==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-SEP-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 17-SEP-10 3OW6 . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.H.PARK . 207 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10657.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 148 71.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 19.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 5.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 30 14.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 53 25.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 17 A V 0 0 121 0, 0.0 2,-0.4 0, 0.0 156,-0.2 0.000 360.0 360.0 360.0 123.0 9.9 -28.9 -8.7 2 18 A E E -A 156 0A 91 154,-2.5 154,-2.3 2,-0.0 2,-0.4 -0.834 360.0-151.6-103.7 138.8 12.3 -26.0 -8.7 3 19 A T E -A 155 0A 97 -2,-0.4 2,-0.3 152,-0.2 152,-0.2 -0.909 15.8-177.4-110.9 135.1 14.1 -24.8 -5.5 4 20 A F E -A 154 0A 54 150,-3.1 150,-2.4 -2,-0.4 2,-0.4 -0.950 23.8-125.3-126.7 155.0 15.1 -21.2 -5.0 5 21 A A E -A 153 0A 79 -2,-0.3 148,-0.3 148,-0.2 2,-0.1 -0.779 29.8-119.1 -94.6 145.0 17.0 -19.3 -2.3 6 22 A F - 0 0 11 146,-1.9 87,-0.2 -2,-0.4 86,-0.1 -0.508 42.3 -90.5 -71.7 154.2 15.3 -16.2 -0.8 7 23 A Q >> - 0 0 75 85,-2.9 4,-2.2 -2,-0.1 3,-0.7 -0.291 47.6-107.4 -58.5 146.9 17.2 -13.0 -1.3 8 24 A A H 3> S+ 0 0 57 1,-0.3 4,-2.3 2,-0.2 5,-0.2 0.843 117.3 51.2 -49.6 -45.2 19.5 -12.7 1.8 9 25 A E H 3> S+ 0 0 48 1,-0.2 4,-2.1 2,-0.2 -1,-0.3 0.845 110.0 49.5 -64.8 -35.5 17.5 -9.9 3.5 10 26 A I H <> S+ 0 0 0 -3,-0.7 4,-3.0 2,-0.2 -1,-0.2 0.906 109.4 51.6 -68.7 -43.2 14.2 -11.8 3.1 11 27 A A H X S+ 0 0 28 -4,-2.2 4,-2.4 2,-0.2 -2,-0.2 0.946 111.6 48.1 -58.6 -40.8 15.8 -14.9 4.6 12 28 A Q H X S+ 0 0 102 -4,-2.3 4,-2.0 1,-0.2 -2,-0.2 0.890 111.3 50.2 -64.3 -39.1 17.0 -12.8 7.6 13 29 A L H X S+ 0 0 2 -4,-2.1 4,-2.4 1,-0.2 -1,-0.2 0.930 109.8 51.2 -67.8 -44.2 13.6 -11.2 8.0 14 30 A M H X S+ 0 0 2 -4,-3.0 4,-3.0 1,-0.2 -2,-0.2 0.924 108.0 50.8 -60.5 -44.7 12.0 -14.6 8.0 15 31 A S H X S+ 0 0 58 -4,-2.4 4,-2.0 1,-0.2 -1,-0.2 0.918 110.3 50.6 -59.7 -42.1 14.3 -16.0 10.7 16 32 A L H X S+ 0 0 71 -4,-2.0 4,-1.0 1,-0.2 -1,-0.2 0.929 114.5 43.5 -57.6 -47.7 13.5 -13.0 12.9 17 33 A I H < S+ 0 0 2 -4,-2.4 3,-0.5 1,-0.2 -2,-0.2 0.904 112.2 53.6 -64.3 -43.1 9.8 -13.5 12.4 18 34 A I H < S+ 0 0 47 -4,-3.0 -1,-0.2 1,-0.2 -2,-0.2 0.838 116.7 36.8 -60.1 -39.8 10.0 -17.3 12.9 19 35 A N H < S+ 0 0 115 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.454 91.6 111.3 -96.5 -6.3 11.8 -17.0 16.2 20 36 A T < - 0 