==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=3-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE(SERINE PROTEASE) 08-DEC-91 2PF2 . COMPND 2 MOLECULE: PROTHROMBIN FRAGMENT 1; . SOURCE 2 ORGANISM_SCIENTIFIC: BOS TAURUS; . AUTHOR M.SORIANO-GARCIA,K.PADMANABHAN,A.M.DE VOS,A.TULINSKY . 145 1 5 5 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8370.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 62 42.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 1.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 6.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 6 4.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 12 8.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 25 17.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 16 0, 0.0 16,-0.1 0, 0.0 22,-0.0 0.000 360.0 360.0 360.0 -12.0 2.0 32.7 126.4 2 2 A N + 0 0 49 1,-0.0 4,-0.0 25,-0.0 21,-0.0 0.973 360.0 127.5 72.3 72.0 -1.1 33.3 128.5 3 3 A K + 0 0 172 2,-0.0 -1,-0.0 0, 0.0 0, 0.0 0.141 43.7 57.2-152.8 35.4 -1.3 30.0 130.3 4 4 A G S S- 0 0 61 0, 0.0 2,-0.2 0, 0.0 0, 0.0 0.394 93.0 -65.0-125.8 -99.7 -1.6 30.1 134.1 5 5 A F S S- 0 0 175 0, 0.0 -2,-0.0 0, 0.0 -3,-0.0 -0.621 111.7 -13.8-172.9 95.2 -3.9 31.6 136.6 6 6 A L S > S+ 0 0 111 -2,-0.2 3,-0.8 2,-0.0 -4,-0.0 0.765 79.0 144.1 71.9 38.3 -3.9 35.3 136.5 7 7 A X G > + 0 0 42 1,-0.2 3,-1.5 2,-0.1 -1,-0.0 0.906 68.9 60.3 -72.7 -37.2 -0.7 36.0 134.4 8 8 A X G 3 S+ 0 0 106 1,-0.3 -1,-0.2 4,-0.0 4,-0.1 0.323 87.7 72.0 -71.8 6.4 -2.2 39.1 132.7 9 9 A V G < S+ 0 0 124 -3,-0.8 -1,-0.3 2,-0.1 2,-0.3 0.241 95.4 76.9 -99.6 -3.3 -2.7 40.9 136.1 10 10 A R S < S- 0 0 156 -3,-1.5 2,-0.3 3,-0.0 3,-0.0 -0.758 98.5 -83.6-114.9 165.6 1.1 41.2 136.0 11 11 A K - 0 0 189 -2,-0.3 20,-0.1 1,-0.0 -2,-0.1 -0.546 50.3-119.9 -68.9 125.1 3.6 43.3 134.2 12 12 A G - 0 0 14 18,-0.3 2,-0.3 -2,-0.3 16,-0.1 -0.295 34.3-166.3 -61.8 155.9 4.3 41.8 130.8 13 13 A N > - 0 0 72 14,-0.1 4,-1.9 1,-0.1 5,-0.3 -0.923 24.2-137.9-149.3 143.5 8.0 40.8 130.4 14 14 A L H >>S+ 0 0 36 17,-0.4 4,-2.1 -2,-0.3 5,-1.4 0.817 