==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=9-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 20-MAR-03 1OSS . COMPND 2 MOLECULE: TRYPSIN; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES GRISEUS; . AUTHOR M.J.PAGE,S.L.WONG,J.HEWITT,N.C.STRYNADKA,R.T.MACGILLIVRAY . 223 1 3 3 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9454.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 141 63.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 3 1.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 71 31.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 7.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 25 11.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 18 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 5 1 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A V > 0 0 1 0, 0.0 3,-0.8 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 123.2 45.2 -29.1 68.2 2 17 A V B 3 +A 166 0A 22 164,-3.1 164,-1.9 1,-0.2 117,-0.1 -0.730 360.0 11.9 -85.0 135.5 45.7 -31.8 65.6 3 18 A G T 3 S+ 0 0 49 115,-0.5 -1,-0.2 -2,-0.4 2,-0.1 0.704 100.0 133.5 72.2 20.5 48.5 -34.3 66.5 4 19 A G < - 0 0 26 -3,-0.8 2,-0.3 162,-0.1 127,-0.2 -0.360 44.3-142.7 -95.5 178.4 48.6 -33.0 70.1 5 20 A T E -B 130 0B 89 125,-2.6 125,-3.0 -2,-0.1 2,-0.1 -0.906 37.7 -74.4-136.4 162.3 48.6 -35.0 73.4 6 21 A R E -B 129 0B 152 -2,-0.3 2,-0.2 123,-0.2 123,-0.2 -0.382 42.9-136.1 -65.5 132.7 47.0 -34.3 76.8 7 22 A A - 0 0 8 121,-2.5 2,-0.1 -2,-0.1 121,-0.1 -0.606 26.5-110.9 -83.0 146.1 48.6 -31.6 78.8 8 23 A A > - 0 0 58 -2,-0.2 3,-2.1 1,-0.1 4,-0.5 -0.463 38.6 -93.0 -77.3 150.7 49.0 -32.4 82.5 9 24 A Q T 3 S+ 0 0 113 1,-0.3 -1,-0.1 2,-0.1 45,-0.1 -0.450 115.7 14.8 -61.2 131.0 47.0 -30.5 85.1 10 25 A G T 3 S+ 0 0 47 -2,-0.1 -1,-0.3 2,-0.1 4,-0.1 0.318 94.8 111.8 85.8 -8.3 49.0 -27.6 86.2 11 26 A E S < S+ 0 0 66 -3,-2.1 -2,-0.1 1,-0.3 3,-0.1 0.934 93.8 14.6 -63.7 -49.3 51.5 -27.8 83.3 12 27 A F S > S+ 0 0 12 -4,-0.5 3,-1.6 1,-0.1 -1,-0.3 -0.683 74.6 168.3-127.9 74.5 50.4 -24.6 81.6 13 28 A P T 3 + 0 0 29 0, 0.0 40,-0.4 0, 0.0 -1,-0.1 0.589 68.6 