==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=9-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 17-SEP-97 1OHJ . COMPND 2 MOLECULE: DIHYDROFOLATE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR V.CODY,N.GALITSKY,J.R.LUFT,W.PANGBORN . 186 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10391.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 123 66.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 30 16.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 21 11.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 12.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 18 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 26 14.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A V 0 0 77 0, 0.0 2,-0.3 0, 0.0 100,-0.1 0.000 360.0 360.0 360.0 -98.8 9.8 14.3 31.0 2 2 A G + 0 0 60 109,-0.1 2,-0.2 2,-0.0 109,-0.2 -0.622 360.0 15.2 98.7-142.7 6.6 15.3 29.1 3 3 A S E -a 111 0A 31 107,-0.6 109,-3.4 -2,-0.3 2,-0.5 -0.557 49.8-153.4 -76.2 131.4 5.9 16.4 25.5 4 4 A L E +a 112 0A 23 126,-0.2 128,-1.2 -2,-0.2 2,-0.3 -0.909 22.9 164.3-123.3 108.8 8.3 16.2 22.4 5 5 A N E -ab 113 132A 2 107,-2.7 109,-3.5 -2,-0.5 2,-0.4 -0.862 23.8-153.5-121.8 146.7 7.9 18.7 19.5 6 6 A C E -ab 114 133A 2 126,-2.2 128,-2.3 -2,-0.3 2,-0.4 -0.978 10.0-162.2-118.6 131.3 10.1 19.7 16.5 7 7 A I E + b 0 134A 7 107,-1.5 2,-0.3 -2,-0.4 128,-0.2 -0.995 16.6 168.9-124.4 123.3 9.7 23.2 14.9 8 8 A V E - b 0 135A 10 126,-2.5 128,-2.4 -2,-0.4 2,-0.4 -0.876 27.2-153.1-126.8 158.5 11.1 23.8 11.4 9 9 A A E - b 0 136A 17 -2,-0.3 2,-0.3 126,-0.2 128,-0.2 -0.966 30.3-175.3-131.9 111.4 10.8 26.7 8.8 10 10 A V E - b 0 137A 0 126,-2.4 128,-2.4 -2,-0.4 6,-0.2 -0.934 23.8-124.8-123.8 139.7 11.4 25.2 5.3 11 11 A S > - 0 0 2 4,-2.2 3,-2.5 -2,-0.3 130,-0.2 -0.280 43.5 -97.4 -69.6 162.3 11.6 26.6 1.6 12 12 A Q T 3 S+ 0 0 132 128,-5.9 129,-0.2 1,-0.3 -1,-0.1 0.833 128.7 52.1 -52.4 -31.9 9.3 25.2 -1.1 13 13 A N T 3 S- 0 0 53 127,-0.4 -1,-0.3 129,-0.1 -2,-0.1 0.002 124.5-102.3 -94.0 26.2 12.2 23.0 -2.0 14 