100.0 43.2 -76.3 -44.4 10.0 39.8 127.4 15 15 A X H >>S+ 0 0 113 3,-0.2 5,-1.2 2,-0.2 4,-0.7 0.971 121.5 40.4 -57.7 -56.9 12.1 36.8 128.7 16 16 A R H >5S+ 0 0 33 1,-0.2 4,-0.5 3,-0.2 -2,-0.2 0.990 125.1 33.4 -54.6 -65.0 9.1 35.2 130.5 17 17 A X H <5S+ 0 0 1 -4,-1.9 -3,-0.2 1,-0.2 -1,-0.2 0.765 135.1 10.3 -70.8 -33.8 6.5 35.9 127.9 18 18 A a H <5S+ 0 0 4 -4,-2.1 5,-0.2 -5,-0.3 -3,-0.2 0.652 127.5 43.6-121.8 -29.5 8.2 35.6 124.5 19 19 A L H < - 0 0 46 -2,-0.3 4,-1.1 1,-0.1 5,-0.1 -0.297 41.3-108.2 -85.0 166.3 1.2 36.9 120.5 25 25 A R H > S+ 0 0 92 1,-0.2 4,-2.4 2,-0.2 17,-0.1 0.785 122.2 58.4 -67.4 -29.8 2.1 40.3 119.1 26 26 A X H > S+ 0 0 129 1,-0.2 4,-2.9 2,-0.2 -1,-0.2 0.779 102.8 51.0 -71.4 -30.8 0.0 41.8 121.9 27 27 A X H > S+ 0 0 10 2,-0.2 4,-0.8 3,-0.2 -1,-0.2 0.804 113.2 45.1 -71.9 -35.9 2.1 40.1 124.5 28 28 A A H < S+ 0 0 0 -4,-1.1 3,-0.4 2,-0.2 4,-0.3 0.925 115.2 47.8 -75.1 -42.8 5.3 41.5 123.0 29 29 A F H >X S+ 0 0 64 -4,-2.4 4,-2.5 1,-0.3 3,-2.4 0.917 108.8 53.7 -55.5 -61.3 3.8 44.9 122.6 30 30 A X H 3< S+ 0 0 108 -4,-2.9 -18,-0.3 1,-0.3 -1,-0.3 0.681 112.4 45.9 -50.1 -26.7 2.5 44.7 126.2 31 31 A A T 3< S+ 0 0 26 -4,-0.8 -17,-0.4 -3,-0.4 -1,-0.3 0.407 118.9 40.0 -98.1 1.5 6.1 44.0 127.3 32 32 A L T <4 S- 0 0 45 -3,-2.4 2,-0.9 -4,-0.3 -2,-0.2 0.722 72.3-160.7-120.2 -43.6 7.8 46.7 125.1 33 33 A X < + 0 0 203 -4,-2.5 -1,-0.2 -5,-0.1 5,-0.1 -0.870 67.1 86.5 90.1-105.6 5.8 49.9 125.1 34 34 A S - 0 0 54 -2,-0.9 4,-0.5 1,-0.2 -2,-0.1 0.221 66.1-153.9 -31.1 126.6 7.2 51.5 122.0 35 35 A L S > S+ 0 0 94 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.674 97.0 63.6 -72.9 -30.7 5.3 50.2 119.1 36 36 A S H > S+ 0 0 81 2,-0.2 4,-1.3 1,-0.2 -1,-0.2 0.768 101.6 44.5 -64.0 -37.9 8.5 50.9 117.3 37 37 A A H > S+ 0 0 39 2,-0.2 4,-2.2 3,-0.1 -1,-0.2 0.663 113.0 55.0 -81.5 -16.9 10.6 48.4 119.2 38 38 A T H > S+ 0 0 0 -4,-0.5 4,-3.2 2,-0.2 -2,-0.2 0.806 107.7 47.2 -81.7 -44.4 7.6 45.9 118.8 39 39 A D H X S+ 0 0 34 -4,-2.6 4,-0.9 2,-0.2 -2,-0.2 0.909 116.7 45.3 -61.9 -53.9 7.7 46.3 115.0 40 40 A A H X S+ 0 0 44 -4,-1.3 