==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=3-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 31-MAR-07 2PD5 . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.STEUBER,A.HEINE,G.KLEBE . 315 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13783.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 202 64.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 35 11.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 13 4.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 42 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 27.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 2 1 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 2 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 126 0, 0.0 13,-0.1 0, 0.0 3,-0.0 0.000 360.0 360.0 360.0 137.8 7.3 38.7 -18.5 2 2 A S + 0 0 61 11,-0.1 12,-2.8 12,-0.1 13,-0.4 0.678 360.0 45.7 -90.4 -19.4 9.4 37.0 -15.8 3 3 A R E -A 13 0A 132 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.889 61.4-142.7-132.3 159.2 6.8 34.8 -14.1 4 4 A I E -A 12 0A 40 8,-2.8 8,-3.0 -2,-0.3 2,-0.4 -0.944 29.0-113.5-119.8 136.5 4.0 32.4 -14.8 5 5 A L E -A 11 0A 108 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.551 29.6-152.6 -72.8 123.1 0.8 32.1 -12.9 6 6 A L > - 0 0 4 4,-2.9 3,-2.0 -2,-0.4 198,-0.1 -0.574 28.8-108.9 -90.2 162.3 0.4 28.8 -11.0 7 7 A N T 3 S+ 0 0 78 1,-0.3 171,-0.1 196,-0.2 -1,-0.1 0.457 117.9 62.4 -74.4 1.0 -3.0 27.2 -10.1 8 8 A N T 3 S- 0 0 59 2,-0.2 -1,-0.3 169,-0.1 3,-0.1 0.325 120.2-108.2-100.1 6.0 -2.4 28.1 -6.4 9 9 A G S < S+ 0 0 58 -3,-2.0 2,-0.2 1,-0.3 -2,-0.1 0.391 81.9 122.2 84.0 -2.8 -2.4 31.9 -7.4 10 10 A A - 0 0 15 144,-0.1 -4,-2.9 95,-0.1 2,-0.4 -0.544 61.1-123.8 -86.1 158.9 1.4 32.3 -6.8 11 11 A K E -A 5 0A 93 -6,-0.2 -6,-0.2 -2,-0.2 -8,-0.0 -0.897 20.1-156.8-107.4 134.6 3.7 33.5 -9.6 12 12 A M E -A 4 0A 1 -8,-3.0 -8,-2.8 -2,-0.4 2,-0.2 -0.943 21.2-119.1-111.0 128.1 6.7 31.3 -10.6 13 13 A P E -A 3 0A 11 0, 0.0 -10,-0.3 0, 0.0 -11,-0.1 -0.476 16.2-144.4 -62.3 132.0 9.9 32.8 -12.2 14 14 A I S S+ 0 0 23 -12,-2.8 245,-2.8 -2,-0.2 2,-0.5 0.591 86.3 59.2 -78.5 -11.9 10.3 31.2 -15.6 15 15 A L B +b 259 0B 4 -13,-0.4 25,-0.6 243,-0.2 26,-0.6 -0.953 69.6 163.3-118.4 116.5 14.1 31.3 -15.3 16 16 A G E -c 41 0B 0 243,-3.1 2,-0.6 -2,-0.5 26,-0.3 -0.876 37.2-107.5-129.3 168.4 15.6 29.4 -12.4 17 17 A L E -c 42 0B 2 24,-2.6 26,-2.9 -2,-0.3 245,-0.2 -0.815 27.5-144.0 -98.4 123.3 19.0 28.1 -11.3 18 18 A G E -cd 43 262B 6 243,-2.2 245,-0.7 -2,-0.6 26,-0.1 -0.536 14.2-174.6 -81.6 150.7 19.6 24.3 -11.3 19 19 A T > + 0 0 1 24,-0.6 3,-1.6 -2,-0.2 2,-0.3 0.303 36.4 126.8-131.5 4.8 21.8 22.7 -8.6 20 20 A W T 3 S+ 0 0 63 1,-0.3 28,-0.1 23,-0.1 29,-0.1 -0.608 88.2 8.2 -68.6 124.4 22.2 19.0 -9.5 21 21 A K T 3 S+ 0 0 52 -2,-0.3 -1,-0.3 1,-0.3 28,-0.0 0.396 90.9 134.9 83.1 3.0 25.9 18.3 -9.5 22 22 A S < - 0 0 4 -3,-1.6 -1,-0.3 241,-0.1 5,-0.1 -0.702 57.2-128.5 -79.1 115.1 26.9 21.6 -8.1 23 23 A P >> - 0 0 55 0, 0.0 4,-2.8 0, 0.0 3,-2.4 -0.234 12.6-121.2 -62.5 150.9 29.5 20.7 -5.4 24 24 A P H 3> S+ 0 0 62 0, 0.0 4,-0.8 0, 0.0 26,-0.1 0.868 114.5 69.1 -55.9 -29.9 28.9 22.1 -1.9 25 25 A G H 34 S+ 0 0 71 1,-0.2 4,-0.0 2,-0.1 -3,-0.0 0.526 118.9 14.3 -61.2 -13.9 32.3 23.7 -2.5 26 26 A Q H <> S+ 0 0 91 -3,-2.4 4,-2.7 2,-0.1 5,-0.2 0.346 104.4 81.5-139.4 -16.9 30.8 26.0 -5.2 27 27 A V H X S+ 0 0 0 -4,-2.8 4,-2.6 2,-0.2 5,-0.2 0.891 91.2 57.5 -69.7 -28.1 27.0 26.0 -5.0 28 28 A T H X S+ 0 0 24 -4,-0.8 4,-2.0 -5,-0.2 -1,-0.2 0.961 112.0 41.5 -60.6 -52.8 27.1 28.5 -2.1 29 29 A E H > S+ 0 0 100 2,-0.2 4,-2.4 1,-0.2 5,-0.3 0.850 113.1 55.8 -59.5 -39.3 29.0 30.9 -4.4 30 30 A A H X S+ 0 0 1 -4,-2.7 4,-2.9 1,-0.2 5,-0.2 0.935 109.6 44.3 -60.9 -44.9 26.7 30.0 -7.3 31 31 A V H X S+ 0 0 0 -4,-2.6 4,-2.7 -5,-0.2 5,-0.2 0.933 110.8 53.8 -69.4 -38.2 23.6 30.9 -5.6 32 32 A K H X S+ 0 0 42 -4,-2.0 4,-2.1 -5,-0.2 -2,-0.2 0.947 114.5 42.4 -60.7 -44.2 25.0 34.2 -4.2 33 33 A V H X S+ 0 0 38 -4,-2.4 4,-2.2 2,-0.2 5,-0.2 0.924 112.1 53.6 -68.5 -42.1 26.0 35.2 -7.7 34 34 A A H X>S+ 0 0 0 -4,-2.9 5,-2.5 -5,-0.3 4,-1.2 0.954 110.9 45.9 -59.0 -46.5 22.8 34.1 -9.2 35 35 A I H <5S+ 0 0 1 -4,-2.7 3,-0.4 -5,-0.2 -1,-0.2 0.925 110.2 55.6 -60.1 -42.3 20.8 36.1 -6.7 36 36 A