==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 08-JAN-07 2OGT . COMPND 2 MOLECULE: THERMOSTABLE CARBOXYLESTERASE EST50; . SOURCE 2 ORGANISM_SCIENTIFIC: GEOBACILLUS STEAROTHERMOPHILUS; . AUTHOR P.LIU,H.E.EWIS,P.C.TAI,C.D.LU,I.T.WEBER . 463 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18677.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 306 66.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 43 9.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 26 5.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 5.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 64 13.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 125 27.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 1 3 2 1 1 0 1 1 1 0 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 2 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A R 0 0 244 0, 0.0 78,-0.4 0, 0.0 13,-0.1 0.000 360.0 360.0 360.0 -14.1 -1.0 -4.3 44.1 2 4 A T + 0 0 37 11,-0.1 11,-2.4 76,-0.1 2,-0.5 0.654 360.0 81.1 -93.3 -12.9 -0.5 -4.4 40.3 3 5 A V E +A 12 0A 32 9,-0.2 2,-0.4 76,-0.1 9,-0.2 -0.828 56.3 178.6-101.5 126.1 -2.9 -1.6 39.4 4 6 A V E -A 11 0A 4 7,-2.3 7,-2.2 -2,-0.5 2,-0.4 -0.952 22.6-132.3-123.5 143.2 -1.7 1.9 39.7 5 7 A E E +A 10 0A 119 -2,-0.4 5,-0.2 5,-0.2 2,-0.2 -0.805 26.7 178.7 -99.1 139.4 -3.5 5.1 38.9 6 8 A T E > -A 9 0A 18 3,-1.7 3,-1.3 -2,-0.4 156,-0.1 -0.700 48.7 -92.0-121.3 179.0 -1.8 7.8 36.9 7 9 A R T 3 S+ 0 0 175 1,-0.3 3,-0.1 -2,-0.2 38,-0.1 0.797 129.3 45.5 -64.0 -21.5 -2.9 11.2 35.5 8 10 A Y T 3 S- 0 0 38 1,-0.4 38,-2.5 37,-0.1 -1,-0.3 0.486 126.7 -76.7 -98.4 -3.8 -3.9 9.4 32.4 9 11 A G E < -A 6 0A 18 -3,-1.3 -3,-1.7 36,-0.2 -1,-0.4 -0.735 63.1 -44.5 132.0 173.6 -5.7 6.4 33.9 10 12 A R E -Ab 5 49A 119 38,-0.8 40,-2.6 -5,-0.2 2,-0.4 -0.534 45.5-160.9 -82.9 145.1 -5.0 3.1 35.6 11 13 A L E -Ab 4 50A 0 -7,-2.2 -7,-2.3 38,-0.2 2,-0.6 -0.988 9.0-143.7-128.9 138.7 -2.3 0.7 34.5 12 14 A R E +Ab 3 51A 89 38,-2.5 40,-2.4 -2,-0.4 -9,-0.2 -0.906 25.6 171.1-105.9 118.9 -2.0 -3.1 35.3 13 15 A G - 0 0 3 -11,-2.4 2,-0.3 -2,-0.6 9,-0.2 -0.179 23.5-115.7-103.0-159.8 1.5 -4.5 35.7 14 16 A E E -C 21 0B 78 7,-2.5 7,-2.9 38,-0.2 2,-0.3 -0.942 17.0-110.6-139.4 159.6 2.9 -7.8 36.9 15 17 A M E +C 20 0B 123 -2,-0.3 2,-0.3 5,-0.2 5,-0.3 -0.711 38.9 174.5 -84.7 138.0 4.9 -9.3 39.8 16 18 A N E > -C 19 0B 61 3,-4.0 3,-1.9 -2,-0.3 -2,-0.0 -0.885 64.5 -18.5-151.9 118.6 8.3 -10.6 38.6 17 19 A E T 3 S- 0 0 105 -2,-0.3 3,-0.1 1,-0.3 -2,-0.0 0.840 127.4 -52.6 51.7 37.2 11.2 -12.0 40.8 18 20 A G T 3 S+ 0 0 51 1,-0.3 2,-0.3 94,-0.0 -1,-0.3 0.588 124.9 92.6 77.3 5.8 9.5 -10.3 43.9 19 21 A V E < S-C 16 0B 2 -3,-1.9 -3,-4.0 59,-0.0 2,-0.3 -0.818 75.0-114.7-122.6 169.0 9.4 -6.9 42.2 20 22 A F E -CD 15 76B 28 56,-3.1 56,-2.5 -2,-0.3 2,-0.4 -0.823 27.2-169.0-103.8 142.4 6.6 -5.2 40.2 21 23 A V E -CD 14 75B 1 -7,-2.9 -7,-2.5 -2,-0.3 2,-0.4 -1.000 11.8-168.9-135.3 137.2 7.0 -4.2 36.5 22 24 A W E - D 0 74B 0 52,-2.6 52,-2.6 -2,-0.4 2,-0.3 -0.996 19.3-166.9-119.5 123.8 4.8 -2.1 34.2 23 25 A K E + 0 0 37 29,-2.8 31,-0.4 -2,-0.4 50,-0.2 -0.866 55.3 14.7-118.1 146.5 5.7 -2.3 30.5 24 26 A G E + 0 0 6 -2,-0.3 -1,-0.2 1,-0.2 49,-0.2 0.902 67.5 172.3 66.3 45.4 4.8 -0.3 27.4 25 27 A I E - D 0 72B 0 47,-3.4 47,-2.0 -3,-0.2 2,-0.4 -0.759 32.3-128.6 -85.9 127.1 3.4 2.8 29.1 26 28 A P E + D 0 71B 16 0, 0.0 45,-0.2 0, 0.0 3,-0.1 -0.636 28.6 177.3 -75.1 125.3 2.7 5.5 26.5 27 29 A Y + 0 0 4 43,-1.5 2,-0.3 -2,-0.4 44,-0.1 0.472 66.9 19.4-105.3 -4.1 4.4 8.8 27.7 28 30 A A S S- 0 0 6 42,-0.7 -1,-0.1 14,-0.2 42,-0.1 -0.967 93.4 -82.5-153.8 159.6 3.4 10.8 24.6 29 31 A K - 0 0 63 12,-2.7 12,-0.4 -2,-0.3 -2,-0.0 -0.465 63.7 -91.8 -65.7 139.7 0.9 10.8 21.7 30 32 A A - 0 0 23 1,-0.1 2,-1.9 -2,-0.1 38,-0.2 -0.389 32.8-134.5 -57.8 126.3 2.2 8.5 18.9 31 33 A P + 0 0 5 0, 0.0 6,-0.3 0, 0.0 2,-0.2 -0.383 62.2 124.0 -84.4 62.8 4.2 10.7 16.5 32 34 A V > - 0 0 58 -2,-1.9 3,-2.4 4,-0.1 4,-0.1 -0.707 61.3 -2.6-116.9 163.8 2.6 9.2 13.4 33 35 A G G > S+ 0 0 47 1,-0.3 3,-1.4 -2,-0.2 0, 0.0 -0.341 138.6 3.2 58.2-125.7 0.7 10.7 10.4 34 36 A E G 3 S+ 0 0 170 1,-0.2 -1,-0.3 -2,-0.1 206,-0.0 0.539 131.8 61.5 -69.2 -5.3 0.3 14.4 10.9 35 37 A R G X S+ 0 0 89 -3,-2.4 3,-1.7 -5,-0.1 -1,-0.2 0.416 74.5 121.8 -98.5 -1.0 2.4 14.3 14.1 36 38 A R T < S+ 0 0 10 -3,-1.4 -4,-0.1 1,-0.3 92,-0.0 -0.449 82.4 10.1 -62.1 139.0 5.5 12.9 12.3 37 39 A F T 3 S+ 0 0 3 91,-0.3 -1,-0.3 -6,-0.3 106,-0.2 0.567 105.9 116.1 61.0 17.6 8.5 15.3 12.8 38 40 A L S < S- 0 0 49 -3,-1.7 -1,-0.2 1,-0.1 3,-0.1 -0.832 75.9 -92.8-110.4 152.8 6.7 17.3 15.5 39 41 A P - 0 0 32 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.225 56.7 -86.3 -56.7 155.5 7.6 17.6 19.2 40 42 A P - 0 0 22 0, 0.0 -10,-0.1 0, 0.0 -12,-0.0 -0.348 42.9-155.9 -69.0 140.9 6.0 15.0 21.4 41 43 A E - 0 0 101 -12,-0.4 -12,-2.7 -3,-0.1 -3,-0.0 -0.811 33.5 -81.4-112.9 156.1 2.6 15.9 22.8 42 44 A P - 0 0 85 0, 0.0 -14,-0.2 0, 0.0 -1,-0.1 -0.233 54.0-102.7 -54.4 149.1 1.0 14.5 26.1 43 45 A P - 0 0 11 0, 0.0 2,-0.2 0, 0.0 -14,-0.1 -0.277 36.6-101.2 -71.6 154.8 -0.6 11.1 25.8 44 46 A D - 0 0 113 -16,-0.1 2,-0.1 1,-0.1 -36,-0.1 -0.538 36.1-121.6 -73.0 143.7 -4.4 10.7 25.6 45 47 A A - 0 0 72 -2,-0.2 2,-0.3 -38,-0.1 -36,-0.2 -0.393 27.9-156.6 -76.6 160.0 -6.1 9.6 28.8 46 48 A W - 0 0 43 -38,-2.5 2,-0.2 -2,-0.1 -36,-0.2 -0.948 12.3-127.3-135.0 161.4 -8.2 6.4 28.9 47 49 A D S S+ 0 0 169 -2,-0.3 -39,-0.0 -38,-0.1 -38,-0.0 -0.653 74.3 21.5 -99.0 163.5 -11.0 5.0 30.9 48 50 A G S S- 0 0 54 -2,-0.2 -38,-0.8 1,-0.1 2,-0.7 -0.163 107.4 -45.3 72.2-170.9 -10.7 1.5 32.6 49 51 A V E -b 10 0A 43 -40,-0.1 2,-0.4 -38,-0.1 -38,-0.2 -0.865 54.3-148.0-103.0 114.0 -7.6 -0.4 33.4 50 52 A R E -b 11 0A 89 -40,-2.6 -38,-2.5 -2,-0.7 2,-0.1 -0.632 20.0-118.3 -85.2 129.2 -4.9 -0.4 30.7 51 53 A E E +b 12 0A 108 -2,-0.4 -38,-0.1 -40,-0.2 3,-0.1 -0.379 31.4 175.7 -65.6 139.3 -2.7 -3.5 30.4 52 54 A A + 0 0 2 -40,-2.4 -29,-2.8 -31,-0.1 -38,-0.2 -0.342 48.1 104.6-137.3 52.2 1.0 -2.8 30.9 53 55 A T S S+ 0 0 34 -31,-0.2 2,-0.3 -40,-0.1 -29,-0.1 0.433 71.1 57.6-117.7 1.7 2.3 -6.3 30.8 54 56 A S S S- 0 0 90 -31,-0.4 -1,-0.1 -3,-0.1 -31,-0.0 -0.977 86.7-110.6-125.8 140.4 3.9 -6.3 27.2 55 57 A F - 0 0 75 -2,-0.3 3,-0.1 1,-0.1 -2,-0.1 -0.368 34.0-120.7 -62.0 150.7 6.6 -4.0 25.9 56 58 A G - 0 0 17 1,-0.2 -32,-0.1 16,-0.1 13,-0.1 -0.324 44.3 -73.9 -79.6 173.5 5.5 -1.5 23.3 57 59 A P - 0 0 55 0, 0.0 14,-0.2 0, 0.0 -1,-0.2 -0.286 48.5-114.5 -61.3 152.4 7.1 -1.5 19.8 58 60 A V - 0 0 30 1,-0.1 8,-2.9 -3,-0.1 3,-0.1 -0.541 40.6 -93.2 -80.9 160.3 10.6 -0.1 19.5 59 61 A V B -m 66 0C 4 39,-0.3 8,-0.2 10,-0.3 39,-0.2 -0.217 61.2 -68.1 -69.6 162.6 11.0 3.1 17.4 60 62 A M S S+ 0 0 13 6,-0.5 65,-0.3 5,-0.2 68,-0.2 -0.249 75.5 141.5 -54.0 132.3 11.8 2.8 13.7 61 63 A Q - 0 0 9 -3,-0.1 36,-0.1 1,-0.1 187,-0.1 -0.944 67.8 -90.7-168.5 162.6 15.3 1.4 13.2 62 64 A P 0 0 60 0, 0.0 -1,-0.1 0, 0.0 35,-0.1 0.823 360.0 360.0 -53.2 -38.1 17.3 -1.0 11.0 63 65 A S 0 0 101 -3,-0.1 -3,-0.1 35,-0.0 34,-0.0 0.828 360.0 360.0 -34.4 360.0 16.4 -3.7 13.4 64 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 65 80 A P 0 0 88 0, 0.0 2,-0.3 0, 0.0 -6,-0.2 0.000 360.0 360.0 360.0 155.6 9.6 -1.6 14.9 66 81 A S B -m 59 0C 39 -8,-2.9 -6,-0.5 1,-0.1 0, 0.0 -0.987 360.0-122.0-149.4 152.2 7.1 1.3 14.5 67 82 A E S S+ 0 0 32 -2,-0.3 2,-1.6 -8,-0.2 3,-0.2 0.766 108.9 74.8 -63.7 -24.3 6.9 5.1 14.4 68 83 A D + 0 0 55 1,-0.2 -1,-0.2 -38,-0.2 -38,-0.1 -0.640 64.3 115.5 -84.2 82.0 4.4 4.4 17.3 69 84 A G + 0 0 0 -2,-1.6 2,-1.6 -13,-0.1 -10,-0.3 0.245 19.1 126.4-139.6 19.2 7.2 3.6 19.8 70 85 A L + 0 0 2 -3,-0.2 -43,-1.5 -42,-0.1 -42,-0.7 -0.609 42.2 133.4 -88.7 86.4 7.1 6.3 22.6 71 86 A Y E -D 26 0B 25 -2,-1.6 51,-2.0 -45,-0.2 2,-0.3 -0.893 37.0-160.1-129.9 155.0 6.8 4.0 25.6 72 87 A L E -DE 25 121B 0 -47,-2.0 -47,-3.4 -2,-0.3 2,-0.3 -0.908 7.9-145.3-137.0 163.4 8.5 3.6 29.0 73 88 A N E - E 0 120B 2 47,-2.4 47,-2.2 -2,-0.3 2,-0.4 -0.955 8.7-156.8-134.3 142.6 8.8 0.8 31.5 74 89 A I E -DE 22 119B 0 -52,-2.6 -52,-2.6 -2,-0.3 2,-0.4 -0.995 7.8-170.9-130.8 129.5 8.9 0.8 35.3 75 90 A W E +DE 21 118B 4 43,-2.4 43,-2.3 -2,-0.4 -54,-0.2 -0.972 19.7 163.7-113.3 135.4 10.3 -1.6 37.9 76 91 A S E -D 20 0B 0 -56,-2.5 -56,-3.1 -2,-0.4 3,-0.2 -0.989 45.2-133.3-149.6 141.5 9.5 -1.0 41.6 77 92 A P S S- 0 0 29 0, 0.0 2,-0.2 0, 0.0 90,-0.1 0.785 95.7 -10.5 -58.6 -29.0 9.6 -3.0 44.8 78 93 A A - 0 0 27 88,-0.4 2,-1.6 -58,-0.1 4,-0.2 -0.841 60.0-123.2-173.5 132.9 6.1 -1.7 45.5 79 94 A A S S+ 0 0 36 -78,-0.4 2,-0.2 -2,-0.2 88,-0.2 -0.669 72.2 113.4 -79.6 85.5 3.6 0.8 44.3 80 95 A D S S- 0 0 51 -2,-1.6 87,-0.6 84,-0.1 3,-0.2 -0.641 82.0 -88.3-133.0-162.5 3.2 2.6 47.6 81 96 A G S S+ 0 0 62 -2,-0.2 84,-0.1 1,-0.2 -2,-0.1 -0.108 78.6 120.8-103.8 43.9 4.0 6.1 48.8 82 97 A K - 0 0 153 -4,-0.2 -1,-0.2 82,-0.1 87,-0.1 0.407 66.6-131.1 -97.0 12.1 7.6 5.5 50.1 83 98 A K - 0 0 149 85,-0.4 85,-0.2 -3,-0.2 86,-0.2 0.896 35.1-179.1 50.5 54.3 9.7 7.9 48.0 84 99 A R E -f 168 0B 18 83,-1.9 85,-2.9 1,-0.1 88,-0.2 -0.489 38.1 -88.7 -76.1 154.1 12.4 5.7 46.7 85 100 A P E - 0 0 13 0, 0.0 32,-2.7 0, 0.0 2,-0.5 -0.311 43.0-139.0 -57.2 148.3 15.3 6.9 44.5 86 101 A V E -fg 173 117B 0 86,-2.5 88,-3.0 83,-0.3 2,-0.6 -0.987 9.5-158.5-118.9 122.5 14.4 6.8 40.8 87 102 A L E -fg 174 118B 0 30,-2.8 32,-2.9 -2,-0.5 2,-0.6 -0.927 8.2-165.3-101.3 117.1 16.9 5.7 38.2 88 103 A F E -fg 175 119B 0 86,-3.0 88,-2.6 -2,-0.6 2,-0.4 -0.931 10.0-158.0-108.6 107.5 15.9 7.0 34.7 89 104 A W E -fg 176 120B 0 30,-3.1 32,-1.1 -2,-0.6 2,-0.6 -0.750 12.7-167.5 -97.7 131.4 17.9 5.1 32.0 90 105 A I E -f 177 0B 0 86,-2.6 88,-0.7 -2,-0.4 95,-0.1 -0.951 23.9-137.4-114.8 111.8 18.5 6.4 28.4 91 106 A H - 0 0 1 -2,-0.6 93,-0.1 30,-0.5 9,-0.1 -0.237 9.9-135.5 -70.2 163.8 19.9 3.7 26.2 92 107 A G + 0 0 4 88,-0.2 87,-0.1 89,-0.1 -1,-0.1 -0.040 43.7 137.2 -99.4-162.2 22.7 4.1 23.6 93 108 A G S >> S- 0 0 9 85,-0.1 4,-2.3 5,-0.1 3,-2.2 0.644 84.3 -82.6 120.9 23.1 23.0 2.9 20.1 94 109 A A T 34 S- 0 0 33 1,-0.3 166,-0.6 2,-0.2 32,-0.1 0.709 77.4 -71.6 59.0 26.0 24.5 5.9 18.2 95 110 A F T 34 S+ 0 0 0 2,-0.3 31,-3.3 1,-0.1 -1,-0.3 0.758 130.5 83.9 60.6 24.7 21.1 7.6 17.9 96 111 A L T <4 S+ 0 0 39 -3,-2.2 2,-0.3 1,-0.4 -2,-0.2 0.713 91.6 6.9-119.2 -51.3 20.4 4.9 15.3 97 112 A F S < S+ 0 0 102 -4,-2.3 -1,-0.4 -36,-0.1 -2,-0.3 -0.840 75.7 72.4-135.7 172.7 19.2 1.8 17.1 98 113 A G - 0 0 13 -2,-0.3 -39,-0.3 -39,-0.2 2,-0.3 -0.551 41.8-136.7 118.8-179.1 18.1 0.3 20.5 99 114 A S > - 0 0 3 -2,-0.2 3,-1.2 -41,-0.1 23,-0.2 -0.947 27.5-116.6-171.9 155.8 15.3 0.4 23.0 100 115 A G T 3 S+ 0 0 0 -2,-0.3 22,-0.1 1,-0.2 5,-0.1 0.617 110.4 67.2 -73.2 -11.7 14.5 0.6 26.7 101 116 A S T 3 + 0 0 24 -45,-0.1 -1,-0.2 5,-0.1 -46,-0.1 0.434 68.8 124.1 -90.8 1.1 12.9 -2.8 26.4 102 117 A S X - 0 0 31 -3,-1.2 3,-2.1 1,-0.1 4,-0.1 -0.409 69.9-128.6 -56.5 136.1 16.2 -4.6 25.7 103 118 A P G > S+ 0 0 61 0, 0.0 3,-1.8 0, 0.0 -1,-0.1 0.780 105.4 73.2 -61.0 -25.6 16.8 -7.4 28.2 104 119 A W G 3 S+ 0 0 94 1,-0.3 283,-0.1 289,-0.2 285,-0.1 0.699 100.3 43.4 -54.6 -28.2 20.2 -5.8 28.8 105 120 A Y G < S+ 0 0 8 -3,-2.1 -1,-0.3 -6,-0.1 -16,-0.1 0.160 77.4 148.5-107.1 14.3 18.5 -2.9 30.7 106 121 A D < - 0 0 33 -3,-1.8 3,-0.4 1,-0.2 4,-0.3 -0.240 38.9-150.4 -52.9 127.7 16.0 -5.0 32.7 107 122 A G > + 0 0 0 1,-0.2 4,-2.6 2,-0.1 5,-0.2 0.420 68.7 100.1 -88.6 5.2 15.5 -3.1 36.0 108 123 A T H > S+ 0 0 2 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.929 81.8 48.4 -59.0 -50.9 14.8 -6.1 38.2 109 124 A A H > S+ 0 0 7 -3,-0.4 4,-2.8 1,-0.2 5,-0.3 0.930 113.2 47.0 -62.6 -46.8 18.3 -6.3 39.8 110 125 A F H > S+ 0 0 0 -4,-0.3 4,-2.0 277,-0.3 6,-0.4 0.955 114.4 47.5 -53.1 -50.4 18.5 -2.6 40.6 111 126 A A H X>S+ 0 0 1 -4,-2.6 4,-1.1 1,-0.2 5,-0.5 0.898 