0 31 -4,-1.0 -3,-0.0 -3,-0.5 -4,-0.0 -0.401 56.3-150.7 -74.9 151.3 10.2 -14.0 17.8 21 37 A F + 0 0 195 -2,-0.1 -1,-0.1 4,-0.0 4,-0.1 0.215 41.0 156.5 -99.1 14.8 7.9 -14.0 20.8 22 38 A Y - 0 0 27 1,-0.1 3,-0.2 -5,-0.1 -2,-0.0 -0.130 33.6-150.9 -40.9 126.2 6.1 -10.9 19.4 23 39 A S S S+ 0 0 115 1,-0.2 2,-2.3 2,-0.1 3,-0.3 0.858 78.3 71.1 -78.0 -41.2 2.7 -11.1 21.1 24 40 A N > + 0 0 65 1,-0.2 3,-1.3 2,-0.1 -1,-0.2 -0.328 55.6 149.8 -78.9 58.6 0.3 -9.5 18.6 25 41 A K T > + 0 0 24 -2,-2.3 3,-2.0 1,-0.3 -1,-0.2 0.718 50.1 83.8 -65.3 -24.7 0.5 -12.3 16.1 26 42 A E T >> + 0 0 17 1,-0.3 3,-1.5 -3,-0.3 4,-0.8 0.634 67.7 83.9 -55.2 -19.6 -3.1 -11.8 14.9 27 43 A I H <> S+ 0 0 1 -3,-1.3 4,-2.4 1,-0.3 -1,-0.3 0.741 71.6 78.7 -58.2 -19.0 -1.8 -9.0 12.5 28 44 A F H <> S+ 0 0 0 -3,-2.0 4,-2.1 96,-0.2 -1,-0.3 0.899 92.1 49.7 -58.6 -34.7 -1.0 -11.8 10.0 29 45 A L H <> S+ 0 0 1 -3,-1.5 4,-2.6 1,-0.2 5,-0.3 0.927 107.7 53.1 -75.3 -36.2 -4.6 -12.1 9.0 30 46 A R H X S+ 0 0 67 -4,-0.8 4,-2.4 1,-0.2 -1,-0.2 0.928 110.0 49.0 -59.5 -46.3 -4.9 -8.3 8.5 31 47 A E H X S+ 0 0 16 -4,-2.4 4,-2.2 1,-0.2 -1,-0.2 0.895 112.0 46.6 -62.9 -43.8 -1.9 -8.4 6.2 32 48 A L H X S+ 0 0 5 -4,-2.1 4,-2.4 2,-0.2 -1,-0.2 0.900 113.9 47.7 -67.1 -39.8 -3.1 -11.4 4.0 33 49 A I H X S+ 0 0 0 -4,-2.6 4,-2.8 2,-0.2 -2,-0.2 0.894 111.4 51.7 -68.4 -36.1 -6.6 -9.9 3.7 34 50 A S H X S+ 0 0 43 -4,-2.4 4,-2.3 -5,-0.3 -2,-0.2 0.931 109.7 49.1 -67.9 -37.3 -5.0 -6.5 2.7 35 51 A N H X S+ 0 0 67 -4,-2.2 4,-2.0 1,-0.2 -2,-0.2 0.913 111.8 49.7 -65.2 -43.3 -2.9 -8.3 0.1 36 52 A S H X S+ 0 0 6 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.920 109.3 51.4 -60.0 -46.8 -6.1 -10.0 -1.3 37 53 A S H X S+ 0 0 12 -4,-2.8 4,-2.9 1,-0.2 -2,-0.2 0.927 109.3 50.7 -55.7 -45.9 -7.9 -6.7 -1.4 38 54 A D H X S+ 0 0 88 -4,-2.3 4,-1.9 1,-0.2 -1,-0.2 0.893 110.2 49.5 -59.6 -42.1 -5.1 -5.2 -3.4 39 55 A A H X S+ 0 0 21 -4,-2.0 4,-1.8 2,-0.2 41,-1.7 0.865 111.7 48.4 -64.3 -38.8 -5.1 -8.1 -5.8 40 56 A L H X S+ 0 0 0 -4,-2.3 4,-2.5 39,-0.3 -2,-0.2 0.902 108.6 53.7 -69.0 -43.9 -8.9 -7.7 -6.3 41 57 A D H X S+ 0 0 46 -4,-2.9 4,-2.8 1,-0.2 5,-0.2 0.925 108.5 52.6 -55.4 -42.6 -8.6 -4.0 -6.8 42 58 A K H X S+ 0 0 128 -4,-1.9 4,-1.9 2,-0.2 -2,-0.2 0.919 111.5 41.3 -63.7 -48.6 -6.1 -4.8 -9.6 43 59 A I H X S+ 0 0 0 -4,-1.8 4,-1.5 2,-0.2 -1,-0.2 0.919 114.5 54.9 -66.3 -36.7 -8.2 -7.2 -11.6 44 60 A R H < S+ 0 0 123 -4,-2.5 4,-0.4 1,-0.2 -2,-0.2 0.920 109.3 45.2 -64.6 -45.3 -11.2 -5.0 -11.1 45 61 A Y H >X S+ 0 0 150 -4,-2.8 3,-1.4 1,-0.2 4,-0.6 0.900 111.5 52.6 -65.0 -41.3 -9.5 -1.8 -12.5 46 62 A E H 3X S+ 0 0 60 -4,-1.9 4,-1.6 1,-0.3 3,-0.4 0.763 102.8 60.3 -63.1 -29.5 -8.0 -3.8 -15.5 47 63 A T H 3< S+ 0 0 18 -4,-1.5 -1,-0.3 1,-0.2 -2,-0.2 0.583 89.3 70.4 -76.6 -8.3 -11.5 -5.0 -16.3 48 64 A L H <4 S+ 0 0 136 -3,-1.4 -1,-0.2 -4,-0.4 -2,-0.2 0.881 111.3 30.8 -72.7 -37.7 -12.8 -1.5 -16.8 49 65 A T H < S+ 0 0 127 -4,-0.6 -2,-0.2 -3,-0.4 -1,-0.1 0.744 135.4 28.4 -90.3 -26.3 -10.7 -1.3 -20.0 50 66 A D >< - 0 0 62 -4,-1.6 3,-2.1 1,-0.1 -1,-0.2 -0.724 60.8-173.8-140.2 92.8 -10.9 -5.0 -20.9 51 67 A P G > S+ 0 0 93 0, 0.0 3,-2.0 0, 0.0 -1,-0.1 0.724 79.3 75.5 -53.2 -29.9 -14.0 -6.9 -19.7 52 68 A S G > S+ 0 0 57 1,-0.3 3,-1.6 2,-0.2 4,-0.3 0.639 74.8 81.2 -63.7 -10.6 -12.6 -10.2 -21.0 53 69 A K G X S+ 0 0 57 -3,-2.1 3,-0.5 1,-0.3 -1,-0.3 0.768 90.3 52.2 -66.4 -19.9 -10.2 -10.1 -17.9 54 70 A L G X S+ 0 0 26 -3,-2.0 3,-2.0 1,-0.2 -1,-0.3 0.330 75.8 100.4 -98.2 10.4 -13.1 -11.5 -15.9 55 71 A D G < S+ 0 0 135 -3,-1.6 -1,-0.2 1,-0.3 3,-0.2 0.774 81.5 56.7 -60.7 -26.4 -13.8 -14.4 -18.3 56 72 A S G < S- 0 0 37 -3,-0.5 -1,-0.3 1,-0.3 -2,-0.1 0.443 134.1 -28.2 -82.9 -4.2 -11.8 -16.5 -15.7 57 73 A G < - 0 0 29 -3,-2.0 -1,-0.3 108,-0.1 -2,-0.1 -0.335 44.2-156.3 153.7 125.2 -14.3 -15.4 -13.0 58 74 A K + 0 0 161 -3,-0.2 2,-0.1 -2,-0.1 -3,-0.1 0.788 67.3 96.6 -89.3 -27.9 -16.6 -12.5 -12.3 59 75 A E - 0 0 142 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.407 55.6-161.4 -67.1 136.2 -16.9 -12.8 -8.5 60 76 A L + 0 0 34 -2,-0.1 2,-0.3 17,-0.1 19,-0.1 -0.938 37.8 119.8-120.4 104.3 -14.6 -10.7 -6.4 61 77 A H - 0 0 26 -2,-0.6 17,-1.4 139,-0.1 2,-0.4 -0.962 53.0-125.9-156.3 174.8 -14.3 -12.0 -2.9 62 78 A I E -Bc 77 202A 0 139,-2.5 141,-2.4 -2,-0.3 2,-0.4 -0.991 21.8-166.8-131.3 123.5 -12.2 -13.3 -0.0 63 79 A N E -Bc 76 203A 26 13,-2.5 13,-3.1 -2,-0.4 2,-0.5 -0.920 8.0-154.3-112.9 141.7 -13.0 -16.6 1.7 64 80 A L E -Bc 75 204A 2 139,-2.7 141,-3.1 -2,-0.4 11,-0.2 -0.949 14.3-176.2-113.4 121.3 -11.5 -17.7 5.1 65 81 A I E -B 74 0A 55 9,-3.0 9,-2.1 -2,-0.5 2,-0.2 -0.846 4.5-169.8-127.2 94.9 -11.5 -21.5 5.6 66 82 A P E -B 73 0A 7 0, 0.0 2,-0.4 0, 0.0 7,-0.2 -0.583 1.6-167.8 -79.5 149.4 -10.2 -23.0 8.9 67 83 A N E >> -B 72 0A 43 5,-2.4 5,-1.8 -2,-0.2 4,-1.1 -0.846 9.2-175.6-140.0 97.5 -9.7 -26.7 9.0 68 84 A K T 45S+ 0 0 100 -2,-0.4 -1,-0.1 1,-0.2 3,-0.1 0.854 84.6 56.2 -64.1 -34.7 -9.2 -28.1 12.5 69 85 A Q T 45S+ 0 0 143 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.887 118.4 31.7 -63.7 -43.3 -8.5 -31.7 11.2 70 86 A D T 45S- 0 0 109 2,-0.2 -1,-0.2 -3,-0.1 -2,-0.2 0.510 104.2-127.9 -90.2 -8.1 -5.7 -30.6 8.9 71 87 A R T <5 + 0 0 81 -4,-1.1 103,-1.8 1,-0.2 2,-0.4 0.910 64.7 132.1 56.7 48.5 -4.6 -27.7 11.2 72 88 A T E < -BD 67 173A 15 -5,-1.8 -5,-2.4 101,-0.2 2,-0.5 -0.962 48.0-158.6-129.4 145.1 -4.7 -25.3 8.3 73 89 A L E -BD 66 172A 2 99,-1.8 99,-3.0 -2,-0.4 2,-0.4 -0.997 19.4-162.7-117.0 123.6 -6.2 -21.8 7.8 74 90 A T E -BD 65 171A 18 -9,-2.1 -9,-3.0 -2,-0.5 2,-0.6 -0.914 9.2-164.8-112.5 130.2 -6.8 -21.0 4.1 75 91 A I E -BD 64 170A 2 95,-2.5 95,-2.6 -2,-0.4 2,-0.4 -0.966 14.8-173.7-111.3 114.3 -7.3 -17.5 2.7 76 92 A V E +BD 63 169A 27 -13,-3.1 -13,-2.5 -2,-0.6 2,-0.3 -0.930 7.1 173.8-113.3 137.2 -8.7 -17.6 -0.8 77 93 A D E -BD 62 168A 7 91,-2.8 91,-1.4 -2,-0.4 -15,-0.2 -0.946 31.3-142.3-133.8 160.7 -9.2 -14.6 -3.1 78 94 A T + 0 0 25 -17,-1.4 89,-0.2 -2,-0.3 -16,-0.1 -0.187 59.0 129.0-109.9 39.3 -10.3 -14.2 -6.7 79 95 A G S S- 0 0 0 89,-0.2 -39,-0.3 -18,-0.1 -40,-0.1 0.091 80.1 -65.9 -77.7-158.9 -8.0 -11.3 -7.4 80 96 A I S S- 0 0 14 -41,-1.7 59,-0.6 1,-0.2 87,-0.2 0.670 70.1-155.6 -66.8 -22.4 -5.5 -10.8 -10.3 81 97 A G - 0 0 7 57,-0.2 2,-0.4 85,-0.1 57,-0.2 -0.151 16.8 -78.5 74.7-172.7 -3.2 -13.7 -9.1 82 98 A M - 0 0 34 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.994 25.4-137.1-133.3 138.8 0.5 -14.2 -9.8 83 99 A T > - 0 0 22 -2,-0.4 4,-2.5 54,-0.1 5,-0.2 -0.351 41.7-100.2 -77.5 171.3 2.4 -15.4 -12.8 84 100 A K H > S+ 0 0 52 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.910 127.9 50.4 -56.3 -46.5 5.3 -17.8 -12.1 85 101 A A H > S+ 0 0 63 1,-0.2 4,-2.7 2,-0.2 5,-0.3 0.892 108.6 51.3 -58.8 -44.2 7.7 -14.8 -12.5 86 102 A D H > S+ 0 0 53 2,-0.2 4,-3.0 1,-0.2 5,-0.4 0.897 109.0 51.6 -60.2 -44.1 5.6 -12.7 -10.1 87 103 A L H X>S+ 0 0 0 -4,-2.5 4,-1.8 1,-0.2 5,-0.5 0.944 113.6 43.3 -59.2 -50.2 5.7 -15.6 -7.5 88 104 A I H X5S+ 0 0 42 -4,-2.2 4,-0.8 -5,-0.2 -2,-0.2 0.919 122.7 36.9 -63.9 -45.0 9.5 -15.8 -7.7 89 105 A N H X5S+ 0 0 88 -4,-2.7 4,-1.3 -5,-0.2 -2,-0.2 0.936 120.7 42.4 -73.8 -48.1 10.2 -12.1 -7.7 90 106 A N H <5S+ 0 0 75 -4,-3.0 -3,-0.2 -5,-0.3 -2,-0.2 0.806 127.0 28.4 -74.5 -32.5 7.5 -10.9 -5.3 91 107 A L H <5S+ 0 0 12 -4,-1.8 -1,-0.2 -5,-0.4 -3,-0.2 0.626 124.2 49.0 -99.8 -17.6 7.7 -13.6 -2.6 92 108 A G H < + 0 0 23 -2,-0.2 3,-2.5 1,-0.2 5,-0.2 0.868 63.0 158.9 -62.2 -37.3 12.9 -7.4 -1.6 95 111 A A T 3 S- 0 0 47 1,-0.3 -1,-0.2 -6,-0.1 -5,-0.1 -0.219 70.1 -15.7 53.6-120.9 11.3 -6.4 -4.8 96 112 A K T 3 S+ 0 0 208 -3,-0.2 -1,-0.3 23,-0.1 -2,-0.1 0.398 110.7 111.3 -93.5 0.9 9.4 -3.1 -4.3 97 113 A S S < S- 0 0 