4,-1.7 2,-0.2 -2,-0.2 0.895 121.5 38.8 -54.6 -50.4 11.5 45.8 115.3 41 41 A F H X S+ 0 0 24 -4,-2.2 4,-1.9 2,-0.2 3,-0.4 0.987 111.4 53.8 -62.3 -73.5 11.1 42.8 117.6 42 42 A W H X S+ 0 0 64 -4,-3.2 4,-1.8 1,-0.2 -1,-0.2 0.707 111.8 50.0 -38.1 -33.1 8.1 41.2 116.0 43 43 A A H X S+ 0 0 23 -4,-0.9 4,-1.1 -5,-0.2 -1,-0.2 0.900 113.7 40.8 -73.1 -52.9 10.1 41.2 112.8 44 44 A K H < S+ 0 0 54 -4,-1.7 -2,-0.2 -3,-0.4 -3,-0.1 0.561 118.8 52.0 -81.0 0.5 13.2 39.7 114.1 45 45 A Y H >< S+ 0 0 6 -4,-1.9 3,-1.2 2,-0.1 -2,-0.2 0.876 107.0 46.0 -96.4 -52.2 11.0 37.3 116.1 46 46 A T H >< S+ 0 0 62 -4,-1.8 3,-0.6 -5,-0.3 -2,-0.2 0.693 110.3 57.8 -60.4 -27.6 8.7 35.9 113.5 47 47 A A T 3< S+ 0 0 22 -4,-1.1 26,-0.3 1,-0.2 25,-0.3 0.567 105.4 51.2 -80.8 -8.0 11.9 35.4 111.3 48 48 A b T X S+ 0 0 0 -3,-1.2 3,-2.1 1,-0.1 -1,-0.2 0.194 72.9 111.9-114.2 10.6 13.4 33.2 114.0 49 49 A E T < S+ 0 0 139 -3,-0.6 3,-0.4 1,-0.3 -1,-0.1 0.668 77.7 51.9 -57.1 -29.7 10.4 30.9 114.5 50 50 A S T 3 S+ 0 0 81 -3,-0.2 -1,-0.3 1,-0.2 -2,-0.1 -0.017 108.3 53.6 -94.9 18.1 12.3 28.0 113.0 51 51 A A < + 0 0 0 -3,-2.1 10,-0.2 17,-0.1 -1,-0.2 0.011 66.2 118.4-139.7 21.6 15.2 28.6 115.5 52 52 A R + 0 0 48 -3,-0.4 6,-0.3 1,-0.2 5,-0.2 0.925 60.3 82.7 -58.5 -44.0 13.4 28.6 118.8 53 53 A N S S+ 0 0 132 4,-0.1 2,-0.2 2,-0.1 -1,-0.2 -0.953 82.5 30.7-128.3 137.2 15.3 25.6 120.1 54 54 A P S S- 0 0 79 0, 0.0 4,-0.1 0, 0.0 0, 0.0 0.596 84.2-140.0 -59.6 177.9 17.9 25.3 121.4 55 55 A R S > S+ 0 0 73 2,-0.3 4,-2.3 -2,-0.2 -2,-0.1 0.526 102.5 60.0 -90.7 -6.5 17.6 28.7 122.9 56 56 A E H > S+ 0 0 137 2,-0.2 4,-0.6 1,-0.2 -1,-0.2 0.527 106.2 51.5 -88.2 -19.0 21.3 29.5 122.2 57 57 A K H > S+ 0 0 75 2,-0.2 4,-1.3 -5,-0.2 -2,-0.3 0.652 109.4 48.9 -86.4 -26.2 20.2 28.9 118.7 58 58 A L H > S+ 0 0 4 -6,-0.3 4,-2.3 2,-0.2 5,-0.3 0.938 108.8 51.0 -80.4 -45.5 17.4 31.4 119.4 59 59 A N H X S+ 0 0 73 -4,-2.3 4,-1.3 1,-0.2 -2,-0.2 0.817 110.2 53.9 -61.3 -23.4 19.8 33.9 120.8 60 60 A E H <>S+ 0 0 61 -4,-0.6 5,-0.5 1,-0.2 6,-0.4 0.930 110.9 40.5 -74.4 -48.1 21.9 33.4 117.6 61 61 A b H <5S+ 