==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-MAR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CYTOKINE/SIGNALING PROTEIN 20-AUG-10 3OJ2 . COMPND 2 MOLECULE: HEPARIN-BINDING GROWTH FACTOR 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.BEENKEN,M.MOHAMMADI . 688 4 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 31664.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 416 60.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 22 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 232 33.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 12 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 10 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 64 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 70 10.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 18 6 4 10 2 8 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 6 2 0 4 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 19 A P 0 0 136 0, 0.0 3,-0.4 0, 0.0 401,-0.0 0.000 360.0 360.0 360.0 78.9 -3.5 17.0 -11.5 2 20 A P + 0 0 49 0, 0.0 401,-0.2 0, 0.0 378,-0.0 -0.275 360.0 39.1 -68.9 150.2 -0.4 15.0 -12.4 3 21 A G > + 0 0 18 399,-2.7 3,-0.6 4,-0.0 400,-0.1 0.694 61.3 133.8 87.9 20.8 1.8 15.7 -15.4 4 22 A N G > + 0 0 88 -3,-0.4 3,-1.6 398,-0.3 399,-0.1 0.805 66.2 68.3 -71.2 -27.3 1.8 19.5 -15.5 5 23 A Y G 3 S+ 0 0 15 1,-0.3 38,-0.3 397,-0.3 -1,-0.2 0.796 94.6 56.4 -62.2 -29.6 5.5 19.4 -16.0 6 24 A K G < S+ 0 0 92 -3,-0.6 -1,-0.3 36,-0.1 -2,-0.2 0.274 86.1 96.8 -90.6 15.0 5.1 18.0 -19.5 7 25 A K S < S- 0 0 94 -3,-1.6 36,-0.3 1,-0.1 34,-0.1 -0.740 86.7 -96.8 -98.7 149.8 2.8 20.7 -20.8 8 26 A P - 0 0 40 0, 0.0 2,-0.3 0, 0.0 34,-0.2 -0.240 49.0-172.5 -60.1 157.3 4.3 23.6 -22.8 9 27 A K B -A 41 0A 21 32,-2.9 32,-2.9 124,-0.1 2,-0.4 -0.969 26.7-120.2-149.8 163.2 5.1 26.8 -20.9 10 28 A L E -B 132 0A 6 122,-2.8 122,-2.9 -2,-0.3 2,-0.9 -0.876 24.9-138.4-104.1 137.3 6.2 30.3 -21.2 11 29 A L E -B 131 0A 2 -2,-0.4 9,-2.7 28,-0.4 2,-0.4 -0.862 22.3-158.4 -99.6 104.1 9.3 31.2 -19.5 12 30 A Y E -BC 130 19A 0 118,-2.7 118,-2.8 -2,-0.9 2,-0.6 -0.680 3.8-148.6 -85.4 132.1 8.7 34.6 -17.9 13 31 A C E > -B 129 0A 0 5,-2.8 4,-1.8 -2,-0.4 3,-0.5 -0.890 3.2-156.9-103.3 121.6 11.7 36.8 -17.0 14 32 A S T 4 S+ 0 0 13 114,-2.1 112,-0.2 -2,-0.6 -1,-0.1 0.706 80.2 80.1 -69.2 -20.5 11.2 39.1 -14.0 15 33 A N T 4 S- 0 0 19 110,-0.9 -1,-0.2 113,-0.4 111,-0.2 0.914 123.5 -9.3 -54.5 -50.3 13.9 41.5 -15.1 16 34 A G T 4 S- 0 0 3 -3,-0.5 271,-0.3 93,-0.2 -1,-0.2 0.479 98.4-104.3-127.0 -10.8 11.7 43.4 -17.6 17 35 A G S < S+ 0 0 1 -4,-1.8 271,-0.3 1,-0.2 -3,-0.2 0.672 70.2 144.1 93.6 19.4 8.6 41.2 -17.8 18 36 A H - 0 0 7 -5,-0.5 -5,-2.8 12,-0.1 2,-0.5 -0.475 48.8-125.2 -90.4 163.8 9.3 39.6 -21.2 19 37 A F E -CD 12 31A 2 12,-1.8 12,-1.7 -7,-0.2 -7,-0.2 -0.913 33.8-110.1-106.2 130.7 8.6 36.0 -22.3 20 38 A L E - D 0 30A 1 -9,-2.7 2,-0.4 -2,-0.5 -9,-0.3 -0.369 45.0-173.3 -60.2 134.0 11.5 34.1 -23.6 21 39 A R E - D 0 29A 0 8,-2.6 8,-1.6 -11,-0.1 2,-0.5 -0.997 23.0-145.3-139.9 141.5 11.1 33.6 -27.4 22 40 A I E - D 0 28A 1 16,-2.1 6,-0.2 -2,-0.4 5,-0.1 -0.901 18.6-149.3-104.7 123.6 12.9 31.7 -30.1 23 41 A L > - 0 0 37 4,-2.5 3,-2.5 -2,-0.5 49,-0.2 -0.790 20.6-125.0 -96.7 133.3 13.1 33.4 -33.6 24 42 A P T 3 S+ 0 0 77 0, 0.0 -1,-0.1 0, 0.0 4,-0.0 0.800 110.6 66.6 -41.3 -36.0 13.1 31.3 -36.8 25 43 A D T 3 S- 0 0 113 1,-0.1 2,-0.1 2,-0.1 3,-0.1 0.269 120.4-109.9 -73.9 14.9 16.3 33.2 -37.7 26 44 A G S < S+ 0 0 19 -3,-2.5 46,-2.4 1,-0.2 -1,-0.1 0.033 82.1 120.5 83.1 -30.3 18.0 31.5 -34.8 27 45 A T B -E 71 0A 79 44,-0.2 -4,-2.5 -2,-0.1 2,-0.4 -0.323 50.6-147.9 -68.4 151.9 18.3 34.6 -32.7 28 46 A V E +D 22 0A 11 42,-0.8 86,-0.5 -6,-0.2 2,-0.2 -0.980 27.6 145.6-127.3 135.7 16.6 34.7 -29.3 29 47 A D E -DF 21 113A 48 -8,-1.6 -8,-2.6 -2,-0.4 2,-0.4 -0.672 40.5 -98.5-143.2-162.9 15.0 37.6 -27.4 30 48 A G E -D 20 0A 8 82,-1.4 2,-0.4 -10,-0.2 -10,-0.2 -0.989 28.2-174.5-134.0 141.9 12.2 38.5 -25.1 31 49 A T E -D 19 0A 27 -12,-1.7 -12,-1.8 -2,-0.4 -14,-0.0 -0.999 29.7-148.4-139.6 137.4 8.8 40.0 -25.8 32 50 A R S S+ 0 0 46 -2,-0.4 2,-1.2 -14,-0.2 -1,-0.1 0.535 74.1 112.2 -76.5 -4.3 6.0 41.2 -23.6 33 51 A D > - 0 0 79 1,-0.2 3,-0.9 -14,-0.1 -2,-0.1 -0.578 48.0-175.8 -73.9 96.6 3.8 40.1 -26.5 34 52 A R T 3 S+ 0 0 71 -2,-1.2 -1,-0.2 1,-0.2 5,-0.1 0.449 80.8 59.7 -74.6 -1.4 2.0 37.1 -25.0 35 53 A S T 3 S+ 0 0 98 3,-0.0 -1,-0.2 4,-0.0 4,-0.1 0.670 73.8 122.5 -96.0 -23.1 0.4 36.3 -28.4 36 54 A D X - 0 0 37 -3,-0.9 3,-0.6 1,-0.2 4,-0.1 -0.104 60.6-144.0 -40.2 127.6 3.8 35.9 -30.0 37 55 A Q T 3 S+ 0 0 52 1,-0.2 3,-0.4 2,-0.1 -1,-0.2 0.546 89.3 67.2 -79.4 -7.5 3.7 32.3 -31.5 38 56 A H T 3 S+ 0 0 37 1,-0.2 -16,-2.1 19,-0.1 -1,-0.2 -0.141 82.5 72.7-106.8 38.2 7.4 31.7 -30.7 39 57 A I < + 0 0 2 -3,-0.6 2,-0.8 -18,-0.2 -28,-0.4 0.463 61.3 107.3-124.3 -9.2 7.3 31.7 -26.9 40 58 A Q - 0 0 76 -3,-0.4 16,-3.1 -4,-0.1 17,-0.5 -0.645 55.9-168.4 -75.5 109.0 5.5 28.3 -26.2 41 59 A L E -AG 9 55A 0 -32,-2.9 -32,-2.9 -2,-0.8 2,-0.6 -0.816 20.3-150.2-109.1 142.9 8.3 26.2 -24.9 42 60 A Q E - G 0 54A 49 12,-3.4 12,-2.8 -2,-0.4 2,-0.3 -0.940 17.9-162.8-110.6 113.8 8.5 22.5 -24.3 43 61 A L E + G 0 53A 6 -2,-0.6 2,-0.3 -36,-0.3 10,-0.2 -0.751 12.4 172.1 -97.9 143.7 10.9 21.5 -21.4 44 62 A S E - G 0 52A 39 8,-1.6 8,-2.4 -2,-0.3 2,-0.9 -0.988 32.5-125.3-151.3 141.4 12.2 18.0 -20.9 45 63 A A E - G 0 51A 4 363,-0.6 6,-0.3 -2,-0.3 365,-0.2 -0.782 21.9-179.8 -92.5 102.9 14.8 16.5 -18.5 46 64 A E E S+ 0 0 38 4,-1.4 2,-0.3 -2,-0.9 -1,-0.2 0.790 79.6 2.0 -69.9 -29.0 17.4 14.7 -20.6 47 65 A S E > S- G 0 50A 51 3,-1.5 3,-2.3 -3,-0.1 2,-0.2 -0.881 111.7 -58.6-145.5 171.3 19.2 13.8 -17.3 48 66 A V T 3 S- 0 0 65 1,-0.3 418,-0.1 -2,-0.3 3,-0.1 -0.383 126.6 -4.6 -59.3 122.1 18.4 14.5 -13.7 49 67 A G T 3 S+ 0 0 6 358,-0.5 35,-1.0 416,-0.3 2,-0.5 0.595 112.2 112.2 69.7 9.8 18.2 18.2 -13.3 50 68 A E E < -GH 47 83A 34 -3,-2.3 -3,-1.5 33,-0.2 -4,-1.4 -0.966 46.9-173.7-120.6 121.9 19.3 18.7 -16.9 51 69 A V E -GH 45 82A 1 31,-3.0 31,-2.3 -2,-0.5 2,-0.3 -0.804 26.3-148.1-123.2 156.6 16.9 20.1 -19.5 52 70 A Y E -G 44 0A 18 -8,-2.4 -8,-1.6 -2,-0.3 2,-0.5 -0.813 18.9-151.5-105.1 150.6 16.3 20.9 -23.2 53 71 A I E -G 43 0A 0 27,-0.4 9,-3.1 9,-0.3 2,-0.4 -0.953 20.4-176.3-128.9 107.2 14.1 23.9 -23.9 54 72 A K E -GI 42 61A 71 -12,-2.8 -12,-3.4 -2,-0.5 2,-0.3 -0.915 27.7-123.2-117.4 132.9 12.3 23.5 -27.3 55 73 A S E > -G 41 0A 1 5,-2.2 4,-1.9 -2,-0.4 -14,-0.2 -0.484 13.3-152.2 -66.1 123.3 9.9 25.8 -29.2 56 74 A T T 4 S+ 0 0 57 -16,-3.1 -1,-0.2 -2,-0.3 -15,-0.1 0.684 94.4 51.4 -71.6 -12.3 6.6 24.1 -29.8 57 75 A E T 4 S+ 0 0 115 -17,-0.5 -1,-0.2 -20,-0.1 -19,-0.1 0.928 127.5 12.7 -88.4 -50.8 6.3 26.2 -32.9 58 76 A T T 4 S- 0 0 44 2,-0.1 -2,-0.2 -36,-0.1 3,-0.1 0.669 90.1-126.7-102.1 -20.1 9.6 25.7 -34.8 59 77 A G < + 0 0 23 -4,-1.9 2,-0.1 1,-0.3 -3,-0.1 0.599 58.2 146.4 83.1 10.3 11.1 22.7 -33.0 60 78 A Q - 0 0 4 -5,-0.1 -5,-2.2 -38,-0.1 2,-0.5 -0.455 45.3-128.5 -78.9 155.7 14.3 24.6 -32.3 61 79 A Y E -IJ 54 73A 24 12,-3.3 12,-1.0 -7,-0.2 -7,-0.2 -0.922 19.8-119.0-110.0 126.1 16.3 24.0 -29.1 62 80 A L E + J 0 72A 1 -9,-3.1 -9,-0.3 -2,-0.5 2,-0.3 -0.275 46.8 168.7 -56.6 145.0 17.4 26.9 -26.9 63 81 A A E - J 0 71A 0 8,-1.2 8,-2.0 -11,-0.1 2,-0.4 -0.990 32.6-139.4-158.2 162.4 21.2 27.0 -26.7 64 82 A M E - J 0 70A 0 15,-1.8 6,-0.2 -2,-0.3 17,-0.1 -0.994 22.2-145.8-129.5 127.6 24.3 29.0 -25.7 65 83 A D - 0 0 29 4,-1.9 3,-0.3 -2,-0.4 5,-0.0 -0.201 41.3 -79.5 -86.9 180.0 27.5 29.2 -27.7 66 84 A T S S+ 0 0 97 1,-0.2 -1,-0.1 2,-0.1 -2,-0.0 0.573 131.0 44.1 -53.8 -11.1 31.1 29.5 -26.6 67 85 A D S S- 0 0 114 2,-0.1 -1,-0.2 50,-0.0 -3,-0.0 0.790 120.5 -98.8-102.1 -41.3 30.6 33.2 -26.0 68 86 A G S S+ 0 0 0 1,-0.3 49,-1.5 -3,-0.3 2,-0.3 0.438 71.0 143.3 129.9 11.8 27.3 33.2 -24.2 69 87 A L - 0 0 72 47,-0.2 -4,-1.9 48,-0.1 2,-0.7 -0.653 48.8-127.7 -85.7 135.2 24.9 34.1 -27.0 70 88 A L E + J 0 64A 11 -2,-0.3 -42,-0.8 -6,-0.2 2,-0.3 -0.714 36.5 170.7 -85.7 112.9 21.5 32.5 -27.0 71 89 A Y E -EJ 27 63A 56 -8,-2.0 -8,-1.2 -2,-0.7 2,-0.9 -0.853 36.6-124.7-121.3 158.1 20.7 30.8 -30.3 72 90 A G E - J 0 62A 6 -46,-2.4 -10,-0.2 -2,-0.3 -46,-0.1 -0.610 30.7-156.0-103.1 75.4 17.9 28.4 -31.4 73 91 A S E - J 0 61A 17 -12,-1.0 -12,-3.3 -2,-0.9 -47,-0.0 -0.119 13.2-144.8 -50.2 136.2 19.6 25.3 -32.8 74 92 A Q S S+ 0 0 132 -14,-0.2 -1,-0.1 1,-0.1 -2,-0.0 0.752 87.8 41.8 -75.0 -25.4 17.6 23.3 -35.3 75 93 A T S S- 0 0 92 -14,-0.1 2,-0.4 -15,-0.0 -14,-0.1 -0.943 96.5-103.0-124.7 145.2 19.2 20.1 -34.0 76 94 A P + 0 0 56 0, 0.0 2,-0.2 0, 0.0 -13,-0.1 -0.526 51.9 158.7 -71.0 121.1 19.8 19.1 -30.3 77 95 A N > - 0 0 42 -2,-0.4 3,-1.6 -16,-0.1 4,-0.2 -0.691 57.6 -84.4-130.0-176.2 23.5 19.4 -29.3 78 96 A E T 3 S+ 0 0 140 1,-0.3 20,-0.4 -2,-0.2 3,-0.3 0.547 121.9 63.9 -72.2 -5.8 25.5 19.8 -26.1 79 97 A E T 3 S+ 0 0 33 1,-0.2 -15,-1.8 18,-0.1 -1,-0.3 0.501 92.2 65.8 -92.7 -4.8 25.0 23.5 -26.1 80 98 A C S < S+ 0 0 0 -3,-1.6 2,-0.5 -17,-0.2 -27,-0.4 0.465 78.9 97.7 -93.6 -5.1 21.2 23.0 -25.6 81 99 A L + 0 0 19 -3,-0.3 16,-2.3 -4,-0.2 17,-0.6 -0.758 49.8 179.1 -93.1 130.3 21.4 21.4 -22.2 82 100 A F E -HK 51 96A 0 -31,-2.3 -31,-3.0 -2,-0.5 2,-0.8 -0.903 31.4-121.2-127.4 153.8 20.8 23.6 -19.1 83 101 A L E -HK 50 95A 33 12,-3.0 12,-1.8 -2,-0.3 2,-0.5 -0.859 29.2-153.4 -96.7 110.2 20.7 23.0 -15.4 84 102 A E E + K 0 94A 7 -35,-1.0 2,-0.3 -2,-0.8 383,-0.2 -0.751 23.7 165.2 -88.7 123.2 17.3 24.0 -14.1 85 103 A R E - 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