14 A M S < S+ 0 0 46 -3,-2.5 134,-2.1 1,-0.2 2,-0.4 0.543 70.7 149.7 64.8 13.9 12.7 21.6 1.5 15 15 A G E +I 147 0B 0 132,-0.2 -4,-2.2 127,-0.2 132,-0.3 -0.665 19.6 171.1 -82.5 129.7 15.8 23.8 2.2 16 16 A I E + 0 0 24 130,-1.9 2,-0.3 -2,-0.4 131,-0.2 0.631 60.8 14.0-106.7 -24.7 16.4 24.8 5.8 17 17 A G E -I 146 0B 8 129,-1.6 128,-2.4 5,-0.2 129,-0.9 -0.977 45.0-170.9-152.5 167.4 19.9 26.5 5.7 18 18 A K S S- 0 0 61 3,-4.0 125,-0.0 -2,-0.3 126,-0.0 -0.742 77.4 -4.8-164.0 113.1 22.7 27.9 3.6 19 19 A N S S- 0 0 131 -2,-0.2 3,-0.1 1,-0.2 125,-0.0 0.802 129.7 -51.1 73.2 36.8 26.2 29.0 4.8 20 20 A G S S+ 0 0 49 1,-0.3 2,-0.3 0, 0.0 -1,-0.2 0.829 129.9 90.4 68.0 28.5 25.7 28.3 8.5 21 21 A D S S- 0 0 92 2,-0.0 -3,-4.0 0, 0.0 -1,-0.3 -0.925 87.4 -84.3-151.9 176.7 22.6 30.5 7.8 22 22 A L - 0 0 66 -2,-0.3 -5,-0.2 -5,-0.3 -6,-0.1 -0.664 32.6-140.6 -83.1 136.5 19.1 30.9 6.8 23 23 A P S S+ 0 0 14 0, 0.0 120,-0.3 0, 0.0 -1,-0.1 0.690 79.0 54.3 -77.4 -22.5 18.4 31.0 3.1 24 24 A W S S- 0 0 12 1,-0.1 -2,-0.1 118,-0.1 3,-0.1 -0.670 97.9 -85.0-110.9 160.9 15.7 33.8 3.1 25 25 A P - 0 0 64 0, 0.0 -1,-0.1 0, 0.0 2,-0.0 -0.355 67.7 -77.6 -64.4 146.4 15.7 37.4 4.5 26 26 A P - 0 0 68 0, 0.0 2,-0.7 0, 0.0 0, 0.0 -0.260 39.8-157.8 -51.4 126.5 14.7 37.5 8.2 27 27 A L >> - 0 0 0 1,-0.1 4,-2.0 -3,-0.1 3,-1.3 -0.921 2.9-165.8-111.4 101.0 11.0 37.1 8.9 28 28 A R H 3> S+ 0 0 149 -2,-0.7 4,-1.4 1,-0.3 5,-0.2 0.812 84.7 55.4 -56.4 -42.7 10.3 38.7 12.4 29 29 A N H 34 S+ 0 0 76 2,-0.3 -1,-0.3 1,-0.2 4,-0.0 0.606 108.8 48.3 -68.6 -18.3 6.9 37.2 12.9 30 30 A E H X> S+ 0 0 19 -3,-1.3 4,-4.0 2,-0.2 3,-1.3 0.873 113.2 47.5 -80.8 -50.3 8.2 33.7 12.3 31 31 A F H 3X S+ 0 0 97 -4,-2.0 4,-1.0 1,-0.3 -2,-0.3 0.735 112.3 50.2 -62.8 -25.1 11.0 34.5 14.8 32 32 A R H 3X S+ 0 0 144 -4,-1.4 4,-0.7 2,-0.2 -1,-0.3 0.474 114.5 45.0 -89.6 -7.2 8.3 35.9 17.1 33 33 A Y H <> S+ 0 0 7 -3,-1.3 4,-2.8 -5,-0.2 -2,-0.2 0.835 110.0 51.3 -98.9 -44.1 6.3 32.6 16.6 34 34 A F H X S+ 0 0 45 -4,-4.0 4,-2.1 1,-0.2 -3,-0.2 0.918 114.5 48.0 -58.3 -46.8 9.3 30.3 