==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=3-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 01-APR-07 2PDI . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.STEUBER,A.HEINE,G.KLEBE . 315 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13971.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 198 62.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 41 13.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 27.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 2 1 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 123 0, 0.0 13,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 131.1 14.0 11.7 39.9 2 2 A S + 0 0 71 11,-0.1 12,-2.5 12,-0.1 13,-0.4 0.617 360.0 47.8 -87.3 -17.1 12.7 8.3 38.7 3 3 A R E -A 13 0A 118 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.926 59.7-149.9-132.3 155.5 10.3 9.4 36.0 4 4 A I E -A 12 0A 36 8,-2.3 8,-2.6 -2,-0.3 2,-0.4 -0.921 28.1-115.0-117.9 140.2 10.2 11.6 32.9 5 5 A L E -A 11 0A 113 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.665 28.1-152.6 -81.3 129.9 7.1 13.3 31.5 6 6 A L > - 0 0 4 4,-3.0 3,-1.8 -2,-0.4 198,-0.1 -0.544 29.2-108.0 -91.7 162.7 5.9 12.3 28.1 7 7 A N T 3 S+ 0 0 67 196,-0.4 171,-0.2 173,-0.3 -2,-0.0 0.246 116.4 65.0 -76.3 9.3 3.9 14.4 25.7 8 8 A N T 3 S- 0 0 64 2,-0.3 -1,-0.3 172,-0.1 3,-0.1 0.254 119.8-107.9-104.2 1.3 0.8 12.3 26.3 9 9 A G S < S+ 0 0 55 -3,-1.8 2,-0.2 1,-0.3 -2,-0.1 0.400 82.1 116.6 88.8 -3.5 0.8 13.6 29.9 10 10 A A - 0 0 37 144,-0.1 -4,-3.0 95,-0.1 2,-0.4 -0.600 63.1-118.6 -94.4 161.3 1.9 10.4 31.5 11 11 A K E -A 5 0A 112 -6,-0.2 -6,-0.2 -2,-0.2 -8,-0.0 -0.825 22.3-159.0-102.2 137.8 5.1 9.7 33.5 12 12 A M E -A 4 0A 1 -8,-2.6 -8,-2.3 -2,-0.4 2,-0.1 -0.968 23.2-116.5-119.1 127.9 7.6 7.0 32.3 13 13 A P E -A 3 0A 14 0, 0.0 -10,-0.3 0, 0.0 -11,-0.1 -0.455 17.7-143.3 -61.0 129.4 10.3 5.4 34.6 14 14 A I S S+ 0 0 19 -12,-2.5 245,-2.9 244,-0.1 2,-0.5 0.645 86.6 58.0 -73.0 -14.3 13.8 6.3 33.3 15 15 A L B +b 259 0B 3 -13,-0.4 25,-0.5 243,-0.2 26,-0.3 -0.947 67.5 164.6-116.4 127.8 15.0 2.8 34.2 16 16 A G - 0 0 