0 0 0 -4,-1.3 3,-0.4 -3,-0.3 -2,-0.2 0.758 112.6 54.9 -70.0 -31.4 19.1 34.1 115.1 62 62 A L H <5S+ 0 0 23 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.850 100.7 62.1 -74.3 -33.2 17.6 37.1 117.1 63 63 A E T <5S- 0 0 135 -4,-1.3 -1,-0.2 -5,-0.3 -2,-0.2 0.647 95.5-145.9 -62.8 -21.8 21.1 38.7 117.1 64 64 A G T 5 + 0 0 0 -3,-0.4 11,-2.7 -4,-0.4 12,-0.4 0.557 63.5 118.1 66.7 11.1 21.1 39.0 113.4 65 65 A N S > - 0 0 32 -2,-0.4 3,-1.3 75,-0.2 4,-0.6 -0.985 63.5 -27.1-122.4 118.5 19.0 31.9 109.3 69 69 A G T 34 S- 0 0 61 -2,-0.5 75,-0.1 1,-0.3 -2,-0.1 -0.701 142.1 -10.8 77.2-128.3 16.9 30.2 106.6 70 70 A V T 34 S- 0 0 55 -2,-0.4 -1,-0.3 54,-0.1 51,-0.1 0.643 105.5-106.8 -80.3 -8.0 16.5 32.8 103.8 71 71 A G T <4 S+ 0 0 0 -3,-1.3 -2,-0.1 53,-0.2 49,-0.1 0.907 71.9 142.2 78.0 55.5 18.0 35.5 106.1 72 72 A M S < S+ 0 0 87 -4,-0.6 -25,-0.1 -25,-0.3 -24,-0.1 0.532 77.8 55.1 -93.2 -13.9 15.0 37.6 107.1 73 73 A N S S+ 0 0 0 -5,-0.3 -1,-0.1 -26,-0.3 -7,-0.1 0.505 79.7 119.3 -93.8 -15.7 16.6 37.8 110.5 74 74 A Y + 0 0 8 42,-0.3 -9,-0.2 1,-0.1 -7,-0.1 -0.377 26.1 162.3 -61.8 130.9 19.8 39.1 109.2 75 75 A R + 0 0 24 -11,-2.7 -10,-0.2 -2,-0.1 -1,-0.1 -0.059 30.3 134.7-139.1 24.8 20.6 42.5 110.7 76 76 A G - 0 0 5 -12,-0.4 2,-0.3 39,-0.1 -11,-0.1 -0.250 64.3-114.0 -82.8 169.6 24.3 42.7 109.9 77 77 A N + 0 0 107 37,-0.1 2,-0.5 -2,-0.1 -1,-0.1 -0.202 67.8 126.8 -97.9 36.7 26.4 45.5 108.4 78 78 A V + 0 0 52 -2,-0.3 37,-3.3 37,-0.2 -2,-0.1 -0.894 24.3 166.7 -98.7 130.3 27.4 43.8 105.1 79 79 A S + 0 0 23 -2,-0.5 8,-1.0 35,-0.3 2,-0.4 0.489 40.9 91.7-127.6 -1.2 26.5 46.1 102.2 80 80 A V B -B 86 0B 46 6,-0.2 60,-0.5 1,-0.1 6,-0.2 -0.850 68.0-124.2-105.3 138.3 28.2 44.7 99.2 81 81 A T B -C 139 0C 5 4,-1.8 58,-0.2 -2,-0.4 59,-0.2 0.395 30.5 -91.3 -62.7-175.2 26.6 42.3 96.8 82 82 A R S S+ 0 0 116 56,-1.9 57,-0.1 1,-0.2 -2,-0.0 0.883 128.3 47.1 -68.2 -40.5 27.3 38.8 95.5 83 83 A S S S- 0 0 76 55,-0.3 -1,-0.2 2,-0.1 3,-0.1 0.541 119.7-107.2 -81.3 -17.5 29.1 40.5 92.5 84 84 A G S S+ 0 0 48 1,-0.3 2,-0.4 0, 0.0 -2,-0.1 0.108 74.4 139.5 