==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-JAN-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE/TRANSCRIPTION 05-OCT-10 3P3P . COMPND 2 MOLECULE: HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR M.A.MCDONOUGH,C.J.SCHOFIELD . 354 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16342.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 243 68.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 11 3.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 69 19.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 32 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 42 11.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 68 19.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 1 2 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 1 1 3 2 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A V 0 0 126 0, 0.0 3,-0.3 0, 0.0 2,-0.1 0.000 360.0 360.0 360.0 -4.1 15.4 41.6 8.8 2 10 A A + 0 0 68 1,-0.2 29,-0.2 30,-0.2 30,-0.2 -0.255 360.0 144.8 -99.1 43.8 13.9 41.2 12.2 3 11 A S > - 0 0 86 1,-0.2 3,-0.7 -2,-0.1 2,-0.7 0.748 47.0-148.8 -52.4 -26.3 11.9 38.2 11.0 4 12 A G T 3 - 0 0 9 27,-1.0 250,-0.6 -3,-0.3 -1,-0.2 -0.827 67.0 -20.9 93.1-116.6 12.5 36.8 14.5 5 13 A S T 3 S- 0 0 14 -2,-0.7 251,-0.4 1,-0.4 -1,-0.2 0.289 106.6-107.4-108.1 5.1 12.7 33.0 14.3 6 14 A G < - 0 0 30 -3,-0.7 -1,-0.4 249,-0.1 3,-0.1 -0.184 54.8 -39.1 91.2 171.6 10.9 33.0 10.9 7 15 A E S S- 0 0 89 1,-0.1 13,-0.0 -3,-0.1 -3,-0.0 -0.436 80.3 -83.6 -70.2 142.4 7.4 31.9 10.1 8 16 A P - 0 0 51 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.161 51.6-114.0 -47.8 129.0 6.1 28.8 11.9 9 17 A R - 0 0 45 -3,-0.1 9,-2.0 1,-0.1 2,-0.5 -0.376 24.4-119.2 -68.4 144.5 7.3 25.7 10.0 10 18 A E B -A 17 0A 126 7,-0.2 2,-0.1 8,-0.1 -1,-0.1 -0.759 28.4-127.3 -88.1 123.7 4.6 23.4 8.4 11 19 A E > - 0 0 63 5,-1.8 4,-0.8 -2,-0.5 3,-0.5 -0.417 28.7 -99.9 -72.6 143.9 4.6 19.9 9.8 12 20 A A T 4 S+ 0 0 87 1,-0.2 3,-0.3 2,-0.2 -1,-0.1 -0.252 107.2 35.0 -61.2 147.0 4.8 16.9 7.4 13 21 A G T 4 S- 0 0 69 1,-0.2 -1,-0.2 2,-0.1 -2,-0.1 0.794 127.1 -81.4 76.6 28.5 1.6 15.2 6.5 14 22 A A T 4 S+ 0 0 89 -3,-0.5 -1,-0.2 1,-0.2 -2,-0.2 0.860 80.2 155.4 42.3 46.9 -0.2 18.5 6.6 15 23 A L < - 0 0 141 -4,-0.8 -1,-0.2 -3,-0.3 -3,-0.1 0.132 56.5-109.0 -87.8 22.3 -0.5 18.2 10.4 16 24 A G - 0 0 25 -5,-0.3 -5,-1.8 -6,-0.0 -1,-0.3 -0.083 59.8 -29.5 77.4 177.8 -0.8 22.0 10.6 17 25 A P B -A 10 0A 74 0, 0.0 -7,-0.2 0, 0.0 -8,-0.1 -0.469 54.3-132.1 -69.8 136.0 1.9 24.5 11.9 18 26 A A S S- 0 0 26 -9,-2.0 2,-0.3 -2,-0.2 -8,-0.1 0.892 82.4 -18.9 -52.9 -45.9 4.1 23.1 14.6 19 27 A W - 0 0 8 -10,-0.3 2,-0.3 -3,-0.0 -1,-0.1 -0.845 68.1-132.5-149.4-179.6 3.6 26.1 16.8 20 28 A D > - 0 0 71 -2,-0.3 3,-2.4 1,-0.1 4,-0.3 -0.978 30.4 -99.1-145.3 158.2 2.4 29.7 16.4 21 29 A E G > S+ 0 0 67 -2,-0.3 3,-3.1 1,-0.3 -1,-0.1 0.806 111.6 68.7 -42.5 -46.8 3.5 33.2 17.5 22 30 A S G 3 S+ 0 0 86 1,-0.3 -1,-0.3 -3,-0.0 255,-0.0 0.577 92.0 63.2 -56.0 -8.5 1.1 33.5 20.5 23 31 A Q G < S+ 0 0 27 -3,-2.4 254,-1.9 2,-0.1 2,-0.4 0.572 88.3 86.6 -91.7 -9.3 3.2 30.8 22.2 24 32 A L S < S- 0 0 34 -3,-3.1 2,-0.1 -4,-0.3 252,-0.0 -0.747 80.7-125.1 -93.6 135.9 6.3 33.1 22.2 25 33 A R - 0 0 44 -2,-0.4 2,-0.4 1,-0.1 -2,-0.1 -0.350 29.9-112.5 -72.7 160.0 6.7 35.6 25.0 26 34 A S - 0 0 112 -2,-0.1 2,-0.3 211,-0.0 -1,-0.1 -0.791 34.8-178.7-102.1 140.7 7.2 39.3 24.1 27 35 A Y - 0 0 28 -2,-0.4 210,-0.1 2,-0.2 209,-0.0 -0.933 36.1-122.9-136.1 158.6 10.3 41.3 24.5 28 36 A S S S+ 0 0 68 208,-0.4 -1,-0.0 -2,-0.3 209,-0.0 0.594 85.9 79.9 -74.0 -12.2 11.6 44.9 24.0 29 37 A F S S- 0 0 21 1,-0.0 -2,-0.2 220,-0.0 2,-0.2 -0.631 74.2-122.9-104.0 158.5 14.4 43.8 21.7 30 38 A P - 0 0 68 0, 0.0 222,-1.8 0, 0.0 2,-0.3 -0.580 25.1-166.7 -91.2 157.0 14.7 42.9 18.0 31 39 A T E -b 252 0B 10 220,-0.2 -27,-1.0 -2,-0.2 222,-0.2 -0.991 13.9-149.5-144.7 149.2 16.1 39.6 16.7 32 40 A R E -b 253 0B 36 220,-1.8 222,-2.5 -2,-0.3 -30,-0.2 -0.835 40.0 -95.8-111.8 154.0 17.2 38.3 13.3 33 41 A P E -b 254 0B 53 0, 0.0 222,-0.2 0, 0.0 -28,-0.2 -0.429 26.4-123.5 -78.4 148.5 16.8 34.5 12.6 34 42 A I - 0 0 5 220,-2.4 20,-0.1 -2,-0.1 21,-0.0 -0.699 42.4 -97.8 -83.8 133.4 19.5 31.9 13.1 35 43 A P - 0 0 55 0, 0.0 20,-2.9 0, 0.0 2,-0.9 -0.256 28.0-150.4 -56.0 129.6 20.1 29.9 9.9 36 44 A R E +h 55 0C 84 18,-0.2 20,-0.2 20,-0.1 2,-0.2 -0.881 37.0 162.6-101.0 100.7 18.3 26.5 9.7 37 45 A L E -h 56 0C 19 18,-2.6 20,-2.7 -2,-0.9 2,-0.4 -0.584 40.8 -99.9-117.7 177.9 20.6 24.4 7.5 38 46 A S > - 0 0 27 18,-0.2 3,-2.7 -2,-0.2 6,-0.4 -0.811 28.2-126.0 -99.4 139.0 21.5 20.9 6.5 39 47 A Q T 3 S+ 0 0 70 -2,-0.4 6,-0.1 