,-0.3 2,-0.5 -0.945 17.5-173.7-117.7 129.7 45.9 19.2 16.0 180 205 A F E +rs 142 212B 0 31,-2.4 33,-2.6 -2,-0.4 2,-0.3 -0.979 17.6 151.2-128.3 124.4 44.5 19.7 12.5 181 206 A S E +r 143 0B 0 -39,-2.2 -37,-1.9 -2,-0.5 34,-0.3 -0.850 18.2 153.6-153.3 112.9 46.3 21.3 9.5 182 207 A N E - s 0 215B 0 32,-1.2 34,-2.3 -2,-0.3 35,-0.3 -0.992 39.0-103.7-149.5 143.4 45.4 20.2 6.1 183 208 A P - 0 0 4 0, 0.0 2,-0.3 0, 0.0 279,-0.0 -0.236 42.7 -90.4 -77.3 157.6 45.4 21.7 2.5 184 209 A Q - 0 0 105 1,-0.0 33,-0.2 35,-0.0 34,-0.2 -0.444 39.8-165.9 -68.1 124.8 42.5 22.9 0.5 185 210 A K - 0 0 8 32,-2.9 2,-0.3 -2,-0.3 4,-0.2 -0.631 30.9 -91.4 -97.1 165.7 40.8 20.4 -1.8 186 211 A P S S- 0 0 67 0, 0.0 -1,-0.1 0, 0.0 31,-0.0 -0.564 78.4 -24.7 -78.9 139.0 38.4 21.2 -4.6 187 212 A G S S- 0 0 66 -2,-0.3 2,-1.9 1,-0.2 32,-0.4 -0.215 121.8 -10.4 75.9-151.2 34.6 21.4 -3.9 188 213 A N S S+ 0 0 145 1,-0.2 -1,-0.2 30,-0.1 -39,-0.1 -0.534 83.5 153.4 -88.0 73.5 32.7 19.6 -1.2 189 214 A A - 0 0 5 -2,-1.9 -40,-2.0 -4,-0.2 -1,-0.2 0.427 56.7 -88.3 -93.0 -6.7 35.8 17.6 -0.4 190 215 A G - 0 0 5 -42,-0.2 -1,-0.2 -3,-0.1 -5,-0.2 0.364 44.5-146.7 95.4 129.8 35.4 16.6 3.3 191 216 A G - 0 0 2 26,-0.1 -40,-1.3 -39,-0.1 30,-0.2 0.385 37.6 -61.5-103.8-136.2 36.6 18.7 6.2 192 217 A G S S- 0 0 0 29,-1.5 -40,-2.2 28,-0.7 -41,-0.8 0.951 107.2 -1.8 -83.0 -68.4 38.1 18.3 9.7 193 218 A I E -ef 152 222C 0 28,-1.3 30,-3.0 -42,-0.2 2,-0.4 -0.987 54.3-167.1-132.4 134.8 35.4 16.5 11.6 194 219 A R E -ef 153 223C 2 -42,-2.4 -40,-2.7 -2,-0.4 2,-0.5 -0.978 6.0-170.2-113.1 137.3 31.9 15.3 10.7 195 220 A I E -ef 154 224C 0 28,-1.6 30,-2.1 -2,-0.4 -40,-0.2 -0.956 58.0 -27.3-128.0 109.5 29.5 14.2 13.6 196 221 A G - 0 0 0 -42,-2.6 30,-0.2 -2,-0.5 -42,-0.1 -0.211 62.8-114.2 80.1-176.1 26.3 12.5 12.4 197 222 A Y S S+ 0 0 11 28,-0.5 2,-0.3 1,-0.3 29,-0.2 0.633 77.2 20.0-126.2 -38.8 24.5 13.0 9.1 198 223 A Y S > S- 0 0 62 27,-0.4 3,-2.2 49,-0.1 -1,-0.3 -0.905 79.6 -93.7-144.9 170.2 21.0 14.6 9.5 199 224 A R T 3 S+ 0 0 72 1,-0.3 50,-0.4 -2,-0.3 28,-0.1 0.706 115.3 58.0 -71.3 -18.6 18.9 16.6 11.9 200 225 A N T 3 S+ 0 0 49 48,-0.1 -33,-0.4 26,-0.1 -1,-0.3 0.623 84.7 103.5 -80.6 -11.5 17.2 13.8 13.7 201 226 A D < - 0 0 0 -3,-2.2 26,-3.0 24,-0.2 2,-0.5 -0.484 66.0-141.5 -67.8 139.6 20.5 12.3 14.8 202 227 A I B +m 227 0E 34 -34,-2.4 -31,-0.2 24,-0.2 26,-0.1 -0.871 24.1 172.1-101.4 131.9 21.6 12.8 18.4 203 228 A G + 0 0 0 24,-2.7 -32,-2.2 -2,-0.5 -31,-1.6 0.891 9.6 174.9-101.8 -65.1 25.3 13.5 18.9 204 229 A R + 0 0 57 23,-1.4 2,-0.3 1,-0.2 25,-0.2 0.821 34.0 148.7 50.5 38.1 26.1 14.5 22.5 205 230 A C - 0 0 1 -33,-0.2 25,-2.6 -34,-0.1 2,-0.5 -0.766 43.6-138.0 -94.6 150.6 29.7 14.5 21.6 206 231 A L E -gh 174 230A 27 -33,-2.6 -31,-2.3 -2,-0.3 2,-0.6 -0.910 18.1-177.5-108.1 124.4 32.2 16.8 23.3 207 232 A V E +gh 175 231A 0 23,-2.9 25,-1.9 -2,-0.5 2,-0.3 -0.961 25.5 155.0-122.5 103.5 34.8 18.4 21.0 208 233 A D E +gh 176 232A 13 -33,-1.8 -31,-1.0 -2,-0.6 25,-0.2 -0.983 45.4 10.3-135.7 148.9 37.1 20.5 23.3 209 234 A S S S+ 0 0 24 23,-1.3 -32,-0.5 -2,-0.3 2,-0.3 0.831 78.4 146.3 60.6 37.7 40.7 21.9 23.4 210 235 A N - 0 0 0 -33,-0.2 25,-2.9 -34,-0.2 2,-0.5 -0.768 42.1-140.1 -99.6 155.1 41.6 21.2 19.8 211 236 A L E -st 179 235B 4 -33,-2.7 -31,-2.4 -2,-0.3 2,-0.6 -0.969 14.6-174.3-116.1 112.7 43.9 23.3 17.6 212 237 A F E +st 180 236B 0 23,-2.9 25,-3.4 -2,-0.5 2,-0.5 -0.966 10.6 176.8-105.1 113.1 42.8 23.7 14.0 213 238 A M E S- t 0 237B 33 -33,-2.6 25,-0.2 -2,-0.6 3,-0.2 -0.954 74.2 -16.3-127.2 112.6 45.6 25.7 12.3 214 239 A R E S+ 0 0 22 23,-2.6 2,-1.4 -2,-0.5 -32,-1.2 0.919 78.7 172.7 47.3 47.5 45.1 26.2 8.6 215 240 A Q E +s 182 0B 2 22,-0.3 -1,-0.2 -34,-0.3 3,-0.1 -0.752 16.6 150.9 -76.8 96.6 42.5 23.5 8.6 216 241 A D + 0 0 0 -34,-2.3 -31,-0.2 -2,-1.4 -1,-0.2 0.294 14.9 124.2-120.6 6.2 41.7 24.3 5.0 217 242 A S S S- 0 0 1 -35,-0.3 -32,-2.9 -33,-0.2 2,-0.2 0.771 85.4 -34.5 -42.1 -47.7 40.4 21.0 3.5 218 243 A E S S- 0 0 9 2,-0.2 -30,-0.1 -34,-0.2 -26,-0.1 -0.842 84.6 -61.4-159.9-169.0 37.0 22.5 2.4 219 244 A A S S+ 0 0 46 -32,-0.4 23,-2.2 -2,-0.2 2,-0.6 0.817 114.5 64.4 -60.0 -30.0 34.4 25.0 3.4 220 245 A E E - g 0 242C 22 21,-0.2 -28,-0.7 1,-0.2 3,-0.2 -0.841 52.8-175.1-106.4 118.6 33.6 23.3 6.7 221 246 A I E S+ 0 0 2 21,-2.8 -29,-1.5 -2,-0.6 -28,-1.3 0.945 91.4 6.2 -69.5 -47.2 36.2 23.0 9.4 222 247 A I E -fg 193 243C 0 20,-0.8 22,-2.3 -30,-0.2 2,-0.8 -1.000 68.6-157.2-132.0 132.6 33.7 20.9 11.3 223 248 A T E -fg 194 244C 2 -30,-3.0 -28,-1.6 -2,-0.4 2,-0.9 -0.875 13.7-164.5-108.6 95.9 30.4 19.8 9.9 224 249 A S E +fg 195 245C 0 20,-2.4 23,-2.0 -2,-0.8 22,-1.5 -0.750 15.6 170.3 -87.3 111.3 28.3 19.1 13.0 225 250 A K E + g 0 247C 42 -30,-2.1 -28,-0.5 -2,-0.9 -27,-0.4 -0.284 49.7 63.2-121.9 44.2 25.3 17.1 11.7 226 251 A S S > S- 0 0 0 21,-0.6 3,-0.5 -30,-0.2 -24,-0.2 -0.976 82.0 -92.5-160.5 161.3 23.6 16.0 14.9 227 252 A Q B 3 S+m 202 0E 37 -26,-3.0 -24,-2.7 -2,-0.3 -23,-1.4 -0.392 92.6 15.0 -75.2 152.9 21.9 17.5 18.0 228 253 A E T 3 S+ 0 0 27 21,-1.0 2,-0.3 22,-0.8 -1,-0.2 0.730 72.6 152.2 63.6 34.2 23.4 18.4 21.3 229 254 A N < - 0 0 0 -3,-0.5 23,-2.6 -25,-0.2 2,-0.5 -0.677 33.9-145.0 -86.8 147.2 27.2 18.4 20.5 230 255 A V E -hi 206 252A 1 -25,-2.6 -23,-2.9 -2,-0.3 2,-0.6 -0.984 11.7-167.2-121.8 126.1 29.2 20.8 22.6 231 256 A Y E +hi 207 253A 0 21,-2.7 23,-2.5 -2,-0.5 2,-0.4 -0.945 20.6 172.6-112.0 108.1 32.2 22.6 21.2 232 257 A Y E -hi 208 254A 49 -25,-1.9 -23,-1.3 -2,-0.6 23,-0.2 -0.983 54.4 -12.5-129.1 125.0 34.2 24.1 24.0 233 258 A G S S+ 0 0 14 21,-1.8 2,-0.3 -2,-0.4 23,-0.2 0.792 80.1 151.5 64.9 33.6 37.6 25.9 24.1 234 259 A N - 0 0 0 20,-0.2 23,-2.4 -25,-0.2 2,-0.4 -0.698 36.9-138.9 -92.8 149.2 38.8 25.0 20.6 235 260 A T E -tu 211 257B 2 -25,-2.9 -23,-2.9 -2,-0.3 2,-0.5 -0.949 13.2-170.7-108.9 127.2 41.2 27.3 18.7 236 261 A Y E -tu 212 258B 0 21,-3.0 23,-2.6 -2,-0.4 2,-0.5 -0.950 13.1-175.4-119.8 101.2 40.7 27.9 15.0 237 262 A L E -tu 213 259B 33 -25,-3.4 -23,-2.6 -2,-0.5 -22,-0.3 -0.917 65.0 -24.6-110.4 119.5 43.8 29.8 13.7 238 263 A N S S+ 0 0 7 21,-3.0 2,-0.6 -2,-0.5 -1,-0.2 0.889 86.1 167.7 48.8 51.0 43.9 31.0 10.1 239 264 A C - 0 0 0 29,-0.4 2,-2.1 20,-0.3 29,-1.7 -0.853 37.7-141.7 -99.2 127.7 41.4 28.4 8.9 240 265 A Q S S+ 0 0 26 -2,-0.6 2,-0.3 27,-0.2 27,-0.2 -0.463 79.7 44.9 -79.2 70.8 39.9 28.7 5.4 241 266 A G S S- 0 0 1 -2,-2.1 27,-0.4 -24,-0.1 2,-0.3 -0.972 81.1-101.7 177.0-178.0 36.4 27.5 6.5 242 267 A T E -g 220 0C 2 -23,-2.2 -21,-2.8 -2,-0.3 -20,-0.8 -0.920 26.3-117.2-128.5 156.3 33.8 27.9 9.2 243 268 A M E -gh 222 270C 0 26,-2.7 28,-1.3 -2,-0.3 2,-0.4 -0.849 48.1-153.6 -91.3 127.0 32.8 25.7 12.1 244 269 A N E -gh 223 271C 4 -22,-2.3 -20,-2.4 -2,-0.6 2,-1.1 -0.895 40.4-159.0-122.8 136.4 29.3 24.7 11.4 245 270 A F E +gh 224 272C 0 26,-1.4 28,-2.8 -2,-0.4 -20,-0.1 -0.842 40.5 162.6 -91.7 89.2 26.0 23.6 13.0 246 271 A R E + 0 0 20 -22,-1.5 64,-0.3 -2,-1.1 2,-0.3 0.904 58.6 3.0 -87.2 -46.5 25.0 22.1 9.7 247 272 A H E S+g 225 0C 8 -23,-2.0 -21,-0.6 -3,-0.2 -1,-0.3 -0.994 102.4 53.3-136.4 147.3 22.2 19.8 10.8 248 273 A G - 0 0 3 -2,-0.3 3,-0.2 -23,-0.2 -22,-0.2 0.430 66.8-117.5 104.2 122.5 20.6 19.2 14.1 249 274 A D S S+ 0 0 16 -50,-0.4 -21,-1.0 1,-0.2 27,-0.2 -0.284 83.9 41.0 -80.6 171.2 19.1 21.7 16.6 250 275 A H S S+ 0 0 28 25,-2.8 -22,-0.8 -23,-0.2 2,-0.3 0.905 72.0 156.1 57.2 53.3 20.2 22.5 20.1 251 276 A Q - 0 0 0 24,-0.3 27,-2.3 -3,-0.2 2,-0.4 -0.730 29.9-140.2-105.0 164.7 24.0 22.5 19.6 252 277 A V E +ij 230 278A 0 -23,-2.6 -21,-2.7 -2,-0.3 2,-0.4 -0.957 