0 243,-2.4 2,-0.5 -2,-0.5 26,-0.2 -0.940 37.3-107.8-131.2 164.4 13.5 -0.3 32.7 17 17 A L E -c 42 0B 2 24,-2.3 26,-2.7 -2,-0.3 245,-0.3 -0.811 29.1-140.8 -89.5 121.0 14.3 -4.0 32.4 18 18 A G E -cd 43 262B 5 243,-2.1 245,-0.7 -2,-0.5 26,-0.1 -0.547 16.2-174.9 -75.5 148.6 15.3 -5.2 28.9 19 19 A T > + 0 0 0 24,-0.5 3,-1.6 -2,-0.2 2,-0.4 0.340 37.4 125.7-129.6 2.1 14.0 -8.7 27.8 20 20 A W T 3 S+ 0 0 69 1,-0.3 -2,-0.1 23,-0.1 242,-0.1 -0.564 89.5 5.5 -68.6 124.6 15.6 -9.3 24.4 21 21 A K T 3 S+ 0 0 49 -2,-0.4 -1,-0.3 1,-0.3 28,-0.0 0.375 88.8 143.1 82.4 1.8 17.4 -12.7 24.6 22 22 A S < - 0 0 4 -3,-1.6 -1,-0.3 1,-0.1 5,-0.1 -0.692 58.9-116.6 -71.1 115.6 16.0 -13.4 28.1 23 23 A P >> - 0 0 49 0, 0.0 3,-2.3 0, 0.0 4,-1.9 -0.237 15.4-124.9 -58.5 140.7 15.4 -17.2 28.0 24 24 A P H 3> S+ 0 0 69 0, 0.0 4,-0.5 0, 0.0 -2,-0.0 0.837 110.6 55.4 -58.7 -31.7 11.7 -18.0 28.4 25 25 A G H 34 S+ 0 0 81 1,-0.2 4,-0.1 2,-0.1 -3,-0.0 0.454 118.5 33.7 -77.1 -1.2 12.6 -20.4 31.4 26 26 A Q H <> S+ 0 0 101 -3,-2.3 4,-1.9 2,-0.1 -1,-0.2 0.579 97.6 76.6-123.1 -20.1 14.4 -17.5 33.2 27 27 A V H X S+ 0 0 0 -4,-1.9 4,-2.5 1,-0.2 5,-0.2 0.781 88.2 61.3 -75.7 -24.0 12.6 -14.3 32.4 28 28 A T H X S+ 0 0 29 -4,-0.5 4,-2.1 1,-0.2 -1,-0.2 0.985 111.3 39.2 -63.1 -49.2 9.6 -14.9 34.7 29 29 A E H > S+ 0 0 106 1,-0.2 4,-2.7 2,-0.2 5,-0.3 0.871 113.1 57.0 -66.2 -35.0 11.9 -15.0 37.7 30 30 A A H X S+ 0 0 1 -4,-1.9 4,-2.3 1,-0.2 -1,-0.2 0.937 109.5 44.0 -60.9 -44.5 14.0 -12.1 36.3 31 31 A V H X S+ 0 0 0 -4,-2.5 4,-2.4 1,-0.2 5,-0.2 0.867 112.3 53.4 -71.5 -35.2 10.9 -9.8 36.0 32 32 A K H X S+ 0 0 53 -4,-2.1 4,-2.1 -5,-0.2 -1,-0.2 0.911 111.5 44.6 -63.2 -46.7 9.7 -10.9 39.5 33 33 A V H X S+ 0 0 20 -4,-2.7 4,-1.9 2,-0.2 -2,-0.2 0.906 111.6 55.3 -62.2 -40.0 13.1 -10.0 41.1 34 34 A A H X>S+ 0 0 0 -4,-2.3 5,-2.2 -5,-0.3 4,-0.8 0.960 109.7 43.9 -62.1 -48.1 13.2 -6.8 39.1 35 35 A I H ><5S+ 0 0 1 -4,-2.4 3,-1.0 1,-0.2 -1,-0.2 0.950 110.9 56.5 -62.9 -39.5 9.8 -5.6 40.5 36 36 A D H 3<5S+ 0 0 91 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.860 110.5 43.7 -58.7 -35.9 10.8 -6.7 44.0 