D H <5S+ 0 0 89 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.815 111.3 42.8 -61.7 -34.7 23.1 39.1 -7.3 37 37 A V H <5S- 0 0 63 -4,-2.2 -1,-0.2 -3,-0.2 -2,-0.2 0.543 132.1 -80.2 -95.7 -5.9 22.4 39.0 -11.1 38 38 A G T <5S+ 0 0 20 -4,-1.2 -3,-0.2 -3,-0.4 -4,-0.1 0.425 76.3 140.9 138.0 -8.7 18.6 38.5 -10.9 39 39 A Y < + 0 0 0 -5,-2.5 -1,-0.3 -6,-0.2 -23,-0.1 -0.380 12.5 167.2 -64.5 138.3 17.8 34.8 -10.3 40 40 A R + 0 0 68 -25,-0.6 33,-3.4 1,-0.2 2,-0.5 0.410 57.9 69.1-123.5 -8.8 14.9 34.4 -8.0 41 41 A H E -ce 16 73B 1 -26,-0.6 -24,-2.6 31,-0.2 2,-0.4 -0.962 57.2-174.3-120.5 127.4 14.1 30.7 -8.5 42 42 A I E -ce 17 74B 1 31,-1.7 33,-2.5 -2,-0.5 2,-0.6 -0.989 15.0-147.4-124.6 127.0 16.4 28.0 -7.3 43 43 A D E +ce 18 75B 3 -26,-2.9 -24,-0.6 -2,-0.4 2,-0.2 -0.899 30.5 167.6 -96.9 118.4 15.7 24.4 -8.2 44 44 A C - 0 0 0 31,-2.1 2,-0.3 -2,-0.6 3,-0.1 -0.728 18.2-169.5-120.9 170.0 16.9 22.0 -5.4 45 45 A A > - 0 0 0 -2,-0.2 3,-1.2 31,-0.2 5,-0.5 -0.940 32.0-128.8-160.9 145.7 16.6 18.4 -4.2 46 46 A H G > S+ 0 0 17 31,-1.0 3,-1.9 -2,-0.3 5,-0.2 0.908 112.6 58.7 -53.9 -40.3 17.5 16.3 -1.1 47 47 A I G 3 S+ 0 0 31 1,-0.3 -1,-0.3 30,-0.3 74,-0.0 0.724 89.9 69.3 -70.2 -15.8 19.2 13.9 -3.5 48 48 A Y G < S- 0 0 38 -3,-1.2 -1,-0.3 1,-0.1 -27,-0.2 0.601 92.9-148.7 -75.5 -9.0 21.5 16.7 -4.8 49 49 A Q S < S+ 0 0 106 -3,-1.9 -3,-0.1 -4,-0.3 -2,-0.1 0.775 74.5 89.4 47.1 42.8 23.1 16.5 -1.3 50 50 A N > + 0 0 0 -5,-0.5 4,-2.2 -4,-0.1 3,-0.2 0.108 42.2 114.1-144.2 14.4 23.9 20.2 -1.3 51 51 A E H > S+ 0 0 3 1,-0.2 4,-2.5 -6,-0.2 5,-0.1 0.889 74.4 58.7 -65.6 -34.6 20.8 21.8 0.2 52 52 A N H > S+ 0 0 62 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.933 108.2 46.1 -57.5 -42.9 22.6 23.0 3.3 53 53 A E H > S+ 0 0 57 2,-0.2 4,-1.5 -3,-0.2 -2,-0.2 0.833 110.1 51.8 -76.0 -32.4 25.0 25.0 1.1 54 54 A V H X S+ 0 0 0 -4,-2.2 4,-2.1 1,-0.2 3,-0.3 0.963 109.7 52.8 -58.4 -47.7 22.2 26.4 -1.0 55 55 A G H X S+ 0 0 0 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.830 103.7 56.0 -50.4 -45.1 20.6 27.4 2.4 56 56 A V H X S+ 0 0 61 -4,-1.7 4,-1.7 1,-0.2 -1,-0.2 0.856 108.4 47.5 -61.2 -40.0 