20.3 176.5-130.6 129.3 26.4 24.4 21.9 253 278 A A E +ij 231 279A 0 25,-2.8 27,-2.3 -2,-0.4 2,-0.4 -0.927 16.6 171.5-129.9 118.6 29.6 26.4 21.2 254 279 A I E -ij 232 280A 1 -23,-2.5 -21,-1.8 -2,-0.4 27,-0.2 -0.982 57.5 -10.5-130.2 133.1 31.3 28.1 24.1 255 280 A N S S+ 0 0 6 25,-1.9 2,-0.3 -2,-0.4 27,-0.2 0.810 79.5 151.2 54.7 40.8 34.6 29.9 24.5 256 281 A N - 0 0 1 24,-0.2 27,-2.5 -23,-0.2 2,-0.5 -0.745 39.4-133.2 -93.1 154.5 36.1 28.9 21.2 257 282 A F E -uv 235 283B 14 -23,-2.4 -21,-3.0 -2,-0.3 2,-0.6 -0.943 16.2-171.5-110.5 125.7 38.7 31.3 19.5 258 283 A Y E +uv 236 284B 0 25,-3.2 27,-2.9 -2,-0.5 2,-0.4 -0.952 19.4 173.8-120.6 104.8 38.4 32.1 15.9 259 284 A I E +uv 237 285B 20 -23,-2.6 -21,-3.0 -2,-0.6 2,-0.4 -0.950 20.6 178.8-122.2 132.4 41.6 34.0 14.9 260 285 A G E + v 0 286B 4 25,-2.8 27,-1.6 -2,-0.4 -2,-0.0 -0.998 9.1 171.7-128.2 120.8 42.8 35.2 11.5 261 286 A N + 0 0 103 -2,-0.4 2,-0.3 25,-0.1 25,-0.1 0.219 54.5 39.6-126.9 20.4 46.1 37.1 11.7 262 287 A D S S- 0 0 48 3,-0.2 3,-0.2 26,-0.1 25,-0.1 -0.884 74.8-116.2-147.1-177.5 47.3 37.7 8.2 263 288 A Q S S+ 0 0 165 -2,-0.3 3,-0.1 1,-0.1 -3,-0.0 0.136 79.1 106.3-107.3 22.4 45.9 38.6 4.8 264 289 A R S S- 0 0 135 1,-0.1 2,-0.3 24,-0.1 -1,-0.1 0.878 90.4 -9.5 -72.5 -37.4 46.8 35.4 2.9 265 290 A F S S- 0 0 53 -3,-0.2 2,-0.3 23,-0.1 -3,-0.2 -0.933 80.0 -85.4-148.2 167.9 43.2 34.0 2.7 266 291 A G - 0 0 21 -2,-0.3 2,-0.3 -3,-0.1 23,-0.3 -0.662 49.9-163.4 -78.6 139.6 39.7 34.6 4.0 267 292 A Y B -n 289 0F 0 21,-1.9 23,-0.5 -2,-0.3 2,-0.3 -0.794 10.1 -90.3-123.3 162.2 39.2 32.9 7.4 268 293 A G + 0 0 0 -29,-1.7 -29,-0.4 -27,-0.4 -9,-0.2 -0.873 30.6 158.3-136.6 171.6 36.3 31.9 9.6 269 294 A G - 0 0 0 28,-0.7 -26,-2.7 -2,-0.3 2,-0.4 0.687 54.0 -47.1 117.6 159.5 34.1 31.8 11.6 270 295 A M E -hi 243 298C 0 27,-2.4 29,-3.1 -28,-0.3 2,-0.5 -0.999 29.2-162.6-128.6 138.8 30.9 29.9 12.2 271 296 A F E -hi 244 299C 3 -28,-1.3 -26,-1.4 -2,-0.4 2,-0.5 -0.982 19.4-161.3-121.7 127.3 28.0 29.1 9.9 272 297 A V E +hi 245 300C 0 27,-2.8 29,-3.0 -2,-0.5 2,-0.3 -0.930 16.2 176.0-121.9 120.0 24.8 28.2 11.7 273 298 A W + 0 0 15 -28,-2.8 38,-0.2 -2,-0.5 39,-0.2 -0.827 52.0 21.0-108.1 154.0 21.7 26.3 10.5 274 299 A G S S- 0 0 2 36,-1.8 39,-0.7 -2,-0.3 2,-0.2 -0.110 76.0 -78.7 88.9 179.4 18.9 25.4 12.8 275 300 A S B S+o 313 0G 9 37,-0.2 -25,-2.8 1,-0.1 -24,-0.3 -0.631 84.5 41.6-125.1 172.5 17.4 26.4 16.1 276 301 A R S S+ 0 0 109 38,-2.4 39,-0.2 37,-0.8 -1,-0.1 0.585 74.0 150.8 70.3 18.4 17.7 26.3 19.9 277 302 A H - 0 0 2 36,-0.3 39,-2.3 -3,-0.2 2,-0.5 -0.236 43.0-140.4 -80.7 165.5 21.5 26.7 19.9 278 303 A V E +jk 252 316A 5 -27,-2.3 -25,-2.8 37,-0.2 2,-0.6 -0.972 22.5 174.1-124.5 113.2 23.7 28.2 22.6 279 304 A I E +jk 253 317A 0 37,-2.8 39,-2.2 -2,-0.5 2,-0.3 -0.955 23.3 152.7-123.7 99.7 26.6 30.3 21.1 280 305 A A E +jk 254 318A 0 -27,-2.3 -25,-1.9 -2,-0.6 -24,-0.2 -0.991 47.1 5.5-139.9 147.1 28.4 32.0 23.9 281 306 A C S S+ 0 0 0 37,-2.0 2,-0.3 -2,-0.3 39,-0.2 0.715 77.5 150.0 56.7 25.0 31.7 33.4 25.1 282 307 A N - 0 0 0 36,-0.3 39,-2.5 -27,-0.2 2,-0.5 -0.673 38.3-142.3 -86.8 146.5 33.3 32.9 21.7 283 308 A Y E -vw 257 321B 50 -27,-2.5 -25,-3.2 -2,-0.3 2,-0.5 -0.955 16.2-173.0-113.5 122.1 36.1 35.2 20.5 284 309 A F E +vw 258 322B 0 37,-2.7 39,-2.9 -2,-0.5 2,-0.3 -0.979 17.4 156.8-121.9 118.7 36.3 36.3 16.9 285 310 A E E +v 259 0B 56 -27,-2.9 -25,-2.8 -2,-0.5 2,-0.6 -0.841 15.7 171.9-139.5 95.4 39.2 38.3 15.5 286 311 A L E -v 260 0B 0 -2,-0.3 40,-3.2 -27,-0.2 -25,-0.1 -0.900 24.2-167.5-118.5 111.4 39.5 37.8 11.8 287 312 A S S S+ 0 0 15 -27,-1.6 2,-0.3 -2,-0.6 -1,-0.1 0.694 86.3 15.8 -68.1 -20.9 41.9 39.9 9.7 288 313 A E S S- 0 0 56 8,-0.0 -21,-1.9 -23,-0.0 2,-0.2 -0.973 75.6-155.2-149.8 140.1 40.2 38.6 6.5 289 314 A T B -n 267 