37 37 A V H 3<5S- 0 0 63 -4,-1.9 -1,-0.2 -3,-0.3 -2,-0.2 0.404 133.1 -80.5-100.5 6.3 13.9 -4.5 43.9 38 38 A G T <<5S+ 0 0 20 -3,-1.0 -3,-0.2 -4,-0.8 -2,-0.1 0.218 76.9 139.9 129.2 -12.9 12.2 -1.5 42.4 39 39 A Y < + 0 0 0 -5,-2.2 -1,-0.3 -6,-0.2 -23,-0.1 -0.342 14.4 170.6 -63.5 139.1 11.8 -1.7 38.6 40 40 A R + 0 0 71 -25,-0.5 33,-2.9 1,-0.1 2,-0.4 0.288 59.0 68.0-127.6 6.3 8.5 -0.4 37.4 41 41 A H E - e 0 73B 0 -26,-0.3 -24,-2.3 31,-0.2 2,-0.4 -0.997 56.0-173.6-130.4 128.6 9.2 -0.4 33.6 42 42 A I E -ce 17 74B 0 31,-1.5 33,-2.4 -2,-0.4 2,-0.6 -0.990 14.6-147.5-121.9 130.8 9.6 -3.5 31.5 43 43 A D E +ce 18 75B 4 -26,-2.7 -24,-0.5 -2,-0.4 2,-0.2 -0.898 31.4 165.7 -99.9 121.2 10.6 -3.3 27.8 44 44 A C - 0 0 0 31,-2.3 2,-0.3 -2,-0.6 3,-0.1 -0.717 19.2-170.4-125.3 173.1 9.1 -6.2 25.7 45 45 A A > > - 0 0 0 -2,-0.2 3,-1.8 31,-0.2 5,-0.5 -0.891 31.9-129.2-168.1 144.8 8.4 -7.3 22.1 46 46 A H G > 5S+ 0 0 39 31,-1.0 3,-1.7 1,-0.3 5,-0.2 0.875 110.6 59.6 -59.5 -36.5 6.5 -9.9 20.3 47 47 A V G 3 5S+ 0 0 25 1,-0.3 -1,-0.3 30,-0.3 74,-0.1 0.633 90.0 69.3 -71.8 -8.2 9.6 -10.8 18.3 48 48 A Y G < 5S- 0 0 40 -3,-1.8 -1,-0.3 -28,-0.0 -27,-0.2 0.657 95.2-143.7 -80.5 -17.0 11.5 -11.6 21.5 49 49 A Q T < 5S+ 0 0 143 -3,-1.7 -3,-0.1 -4,-0.4 -2,-0.1 0.715 77.7 88.0 65.8 27.1 9.2 -14.7 21.8 50 50 A N >< + 0 0 2 -5,-0.5 4,-2.3 2,-0.1 5,-0.2 0.263 41.2 112.1-137.6 13.8 8.9 -14.4 25.6 51 51 A E H > S+ 0 0 3 -6,-0.2 4,-2.6 1,-0.2 5,-0.2 0.852 77.1 58.0 -64.2 -33.0 6.0 -12.1 26.3 52 52 A N H > S+ 0 0 79 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.953 109.7 43.6 -60.4 -45.5 3.9 -14.9 27.8 53 53 A E H > S+ 0 0 56 2,-0.2 4,-1.3 1,-0.2 -2,-0.2 0.862 113.0 51.6 -67.6 -36.8 6.6 -15.6 30.4 54 54 A V H X S+ 0 0 0 -4,-2.3 4,-2.1 1,-0.2 3,-0.3 0.926 109.3 52.4 -60.2 -43.3 7.1 -11.9 31.1 55 55 A G H X S+ 0 0 0 -4,-2.6 4,-2.9 43,-0.2 5,-0.2 0.858 100.8 59.7 -62.8 -36.7 3.4 -11.6 31.6 56 56 A V H X S+ 0 0 64 -4,-1.7 4,-2.1 1,-0.2 -1,-0.2 0.904 108.3 45.8 -57.3 -43.0 3.3 -14.5 34.1 57 57 A A H X S+ 0 0 0 -4,-1.3 4,-2.3 -3,-0.3 -2,-0.2 0.927 113.0 48.8 -68.4 -46.7 