==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 07-APR-03 1OZ3 . COMPND 2 MOLECULE: LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR W.K.WANG,V.TERESHKO,P.BOCCUNI,D.MACGROGAN,S.D.NIMER,D.J.PATE . 939 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 48477.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 546 58.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 42 4.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 198 21.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 12 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 55 5.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 133 14.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 9.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 16 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 9 0 3 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 12 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 9 3 6 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 206 A W 0 0 151 0, 0.0 2,-0.3 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 127.9 -21.0 52.0 -21.1 2 207 A S > - 0 0 38 1,-0.1 4,-1.4 0, 0.0 5,-0.1 -0.978 360.0-129.1-141.0 152.1 -22.7 55.1 -19.8 3 208 A W H > S+ 0 0 35 -2,-0.3 4,-2.9 2,-0.2 5,-0.2 0.898 108.8 54.7 -61.3 -49.9 -25.1 55.9 -16.9 4 209 A E H 4 S+ 0 0 148 1,-0.2 4,-0.4 2,-0.2 -1,-0.1 0.952 109.4 46.1 -49.8 -52.6 -27.6 57.7 -19.2 5 210 A S H >> S+ 0 0 64 1,-0.2 4,-1.8 2,-0.2 3,-0.7 0.881 114.6 48.8 -63.1 -36.5 -27.9 54.7 -21.6 6 211 A Y H 3X S+ 0 0 14 -4,-1.4 4,-1.6 1,-0.2 5,-0.3 0.946 105.3 55.5 -67.8 -46.6 -28.4 52.4 -18.6 7 212 A L H 3<>S+ 0 0 34 -4,-2.9 5,-1.2 1,-0.2 -1,-0.2 0.571 110.2 53.4 -59.9 -7.1 -31.0 54.6 -16.9 8 213 A E H <45S+ 0 0 136 -3,-0.7 -1,-0.2 -4,-0.4 -2,-0.2 0.882 108.8 40.0 -98.4 -50.6 -32.8 54.2 -20.2 9 214 A E H <5S+ 0 0 140 -4,-1.8 -2,-0.2 1,-0.2 -3,-0.1 0.612 125.1 41.7 -74.0 -12.5 -32.9 50.5 -20.8 10 215 A Q T <5S- 0 0 98 -4,-1.6 -1,-0.2 -5,-0.2 -2,-0.2 0.622 97.3-138.8-105.2 -12.7 -33.7 50.1 -17.1 11 216 A K T 5 + 0 0 180 -5,-0.3 2,-0.2 1,-0.2 -3,-0.2 0.964 59.8 138.5 47.8 54.5 -36.1 53.1 -16.9 12 217 A A < - 0 0 17 -5,-1.2 2,-0.3 -6,-0.2 -1,-0.2 -0.638 46.7-136.8-126.9 177.7 -34.4 53.7 -13.7 13 218 A I - 0 0 112 234,-0.5 236,-1.9 -2,-0.2 2,-0.3 -0.946 14.8-120.5-139.4 150.2 -33.2 56.7 -11.8 14 219 A T