0F 4 37,-0.6 2,-0.8 -2,-0.3 -21,-0.2 -0.703 34.1 -82.4-115.1 176.4 36.9 36.9 6.1 290 315 A I >>> - 0 0 23 -23,-0.5 5,-2.5 6,-0.4 3,-1.1 -0.624 28.2-162.1 -91.7 110.3 35.5 34.5 3.4 291 316 A K G >45S+ 0 0 178 -2,-0.8 3,-1.0 1,-0.2 -1,-0.2 0.894 87.5 55.7 -50.5 -48.7 34.2 36.2 0.3 292 317 A S G 345S+ 0 0 68 1,-0.3 -1,-0.2 2,-0.1 43,-0.1 0.713 110.8 44.9 -64.0 -22.8 32.1 33.2 -1.0 293 318 A R G <45S- 0 0 50 -3,-1.1 -1,-0.3 3,-0.1 -2,-0.2 0.630 129.7 -88.1 -93.9 -18.3 30.1 33.0 2.3 294 319 A G T <<5 - 0 0 21 -4,-1.0 34,-0.3 -3,-1.0 -3,-0.2 0.517 58.1 -87.5 122.7 7.7 29.5 36.7 2.6 295 320 A N S - 0 0 5 5,-0.5 3,-1.7 -2,-0.3 7,-1.2 -0.702 69.0 -99.5 -98.6 141.5 13.0 26.9 5.5 305 330 A M T 3 S- 0 0 91 44,-0.4 44,-0.1 -2,-0.3 -1,-0.1 -0.248 99.4 -7.2 -61.1 135.4 12.4 25.8 9.1 306 331 A A T 3 S+ 0 0 43 5,-0.3 -1,-0.3 1,-0.1 4,-0.1 0.703 105.0 129.0 53.7 26.1 13.8 22.3 9.9 307 332 A S S X S- 0 0 18 -3,-1.7 3,-0.8 2,-0.1 -1,-0.1 -0.229 82.5 -80.0 -95.0-169.1 14.7 21.6 6.2 308 333 A E T 3 S+ 0 0 80 1,-0.3 2,-0.3 -3,-0.1 -2,-0.1 0.744 138.9 34.7 -64.2 -25.5 17.9 20.4 4.5 309 334 A H T 3 S- 0 0 35 -5,-0.2 -5,-0.5 30,-0.1 -1,-0.3 -0.662 101.1-156.5-124.2 75.8 19.0 24.0 4.9 310 335 A A < - 0 0 6 -3,-0.8 -36,-1.8 -64,-0.3 -5,-0.2 -0.266 17.3-109.9 -69.7 132.9 17.4 24.7 8.1 311 336 A L - 0 0 1 -7,-1.2 2,-0.7 -38,-0.2 -5,-0.3 -0.198 26.2-127.6 -49.5 132.8 16.5 28.3 9.1 312 337 A A + 0 0 0 -11,-3.1 42,-0.3 -39,-0.2 2,-0.3 -0.838 56.5 126.0 -83.7 117.4 18.6 29.7 11.9 313 338 A F B +o 275 0G 22 -2,-0.7 -37,-0.8 -39,-0.7 -36,-0.3 -0.955 41.4 39.3-159.0 171.9 16.2 31.1 14.5 314 339 A D S S+ 0 0 63 40,-2.0 -38,-2.4 -2,-0.3 2,-0.3 0.924 80.8 125.4 47.4 64.9 15.3 30.9 18.2 315 340 A M E - l 0 356A 5 40,-0.6 42,-2.9 -39,-0.2 2,-0.5 -0.948 60.0-109.4-145.9 167.7 18.7 30.7 19.8 316 341 A L E -kl 278 357A 17 -39,-2.3 -37,-2.8 -2,-0.3 2,-0.5 -0.886 23.1-179.8-103.4 124.2 21.0 32.4 22.3 317 342 A I E +kl 279 358A 0 40,-3.0 42,-2.1 -2,-0.5 2,-0.4 -0.947 28.6 165.3-122.4 99.9 24.0 34.4 21.2 318 343 A A E -kl 280 359A 0 -39,-2.2 -37,-2.0 -2,-0.5 -36,-0.3 -0.967 45.7 -7.7-132.6 139.5 25.6 35.6 24.4 319 344 A N S S+ 0 0 0 40,-2.3 42,-0.2 -2,-0.4 41,-0.1 0.685 81.3 145.7 61.7 22.6 28.8 37.1 25.8 320 345 A N - 0 0 0 39,-0.3 42,-2.7 -41,-0.2 2,-0.4 -0.469 39.4-141.1 -85.7 160.5 30.7 36.7 22.5 321 346 A A E -wx 283 362B 8 -39,-2.5 -37,-2.7 40,-0.2 2,-0.6 -0.996 11.3-167.2-126.6 133.1 33.3 39.2 21.4 322 347 A F E -wx 284 363B 1 40,-2.8 42,-2.9 -2,-0.4 2,-0.5 -0.959 18.0-178.9-119.5 105.6 33.9 40.4 17.8 323 348 A I E - x 0 364B 15 -39,-2.9 42,-0.2 -2,-0.6 -37,-0.2 -0.932 62.6 -26.0-116.0 113.0 37.2 42.3 17.8 324 349 A N S S+ 0 0 9 40,-2.5 2,-0.5 -2,-0.5 -1,-0.2 0.913 77.3 179.2 50.6 46.4 38.5 43.9 14.6 325 350 A V - 0 0 10 39,-0.4 2,-1.6 -40,-0.2 -1,-0.2 -0.693 27.5-142.8 -75.5 126.2 36.7 41.5 12.3 326 351 A N S S+ 0 0 21 -40,-3.2 -37,-0.6 -2,-0.5 2,-0.3 -0.583 83.7 32.5 -87.2 73.8 37.4 42.4 8.7 327 352 A G S S- 0 0 3 -2,-1.6 -31,-0.3 44,-0.2 2,-0.2 -0.928 115.5 -43.0 161.9 178.4 33.9 41.6 7.7 328 353 A Y E -j 296 0C 41 -33,-2.6 -31,-2.2 -34,-0.3 -30,-0.2 -0.543 42.6-140.2 -66.7 143.5 30.4 41.8 9.3 329 354 A A E S+ 0 0 1 44,-1.9 -31,-2.2 1,-0.3 2,-0.4 0.941 93.5 14.9 -62.5 -49.8 30.4 40.6 12.9 330 355 A I E -jk 298 374C 0 43,-1.9 45,-1.8 -33,-0.2 2,-0.6 -0.987 66.5-162.4-133.6 126.7 27.1 38.9 12.1 331 356 A H E -jk 299 375C 10 -33,-2.8 -31,-2.7 -2,-0.4 45,-0.2 -0.953 4.1-168.7-108.9 118.2 25.5 38.3 8.7 332 357 A F S S+ 0 0 0 43,-3.1 44,-0.1 -2,-0.6 -1,-0.1 0.342 78.8 27.1 -90.6 4.4 21.8 37.6 9.1 333 358 A N S > S+ 0 0 0 42,-0.3 3,-1.1 19,-0.1 -1,-0.2 0.047 71.5 169.8-157.7 46.0 21.1 36.4 5.6 334 359 A P T 3 S+ 0 0 1 0, 0.0 -40,-0.1 0, 0.0 5,-0.1 -0.252 72.7 6.6 -64.7 149.4 24.1 34.7 3.8 