1,-0.3 -1,-0.1 0.721 116.0 52.4 -52.6 -21.9 24.4 19.1 8.1 40 48 A S T 3 S+ 0 0 87 4,-0.1 -1,-0.3 5,-0.0 3,-0.0 0.557 84.5 107.0 -91.7 -11.9 25.5 18.6 4.5 41 49 A D X> - 0 0 29 -3,-2.7 4,-1.3 1,-0.2 3,-0.6 -0.537 69.4-141.7 -69.6 126.5 25.2 22.3 3.6 42 50 A P H 3> S+ 0 0 105 0, 0.0 4,-2.0 0, 0.0 -1,-0.2 0.867 99.3 63.6 -58.0 -35.4 28.7 23.8 3.4 43 51 A R H 3> S+ 0 0 148 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.879 98.1 53.4 -56.5 -42.9 27.4 27.0 5.0 44 52 A A H <> S+ 0 0 0 -3,-0.6 4,-2.4 -6,-0.4 -1,-0.2 0.960 108.8 47.6 -58.7 -52.2 26.6 25.1 8.3 45 53 A E H X S+ 0 0 50 -4,-1.3 4,-2.2 1,-0.2 -1,-0.2 0.880 111.2 54.7 -55.1 -37.4 30.1 23.8 8.6 46 54 A E H X S+ 0 0 113 -4,-2.0 4,-2.2 1,-0.2 -1,-0.2 0.942 108.4 46.6 -60.5 -51.5 31.2 27.4 7.8 47 55 A L H <>S+ 0 0 20 -4,-2.6 5,-2.9 1,-0.2 -2,-0.2 0.849 111.1 52.3 -60.8 -39.0 29.1 28.8 10.7 48 56 A I H ><5S+ 0 0 1 -4,-2.4 3,-1.2 3,-0.2 -1,-0.2 0.921 111.0 45.4 -67.1 -44.1 30.4 26.2 13.1 49 57 A E H 3<5S+ 0 0 97 -4,-2.2 -2,-0.2 1,-0.3 -1,-0.2 0.892 113.5 51.0 -65.1 -38.1 34.0 26.8 12.4 50 58 A N T 3<5S- 0 0 89 -4,-2.2 -1,-0.3 -5,-0.2 -2,-0.2 0.339 115.3-121.4 -79.1 4.9 33.3 30.6 12.6 51 59 A E T < 5 + 0 0 62 -3,-1.2 -3,-0.2 1,-0.2 -2,-0.1 0.922 65.0 137.6 53.1 52.7 31.7 29.9 16.0 52 60 A E < - 0 0 80 -5,-2.9 -1,-0.2 -6,-0.1 -2,-0.1 -0.978 58.6 -95.9-126.3 140.5 28.3 31.3 15.0 53 61 A P + 0 0 5 0, 0.0 2,-0.3 0, 0.0 212,-0.2 -0.035 46.3 166.5 -52.5 155.8 24.9 29.8 15.8 54 62 A V E - I 0 264C 0 210,-0.7 210,-2.6 -20,-0.1 2,-0.6 -0.866 32.5-132.0-170.9 136.3 23.1 27.5 13.4 55 63 A V E -hI 36 263C 0 -20,-2.9 -18,-2.6 -2,-0.3 2,-0.7 -0.877 19.3-154.2 -96.1 122.8 20.2 25.1 13.6 56 64 A L E -hI 37 262C 2 206,-3.4 206,-1.8 -2,-0.6 3,-0.5 -0.885 7.1-169.2 -98.8 111.5 21.1 21.7 11.9 57 65 A T S S+ 0 0 54 -20,-2.7 -19,-0.2 -2,-0.7 -1,-0.1 0.663 74.8 35.2 -76.6 -17.9 17.8 20.1 10.8 58 66 A D + 0 0 64 -21,-0.4 -1,-0.2 1,-0.1 203,-0.1 -0.242 68.0 115.9-136.2 53.5 19.1 16.6 9.9 59 67 A T - 0 0 2 201,-0.5 102,-0.1 -3,-0.5 -1,-0.1 0.859 56.9-146.9 -87.6 -32.5 21.9 15.3 12.1 60 68 A N > + 0 0 94 200,-0.5 3,-1.2 -3,-0.1 98,-0.3 0.749 47.6 149.5 69.5 22.2 20.1 12.3 13.6 61 69 A L T 3 S+ 0 0 1 1,-0.3 97,-1.6 199,-0.2 98,-0.1 0.926 78.5 16.4 -53.3 -48.7 22.3 13.2 16.5 62 70 A V T >> S+ 0 0 4 95,-0.2 3,-1.5 1,-0.1 4,-0.7 -0.165 83.0 142.7-120.5 40.8 19.7 11.9 19.0 63 71 A Y G X4 S+ 0 0 154 -3,-1.2 3,-1.4 1,-0.3 4,-0.2 0.871 70.9 51.2 -44.3 -53.7 17.6 9.9 16.6 64 72 A P G >4 S+ 0 0 21 0, 0.0 3,-0.6 0, 0.0 -1,-0.3 0.683 105.1 58.2 -61.7 -21.5 16.8 7.1 19.2 65 73 A A G X4 S+ 0 0 0 -3,-1.5 3,-2.5 1,-0.2 -2,-0.2 0.581 78.4 87.7 -87.4 -11.0 15.7 9.6 21.8 66 74 A L G << S+ 0 0 65 -3,-1.4 -1,-0.2 -4,-0.7 -3,-0.1 0.681 85.4 58.1 -63.0 -12.9 13.0 11.1 19.7 67 75 A K G < S+ 0 0 101 -3,-0.6 -1,-0.3 -4,-0.2 5,-0.2 0.434 84.1 116.1 -94.4 -0.4 10.7 8.3 21.1 68 76 A W < + 0 0 6 -3,-2.5 2,-0.3 4,-0.1 3,-0.1 -0.292 30.6 146.3 -69.1 154.3 11.4 9.4 24.7 69 77 A D > - 0 0 51 1,-0.1 4,-2.8 134,-0.0 5,-0.3 -0.924 63.1 -77.7-171.5 172.3 8.6 10.8 26.9 70 78 A L H > S+ 0 0 36 -2,-0.3 4,-3.0 1,-0.2 5,-0.3 0.922 127.7 44.8 -51.0 -52.8 7.7 10.7 30.6 71 79 A E H > S+ 0 0 126 2,-0.2 4,-3.1 1,-0.2 -1,-0.2 0.949 115.4 47.1 -57.8 -52.4 6.4 7.1 30.5 72 80 A Y H > S+ 0 0 45 2,-0.2 4,-1.3 1,-0.2 -2,-0.2 0.936 116.7 43.0 -55.2 -52.0 9.2 5.7 28.5 73 81 A L H >X S+ 0 0 0 -4,-2.8 4,-2.0 2,-0.2 3,-0.9 0.952 115.8 47.4 -61.0 -50.8 11.9 7.4 30.5 74 82 A Q H 3< S+ 0 0 76 -4,-3.0 4,-0.3 -5,-0.3 3,-0.2 0.906 106.9 61.9 -55.3 -41.2 10.3 6.6 33.8 75 83 A E H 3< S- 0 0 130 -4,-3.1 -1,-0.3 -5,-0.3 -2,-0.2 0.816 131.5 -5.3 -55.2 -36.7 9.9 3.0 32.4 76 84 A N H << S+ 0 0 34 -4,-1.3 74,-0.8 -3,-0.9 73,-0.2 0.123 91.7 110.6-155.3 37.2 13.7 2.6 32.2 77 85 A I S < S- 0 0 4 -4,-2.0 70,-0.6 1,-0.3 2,-0.2 0.603 81.3-108.3 -89.0 -11.2 15.8 5.6 33.0 78 86 A G B -P 146 0D 35 -4,-0.3 -1,-0.3 68,-0.3 39,-0.2 -0.560 20.5 -85.1 115.7 179.8 17.2 4.1 36.2 79 87 A N S S+ 0 0 77 66,-0.6 -1,-0.1 -2,-0.2 67,-0.1 0.449 80.6 117.6-108.0 -4.8 16.9 4.5 39.9 80 88 A G S S- 0 0 11 65,-0.5 37,-0.5 -3,-0.2 2,-0.3 0.084 72.7 -90.8 -56.2 174.2 19.4 7.2 40.4 81 89 A D - 0 0 74 35,-0.1 2,-0.5 33,-0.1 35,-0.2 -0.725 34.1-148.0 -93.1 141.7 18.5 10.7 41.8 82 90 A F - 0 0 7 33,-3.8 33,-0.3 -2,-0.3 58,-0.1 -0.937 15.8-125.7-114.8 121.1 17.5 13.5 39.5 83 91 A S - 0 0 15 -2,-0.5 56,-1.3 31,-0.2 2,-0.4 -0.404 34.5-173.7 -60.5 130.4 18.3 17.1 40.3 84 92 A V E -J 138 0C 3 29,-0.8 29,-0.4 54,-0.2 2,-0.4 -0.952 13.1-156.4-138.2 119.0 15.0 19.0 40.1 85 93 A Y E -J 137 0C 22 52,-2.3 52,-1.5 -2,-0.4 2,-0.3 -0.733 10.1-167.5 -95.4 137.5 