23.8 29.2 3.4 57 57 A A H X S+ 0 0 0 -4,-1.5 4,-2.1 -3,-0.3 -2,-0.2 0.900 112.4 47.7 -72.9 -38.3 23.7 31.3 0.4 58 58 A I H X S+ 0 0 1 -4,-2.1 4,-2.2 1,-0.2 5,-0.3 0.971 111.6 50.5 -63.7 -52.1 20.0 32.3 0.7 59 59 A Q H X S+ 0 0 90 -4,-2.6 4,-2.1 1,-0.2 -1,-0.2 0.905 110.8 49.1 -53.6 -40.9 20.3 33.1 4.3 60 60 A E H X S+ 0 0 49 -4,-1.7 4,-2.9 1,-0.2 -1,-0.2 0.934 110.1 49.3 -70.9 -41.5 23.3 35.4 3.8 61 61 A K H <>S+ 0 0 11 -4,-2.1 5,-2.4 2,-0.2 6,-1.0 0.808 110.5 51.3 -67.9 -25.6 21.7 37.3 0.9 62 62 A L H ><5S+ 0 0 56 -4,-2.2 3,-1.1 -5,-0.2 -1,-0.2 0.928 113.0 46.2 -68.5 -40.3 18.6 37.8 3.0 63 63 A R H 3<5S+ 0 0 190 -4,-2.1 -2,-0.2 -5,-0.3 -3,-0.2 0.900 107.4 55.7 -64.5 -41.2 20.8 39.1 5.8 64 64 A E T 3<5S- 0 0 96 -4,-2.9 -1,-0.3 -5,-0.1 -2,-0.2 0.542 113.1-124.0 -69.9 -8.8 22.8 41.3 3.3 65 65 A Q T < 5S+ 0 0 180 -3,-1.1 -3,-0.2 -4,-0.3 -2,-0.1 0.805 74.6 128.3 64.5 39.2 19.3 42.8 2.4 66 66 A V S > - 0 0 106 -2,-0.3 3,-1.5 -3,-0.1 4,-0.6 -0.794 30.0-117.2-101.9 148.4 13.4 39.3 0.7 69 69 A R G >4 S+ 0 0 25 -2,-0.3 3,-1.5 1,-0.3 -1,-0.1 0.858 113.8 60.3 -52.7 -38.9 12.2 35.7 1.2 70 70 A E G 34 S+ 0 0 129 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.682 100.1 56.1 -64.7 -23.7 8.8 36.6 -0.6 71 71 A E G <4 S+ 0 0 79 -3,-1.5 -1,-0.3 2,-0.0 2,-0.2 0.624 95.4 84.5 -80.1 -16.5 10.7 37.5 -3.7 72 72 A L << - 0 0 4 -3,-1.5 2,-0.5 -4,-0.6 -31,-0.2 -0.557 62.0-156.7 -96.1 146.6 12.4 34.0 -3.8 73 73 A F E -e 41 0B 7 -33,-3.4 -31,-1.7 -2,-0.2 2,-0.5 -0.883 17.7-172.0-125.9 97.3 10.9 30.9 -5.4 74 74 A I E -e 42 0B 0 -2,-0.5 31,-1.6 -33,-0.2 32,-1.6 -0.827 0.9-170.5-106.6 126.1 12.5 27.9 -3.8 75 75 A V E +ef 43 106B 0 -33,-2.5 -31,-2.1 -2,-0.5 2,-0.3 -0.908 9.8 166.0-112.7 135.7 11.8 24.4 -5.2 76 76 A S E - f 0 107B 0 30,-2.1 32,-2.0 -2,-0.4 2,-0.3 -0.864 20.9-133.2-141.2-176.5 12.7 21.0 -3.8 77 77 A K E - f 0 108B 0 -2,-0.3 -31,-1.0 30,-0.2 2,-0.5 -0.997 15.7-121.4-144.9 136.5 11.7 17.4 -4.4 78 78 A L E - f 0 109B 0 30,-2.8 32,-1.7 -2,-0.3 33,-0.4 -0.675 38.3-130.4 -73.6 117.8 10.7 14.3 -2.3 79 79 A W > - 0 0 10 -2,-0.5 3,-1.7 31,-0.1 36,-0.1 -0.288 20.3-107.3 -77.7 162.3 13.2 11.5 -3.1 80 80 A C G > S+ 0 0 0 1,-0.3 35,-2.6 2,-0.1 3,-0.8 0.703 113.0 64.8 -62.3 -28.7 12.0 8.0 -4.1 81 81 A T G 3 S+ 0 0 1 1,-0.2 37,-0.3 33,-0.2 -1,-0.3 0.360 100.2 54.9 -77.8 1.7 13.0 6.3 -0.8 82 82 A Y G < + 0 0 54 -3,-1.7 -1,-0.2 1,-0.1 9,-0.2 -0.010 64.9 114.1-124.2 27.7 10.4 8.5 1.1 83 83 A H < + 0 0 3 -3,-0.8 53,-0.2 32,-0.3 60,-0.1 0.717 47.1 106.9 -76.6 -20.6 7.1 7.8 -0.8 84 84 A E S >> S- 0 0 45 1,-0.1 3,-2.6 -3,-0.1 4,-0.9 -0.363 80.0-125.8 -55.9 136.4 5.6 6.0 2.2 85 85 A K H >> S+ 0 0 114 1,-0.3 3,-0.6 2,-0.2 4,-0.6 0.859 109.8 56.3 -58.1 -37.9 3.0 8.4 3.7 86 86 A G H 34 S+ 0 0 78 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.536 109.1 47.7 -66.2 -7.5 4.6 8.2 7.1 87 87 A L H <> S+ 0 0 67 -3,-2.6 4,-1.8 -5,-0.1 -1,-0.2 0.587 89.7 80.5-112.1 -14.6 8.0 9.4 5.7 88 88 A V H S+ 0 0 46 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.901 110.3 48.9 -59.1 -43.7 10.0 14.1 7.7 91 91 A A H X S+ 0 0 10 -4,-1.8 4,-1.5 2,-0.2 -1,-0.2 0.888 112.1 48.5 -67.0 -39.3 11.6 14.3 4.3 92 92 A C H X S+ 0 0 0 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.935 111.3 49.7 -63.2 -47.6 10.1 17.7 3.6 93 93 A Q H X S+ 0 0 93 -4,-3.3 4,-2.6 -5,-0.2 -2,-0.2 0.836 106.1 56.2 -65.6 -30.0 11.2 19.0 7.0 94 94 A K H X S+ 0 0 97 -4,-1.9 4,-2.7 -5,-0.2 -1,-0.2 0.922 109.8 46.5 -62.8 -43.6 14.8 17.8 6.5 95 95 A T H X S+ 0 0 0 -4,-1.5 4,-2.7 2,-0.2 -2,-0.2 0.921 112.8 49.4 -63.1 -42.2 14.9 19.8 3.3 96 96 A L H <>S+ 0 0 8 -4,-2.3 5,-2.2 2,-0.2 4,-0.4 0.888 112.5 47.9 -63.3 -42.5 13.4 22.9 5.1 97 97 A S H ><5S+ 0 0 84 -4,-2.6 3,-0.9 2,-0.2 -2,-0.2 0.916 113.8 46.6 -68.5 -44.5 16.0 22.5 7.9 98 98 A D H 3<5S+ 0 0 9 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.892 114.6 46.2 -63.2 -43.2 18.8 22.2 5.5 99 99 A L T 3<5S- 0 0 1 -4,-2.7 -1,-0.3 -5,-0.2 -2,-0.2 0.535 107.2-129.1 -75.7 -4.8 17.7 25.1 3.4 100 100 A K T < 5 + 0 0 80 -3,-0.9 2,-0.3 -4,-0.4 -3,-0.2 0.789 65.7 129.2 57.7 32.7 17.1 27.1 6.6 101 101 A L < - 0 0 22 -5,-2.2 -1,-0.2 -6,-0.2 -2,-0.1 -0.734 59.4-148.4-110.7 160.9 13.6 28.0 5.4 102 102 A D S S+ 0 0 122 -2,-0.3 2,-0.3 1,-0.2 -1,-0.1 0.568 84.9 17.4-106.9 -6.6 10.2 27.7 7.0 103 103 A Y - 0 0 47 -7,-0.1 2,-0.4 3,-0.0 50,-0.2 -0.987 64.0-137.4-149.7 161.6 8.4 27.0 3.7 104 104 A L B -k 153 0C 0 48,-1.6 50,-2.0 -2,-0.3 51,-0.3 -0.923 13.5-143.5-108.8 146.7 9.0 25.9 0.1 105 105 A D S S+ 0 0 7 -31,-1.6 2,-0.3 -2,-0.4 -30,-0.2 0.804 89.6 10.6 -75.9 -28.3 7.3 27.7 -2.8 106 106 A L E -f 75 0B 1 -32,-1.6 -30,-2.1 48,-0.1 2,-0.4 -0.963 61.8-170.3-153.7 132.3 7.0 24.3 -4.6 107 107 A Y E -fg 76 156B 2 48,-1.7 50,-2.0 -2,-0.3 2,-0.3 -0.997 16.5-163.9-127.8 126.3 7.6 20.7 -3.6 108 108 A L E -fg 77 157B 0 -32,-2.0 -30,-2.8 -2,-0.4 2,-0.8 -0.838 31.1-118.3-111.0 141.2 7.6 17.9 -6.2 109 109 A I E -fg 78 158B 1 48,-2.2 50,-1.1 -2,-0.3 -30,-0.1 -0.741 36.5-149.2 -67.7 112.8 7.3 14.2 -6.2 110 110 A H S S- 0 0 10 -32,-1.7 -1,-0.2 -2,-0.8 -31,-0.1 0.888 71.1 -1.5 -64.0 -43.3 10.8 13.8 -7.8 111 111 A W - 0 0 44 -33,-0.4 -1,-0.2 2,-0.1 49,-0.2 -0.981 69.1-122.6-139.6 151.8 10.0 10.6 -9.6 112 112 A P S S+ 0 0 2 0, 0.0 2,-0.5 0, 0.0 197,-0.1 0.720 86.7 92.1 -74.0 -10.9 6.8 8.5 -9.7 113 113 A T - 0 0 7 195,-0.1 2,-0.4 23,-0.0 -2,-0.1 -0.694 66.0-148.2 -87.1 122.9 8.7 5.4 -8.5 114 114 A G - 0 0 0 -2,-0.5 19,-2.2 21,-0.3 2,-0.3 -0.740 15.3-155.0 -86.0 137.6 8.9 4.6 -4.8 115 115 A F B -L 132 0D 4 -35,-2.6 -32,-0.3 -2,-0.4 18,-0.1 -0.812 35.2 -78.4-111.4 154.6 12.1 2.8 -3.7 116 116 A K - 0 0 97 15,-2.9 17,-0.2 -2,-0.3 -1,-0.1 -0.176 57.8-110.9 -50.6 126.2 12.6 0.6 -0.7 117 117 A P + 0 0 52 0, 0.0 2,-0.2 0, 0.0 -35,-0.1 -0.363 67.5 97.8 -65.9 148.2 13.0 2.8 2.4 118 118 A G S S- 0 0 38 -37,-0.3 -37,-0.1 1,-0.1 -3,-0.0 -0.891 85.2 -69.0 154.5 178.3 16.4 3.0 4.0 119 119 A K S S+ 0 0 188 -2,-0.2 2,-0.2 2,-0.0 -1,-0.1 0.871 103.7 86.8 -65.2 -35.5 19.6 5.0 4.2 120 120 A E - 0 0 135 1,-0.1 -2,-0.0 -3,-0.1 0, 0.0 -0.463 65.1-154.9 -74.4 133.4 20.6 4.2 0.6 121 121 A F S S+ 0 0 43 1,-0.3 -1,-0.1 -2,-0.2 -41,-0.1 0.806 92.0 31.9 -79.5 -32.4 19.2 6.4 -2.1 122 122 A F S S- 0 0 87 -42,-0.1 2,-0.3 -41,-0.0 -1,-0.3 -0.635 81.7-167.5-122.3 72.7 19.4 3.9 -4.9 123 123 A P - 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