117.2 42.0 -62.9 -41.7 15.0 -2.5 42.1 112 127 A K H <5S+ 0 0 95 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.909 120.9 38.6 -69.0 -48.7 15.6 -5.6 44.2 113 128 A H H <5S+ 0 0 77 -4,-2.8 -2,-0.2 -5,-0.2 -1,-0.2 0.635 128.0 30.6 -81.7 -19.6 19.2 -4.9 45.4 114 129 A G H <5S- 0 0 5 -4,-2.0 -3,-0.2 -5,-0.3 -1,-0.2 0.567 94.5-124.0-119.4 -9.3 18.8 -1.1 45.9 115 130 A D T <5 + 0 0 88 -4,-1.1 2,-0.3 -5,-0.4 -4,-0.2 0.985 69.3 131.1 55.2 56.8 15.1 -0.6 46.9 116 131 A V < - 0 0 0 -5,-0.5 2,-0.4 -6,-0.4 -1,-0.2 -0.875 61.2-115.7-132.7 164.4 14.8 1.8 44.0 117 132 A V E - g 0 86B 0 -32,-2.7 -30,-2.8 -2,-0.3 2,-0.4 -0.885 28.7-158.3-100.8 135.5 12.5 2.5 41.1 118 133 A V E -Eg 75 87B 0 -43,-2.3 -43,-2.4 -2,-0.4 2,-0.4 -0.960 7.1-170.5-118.4 136.5 13.9 2.0 37.6 119 134 A V E -Eg 74 88B 0 -32,-2.9 -30,-3.1 -2,-0.4 2,-0.4 -0.994 1.6-174.1-123.9 132.0 12.5 3.6 34.4 120 135 A T E -Eg 73 89B 0 -47,-2.2 -47,-2.4 -2,-0.4 2,-0.3 -0.947 13.2-166.7-123.1 148.0 13.7 2.7 30.9 121 136 A I E -E 72 0B 0 -32,-1.1 -30,-0.5 -2,-0.4 2,-0.3 -0.885 22.3-137.6-130.0 160.1 12.5 4.6 27.8 122 137 A N - 0 0 4 -51,-2.0 2,-0.3 -2,-0.3 -23,-0.1 -0.810 25.7-179.9-101.7 154.6 12.3 4.6 24.0 123 138 A Y - 0 0 0 -2,-0.3 -64,-0.2 -53,-0.1 25,-0.1 -0.966 38.7 -85.3-147.8 152.4 12.9 7.9 22.1 124 139 A R - 0 0 9 -2,-0.3 2,-0.2 23,-0.2 27,-0.1 -0.345 52.7-175.3 -64.9 143.2 12.8 8.7 18.4 125 140 A M >> + 0 0 1 -65,-0.3 3,-1.8 -29,-0.1 4,-1.2 -0.726 37.6 2.4-130.0 176.1 16.1 7.9 16.6 126 141 A N H >> S- 0 0 0 -31,-3.3 4,-2.4 1,-0.3 3,-0.7 -0.083 127.1 -6.1 43.8-131.4 17.8 8.2 13.2 127 142 A V H 34 S+ 0 0 0 1,-0.2 -1,-0.3 2,-0.2 4,-0.3 0.650 138.3 51.7 -74.1 -10.8 15.7 10.0 10.5 128 143 A F H <4 S+ 0 0 10 -3,-1.8 -91,-0.3 -68,-0.2 -1,-0.2 0.774 122.8 26.3 -91.8 -24.0 12.6 10.2 12.7 129 144 A G H << S+ 0 0 0 -4,-1.2 19,-1.9 -3,-0.7 18,-0.6 0.568 130.9 31.6-112.2 -19.4 14.3 11.8 15.7 130 145 A F < + 0 0 1 -4,-2.4 2,-1.1 -5,-0.2 131,-0.2 -0.082 69.8 133.2-139.1 36.7 17.3 13.7 14.3 131 146 A L - 0 0 1 13,-0.8 2,-0.7 -4,-0.3 15,-0.2 -0.754 47.3-148.2 -89.8 103.1 16.4 14.9 10.8 132 147 A H + 0 0 9 -2,-1.1 90,-0.1 13,-0.2 10,-0.1 -0.604 28.0 166.2 -76.3 115.4 17.5 18.5 10.8 133 148 A L > - 0 0 0 -2,-0.7 3,-2.4 8,-0.5 4,-0.3 0.505 18.4-166.1-104.5 -6.7 15.2 20.4 8.5 134 149 A G T 3 - 0 0 6 1,-0.3 3,-0.3 8,-0.2 -1,-0.3 -0.341 68.4 -40.8 55.5-140.0 16.1 24.0 9.5 135 150 A D T > S+ 0 0 102 1,-0.2 3,-1.2 2,-0.1 -1,-0.3 0.081 110.7 111.3 -96.6 17.9 13.3 26.3 8.0 136 151 A S T < S+ 0 0 50 -3,-2.4 -1,-0.2 1,-0.3 -2,-0.1 0.771 87.8 30.9 -71.3 -19.9 13.3 24.3 4.8 137 152 A F T 3 S- 0 0 6 1,-0.4 -1,-0.3 -3,-0.3 3,-0.2 0.154 127.7 -86.0-116.7 16.3 9.8 22.9 5.5 138 153 A G X - 0 0 23 -3,-1.2 3,-1.3 -5,-0.2 -1,-0.4 -0.217 53.9 -64.0 101.9 167.4 8.5 25.9 7.5 139 154 A E G > S+ 0 0 139 1,-0.3 3,-1.8 2,-0.2 4,-0.2 0.789 121.3 71.4 -63.4 -32.8 8.6 26.9 11.2 140 155 A A G 3 S+ 0 0 52 1,-0.3 3,-0.3 -3,-0.2 -1,-0.3 0.778 103.5 42.2 -53.7 -28.2 6.6 23.9 12.4 141 156 A Y G X S+ 0 0 15 -3,-1.3 3,-1.9 1,-0.2 -8,-0.5 0.285 79.1 109.9-103.7 12.0 9.6 21.6 11.6 142 157 A A T < S+ 0 0 3 -3,-1.8 3,-0.3 1,-0.3 -8,-0.2 0.692 79.9 48.3 -63.7 -16.6 12.3 23.9 13.0 143 158 A Q T > S+ 0 0 70 -3,-0.3 3,-2.5 -106,-0.2 -1,-0.3 0.379 78.0 108.9 -97.6 1.0 12.9 21.5 16.0 144 159 A A G X + 0 0 1 -3,-1.9 3,-1.1 1,-0.3 -13,-0.8 0.735 65.8 65.7 -59.0 -25.6 13.1 18.3 13.9 145 160 A G G 3 S+ 0 0 0 -3,-0.3 -1,-0.3 1,-0.2 -13,-0.2 0.632 111.8 34.2 -71.8 -12.4 16.9 17.9 14.4 146 161 A N G X> S+ 0 0 0 -3,-2.5 4,-2.0 -15,-0.2 3,-0.5 0.003 74.9 121.4-130.0 25.0 16.5 17.3 18.1 147 162 A L H <> S+ 0 0 0 -3,-1.1 4,-2.2 -18,-0.6 -23,-0.2 0.880 73.2 58.5 -61.1 -35.3 13.2 15.5 18.4 148 163 A G H 3> S+ 0 0 0 -19,-1.9 4,-1.7 1,-0.2 -1,-0.2 0.880 107.4 49.5 -63.2 -33.0 14.7 12.4 20.1 149 164 A I H <> S+ 0 0 0 -3,-0.5 4,-2.2 -20,-0.3 -1,-0.2 0.914 109.5 50.5 -70.0 -41.5 16.0 14.8 22.9 150 165 A L H X S+ 0 0 22 -4,-2.0 4,-2.4 1,-0.2 -2,-0.2 0.865 107.2 55.2 -64.0 -32.6 12.5 16.3 23.2 151 166 A D H X S+ 0 0 0 -4,-2.2 4,-2.5 2,-0.2 5,-0.2 0.932 107.1 49.9 -62.0 -46.3 11.1 12.8 23.5 152 167 A Q H X S+ 0 0 0 -4,-1.7 4,-2.2 1,-0.2 -2,-0.2 0.941 110.8 48.8 -61.4 -44.1 13.5 12.1 26.4 153 168 A V H X S+ 0 0 6 -4,-2.2 4,-2.5 1,-0.2 -1,-0.2 0.907 109.5 53.4 -61.4 -41.2 12.4 15.4 28.1 154 169 A A H X S+ 0 0 19 -4,-2.4 4,-2.1 2,-0.2 -2,-0.2 0.912 109.7 47.5 -59.4 -43.9 8.7 14.4 27.6 155 170 A A H X S+ 0 0 0 -4,-2.5 4,-2.5 2,-0.2 -1,-0.2 0.904 110.8 51.7 -64.7 -40.9 9.4 11.0 29.3 156 171 A L H X S+ 0 0 0 -4,-2.2 4,-2.6 -5,-0.2 -2,-0.2 0.889 109.0 50.5 -65.4 -39.0 11.2 12.7 32.2 157 172 A R H X S+ 0 0 121 -4,-2.5 4,-2.2 2,-0.2 -2,-0.2 0.896 108.9 52.2 -62.8 -38.7 8.2 15.1 32.6 158 173 A W H X S+ 0 0 4 -4,-2.1 4,-2.5 2,-0.2 5,-0.3 0.934 111.2 47.5 -59.7 -47.5 5.8 12.0 32.7 159 174 A V H X S+ 0 0 0 -4,-2.5 4,-2.8 1,-0.2 5,-0.3 0.950 110.1 50.3 -63.1 -45.6 8.0 10.5 35.4 160 175 A K H < S+ 0 0 59 -4,-2.6 4,-0.2 1,-0.2 -1,-0.2 0.928 116.8 43.6 -57.7 -37.0 8.1 13.7 37.5 161 176 A E H < S+ 0 0 87 -4,-2.2 -2,-0.2 -5,-0.2 -1,-0.2 0.810 130.7 18.2 -77.9 -30.4 4.3 13.9 37.3 162 177 A N H >< S+ 0 0 6 -4,-2.5 3,-1.3 -5,-0.1 4,-0.3 0.581 91.5 92.5-121.5 -13.0 3.5 10.2 37.9 163 178 A I G ><>S+ 0 0 0 -4,-2.8 5,-2.0 -5,-0.3 3,-1.7 0.735 74.0 73.3 -68.6 -22.3 6.3 8.2 39.5 164 179 A A G > 5S+ 0 0 54 -5,-0.3 3,-1.5 1,-0.3 -1,-0.3 0.866 91.7 59.0 -54.4 -34.4 5.1 8.7 43.1 165 180 A A G < 5S+ 0 0 40 -3,-1.3 -1,-0.3 1,-0.3 -2,-0.2 0.721 104.1 51.5 -67.9 -21.0 2.2 6.3 42.3 166 181 A F G < 5S- 0 0 0 -3,-1.7 -88,-0.4 -4,-0.3 -1,-0.3 0.233 129.7 -92.1 -99.5 9.5 4.8 3.6 41.5 167 182 A G T < 5S+ 0 0 0 -3,-1.5 -83,-1.9 -87,-0.6 2,-0.2 0.640 85.7 126.9 94.4 11.6 6.8 4.1 44.7 168 183 A G E < -f 84 0B 2 -5,-2.0 -85,-0.4 -85,-0.2 -1,-0.3 -0.669 60.3-123.0-108.5 160.2 9.3 6.6 43.5 169 184 A D E > - 0 0 32 -85,-2.9 3,-2.1 3,-0.2 -83,-0.3 -0.889 