14.5 22.8 40.4 86 94 A S E +JK 136 111C 26 25,-2.2 25,-1.5 -2,-0.4 2,-0.3 -0.842 10.0 174.7-118.7 157.9 11.2 24.3 41.5 87 95 A A E -JK 135 110C 10 48,-1.6 48,-1.7 -2,-0.3 23,-0.2 -0.979 38.9-137.6-166.0 152.0 10.1 27.9 41.3 88 96 A S S S+ 0 0 89 21,-0.7 -1,-0.1 -2,-0.3 22,-0.1 0.914 93.0 47.5 -74.2 -46.8 7.2 30.3 41.8 89 97 A T S S- 0 0 53 20,-0.3 46,-0.1 2,-0.2 -2,-0.0 -0.253 91.8-109.7 -88.6 177.9 7.9 32.3 38.6 90 98 A H S S+ 0 0 34 96,-0.1 97,-2.9 -2,-0.1 2,-0.6 0.432 94.5 90.2 -87.8 -1.0 8.5 31.1 35.0 91 99 A K B -c 187 0B 52 95,-0.2 2,-1.0 97,-0.1 -2,-0.2 -0.875 58.0-166.0-103.0 118.2 12.1 32.2 35.2 92 100 A F - 0 0 7 95,-3.3 2,-0.3 -2,-0.6 -5,-0.0 -0.636 11.0-166.2-101.7 75.2 14.6 29.6 36.5 93 101 A L - 0 0 44 -2,-1.0 17,-0.3 95,-0.1 16,-0.2 -0.454 19.0-131.0 -64.1 120.1 17.7 31.7 37.3 94 102 A Y - 0 0 33 -2,-0.3 2,-0.4 95,-0.2 137,-0.1 -0.537 25.5-169.4 -74.2 137.4 20.6 29.4 37.7 95 103 A Y - 0 0 10 -2,-0.2 2,-0.8 15,-0.1 133,-0.2 -0.996 23.3-127.6-132.8 135.0 22.7 30.0 40.8 96 104 A D > - 0 0 42 131,-2.7 3,-1.0 -2,-0.4 4,-0.4 -0.724 18.0-162.7 -82.4 112.1 26.1 28.5 41.8 97 105 A E G > S+ 0 0 76 -2,-0.8 3,-2.0 1,-0.2 4,-0.4 0.903 85.6 61.8 -62.8 -43.6 25.7 27.1 45.3 98 106 A K G 3 S+ 0 0 92 1,-0.3 -1,-0.2 2,-0.2 3,-0.2 0.700 108.2 47.3 -57.5 -17.4 29.4 26.8 46.0 99 107 A K G X> S+ 0 0 32 -3,-1.0 4,-0.7 1,-0.2 3,-0.6 0.509 81.3 93.8-101.2 -7.5 29.5 30.6 45.6 100 108 A M T <4 S+ 0 0 53 -3,-2.0 3,-0.2 -4,-0.4 6,-0.2 0.731 74.1 73.1 -57.5 -19.9 26.4 31.4 47.7 101 109 A A T 34 S+ 0 0 72 -4,-0.4 3,-0.3 -3,-0.2 -1,-0.2 0.979 90.9 53.2 -55.9 -60.5 29.0 31.9 50.6 102 110 A N T <4 S+ 0 0 51 -3,-0.6 2,-0.5 1,-0.2 -1,-0.2 0.742 113.6 43.4 -46.6 -36.2 30.2 35.2 49.2 103 111 A F >< + 0 0 47 -4,-0.7 3,-1.2 -3,-0.2 -1,-0.2 -0.733 58.8 170.1-120.5 84.1 26.7 36.7 49.0 104 112 A Q T 3 S+ 0 0 111 -2,-0.5 -1,-0.1 -3,-0.3 -2,-0.1 0.475 76.5 68.4 -69.4 -1.1 24.8 35.9 52.2 105 113 A N T 3 S+ 0 0 162 -3,-0.1 2,-0.6 -5,-0.0 -1,-0.3 0.013 73.3 111.9-106.5 25.2 22.2 38.3 50.9 106 114 A F < - 0 0 45 -3,-1.2 -3,-0.0 -6,-0.2 -6,-0.0 -0.893 51.0-159.9-105.5 119.6 21.1 36.2 48.0 107 115 A K - 0 0 63 -2,-0.6 -2,-0.0 2,-0.0 -3,-0.0 -0.861 22.9-127.3-100.7 108.3 17.6 34.8 48.1 108 116 A P - 0 0 45 0, 0.0 3,-0.1 0, 0.0 -14,-0.1 -0.243 15.9-164.4 -54.5 133.6 17.2 31.8 45.6 109 117 A R S S+ 0 0 53 -16,-0.2 -21,-0.7 1,-0.2 2,-0.4 0.731 81.1 38.9 -89.8 -26.6 14.3 32.1 43.2 110 118 A S E S-K 87 0C 2 -17,-0.3 2,-0.4 -23,-0.2 -1,-0.2 -0.993 75.7-153.2-128.0 129.5 14.5 28.4 42.3 111 119 A N E -K 86 0C 102 -25,-1.5 -25,-2.2 -2,-0.4 2,-0.1 -0.862 10.7-137.1-107.7 136.6 15.3 25.6 44.8 112 120 A R + 0 0 104 -2,-0.4 2,-0.2 -27,-0.2 -27,-0.2 -0.450 21.7 177.1 -86.7 160.7 16.9 22.3 43.9 113 121 A E - 0 0 124 -29,-0.4 -29,-0.8 -2,-0.1 2,-0.1 -0.822 24.0-130.4-167.9 123.4 15.8 18.8 45.1 114 122 A E + 0 0 75 -2,-0.2 2,-0.3 -31,-0.2 -31,-0.2 -0.421 42.1 141.7 -74.0 149.2 17.0 15.3 44.4 115 123 A M - 0 0 15 -33,-0.3 -33,-3.8 -2,-0.1 2,-0.3 -0.980 50.1 -81.9-174.3 171.3 14.4 12.6 43.6 116 124 A K >> - 0 0 68 -2,-0.3 3,-2.5 -35,-0.2 4,-1.8 -0.661 41.1-117.3 -88.2 142.7 13.5 9.6 41.5 117 125 A F H 3> S+ 0 0 4 -37,-0.5 4,-2.7 1,-0.3 5,-0.3 0.897 118.3 55.5 -43.2 -50.7 12.3 10.1 38.0 118 126 A H H 3> S+ 0 0 82 1,-0.3 4,-1.0 2,-0.2 -1,-0.3 0.770 106.6 53.2 -55.7 -26.2 9.0 8.5 39.0 119 127 A E H <> S+ 0 0 77 -3,-2.5 4,-3.0 2,-0.2 5,-0.3 0.910 107.5 48.5 -75.4 -44.2 8.8 11.1 41.7 120 128 A F H X S+ 0 0 1 -4,-1.8 4,-2.5 1,-0.2 -2,-0.2 0.926 110.6 52.0 -59.9 -45.0 9.4 14.0 39.3 121 129 A V H X S+ 0 0 21 -4,-2.7 4,-1.1 -5,-0.2 -1,-0.2 0.800 113.4 45.5 -61.9 -30.7 6.7 12.6 37.0 122 130 A E H X S+ 0 0 109 -4,-1.0 4,-2.9 -5,-0.3 3,-0.3 0.963 112.4 46.7 -76.2 -57.8 4.3 12.4 40.0 123 131 A K H X S+ 0 0 42 -4,-3.0 4,-1.8 1,-0.3 5,-0.2 0.873 117.4 48.0 -51.4 -36.8 5.0 15.9 41.4 124 132 A L H X S+ 0 0 17 -4,-2.5 4,-1.4 -5,-0.3 -1,-0.3 0.829 111.0 49.5 -73.2 -33.6 4.6 17.0 37.8 125 133 A Q H X S+ 0 0 56 -4,-1.1 4,-0.9 -3,-0.3 -2,-0.2 0.797 109.2 53.1 -75.6 -30.2 1.4 15.0 37.4 126 134 A D H >X S+ 0 0 37 -4,-2.9 4,-3.3 2,-0.2 3,-1.3 0.982 111.9 41.3 -68.4 -59.3 -0.1 16.5 40.6 127 135 A I H 3X>S+ 0 0 5 -4,-1.8 5,-1.3 1,-0.3 4,-1.1 0.909 113.2 58.4 -53.2 -41.9 0.4 20.1 39.7 128 136 A Q H 3<5S+ 0 0 61 -4,-1.4 -1,-0.3 -5,-0.2 -2,-0.2 0.761 115.9 33.0 -59.7 -28.5 -0.8 19.1 36.3 129 137 A Q H <<5S+ 0 0 131 -3,-1.3 -2,-0.2 -4,-0.9 -1,-0.2 0.705 120.9 47.2-100.9 -26.5 -4.1 17.9 37.7 130 138 A R H <5S- 0 0 144 -4,-3.3 -2,-0.2 -5,-0.1 -3,-0.2 0.383 105.2-126.4 -94.4 2.7 -4.5 20.3 40.5 131 139 A G T <5 + 0 0 66 -4,-1.1 -3,-0.2 -5,-0.3 -4,-0.1 0.833 43.9 