5.7 -12.5 36.3 58 58 A I H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 5,-0.2 0.945 113.3 47.9 -57.1 -48.2 3.7 -9.2 35.9 59 59 A Q H X S+ 0 0 93 -4,-2.9 4,-2.8 1,-0.2 -1,-0.2 0.866 110.4 51.6 -62.9 -41.0 0.4 -11.0 36.7 60 60 A E H X S+ 0 0 46 -4,-2.1 4,-2.8 -5,-0.2 -1,-0.2 0.899 111.0 46.5 -66.7 -40.7 1.9 -12.7 39.7 61 61 A K H <>S+ 0 0 14 -4,-2.3 5,-2.3 1,-0.2 6,-0.9 0.872 113.9 48.6 -76.0 -29.5 3.2 -9.4 41.2 62 62 A L H ><5S+ 0 0 33 -4,-2.3 3,-1.5 -5,-0.2 -2,-0.2 0.937 113.3 47.1 -63.8 -49.1 -0.1 -7.7 40.6 63 63 A R H 3<5S+ 0 0 154 -4,-2.8 -2,-0.2 1,-0.3 -3,-0.2 0.931 111.3 50.6 -61.9 -40.8 -2.0 -10.6 42.1 64 64 A E T 3<5S- 0 0 90 -4,-2.8 -1,-0.3 -5,-0.2 -2,-0.2 0.555 111.7-126.2 -67.5 -14.2 0.4 -10.6 45.1 65 65 A Q T < 5 + 0 0 171 -3,-1.5 -3,-0.2 -4,-0.3 3,-0.1 0.813 69.1 135.1 62.0 36.8 -0.3 -6.8 45.4 66 66 A V S > - 0 0 99 -2,-0.3 3,-1.3 -3,-0.1 4,-0.6 -0.713 29.9-117.0 -89.5 148.3 -0.6 -1.7 41.3 69 69 A R G >4 S+ 0 0 34 -2,-0.3 3,-1.5 1,-0.2 -1,-0.1 0.863 115.6 59.5 -54.1 -37.7 -1.1 -1.7 37.6 70 70 A E G 34 S+ 0 0 132 1,-0.3 -1,-0.2 3,-0.1 0, 0.0 0.739 101.3 56.4 -62.6 -25.5 -1.1 2.1 37.5 71 71 A E G <4 S+ 0 0 81 -3,-1.3 2,-0.3 2,-0.0 -1,-0.3 0.572 95.4 82.2 -82.8 -11.7 2.4 1.9 39.0 72 72 A L << - 0 0 3 -3,-1.5 2,-0.5 -4,-0.6 -31,-0.2 -0.722 60.5-159.3 -96.3 150.1 3.8 -0.2 36.1 73 73 A F E -e 41 0B 8 -33,-2.9 -31,-1.5 -2,-0.3 2,-0.5 -0.934 16.7-173.7-126.9 98.7 5.0 1.1 32.8 74 74 A I E -e 42 0B 0 -2,-0.5 31,-1.6 -33,-0.2 32,-1.4 -0.876 1.0-169.1-107.7 126.4 4.9 -1.8 30.3 75 75 A V E +ef 43 106B 1 -33,-2.4 -31,-2.3 -2,-0.5 2,-0.3 -0.903 10.7 165.9-113.9 138.2 6.2 -1.3 26.8 76 76 A S E - f 0 107B 0 30,-1.8 32,-2.1 -2,-0.4 2,-0.3 -0.828 21.1-134.5-143.5 177.5 5.9 -3.5 23.7 77 77 A K E - f 0 108B 0 -2,-0.3 -31,-1.0 30,-0.2 2,-0.5 -0.997 15.8-119.1-143.8 139.6 6.5 -3.1 20.0 78 78 A L E - f 0 109B 0 30,-2.9 32,-1.8 -2,-0.3 33,-0.4 -0.704 38.7-129.4 -75.1 117.3 4.8 -3.9 16.7 79 79 A W > - 0 0 10 -2,-0.5 3,-1.9 31,-0.1 36,-0.1 -0.252 21.2-105.9 -75.1 156.5 7.0 -6.3 14.6 80 80 A C G > S+ 0 0 0 1,-0.3 35,-2.6 2,-0.2 