17.0 35 35 A Q H X S+ 0 0 99 -4,-1.0 4,-1.2 -5,-0.3 -1,-0.2 0.822 112.9 44.7 -57.5 -46.3 9.9 32.3 20.2 36 36 A R H X S+ 0 0 110 -4,-0.7 4,-2.5 2,-0.2 3,-0.2 0.938 113.9 49.2 -72.1 -52.8 6.3 32.1 21.6 37 37 A M H < S+ 0 0 20 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.859 114.2 45.2 -57.7 -42.7 5.9 28.4 20.8 38 38 A T H < S+ 0 0 0 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.784 117.4 44.6 -69.8 -31.3 9.2 27.4 22.4 39 39 A T H < S+ 0 0 51 -4,-1.2 2,-0.6 -3,-0.2 9,-0.2 0.819 87.3 100.2 -81.7 -42.1 8.6 29.5 25.5 40 40 A T < - 0 0 83 -4,-2.5 2,-0.2 -5,-0.1 71,-0.1 -0.362 53.1-170.9 -68.9 112.9 4.9 28.7 26.2 41 41 A S - 0 0 29 -2,-0.6 7,-0.1 5,-0.2 4,-0.1 -0.632 19.1-142.1 -93.7 145.7 4.6 26.1 28.9 42 42 A S S S+ 0 0 78 -2,-0.2 -1,-0.2 1,-0.1 3,-0.1 0.929 84.5 48.3 -74.8 -85.0 1.3 24.4 29.8 43 43 A V S > S- 0 0 63 1,-0.1 3,-1.2 4,-0.1 -1,-0.1 -0.362 99.3-103.2 -58.3 132.8 1.4 24.1 33.6 44 44 A E T 3 S+ 0 0 178 1,-0.2 -1,-0.1 -2,-0.1 3,-0.1 -0.291 102.4 23.2 -57.8 134.0 2.4 27.4 35.5 45 45 A G T 3 S+ 0 0 88 1,-0.3 -1,-0.2 -3,-0.1 2,-0.1 -0.007 94.3 109.7 97.9 -29.0 6.0 27.4 36.8 46 46 A K < - 0 0 56 -3,-1.2 -1,-0.3 63,-0.1 2,-0.3 -0.450 54.8-147.6 -80.4 154.3 7.5 24.9 34.4 47 47 A Q E -c 109 0A 78 61,-2.2 63,-2.3 -2,-0.1 2,-0.4 -0.736 17.2-109.2-116.4 167.7 9.9 25.9 31.7 48 48 A N E - d 0 70A 0 21,-0.7 23,-2.7 -2,-0.3 2,-0.5 -0.812 20.9-141.3-101.0 141.7 10.5 24.5 28.2 49 49 A L E -cd 112 71A 4 62,-2.4 64,-2.3 -2,-0.4 2,-0.4 -0.916 17.0-166.9-104.4 120.4 13.7 22.6 27.3 50 50 A V E -cd 113 72A 0 21,-2.9 23,-2.4 -2,-0.5 2,-0.4 -0.920 1.2-162.2-112.8 129.5 15.1 23.3 23.8 51 51 A I E +cd 114 73A 0 62,-2.0 64,-1.7 -2,-0.4 65,-0.5 -0.965 15.5 166.1-118.0 127.6 17.7 21.1 22.2 52 52 A M E -cd 116 74A 0 21,-1.9 23,-2.5 -2,-0.4 65,-0.3 -0.939 35.4-108.5-140.4 159.6 19.9 22.1 19.2 53 53 A G > - 0 0 16 63,-1.0 4,-1.3 -2,-0.3 23,-0.1 -0.102 44.4-100.4 -73.3 175.9 23.0 21.0 17.4 54 54 A K H > S+ 0 0 65 21,-0.2 4,-2.3 2,-0.2 5,-0.1 0.898 118.6 49.0 -69.0 -50.8 26.2 23.0 17.7 55 55 