178.9 56.5 37.4 -3.7 23.2 38.2 132 140 A G < - 0 0 28 -5,-1.3 -1,-0.1 -6,-0.2 -2,-0.0 -0.167 35.8-136.3 -67.2 163.3 -1.0 24.5 40.5 133 141 A E S S+ 0 0 87 2,-0.1 -1,-0.1 0, 0.0 -2,-0.0 0.598 71.7 109.3 -94.0 -15.1 1.2 27.6 39.7 134 142 A E - 0 0 74 1,-0.0 2,-0.3 -48,-0.0 -46,-0.2 -0.241 56.0-152.7 -60.6 149.8 4.4 25.9 40.8 135 143 A R E -J 87 0C 50 -48,-1.7 -48,-1.6 -46,-0.1 2,-0.3 -0.921 7.2-161.0-127.4 153.1 6.8 25.0 38.1 136 144 A L E -J 86 0C 4 -2,-0.3 47,-0.9 -50,-0.2 2,-0.3 -0.892 5.7-171.8-130.4 159.9 9.5 22.2 37.8 137 145 A Y E -JL 85 182C 2 -52,-1.5 -52,-2.3 -2,-0.3 2,-0.7 -0.831 13.5-149.5-155.7 111.6 12.6 21.7 35.7 138 146 A L E +JL 84 181C 0 43,-2.8 43,-2.0 -2,-0.3 2,-0.5 -0.749 22.0 169.2 -89.0 118.2 14.6 18.5 35.6 139 147 A Q E + L 0 180C 21 -56,-1.3 2,-0.4 -2,-0.7 41,-0.2 -0.882 15.2 150.0-130.4 98.0 18.3 19.2 34.8 140 148 A Q E - L 0 179C 25 39,-2.0 39,-2.7 -2,-0.5 2,-0.1 -0.992 42.9-123.7-135.2 138.1 20.4 16.1 35.4 141 149 A T E - L 0 178C 54 -2,-0.4 2,-0.9 37,-0.2 37,-0.2 -0.473 36.6-109.3 -74.2 149.2 23.6 14.9 33.8 142 150 A L + 0 0 29 35,-2.0 35,-0.2 -2,-0.1 -1,-0.1 -0.737 51.2 170.0 -86.9 107.2 23.5 11.4 32.3 143 151 A N - 0 0 66 -2,-0.9 -1,-0.1 1,-0.0 3,-0.0 0.435 48.8 -81.6 -87.6-140.1 25.5 9.2 34.6 144 152 A D S S+ 0 0 158 1,-0.1 7,-0.1 7,-0.0 -2,-0.0 0.734 111.6 78.8-102.4 -40.0 26.0 5.4 34.9 145 153 A T S S+ 0 0 76 -67,-0.1 -66,-0.6 -64,-0.1 -65,-0.5 0.397 71.8 133.2 -54.0 7.2 22.9 4.6 36.9 146 154 A V B -P 78 0D 24 -68,-0.2 -68,-0.3 1,-0.1 -69,-0.1 -0.328 62.4-102.9 -66.2 142.0 21.1 4.9 33.6 147 155 A G > - 0 0 13 -70,-0.6 4,-1.6 -71,-0.1 5,-0.1 0.024 29.2-108.7 -57.7 169.0 18.6 2.2 32.5 148 156 A R H > S+ 0 0 83 2,-0.2 4,-1.4 1,-0.2 -1,-0.1 0.911 117.5 43.3 -69.9 -44.7 19.4 -0.5 30.0 149 157 A K H > S+ 0 0 55 -73,-0.2 4,-3.4 2,-0.2 5,-0.2 0.918 112.4 54.0 -67.9 -41.5 17.3 0.8 27.2 150 158 A I H > S+ 0 0 2 -74,-0.8 4,-2.6 1,-0.3 -1,-0.2 0.866 108.4 49.2 -60.1 -36.9 18.5 4.4 27.8 151 159 A V H X S+ 0 0 64 -4,-1.6 4,-1.2 2,-0.2 -1,-0.3 0.827 111.9 51.0 -70.4 -30.6 22.1 3.2 27.5 152 160 A M H >X S+ 0 0 132 -4,-1.4 4,-1.0 2,-0.2 3,-0.6 0.961 111.5 45.2 -68.0 -52.8 21.0 1.4 24.3 153 161 A D H >X S+ 0 0 16 -4,-3.4 3,-1.1 1,-0.3 4,-0.5 0.904 107.7 59.3 -55.9 -44.9 19.4 4.6 22.9 154 162 A F H >< S+ 0 0 43 -4,-2.6 3,-1.0 1,-0.3 -1,-0.3 0.847 102.6 52.9 -53.2 -37.9 22.4 6.6 24.0 155 163 A L H << S+ 0 0 120 -4,-1.2 -1,-0.3 -3,-0.6 4,-0.3 0.762 99.9 64.4 -70.5 -24.6 24.5 4.3 21.7 156 164 A G H << S+ 0 0 40 -3,-1.1 -1,-0.2 -4,-1.0 -93,-0.2 0.601 76.3 112.1 -75.1 -11.9 22.2 5.1 18.9 157 165 A F S << S- 0 0 7 -3,-1.0 2,-1.9 -4,-0.5 3,-0.3 -0.176 86.9-100.7 -57.5 157.5 23.2 8.7 18.9 158 166 A N > + 0 0 43 -97,-1.6 4,-2.0 -98,-0.3 3,-0.3 -0.396 57.3 158.0 -84.3 64.9 25.1 9.8 15.7 159 167 A W H > + 0 0 64 -2,-1.9 4,-3.0 -4,-0.3 5,-0.4 0.833 66.8 67.1 -56.0 -34.6 28.6 9.8 17.3 160 168 A N H > S+ 0 0 122 -3,-0.3 4,-1.8 1,-0.2 -1,-0.2 0.972 109.2 37.0 -50.1 -58.0 30.2 9.4 13.9 161 169 A W H > S+ 0 0 14 -3,-0.3 4,-1.6 2,-0.2 -2,-0.2 0.947 120.3 43.5 -59.6 -57.6 29.0 12.9 13.0 162 170 A I H X S+ 0 0 1 -4,-2.0 4,-2.4 1,-0.2 5,-0.2 0.908 111.4 54.7 -61.1 -40.6 29.4 14.7 16.4 163 171 A N H X S+ 0 0 76 -4,-3.0 4,-1.7 1,-0.2 -1,-0.2 0.907 106.5 52.0 -59.3 -41.0 32.8 13.1 17.0 164 172 A K H X S+ 0 0 72 -4,-1.8 4,-3.2 -5,-0.4 -1,-0.2 0.856 106.8 54.1 -63.4 -33.5 34.0 14.4 13.6 165 173 A Q H X S+ 0 0 0 -4,-1.6 4,-2.7 2,-0.2 6,-0.4 0.959 106.1 51.2 -63.5 -48.7 32.8 17.9 14.7 166 174 A Q H <>S+ 0 0 47 -4,-2.4 5,-0.5 1,-0.2 -1,-0.2 0.839 115.2 45.0 -55.7 -33.5 34.9 17.6 17.8 167 175 A G H ><5S+ 0 0 59 -4,-1.7 3,-0.6 -5,-0.2 -2,-0.2 0.901 112.7 47.1 -79.7 -42.3 37.8 16.7 15.5 168 176 A K H 3<5S+ 0 0 104 -4,-3.2 -2,-0.2 1,-0.2 -3,-0.2 0.875 116.7 44.0 -67.0 -38.1 37.4 19.4 12.9 169 177 A R T 3<5S- 0 0 25 -4,-2.7 -1,-0.2 -5,-0.2 123,-0.2 0.463 104.5-129.0 -86.0 -1.9 36.9 22.1 15.4 170 178 A G T < 5 + 0 0 39 -3,-0.6 -3,-0.2 -5,-0.2 -4,-0.1 0.643 50.2 166.3 63.8 12.9 39.8 20.9 17.5 171 179 A W < - 0 0 20 -5,-0.5 120,-0.2 -6,-0.4 121,-0.1 0.040 34.1-115.4 -53.9 169.6 37.5 21.0 20.5 172 180 A G - 0 0 26 118,-4.2 120,-0.1 1,-0.2 -1,-0.1 0.028 54.7 -44.8 -89.8-156.4 38.4 19.3 23.7 173 181 A Q - 0 0 136 1,-0.1 117,-1.9 116,-0.1 2,-0.8 -0.247 59.8 -96.6 -76.7 162.0 36.6 16.4 25.3 174 182 A L E - M 0 289C 49 115,-0.2 115,-0.3 1,-0.2 -1,-0.1 -0.671 38.0-171.9 -75.1 110.3 32.9 15.9 25.8 175 183 A T E - 0 0 45 113,-2.9 2,-0.3 -2,-0.8 -1,-0.2 0.847 54.7 -39.7 -76.7 -34.7 32.5 17.1 29.3 176 184 A S E - M 0 288C 22 112,-1.1 112,-2.5 -3,-0.1 2,-0.5 -0.996 38.5-117.9-177.4 174.2 28.8 16.0 29.6 