12.6-160.3 -99.1 110.9 10.4 10.1 44.7 170 185 A P E 3 S+ 0 0 29 0, 0.0 3,-0.4 0, 0.0 -1,-0.1 0.700 94.6 55.7 -65.1 -14.8 9.9 12.6 41.9 171 186 A D E 3 S+ 0 0 102 1,-0.2 27,-0.1 27,-0.1 -11,-0.0 0.370 103.7 55.5 -97.4 4.3 12.4 14.8 43.7 172 187 A N E < S+ 0 0 13 -3,-2.1 -86,-2.5 -88,-0.2 2,-0.5 -0.376 72.0 144.2-128.8 55.1 15.1 12.1 43.7 173 188 A I E -f 86 0B 0 -3,-0.4 26,-3.0 -88,-0.2 27,-1.6 -0.797 28.3-166.7 -95.2 132.0 15.5 11.2 40.0 174 189 A T E -fh 87 200B 0 -88,-3.0 -86,-3.0 -2,-0.5 2,-0.4 -0.975 9.0-153.1-111.8 122.7 18.9 10.3 38.7 175 190 A I E +fh 88 201B 0 25,-2.1 27,-2.3 -2,-0.5 2,-0.3 -0.735 22.8 168.5 -91.2 142.2 19.2 10.2 34.9 176 191 A F E +fh 89 202B 0 -88,-2.6 -86,-2.6 -2,-0.4 2,-0.3 -0.985 6.5 159.7-150.2 160.0 21.9 7.9 33.4 177 192 A G E -fh 90 203B 0 25,-1.1 27,-2.6 -2,-0.3 2,-0.3 -0.954 27.8-124.7-170.4 164.8 22.9 6.5 30.1 178 193 A E E > S- h 0 204B 19 -88,-0.7 3,-2.9 -2,-0.3 27,-0.2 -0.930 71.1 -26.4-122.2 147.3 25.8 5.0 28.1 179 194 A S T >> S+ 0 0 4 25,-2.3 4,-2.4 -2,-0.3 3,-1.0 -0.309 142.4 7.2 54.2-124.0 27.3 6.1 24.8 180 195 A A H 3> S+ 0 0 0 1,-0.3 4,-2.2 2,-0.2 -1,-0.3 0.799 134.0 58.3 -57.5 -26.0 24.6 8.0 22.9 181 196 A G H <> S+ 0 0 0 -3,-2.9 4,-2.1 2,-0.2 -1,-0.3 0.845 106.6 46.3 -69.9 -33.9 22.6 7.7 26.1 182 197 A A H <> S+ 0 0 0 -3,-1.0 4,-2.6 22,-0.3 -2,-0.2 0.863 109.1 54.4 -77.1 -33.8 25.3 9.5 28.0 183 198 A A H X S+ 0 0 1 -4,-2.4 4,-2.6 2,-0.2 -2,-0.2 0.923 108.3 51.2 -62.9 -40.2 25.5 12.1 25.3 184 199 A S H X S+ 0 0 0 -4,-2.2 4,-2.7 -5,-0.2 5,-0.2 0.943 108.4 49.5 -59.3 -46.1 21.8 12.5 25.8 185 200 A V H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 -1,-0.2 0.924 109.5 53.3 -59.0 -39.6 22.3 13.0 29.6 186 201 A G H X S+ 0 0 5 -4,-2.6 4,-0.8 1,-0.2 -2,-0.2 0.914 110.5 46.7 -64.2 -40.4 25.0 15.6 28.7 187 202 A V H >X S+ 0 0 1 -4,-2.6 3,-1.0 1,-0.2 4,-0.8 0.935 111.5 50.8 -62.3 -45.2 22.5 17.5 26.6 188 203 A L H >< S+ 0 0 2 -4,-2.7 3,-0.7 1,-0.3 6,-0.2 0.875 103.2 59.1 -66.3 -35.6 19.8 17.3 29.2 189 204 A L H 3< S+ 0 0 7 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.850 110.4 44.2 -57.6 -31.7 22.1 18.6 31.8 190 205 A S H << S+ 0 0 13 -3,-1.0 -1,-0.2 -4,-0.8 -2,-0.2 0.585 91.3 104.3 -87.6 -17.3 22.6 21.8 29.6 191 206 A L XX - 0 0 4 -4,-0.8 3,-1.6 -3,-0.7 4,-0.6 -0.640 57.3-154.8 -88.3 118.4 18.9 22.3 28.7 192 207 A P G >4 S+ 0 0 90 0, 0.0 3,-1.3 0, 0.0 -1,-0.2 0.854 96.1 55.7 -51.7 -41.3 16.9 25.0 30.4 193 208 A E G 34 S+ 0 0 74 1,-0.3 -5,-0.1 75,-0.2 -2,-0.0 0.588 108.3 48.4 -80.3 -6.7 13.6 23.2 29.8 194 209 A A G X4 S+ 0 0 0 -3,-1.6 3,-2.0 -6,-0.2 4,-0.4 0.471 81.7 120.9 -99.2 -3.8 14.9 20.1 31.6 195 210 A S T << S+ 0 0 92 -3,-1.3 87,-0.1 -4,-0.6 -6,-0.1 -0.410 79.4 17.5 -67.2 134.0 16.3 22.0 34.7 196 211 A G T 3 S+ 0 0 52 2,-0.4 -1,-0.3 -2,-0.1 3,-0.1 0.278 97.8 100.2 87.0 -8.7 14.6 20.8 37.9 197 212 A L S < S+ 0 0 17 -3,-2.0 2,-0.3 1,-0.1 -2,-0.1 0.695 89.5 24.5 -80.4 -16.5 13.3 17.6 36.4 198 213 A F - 0 0 16 -4,-0.4 -2,-0.4 1,-0.1 -24,-0.2 -0.968 59.5-151.0-145.6 160.1 16.2 15.5 37.8 199 214 A R S S+ 0 0 121 -26,-3.0 2,-0.3 -2,-0.3 -25,-0.2 0.765 77.3 10.5-103.4 -33.6 18.5 15.7 40.8 200 215 A R E -h 174 0B 12 -27,-1.6 -25,-2.1 85,-0.2 2,-0.3 -0.916 61.6-149.5-142.4 166.5 21.7 13.9 39.7 201 216 A A E -hi 175 287B 0 85,-1.8 87,-1.9 -2,-0.3 2,-0.4 -0.997 2.9-160.4-144.2 148.5 23.2 12.4 36.5 202 217 A M E -hi 176 288B 0 -27,-2.3 -25,-1.1 -2,-0.3 2,-0.5 -0.998 7.0-164.9-129.9 132.7 25.5 9.6 35.5 203 218 A L E -hi 177 289B 2 85,-2.6 87,-2.1 -2,-0.4 2,-0.7 -0.945 2.3-166.3-123.4 108.4 27.4 9.5 32.2 204 219 A Q E S-hi 178 290B 0 -27,-2.6 -25,-2.3 -2,-0.5 -22,-0.3 -0.852 72.4 -26.5-101.9 109.6 28.9 6.1 31.1 205 220 A S S S+ 0 0 0 85,-2.4 2,-0.3 -2,-0.7 -1,-0.2 0.909 122.6 68.0 55.5 46.1 31.4 6.4 28.2 206 221 A G - 0 0 8 84,-0.5 2,-0.3 -3,-0.2 84,-0.2 -0.926 52.0-171.7-177.8 168.1 29.9 9.5 26.7 207 222 A S > - 0 0 2 -2,-0.3 3,-1.9 139,-0.2 144,-0.1 -0.899 51.9 -75.9-154.7 174.0 29.4 13.2 27.2 208 223 A G T 3 S+ 0 0 1 -2,-0.3 66,-0.1 1,-0.3 -25,-0.1 0.603 124.0 60.3 -55.8 -18.5 27.6 16.2 25.6 209 224 A S T > S+ 0 0 28 64,-0.1 3,-1.5 138,-0.1 2,-0.3 0.682 78.1 107.9 -80.5 -19.7 30.2 16.3 22.8 210 225 A L T < S- 0 0 8 -3,-1.9 136,-0.0 1,-0.3 137,-0.0 -0.421 98.0 -11.2 -70.9 124.1 29.6 12.8 21.5 211 226 A L T 3 S+ 0 0 29 -2,-0.3 -1,-0.3 1,-0.2 2,-0.2 0.608 93.1 155.1 69.3 13.7 27.7 12.7 18.1 212 227 A L < - 0 0 38 -3,-1.5 2,-0.3 49,-0.1 -1,-0.2 -0.589 25.5-157.9 -74.8 138.2 26.9 16.4 18.4 213 228 A R B -n 263 0D 16 49,-2.7 51,-2.3 -2,-0.2 -1,-0.0 -0.863 14.2-131.5-118.4 147.5 26.4 18.2 15.0 214 229 A S > - 0 0 44 -2,-0.3 4,-2.9 49,-0.2 5,-0.2 -0.583 33.2-113.2 -83.2 160.2 26.5 21.8 13.8 215 230 A P H > S+ 0 0 36 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.867 118.1 53.1 -61.8 -37.7 23.6 23.0 11.8 216 231 A E H > S+ 0 0 147 2,-0.2 4,-1.8 1,-0.2 5,-0.1 0.919 112.3 44.1 -63.6 -46.5 25.7 23.3 8.7 217 232 A T H > S+ 0 0 68 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.918 115.2 48.0 -61.7 -49.8 26.9 19.7 9.0 218 233 A A H X S+ 0 0 0 -4,-2.9 4,-2.5 1,-0.2 -86,-0.2 0.895 109.1 53.0 -63.8 -39.7 23.3 18.4 9.8 219 234 A M H X S+ 0 0 53 -4,-2.7 4,-2.3 -5,-0.2 -1,-0.2 0.921 106.3 53.1 -63.8 -40.6 21.7 20.2 6.9 220 235 A A H X S+ 0 0 52 -4,-1.8 4,-1.4 1,-0.2 -1,-0.2 0.916 110.0 48.4 -60.0 -42.6 24.2 18.7 4.4 221 236 A M H X S+ 0 0 27 -4,-1.7 4,-2.3 1,-0.2 3,-0.3 0.916 109.5 53.0 -61.5 -45.3 23.3 15.2 5.7 222 237 A T H X S+ 0 0 1 -4,-2.5 4,-3.0 1,-0.2 5,-0.2 0.887 104.1 56.1 -58.3 -37.7 19.6 16.0 5.4 223 238 A E H X S+ 0 0 129 -4,-2.3 4,-1.8 1,-0.2 -1,-0.2 0.889 108.9 46.9 -62.5 -38.2 20.0 17.1 1.8 224 239 A R H X S+ 0 0 113 -4,-1.4 4,-1.9 -3,-0.3 -2,-0.2 0.921 113.1 48.3 -70.5 -42.0 21.5 13.7 1.0 225 240 A I H X S+ 0 0 4 -4,-2.3 4,-1.9 1,-0.2 -2,-0.2 0.908 110.6 50.1 -63.0 -45.6 18.8 11.8 2.8 226 241 A L H X>S+ 0 0 7 -4,-3.0 5,-2.5 