70.1 -64.8 -14.1 48.4 -22.8 84.3 14 29 A F T 3 S+ 0 0 7 82,-0.1 12,-1.9 -3,-0.1 2,-0.2 0.548 77.1 109.3 -81.0 -7.8 48.3 -19.5 82.4 15 30 A M E < -J 25 0C 7 -3,-1.6 38,-0.5 10,-0.2 2,-0.3 -0.454 46.3-176.2 -72.4 137.4 45.9 -21.1 79.8 16 31 A V E -J 24 0C 0 8,-2.5 8,-1.2 -2,-0.2 2,-0.4 -0.978 19.9-137.5-132.9 148.3 42.3 -20.0 79.7 17 32 A R E -JK 23 51C 27 34,-2.2 34,-2.7 -2,-0.3 2,-0.4 -0.878 20.5-147.7-102.2 136.5 39.4 -21.2 77.6 18 33 A L E >> -JK 22 50C 1 4,-2.8 3,-2.0 -2,-0.4 4,-1.2 -0.867 17.9-122.4-109.0 142.0 37.1 -18.6 76.1 19 34 A S T 34 S+ 0 0 72 30,-2.1 31,-0.1 -2,-0.4 -1,-0.1 0.675 105.5 61.8 -53.6 -25.9 33.4 -19.0 75.5 20 35 A M T 34 S- 0 0 75 29,-0.2 -1,-0.3 18,-0.1 150,-0.1 0.384 127.8 -88.6 -85.9 8.8 33.4 -18.3 71.8 21 41 A G T <4 S+ 0 0 21 -3,-2.0 151,-0.3 1,-0.3 2,-0.3 0.919 89.7 117.6 86.5 50.0 35.7 -21.2 71.1 22 42 A a E < -J 18 0C 6 -4,-1.2 -4,-2.8 149,-0.1 -1,-0.3 -0.896 54.2-130.5-138.7 167.9 39.1 -19.6 71.5 23 43 A G E +J 17 0C 0 149,-3.3 12,-0.4 -2,-0.3 2,-0.3 -0.618 26.3 177.0-110.5 176.2 42.1 -20.0 73.8 24 44 A G E -J 16 0C 0 -8,-1.2 -8,-2.5 -2,-0.2 2,-0.3 -0.969 22.1-125.0-169.8 166.2 43.9 -17.3 75.7 25 45 A A E -JL 15 33C 0 8,-2.3 8,-2.9 -2,-0.3 2,-1.2 -0.928 30.1-109.6-123.9 149.7 46.7 -16.7 78.1 26 46 A L E + L 0 32C 0 -12,-1.9 71,-2.3 -2,-0.3 6,-0.2 -0.671 35.5 173.1 -78.8 100.5 46.7 -14.8 81.4 27 47 A Y E S- 0 0 60 4,-1.9 2,-0.3 -2,-1.2 -1,-0.2 0.840 83.3 -3.0 -73.3 -33.9 48.7 -11.7 80.6 28 48 A A E > S- L 0 31C 26 3,-1.8 3,-1.5 -3,-0.2 -1,-0.3 -0.900 92.0 -95.6-145.1 163.7 47.7 -10.5 84.1 29 49 A Q T 3 S+ 0 0 70 -2,-0.3 63,-2.9 1,-0.3 61,-0.1 0.819 127.7 29.6 -58.4 -26.7 45.4 -12.4 86.5 30 50 A D T 3 S+ 0 0 47 61,-0.3 58,-3.0 1,-0.1 2,-0.4 0.114 111.3 73.7-119.7 21.9 42.4 -10.3 85.3 31 51 A I E < -LM 28 87C 10 -3,-1.5 -4,-1.9 56,-0.2 -3,-1.8 -0.955 62.6-157.9-138.5 117.4 43.5 -9.6 81.7 32 52 A V E -LM 26 86C 0 54,-2.9 54,-2.0 -2,-0.4 2,-0.6 -0.801 6.6-149.5 -97.6 131.7 43.4 -12.3 79.0 33 53 A L E +LM 25 85C 0 -8,-2.9 -8,-2.3 -2,-0.4 52,-0.2 -0.902 39.1 140.6 -98.4 124.0 45.6 -12.0 75.8 34 54 A T E - M 0 84C 0 50,-2.9 