B -a 249 0A 40 -2,-0.3 236,-0.2 234,-0.2 234,-0.1 -0.760 36.3-101.5 -94.1 143.4 -30.0 57.6 -9.8 15 220 A A - 0 0 3 234,-2.5 284,-0.4 -2,-0.3 229,-0.1 -0.463 51.0-109.9 -50.3 120.3 -30.0 58.6 -6.2 16 221 A P > - 0 0 56 0, 0.0 3,-2.1 0, 0.0 4,-0.4 -0.276 17.4-119.8 -57.0 144.5 -29.7 62.4 -6.3 17 222 A V G > S+ 0 0 96 1,-0.3 3,-1.8 2,-0.2 8,-0.1 0.860 110.5 68.2 -51.7 -38.7 -26.4 63.9 -5.2 18 223 A S G 3 S+ 0 0 103 1,-0.3 -1,-0.3 7,-0.0 4,-0.1 0.678 89.2 65.2 -59.8 -16.8 -28.3 65.9 -2.5 19 224 A L G < S+ 0 0 38 -3,-2.1 -1,-0.3 2,-0.1 224,-0.2 0.711 94.6 74.4 -76.8 -19.2 -29.1 62.5 -0.6 20 225 A F S < S- 0 0 12 -3,-1.8 2,-0.2 -4,-0.4 272,-0.1 -0.540 91.2-102.7 -95.5 153.8 -25.4 61.9 0.0 21 226 A Q >> - 0 0 97 270,-0.3 4,-1.5 -2,-0.2 3,-1.5 -0.504 36.5-111.8 -66.4 146.0 -23.1 63.6 2.5 22 227 A D H 3> S+ 0 0 145 1,-0.3 4,-2.3 2,-0.2 3,-0.5 0.880 119.2 55.6 -42.7 -47.7 -20.7 66.2 1.1 23 228 A S H 34 S+ 0 0 69 1,-0.2 -1,-0.3 2,-0.2 58,-0.1 0.766 108.6 46.5 -61.1 -30.9 -17.8 63.9 1.8 24 229 A Q H <4 S+ 0 0 1 -3,-1.5 -1,-0.2 1,-0.1 -2,-0.2 0.753 119.2 40.5 -78.9 -27.0 -19.4 61.0 -0.2 25 230 A A H < S+ 0 0 25 -4,-1.5 -2,-0.2 -3,-0.5 -3,-0.1 0.761 81.4 113.6 -95.0 -27.1 -20.3 63.2 -3.2 26 231 A V < + 0 0 31 -4,-2.3 -5,-0.0 -5,-0.2 -4,-0.0 -0.208 25.1 157.6 -65.3 123.5 -17.2 65.5 -3.6 27 232 A T + 0 0 37 1,-0.1 -1,-0.1 277,-0.0 273,-0.0 0.496 55.8 75.1-116.1 -8.0 -15.4 64.8 -6.9 28 233 A H S S+ 0 0 154 2,-0.1 2,-0.3 277,-0.0 -2,-0.1 0.326 71.5 97.5 -97.9 6.1 -13.5 68.0 -7.7 29 234 A N S S- 0 0 72 1,-0.0 2,-0.2 32,-0.0 52,-0.1 -0.720 73.0-126.4 -92.5 144.9 -10.7 67.5 -5.1 30 235 A K - 0 0 193 -2,-0.3 2,-0.9 1,-0.0 -2,-0.1 -0.632 14.1-119.9 -92.7 151.8 -7.5 66.1 -6.3 31 236 A N + 0 0 24 -2,-0.2 31,-0.1 1,-0.1 29,-0.1 -0.821 31.5 178.0 -86.5 103.5 -5.8 63.1 -4.8 32 237 A G + 0 0 24 -2,-0.9 2,-0.2 95,-0.1 -1,-0.1 0.422 41.5 115.1 -87.5 -2.1 -2.5 64.5 -3.7 33 238 A F - 0 0 3 94,-0.1 2,-0.3 90,-0.1 -2,-0.1 -0.532 48.9-164.7 -73.0 139.8 -1.3 61.2 -2.1 34 239 A K > - 0 0 122 -2,-0.2 3,-2.2 1,-0.0 21,-0.3 -0.921 30.5 -81.9-128.7 148.5 1.7 59.7 -3.9 35 240 A L T 3 S+ 0 0 126 -2,-0.3 21,-0.2 1,-0.3 3,-0.1 -0.215 113.6 14.9 -51.1 131.0 3.3 56.2 -3.9 36 241 A G T 3 S+ 0 0 36 19,-2.7 85,-0.3 1,-0.3 -1,-0.3 0.276 85.7 142.6 84.6 -7.4 5.7 55.7 -1.0 37 242 A X < - 0 0 11 -3,-2.2 18,-2.7 