26 -3,-2.5 3,-0.3 -4,-0.1 22,-0.2 -0.241 75.2-122.3 -77.3 168.2 9.3 -3.3 -0.5 98 114 A G > + 0 0 30 20,-2.3 4,-2.2 1,-0.2 3,-0.3 -0.191 61.6 138.8 -97.1 37.9 11.0 -1.2 2.2 99 115 A T H > + 0 0 0 -5,-0.2 4,-3.2 1,-0.2 5,-0.3 0.920 65.8 52.1 -47.6 -54.3 12.7 -4.4 3.6 100 116 A K H > S+ 0 0 132 -3,-0.3 4,-2.0 1,-0.2 -1,-0.2 0.873 111.2 46.1 -56.8 -39.4 16.1 -2.8 4.3 101 117 A A H > S+ 0 0 48 -3,-0.3 4,-2.8 2,-0.2 -1,-0.2 0.868 113.1 51.3 -70.6 -35.5 14.6 0.1 6.3 102 118 A F H < S+ 0 0 19 -4,-2.2 -2,-0.2 2,-0.2 -1,-0.2 0.962 109.7 48.4 -65.1 -47.7 12.5 -2.4 8.2 103 119 A M H < S+ 0 0 40 -4,-3.2 3,-0.4 1,-0.2 -2,-0.2 0.896 114.0 48.2 -59.7 -37.6 15.5 -4.5 9.0 104 120 A E H >< S+ 0 0 148 -4,-2.0 2,-3.2 -5,-0.3 3,-0.5 0.930 92.3 81.5 -66.4 -43.1 17.3 -1.3 10.1 105 121 A A T 3< + 0 0 13 -4,-2.8 4,-0.4 1,-0.3 -1,-0.2 0.014 55.5 99.4 -59.4 36.8 14.3 -0.2 12.3 106 122 A L T 3 S+ 0 0 117 -2,-3.2 -1,-0.3 -3,-0.4 -2,-0.1 0.228 97.6 35.5 -99.3 7.9 15.3 -2.5 15.2 107 123 A Q S < S+ 0 0 168 -3,-0.5 -2,-0.2 4,-0.1 -1,-0.1 0.166 99.7 79.1-142.4 10.1 16.6 0.8 16.4 108 124 A A S S- 0 0 87 2,-0.4 -2,-0.1 3,-0.1 3,-0.1 0.868 110.4 -91.8 -89.9 -42.5 14.0 3.3 15.1 109 125 A G S S+ 0 0 78 1,-0.5 2,-0.3 -4,-0.4 -3,-0.1 0.004 96.6 86.6 155.9 -33.5 11.3 2.8 17.7 110 126 A A - 0 0 28 1,-0.2 -1,-0.5 -5,-0.1 -2,-0.4 -0.699 54.8-159.9 -96.4 146.1 9.0 0.1 16.4 111 127 A D - 0 0 95 -2,-0.3 3,-0.3 -3,-0.1 -1,-0.2 0.583 66.2 -40.4 -87.9-120.5 9.6 -3.7 16.8 112 128 A I S > S+ 0 0 27 1,-0.2 3,-1.3 2,-0.1 -2,-0.1 0.607 117.6 92.4 -84.2 -15.3 8.0 -6.3 14.6 113 129 A S T 3 S+ 0 0 47 1,-0.2 3,-0.4 2,-0.1 -1,-0.2 0.710 74.9 53.2 -55.8 -34.3 4.7 -4.3 14.6 114 130 A M T >> + 0 0 73 -3,-0.3 3,-1.5 1,-0.2 4,-0.7 0.298 67.7 122.5 -92.8 16.2 5.0 -2.1 11.5 115 131 A I G X4>S+ 0 0 1 -3,-1.3 3,-1.5 1,-0.3 5,-1.5 0.832 70.7 54.5 -42.9 -50.6 5.7 -4.9 9.0 116 132 A G G >45S+ 0 0 23 -3,-0.4 3,-1.3 1,-0.3 5,-0.3 0.814 101.2 57.6 -58.1 -34.0 2.7 -4.0 6.8 117 133 A Q G <45S+ 0 0 149 -3,-1.5 -1,-0.3 1,-0.3 -2,-0.2 0.655 102.8 56.7 -75.1 -10.3 3.7 -0.4 6.3 118 134 A F G <<5S- 0 0 49 -3,-1.5 -20,-2.3 -4,-0.7 -1,-0.3 0.206 117.0-110.7-102.3 12.0 7.1 -1.6 4.9 119 135 A G T < 5S+ 0 0 57 -3,-1.3 -3,-0.2 -22,-0.2 3,-0.1 0.649 96.5 98.2 71.5 16.7 5.5 -3.7 2.1 120 136 A V > < + 0 0 6 -5,-1.5 3,-1.6 1,-0.1 4,-0.3 0.063 35.0 126.8-120.1 24.9 6.5 -7.1 3.6 121 137 A G G > + 0 0 5 -6,-0.3 3,-2.0 -5,-0.3 4,-0.3 0.791 60.4 72.9 -51.6 -36.7 3.2 -7.9 5.4 122 138 A F G > S+ 0 0 17 1,-0.3 3,-1.7 2,-0.2 -1,-0.3 0.844 88.6 60.4 -46.4 -42.0 3.0 -11.3 