50,-2.1 -2,-0.6 2,-0.2 -0.701 52.5 -60.4-144.0-166.6 43.8 -13.6 72.9 35 55 A A > - 0 0 0 -12,-0.4 3,-1.2 48,-0.3 48,-0.3 -0.584 32.9-132.3 -89.5 149.3 43.3 -13.1 69.2 36 56 A A G > S+ 0 0 0 1,-0.2 3,-1.5 -2,-0.2 -1,-0.1 0.857 107.2 60.7 -65.6 -32.5 41.5 -10.0 67.7 37 57 A H G 3 S+ 0 0 74 1,-0.3 -1,-0.2 3,-0.0 45,-0.0 0.572 90.1 70.5 -74.4 -3.6 39.4 -12.3 65.5 38 58 A a G < S+ 0 0 11 -3,-1.2 2,-0.3 -15,-0.1 -1,-0.3 0.615 102.4 46.7 -83.3 -13.8 38.0 -14.0 68.7 39 59 A V S < S- 0 0 16 -3,-1.5 3,-0.1 -4,-0.3 0, 0.0 -0.823 75.7-133.5-123.8 165.1 36.0 -10.8 69.5 40 60 A S S S- 0 0 122 1,-0.3 2,-0.3 -2,-0.3 -1,-0.1 0.669 73.6 -49.0 -93.5 -17.3 33.8 -8.4 67.5 41 60AA G - 0 0 22 2,-0.1 -1,-0.3 -5,-0.0 2,-0.2 -0.964 67.6 -60.6 167.4 179.8 35.2 -5.2 68.7 42 60BA S S S+ 0 0 77 -2,-0.3 2,-0.2 30,-0.1 29,-0.2 -0.551 72.3 78.6 -88.6 153.8 36.3 -3.1 71.7 43 60CA G E S-N 70 0C 35 27,-2.6 27,-2.6 -2,-0.2 2,-0.1 -0.780 83.3 -34.1 141.1 175.1 34.0 -1.9 74.5 44 60DA N E +N 69 0C 138 25,-0.2 25,-0.3 -2,-0.2 2,-0.3 -0.456 63.8 167.7 -63.9 137.9 32.3 -2.9 77.7 45 61 A N + 0 0 37 23,-2.1 3,-0.1 -2,-0.1 -2,-0.1 -0.883 25.3 169.7-159.9 119.5 31.3 -6.5 77.4 46 62 A T + 0 0 97 -2,-0.3 22,-0.1 1,-0.1 -1,-0.1 0.149 65.1 86.4-118.0 17.8 30.1 -8.9 80.1 47 63 A S + 0 0 82 19,-0.1 2,-0.4 2,-0.0 -1,-0.1 0.494 67.5 91.1 -97.0 -5.7 29.0 -11.7 77.8 48 64 A I - 0 0 9 -3,-0.1 19,-2.3 -29,-0.0 2,-0.4 -0.742 58.9-157.3 -94.9 138.5 32.4 -13.5 77.5 49 65 A T E - O 0 66C 29 -2,-0.4 -30,-2.1 17,-0.2 2,-0.5 -0.947 2.9-161.8-116.8 135.4 33.4 -16.3 79.9 50 66 A A E -KO 18 65C 1 15,-3.0 15,-2.8 -2,-0.4 2,-0.6 -0.964 5.9-158.5-115.4 127.5 37.0 -17.4 80.7 51 67 A T E +KO 17 64C 17 -34,-2.7 -34,-2.2 -2,-0.5 2,-0.2 -0.935 24.0 165.5-108.9 116.7 37.5 -20.8 82.2 52 68 A G E + O 0 63C 0 11,-2.6 11,-2.4 -2,-0.6 -36,-0.1 -0.702 38.7 51.1-125.0 177.1 40.7 -21.2 84.0 53 69 A G S S+ 0 0 15 -38,-0.5 2,-0.3 -40,-0.4 -1,-0.1 0.202 95.1 67.4 85.4 -12.6 42.6 -23.4 86.5 54 70 A V - 0 0 15 -39,-0.2 -1,-0.1 9,-0.1 3,-0.1 -0.975 57.4-151.6-143.9 154.9 42.0 -26.7 84.8 55 71 A V S S+ 0 0 20 -2,-0.3 73,-1.6 1,-0.2 2,-0.9 