177 185 A N E - M 0 287C 11 -2,-0.3 -35,-2.0 110,-0.2 2,-0.4 -0.984 29.7-156.6-129.6 114.9 25.3 15.5 28.4 178 186 A L E -LM 141 286C 4 108,-0.7 108,-1.9 -2,-0.5 2,-0.6 -0.786 4.5-148.6 -97.0 137.3 22.6 17.3 30.3 179 187 A L E -LM 140 285C 1 -39,-2.7 -39,-2.0 -2,-0.4 2,-0.5 -0.919 17.6-173.5-103.3 124.2 19.1 16.0 30.3 180 188 A L E +LM 139 284C 13 104,-2.8 104,-2.2 -2,-0.6 2,-0.4 -0.979 12.0 173.3-123.3 129.2 16.5 18.8 30.5 181 189 A I E +LM 138 283C 0 -43,-2.0 -43,-2.8 -2,-0.5 2,-0.3 -0.975 17.8 171.1-133.3 114.2 12.8 18.2 30.9 182 190 A G E -LM 137 282C 1 100,-1.7 100,-2.2 -2,-0.4 2,-0.3 -0.771 32.7-106.9-124.6 171.1 10.8 21.3 31.5 183 191 A M > - 0 0 31 -47,-0.9 3,-2.7 -2,-0.3 92,-0.3 -0.725 51.6 -85.9 -95.7 144.6 7.2 22.4 31.7 184 192 A E T 3 S+ 0 0 77 -2,-0.3 93,-0.2 1,-0.3 92,-0.2 -0.098 117.3 25.4 -43.5 143.7 5.6 24.5 28.9 185 193 A G T 3 S+ 0 0 1 90,-2.1 -1,-0.3 91,-0.6 92,-0.2 0.147 85.9 142.1 84.8 -22.0 6.4 28.2 29.6 186 194 A N < - 0 0 1 -3,-2.7 89,-2.5 90,-0.2 2,-0.4 -0.237 33.8-157.8 -57.3 141.3 9.5 27.6 31.6 187 195 A V E -cD 91 274B 2 -97,-2.9 -95,-3.3 87,-0.2 87,-0.2 -0.968 18.6-159.3-127.3 137.3 12.3 30.1 31.0 188 196 A T E - D 0 273B 16 85,-3.3 85,-2.1 -2,-0.4 3,-0.1 -0.971 35.9-126.1-109.4 114.6 16.1 29.9 31.5 189 197 A P E - 0 0 20 0, 0.0 -95,-0.2 0, 0.0 82,-0.1 -0.227 39.5 -72.8 -62.8 153.4 17.3 33.5 31.7 190 198 A A E S+ 0 0 1 44,-0.2 42,-2.7 41,-0.1 2,-0.3 -0.150 70.2 141.1 -49.8 127.9 20.0 34.8 29.4 191 199 A H E -ED 231 271B 7 80,-1.7 80,-2.6 40,-0.3 2,-0.4 -0.931 41.5-125.5-156.6 171.1 23.5 33.5 30.3 192 200 A Y E - D 0 270B 4 38,-1.5 2,-0.3 -2,-0.3 78,-0.2 -0.976 17.0-146.2-128.5 143.2 26.6 32.3 28.6 193 201 A D - 0 0 6 76,-0.6 75,-2.8 -2,-0.4 160,-0.2 -0.773 16.8-130.2-106.5 154.6 28.4 29.0 29.1 194 202 A E S S+ 0 0 3 158,-2.7 97,-0.4 -2,-0.3 2,-0.3 0.173 82.4 66.6 -90.7 19.3 32.2 28.5 28.9 195 203 A Q S S- 0 0 9 157,-0.2 2,-0.3 95,-0.1 73,-0.2 -0.908 88.5 -96.7-136.6 164.2 32.0 25.5 26.6 196 204 A Q E -N 289 0C 2 93,-2.8 93,-2.9 -2,-0.3 2,-0.4 -0.604 46.2-162.3 -77.6 135.8 30.9 24.5 23.1 197 205 A N E -NO 288 265C 5 68,-1.6 68,-2.5 -2,-0.3 2,-0.7 -0.979 24.7-163.0-132.1 133.8 27.4 23.1 23.1 198 206 A F E -NO 287 264C 0 89,-2.1 89,-1.3 -2,-0.4 2,-0.9 -0.947 20.3-158.5-111.5 105.6 25.3 21.1 20.7 199 207 A F E -NO 286 263C 8 64,-2.8 64,-2.9 -2,-0.7 2,-0.7 -0.774 7.6-167.2 -90.7 99.2 21.7 21.5 21.9 200 208 A A E -NO 285 262C 0 85,-1.9 85,-2.2 -2,-0.9 62,-0.2 -0.803 10.8-144.4 -97.7 109.1 19.6 18.6 20.6 201 209 A Q E +N 284 0C 0 60,-2.6 59,-2.2 -2,-0.7 83,-0.2 -0.442 25.7 166.9 -71.8 136.9 15.9 19.1 20.8 202 210 A I E + 0 0 3 81,-3.0 2,-0.4 1,-0.4 82,-0.2 0.776 59.1 11.2-117.4 -51.8 13.8 15.9 21.6 203 211 A K E S+N 283 0C 82 80,-1.8 80,-2.6 56,-0.1 -1,-0.4 -0.999 107.2 0.0-138.5 139.5 10.3 16.7 22.6 204 212 A G S S- 0 0 10 -2,-0.4 2,-0.4 78,-0.2 78,-0.1 -0.164 87.6 -67.6 78.8-178.4 8.2 19.9 22.5 205 213 A Y - 0 0 45 74,-0.2 71,-2.1 75,-0.2 2,-0.4 -0.929 39.3-168.4-119.4 139.2 9.4 23.2 21.2 206 214 A K E -FG 257 275B 1 51,-2.2 51,-2.8 -2,-0.4 2,-0.6 -0.981 14.9-142.7-125.6 132.9 11.9 25.7 22.6 207 215 A R E -FG 256 274B 20 67,-2.8 67,-1.8 -2,-0.4 2,-0.6 -0.822 19.0-160.5 -94.7 123.0 12.6 29.3 21.6 208 216 A C E -FG 255 273B 0 47,-3.4 47,-1.0 -2,-0.6 2,-0.6 -0.915 9.7-173.3-112.2 119.1 16.3 30.1 21.6 209 217 A I E -FG 254 272B 0 63,-2.9 63,-1.8 -2,-0.6 2,-0.3 -0.930 13.7-174.4-111.7 109.8 17.4 33.7 21.8 210 218 A L E -FG 253 271B 0 43,-3.0 43,-2.8 -2,-0.6 61,-0.3 -0.739 10.8-162.9-106.0 152.7 21.2 34.1 21.4 211 219 A F E - G 0 270B 0 59,-2.1 59,-2.4 -2,-0.3 41,-0.1 -0.994 26.0-111.4-133.4 139.2 23.5 37.1 21.7 212 220 A P > - 0 0 11 0, 0.0 3,-2.1 0, 0.0 39,-0.1 -0.295 29.3-110.6 -69.5 155.5 27.1 37.5 20.5 213 221 A P G > S+ 0 0 15 0, 0.0 3,-1.0 0, 0.0 55,-0.0 0.826 114.3 67.5 -51.0 -36.0 30.0 37.8 22.9 214 222 A D G 3 S+ 0 0 103 1,-0.3 3,-0.3 2,-0.1 55,-0.0 0.338 84.2 72.1 -71.5 7.4 30.5 41.4 21.9 215 223 A Q G X> + 0 0 24 -3,-2.1 3,-1.5 1,-0.2 4,-1.0 0.029 59.9 118.7-110.0 28.0 27.2 42.4 23.5 216 224 A F H <> S+ 0 0 45 -3,-1.0 4,-0.9 1,-0.3 3,-0.3 0.841 70.4 55.6 -57.9 -39.1 28.7 42.0 26.9 217 225 A E H 34 S+ 0 0 126 -3,-0.3 29,-0.3 1,-0.2 -1,-0.3 0.492 108.2 48.8 -77.1 -3.4 28.1 45.6 27.8 218 226 A C H <4 S+ 0 0 10 -3,-1.5 -1,-0.2 29,-0.1 -2,-0.2 0.580 110.7 48.4-106.7 -18.7 24.4 45.3 27.0 219 227 A L H < S- 0 0 0 -4,-1.0 14,-0.8 -3,-0.3 15,-0.7 0.553 86.8-151.9-101.8 -7.8 23.7 42.2 29.0 220 228 A Y < - 0 0 46 -4,-0.9 13,-1.8 12,-0.2 14,-0.1 0.870 13.2-148.7 39.1 69.0 25.4 43.2 32.3 221 229 A P B -Q 232 0E 18 0, 0.0 11,-0.2 0, 0.0 8,-0.1 -0.227 