1,-0.2 4,-0.8 0.890 108.2 54.6 -64.3 -33.7 16.0 13.7 1.2 227 242 A D H ><5S+ 0 0 127 -4,-1.8 3,-0.9 -5,-0.2 -1,-0.2 0.936 110.7 45.0 -60.6 -45.9 17.6 13.0 -2.2 228 243 A K H 3<5S+ 0 0 105 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.792 112.4 52.5 -66.8 -29.1 17.6 9.3 -1.5 229 244 A A H 3<5S- 0 0 16 -4,-1.9 -1,-0.3 2,-0.1 -2,-0.2 0.542 110.2-121.1 -84.9 -10.5 14.0 9.4 -0.2 230 245 A G T <<5 + 0 0 53 -3,-0.9 2,-0.5 -4,-0.8 -3,-0.2 0.855 65.8 139.9 72.2 32.6 12.8 11.2 -3.3 231 246 A I < - 0 0 6 -5,-2.5 -1,-0.2 -6,-0.2 -2,-0.1 -0.944 46.2-141.7-111.3 120.6 11.5 14.2 -1.3 232 247 A R > - 0 0 182 -2,-0.5 3,-2.3 1,-0.1 7,-0.1 -0.570 38.1 -91.4 -75.3 143.2 12.1 17.7 -2.7 233 248 A P T 3 S+ 0 0 97 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.305 115.4 18.6 -50.1 121.9 13.1 20.4 -0.1 234 249 A G T 3 S+ 0 0 40 1,-0.2 2,-1.5 -2,-0.1 3,-0.2 0.339 84.3 127.3 98.6 -10.0 9.8 21.9 1.0 235 250 A D <> + 0 0 47 -3,-2.3 4,-1.9 1,-0.2 -1,-0.2 -0.619 26.4 170.8 -82.3 87.6 7.4 19.1 -0.1 236 251 A R H > S+ 0 0 102 -2,-1.5 4,-2.1 1,-0.2 5,-0.2 0.817 72.0 64.0 -67.7 -30.6 5.6 18.6 3.2 237 252 A E H > S+ 0 0 162 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.943 109.3 37.3 -59.7 -46.9 3.1 16.3 1.5 238 253 A R H > S+ 0 0 100 2,-0.2 4,-2.3 1,-0.2 -2,-0.2 0.898 110.8 61.7 -79.1 -29.6 5.7 13.8 0.6 239 254 A L H < S+ 0 0 0 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.896 114.8 34.8 -56.4 -40.2 7.6 14.3 3.9 240 255 A L H < S+ 0 0 50 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.741 120.5 47.0 -91.3 -19.6 4.4 13.1 5.7 241 256 A S H < S+ 0 0 66 -4,-1.7 -2,-0.2 -5,-0.2 -3,-0.2 0.728 79.9 108.4 -97.2 -14.1 3.2 10.5 3.3 242 257 A I S < S- 0 0 3 -4,-2.3 -13,-0.0 -5,-0.2 -11,-0.0 -0.295 81.8-103.4 -61.8 135.5 6.4 8.6 2.5 243 258 A P > - 0 0 66 0, 0.0 4,-2.4 0, 0.0 3,-0.5 -0.333 24.4-124.3 -54.5 139.2 6.3 5.1 4.1 244 259 A A H > S+ 0 0 19 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.882 110.0 53.6 -56.8 -36.1 8.4 4.9 7.3 245 260 A E H > S+ 0 0 117 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.890 107.7 49.1 -72.0 -30.6 10.3 2.0 5.9 246 261 A E H > S+ 0 0 94 -3,-0.5 4,-2.4 2,-0.2 -1,-0.2 0.917 111.4 49.7 -71.8 -39.3 11.3 3.8 2.7 247 262 A L H X S+ 0 0 0 -4,-2.4 4,-1.6 1,-0.2 -2,-0.2 0.933 112.7 47.5 -63.6 -41.6 12.4 6.8 4.6 248 263 A L H X S+ 0 0 3 -4,-2.3 4,-2.2 -5,-0.2 -2,-0.2 0.941 111.0 51.3 -64.0 -44.3 14.5 4.6 6.9 249 264 A R H X S+ 0 0 126 -4,-2.5 4,-1.5 1,-0.2 -2,-0.2 0.890 105.4 56.1 -57.2 -42.0 16.0 2.7 4.0 250 265 A A H < S+ 0 0 7 -4,-2.4 -1,-0.2 2,-0.2 -2,-0.2 0.909 110.6 44.1 -59.0 -45.5 17.0 6.0 2.2 251 266 A A H >< S+ 0 0 1 -4,-1.6 3,-2.6 1,-0.2 4,-0.2 0.945 112.2 50.0 -60.8 -53.8 19.1 7.1 5.2 252 267 A L H >< S+ 0 0 63 -4,-2.2 3,-1.6 1,-0.3 -1,-0.2 0.767 96.6 73.1 -62.8 -20.8 20.7 3.9 5.9 253 268 A S T 3< S+ 0 0 59 -4,-1.5 -1,-0.3 1,-0.3 -2,-0.2 0.537 90.1 61.0 -71.7 -5.3 21.6 3.7 2.2 254 269 A L T X S- 0 0 16 -3,-2.6 3,-1.4 1,-0.3 -1,-0.3 0.546 85.2-170.2 -95.4 -3.7 24.2 6.4 2.9 255 270 A G T < - 0 0 45 -3,-1.6 -1,-0.3 -4,-0.2 3,-0.1 -0.345 64.9 -6.6 53.0-128.1 26.2 4.3 5.4 256 271 A P T 3 S+ 0 0 120 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 0.466 114.2 83.2 -88.3 -12.5 28.8 6.3 7.3 257 272 A G S < S+ 0 0 35 -3,-1.4 2,-0.2 1,-0.1 -2,-0.1 -0.116 94.7 55.9 -82.3 35.6 28.5 9.6 5.5 258 273 A V + 0 0 12 -2,-0.3 2,-0.4 -3,-0.1 -1,-0.1 -0.875 63.1 173.6-168.1 119.5 25.5 10.2 7.8 259 274 A M - 0 0 103 -2,-0.2 2,-0.3 2,-0.1 -164,-0.1 -0.999 21.2-137.7-133.4 149.2 25.6 10.2 11.5 260 275 A Y + 0 0 13 -166,-0.6 -164,-0.1 -2,-0.4 -129,-0.1 -0.732 40.9 109.6-104.8 153.6 22.8 11.1 13.8 261 276 A G - 0 0 0 -2,-0.3 -49,-0.1 -131,-0.2 -50,-0.1 -0.904 64.6 -42.5 164.1 176.1 22.8 13.1 16.9 262 277 A P - 0 0 2 0, 0.0 -49,-2.7 0, 0.0 2,-0.4 -0.117 50.5-144.5 -61.2 155.6 21.7 16.4 18.5 263 278 A V B -n 213 0D 0 -51,-0.2 2,-2.0 -118,-0.0 6,-0.5 -0.978 17.2-130.7-125.3 130.4 22.2 19.6 16.6 264 279 A V + 0 0 35 -51,-2.3 6,-0.1 -2,-0.4 8,-0.1 -0.603 51.7 154.6 -78.2 84.4 23.1 23.0 18.0 265 280 A D - 0 0 14 -2,-2.0 -1,-0.2 4,-0.2 5,-0.2 0.446 58.7-112.8 -97.8 -6.7 20.2 24.5 16.0 266 281 A G S S+ 0 0 48 3,-2.5 4,-0.2 -3,-0.2 -2,-0.1 0.538 103.8 65.2 87.6 -0.1 19.3 27.7 18.0 267 282 A R S S+ 0 0 104 2,-0.5 3,-0.2 -125,-0.1 -124,-0.1 0.659 117.7 5.7-124.8 -62.2 15.9 26.2 19.0 268 283 A V S S+ 0 0 4 1,-0.3 2,-0.7 -5,-0.2 -75,-0.2 0.935 140.8 35.9 -86.0 -47.6 16.2 23.2 21.3 269 284 A L + 0 0 1 -6,-0.5 -3,-2.5 1,-0.1 -2,-0.5 -0.914 65.5 174.5-104.3 110.5 20.0 23.4 21.7 270 285 A R + 0 0 181 -2,-0.7 2,-0.3 -4,-0.2 -1,-0.1 0.597 67.0 4.7 -96.8 -11.9 21.0 27.0 21.8 271 286 A R S S- 0 0 139 -81,-0.0 -1,-0.2 0, 0.0 -6,-0.1 -0.977 99.1 -60.4-160.0 166.8 24.7 26.4 22.6 272 287 A H > - 0 0 51 -2,-0.3 4,-2.0 1,-0.2 -63,-0.1 -0.290 47.9-134.1 -51.4 130.8 27.3 23.6 23.0 273 288 A P H > S+ 0 0 1 0, 0.0 4,-0.7 0, 0.0 -1,-0.2 0.768 102.2 45.8 -67.6 -25.3 26.0 21.4 25.9 274 289 A I H >> S+ 0 0 3 2,-0.2 4,-0.8 1,-0.2 3,-0.8 0.911 110.3 52.1 -81.8 -40.8 29.4 21.3 27.6 275 290 A E H >> S+ 0 0 50 1,-0.3 3,-1.1 2,-0.2 4,-0.6 0.897 102.8 61.9 -61.1 -32.1 30.2 25.0 27.3 276 291 A A H ><>S+ 0 0 6 -4,-2.0 5,-1.7 1,-0.3 3,-1.3 0.872 93.9 62.0 -62.9 -33.6 26.8 25.7 28.9 277 292 A L H X<5S+ 0 0 3 -3,-0.8 3,-1.8 -4,-0.7 5,-0.3 0.854 95.2 61.6 -59.5 -29.0 27.9 23.9 32.0 278 293 A R H <<5S+ 0 0 148 -3,-1.1 -1,-0.3 -4,-0.8 -2,-0.2 0.762 100.4 53.6 -72.2 -18.0 30.6 26.5 32.4 279 294 A Y T <<5S- 0 0 174 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.285 128.5 -98.3 -99.0 14.2 27.9 29.2 32.6 280 295 A G T X 5S+ 0 0 19 -3,-1.8 3,-1.6 -4,-0.1 4,-0.2 0.630 71.8 148.1 85.7 20.3 26.2 27.3 35.5 281 296 A A T 3 S+ 0 0 3 -5,-0.3 3,-2.2 -6,-0.2 -1,-0.3 -0.112 79.8 145.3-132.1 36.4 23.8 22.6 36.0 283 298 A S T < S+ 0 0 63 -3,-1.6 -2,-0.1 1,-0.3 -1,-0.1 0.794 75.1 40.1 -55.2 -34.0 25.3 24.3 39.0 284 