0.756 93.3 69.1 -87.9 -29.5 42.9 -28.9 81.8 56 72 A D B > S-Q 127 0D 29 71,-0.2 3,-2.4 1,-0.1 71,-0.2 -0.797 71.0-159.8 -93.7 104.6 39.5 -30.7 82.1 57 73 A L T 3 S+ 0 0 40 69,-2.5 -1,-0.1 -2,-0.9 70,-0.1 0.689 90.8 56.6 -57.1 -19.8 36.7 -28.2 81.2 58 75 A Q T 3 S+ 0 0 138 68,-0.2 -1,-0.3 -3,-0.0 69,-0.1 0.495 81.3 122.7 -90.4 -2.5 34.2 -30.4 83.1 59 76 A S X - 0 0 36 -3,-2.4 3,-1.6 1,-0.2 -5,-0.1 -0.294 64.7-139.0 -63.6 138.8 36.2 -30.3 86.4 60 77 A S T 3 S+ 0 0 124 1,-0.3 -1,-0.2 -2,-0.0 -3,-0.0 0.625 103.5 66.9 -71.3 -10.6 34.4 -28.9 89.5 61 79 A S T 3 S+ 0 0 83 -5,-0.1 -1,-0.3 2,-0.1 -2,-0.1 0.515 75.4 117.1 -86.4 -5.1 37.7 -27.1 90.1 62 80 A A < - 0 0 22 -3,-1.6 2,-0.5 -6,-0.2 -9,-0.2 -0.313 58.4-143.8 -63.7 145.3 37.3 -24.9 87.1 63 81 A V E -O 52 0C 67 -11,-2.4 -11,-2.6 -9,-0.0 2,-0.6 -0.964 12.8-163.1-112.7 121.8 37.0 -21.2 87.7 64 82 A K E +O 51 0C 144 -2,-0.5 2,-0.4 -13,-0.2 -13,-0.2 -0.933 11.9 178.5-112.1 117.5 34.6 -19.4 85.4 65 83 A V E -O 50 0C 3 -15,-2.8 -15,-3.0 -2,-0.6 2,-0.2 -0.946 20.6-132.8-122.1 139.7 34.9 -15.7 85.2 66 84 A R E -O 49 0C 128 -2,-0.4 23,-3.0 -17,-0.2 24,-0.4 -0.532 23.1-116.2 -88.2 153.6 33.0 -13.2 83.1 67 85 A S E - P 0 88C 1 -19,-2.3 21,-0.3 21,-0.3 3,-0.1 -0.373 19.2-171.7 -80.3 164.7 34.5 -10.3 81.1 68 86 A T E S+ 0 0 44 19,-2.4 -23,-2.1 1,-0.4 2,-0.3 0.522 70.2 4.3-124.9 -32.9 33.9 -6.7 81.8 69 87 A K E -NP 44 87C 73 18,-1.1 18,-2.9 -25,-0.3 -1,-0.4 -0.997 55.6-146.3-158.7 153.8 35.6 -5.2 78.8 70 88 A V E -NP 43 86C 6 -27,-2.6 -27,-2.6 -2,-0.3 2,-0.5 -0.939 3.2-168.3-122.6 139.9 37.4 -5.9 75.5 71 89 A L E - P 0 85C 28 14,-2.9 14,-2.5 -2,-0.4 2,-0.3 -0.904 13.2-167.3-129.1 100.9 40.2 -4.1 73.8 72 90 A Q E - P 0 84C 28 -2,-0.5 12,-0.2 12,-0.2 -30,-0.1 -0.693 43.4 -82.9 -87.7 142.0 40.7 -5.3 70.2 73 91 A A > - 0 0 1 10,-2.4 3,-2.0 -2,-0.3 -1,-0.1 -0.157 58.3-101.8 -44.4 122.7 43.9 -4.2 68.4 74 92 A P T 3 S+ 0 0 100 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 -0.212 103.9 12.9 -51.6 134.7 43.2 -0.7 67.0 75 93 A G T 3 S+ 0 0 64 1,-0.2 -2,-0.1 -3,-0.1 0, 0.0 0.544 84.5 166.4 77.0 7.7 42.5 -0.8 63.3 76 94 A