3.7 123 139 A Y G X S+ 0 0 6 -3,-1.6 3,-1.8 1,-0.3 -1,-0.3 0.641 80.7 81.4 -71.1 -11.4 5.9 -12.7 5.9 124 140 A S G X S+ 0 0 0 -3,-2.0 3,-2.1 -4,-0.3 4,-0.5 0.648 72.4 82.1 -64.9 -16.8 3.9 -12.1 9.1 125 141 A A G X> S+ 0 0 0 -3,-1.7 4,-2.0 -4,-0.3 3,-1.4 0.867 79.8 66.6 -55.5 -32.6 2.3 -15.4 8.1 126 142 A Y G <4 S+ 0 0 1 -3,-1.8 -1,-0.3 1,-0.3 -2,-0.2 0.583 82.2 73.7 -70.0 -5.3 5.3 -17.0 9.7 127 143 A L G <4 S+ 0 0 1 -3,-2.1 -1,-0.3 1,-0.1 -2,-0.2 0.849 118.6 15.9 -70.1 -35.3 4.3 -15.7 13.1 128 144 A V T <4 S+ 0 0 0 -3,-1.4 47,-3.0 -4,-0.5 2,-0.4 0.632 117.9 70.8-112.6 -18.7 1.6 -18.4 13.1 129 145 A A E < -E 174 0A 0 -4,-2.0 45,-0.3 45,-0.3 3,-0.1 -0.859 49.2-163.7-110.2 140.5 2.5 -20.9 10.4 130 146 A E E S+ 0 0 110 43,-2.5 2,-0.3 -2,-0.4 44,-0.1 0.772 90.5 14.0 -84.4 -24.3 5.4 -23.5 10.2 131 147 A K E -E 173 0A 61 42,-1.2 42,-2.6 -6,-0.1 2,-0.4 -0.990 67.6-157.9-149.6 146.8 4.8 -23.7 6.5 132 148 A V E -EF 172 148A 0 16,-2.0 16,-2.1 -2,-0.3 2,-0.4 -0.999 4.1-167.6-127.5 135.6 2.9 -21.6 3.9 133 149 A T E -EF 171 147A 9 38,-2.4 38,-3.4 -2,-0.4 2,-0.5 -0.965 3.9-164.3-118.6 137.7 1.7 -22.8 0.5 134 150 A V E -EF 170 146A 1 12,-3.1 12,-2.9 -2,-0.4 2,-0.5 -0.979 1.9-169.3-123.2 119.9 0.5 -20.3 -2.1 135 151 A I E +EF 169 145A 10 34,-2.9 34,-2.8 -2,-0.5 2,-0.3 -0.923 19.0 177.0-106.2 130.2 -1.5 -21.6 -5.0 136 152 A T E -EF 168 144A 0 8,-2.8 8,-2.3 -2,-0.5 2,-0.4 -0.987 25.6-172.0-143.8 148.9 -2.1 -19.0 -7.7 137 153 A K E -E 167 0A 45 30,-2.4 30,-2.3 -2,-0.3 2,-0.3 -0.957 9.7-174.8-138.0 118.4 -3.6 -18.5 -11.2 138 154 A H > - 0 0 20 4,-0.5 3,-1.5 -56,-0.4 -57,-0.2 -0.770 37.5-116.6-109.5 153.2 -3.0 -15.3 -13.2 139 155 A N T 3 S+ 0 0 49 -59,-0.6 -1,-0.1 -2,-0.3 -58,-0.1 0.844 114.5 52.9 -57.7 -32.9 -4.8 -14.7 -16.6 140 156 A D T 3 S+ 0 0 129 2,-0.1 2,-0.3 -3,-0.0 -1,-0.2 0.439 114.3 27.4 -84.5 1.9 -1.4 -14.7 -18.3 141 157 A D S < S- 0 0 49 -3,-1.5 2,-0.1 1,-0.1 3,-0.1 -0.852 83.1 -84.9-148.0-176.7 0.0 -18.0 -17.0 142 158 A E - 0 0 112 -2,-0.3 -4,-0.5 1,-0.1 2,-0.3 -0.303 58.1 -81.5 -86.9 178.4 -0.7 -21.5 -15.7 143 159 A Q - 0 0 18 16,-0.2 16,-2.5 -6,-0.2 2,-0.3 -0.647 52.2-175.1 -87.5 134.4 -1.5 -22.4 -12.1 144 160 A Y E -FG 136 158A 23 -8,-2.3 -8,-2.8 -2,-0.3 2,-0.5 -0.915 20.7-144.3-131.8 154.0 1.5 -22.7 -9.8 145 161 A A E -FG 135 157A 8 12,-2.9 12,-2.2 -2,-0.3 2,-0.4 -0.993 15.4-171.5-121.8 124.0 2.1 -23.7 -6.2 146 162 A W E +FG 134 156A 0 -12,-2.9 -12,-3.1 -2,-0.5 2,-0.3 -0.875 13.1 175.4-106.6 147.5 4.8 -21.9 -4.2 147 163 A E E +FG 133 155A 50 8,-1.9 8,-2.3 -2,-0.4 2,-0.3 -0.986 11.4 169.6-153.7 152.0 5.8 -23.2 -0.8 148 164 A S E -F 132 0A 6 -16,-2.1 -16,-2.0 -2,-0.3 6,-0.1 -0.954 27.9-169.5-163.3 140.2 8.2 -22.6 2.0 149 165 A S - 0 0 75 1,-0.5 5,-0.1 -2,-0.3 -18,-0.1 -0.089 58.9-118.8-110.4 30.7 8.9 -23.6 5.7 150 166 A A S > S+ 0 0 13 3,-0.3 3,-0.9 1,-0.1 -1,-0.5 -0.358 72.3 130.8 63.0-144.7 11.5 -20.8 5.8 151 167 A G T 3 S- 0 0 85 1,-0.2 -1,-0.1 -140,-0.2 3,-0.1 0.623 100.1 -65.2 75.4 2.5 15.1 -22.1 6.4 152 168 A G T 3 S+ 0 0 27 1,-0.2 -146,-1.9 -141,-0.1 2,-0.3 0.380 112.1 71.3 105.3 -8.8 16.2 -20.0 3.5 153 169 A S E < -A 5 0A 55 -3,-0.9 -3,-0.3 -148,-0.3 -4,-0.3 -0.920 48.4-167.9-138.1 163.2 14.6 -21.6 0.4 154 170 A F E -A 4 0A 5 -150,-2.4 -150,-3.1 -2,-0.3 2,-0.3 -0.957 15.6-134.4-142.8 162.9 11.3 -22.0 -1.3 155 171 A T E -AG 3 147A 23 -8,-2.3 -8,-1.9 -2,-0.3 2,-0.4 -0.871 8.5-163.1-120.4 156.1 9.9 -24.2 -4.1 156 172 A V E +AG 2 146A 1 -154,-2.3 -154,-2.5 -2,-0.3 2,-0.3 -0.999 18.3 163.1-135.4 134.2 7.8 -23.5 -7.1 157 173 A R E - G 0 145A 97 -12,-2.2 -12,-2.9 -2,-0.4 2,-0.2 -0.977 45.6 -94.0-147.1 153.4 6.0 -26.2 -9.1 158 174 A T E - G 0 144A 67 -2,-0.3 2,-0.7 -14,-0.2 -14,-0.3 -0.511 43.0-134.1 -61.9 137.0 3.2 -26.4 -11.7 159 175 A D + 0 0 43 -16,-2.5 -16,-0.2 -2,-0.2 -1,-0.1 -0.874 29.4 174.2-103.8 117.2 -0.1 -27.1 -9.8 160 176 A T + 0 0 136 -2,-0.7 -1,-0.1 3,-0.1 -16,-0.0 0.365 50.5 106.0 -97.4 1.4 -2.2 -29.8 -11.3 161 177 A G S S- 0 0 37 1,-0.2 3,-0.1 -18,-0.0 -18,-0.1 0.212 87.8 -28.4 -64.5-166.7 -4.7 -29.7 -8.4 162 178 A E S S- 0 0 158 1,-0.1 -1,-0.2 2,-0.1 2,-0.0 -0.253 73.9-119.6 -50.6 121.0 -8.2 -28.2 -8.4 163 179 A P - 0 0 99 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.344 23.0-165.3 -63.0 141.5 -8.2 -25.4 -11.0 164 180 A M - 0 0 43 3,-0.1 2,-2.2 1,-0.1 -27,-0.1 0.481 21.4-137.9-110.6 -1.8 -9.1 -22.0 -9.5 165 181 A G S S- 0 0 34 -27,-0.1 2,-0.2 2,-0.0 -108,-0.1 -0.333 75.1 -18.8 79.5 -58.7 -9.9 -20.0 -12.5 166 182 A R S S+ 0 0 3 -2,-2.2 2,-0.3 -89,-0.1 -28,-0.2 -0.822 100.2 58.4-176.7 137.3 -8.0 -16.9 -11.3 167 183 A G E - E 0 137A 0 -30,-2.3 -30,-2.4 -2,-0.2 2,-0.4 -0.834 68.9 -76.8 133.6-167.0 -6.8 -15.7 -7.9 168 184 A T E -DE 77 136A 11 -91,-1.4 -91,-2.8 -2,-0.3 2,-0.4 -0.993 23.3-163.9-141.3 136.7 -4.6 -16.7 -5.0 169 185 A K E -DE 76 135A 57 -34,-2.8 -34,-2.9 -2,-0.4 2,-0.5 -0.993 7.3-163.1-120.3 127.1 -5.0 -19.2 -2.2 170 186 A V E -DE 75 134A 13 -95,-2.6 -95,-2.5 -2,-0.4 2,-0.6 -0.957 5.2-163.2-111.5 121.0 -2.7 -19.0 0.8 171 187 A I E -DE 74 133A 32 -38,-3.4 -38,-2.4 -2,-0.5 2,-0.7 -0.921 2.6-159.0-110.1 117.7 -2.6 -22.1 3.0 172 188 A L E -DE 73 132A 0 -99,-3.0 -99,-1.8 -2,-0.6 2,-1.1 -0.855 5.7-155.6 -98.1 115.9 -1.2 -21.6 6.5 173 189 A H E -DE 72 131A 41 -42,-2.6 -43,-2.5 -2,-0.7 -42,-1.2 -0.737 33.8-133.4 -88.2 98.4 0.0 -24.9 8.0 174 190 A L E - E 0 129A 1 -103,-1.8 -45,-0.3 -2,-1.1 5,-0.1 -0.199 5.2-112.1 -67.2 146.0 -0.3 -23.7 11.6 175 191 A K > - 0 0 36 -47,-3.0 3,-2.4 1,-0.1 -1,-0.1 -0.415 37.7-109.9 -65.5 147.9 2.2 -24.1 14.4 176 192 A E G > S+ 0 0 150 1,-0.3 3,-0.5 2,-0.1 -1,-0.1 0.780 117.2 47.6 -55.7 -29.9 0.9 -26.4 17.1 177 193 A D G 3 S+ 0 0 107 1,-0.2 -1,-0.3 2,-0.1 3,-0.2 0.310 100.9 66.5 -96.2 13.0 0.4 -23.7 19.6 178 194 A Q G X + 0 0 16 -3,-2.4 3,-1.5 -50,-0.2 -1,-0.2 0.035 56.7 119.5-120.3 28.3 -1.4 -21.3 17.3 179 195 A T G X + 0 0 58 -3,-0.5 3,-2.0 1,-0.3 4,-0.2 0.541 51.3 88.6 -73.5 -3.8 -4.6 -23.2 16.7 180 196 A E G > S+ 0 0 79 1,-0.3 3,-1.6 -3,-0.2 -1,-0.3 0.804 78.0 68.3 -60.7 -25.1 -6.7 -20.4 18.2 181 197 A Y G < S+ 0 0 5 -3,-1.5 -1,-0.3 1,-0.3 -2,-0.1 0.399 91.1 58.9 -77.0 5.4 -6.7 -19.1 14.6 182 198 A L G < S+ 0 0 5 -3,-2.0 2,-0.4 -116,-0.1 -1,-0.3 0.393 84.3 102.5-104.0 -5.5 -8.9 -22.0 13.6 183 199 A E S <> S- 0 0 85 -3,-1.6 4,-2.5 -4,-0.2 3,-0.2 -0.692 70.2-140.9 -85.8 127.1 -11.6 -21.0 16.1 184 200 A E H > S+ 0 0 80 -2,-0.4 4,-2.6 1,-0.2 5,-0.2 0.893 101.2 52.4 -51.1 -47.1 -14.6 -19.2 14.6 185 201 A R H > S+ 0 0 209 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.900 111.7 45.9 -60.1 -40.7 -14.9 -16.7 17.5 186 202 A R H > S+ 0 0 40 -6,-0.3 4,-2.1 -3,-0.2 5,-0.2 0.942 112.0 50.0 -69.0 -44.7 -11.2 -15.7 17.2 187 203 A I H X S+ 0 0 2 -4,-2.5 4,-2.2 -7,-0.2 5,-0.2 0.957 110.9 50.9 -58.7 -49.3 -11.4 -15.3 13.4 188 204 A K H X S+ 0 0 111 -4,-2.6 4,-2.5 1,-0.2 -1,-0.2 0.920 109.5 49.3 -53.3 -50.1 -14.5 -13.2 13.7 189 205 A E H X S+ 0 0 81 -4,-2.1 4,-2.1 1,-0.2 -1,-0.2 0.864 111.5 48.8 -61.0 -37.1 -12.9 -10.8 16.3 190 206 A I H X S+ 0 0 0 -4,-2.1 4,-2.1 2,-0.2 5,-0.4 0.881 111.7 48.6 -69.6 -39.2 -9.7 -10.3 14.2 191 207 A V H X>S+ 0 0 28 -4,-2.2 4,-2.6 -5,-0.2 5,-0.9 0.937 112.9 48.4 -66.1 -46.4 -11.6 -9.6 11.1 192 208 A K H <5S+ 0 0 137 -4,-2.5 4,-0.4 -5,-0.2 -2,-0.2 0.901 116.0 43.6 -59.7 -42.0 -13.8 -7.1 12.9 193 209 A K H <5S+ 0 0 110 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.835 132.3 14.7 -74.9 -35.3 -10.9 -5.3 14.5 194 210 A H H <5S+ 0 0 51 -4,-2.1 -3,-0.2 -5,-0.1 -2,-0.2 0.599 133.4 29.4-116.2 -17.9 -8.5 -5.1 11.6 195 211 A S T ><5S+ 0 0 5 -4,-2.6 3,-2.1 -5,-0.4 -3,-0.2 0.383 73.1 116.2-130.0 2.5 -10.3 -5.8 8.3 196 212 A Q T 3