3,-0.9 0.725 114.2 62.3 -50.4 -30.2 7.9 -5.6 11.0 81 81 A T G 3 S+ 0 0 1 1,-0.2 -1,-0.3 33,-0.2 37,-0.3 0.354 100.0 56.5 -84.2 9.7 5.6 -8.2 9.5 82 82 A Y G < + 0 0 52 -3,-1.9 -1,-0.2 35,-0.1 -2,-0.2 0.046 64.0 114.2-127.2 24.7 2.5 -6.5 10.9 83 83 A H < + 0 0 3 -3,-0.9 60,-0.1 32,-0.3 53,-0.1 0.673 50.8 106.8 -70.6 -19.1 2.7 -2.9 9.5 84 84 A E S >> S- 0 0 42 1,-0.1 3,-2.3 -3,-0.1 4,-1.1 -0.326 80.5-120.2 -63.8 138.8 -0.5 -3.4 7.4 85 85 A K H >> S+ 0 0 170 1,-0.3 3,-0.5 2,-0.2 4,-0.5 0.832 110.6 51.2 -42.5 -47.2 -3.6 -1.6 8.6 86 86 A G H 34 S+ 0 0 63 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.453 111.1 48.1 -78.8 -2.6 -5.6 -4.8 9.1 87 87 A L H <> S+ 0 0 66 -3,-2.3 4,-2.0 -5,-0.1 -1,-0.2 0.630 87.6 80.7-112.5 -14.1 -2.9 -6.5 11.2 88 88 A V H S+ 0 0 43 -4,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.878 110.7 51.8 -63.1 -39.9 -4.5 -8.2 16.3 91 91 A A H X S+ 0 0 13 -4,-2.0 4,-2.2 1,-0.2 -1,-0.2 0.940 112.3 45.3 -61.1 -48.5 -0.7 -7.8 16.8 92 92 A C H X S+ 0 0 0 -4,-2.3 4,-2.6 -5,-0.2 -2,-0.2 0.931 112.8 51.0 -61.2 -45.1 -1.3 -5.5 19.7 93 93 A Q H X S+ 0 0 93 -4,-2.6 4,-2.4 2,-0.2 5,-0.2 0.844 107.4 52.8 -64.5 -33.6 -4.0 -7.7 21.2 94 94 A K H X S+ 0 0 103 -4,-2.2 4,-2.6 2,-0.2 -1,-0.2 0.955 111.1 47.5 -64.6 -47.3 -1.8 -10.8 21.0 95 95 A T H X S+ 0 0 0 -4,-2.2 4,-2.6 1,-0.2 -2,-0.2 0.921 111.9 50.5 -56.7 -46.5 0.9 -8.9 22.9 96 96 A L H X>S+ 0 0 9 -4,-2.6 5,-2.5 2,-0.2 4,-0.6 0.911 111.7 46.6 -59.7 -45.8 -1.7 -7.8 25.4 97 97 A S H ><5S+ 0 0 82 -4,-2.4 3,-0.6 2,-0.2 -1,-0.2 0.900 113.6 48.5 -63.6 -43.8 -3.0 -11.3 26.0 98 98 A D H 3<5S+ 0 0 19 -4,-2.6 -43,-0.2 1,-0.2 -2,-0.2 0.909 113.1 46.5 -65.9 -39.4 0.4 -12.7 26.3 99 99 A L H 3<5S- 0 0 0 -4,-2.6 -1,-0.2 -5,-0.2 -2,-0.2 0.499 109.5-123.6 -79.4 -6.4 1.5 -10.0 28.8 100 100 A K T <<5 + 0 0 60 -3,-0.6 2,-0.3 -4,-0.6 -3,-0.2 0.825 67.5 134.2 67.7 32.9 -1.8 -10.5 30.8 101 101 A L < - 0 0 11 -5,-2.5 -1,-0.3 -6,-0.2 3,-0.1 -0.812 57.3-154.4-112.4 154.0 -2.6 -6.8 30.3 102 102 A D S S+ 0 0 144 1,-0.3 2,-0.3 -2,-0.3 -1,-0.1 0.573 88.3 10.4 -97.2 -16.8 -5.7 -4.9 29.3 103 103 