299 A G T 3 S+ 0 0 66 -4,-0.2 -1,-0.3 -3,-0.1 80,-0.1 0.353 92.6 103.2-102.1 20.5 23.5 22.2 41.7 285 300 A I < - 0 0 30 -3,-2.2 -85,-0.2 -96,-0.1 78,-0.1 -0.840 57.7-149.0-110.0 113.2 23.7 18.9 40.0 286 301 A P - 0 0 21 0, 0.0 -85,-1.8 0, 0.0 2,-0.3 -0.450 19.6-162.0 -73.2 151.5 26.2 16.2 41.1 287 302 A I E -ij 201 365B 0 77,-2.2 79,-2.1 -87,-0.2 2,-0.4 -0.974 22.1-156.1-136.4 154.0 27.5 13.8 38.5 288 303 A L E +ij 202 366B 0 -87,-1.9 -85,-2.6 -2,-0.3 2,-0.3 -0.995 31.5 168.6-122.5 127.7 29.2 10.5 38.2 289 304 A I E +ij 203 367B 4 77,-2.9 79,-1.8 -2,-0.4 2,-0.3 -0.990 4.3 145.9-145.5 144.8 31.1 10.1 34.9 290 305 A G E -ij 204 368B 2 -87,-2.1 -85,-2.4 -2,-0.3 -84,-0.5 -0.982 27.2-126.1-166.8-179.3 33.6 7.8 33.4 291 306 A V E - j 0 369B 4 77,-1.4 79,-2.9 -2,-0.3 2,-0.5 -0.948 24.8-111.9-140.0 155.2 35.1 6.0 30.4 292 307 A T E > - j 0 370B 3 -2,-0.3 3,-1.4 77,-0.2 79,-0.2 -0.764 50.4-102.9 -81.9 123.5 35.9 2.5 29.1 293 308 A K T 3 S- 0 0 100 77,-2.4 -1,-0.1 -2,-0.5 76,-0.0 -0.216 96.0 -9.4 -50.2 129.7 39.7 2.2 28.8 294 309 A D T >> S+ 0 0 49 1,-0.1 3,-2.1 2,-0.1 4,-0.6 0.829 80.8 167.3 55.4 34.3 40.9 2.4 25.2 295 310 A E H X> + 0 0 0 -3,-1.4 3,-1.3 1,-0.3 4,-0.5 0.832 64.0 64.2 -59.0 -31.2 37.4 2.3 23.9 296 311 A Y H >4 S+ 0 0 23 1,-0.3 3,-0.7 2,-0.2 4,-0.3 0.760 89.9 67.2 -70.6 -13.7 38.2 3.3 20.3 297 312 A N H X4 S+ 0 0 29 -3,-2.1 3,-1.3 1,-0.2 -1,-0.3 0.888 94.3 60.2 -68.4 -26.3 40.3 0.2 19.8 298 313 A L H X< S+ 0 0 36 -3,-1.3 3,-1.7 -4,-0.6 4,-0.5 0.783 88.8 71.8 -69.0 -22.8 37.0 -1.6 20.1 299 314 A F T < + 0 0 43 -4,-1.9 3,-1.2 1,-0.1 -1,-0.3 -0.593 61.5 166.8-135.9 76.8 35.0 -0.8 11.3 304 319 A P T >> + 0 0 61 0, 0.0 3,-2.3 0, 0.0 4,-0.6 0.653 62.5 88.7 -62.8 -15.0 38.1 -2.9 10.4 305 320 A S H >> S+ 0 0 33 1,-0.3 3,-1.7 2,-0.2 4,-1.2 0.865 76.5 67.6 -56.3 -34.1 39.1 -0.4 7.7 306 321 A W H <4 S+ 0 0 3 -3,-1.2 -1,-0.3 1,-0.3 3,-0.1 0.837 99.0 51.9 -46.2 -38.7 41.0 1.4 10.4 307 322 A T H <4 S+ 0 0 61 -3,-2.3 -1,-0.3 -4,-0.2 -2,-0.2 0.607 101.9 59.0 -79.0 -13.2 43.3 -1.6 10.5 308 323 A K H << S+ 0 0 154 -3,-1.7 -1,-0.2 -4,-0.6 -2,-0.2 0.905 84.9 94.9 -85.1 -36.0 44.0 -1.7 6.8 309 324 A L S < S- 0 0 46 -4,-1.2 2,-0.0 1,-0.1 -3,-0.0 -0.118 73.0-122.3 -55.8 139.3 45.5 1.9 6.5 310 325 A G > - 0 0 44 1,-0.1 4,-2.5 4,-0.0 5,-0.2 -0.307 40.3 -91.3 -78.6 171.6 49.2 2.6 6.6 311 326 A E H > S+ 0 0 141 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.862 125.7 44.8 -53.4 -45.1 50.6 5.0 9.2 312 327 A K H > S+ 0 0 67 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.920 114.8 46.0 -65.2 -51.1 50.3 8.1 6.9 313 328 A E H > S+ 0 0 126 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.866 113.0 53.9 -57.3 -39.5 46.8 7.3 5.6 314 329 A L H X S+ 0 0 2 -4,-2.5 4,-2.8 2,-0.2 -2,-0.2 0.940 110.5 43.3 -57.1 -58.0 45.8 6.6 9.2 315 330 A L H X S+ 0 0 33 -4,-2.2 4,-2.7 2,-0.2 5,-0.2 0.849 111.6 53.3 -63.6 -43.4 47.0 9.9 10.6 316 331 A D H X S+ 0 0 87 -4,-2.7 4,-1.8 2,-0.2 -1,-0.2 0.928 111.7 48.2 -60.9 -39.8 45.5 11.8 7.7 317 332 A R H X S+ 0 0 50 -4,-2.1 4,-2.3 2,-0.2 -2,-0.2 0.946 111.5 47.8 -61.6 -49.7 42.2 10.1 8.5 318 333 A I H X S+ 0 0 0 -4,-2.8 4,-3.1 1,-0.2 5,-0.4 0.948 111.0 53.2 -60.5 -42.4 42.4 10.8 12.2 319 334 A N H X S+ 0 0 60 -4,-2.7 4,-1.6 1,-0.2 -1,-0.2 0.890 108.1 49.3 -58.5 -39.6 43.2 14.4 11.4 320 335 A R H < S+ 0 0 224 -4,-1.8 -1,-0.2 -5,-0.2 -2,-0.2 0.944 117.7 40.4 -68.7 -41.5 40.2 14.7 9.2 321 336 A E H < S+ 0 0 100 -4,-2.3 -2,-0.2 -5,-0.1 -1,-0.2 0.876 139.8 1.3 -73.4 -41.5 37.8 13.3 11.8 322 337 A V H < S+ 0 0 23 -4,-3.1 -3,-0.2 -5,-0.2 -2,-0.2 0.262 104.5 156.4-138.5 15.6 39.1 14.8 15.1 323 338 A G < + 0 0 25 -4,-1.6 2,-0.1 -5,-0.4 -4,-0.1 -0.018 38.3 86.1 -78.4-176.1 42.0 17.2 14.2 324 339 A P - 0 0 110 0, 0.0 -4,-0.0 0, 0.0 -5,-0.0 0.526 57.3-163.0 -77.7 152.6 44.0 19.2 14.2 325 340 A V - 0 0 19 -2,-0.1 -2,-0.1 4,-0.0 5,-0.1 -0.910 16.6-131.5-105.2 113.6 46.4 17.2 16.2 326 341 A P > - 0 0 39 0, 0.0 4,-1.8 0, 0.0 3,-0.3 -0.122 19.4-117.8 -63.2 159.5 49.1 19.4 17.8 327 342 A E H > S+ 0 0 131 1,-0.2 4,-2.7 2,-0.2 5,-0.1 0.884 113.7 60.2 -68.5 -31.6 52.7 18.1 17.4 328 343 A E H > S+ 0 0 85 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.829 104.0 50.9 -64.4 -32.9 53.1 17.8 21.1 329 344 A A H > S+ 0 0 0 -3,-0.3 4,-2.7 2,-0.2 -1,-0.2 0.982 107.9 50.8 -68.9 -52.0 50.2 15.3 21.1 330 345 A I H < S+ 0 0 52 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.910 110.4 52.4 -48.1 -45.6 51.8 13.2 18.3 331 346 A R H < S+ 0 0 176 -4,-2.7 -1,-0.2 2,-0.2 -2,-0.2 0.913 107.3 49.6 -62.2 -45.3 55.0 13.2 20.4 332 347 A Y H < 0 0 80 -4,-2.2 -1,-0.2 1,-0.1 -2,-0.2 0.937 360.0 360.0 -55.7 -45.5 53.2 12.0 23.5 333 348 A Y < 0 0 29 -4,-2.7 -2,-0.2 -5,-0.1 -3,-0.2 0.989 360.0 360.0 -70.7 360.0 51.6 9.3 21.4 334 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 335 359 A W > 0 0 101 0, 0.0 4,-2.5 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 -29.0 46.6 1.5 14.4 336 360 A Q T 4 + 0 0 115 2,-0.2 4,-0.4 1,-0.2 -39,-0.0 0.922 360.0 42.3 -61.7 -43.5 46.6 0.6 18.1 337 361 A T T >4 S+ 0 0 56 1,-0.2 3,-1.1 2,-0.2 4,-0.3 0.961 119.4 42.3 -67.5 -52.1 49.0 3.5 19.0 338 362 A W T >> S+ 0 0 43 1,-0.3 3,-1.4 2,-0.2 4,-0.6 0.750 102.2 66.5 -71.8 -24.1 47.3 6.2 16.7 339 363 A L H 3X S+ 0 0 0 -4,-2.5 4,-2.1 1,-0.3 -1,-0.3 0.704 83.0 78.5 -71.5 -11.8 43.7 5.2 17.6 340 364 A R H <> S+ 0 0 86 -3,-1.1 4,-2.6 -4,-0.4 -1,-0.3 0.853 86.3 60.3 -59.5 -29.8 44.5 6.4 21.1 341 365 A I H <> S+ 0 0 0 -3,-1.4 4,-2.9 -4,-0.3 5,-0.2 0.920 103.3 49.3 -62.1 -42.7 43.9 9.9 19.6 342 366 A M H X S+ 0 0 3 -4,-0.6 4,-2.6 2,-0.2 5,-0.4 0.925 109.5 51.9 -62.9 -44.3 40.4 8.9 18.7 343 367 A T H X>S+ 0 0 12 -4,-2.1 4,-2.1 1,-0.2 5,-2.1 0.957 113.7 44.2 -55.0 -49.6 39.8 7.6 22.2 344 368 A Y H <>S+ 0 0 0 -4,-2.6 5,-3.2 3,-0.2 6,-0.3 0.960 117.8 42.4 -61.7 -50.2 41.0 10.9 23.7 345 369 A R H <5S+ 0 0 59 -4,-2.9 5,-0.2 