105.3 -15.2 31.1 43.0 94.6 85 85 A I - 0 0 43 -5,-0.1 -4,-1.8 1,-0.1 -1,-0.3 -0.532 56.0-117.3 -58.6 123.6 28.9 45.9 93.6 86 86 A E B -B 80 0B 91 -2,-0.4 44,-1.6 -6,-0.2 45,-0.3 -0.045 31.2-108.2 -57.9 156.4 28.2 48.3 96.6 87 87 A d B -D 129 0D 4 -8,-1.0 42,-0.3 26,-0.3 2,-0.2 -0.653 23.7-118.1 -95.3 145.0 24.6 48.8 97.7 88 88 A Q - 0 0 3 40,-3.0 40,-0.4 -2,-0.3 42,-0.1 -0.494 43.1 -93.3 -70.1 139.1 22.4 52.0 97.2 89 89 A L - 0 0 61 5,-0.2 3,-0.4 1,-0.2 24,-0.2 -0.451 31.9-133.2 -54.7 137.0 21.2 53.7 100.4 90 90 A W S S+ 0 0 6 22,-1.9 -1,-0.2 1,-0.2 23,-0.1 0.644 109.2 47.2 -65.0 -28.8 17.7 52.3 101.1 91 91 A R S S+ 0 0 195 21,-0.3 -1,-0.2 10,-0.1 -2,-0.1 0.545 94.3 94.7 -87.6 -14.3 16.5 55.8 101.6 92 92 A S - 0 0 31 -3,-0.4 -4,-0.0 1,-0.1 0, 0.0 -0.240 63.0-156.0 -69.6 163.5 18.2 57.0 98.5 93 93 A R + 0 0 147 1,-0.2 -1,-0.1 4,-0.1 -3,-0.1 0.378 56.5 110.8-123.0 5.8 16.0 57.1 95.4 94 94 A Y S S+ 0 0 169 1,-0.1 -5,-0.2 -5,-0.1 -1,-0.2 -0.967 74.9 9.3-141.6 140.4 18.9 56.9 93.0 95 95 A P S S+ 0 0 57 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.978 140.1 15.9 -70.5 -16.3 20.1 54.9 91.0 96 96 A H S S- 0 0 19 33,-0.1 32,-0.1 39,-0.1 38,-0.0 -0.975 74.3-126.7-122.1 140.4 16.9 52.8 91.6 97 97 A K - 0 0 115 -2,-0.4 -4,-0.1 -3,-0.0 -3,-0.1 -0.753 32.1-138.1 -91.1 103.8 13.7 53.9 93.2 98 98 A P - 0 0 17 0, 0.0 3,-0.0 0, 0.0 -1,-0.0 -0.285 19.8-170.0 -59.3 135.5 13.1 51.4 95.9 99 99 A E S S+ 0 0 93 2,-0.0 2,-0.5 5,-0.0 -2,-0.0 0.485 77.8 68.3-101.6 -14.8 9.5 50.1 96.3 100 100 A I S S+ 0 0 15 4,-0.1 2,-0.3 -10,-0.1 19,-0.0 -0.898 71.3 135.9-103.5 130.8 10.4 48.4 99.5 101 101 A N >> - 0 0 57 -2,-0.5 4,-2.4 17,-0.0 3,-1.1 -0.978 65.8 -70.3-170.5 171.0 11.3 50.9 102.3 102 102 A S T 34 S+ 0 0 76 -2,-0.3 -11,-0.0 1,-0.3 6,-0.0 0.579 125.6 46.9 -47.9 -28.6 10.8 51.8 105.9 103 103 A T T 34 S+ 0 0 129 2,-0.2 -1,-0.3 1,-0.1 -3,-0.0 0.810 117.7 44.8 -85.1 -30.5 7.1 52.8 105.8 104 104 A T T <4 S+ 0 0 74 -3,-1.1 -2,-0.2 1,-0.3 -1,-0.1 0.876 133.0 16.0 -80.6 -33.4 6.3 49.7 103.7 105 105 A H S >< S+ 0 0 63 -4,-2.4 3,-0.6 1,-0.1 