22.5 -99.9 -61.8 155.2 26.5 39.8 33.7 222 230 A Y B -r 229 0F 47 9,-1.8 8,-0.5 6,-0.5 11,-0.0 -0.222 57.0 -74.7 -65.5 165.0 26.5 39.4 37.5 223 231 A P > - 0 0 58 0, 0.0 3,-1.8 0, 0.0 -1,-0.2 -0.316 44.6-113.8 -62.0 148.2 30.0 39.7 39.2 224 232 A V T 3 S+ 0 0 3 1,-0.3 5,-0.2 5,-0.1 -2,-0.1 0.810 116.8 49.1 -53.3 -33.7 32.2 36.7 38.7 225 233 A H T 3 S+ 0 0 30 100,-0.1 -1,-0.3 3,-0.1 -123,-0.2 0.529 90.7 101.1 -86.5 -4.9 32.1 35.9 42.4 226 234 A H S X S- 0 0 17 -3,-1.8 3,-1.6 1,-0.1 -130,-0.1 -0.439 83.5-118.9 -77.6 150.9 28.3 36.2 42.6 227 235 A P T 3 S+ 0 0 0 0, 0.0 -131,-2.7 0, 0.0 -1,-0.1 0.880 114.8 56.8 -57.4 -36.1 26.2 33.0 42.6 228 236 A C T > S+ 0 0 0 -133,-0.2 3,-2.3 -129,-0.1 -6,-0.5 0.083 80.6 160.9 -85.0 28.6 24.5 34.1 39.4 229 237 A D B < +r 222 0F 6 -3,-1.6 -5,-0.1 1,-0.3 3,-0.1 -0.213 64.5 18.1 -52.5 133.2 27.9 34.3 37.7 230 238 A R T 3 S+ 0 0 9 -8,-0.5 -38,-1.5 1,-0.3 -1,-0.3 0.299 101.5 111.2 85.6 -7.3 27.5 34.3 33.9 231 239 A Q B < S-E 191 0B 0 -3,-2.3 -9,-1.8 -40,-0.2 -1,-0.3 -0.626 75.0-109.1 -94.0 157.4 23.8 35.2 34.0 232 240 A S B -Q 221 0E 6 -42,-2.7 -12,-0.2 -11,-0.2 -13,-0.0 -0.638 14.6-149.6 -82.2 141.6 22.5 38.6 32.8 233 241 A Q + 0 0 61 -13,-1.8 2,-0.2 -14,-0.8 -1,-0.1 0.704 69.4 104.4 -83.0 -20.3 21.3 40.8 35.6 234 242 A V S S- 0 0 9 -15,-0.7 2,-1.0 -14,-0.1 -44,-0.2 -0.408 71.2-138.1 -65.6 129.1 18.7 42.3 33.2 235 243 A D > - 0 0 61 3,-0.4 3,-1.1 -2,-0.2 -1,-0.1 -0.782 11.7-159.1 -88.7 100.7 15.2 41.1 33.8 236 244 A F T 3 S+ 0 0 14 -2,-1.0 -208,-0.4 1,-0.3 -1,-0.2 0.789 90.1 54.6 -49.5 -34.1 13.9 40.6 30.2 237 245 A D T 3 S+ 0 0 61 1,-0.3 -1,-0.3 -210,-0.1 -2,-0.0 0.847 130.1 13.9 -71.4 -33.7 10.3 40.8 31.3 238 246 A N S < S- 0 0 122 -3,-1.1 -3,-0.4 2,-0.0 -1,-0.3 -0.569 83.5-160.3-143.4 76.4 10.9 44.2 32.9 239 247 A P - 0 0 19 0, 0.0 2,-1.4 0, 0.0 -3,-0.1 -0.369 13.4-139.8 -63.1 124.5 14.3 45.7 31.8 240 248 A D > - 0 0 60 -2,-0.2 4,-2.9 1,-0.2 3,-0.3 -0.676 21.7-179.2 -87.6 88.4 15.7 48.3 34.1 241 249 A Y T 4 S+ 0 0 79 -2,-1.4 -1,-0.2 1,-0.2 7,-0.1 0.649 75.7 63.7 -65.4 -15.9 17.0 50.8 31.6 242 250 A E T 4 S+ 0 0 145 2,-0.2 -1,-0.2 1,-0.1 -2,-0.1 0.957 116.8 26.5 -71.2 -49.5 18.3 53.1 34.3 243 251 A R T 4 S+ 0 0 157 -3,-0.3 -2,-0.2 1,-0.2 -1,-0.1 0.805 134.9 37.0 -80.2 -31.5 20.8 50.6 35.7 244 252 A F >< + 0 0 10 -4,-2.9 3,-2.2 1,-0.2 -1,-0.2 -0.390 67.2 156.9-122.2 56.2 21.2 48.8 32.3 245 253 A P G > S+ 0 0 56 0, 0.0 3,-1.8 0, 0.0 -1,-0.2 0.836 70.8 59.2 -47.2 -47.1 21.0 51.5 29.6 246 254 A N G > S+ 0 0 61 1,-0.3 3,-1.7 -29,-0.3 -5,-0.1 0.520 80.8 85.8 -67.3 -2.0 22.9 49.6 27.0 247 255 A F G X S+ 0 0 3 -3,-2.2 3,-0.7 1,-0.3 -1,-0.3 0.620 79.5 67.8 -71.8 -9.2 20.3 46.9 27.1 248 256 A Q G < S+ 0 0 115 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.370 94.6 54.9 -88.1 3.3 18.5 49.1 24.6 249 257 A N G < S+ 0 0 104 -3,-1.7 2,-0.3 -31,-0.1 -1,-0.2 0.189 82.6 127.8-117.2 12.7 21.1 48.4 22.0 250 258 A V < + 0 0 2 -3,-0.7 2,-0.4 -32,-0.1 -3,-0.1 -0.534 31.7 177.5 -80.9 133.3 20.7 44.6 22.3 251 259 A V - 0 0 66 -2,-0.3 2,-0.2 -222,-0.1 -220,-0.2 -0.972 8.4-170.3-135.1 117.7 20.1 42.5 19.2 252 260 A G E -b 31 0B 0 -222,-1.8 -220,-1.8 -2,-0.4 2,-0.5 -0.681 23.4-125.8-110.2 163.4 19.7 38.8 19.4 253 261 A Y E -bF 32 210B 83 -43,-2.8 -43,-3.0 -222,-0.2 2,-0.3 -0.908 38.6-166.3-102.2 129.5 19.5 35.9 16.9 254 262 A E E +bF 33 209B 8 -222,-2.5 -220,-2.4 -250,-0.6 2,-0.3 -0.757 19.6 153.1-122.6 165.4 16.4 33.8 17.4 255 263 A T E - F 0 208B 1 -47,-1.0 -47,-3.4 -2,-0.3 2,-0.5 -0.953 35.0-123.5-174.2 160.0 14.9 30.4 16.5 256 264 A V E - F 0 207B 0 -251,-0.4 2,-0.3 -2,-0.3 -49,-0.2 -0.968 27.0-154.5-118.8 115.2 12.5 27.7 17.6 257 265 A V E - F 0 206B 0 -51,-2.8 -51,-2.2 -2,-0.5 3,-0.1 -0.710 13.6-175.7 -90.9 141.8 13.9 24.2 17.8 258 266 A G > - 0 0 2 -2,-0.3 3,-2.7 -53,-0.2 -57,-0.3 -0.754 45.1 -48.9-125.7 174.0 11.7 21.2 17.5 259 267 A P T 3 S+ 0 0 58 0, 0.0 -57,-0.2 0, 0.0 -1,-0.1 -0.172 127.5 19.9 -45.6 122.7 12.2 17.4 17.8 260 268 A G T 3 S+ 0 0 20 -59,-2.2 -201,-0.5 1,-0.3 -200,-0.5 0.197 95.0 118.4 101.0 -16.9 15.2 16.5 15.7 261 269 A D < - 0 0 11 -3,-2.7 -60,-2.6 -203,-0.1 2,-0.5 -0.614 46.3-158.0 -87.4 146.2 16.9 19.9 15.5 262 270 A V E -IO 56 200C 1 -206,-1.8 -206,-3.4 -2,-0.3 2,-0.6 -0.989 5.3-158.2-125.0 120.6 20.3 20.5 16.9 263 271 A L E -IO 55 199C 0 -64,-2.9 -64,-2.8 -2,-0.5 2,-0.7 -0.887 11.4-141.8-100.4 122.0 21.3 24.1 17.7 264 272 A Y E -IO 54 198C 0 -210,-2.6 -210,-0.7 -2,-0.6 -66,-0.2 -0.759 15.5-168.5 -83.9 116.1 24.9 24.9 17.9 265 273 A I E - O 0 197C 3 -68,-2.5 -68,-1.6 -2,-0.7 3,-0.1 -0.894 19.4-138.4-105.9 100.5 25.4 27.4 20.7 266 274 