A K H 4 S+ 0 0 135 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.916 109.6 54.6 -60.8 -37.6 26.1 25.0 14.5 56 56 A T H >4 S+ 0 0 37 1,-0.2 3,-1.8 2,-0.2 4,-0.2 0.927 107.0 51.6 -60.2 -46.2 22.5 25.9 15.1 57 57 A W H >< S+ 0 0 0 -4,-1.3 3,-1.5 1,-0.3 -2,-0.2 0.920 107.7 49.4 -56.9 -55.1 23.5 27.3 18.6 58 58 A F T 3< S+ 0 0 93 -4,-2.3 -1,-0.3 1,-0.2 4,-0.2 0.346 99.4 70.9 -69.8 4.2 26.2 29.6 17.3 59 59 A S T < S+ 0 0 55 -3,-1.8 -1,-0.2 -4,-0.2 -2,-0.2 0.410 75.7 91.2 -98.7 -0.6 23.8 30.9 14.6 60 60 A I S < S- 0 0 26 -3,-1.5 2,-0.1 -4,-0.2 5,-0.1 -0.792 103.0 -94.1 -86.3 132.4 21.8 32.8 17.1 61 61 A P > - 0 0 67 0, 0.0 3,-4.5 0, 0.0 4,-0.2 -0.314 35.6-116.3 -56.6 117.5 23.2 36.3 17.3 62 62 A E G > S+ 0 0 136 1,-0.3 3,-1.0 -4,-0.2 -2,-0.0 0.714 116.1 67.7 -22.1 -31.8 25.7 36.1 20.2 63 63 A K G 3 S+ 0 0 168 1,-0.3 -1,-0.3 0, 0.0 -3,-0.0 0.808 95.2 52.9 -55.0 -48.9 23.3 38.7 21.7 64 64 A N G < S+ 0 0 71 -3,-4.5 -1,-0.3 3,-0.1 4,-0.2 0.223 82.4 149.2 -87.4 3.7 20.4 36.2 22.0 65 65 A R < + 0 0 44 -3,-1.0 2,-0.2 -4,-0.2 21,-0.1 -0.889 58.8 24.2-113.4 136.6 22.0 33.4 23.9 66 66 A P S S- 0 0 44 0, 0.0 2,-1.0 0, 0.0 20,-0.1 0.557 96.2-115.6 -72.2 169.4 20.7 31.5 25.8 67 67 A L > - 0 0 11 -2,-0.2 3,-0.6 1,-0.1 -2,-0.1 -0.670 42.5-117.4 -74.4 102.4 17.2 31.8 24.5 68 68 A K T 3 S+ 0 0 187 -2,-1.0 3,-0.1 -4,-0.2 -1,-0.1 0.007 90.5 24.3 -44.1 141.4 15.5 33.4 27.6 69 69 A G T 3 S+ 0 0 27 1,-0.2 -21,-0.7 -22,-0.0 2,-0.3 0.743 110.0 75.9 66.7 33.1 12.7 31.4 29.3 70 70 A R E < S-d 48 0A 13 -3,-0.6 2,-0.5 -23,-0.2 -21,-0.2 -0.942 86.5-103.4-160.4 156.7 13.8 28.0 28.2 71 71 A I E -d 49 0A 13 -23,-2.7 -21,-2.9 -2,-0.3 2,-0.6 -0.796 34.4-142.8 -90.1 123.9 16.5 25.6 29.1 72 72 A N E +d 50 0A 0 -2,-0.5 15,-2.5 -23,-0.2 16,-1.5 -0.854 24.1 176.5 -93.1 112.5 19.3 25.7 26.4 73 73 A L E -de 51 88A 0 -23,-2.4 -21,-1.9 -2,-0.6 2,-0.4 -0.961 8.4-165.0-120.4 132.3 20.7 22.2 25.7 74 74 A V E -de 52 89A 0 14,-2.3 16,-2.1 -2,-0.4 2,-0.4 -0.961 10.0-143.4-128.3 132.9 23.4 21.7 23.0 75 75 A L E + e 0 90A 23 -23,-2.5 