A Y - 0 0 46 -7,-0.1 2,-0.3 3,-0.0 -1,-0.3 -0.973 69.0-130.3-147.9 158.3 -3.6 -2.0 28.0 104 104 A L B -k 153 0C 0 48,-1.9 50,-2.4 -2,-0.3 51,-0.3 -0.832 11.6-142.8 -98.1 150.6 0.0 -1.1 27.3 105 105 A D S S+ 0 0 19 -31,-1.6 2,-0.3 -2,-0.3 -30,-0.2 0.851 89.9 8.6 -77.1 -31.4 1.6 2.1 28.6 106 106 A L E -f 75 0B 0 -32,-1.4 -30,-1.8 48,-0.2 2,-0.4 -0.965 62.7-170.4-151.5 130.0 3.6 2.5 25.4 107 107 A Y E -fg 76 156B 1 48,-1.6 50,-1.8 -2,-0.3 2,-0.3 -1.000 17.2-162.4-125.3 129.5 3.5 0.6 22.0 108 108 A L E -fg 77 157B 0 -32,-2.1 -30,-2.9 -2,-0.4 2,-0.8 -0.808 30.1-118.4-113.1 145.4 6.2 1.3 19.5 109 109 A I E -fg 78 158B 1 48,-2.1 50,-1.2 -2,-0.3 -30,-0.1 -0.790 36.4-148.8 -72.2 115.5 6.7 0.8 15.8 110 110 A H S S- 0 0 10 -32,-1.8 -1,-0.2 -2,-0.8 -31,-0.1 0.865 70.7 -1.5 -65.8 -43.7 9.7 -1.6 16.3 111 111 A W - 0 0 42 -33,-0.4 -1,-0.2 2,-0.2 49,-0.2 -0.953 69.9-119.9-142.4 151.4 11.5 -0.6 13.1 112 112 A P S S+ 0 0 1 0, 0.0 2,-0.4 0, 0.0 197,-0.1 0.689 88.6 90.0 -69.5 -15.2 10.5 1.8 10.3 113 113 A T - 0 0 5 195,-0.1 2,-0.3 23,-0.1 -2,-0.2 -0.670 65.0-149.7 -87.2 123.8 10.6 -1.1 7.8 114 114 A G - 0 0 1 -2,-0.4 19,-1.7 21,-0.4 2,-0.3 -0.743 14.8-159.6 -88.4 142.8 7.5 -3.2 7.0 115 115 A F B -L 132 0D 2 -35,-2.6 -32,-0.3 -2,-0.3 18,-0.1 -0.866 35.6 -77.6-119.2 156.0 8.1 -6.8 5.9 116 116 A K - 0 0 100 15,-2.6 17,-0.1 -2,-0.3 15,-0.1 -0.172 56.9-114.4 -49.5 125.9 6.0 -9.2 4.0 117 117 A P + 0 0 46 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.318 65.1 90.5 -67.4 153.0 3.3 -10.6 6.4 118 118 A G S S- 0 0 42 -37,-0.3 -37,-0.1 1,-0.1 0, 0.0 -0.936 89.2 -55.8 153.6-168.2 3.3 -14.3 7.3 119 119 A K S S+ 0 0 207 -2,-0.3 2,-0.3 3,-0.0 -1,-0.1 0.842 107.0 85.7 -68.6 -35.0 4.6 -16.8 9.9 120 120 A E - 0 0 128 1,-0.1 -2,-0.1 -3,-0.1 0, 0.0 -0.503 63.2-157.8 -76.8 129.2 8.3 -15.8 9.3 121 121 A F S S+ 0 0 41 1,-0.3 -1,-0.1 -2,-0.3 -41,-0.1 0.763 96.2 33.3 -77.7 -30.6 9.6 -12.7 11.3 122 122 A F S S- 0 0 87 -42,-0.1 -1,-0.3 -41,-0.0 2,-0.3 -0.718 82.4-165.8-128.2 78.3 12.3 -12.2 8.6 123 123 A P - 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