A P > - 0 0 2 0, 0.0 3,-1.9 0, 0.0 -73,-0.2 -0.210 33.2 -86.2 -57.7 148.5 29.0 28.7 20.3 267 275 A M T 3 S+ 0 0 17 1,-0.3 -73,-0.2 -73,-0.1 -71,-0.1 -0.222 113.4 15.2 -54.3 143.4 31.0 29.0 23.5 268 276 A Y T 3 S+ 0 0 7 -75,-2.8 2,-0.3 1,-0.2 -1,-0.3 0.377 91.9 131.9 71.5 -5.6 30.5 32.4 25.3 269 277 A W < - 0 0 23 -3,-1.9 -76,-0.6 -76,-0.2 -1,-0.2 -0.636 59.5-122.4 -79.0 136.6 27.4 33.2 23.3 270 278 A W E -DG 192 211B 2 -59,-2.4 -59,-2.1 -2,-0.3 2,-0.3 -0.523 32.2-173.3 -76.1 145.5 24.5 34.3 25.5 271 279 A H E -DG 191 210B 6 -80,-2.6 -80,-1.7 -61,-0.3 2,-0.4 -0.998 17.8-166.3-144.3 143.3 21.3 32.3 25.2 272 280 A H E - G 0 209B 3 -63,-1.8 -63,-2.9 -2,-0.3 2,-0.4 -0.993 19.5-165.9-124.0 128.4 17.9 32.7 26.6 273 281 A I E +DG 188 208B 10 -85,-2.1 -85,-3.3 -2,-0.4 2,-0.4 -0.980 11.0 175.3-131.2 131.9 15.7 29.6 26.4 274 282 A E E -DG 187 207B 3 -67,-1.8 -67,-2.8 -2,-0.4 2,-0.5 -0.986 28.5-132.0-135.1 142.6 12.0 29.1 26.8 275 283 A S E - G 0 206B 2 -89,-2.5 -90,-2.1 -2,-0.4 -69,-0.2 -0.808 49.4 -98.3 -88.9 125.2 9.5 26.2 26.4 276 284 A L > - 0 0 2 -71,-2.1 3,-1.6 -2,-0.5 -91,-0.6 -0.039 40.1-100.9 -48.2 144.0 6.6 27.5 24.4 277 285 A L T 3 S+ 0 0 49 -254,-1.9 -1,-0.1 1,-0.3 -93,-0.0 -0.472 105.8 0.8 -66.8 133.6 3.5 28.5 26.3 278 286 A N T 3 S+ 0 0 130 -2,-0.2 -1,-0.3 1,-0.1 -2,-0.1 0.751 100.3 120.0 57.5 25.9 0.8 25.8 26.2 279 287 A G S < S- 0 0 31 -3,-1.6 -74,-0.2 1,-0.3 -2,-0.1 0.386 72.8-121.0-100.2 3.3 3.3 23.7 24.1 280 288 A G - 0 0 27 -4,-0.2 -1,-0.3 -76,-0.1 -75,-0.2 -0.237 53.0 -31.2 84.5-178.7 3.5 20.8 26.6 281 289 A I - 0 0 32 -98,-0.2 2,-0.3 -97,-0.1 -98,-0.2 -0.330 62.3-140.6 -71.2 157.0 6.6 19.5 28.3 282 290 A T E -M 182 0C 1 -100,-2.2 -100,-1.7 -78,-0.1 2,-0.4 -0.902 11.5-164.1-121.7 149.0 10.0 19.8 26.6 283 291 A I E +MN 181 203C 0 -80,-2.6 -81,-3.0 -2,-0.3 -80,-1.8 -0.999 15.3 163.4-134.0 134.1 12.9 17.4 26.4 284 292 A T E -MN 180 201C 0 -104,-2.2 -104,-2.8 -2,-0.4 2,-0.4 -0.988 20.5-160.5-147.2 148.6 16.4 18.3 25.3 285 293 A V E -MN 179 200C 0 -85,-2.2 -85,-1.9 -2,-0.3 2,-0.3 -0.999 17.8-164.3-129.5 125.2 19.8 16.7 25.7 286 294 A N E -MN 178 199C 4 -108,-1.9 -108,-0.7 -2,-0.4 2,-0.4 -0.717 11.5-142.2-110.4 165.6 22.8 18.9 25.2 287 295 A F E -MN 177 198C 0 -89,-1.3 -89,-2.1 -2,-0.3 2,-0.5 -0.997 13.8-157.2-125.1 126.8 26.4 18.0 24.6 288 296 A W E -MN 176 197C 7 -112,-2.5 -113,-2.9 -2,-0.4 -112,-1.1 -0.925 11.4-178.8-112.0 127.6 29.2 20.0 26.2 289 297 A Y E -MN 174 196C 1 -93,-2.9 -93,-2.8 -2,-0.5 -115,-0.2 -0.978 32.1-116.6-126.0 134.4 32.7 20.2 24.8 290 298 A K - 0 0 40 -117,-1.9 -118,-4.2 -2,-0.4 -95,-0.1 -0.428 46.6-111.1 -61.9 137.9 35.8 22.1 26.1 291 299 A G - 0 0 19 -97,-0.4 -118,-0.1 -120,-0.2 -1,-0.1 -0.143 40.6 -78.3 -68.2 169.4 36.7 24.6 23.5 292 300 A A - 0 0 51 -123,-0.2 -121,-0.2 -121,-0.1 -1,-0.1 -0.333 58.7 -98.7 -64.9 151.3 39.8 24.3 21.4 293 301 A P - 0 0 111 0, 0.0 -1,-0.1 0, 0.0 55,-0.0 -0.281 48.0 -79.1 -71.4 158.6 43.0 25.5 23.1 294 302 A T - 0 0 67 1,-0.1 4,-0.1 50,-0.1 54,-0.0 -0.345 54.7-110.9 -59.9 129.7 44.6 29.0 22.7 295 303 A P - 0 0 78 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.123 31.7 -97.6 -61.1 156.6 46.6 29.3 19.4 296 304 A K S S+ 0 0 89 1,-0.2 2,-0.6 2,-0.0 -2,-0.0 0.905 110.9 15.4 -36.8 -77.9 50.4 29.6 19.4 297 305 A R S S- 0 0 91 0, 0.0 2,-0.6 0, 0.0 -1,-0.2 -0.922 85.4-130.3-107.2 121.3 50.6 33.4 19.0 298 306 A I - 0 0 21 -2,-0.6 4,-0.1 -3,-0.1 -2,-0.0 -0.595 26.2-139.7 -73.4 117.3 47.4 35.2 19.8 299 307 A E - 0 0 77 -2,-0.6 -1,-0.1 2,-0.1 0, 0.0 -0.100 31.5 -73.0 -68.6 172.3 46.7 37.6 16.9 300 308 A Y S S+ 0 0 172 2,-0.1 2,-0.2 0, 0.0 -1,-0.1 -0.926 98.0 30.9-131.2 153.8 45.4 41.2 17.3 301 309 A P S S- 0 0 116 0, 0.0 -2,-0.1 0, 0.0 2,-0.0 0.696 92.6-114.0 -76.1 174.0 43.1 42.8 18.0 302 310 A L - 0 0 30 -2,-0.2 2,-0.1 1,-0.1 -2,-0.1 -0.273 22.7-113.4 -72.0 156.3 41.5 40.3 20.3 303 311 A K >> - 0 0 66 1,-0.1 4,-1.5 -3,-0.0 3,-0.8 -0.480 34.5-106.1 -81.4 160.4 38.2 38.6 19.6 304 312 A A H 3> S+ 0 0 33 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.887 118.0 53.2 -58.2 -40.9 35.3 39.5 21.9 305 313 A H H 3> S+ 0 0 47 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.758 104.4 57.0 -69.4 -20.2 35.3 36.2 23.9 306 314 A Q H <> S+ 0 0 20 -3,-0.8 4,-2.4 2,-0.2 -1,-0.2 0.905 107.1 47.9 -73.7 -41.7 39.0 36.6 24.6 307 315 A K H X S+ 0 0 117 -4,-1.5 4,-3.2 2,-0.2 5,-0.2 0.920 110.7 51.3 -62.7 -43.6 38.3 40.0 26.2 308 316 A V H X S+ 0 0 7 -4,-2.2 4,-2.5 1,-0.2 -1,-0.2 0.893 109.3 51.6 -60.8 -37.5 35.5 38.5 28.2 309 317 A A H X S+ 0 0 2 -4,-1.7 4,-2.2 2,-0.2 -1,-0.2 0.912 111.2 47.9 -63.6 -43.1 37.9 35.8 29.3 310 318 