2,-0.3 -2,-0.4 -21,-0.2 -0.825 30.4 152.5 -98.6 142.9 24.6 18.4 21.4 76 76 A S - 0 0 13 14,-1.5 -2,-0.0 -2,-0.4 13,-0.0 -0.903 34.7-160.2-162.4 142.5 28.3 18.0 20.4 77 77 A R S S+ 0 0 217 -2,-0.3 14,-0.1 1,-0.0 15,-0.0 0.757 97.2 39.2 -91.6 -35.0 30.5 14.9 20.0 78 78 A E S S+ 0 0 139 13,-0.0 2,-0.2 2,-0.0 13,-0.1 0.600 89.2 83.9 -85.1 -39.8 33.6 17.1 20.3 79 79 A L - 0 0 43 1,-0.1 -3,-0.1 12,-0.0 10,-0.0 -0.522 50.9-163.8 -74.3 159.9 33.3 19.9 22.8 80 80 A K S S+ 0 0 195 1,-0.3 -1,-0.1 -2,-0.2 9,-0.1 0.345 74.0 42.7-121.9 -12.8 34.1 19.0 26.5 81 81 A E S S- 0 0 152 3,-0.0 -1,-0.3 0, 0.0 3,-0.1 -0.988 98.7 -97.3-137.8 129.6 32.6 22.0 28.3 82 82 A P - 0 0 56 0, 0.0 3,-0.1 0, 0.0 7,-0.1 -0.053 51.3 -92.4 -48.3 148.9 29.2 23.5 27.4 83 83 A P > - 0 0 13 0, 0.0 3,-1.1 0, 0.0 2,-0.6 -0.092 56.7 -75.3 -60.5 162.6 29.3 26.5 25.2 84 84 A Q T 3 S+ 0 0 187 1,-0.3 3,-0.1 -3,-0.1 -19,-0.1 -0.531 122.7 7.2 -66.8 106.7 29.4 30.0 26.7 85 85 A G T 3 S+ 0 0 37 -2,-0.6 -1,-0.3 1,-0.4 -13,-0.2 -0.001 96.8 119.6 107.4 -25.3 25.9 30.5 27.9 86 86 A A < - 0 0 15 -3,-1.1 -1,-0.4 1,-0.1 -13,-0.2 -0.262 51.5-152.0 -64.4 163.7 24.4 27.0 27.2 87 87 A H S S+ 0 0 95 -15,-2.5 2,-0.3 1,-0.4 -14,-0.2 0.670 76.5 20.9-109.6 -31.4 23.1 25.3 30.4 88 88 A F E -e 73 0A 69 -16,-1.5 -14,-2.3 2,-0.0 -1,-0.4 -0.987 58.3-166.3-138.4 145.1 23.6 21.6 29.3 89 89 A L E -e 74 0A 30 -2,-0.3 2,-0.3 -16,-0.2 -14,-0.2 -0.975 17.2-174.9-130.8 119.5 25.8 20.0 26.7 90 90 A S E -e 75 0A 18 -16,-2.1 -14,-1.5 -2,-0.4 3,-0.1 -0.839 27.0-141.9-122.7 154.2 25.0 16.4 25.7 91 91 A R S S+ 0 0 98 -2,-0.3 2,-0.3 -16,-0.2 -16,-0.1 0.697 84.2 20.3 -85.7 -20.3 26.8 13.9 23.5 92 92 A S S >> S- 0 0 45 1,-0.1 4,-1.1 -17,-0.0 3,-0.6 -0.943 74.0-118.5-146.2 157.3 23.8 12.2 22.0 93 93 A L H 3> S+ 0 0 4 -2,-0.3 4,-2.1 1,-0.2 3,-0.3 0.877 112.4 58.6 -58.6 -50.4 20.1 13.1 21.5 94 94 A D H 3> S+ 0 0 77 1,-0.3 4,-1.5 2,-0.2 -1,-0.2 0.538 103.3 51.1 -57.4 -22.2 19.1 10.1 23.6 95 95 A D H <> S+ 0 0 74 -3,-0.6 4,-1.4 2,-0.2 -1,-0.3 0.793 104.9 57.6 -85.9 -42.2 