5,-0.3 -0.635 71.4 165.0-146.0 71.1 8.3 47.2 105.8 106 106 A P T 3 S+ 0 0 72 0, 0.0 -4,-0.1 0, 0.0 -1,-0.1 0.466 70.0 62.5 -69.0 -18.6 9.1 48.9 109.2 107 107 A G T 3 S+ 0 0 15 11,-0.1 -63,-0.2 -65,-0.1 -64,-0.1 0.843 90.3 80.6 -77.4 -32.2 10.2 45.9 111.1 108 108 A A S < S- 0 0 18 -3,-0.6 2,-0.6 -7,-0.1 -33,-0.1 -0.199 87.4-125.3 -68.9 164.1 13.1 45.3 108.8 109 109 A D + 0 0 44 2,-0.1 2,-2.2 -69,-0.0 5,-0.1 -0.570 29.8 179.3-119.4 72.2 16.1 47.6 109.5 110 110 A L + 0 0 19 -2,-0.6 2,-0.3 -5,-0.3 -8,-0.2 -0.543 26.2 151.5 -72.4 76.0 16.7 49.3 106.2 111 111 A R > - 0 0 92 -2,-2.2 3,-1.4 3,-0.1 -2,-0.1 -0.680 56.6 -24.5-109.9 156.5 19.7 51.3 107.5 112 112 A E T 3 S- 0 0 93 -2,-0.3 -22,-1.9 1,-0.2 -21,-0.3 -0.085 109.6 -55.7 41.5-132.3 22.6 52.6 105.5 113 113 A N T 3 S+ 0 0 29 -24,-0.2 -26,-0.3 -23,-0.1 2,-0.3 -0.215 90.1 144.1-129.9 27.2 23.1 50.4 102.4 114 114 A F < - 0 0 19 -3,-1.4 -35,-0.3 -5,-0.1 -3,-0.1 -0.646 56.9-101.0 -75.9 131.4 23.4 47.0 104.3 115 115 A e + 0 0 0 -37,-3.3 12,-0.3 -2,-0.3 -37,-0.2 -0.131 52.7 154.5 -52.3 143.1 21.9 43.8 102.8 116 116 A R - 0 0 0 10,-3.3 -42,-0.3 8,-0.1 -1,-0.1 0.627 40.0-138.1-140.8 -62.9 18.6 42.8 104.3 117 117 A N + 0 0 0 9,-0.2 -43,-0.1 7,-0.1 10,-0.0 0.963 27.7 169.3 79.3 74.4 15.7 40.6 102.8 118 118 A P S S+ 0 0 13 0, 0.0 -11,-0.1 0, 0.0 -10,-0.1 0.758 82.6 41.4 -78.1 -35.7 12.6 42.6 103.9 119 119 A D S S- 0 0 61 -19,-0.0 -47,-0.1 -14,-0.0 -2,-0.1 0.630 108.2-117.6 -86.3 -24.5 10.7 40.3 101.6 120 120 A G - 0 0 22 1,-0.1 -48,-0.1 -49,-0.1 -49,-0.1 0.912 36.4-169.4 78.4 45.1 12.2 36.8 102.1 121 121 A S > - 0 0 21 3,-0.2 3,-1.8 1,-0.1 -1,-0.1 -0.482 31.3-120.4 -64.0 142.9 13.4 36.4 98.6 122 122 A I T 3 S+ 0 0 149 1,-0.3 -1,-0.1 -2,-0.1 -2,-0.0 0.600 111.1 60.8 -69.8 -9.4 14.5 32.7 98.4 123 123 A T T 3 S- 0 0 76 1,-0.3 -1,-0.3 -52,-0.0 16,-0.2 0.274 106.6-131.1 -99.1 12.0 18.0 33.8 97.5 124 124 A G < + 0 0 5 -3,-1.8 -1,-0.3 14,-0.1 -3,-0.2 -0.276 55.2 12.9 84.1-166.0 18.5 35.7 100.8 125 125 A P + 0 0 8 0, 0.0 14,-3.3 0, 0.0 2,-0.2 -0.289 68.8 155.1 -60.6 130.3 19.6 