A I H X S+ 0 0 44 -4,-2.4 4,-2.8 2,-0.2 5,-0.2 0.967 110.8 49.2 -61.6 -56.0 40.3 38.4 30.4 311 319 A M H X S+ 0 0 69 -4,-3.2 4,-2.3 1,-0.2 5,-0.2 0.926 110.5 52.1 -50.3 -48.4 37.8 40.4 32.3 312 320 A R H X S+ 0 0 5 -4,-2.5 4,-1.7 1,-0.2 -1,-0.2 0.919 111.3 46.9 -55.4 -45.2 36.6 37.3 34.1 313 321 A N H X S+ 0 0 28 -4,-2.2 4,-2.8 33,-0.3 -1,-0.2 0.889 107.5 55.4 -67.1 -39.2 40.2 36.5 35.1 314 322 A I H X S+ 0 0 60 -4,-2.8 4,-2.5 1,-0.2 5,-0.2 0.936 108.8 49.1 -58.0 -45.7 40.9 40.0 36.3 315 323 A E H X S+ 0 0 39 -4,-2.3 4,-1.3 -5,-0.2 -1,-0.2 0.860 111.4 48.7 -61.7 -37.4 37.9 39.7 38.6 316 324 A K H X S+ 0 0 48 -4,-1.7 4,-1.6 -5,-0.2 -1,-0.2 0.899 110.6 51.5 -69.3 -41.6 39.0 36.4 40.0 317 325 A M H X S+ 0 0 103 -4,-2.8 4,-3.2 1,-0.2 3,-0.5 0.952 110.2 47.1 -59.2 -52.8 42.6 37.7 40.6 318 326 A L H X S+ 0 0 31 -4,-2.5 4,-2.0 1,-0.2 6,-0.4 0.817 107.9 59.6 -59.5 -30.7 41.3 40.7 42.6 319 327 A G H < S+ 0 0 5 -4,-1.3 -1,-0.2 -5,-0.2 5,-0.2 0.892 114.2 33.9 -65.4 -39.8 39.1 38.3 44.5 320 328 A E H >< S+ 0 0 103 -4,-1.6 3,-1.2 -3,-0.5 -2,-0.2 0.928 118.3 50.5 -80.4 -50.4 42.1 36.3 45.7 321 329 A A H 3< S+ 0 0 87 -4,-3.2 -3,-0.2 1,-0.3 -2,-0.2 0.909 112.5 47.2 -54.9 -46.0 44.6 39.1 46.0 322 330 A L T 3< S- 0 0 46 -4,-2.0 -1,-0.3 -5,-0.3 -2,-0.2 0.603 105.0-132.9 -72.9 -11.0 42.3 41.2 48.1 323 331 A G S < S+ 0 0 66 -3,-1.2 -3,-0.2 -4,-0.1 -2,-0.1 0.472 83.6 63.7 72.7 0.2 41.5 38.2 50.2 324 332 A N S > S- 0 0 58 -6,-0.4 3,-2.4 -5,-0.2 4,-0.3 -0.766 71.5-143.9-163.2 114.2 37.8 39.0 49.9 325 333 A P G > S+ 0 0 26 0, 0.0 3,-1.3 0, 0.0 4,-0.5 0.716 97.3 64.5 -42.5 -36.4 35.5 39.1 46.8 326 334 A Q G 3 S+ 0 0 103 1,-0.3 3,-0.1 2,-0.2 -7,-0.1 0.648 92.8 60.4 -72.4 -13.1 33.4 42.0 48.1 327 335 A E G <> S+ 0 0 92 -3,-2.4 4,-2.2 1,-0.2 -1,-0.3 0.496 85.0 84.2 -89.4 -3.7 36.4 44.4 47.9 328 336 A V H <> S+ 0 0 11 -3,-1.3 4,-2.8 -4,-0.3 5,-0.2 0.977 87.8 48.2 -61.5 -56.8 36.6 43.8 44.2 329 337 A G H > S+ 0 0 32 -4,-0.5 4,-2.9 1,-0.2 5,-0.2 0.935 112.6 48.5 -49.6 -54.5 34.0 46.4 43.2 330 338 A P H > S+ 0 0 74 0, 0.0 4,-2.7 0, 0.0 -1,-0.2 0.896 112.4 47.7 -54.8 -44.6 35.5 49.1 45.4 331 339 A L H X S+ 0 0 64 -4,-2.2 4,-1.6 1,-0.2 -2,-0.2 0.936 113.0 49.1 -64.5 -43.4 39.0 48.5 44.1 332 340 A L H X S+ 0 0 56 -4,-2.8 4,-1.5 1,-0.2 5,-0.2 0.897 113.1 47.0 -60.9 -42.8 37.7 48.6 40.6 333 341 A N H X S+ 0 0 86 -4,-2.9 4,-2.9 -5,-0.2 3,-0.2 0.916 109.6 52.2 -65.3 -44.1 35.8 51.8 41.2 334 342 A T H < S+ 0 0 111 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.803 108.2 56.3 -60.6 -29.9 38.8 53.5 42.9 335 343 A M H < S+ 0 0 84 -4,-1.6 -1,-0.2 -5,-0.2 -2,-0.2 0.857 120.8 22.1 -71.4 -40.2 40.8 52.5 39.8 336 344 A I H >X>S+ 0 0 68 -4,-1.5 3,-3.8 -3,-0.2 4,-2.4 0.838 87.0 110.6-101.1 -36.1 38.6 54.2 37.2 337 345 A K T 3<5S- 0 0 136 -4,-2.9 -4,-0.0 1,-0.3 0, 0.0 -0.164 105.1 -7.5 -47.3 111.6 36.6 56.9 39.0 338 346 A G T 345S+ 0 0 72 1,-0.1 -1,-0.3 3,-0.1 -2,-0.1 0.555 134.5 65.6 77.5 8.7 38.1 60.1 37.6 339 347 A R T <45S+ 0 0 158 -3,-3.8 -2,-0.2 0, 0.0 -3,-0.1 0.636 116.7 5.9-126.7 -41.2 40.8 58.3 35.8 340 348 A Y T <5 0 0 181 -4,-2.4 -3,-0.1 0, 0.0 -4,-0.1 0.512 360.0 360.0-124.9 -11.3 39.3 56.2 33.0 341 349 A N < 0 0 130 -5,-1.2 -3,-0.1 0, 0.0 0, 0.0 -0.621 360.0 360.0-103.1 360.0 35.6 57.0 33.0 342 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 343 199 B L 0 0 166 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 140.2 49.9 37.4 30.3 344 200 B E + 0 0 77 1,-0.2 4,-0.3 4,-0.0 -50,-0.1 0.297 360.0 78.8 62.6 -14.4 48.0 35.2 27.8 345 201 B D S S+ 0 0 129 2,-0.1 -1,-0.2 1,-0.1 0, 0.0 0.192 91.6 59.6 -94.5 5.3 47.8 33.1 31.0 346 202 B L S S+ 0 0 31 1,-0.0 -33,-0.3 -33,-0.0 -1,-0.1 0.820 99.9 45.4 -99.2 -49.7 45.2 35.9 31.1 347 203 B I S S+ 0 0 10 -34,-0.1 -37,-0.1 -35,-0.1 -2,-0.1 0.519 88.1 107.9 -78.9 -5.3 43.0 35.2 28.1 348 204 B N - 0 0 62 -4,-0.3 -35,-0.1 1,-0.1 2,-0.1 -0.389 59.5-147.2 -70.2 153.5 42.8 31.5 28.7 349 205 B S - 0 0 46 1,-0.2 2,-0.1 -155,-0.0 -1,-0.1 -0.187 6.8-133.3-107.7-160.9 39.4 30.3 30.0 350 206 B H - 0 0 115 -156,-0.1 -1,-0.2 -2,-0.1 -41,-0.0 -0.181 28.4-106.5-128.1-139.3 37.8 27.8 32.3 351 207 B A + 0 0 40 -2,-0.1 2,-0.5 -61,-0.1 -156,-0.1 -0.235 49.2 151.0-163.2 63.1 34.9 25.4 31.8 352 208 B D + 0 0 44 2,-0.0 -158,-2.7 -157,-0.0 2,-0.3 -0.880 12.5 170.5-106.8 129.0 31.7 26.5 33.7 353 209 B V - 0 0 20 -2,-0.5 2,-2.9 -160,-0.2 -160,-0.1 -0.880 50.8 -88.2-129.7 160.7 28.2 25.6 32.4 354 210 B N 0 0 10 -2,-0.3 -161,-0.0 1,-0.1 -2,-0.0 -0.346 360.0 360.0 -70.0 67.0 24.7 25.9 34.0 355 211 B A 0 0 60 -2,-2.9 -1,-0.1 -261,-0.0 -2,-0.1 -0.623 360.0 360.0-135.1 360.0 24.9 22.5 35.7