335 360 A L T 3> S+ 0 0 24 -42,-0.1 4,-2.1 1,-0.1 5,-0.2 0.763 80.0 153.9 54.0 33.9 23.5 32.9 0.6 336 361 A D H <> + 0 0 15 -3,-1.1 4,-2.3 1,-0.2 5,-0.2 0.859 65.0 55.4 -66.0 -34.4 19.9 34.0 0.5 337 362 A E H > S+ 0 0 131 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.941 110.6 45.7 -63.1 -43.9 19.5 33.8 -3.3 338 363 A R H > S+ 0 0 132 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.885 112.4 52.3 -63.9 -39.7 20.6 30.1 -3.3 339 364 A R H X S+ 0 0 11 -4,-2.1 4,-2.5 2,-0.2 -1,-0.2 0.867 105.4 52.7 -67.1 -36.2 18.3 29.4 -0.4 340 365 A K H X S+ 0 0 85 -4,-2.3 4,-2.9 2,-0.2 -1,-0.2 0.889 108.8 52.5 -64.0 -38.4 15.3 30.9 -2.2 341 366 A E H X S+ 0 0 148 -4,-1.8 4,-2.3 2,-0.2 -2,-0.2 0.920 110.3 47.3 -57.7 -47.1 16.1 28.6 -5.1 342 367 A Y H X S+ 0 0 55 -4,-2.0 4,-1.8 2,-0.2 -2,-0.2 0.917 114.0 47.0 -59.5 -46.7 16.1 25.6 -2.7 343 368 A C H X>S+ 0 0 2 -4,-2.5 5,-3.2 1,-0.2 4,-0.7 0.930 112.3 49.6 -69.2 -39.4 12.9 26.6 -1.1 344 369 A A H ><5S+ 0 0 79 -4,-2.9 3,-0.9 1,-0.2 -1,-0.2 0.936 109.8 51.2 -63.7 -44.0 11.1 27.3 -4.4 345 370 A A H 3<5S+ 0 0 83 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.878 117.7 38.1 -58.4 -40.8 12.2 23.9 -5.9 346 371 A N H 3<5S- 0 0 90 -4,-1.8 -1,-0.2 -5,-0.2 -2,-0.2 0.381 110.5-117.2 -95.8 2.7 10.9 22.0 -2.9 347 372 A R T <<5 + 0 0 237 -3,-0.9 2,-0.3 -4,-0.7 -3,-0.2 0.900 65.2 148.6 58.1 47.1 7.8 24.1 -2.3 348 373 A L < - 0 0 69 -5,-3.2 2,-0.7 -6,-0.2 -1,-0.2 -0.716 53.9-103.4-106.9 160.5 9.1 25.2 1.1 349 374 A K - 0 0 147 -2,-0.3 -44,-0.4 -44,-0.1 2,-0.3 -0.747 30.9-142.6 -85.5 114.2 8.6 28.5 2.9 350 375 A F + 0 0 50 -2,-0.7 2,-0.3 -46,-0.1 -46,-0.2 -0.591 29.6 167.8 -76.6 133.7 11.6 30.8 2.8 351 376 A E B -P 303 0H 32 -48,-1.4 -48,-2.1 -2,-0.3 3,-0.0 -0.868 26.6-130.7-139.1 166.5 12.2 32.7 6.1 352 377 A T - 0 0 21 -2,-0.3 -19,-0.1 -50,-0.2 -51,-0.1 -0.888 45.3 -72.2-123.9 154.4 15.0 34.8 7.6 353 378 A P + 0 0 0 0, 0.0 2,-0.3 0, 0.0 -40,-0.2 -0.097 64.2 150.8 -50.5 133.7 16.6 34.5 11.1 354 379 A H + 0 0 44 -42,-0.3 -40,-2.0 1,-0.1 30,-0.2 -0.929 42.5 50.9-155.5 174.0 14.4 35.8 13.9 355 380 A Q S S+ 0 0 97 28,-2.9 -40,-0.6 -2,-0.3 2,-0.3 0.790 70.7 157.1 55.1 31.6 13.8 35.2 17.6 356 381 A L E -l 315 0A 0 -42,-0.2 29,-2.7 27,-0.2 2,-0.7 -0.678 36.5-147.2 -84.3 138.7 17.5 35.6 18.2 357 382 A M E -lm 316 385A 68 -42,-2.9 -40,-3.0 -2,-0.3 2,-0.8 -0.927 15.3-172.6-108.7 103.2 18.4 36.5 21.8 358 383 A L E +lm 317 386A 0 27,-3.1 29,-2.5 -2,-0.7 2,-0.4 -0.899 16.3 170.5-101.6 105.2 21.6 38.7 21.4 359 384 A K E -lm 318 387A 58 -42,-2.1 -40,-2.3 -2,-0.8 -39,-0.3 -0.975 53.5 -14.2-127.2 123.4 22.8 39.3 25.0 360 385 A G S S+ 0 0 0 27,-2.3 2,-0.2 -2,-0.4 29,-0.2 0.719 81.3 154.2 72.0 24.4 26.0 40.7 26.4 361 386 A N - 0 0 0 26,-0.3 29,-2.3 -42,-0.2 2,-0.5 -0.616 36.1-140.1 -88.3 147.7 28.0 40.7 23.2 362 387 A L E -xy 321 390B 11 -42,-2.7 -40,-2.8 -2,-0.2 2,-0.5 -0.935 15.6-174.5-108.8 128.4 30.9 43.0 22.5 363 388 A F E +xy 322 391B 0 27,-2.8 29,-2.4 -2,-0.5 2,-0.4 -0.990 19.1 163.6-123.6 113.3 31.3 44.4 19.0 364 389 A F E +xy 323 392B 24 -42,-2.9 -40,-2.5 -2,-0.5 -39,-0.4 -0.998 15.4 171.6-140.8 136.3 34.5 46.5 18.6 365 390 A K + 0 0 21 27,-1.8 -42,-0.0 -2,-0.4 -2,-0.0 -0.985 16.4 155.4-142.4 132.8 36.6 47.8 15.8 366 391 A D + 0 0 114 -2,-0.3 -1,-0.1 28,-0.0 27,-0.1 0.178 58.6 87.7-133.1 15.0 39.6 50.2 15.8 367 392 A K S S- 0 0 90 -42,-0.1 2,-0.7 2,-0.0 -43,-0.1 -0.828 90.3-106.2-108.2 152.9 41.3 49.1 12.6 368 393 A P + 0 0 124 0, 0.0 -42,-0.0 0, 0.0 -3,-0.0 0.046 65.1 142.1 -76.9 32.6 40.3 50.7 9.3 369 394 A Y - 0 0 47 -2,-0.7 -44,-0.1 1,-0.1 -43,-0.1 -0.323 50.0-133.1 -67.5 158.4 38.3 47.7 7.8 370 395 A V + 0 0 120 24,-0.0 -1,-0.1 2,-0.0 -44,-0.1 0.461 64.8 104.7-100.1 -3.3 35.2 48.9 5.9 371 396 A Y - 0 0 53 -46,-0.2 -44,-0.2 -44,-0.1 -46,-0.1 -0.637 62.7-132.4 -89.2 135.1 32.4 46.7 7.1 372 397 A P - 0 0 22 0, 0.0 24,-0.2 0, 0.0 -43,-0.2 -0.271 36.5-103.3 -68.8 167.6 29.7 47.7 9.5 373 398 A F S S+ 0 0 11 22,-1.8 -43,-1.9 -45,-0.2 -44,-1.9 0.839 96.2 35.3 -67.9 -31.2 29.1 45.3 12.2 374 399 A F E -k 330 0C 2 22,-2.4 2,-0.5 21,-0.2 -43,-0.2 -0.929 52.2-164.4-129.7 149.5 25.9 43.8 10.8 375 400 A K E +k 331 0C 57 -45,-1.8 -43,-3.1 -2,-0.4 2,-0.3 -0.973 23.8 154.0-126.0 115.5 24.3 42.8 7.5 376 401 A D > + 0 0 14 -2,-0.5 3,-1.1 21,-0.4 -2,-0.0 -0.779 13.4 176.5-141.4 95.3 20.5 42.2 7.6 377 402 A D T 3 S+ 0 0 92 -2,-0.3 -1,-0.1 1,-0.3 -44,-0.0 0.533 86.4 48.9 -74.5 -5.9 18.8 42.8 4.3 378 403 A Y T 3 S+ 0 0 60 -25,-0.1 -1,-0.3 -3,-0.1 -26,-0.1 -0.102 79.1 163.1-122.6 35.4 15.5 41.6 5.8 379 404 A F < - 0 0 63 -3,-1.1 2,-0.4 1,-0.0 -3,-0.0 -0.283 11.9-179.0 -61.4 132.6 15.6 43.7 9.0 380 405 A I > - 0 0 108 0, 0.0 3,-1.9 0, 0.0 4,-0.3 -0.993 34.5-108.3-132.9 126.3 12.2 43.9 10.8 381 406 A A T 3 S+ 0 0 85 -2,-0.4 19,-0.1 1,-0.2 -2,-0.0 -0.290 100.9 8.4 -52.1 128.9 11.8 45.9 14.0 382 407 A G T 3 S+ 0 0 76 2,-0.2 -1,-0.2 1,-0.1 -27,-0.1 0.329 89.6 116.2 86.7 -7.2 11.3 43.7 17.1 383 408 A K S < S+ 0 0 31 -3,-1.9 -28,-2.9 -29,-0.1 2,-0.3 0.815 81.8 32.1 -70.2 -28.7 12.1 40.3 15.3 384 409 A N S S- 0 0 18 -4,-0.3 2,-0.5 -30,-0.2 -2,-0.2 -0.815 80.6-128.1-118.6 164.6 15.2 39.8 17.5 385 410 A S E -m 357 0A 45 -29,-2.7 -27,-3.1 -2,-0.3 2,-0.5 -0.958 20.0-171.2-118.2 123.7 15.9 40.8 21.1 386 411 A W E +m 358 0A 47 -2,-0.5 2,-0.4 -29,-0.2 -27,-0.2 -0.970 13.2 163.8-117.4 122.7 19.1 42.8 21.9 387 412 A T E -m 359 0A 78 -29,-2.5 -27,-2.3 -2,-0.5 -26,-0.3 -0.995 60.4 -3.7-140.7 130.2 20.1 43.3 25.6 388 413 A G S S+ 0 0 47 -2,-0.4 22,-0.3 -29,-0.2 -29,-0.1 0.589 84.2 141.8 76.0 13.7 23.4 44.4 27.2 389 414 A N - 0 0 7 -31,-0.2 14,-0.6 -29,-0.2 2,-0.4 -0.344 38.4-148.7 -80.2 162.3 25.5 44.4 24.1 390 415 A V E -yz 362 403B 5 -29,-2.3 -27,-2.8 12,-0.1 2,-0.4 -0.998 14.9-179.0-130.9 136.4 28.2 47.1 23.4 391 416 A A E +y 363 0B 2 12,-2.7 2,-0.3 -2,-0.4 -27,-0.2 -0.972 12.4 151.2-138.3 122.2 29.0 48.3 19.9 392 417 A L E +y 364 0B 48 -29,-2.4 -27,-1.8 -2,-0.4 3,-0.1 -0.974 42.7 46.6-155.4 140.9 31.7 50.8 19.0 393 418 A G S S+ 0 0 49 -2,-0.3 2,-0.3 -29,-0.2 -29,-0.1 0.141 104.4 26.0 125.0 -19.3 34.0 51.6 16.2 394 419 A V S S- 0 0 34 -28,-0.0 -21,-0.1 -24,-0.0 -1,-0.1 -0.960 95.5 -74.0-162.3 157.3 31.9 51.6 13.0 395 420 A E - 0 0 141 -2,-0.3 -22,-1.8 1,-0.1 -21,-0.2 -0.203 39.7-127.3 -54.2 153.7 28.2 52.0 12.1 396 421 A K - 0 0 58 -24,-0.2 -22,-2.4 2,-0.2 -1,-0.1 0.862 24.9-140.4 -76.9 -33.9 26.0 49.1 13.1 397 422 A G S S+ 0 0 45 1,-0.2 -21,-0.4 -24,-0.2 -1,-0.1 0.338 77.6 65.0 86.9 -6.7 24.5 48.7 9.6 398 423 A I S S- 0 0 16 2,-0.2 2,-1.9 -23,-0.1 -1,-0.2 -0.941 96.6-100.5-137.3 157.7 21.0 48.0 11.0 399 424 A P S S+ 0 0 98 0, 0.0 2,-0.4 0, 0.0 0, 0.0 -0.541 72.6 128.1 -81.6 75.6 18.6 50.2 13.0 400 425 A V - 0 0 21 -2,-1.9 2,-0.7 -19,-0.1 -2,-0.2 -1.000 56.5-131.6-130.2 135.0 19.3 48.8 16.5 401 426 A N + 0 0 161 -2,-0.4 2,-0.4 -15,-0.1 -15,-0.1 -0.758 34.6 171.1 -83.8 117.3 20.1 51.0 19.4 402 427 A I - 0 0 12 -2,-0.7 -12,-0.1 -11,-0.1 -11,-0.1 -0.982 38.1-105.4-130.0 138.4 23.2 49.5 21.3 403 428 A S B -z 390 0B 59 -14,-0.6 -12,-2.7 -2,-0.4 6,-0.0 -0.250 21.0-161.2 -55.2 145.9 25.2 51.1 24.0 404 429 A A + 0 0 63 -14,-0.2 2,-1.2 -12,-0.0 -1,-0.1 0.214 54.7 117.2-113.5 16.0 28.6 52.4 22.9 405 430 A N + 0 0 83 1,-0.2 3,-0.5 2,-0.1 4,-0.2 -0.685 35.7 176.0 -91.5 91.7 30.0 52.5 26.4 406 431 A R S > S+ 0 0 112 -2,-1.2 3,-1.7 1,-0.2 -1,-0.2 0.868 77.5 60.3 -65.8 -36.0 32.9 50.0 26.4 407 432 A S T 3 S+ 0 0 118 1,-0.3 -1,-0.2 3,-0.0 -2,-0.1 0.796 105.7 49.2 -61.4 -30.1 33.9 50.8 30.0 408 433 A A T 3 S+ 0 