39.0 102.0 126 126 A W E -E 138 0E 2 12,-0.3 -10,-3.3 -12,-0.1 2,-0.3 -0.540 23.4-163.6-134.3-169.2 20.0 41.6 99.2 127 127 A d E -E 137 0E 0 10,-0.7 10,-1.5 -12,-0.3 2,-0.3 -0.849 38.5 -83.3-174.5 168.3 19.9 45.4 98.7 128 128 A Y E -E 136 0E 0 -40,-0.4 -40,-3.0 -2,-0.3 8,-0.3 -0.694 49.9-129.7 -86.2 143.7 19.6 47.7 95.6 129 129 A T B -D 87 0D 0 6,-3.8 -42,-0.2 5,-0.5 -33,-0.1 -0.518 9.6-132.0 -96.3 166.7 22.8 48.3 93.7 130 130 A T S S+ 0 0 62 -44,-1.6 -43,-0.1 -2,-0.2 -1,-0.1 0.808 79.6 101.2 -80.2 -32.9 24.5 51.4 92.6 131 131 A S S > S- 0 0 31 -45,-0.3 3,-0.7 1,-0.2 -2,-0.2 -0.275 74.2-139.0 -54.7 123.9 25.1 50.1 89.0 132 132 A P T 3 S+ 0 0 109 0, 0.0 -1,-0.2 0, 0.0 3,-0.1 0.869 99.1 51.3 -54.4 -35.1 22.4 51.7 86.9 133 133 A T T 3 S+ 0 0 138 1,-0.2 2,-0.7 2,-0.1 -2,-0.1 0.731 103.7 54.7 -78.6 -23.9 21.9 48.3 85.1 134 134 A L < - 0 0 54 -3,-0.7 -5,-0.5 1,-0.2 -1,-0.2 -0.912 60.9-177.7-116.0 103.8 21.4 45.9 88.0 135 135 A R + 0 0 90 -2,-0.7 -6,-3.8 -7,-0.1 2,-0.3 0.994 67.4 7.7 -63.4 -67.9 18.6 47.1 90.4 136 136 A R E +E 128 0E 69 -8,-0.3 2,-0.3 -49,-0.1 -8,-0.2 -0.769 64.2 174.5-116.6 163.4 18.8 44.4 93.1 137 137 A E E -E 127 0E 49 -10,-1.5 -10,-0.7 -2,-0.3 -3,-0.0 -0.903 33.2-102.2-170.7 140.2 21.2 41.5 93.9 138 138 A E E -E 126 0E 73 -2,-0.3 -56,-1.9 -12,-0.2 -12,-0.3 -0.208 34.3-143.4 -62.2 151.1 21.8 38.8 96.6 139 139 A e B -C 81 0C 3 -14,-3.3 2,-0.9 -58,-0.2 -58,-0.2 -0.802 15.3-114.6-118.1 158.6 24.5 39.4 99.1 140 140 A S + 0 0 56 -60,-0.5 -60,-0.1 -2,-0.3 -16,-0.1 -0.832 45.4 165.0-101.3 97.1 26.9 36.8 100.8 141 141 A V - 0 0 19 -2,-0.9 -74,-0.1 -16,-0.1 -75,-0.1 -0.947 42.8 -95.8-119.4 141.8 26.2 36.6 104.4 142 142 A P - 0 0 87 0, 0.0 -75,-3.1 0, 0.0 2,-0.3 -0.157 42.7-123.5 -55.2 130.3 27.3 34.1 107.0 143 143 A V B -a 67 0A 103 -77,-0.3 -75,-0.2 1,-0.1 -77,-0.0 -0.631 26.3-100.4 -87.7 132.8 24.7 31.5 107.7 144 144 A c 0 0 20 -77,-4.4 -75,-0.2 -2,-0.3 -1,-0.1 -0.295 360.0 360.0 -52.4 118.0 23.3 30.8 111.1 145 145 A G 0 0 97 -77,-0.1 -1,-0.1 -3,-0.0 -77,-0.0 -0.978 360.0 360.0 131.8 360.0 25.1 27.7 112.3