==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-JAN-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 13-OCT-10 3P8E . COMPND 2 MOLECULE: N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR M.LLUIS,Y.WANG,A.F.MONZINGO,W.FAST,J.D.ROBERTUS . 544 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 23630.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 388 71.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 58 10.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 50 9.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 8 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 63 11.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 83 15.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 109 20.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 2 0 2 0 0 3 0 2 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 2 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 4 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A A > 0 0 109 0, 0.0 3,-1.4 0, 0.0 216,-0.1 0.000 360.0 360.0 360.0 125.6 -14.1 15.3 5.0 2 10 A F T 3 + 0 0 46 1,-0.2 3,-0.1 214,-0.1 124,-0.0 -0.329 360.0 8.9 -67.7 132.5 -15.7 17.6 2.3 3 11 A G T 3 S+ 0 0 22 1,-0.3 214,-5.0 213,-0.1 2,-0.6 0.676 86.4 145.1 76.9 17.8 -14.8 17.1 -1.3 4 12 A R < + 0 0 73 -3,-1.4 2,-0.3 212,-0.3 -1,-0.3 -0.807 22.2 170.3 -88.5 121.3 -13.0 13.8 -0.6 5 13 A A - 0 0 6 -2,-0.6 266,-0.3 212,-0.5 3,-0.1 -0.943 30.9-178.9-132.2 152.5 -13.4 11.4 -3.5 6 14 A T S S+ 0 0 43 264,-3.1 46,-2.7 -2,-0.3 2,-0.3 0.566 74.4 27.3-117.3 -22.4 -12.0 8.1 -4.5 7 15 A H E -aB 52 270A 39 263,-2.2 263,-2.4 44,-0.2 2,-0.3 -0.874 57.2-161.8-137.4 164.4 -13.8 7.4 -7.8 8 16 A A E -aB 53 269A 0 44,-1.9 46,-2.3 -2,-0.3 2,-0.6 -0.943 11.3-146.4-152.3 132.2 -15.5 9.3 -10.6 9 17 A V E +aB 54 268A 0 259,-2.6 259,-1.8 -2,-0.3 2,-0.2 -0.897 30.0 161.8 -98.8 123.7 -18.0 8.2 -13.3 10 18 A V E -a 55 0A 0 44,-2.1 46,-2.5 -2,-0.6 2,-0.3 -0.766 21.8-147.3-128.2 175.0 -17.6 9.9 -16.6 11 19 A R E -a 56 0A 12 55,-0.4 57,-0.1 255,-0.3 44,-0.1 -0.987 19.8-111.8-153.5 137.0 -18.8 9.1 -20.1 12 20 A A - 0 0 26 44,-2.3 47,-0.3 -2,-0.3 23,-0.0 -0.344 34.5-119.1 -68.9 145.7 -17.5 9.6 -23.6 13 21 A L - 0 0 8 45,-0.1 45,-0.2 52,-0.1 2,-0.1 -0.663 25.1-127.5 -86.8 142.7 -19.3 12.0 -25.8 14 22 A P > - 0 0 1 0, 0.0 3,-1.4 0, 0.0 4,-0.3 -0.434 19.8-115.5 -83.0 162.2 -20.8 10.7 -29.1 15 23 A E T > S+ 0 0 116 1,-0.3 3,-0.8 2,-0.2 4,-0.5 0.804 113.4 69.2 -64.6 -28.1 -20.2 12.3 -32.5 16 24 A S T 3> S+ 0 0 20 1,-0.2 4,-3.0 2,-0.2 5,-0.3 0.579 79.5 81.0 -67.0 -9.9 -23.9 13.1 -32.6 17 25 A L H <> S+ 0 0 1 -3,-1.4 4,-2.4 3,-0.2 -1,-0.2 0.939 82.4 58.1 -65.9 -47.9 -23.3 15.7 -29.8 18 26 A G H <4 S+ 0 0 4 -3,-0.8 11,-0.5 -4,-0.3 -1,-0.2 0.848 125.3 20.4 -51.0 -39.9 -22.0 18.5 -32.0 19 27 A Q H 4 S+ 0 0 142 -4,-0.5 -1,-0.2 -3,-0.1 -2,-0.2 0.735 133.7 36.7 -99.8 -28.7 -25.2 18.4 -34.1 20 28 A H H < S+ 0 0 125 -4,-3.0 2,-0.2 -5,-0.1 -3,-0.2 0.548 80.4 110.5-112.6 -9.3 -27.7 16.8 -31.9 21 29 A A S < S- 0 0 2 -4,-2.4 43,-0.0 -5,-0.3 41,-0.0 -0.496 74.0-106.1 -74.4 134.5 -27.1 17.8 -28.2 22 30 A L + 0 0 60 -2,-0.2 2,-0.2 1,-0.1 -1,-0.1 -0.185 57.3 142.8 -54.3 148.7 -29.7 20.1 -26.6 23 31 A R 0 0 92 -3,-0.1 236,-0.1 237,-0.0 -1,-0.1 -0.640 360.0 360.0-156.8-148.6 -28.6 23.7 -26.2 24 32 A S 0 0 115 234,-0.5 138,-0.0 -2,-0.2 236,-0.0 -0.727 360.0 360.0-178.1 360.0 -29.8 27.4 -26.4 25 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 26 35 A G 0 0 113 0, 0.0 3,-0.1 0, 0.0 232,-0.0 0.000 360.0 360.0 360.0 177.7 -24.2 29.8 -30.9 27 36 A E - 0 0 134 1,-0.1 2,-0.3 3,-0.0 3,-0.0 -0.047 360.0 -90.2 -54.7 161.2 -21.1 28.7 -32.8 28 37 A E - 0 0 93 1,-0.1 2,-0.4 333,-0.0 -1,-0.1 -0.611 49.5-112.0 -66.9 136.4 -20.8 25.4 -34.5 29 38 A V - 0 0 6 -11,-0.5 2,-0.8 -2,-0.3 3,-0.1 -0.584 16.3-140.6 -72.1 128.7 -19.4 22.8 -32.1 30 39 A D > - 0 0 2 -2,-0.4 4,-2.0 1,-0.2 5,-0.2 -0.832 16.5-170.7 -85.2 110.2 -15.9 21.5 -32.9 31 40 A V H > S+ 0 0 17 -2,-0.8 4,-2.6 2,-0.2 -1,-0.2 0.839 84.0 55.0 -72.8 -34.0 -16.3 17.8 -31.9 32 41 A A H > S+ 0 0 23 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.944 112.1 45.0 -61.3 -46.0 -12.6 17.1 -32.3 33 42 A R H > S+ 0 0 76 2,-0.2 4,-2.6 1,-0.2 -2,-0.2 0.878 113.0 48.0 -65.7 -42.8 -11.9 19.9 -29.9 34 43 A A H X S+ 0 0 1 -4,-2.0 4,-2.6 2,-0.2 5,-0.3 0.942 110.1 55.8 -63.2 -45.1 -14.5 18.9 -27.4 35 44 A E H X S+ 0 0 70 -4,-2.6 4,-1.6 2,-0.2 -2,-0.2 0.940 110.5 42.4 -47.0 -62.9 -13.2 15.4 -27.6 36 45 A R H >X S+ 0 0 30 -4,-2.4 4,-2.2 1,-0.2 3,-1.0 0.955 112.7 54.0 -47.7 -59.3 -9.7 16.4 -26.7 37 46 A Q H 3X S+ 0 0 12 -4,-2.6 4,-2.5 1,-0.3 -1,-0.2 0.834 108.5 48.5 -49.3 -43.1 -10.9 18.7 -23.9 38 47 A H H 3X S+ 0 0 5 -4,-2.6 4,-1.7 2,-0.2 -1,-0.3 0.796 108.5 55.8 -70.8 -28.7 -12.9 16.0 -22.3 39 48 A Q H X S+ 0 0 35 -4,-2.2 4,-2.4 1,-0.2 3,-0.6 0.935 110.4 55.4 -55.2 -48.6 -7.8 16.3 -20.6 41 50 A Y H 3X S+ 0 0 0 -4,-2.5 4,-1.4 1,-0.3 -1,-0.2 0.837 107.6 49.0 -52.2 -39.5 -10.7 16.6 -18.1 42 51 A V H 3X S+ 0 0 17 -4,-1.7 4,-2.5 -3,-0.3 5,-0.3 0.807 109.7 51.9 -72.4 -29.6 -10.6 12.9 -17.5 43 52 A G H S+ 0 0 24 -4,-1.6 5,-3.0 -3,-0.6 4,-0.8 0.866 103.0 56.9 -79.2 -38.2 -6.9 12.8 -16.9 44 53 A V H <>S+ 0 0 19 -4,-2.4 5,-1.8 3,-0.2 6,-0.2 0.971 116.4 36.6 -54.9 -53.9 -6.9 15.6 -14.4 45 54 A L H <5S+ 0 0 0 -4,-1.4 6,-2.1 3,-0.2 -2,-0.2 0.915 133.4 25.9 -63.5 -45.4 -9.3 13.6 -12.2 46 55 A G H X5S+ 0 0 19 -4,-2.5 4,-0.6 4,-0.2 -3,-0.2 0.946 133.2 23.6 -90.2 -58.9 -7.8 10.2 -13.0 47 56 A S T <5S+ 0 0 109 -4,-0.8 -3,-0.2 -5,-0.3 -4,-0.1 0.985 131.3 35.4 -74.0 -59.9 -4.2 10.5 -13.9 48 57 A K T 4 - 0 0 58 3,-0.3 3,-2.3 -47,-0.3 6,-0.3 -0.913 1.9-160.3 -98.6 107.7 -24.0 6.1 -27.0 60 69 A E T 3 S+ 0 0 94 -2,-0.8 -1,-0.2 1,-0.3 5,-0.1 0.899 92.0 66.2 -50.1 -41.7 -24.3 7.8 -30.4 61 70 A S T 3 S+ 0 0 86 1,-0.2 -1,-0.3 -3,-0.1 -3,-0.0 0.754 101.3 49.9 -49.0 -32.2 -28.0 7.4 -29.8 62 71 A L X - 0 0 10 -3,-2.3 3,-2.2 1,-0.1 -3,-0.3 -0.799 65.9-176.6-115.3 89.3 -27.8 9.8 -26.8 63 72 A P T 3 S+ 0 0 23 0, 0.0 3,-0.3 0, 0.0 -42,-0.2 0.687 85.1 50.9 -63.8 -14.5 -25.9 13.0 -27.9 64 73 A D T > S+ 0 0 8 1,-0.2 3,-1.9 -44,-0.1 25,-0.0 0.453 75.4 109.8 -99.3 0.5 -26.1 14.4 -24.4 65 74 A C T < + 0 0 1 -3,-2.2 -1,-0.2 -6,-0.3 -52,-0.1 0.640 61.9 71.8 -55.9 -25.1 -24.8 11.3 -22.6 66 75 A V T 3 S+ 0 0 0 -3,-0.3 2,-2.0 1,-0.2 -55,-0.4 0.792 78.0 80.3 -62.2 -31.1 -21.4 12.9 -21.6 67 76 A F X + 0 0 7 -3,-1.9 3,-0.9 1,-0.2 4,-0.3 -0.504 58.3 165.3 -81.2 75.9 -23.0 15.1 -19.0 68 77 A V G >> + 0 0 4 -2,-2.0 3,-1.3 1,-0.2 4,-0.7 0.692 58.2 73.6 -73.4 -23.2 -23.2 12.4 -16.4 69 78 A E G >4 S+ 0 0 18 196,-2.6 3,-1.0 1,-0.3 -1,-0.2 0.885 88.1 63.7 -59.4 -36.8 -23.9 14.6 -13.4 70 79 A D G <4 S+ 0 0 12 -3,-0.9 49,-0.7 195,-0.4 -1,-0.3 0.740 100.8 51.8 -60.0 -22.7 -27.5 15.2 -14.6 71 80 A V G <4 S+ 0 0 3 -3,-1.3 11,-2.5 -4,-0.3 2,-0.3 0.644 114.1 26.7 -94.9 -15.4 -28.4 11.5 -14.2 72 81 A A E << -C 81 0B 5 -3,-1.0 2,-0.4 -4,-0.7 9,-0.2 -0.979 49.9-160.0-153.1 139.0 -27.2 10.8 -10.6 73 82 A V E -C 80 0B 17 7,-2.4 7,-4.1 -2,-0.3 2,-0.4 -0.957 21.0-166.8-110.1 135.5 -26.7 12.4 -7.3 74 83 A V E +C 79 0B 30 -2,-0.4 2,-0.4 5,-0.2 5,-0.2 -0.980 12.6 172.9-129.5 131.3 -24.4 10.5 -4.9 75 84 A C E > -C 78 0B 9 3,-2.5 3,-2.2 -2,-0.4 2,-0.3 -0.954 63.7 -45.0-143.6 118.9 -23.9 11.2 -1.2 76 85 A E T 3 S- 0 0 82 -2,-0.4 195,-0.3 1,-0.3 0, 0.0 -0.441 125.8 -19.5 58.6-118.6 -21.9 8.9 1.1 77 86 A E T 3 S+ 0 0 112 -2,-0.3 29,-3.0 28,-0.1 2,-0.5 0.256 118.2 99.5-101.3 13.6 -22.9 5.4 0.2 78 87 A T E < -Cd 75 106B 32 -3,-2.2 -3,-2.5 27,-0.2 2,-0.6 -0.889 52.2-163.3-114.9 120.3 -26.2 6.4 -1.5 79 88 A A E -Cd 74 107B 0 27,-4.7 29,-2.5 -2,-0.5 2,-0.7 -0.854 2.5-162.7 -98.3 118.4 -26.8 6.8 -5.2 80 89 A L E -Cd 73 108B 0 -7,-4.1 -7,-2.4 -2,-0.6 2,-0.7 -0.906 7.0-158.2 -94.5 117.7 -29.8 8.7 -6.4 81 90 A I E -Cd 72 109B 3 27,-3.1 29,-2.9 -2,-0.7 -9,-0.3 -0.885 25.2-142.9 -93.3 116.1 -30.5 7.8 -10.0 82 91 A T - 0 0 4 -11,-2.5 36,-0.1 -2,-0.7 34,-0.1 -0.011 15.7-125.6 -80.7 174.8 -32.5 10.7 -11.3 83 92 A R - 0 0 43 34,-0.2 34,-1.7 26,-0.1 7,-0.1 -0.798 40.8-135.5-116.6 87.5 -35.4 11.2 -13.7 84 93 A P - 0 0 0 0, 0.0 34,-0.2 0, 0.0 6,-0.1 -0.016 6.5-129.7 -50.2 136.3 -34.0 13.9 -16.1 85 94 A G S S+ 0 0 17 4,-0.1 3,-0.1 51,-0.1 33,-0.1 0.863 94.9 76.1 -53.1 -43.6 -36.2 16.8 -17.0 86 95 