83,-0.1 2,-0.3 -0.418 44.0-134.3 -61.4 144.1 4.4 58.7 1.1 38 243 A K E +Gh 54 122B 24 83,-2.2 85,-2.5 16,-0.2 50,-0.4 -0.788 35.6 144.9-106.5 147.1 4.4 58.0 4.8 39 244 A L E -G 53 0B 0 14,-2.4 14,-2.5 -2,-0.3 2,-0.3 -0.853 39.5-103.3-159.6-174.6 1.6 58.8 7.3 40 245 A E E +GI 52 86B 0 46,-2.7 46,-2.6 -2,-0.2 2,-0.3 -0.892 41.8 145.7-123.0 153.1 -0.3 57.6 10.4 41 246 A G E -GI 51 85B 0 10,-1.8 10,-2.4 -2,-0.3 44,-0.2 -0.956 42.8 -79.5-178.1 169.3 -3.6 56.0 10.7 42 247 A I E -G 50 0B 13 42,-2.1 8,-0.2 -2,-0.3 3,-0.1 -0.358 38.0-118.3 -75.4 154.6 -5.9 53.5 12.5 43 248 A D E > -G 46 0B 18 6,-1.9 3,-1.7 3,-0.8 6,-0.3 -0.813 21.2-146.0 -83.3 115.1 -6.0 49.8 11.9 44 249 A P T 3 S+ 0 0 71 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.820 101.1 49.7 -54.4 -30.0 -9.5 49.2 10.6 45 250 A Q T 3 S+ 0 0 132 1,-0.3 -2,-0.0 -3,-0.1 -3,-0.0 0.593 125.2 29.0 -79.3 -16.4 -9.6 45.8 12.3 46 251 A H E X S-G 43 0B 64 -3,-1.7 3,-2.6 3,-0.2 -3,-0.8 -0.587 76.1-178.3-142.8 72.6 -8.4 47.4 15.6 47 252 A P E 3 S+ 0 0 13 0, 0.0 -5,-0.1 0, 0.0 133,-0.1 0.440 75.9 61.1 -70.1 -1.3 -9.8 51.0 15.3 48 253 A S E 3 S+ 0 0 47 -5,-0.1 2,-0.4 131,-0.1 132,-0.0 0.510 93.4 84.0 -88.4 -13.0 -8.3 52.2 18.6 49 254 A X E < - 0 0 57 -3,-2.6 -6,-1.9 -6,-0.3 2,-0.4 -0.802 63.8-151.2-107.8 139.5 -4.8 51.5 17.4 50 255 A Y E +Gj 42 98B 4 47,-0.6 49,-2.7 -2,-0.4 2,-0.3 -0.859 16.4 177.0-113.6 137.3 -2.5 53.7 15.3 51 256 A F E -Gj 41 99B 22 -10,-2.4 -10,-1.8 -2,-0.4 2,-0.5 -0.905 37.3-101.5-132.2 159.7 0.3 52.6 12.9 52 257 A I E -G 40 0B 3 47,-0.7 16,-1.5 -2,-0.3 2,-0.3 -0.739 48.1-169.4 -78.7 130.4 2.8 54.0 10.5 53 258 A L E -GK 39 67B 0 -14,-2.5 -14,-2.4 -2,-0.5 2,-0.4 -0.900 14.3-151.9-126.9 147.0 1.4 53.5 7.0 54 259 A T E -GK 38 66B 18 12,-2.4 12,-2.5 -2,-0.3 2,-0.6 -0.951 29.2-109.3-118.1 144.6 2.7 53.9 3.5 55 260 A V E + K 0 65B 3 -18,-2.7 -19,-2.7 -2,-0.4 10,-0.2 -0.594 39.7 171.8 -68.9 110.4 0.9 54.7 0.3 56 261 A A E - 0 0 37 8,-3.2 2,-0.3 -2,-0.6 9,-0.2 0.733 63.3 -5.3 -91.5 -31.3 1.0 51.4 -1.7 57 262 A E E - K 0 64B 79 7,-1.3 7,-2.7 -23,-0.1 2,-0.4 -0.965 57.2-149.4-163.3 146.5 -1.3 52.3 -4.6 58 263 A V E + K 0 63B 52 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.989 13.5 176.4-123.0 138.3 -3.5 55.1 -5.7 59 264 A C E > - K 0 62B 32 3,-2.5 3,-1.4 -2,-0.4 2,-0.2 -0.837 62.2 -58.0-141.1 103.5 -6.7 54.8 -7.8 60 265 A G T 3 S- 0 0 19 246,-0.4 246,-0.1 -2,-0.3 -29,-0.1 -0.430 121.8 -13.8 64.1-124.0 -8.7 57.9 -8.5 61 266 A Y T 3 S+ 0 0 17 -2,-0.2 19,-2.9 -3,-0.1 20,-0.3 0.097 126.8 82.0 -96.3 19.7 -9.7 59.5 -5.2 62 267 A R E < -KL 59 79B 1 -3,-1.4 -3,-2.5 17,-0.3 2,-0.3 -0.849 56.3-167.1-121.4 161.3 -8.7 56.3 -3.3 63 268 A L E -KL 58 78B 0 15,-2.5 15,-2.5 -2,-0.3 2,-0.5 -0.994 19.1-131.7-147.8 149.4 -5.5 54.8 -2.0 64 269 A R E -KL 57 77B 64 -7,-2.7 -8,-3.2 -2,-0.3 -7,-1.3 -0.924 26.6-152.9-103.1 127.4 -4.3 51.5 -0.6 65 270 A L E -KL 55 76B 0 11,-3.2 11,-1.6 -2,-0.5 2,-0.4 -0.797 3.9-155.5-105.2 144.9 -2.3 51.8 2.6 66 271 A H E -K 54 0B 43 -12,-2.5 -12,-2.4 -2,-0.4 2,-0.8 -0.936 20.0-123.9-121.2 137.9 0.4 49.4 3.8 67 272 A F E > -K 53 0B 11 -2,-0.4 3,-2.3 4,-0.4 -14,-0.2 -0.737 36.2-120.8 -81.6 112.0 1.5 48.8 7.4 68 273 A D T 3 S+ 0 0 8 -16,-1.5 34,-1.0 -2,-0.8 -16,-0.2 -0.252 96.4 16.1 -55.4 127.2 5.3 49.5 7.5 69 274 A G T 3 S+ 0 0 50 1,-0.4 -1,-0.3 32,-0.2 2,-0.1 0.037 112.1 92.5 100.1 -22.2 7.1 46.3 8.6 70 275 A Y S < S- 0 0 77 -3,-2.3 -1,-0.4 1,-0.2 2,-0.0 -0.404 82.6 -74.7-103.9 173.3 4.2 44.0 8.0 71 276 A S > - 0 0 52 -2,-0.1 3,-1.4 1,-0.1 -4,-0.4 -0.310 32.4-124.8 -62.2 148.0 2.8 41.8 5.2 72 277 A E G > S+ 0 0 126 1,-0.2 3,-1.5 2,-0.2 -1,-0.1 0.624 102.8 81.8 -63.7 -18.1 1.1 43.2 2.1 73 278 A C G 3 S+ 0 0 49 1,-0.2 -1,-0.2 799,-0.0 824,-0.1 0.746 87.8 55.2 -63.7 -18.6 -1.9 40.9 3.0 74 279 A H G < S+ 0 0 64 -3,-1.4 -1,-0.2 -7,-0.1 -2,-0.2 0.471 78.5 125.5 -92.7 -1.6 -3.0 43.5 5.6 75 280 A D < - 0 0 29 -3,-1.5 2,-0.3 -4,-0.1 -9,-0.2 -0.218 38.6-171.8 -60.0 148.7 -3.2 46.5 3.1 76 281 A F E -L 65 0B 28 -11,-1.6 -11,-3.2 182,-0.0 2,-0.4 -0.936 18.8-118.0-142.0 158.9 -6.5 48.3 3.0 77 282 A W E +L 64 0B 40 -2,-0.3 2,-0.3 -13,-0.3 -13,-0.2 -0.810 30.0 168.0-101.0 140.7 -8.3 51.0 0.9 78 283 A V E -L 63 0B 18 -15,-2.5 -15,-2.5 -2,-0.4 2,-0.3 -0.923 36.7-103.5-135.0 166.9 -9.5 54.4 2.0 79 284 A N E > -L 62 0B 8 -2,-0.3 3,-2.1 -17,-0.2 -17,-0.3 -0.634 33.7-114.8 -84.8 154.6 -10.7 57.5 0.3 80 285 A A T 3 S+ 0 0 6 -19,-2.9 49,-0.3 1,-0.3 -18,-0.1 0.740 117.6 54.4 -64.3 -21.8 -8.3 60.5 0.1 81 286 A N T 3 S+ 0 0 23 -20,-0.3 -1,-0.3 -58,-0.1 -19,-0.1 0.149 80.0 143.0 -94.4 20.7 -10.7 62.5 2.4 82 287 A S X - 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