Y < + 0 0 56 -3,-2.0 -1,-0.2 1,-0.1 5,-0.1 -0.287 10.5 154.5 -58.6 137.2 42.0 -4.6 63.1 77 95 A N S S- 0 0 124 3,-0.4 -1,-0.1 0, 0.0 4,-0.1 0.155 72.4 -82.1-150.6 20.6 40.4 -5.7 59.9 78 96 A G S S+ 0 0 49 2,-0.4 2,-0.3 3,-0.1 3,-0.1 0.476 105.9 99.8 89.8 3.1 41.6 -9.3 59.4 79 98 A T S S- 0 0 90 1,-0.2 2,-0.2 2,-0.1 -1,-0.0 -0.552 97.3 -53.8-120.7 66.3 45.0 -8.4 57.9 80 100 A G S S+ 0 0 3 -2,-0.3 -2,-0.4 1,-0.1 -3,-0.4 -0.516 100.4 91.4 97.7-170.5 47.4 -8.8 60.7 81 101 A K + 0 0 76 1,-0.2 2,-2.1 -2,-0.2 -8,-0.2 0.848 53.5 173.3 47.6 39.2 47.4 -7.2 64.2 82 102 A D + 0 0 6 71,-0.3 2,-0.3 -46,-0.1 125,-0.2 -0.440 31.1 107.9 -81.9 72.7 45.5 -10.3 65.4 83 103 A W + 0 0 8 -2,-2.1 -10,-2.4 -48,-0.3 2,-0.3 -0.985 35.6 171.4-143.7 153.9 45.5 -9.5 69.1 84 104 A A E -MP 34 72C 0 -50,-2.1 -50,-2.9 -2,-0.3 2,-0.4 -0.980 20.8-139.2-157.3 154.3 43.0 -8.5 71.8 85 105 A L E -MP 33 71C 0 -14,-2.5 -14,-2.9 -2,-0.3 2,-0.5 -0.934 10.8-159.7-118.4 142.5 42.8 -8.1 75.5 86 106 A I E -MP 32 70C 0 -54,-2.0 -54,-2.9 -2,-0.4 2,-0.3 -0.976 10.8-145.5-126.6 116.2 39.8 -9.1 77.7 87 107 A K E -MP 31 69C 40 -18,-2.9 -19,-2.4 -2,-0.5 -18,-1.1 -0.623 19.1-143.8 -78.3 134.1 39.5 -7.6 81.2 88 108 A L E - P 0 67C 6 -58,-3.0 -21,-0.3 -2,-0.3 -39,-0.1 -0.731 14.9-130.1-102.2 152.2 37.9 -10.0 83.7 89 109 A A S S+ 0 0 57 -23,-3.0 -22,-0.1 -2,-0.3 -1,-0.1 0.793 96.9 17.6 -67.6 -30.1 35.5 -9.2 86.5 90 110 A Q S S- 0 0 117 -24,-0.4 2,-0.1 -61,-0.1 -1,-0.1 -0.969 92.1-102.3-138.4 152.5 37.6 -11.1 89.0 91 111 A P - 0 0 77 0, 0.0 2,-0.7 0, 0.0 -61,-0.3 -0.474 23.6-132.0 -78.0 150.1 41.3 -12.3 88.8 92 112 A I - 0 0 2 -63,-2.9 2,-2.2 -2,-0.1 -39,-0.1 -0.915 21.6-135.8 -98.2 116.8 42.1 -15.9 88.0 93 113 A N + 0 0 133 -2,-0.7 3,-0.0 -41,-0.1 -63,-0.0 -0.422 63.5 109.2 -76.7 69.5 44.7 -16.9 90.6 94 118 A Q S S- 0 0 63 -2,-2.2 -2,-0.1 -80,-0.1 -80,-0.1 -0.897 77.9 -76.8-136.2 163.8 47.2 -18.7 88.3 95 119 A P - 0 0 75 0, 0.0 -69,-0.2 0, 0.0 2,-0.2 -0.298 49.5-132.8 -60.6 149.8 50.7 -18.0 87.0 96 120 A T - 0 0 73 -69,-0.1 2,-0.6 -71,-0.1 -69,-0.2 -0.540 12.0-117.5 -98.8 167.9 50.8 -15.5 84.1 97 121 A L - 