0 41 -3,-0.5 -1,-0.3 2,-0.0 2,-0.2 0.441 84.7 124.8 -87.8 -1.9 30.5 49.6 31.1 409 434 A Y < + 0 0 47 -3,-1.7 -20,-0.1 -4,-0.2 -47,-0.1 -0.422 28.7 157.7 -64.1 127.1 30.7 46.4 29.1 410 435 A K - 0 0 147 -22,-0.3 -91,-0.1 -2,-0.2 24,-0.1 -0.978 43.5-109.6-143.3 139.0 30.2 43.2 31.2 411 436 A P - 0 0 44 0, 0.0 2,-0.2 0, 0.0 -51,-0.1 -0.308 42.7-112.4 -57.3 150.9 29.1 39.7 30.2 412 437 A V - 0 0 48 -53,-0.2 2,-0.4 -52,-0.1 22,-0.2 -0.591 21.2-117.1 -89.6 146.2 25.6 38.8 31.3 413 438 A K - 0 0 130 -2,-0.2 2,-0.4 20,-0.1 16,-0.1 -0.710 32.2-168.6 -77.7 136.2 24.9 36.2 34.0 414 439 A I + 0 0 6 14,-0.4 18,-0.3 -2,-0.4 17,-0.1 -0.987 20.9 160.5-131.9 134.5 22.8 33.3 32.6 415 440 A K + 0 0 157 -2,-0.4 13,-0.1 16,-0.1 -1,-0.1 0.424 59.9 72.8-134.6 0.2 21.1 30.7 34.7 416 441 A D + 0 0 116 12,-0.1 2,-0.5 2,-0.1 -2,-0.0 0.397 63.1 117.5-103.2 4.3 18.4 29.0 32.7 417 442 A I - 0 0 20 1,-0.0 11,-0.4 -139,-0.0 10,-0.1 -0.608 59.3-136.9 -82.4 123.1 20.6 27.0 30.3 418 443 A Q - 0 0 143 -2,-0.5 2,-0.1 9,-0.1 -2,-0.1 -0.502 21.6-123.0 -75.2 139.8 20.1 23.2 30.6 419 444 A P - 0 0 71 0, 0.0 2,-0.6 0, 0.0 7,-0.1 -0.331 29.9 -99.1 -70.8 169.9 23.3 21.2 30.5 420 445 A I > - 0 0 4 5,-0.3 3,-2.4 3,-0.3 5,-0.3 -0.801 39.9-113.9 -93.1 121.9 23.8 18.5 27.9 421 446 A E T 3 S+ 0 0 109 -2,-0.6 3,-0.1 1,-0.3 -1,-0.0 -0.247 101.5 18.5 -50.0 130.6 23.1 15.0 29.3 422 447 A G T 3 S+ 0 0 55 1,-0.1 2,-0.6 -250,-0.0 -1,-0.3 0.375 103.1 98.5 86.3 -4.8 26.3 13.0 29.3 423 448 A I < - 0 0 14 -3,-2.4 2,-2.3 2,-0.1 -3,-0.3 -0.941 67.2-145.0-119.3 116.0 28.6 16.0 29.1 424 449 A A + 0 0 108 -2,-0.6 2,-0.4 -5,-0.1 -3,-0.1 -0.350 57.9 116.7 -81.6 57.6 30.1 17.1 32.4 425 450 A L - 0 0 39 -2,-2.3 2,-1.1 -5,-0.3 -5,-0.3 -0.998 61.6-137.3-123.1 138.8 30.1 20.9 31.8 426 451 A D > - 0 0 96 -2,-0.4 4,-2.4 1,-0.2 5,-0.2 -0.775 20.8-172.8 -91.3 95.5 28.1 23.5 33.6 427 452 A L H > S+ 0 0 3 -2,-1.1 4,-2.7 1,-0.2 5,-0.3 0.881 80.5 52.2 -64.9 -40.5 26.9 25.6 30.8 428 453 A N H > S+ 0 0 34 -11,-0.4 4,-2.4 1,-0.2 -14,-0.4 0.928 112.1 47.1 -58.2 -43.9 25.4 28.4 32.9 429 454 A A H > S+ 0 0 39 1,-0.2 4,-1.2 2,-0.2 -2,-0.2 0.928 113.8 46.1 -65.7 -45.4 28.6 28.7 34.9 430 455 A L H < S+ 0 0 22 -4,-2.4 4,-0.5 1,-0.2 3,-0.2 0.895 114.7 47.3 -67.3 -39.2 30.9 28.8 31.8 431 456 A I H >< S+ 0 0 0 -4,-2.7 3,-1.4 -5,-0.2 -1,-0.2 0.927 110.2 53.0 -66.8 -40.3 28.7 31.3 30.0 432 457 A S H 3< S+ 0 0 17 -4,-2.4 -1,-0.2 -5,-0.3 -2,-0.2 0.716 100.0 62.5 -72.0 -20.0 28.4 33.6 33.1 433 458 A K T 3< S- 0 0 135 -4,-1.2 -1,-0.3 1,-0.3 -2,-0.2 0.662 98.9-142.5 -72.3 -20.2 32.2 33.7 33.4 434 459 A G < - 0 0 4 -3,-1.4 2,-0.6 -4,-0.5 -1,-0.3 -0.509 53.8 -16.9 84.2-160.3 32.6 35.4 30.0 435 460 A I S S- 0 0 56 -2,-0.2 2,-0.3 -116,-0.1 -153,-0.1 -0.707 72.0-172.0 -84.1 118.5 35.5 34.6 27.7 436 461 A T - 0 0 55 -2,-0.6 -2,-0.1 -155,-0.2 -203,-0.0 -0.741 41.3 -1.4-108.6 157.1 38.3 32.8 29.6 437 462 A G S S- 0 0 73 -2,-0.3 3,-0.0 2,-0.0 -182,-0.0 -0.195 74.8 -99.1 74.2-157.9 41.8 31.9 28.6 438 463 A K - 0 0 155 -205,-0.1 -181,-0.1 -181,-0.0 -2,-0.0 -0.928 51.8 -48.0-155.9 173.6 43.4 32.5 25.2 439 464 A P - 0 0 54 0, 0.0 2,-0.2 0, 0.0 -228,-0.1 -0.201 61.4-114.7 -52.9 139.1 44.2 30.6 21.9 440 465 A L - 0 0 32 -230,-0.2 2,-0.2 -183,-0.1 -230,-0.0 -0.551 25.4-146.0 -76.3 146.5 45.8 27.2 22.3 441 466 A S >> - 0 0 55 -2,-0.2 3,-1.1 1,-0.1 4,-0.6 -0.589 29.7-103.5-105.9 162.7 49.4 26.5 21.1 442 467 A W H >> S+ 0 0 27 1,-0.2 4,-2.3 -2,-0.2 3,-1.4 0.885 119.7 59.4 -49.0 -44.0 50.9 23.3 19.7 443 468 A D H 34 S+ 0 0 111 1,-0.3 -1,-0.2 2,-0.2 -3,-0.0 0.770 100.8 57.0 -64.1 -20.1 52.6 22.6 23.0 444 469 A E H <4 S+ 0 0 99 -3,-1.1 -1,-0.3 1,-0.1 -2,-0.2 0.669 120.5 24.6 -86.1 -13.4 49.3 22.5 24.7 445 470 A V H << S+ 0 0 2 -3,-1.4 -2,-0.2 -4,-0.6 -1,-0.1 0.572 