21.0 11.4 26.6 96 96 A A H >X S+ 0 0 0 -4,-1.1 4,-1.0 -3,-0.3 3,-0.7 0.962 113.0 39.8 -56.7 -52.1 19.3 14.7 26.2 97 97 A L H >X S+ 0 0 17 -4,-2.1 3,-1.4 1,-0.2 4,-0.7 0.947 111.8 56.3 -59.8 -50.8 15.9 12.9 26.5 98 98 A K H 3X S+ 0 0 94 -4,-1.5 4,-0.6 1,-0.3 -1,-0.2 0.703 101.2 62.1 -51.4 -24.4 17.4 10.6 29.3 99 99 A L H X< S+ 0 0 39 -4,-1.4 3,-0.7 -3,-0.7 -1,-0.3 0.893 99.1 52.1 -68.8 -45.3 18.2 13.9 31.0 100 100 A T H << S+ 0 0 3 -3,-1.4 -1,-0.2 -4,-1.0 -2,-0.2 0.543 98.5 64.9 -73.0 -11.8 14.5 14.9 31.2 101 101 A E H 3< S+ 0 0 111 -4,-0.7 -1,-0.2 -3,-0.2 -2,-0.2 0.768 77.4 107.8 -77.6 -30.6 13.6 11.6 32.9 102 102 A Q S XX S- 0 0 88 -3,-0.7 3,-4.2 -4,-0.6 4,-1.5 -0.313 78.9-131.3 -53.9 114.1 15.7 12.6 35.8 103 103 A P H 3> S+ 0 0 87 0, 0.0 4,-0.7 0, 0.0 -1,-0.2 0.632 107.6 62.1 -44.5 -14.4 13.4 13.4 38.7 104 104 A E H 34 S+ 0 0 151 1,-0.2 -2,-0.1 2,-0.2 -4,-0.1 0.532 116.7 28.7 -91.6 -7.7 15.4 16.7 39.1 105 105 A L H <> S+ 0 0 19 -3,-4.2 4,-1.0 -6,-0.2 -1,-0.2 0.325 106.2 80.9-127.3 -3.7 14.4 17.8 35.6 106 106 A A H < S+ 0 0 25 -4,-1.5 -2,-0.2 1,-0.2 -6,-0.1 0.857 100.3 35.9 -73.9 -38.4 11.2 15.8 35.9 107 107 A N T < S+ 0 0 133 -4,-0.7 -1,-0.2 -5,-0.2 -2,-0.1 0.544 118.6 48.5 -93.0 -10.6 9.5 18.6 37.9 108 108 A K T 4 S+ 0 0 92 -62,-0.1 -61,-2.2 2,-0.0 2,-0.3 0.653 98.3 70.2-108.9 -11.4 11.0 21.6 36.2 109 109 A V E < + c 0 47A 3 -4,-1.0 -61,-0.2 -63,-0.2 3,-0.1 -0.869 43.9 172.1-106.4 143.0 10.5 20.8 32.5 110 110 A D E + 0 0 19 -63,-2.3 -107,-0.6 1,-0.3 2,-0.3 0.702 63.6 11.8-106.4 -88.4 7.3 20.8 30.5 111 111 A M E -a 3 0A 40 -109,-0.2 -62,-2.4 -73,-0.1 2,-0.5 -0.661 60.7-143.2-100.0 145.6 7.8 20.5 26.7 112 112 A V E -ac 4 49A 5 -109,-3.4 -107,-2.7 -2,-0.3 2,-0.5 -0.914 14.5-164.3-109.2 134.9 10.8 19.6 24.8 113 113 A W E -ac 5 50A 3 -64,-2.3 -62,-2.0 -2,-0.5 2,-1.0 -0.994 14.0-150.7-119.5 125.0 11.3 21.3 21.5 114 114 A I E +ac 6 51A 0 -109,-3.5 -107,-1.5 -2,-0.5 -62,-0.2 -0.881 20.6 178.2 -92.1 101.8 13.8 19.9 19.0 115 115 A V E - 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