0 0 4 -71,-2.3 2,-0.1 -2,-0.2 89,-0.1 -0.932 21.2-137.5-113.9 116.2 52.6 -15.7 80.8 98 122 A K E -c 186 0B 123 -2,-0.6 89,-3.0 87,-0.6 2,-0.3 -0.431 20.7-135.3 -66.6 138.7 55.3 -13.2 80.0 99 123 A I E -c 187 0B 12 87,-0.2 2,-0.3 -2,-0.1 89,-0.2 -0.731 20.9-105.2 -99.1 149.9 55.2 -11.9 76.4 100 124 A A - 0 0 0 87,-2.8 113,-0.2 -2,-0.3 -1,-0.0 -0.543 30.4-178.9 -73.5 128.9 58.3 -11.5 74.2 101 125 A T S S+ 0 0 105 -2,-0.3 2,-0.2 112,-0.1 -1,-0.1 0.543 70.1 41.1-103.8 -10.1 59.4 -7.9 73.8 102 128 A T S S- 0 0 73 111,-0.0 3,-0.3 0, 0.0 108,-0.1 -0.690 84.0-117.3-124.0 179.3 62.4 -8.7 71.4 103 129 A T S > S+ 0 0 89 -2,-0.2 3,-1.7 1,-0.2 108,-0.0 0.277 81.7 108.3-103.0 11.0 62.7 -11.1 68.5 104 130 A A T 3 S+ 0 0 55 1,-0.3 -1,-0.2 2,-0.1 -4,-0.0 0.709 83.5 42.9 -60.6 -22.3 65.5 -13.2 70.2 105 131 A Y T 3 S+ 0 0 33 -3,-0.3 2,-1.8 1,-0.1 -1,-0.3 0.228 76.8 108.8-109.6 12.6 63.1 -16.1 70.7 106 132 A N S < S+ 0 0 19 -3,-1.7 2,-0.3 102,-0.0 -1,-0.1 -0.320 77.3 59.5 -84.0 55.4 61.3 -16.1 67.4 107 133 A Q S S+ 0 0 112 -2,-1.8 2,-0.1 2,-0.1 29,-0.0 -0.961 74.9 45.8-166.7 170.3 63.2 -19.3 66.5 108 134 A G S S- 0 0 38 -2,-0.3 27,-2.3 27,-0.1 2,-0.5 -0.440 98.2 -26.9 85.1-159.8 63.6 -22.9 67.7 109 135 A T E -D 134 0B 87 25,-0.2 2,-0.2 -2,-0.1 -2,-0.1 -0.848 63.4-161.0-100.8 125.9 60.9 -25.3 68.8 110 136 A F E -D 133 0B 0 23,-2.4 23,-2.1 -2,-0.5 2,-0.4 -0.496 8.8-137.7 -98.2 169.4 57.6 -23.8 70.1 111 137 A T E -DE 132 177B 11 66,-2.5 66,-2.8 21,-0.2 2,-0.3 -0.980 19.0-177.6-128.3 140.0 54.8 -25.2 72.2 112 138 A V E -DE 131 176B 0 19,-2.5 19,-2.0 -2,-0.4 2,-0.3 -0.897 1.4-173.2-131.7 161.6 51.1 -24.6 71.7 113 139 A A E +D 130 0B 1 62,-0.5 2,-0.3 -2,-0.3 17,-0.2 -0.991 14.8 133.5-156.9 148.7 48.0 -25.7 73.6 114 140 A G E -D 129 0B 0 15,-2.3 15,-2.3 -2,-0.3 57,-0.2 -0.977 54.1-113.1 178.4 171.6 44.2 -25.6 73.2 115 141 A W S S+ 0 0 2 55,-0.5 10,-3.2 -2,-0.3 56,-0.1 0.046 74.1 122.2-107.2 19.7 40.8 -27.2 73.4 116 142 A G S S- 0 0 0 8,-0.2 54,-0.3 1,-0.2 53,-0.1 -0.139 73.3 -59.9 -76.1 178.1 40.2 -26.9 69.7 117 143 A A - 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