A A S > S- 0 0 9 1,-0.2 3,-1.2 3,-0.0 4,-0.3 -0.637 77.2-149.9 -72.8 111.2 -35.4 16.3 -20.7 87 96 A P G > S+ 0 0 93 0, 0.0 3,-1.7 0, 0.0 4,-0.2 0.895 92.9 56.8 -48.2 -45.4 -37.5 13.2 -21.7 88 97 A S G > S+ 0 0 81 1,-0.3 3,-0.7 2,-0.1 -3,-0.0 0.785 98.7 60.4 -63.1 -27.3 -35.0 12.1 -24.4 89 98 A R G X S+ 0 0 5 -3,-1.2 3,-1.3 1,-0.2 -1,-0.3 0.398 77.6 91.0 -82.1 1.5 -32.1 11.9 -21.9 90 99 A R G X S+ 0 0 67 -3,-1.7 3,-1.7 -4,-0.3 4,-0.5 0.801 72.6 67.9 -71.3 -28.0 -33.8 9.2 -19.7 91 100 A K G < S+ 0 0 147 -3,-0.7 4,-0.4 1,-0.3 -1,-0.3 0.455 87.5 72.7 -67.7 -0.5 -32.2 6.3 -21.5 92 101 A E G <> S+ 0 0 5 -3,-1.3 4,-0.6 2,-0.1 -1,-0.3 0.559 83.5 66.8 -87.1 -11.8 -28.9 7.5 -20.1 93 102 A V H X> S+ 0 0 22 -3,-1.7 4,-2.8 2,-0.2 3,-0.8 0.890 85.9 69.6 -75.3 -42.0 -29.8 6.3 -16.6 94 103 A D H 3> S+ 0 0 90 -4,-0.5 4,-1.6 1,-0.3 3,-0.2 0.893 103.8 40.9 -35.7 -63.2 -29.7 2.6 -17.6 95 104 A M H 3> S+ 0 0 53 -4,-0.4 4,-1.3 1,-0.2 -1,-0.3 0.701 113.8 53.7 -68.1 -22.8 -25.9 2.5 -18.1 96 105 A M H X S+ 0 0 96 -4,-1.6 4,-1.8 -5,-0.2 3,-0.6 0.948 111.4 44.4 -44.6 -59.1 -25.1 -0.6 -13.9 99 108 A A H 3X S+ 0 0 4 -4,-1.3 4,-1.6 1,-0.3 -1,-0.2 0.879 111.2 51.8 -58.7 -44.8 -21.9 1.2 -12.9 100 109 A L H 3<>S+ 0 0 0 -4,-2.4 5,-1.8 1,-0.2 -1,-0.3 0.689 108.5 54.5 -70.1 -17.4 -23.2 2.5 -9.6 101 110 A E H X<5S+ 0 0 97 -4,-1.3 3,-1.6 -3,-0.6 -1,-0.2 0.851 103.5 53.2 -81.0 -36.6 -24.2 -1.1 -8.9 102 111 A K H 3<5S+ 0 0 150 -4,-1.8 -2,-0.2 1,-0.3 -1,-0.1 0.848 102.2 60.3 -61.8 -34.0 -20.6 -2.3 -9.6 103 112 A L T 3<5S- 0 0 13 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.421 113.5-123.3 -76.1 5.3 -19.5 0.3 -7.1 104 113 A Q T < 5 + 0 0 175 -3,-1.6 2,-0.2 1,-0.2 -3,-0.2 0.871 57.8 158.4 55.2 38.1 -21.6 -1.6 -4.5 105 114 A L < - 0 0 16 -5,-1.8 2,-0.5 1,-0.1 -1,-0.2 -0.622 51.3-103.5 -92.7 150.2 -23.5 1.7 -3.9 106 115 A N E -d 78 0B 100 -29,-3.0 -27,-4.7 -2,-0.2 2,-0.4 -0.629 44.2-151.8 -71.2 122.1 -27.0 2.0 -2.4 107 116 A I E +d 79 0B 45 -2,-0.5 2,-0.4 -29,-0.2 -27,-0.2 -0.800 22.0 177.8-100.9 137.3 -29.3 2.7 -5.3 108 117 A V E -d 80 0B 58 -29,-2.5 -27,-3.1 -2,-0.4 2,-0.5 -0.986 17.7-150.9-130.3 128.9 -32.5 4.7 -5.3 109 118 A E E -d 81 0B 84 -2,-0.4 2,-1.6 -29,-0.2 3,-0.2 -0.870 12.1-139.2-101.0 123.3 -34.3 5.2 -8.6 110 119 A M + 0 0 7 -29,-2.9 7,-0.1 -2,-0.5 5,-0.0 -0.634 44.1 151.1 -74.6 88.6 -36.5 8.3 -9.1 111 120 A K + 0 0 156 -2,-1.6 -1,-0.2 -28,-0.0 4,-0.1 0.657 21.2 125.0 -96.2 -20.6 -39.2 6.4 -11.0 112 121 A D > - 0 0 45 -3,-0.2 3,-2.6 1,-0.2 32,-0.0 -0.205 59.1-141.5 -46.6 112.8 -42.2 8.7 -10.0 113 122 A E T 3 S+ 0 0 154 1,-0.3 -1,-0.2 -2,-0.1 -3,-0.0 0.456 99.1 49.3 -64.3 -4.0 -43.7 9.7 -13.4 114 123 A N T 3 S+ 0 0 113 26,-0.1 2,-0.6 24,-0.0 -1,-0.3 0.177 95.0 96.1-114.5 12.9 -44.4 13.3 -12.2 115 124 A A < + 0 0 0 -3,-2.6 2,-0.4 25,-0.2 22,-0.0 -0.911 45.7 173.3-115.2 114.0 -40.9 13.7 -10.8 116 125 A T + 0 0 22 -2,-0.6 22,-2.2 -34,-0.1 25,-0.3 -0.923 4.8 165.7-114.8 149.2 -38.1 15.4 -12.8 117 126 A L - 0 0 0 -34,-1.7 2,-0.4 -2,-0.4 -34,-0.2 -0.899 19.2-160.6-161.5 126.1 -34.6 16.1 -11.4 118 127 A D > - 0 0 0 -2,-0.3 3,-1.2 -34,-0.2 -48,-0.2 -0.901 20.8-140.6-101.6 140.9 -31.3 17.1 -13.0 119 128 A G G > S+ 0 0 1 -49,-0.7 3,-2.3 -2,-0.4 -49,-0.2 0.808 102.7 72.1 -66.1 -28.6 -28.2 16.6 -11.0 120 129 A G G 3 S+ 0 0 4 1,-0.3 46,-1.9 45,-0.1 -1,-0.2 0.741 94.6 54.7 -55.1 -23.5 -27.1 20.0 -12.5 121 130 A D G < S+ 0 0 0 -3,-1.2 11,-2.1 44,-0.2 2,-0.7 0.428 90.0 92.0 -91.7 1.2 -29.7 21.5 -10.2 122 131 A V E < -E 131 0C 5 -3,-2.3 2,-0.6 9,-0.2 9,-0.2 -0.855 50.3-173.2-108.5 113.8 -28.3 20.0 -7.0 123 132 A L E -E 130 0C 3 7,-3.2 7,-3.0 -2,-0.7 2,-0.6 -0.908 6.1-166.4 -97.9 120.1 -25.8 21.9 -4.8 124 133 A F E -E 129 0C 57 -2,-0.6 5,-0.2 5,-0.2 47,-0.1 -0.922 6.9-174.4-109.4 110.7 -24.5 19.8 -2.0 125 134 A T - 0 0 0 3,-1.8 50,-0.5 -2,-0.6 4,-0.1 0.585 45.6-113.4 -80.2 -13.0 -22.6 22.0 0.5 126 135 A G S S+ 0 0 22 2,-0.6 -1,-0.1 48,-0.1 3,-0.1 -0.033 116.7 57.9 99.9 -29.3 -21.4 19.1 2.7 127 136 A R S S- 0 0 88 1,-0.2 26,-0.5 25,-0.0 2,-0.3 0.602 121.5 -27.6-100.0 -22.6 -23.7 20.4 5.4 128 137 A E - 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