3,-0.2 -1,-0.2 0.854 122.5 36.5 -69.9 -36.5 39.1 13.2 21.4 346 370 A V H <5S+ 0 0 28 -4,-2.6 -139,-0.2 -5,-0.2 -1,-0.2 0.848 137.2 6.7 -84.2 -36.1 35.8 11.4 21.3 347 371 A F T X5S+ 0 0 3 -4,-2.1 4,-1.6 -5,-0.4 -3,-0.2 0.778 124.3 45.9-114.5 -53.0 35.6 10.2 24.9 348 372 A V H > S+ 0 0 0 -6,-0.3 4,-2.0 -5,-0.2 -1,-0.2 0.895 112.0 51.7 -65.7 -35.0 34.6 15.6 26.7 351 375 A M H X S+ 0 0 6 -4,-1.6 4,-2.6 2,-0.2 5,-0.2 0.936 112.2 45.7 -62.4 -48.6 34.5 13.7 30.0 352 376 A L H X S+ 0 0 3 -4,-2.7 4,-2.7 1,-0.2 5,-0.2 0.905 112.6 50.6 -63.3 -37.6 37.3 15.9 31.5 353 377 A R H X S+ 0 0 65 -4,-2.8 4,-2.0 -5,-0.3 -1,-0.2 0.902 112.3 47.4 -68.0 -37.2 35.7 19.1 30.2 354 378 A T H X S+ 0 0 4 -4,-2.0 4,-2.4 -5,-0.2 5,-0.2 0.929 114.2 46.3 -64.4 -48.1 32.4 18.1 31.8 355 379 A A H X S+ 0 0 0 -4,-2.6 4,-2.6 1,-0.2 5,-0.2 0.911 112.9 49.7 -63.5 -44.1 34.0 17.2 35.1 356 380 A D H X S+ 0 0 53 -4,-2.7 4,-2.0 -5,-0.2 -1,-0.2 0.891 111.0 50.1 -63.6 -39.7 36.1 20.4 35.1 357 381 A A H X S+ 0 0 6 -4,-2.0 4,-0.9 -5,-0.2 -2,-0.2 0.935 113.5 43.9 -64.9 -47.0 32.9 22.5 34.4 358 382 A Q H ><>S+ 0 0 0 -4,-2.4 5,-2.1 1,-0.2 3,-0.9 0.937 113.3 51.1 -68.1 -39.4 30.9 20.9 37.2 359 383 A A H ><5S+ 0 0 25 -4,-2.6 3,-1.7 1,-0.3 -1,-0.2 0.903 105.8 55.8 -64.8 -35.9 33.7 21.1 39.7 360 384 A A H 3<5S+ 0 0 83 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.771 104.7 54.0 -66.0 -18.9 34.2 24.7 38.9 361 385 A Q T <<5S- 0 0 67 -4,-0.9 -1,-0.3 -3,-0.9 -2,-0.2 0.497 120.1-111.4 -91.2 -1.1 30.5 25.2 39.8 362 386 A G T < 5S+ 0 0 64 -3,-1.7 -3,-0.2 -4,-0.4 2,-0.2 0.499 71.3 141.0 85.7 8.8 31.2 23.5 43.2 363 387 A A < - 0 0 14 -5,-2.1 -1,-0.3 -78,-0.1 2,-0.2 -0.539 60.2-102.3 -80.7 150.0 29.1 20.4 42.3 364 388 A D - 0 0 87 -2,-0.2 -77,-2.2 -3,-0.1 2,-0.4 -0.526 40.4-172.2 -71.9 140.4 30.2 17.0 43.4 365 389 A V E -j 287 0B 0 72,-0.3 72,-3.1 -2,-0.2 2,-0.5 -0.999 10.9-168.2-132.8 131.3 31.9 15.0 40.6 366 390 A Y E -j 288 0B 16 -79,-2.1 -77,-2.9 -2,-0.4 2,-0.3 -0.991 13.8-166.2-120.9 120.2 32.9 11.3 40.8 367 391 A M E +j 289 0B 1 -2,-0.5 78,-3.1 76,-0.4 2,-0.3 -0.872 7.9 178.3-111.3 144.8 35.1 10.1 37.9 368 392 A Y E -jk 290 445B 0 -79,-1.8 -77,-1.4 -2,-0.3 2,-0.4 -0.949 22.2-151.7-137.5 161.3 36.0 6.6 36.9 369 393 A R E -jk 291 446B 33 76,-2.5 78,-2.3 -2,-0.3 2,-0.7 -1.000 17.7-145.4-126.2 130.4 37.9 4.5 34.4 370 394 A F E +jk 292 447B 1 -79,-2.9 -77,-2.4 -2,-0.4 78,-0.2 -0.874 28.4 163.0 -99.9 109.3 36.7 1.0 33.6 371 395 A D + 0 0 46 76,-3.0 77,-0.2 -2,-0.7 -1,-0.1 0.450 27.7 125.3-105.5 -7.1 39.8 -1.2 32.9 372 396 A Y - 0 0 15 75,-0.8 2,-0.5 1,-0.1 -79,-0.1 -0.381 62.0-128.1 -64.0 128.6 38.3 -4.7 33.3 373 397 A E + 0 0 182 -2,-0.1 -1,-0.1 2,-0.0 -2,-0.1 -0.690 46.6 151.3 -79.8 126.0 38.9 -6.8 30.1 374 398 A T - 0 0 18 -2,-0.5 2,-0.1 31,-0.0 22,-0.0 -0.971 49.3 -90.7-155.5 143.2 35.5 -8.2 29.0 375 399 A P 0 0 61 0, 0.0 21,-0.2 0, 0.0 23,-0.0 -0.403 360.0 360.0 -73.0 140.8 34.4 -9.1 25.5 376 400 A V 0 0 83 -2,-0.1 5,-0.1 -78,-0.0 4,-0.0 -0.030 360.0 360.0 -56.6 360.0 32.6 -6.5 23.3 377 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 378 408 A C 0 0 36 0, 0.0 -79,-0.1 0, 0.0 -80,-0.1 0.000 360.0 360.0 360.0 12.7 30.0 2.8 20.8 379 409 A H + 0 0 32 1,-0.2 2,-0.2 -81,-0.1 -81,-0.1 0.733 360.0 168.0 88.5 31.5 31.5 -0.2 22.6 380 410 A A - 0 0 16 1,-0.1 -1,-0.2 -176,-0.1 3,-0.1 -0.518 16.5-165.8 -66.8 141.7 31.1 0.9 26.2 381 411 A L + 0 0 23 -2,-0.2 4,-0.3 1,-0.1 -1,-0.1 0.456 64.6 82.0-114.5 -2.2 31.8 -2.1 28.4 382 412 A E >> + 0 0 0 1,-0.2 4,-2.3 2,-0.1 3,-1.0 0.741 65.5 94.1 -72.3 -24.9 30.4 -1.2 31.9 383 413 A L H 3> S+ 0 0 12 1,-0.3 4,-2.6 2,-0.2 5,-0.3 0.792 80.4 44.5 -53.5 -51.6 26.8 -2.0 31.3 384 414 A P H 3>>S+ 0 0 21 0, 0.0 5,-2.0 0, 0.0 4,-0.8 0.836 117.5 48.3 -65.3 -26.2 26.2 -5.5 32.5 385 415 A F H <45S+ 0 0 0 -3,-1.0 28,-0.4 -4,-0.3 -2,-0.2 0.913 111.6 48.0 -76.7 -43.7 28.2 -4.8 35.7 386 416 A V H <5S+ 0 0 0 -4,-2.3 -1,-0.2 1,-0.2 -3,-0.2 0.927 121.0 36.8 -60.4 -44.6 26.4 -1.6 36.4 387 417 A F H <5S- 0 0 0 -4,-2.6 -277,-0.3 -5,-0.2 -1,-0.2 0.607 102.8-129.1 -82.4 -12.2 22.9 -3.2 35.9 388 418 A H T <5 + 0 0 32 -4,-0.8 -3,-0.2 -5,-0.3 3,-0.2 0.934 66.0 136.4 52.6 50.4 24.0 -6.6 37.5 389 419 A N > < + 0 0 0 -5,-2.0 3,-0.9 -6,-0.2 -4,-0.1 -0.413 8.0 131.3-119.6 48.2 22.6 -8.2 34.3 390 420 A L T 3 S+ 0 0 22 -6,-0.2 -1,-0.1 1,-0.2 -5,-0.1 0.660 72.1 57.4 -74.4 -15.6 25.3 -10.7 33.7 391 421 A H T 3 S+ 0 0 111 -3,-0.2 -1,-0.2 -7,-0.1 -2,-0.1 0.295 85.5 109.4 -98.5 -6.4 22.7 -13.4 33.2 392 422 A Q S X S- 0 0 26 -3,-0.9 3,-1.0 1,-0.1 5,-0.2 -0.404 73.3-102.6 -82.3 156.6 20.7 -11.7 30.4 393 423 A P T 3 S+ 0 0 86 0, 0.0 -289,-0.2 0, 0.0 -1,-0.1 -0.371 107.3 30.9 -70.5 145.1 20.4 -12.6 26.8 394 424 A G T 3 S+ 0 0 62 1,-0.4 2,-0.4 -2,-0.1 -2,-0.0 0.329 93.0 118.5 85.9 -18.3 22.4 -10.5 24.3 395 425 A V S < S- 0 0 23 -3,-1.0 2,-3.3 1,-0.1 -1,-0.4 -0.749 80.5-114.9 -82.2 132.8 25.0 -10.1 27.1 396 426 A A + 0 0 27 -2,-0.4 2,-1.0 -21,-0.2 -1,-0.1 -0.333 50.4 168.8 -69.2 69.2 28.4 -11.6 26.2 397 427 A N + 0 0 96 -2,-3.3 2,-0.3 -5,-0.2 -3,-0.1 -0.776 8.1 162.5 -81.0 95.9 28.1 -14.2 28.9 398 428 A F - 0 0 134 -2,-1.0 -2,-0.0 2,-0.1 0, 0.0 -0.841 43.3 -86.8-117.4 157.7 30.9 -16.6 28.2 399 429 A V S S+ 0 0 148 -2,-0.3 -1,-0.1 2,-0.1 2,-0.0 -0.122 85.9 49.2 -60.4 156.4 32.5 -19.3 30.4 400 430 A G S S+ 0 0 40 4,-0.0 -2,-0.1 0, 0.0 0, 0.0 0.025 85.2 48.6 99.9 155.3 35.4 -18.3 32.8 401 431 A N > + 0 0 97 1,-0.1 4,-2.8 3,-0.1 5,-0.3 0.703 60.7 147.7 65.8 15.3 36.0 -15.5 35.3 402 432 A R H > S+ 0 0 155 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.937 71.9 42.0 -62.4 -49.7 32.6 -15.9 37.1 403 433 A P H > S+ 0 0 86 0, 0.0 4,-2.1 0, 0.0 -1,-0.2 0.900 116.5 51.8 -61.2 -35.2 33.7 -14.9 40.6 404 434 A E H > S+ 0 0 85 2,-0.2 4,-2.2 1,-0.2 5,-0.2 0.937 110.7 46.6 -63.8 -46.7 35.7 -12.0 39.1 405 435 A R H X S+ 0 0 18 -4,-2.8 4,-2.2 1,-0.2 -1,-0.2 0.902 111.9 51.0 -66.3 -37.1 32.8 -10.8 37.1 406 436 A E H X S+ 0 0 71 -4,-2.5 4,-2.6 -5,-0.3 -1,-0.2 0.906 108.2 53.5 -62.6 -41.5 30.4 -11.0 40.0 407 437 A A H X S+ 0 0 51 -4,-2.1 4,-1.6 -5,-0.2 -2,-0.2 0.905 109.5 45.7 -64.9 -41.4 32.9 -9.1 42.2 408 438 A I H X S+ 0 0 4 -4,-2.2 4,-2.6 2,-0.2 5,-0.3 0.902 111.9 52.8 -71.5 -34.3 33.1 -6.1 39.8 409 439 A A H X S+ 0 0 0 -4,-2.2 4,-2.6 1,-0.2 5,-0.5 0.911 106.6 53.4 -60.2 -41.9 29.4 -6.1 39.4 410 440 A N H X S+ 0 0 68 -4,-2.6 4,-0.8 1,-0.2 -1,-0.2 0.855 111.5 46.5 -65.7 -31.3 29.1 -6.0 43.1 411 441 A E H X S+ 0 0 29 -4,-1.6 4,-1.3 -5,-0.1 -2,-0.2 0.953 121.0 34.6 -69.2 -49.8 31.4 -2.9 43.2 412 442 A M H X S+ 0 0 0 -4,-2.6 4,-2.6 2,-0.2 5,-0.3 0.913 115.3 52.9 -77.2 -45.3 29.7 -0.9 40.3 413 443 A H H X S+ 0 0 0 -4,-2.6 4,-2.2 -28,-0.4 -1,-0.2 0.948 114.7 41.9 -56.9 -46.2 26.1 -1.9 40.9 414 444 A Y H X S+ 0 0 76 -4,-0.8 4,-2.2 -5,-0.5 -1,-0.2 0.804 112.6 53.9 -77.4 -25.1 26.1 -0.8 44.5 415 445 A A H X S+ 0 0 0 -4,-1.3 4,-2.2 2,-0.2 -1,-0.2 0.914 110.1 47.4 -68.4 -41.9 28.1 2.3 43.8 416 446 A W H X S+ 0 0 0 -4,-2.6 4,-2.8 2,-0.2 5,-0.2 0.920 113.3 49.1 -65.2 -41.8 25.6 3.4 41.2 417 447 A L H X S+ 0 0 0 -4,-2.2 4,-2.3 -5,-0.3 -2,-0.2 0.919 111.2 49.4 -62.7 -42.7 22.8 2.6 43.7 418 448 A S H X>S+ 0 0 14 -4,-2.2 4,-2.6 1,-0.2 6,-0.9 0.900 111.2 49.4 -65.5 -37.5 24.5 4.6 46.4 419 449 A F H X5S+ 0 0 0 -4,-2.2 4,-2.0 4,-0.2 -2,-0.2 0.937 112.1 48.0 -65.7 -45.7 25.0 7.6 44.1 420 450 A A H <5S+ 0 0 0 -4,-2.8 -2,-0.2 1,-0.2 -334,-0.2 0.877 117.4 43.2 -61.5 -35.6 21.3 7.5 43.1 421 451 A R H <5S+ 0 0 101 -4,-2.3 -2,-0.2 -5,-0.2 -1,-0.2 0.928 138.4 0.6 -76.0 -41.0 20.2 7.2 46.7 422 452 A T H <5S- 0 0 85 -4,-2.6 -3,-0.2 2,-0.2 -2,-0.2 0.542 92.7-106.2-133.0 -15.0 22.5 9.8 48.4 423 453 A G S < S- 0 0 38 5,-0.1 3,-2.0 3,-0.1 5,-0.1 -0.917 81.7 -57.5 154.8-176.9 30.6 2.4 51.0 428 458 A A T 3 S+ 0 0 109 1,-0.3 -1,-0.1 -2,-0.3 -2,-0.1 0.588 115.5 77.1 -72.0 -6.9 31.8 -1.0 52.0 429 459 A H T 3 S+ 0 0 50 -18,-0.1 -1,-0.3 -15,-0.1 -14,-0.1 0.566 88.0 72.2 -72.6 -9.5 31.1 -2.4 48.5 430 460 A L S < S- 0 0 13 -3,-2.0 -3,-0.1 1,-0.1 4,-0.0 -0.905 81.2-135.5-107.9 138.7 34.3 -0.6 47.4 431 461 A P S S+ 0 0 75 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.630 89.8 3.2 -68.8 -16.0 37.8 -1.8 48.3 432 462 A E S S- 0 0 85 -5,-0.1 -5,-0.1 20,-0.0 20,-0.0 -0.982 97.2 -72.0-158.8 168.0 38.9 1.7 49.1 433 463 A A - 0 0 68 -2,-0.3 20,-0.1 1,-0.1 -5,-0.0 -0.290 33.8-140.1 -69.8 150.7 37.3 5.2 49.2 434 464 A W - 0 0 1 11,-0.1 -8,-0.2 19,-0.0 2,-0.1 -0.888 22.0-151.6-104.9 101.7 36.4 7.0 46.0 435 465 A P - 0 0 34 0, 0.0 -68,-0.4 0, 0.0 10,-0.1 -0.448 23.7-101.8 -73.8 148.8 37.3 10.7 46.5 436 466 A A - 0 0 31 -70,-0.1 2,-0.5 -2,-0.1 7,-0.4 -0.410 38.8-106.4 -63.2 144.5 35.3 13.3 44.6 437 467 A Y + 0 0 5 -72,-3.1 -72,-0.3 5,-0.2 2,-0.3 -0.663 49.4 168.4 -69.8 119.2 37.1 14.8 41.6 438 468 A T >> - 0 0 38 -2,-0.5 4,-2.2 -74,-0.1 3,-0.8 -0.903 50.0-111.8-128.9 158.8 38.3 18.4 42.4 439 469 A N T 34 S+ 0 0 115 -2,-0.3 -1,-0.1 1,-0.2 -83,-0.0 0.827 115.0 64.5 -56.7 -30.8 40.6 20.6 40.4 440 470 A E T 34 S+ 0 0 168 1,-0.1 -1,-0.2 -3,-0.0 -3,-0.1 0.827 124.8 1.5 -58.7 -47.6 43.0 20.1 43.3 441 471 A R T <4 S- 0 0 117 -3,-0.8 15,-0.4 2,-0.1 -2,-0.2 0.661 74.5-148.0-121.9 -28.9 43.7 16.3 43.0 442 472 A K < - 0 0 27 -4,-2.2 14,-2.0 13,-0.2 16,-0.2 0.917 30.4-174.0 54.9 45.1 41.7 15.1 40.0 443 473 A A E - L 0 455B 0 -7,-0.4 -76,-0.4 12,-0.2 2,-0.3 -0.386 8.2-174.2 -67.8 145.1 41.1 11.7 41.6 444 474 A A E - L 0 454B 0 10,-2.5 10,-2.4 -78,-0.1 2,-0.5 -0.997 22.2-126.8-137.8 146.0 39.5 8.9 39.6 445 475 A F E -kL 368 453B 0 -78,-3.1 -76,-2.5 -2,-0.3 2,-0.6 -0.798 19.9-149.9 -92.5 135.5 38.3 5.4 40.6 446 476 A V E -kL 369 452B 0 6,-3.4 6,-1.6 -2,-0.5 2,-0.6 -0.896 4.0-152.9-109.1 114.3 39.6 2.6 38.5 447 477 A F E +k 370 0B 0 -78,-2.3 -76,-3.0 -2,-0.6 -75,-0.8 -0.790 42.9 117.0 -87.7 120.2 37.4 -0.5 38.2 448 478 A S S > S- 0 0 22 -2,-0.6 3,-0.8 -77,-0.2 -76,-0.1 -0.862 84.0 -62.6-159.8-174.0 39.3 -3.6 37.5 449 479 A A T 3 S+ 0 0 74 1,-0.3 2,-0.1 -2,-0.2 -2,-0.1 0.668 140.8 25.9 -55.3 -24.0 40.2 -7.0 38.9 450 480 A A T 3 S- 0 0 71 -4,-0.1 -1,-0.3 2,-0.0 -4,-0.1 -0.666 94.4-153.5-140.7 76.8 41.8 -4.9 41.7 451 481 A S < + 0 0 6 -3,-0.8 2,-0.3 -2,-0.1 -4,-0.2 -0.159 27.4 150.3 -57.6 144.9 39.9 -1.6 41.8 452 482 A H E -L 446 0B 61 -6,-1.6 -6,-3.4 -8,-0.0 2,-0.4 -0.967 42.7 -88.9-167.2 171.5 41.8 1.4 43.1 453 483 A V E -L 445 0B 28 -2,-0.3 2,-0.4 -8,-0.2 -8,-0.2 -0.731 30.8-170.8 -97.4 137.9 42.2 5.2 43.1 454 484 A E E -L 444 0B 56 -10,-2.4 -10,-2.5 -2,-0.4 2,-0.6 -0.970 21.5-127.7-124.0 144.8 44.5 7.0 40.7 455 485 A D E S-L 443 0B 100 -2,-0.4 -12,-0.2 1,-0.2 -13,-0.2 -0.829 82.7 -25.6 -95.2 124.2 45.4 10.7 40.9 456 486 A D S > S+ 0 0 51 -14,-2.0 3,-1.7 -2,-0.6 4,-0.4 0.875 73.7 175.1 43.8 55.6 44.9 12.6 37.6 457 487 A P T 3 S+ 0 0 36 0, 0.0 4,-0.3 0, 0.0 3,-0.2 0.783 77.4 46.5 -63.4 -24.4 45.4 9.5 35.4 458 488 A F T 3> S+ 0 0 15 -16,-0.2 4,-2.8 1,-0.2 5,-0.2 0.402 86.1 98.5 -95.3 3.2 44.5 11.4 32.3 459 489 A G H <> S+ 0 0 6 -3,-1.7 4,-3.0 1,-0.2 5,-0.2 0.869 76.9 50.8 -64.6 -43.9 46.8 14.4 33.0 460 490 A R H > S+ 0 0 193 -4,-0.4 4,-1.8 -3,-0.2 -1,-0.2 0.959 115.9 42.9 -61.5 -49.4 49.9 13.6 31.0 461 491 A E H > S+ 0 0 24 -4,-0.3 4,-1.3 1,-0.2 3,-0.3 0.962 114.1 51.2 -60.0 -51.8 47.8 13.0 27.9 462 492 A R H >X S+ 0 0 36 -4,-2.8 4,-2.4 1,-0.3 3,-0.5 0.892 109.0 51.2 -57.0 -40.2 45.7 16.1 28.5 463 493 A A H 3< S+ 0 0 71 -4,-3.0 -1,-0.3 1,-0.2 -2,-0.2 0.873 102.2 60.6 -68.8 -29.7 48.7 18.2 29.0 464 494 A A H 3< S+ 0 0 18 -4,-1.8 -1,-0.2 -3,-0.3 -2,-0.2 0.877 116.7 33.0 -60.7 -30.1 50.1 17.0 25.7 465 495 A W H << 0 0 27 -4,-1.3 -2,-0.2 -3,-0.5 -1,-0.2 0.860 360.0 360.0 -90.7 -41.5 47.1 18.4 24.0 466 496 A Q < 0 0 143 -4,-2.4 -3,-0.2 -5,-0.2 -2,-0.2 0.612 360.0 360.0-108.7 360.0 46.2 21.5 26.0