91.3 120.5-119.8 -16.7 47.8 19.8 22.5 446 471 A R S < S- 0 0 58 -4,-2.3 -306,-0.1 -5,-0.2 5,-0.1 -0.029 75.0 -90.0 -58.3 151.6 50.8 17.8 21.1 447 472 A P > - 0 0 1 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 -0.331 42.5-117.8 -51.1 141.3 51.4 14.0 21.7 448 473 A Y T 3 S+ 0 0 122 1,-0.3 -2,-0.1 -3,-0.1 -309,-0.0 0.846 112.4 45.5 -57.9 -29.8 53.4 13.7 24.9 449 474 A W T 3 S+ 0 0 46 1,-0.1 2,-0.6 -342,-0.1 -1,-0.3 0.442 98.9 79.8 -92.5 -3.1 56.3 12.1 23.1 450 475 A L < + 0 0 15 -3,-1.9 -1,-0.1 1,-0.2 -396,-0.0 -0.891 41.5 168.2-117.2 109.2 56.5 14.5 20.1 451 476 A K + 0 0 174 -2,-0.6 2,-0.5 1,-0.1 -1,-0.2 0.918 62.2 69.0 -86.7 -40.4 58.1 17.9 20.3 452 477 A E S S- 0 0 163 1,-0.1 -1,-0.1 -6,-0.0 0, 0.0 -0.660 84.6-122.0 -86.0 126.9 58.3 18.9 16.7 453 478 A M - 0 0 47 -2,-0.5 -1,-0.1 1,-0.1 -2,-0.1 -0.421 32.2-139.0 -59.7 124.8 55.0 19.7 14.8 454 479 A P + 0 0 12 0, 0.0 4,-0.2 0, 0.0 -310,-0.1 -0.271 54.9 57.1 -80.0 173.6 54.7 17.4 11.8 455 480 A G - 0 0 32 -312,-0.1 4,-0.1 1,-0.1 -273,-0.1 0.078 66.6-119.4 93.9 164.5 53.5 18.4 8.3 456 481 A T S S+ 0 0 38 2,-0.1 6,-0.5 8,-0.1 4,-0.2 0.541 98.8 59.3-112.1 -17.7 54.5 20.9 5.7 457 482 A Y S >> S+ 0 0 12 -276,-0.2 4,-2.9 4,-0.1 3,-0.8 0.801 84.9 70.5 -89.4 -33.4 51.3 23.0 5.5 458 483 A A T 34 S+ 0 0 3 1,-0.3 -1,-0.1 -277,-0.2 -2,-0.1 0.881 109.6 31.4 -60.5 -45.4 50.7 24.4 8.9 459 484 A L T 34 S+ 0 0 132 -4,-0.1 -1,-0.3 1,-0.1 -2,-0.1 0.533 133.1 29.4 -85.0 -7.3 53.5 26.9 9.0 460 485 A T T <4 S- 0 0 43 -3,-0.8 -2,-0.2 -4,-0.2 -3,-0.1 0.578 85.8-129.6-130.4 -21.1 53.7 27.7 5.2 461 486 A A S < S+ 0 0 13 -4,-2.9 2,-0.3 1,-0.1 -4,-0.1 0.697 82.6 90.3 62.7 24.4 50.2 27.3 3.6 462 487 A R S S- 0 0 146 -6,-0.5 -1,-0.1 -5,-0.2 2,-0.1 -0.983 75.7-124.9-148.3 135.3 51.9 25.1 1.0 463 488 A L - 0 0 24 -2,-0.3 -6,-0.0 1,-0.1 -8,-0.0 -0.495 39.1-102.5 -71.1 149.1 52.6 21.5 0.6 464 489 A S > - 0 0 37 -2,-0.1 4,-2.9 1,-0.1 5,-0.2 -0.166 42.7 -97.7 -61.6 162.2 56.2 20.4 0.1 465 490 A A H > S+ 0 0 87 1,-0.2 4,-2.0 2,-0.2 5,-0.1 0.912 121.7 46.7 -56.2 -47.1 57.0 19.5 -3.6 466 491 A D H > S+ 0 0 109 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.909 115.8 44.7 -63.2 -43.9 56.7 15.7 -3.2 467 492 A R H > S+ 0 0 43 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.846 110.1 56.1 -68.0 -38.1 53.4 15.9 -1.3 468 493 A A H X S+ 0 0 19 -4,-2.9 4,-2.3 2,-0.2 -1,-0.2 0.885 105.4 52.6 -58.2 -39.7 52.1 18.5 -3.7 469 494 A A H X S+ 0 0 62 -4,-2.0 4,-2.0 -5,-0.2 -2,-0.2 0.938 110.4 46.6 -65.0 -43.3 52.7 16.0 -6.6 470 495 A K H X S+ 0 0 72 -4,-1.8 4,-2.4 1,-0.2 -2,-0.2 0.907 110.6 53.0 -62.5 -42.7 50.7 13.3 -4.8 471 496 A F H X S+ 0 0 23 -4,-2.4 4,-2.6 1,-0.2 5,-0.2 0.925 107.0 52.2 -58.7 -45.1 47.9 15.7 -4.1 472 497 A K H X S+ 0 0 142 -4,-2.3 4,-2.5 1,-0.2 -1,-0.2 0.912 108.6 51.2 -59.0 -41.3 47.7 16.7 -7.8 473 498 A A H X S+ 0 0 35 -4,-2.0 4,-2.1 1,-0.2 -2,-0.2 0.916 110.3 48.5 -65.1 -39.3 47.4 13.0 -8.7 474 499 A V H X S+ 0 0 2 -4,-2.4 4,-1.0 2,-0.2 -2,-0.2 0.934 112.4 47.9 -62.6 -47.1 44.6 12.5 -6.2 475 500 A I H >< S+ 0 0 45 -4,-2.6 3,-0.6 1,-0.2 4,-0.5 0.936 111.3 52.0 -63.4 -40.8 42.7 15.5 -7.4 476 501 A K H >< S+ 0 0 163 -4,-2.5 3,-1.2 1,-0.2 -1,-0.2 0.922 108.8 48.1 -61.9 -44.1 43.1 14.5 -11.1 477 502 A R H 3< S+ 0 0 115 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.683 108.6 56.3 -75.7 -9.2 41.8 10.9 -10.7 478 503 A N T << S+ 0 0 83 -4,-1.0 -1,-0.3 -3,-0.6 -2,-0.2 0.507 101.4 66.1 -98.7 -6.7 38.8 12.1 -8.8 479 504 A K S < S- 0 0 149 -3,-1.2 -3,-0.0 -4,-0.5 0, 0.0 -0.543 100.8 -56.0-112.0-179.8 37.5 14.5 -11.4 480 505 A E 0 0 169 -2,-0.2 -1,-0.2 1,-0.1 -2,-0.1 -0.146 360.0 360.0 -56.0 143.9 36.1 14.1 -15.0 481 506 A H 0 0 238 -3,-0.1 -1,-0.1 -4,-0.1 -2,-0.0 0.854 360.0 360.0 -67.9 360.0 38.4 12.3 -17.4