==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-FEB-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 12-NOV-10 3PL1 . COMPND 2 MOLECULE: PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZASE); . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR S.PETRELLA,N.GELUS-ZIENTAL,C.MAYER,W.SOUGAKOFF . 185 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8632.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 121 65.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 35 18.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 11 5.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 20 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 32 17.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 1 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A M 0 0 85 0, 0.0 125,-2.3 0, 0.0 126,-1.7 0.000 360.0 360.0 360.0 -35.2 -7.8 -41.8 12.7 2 2 A R E -a 127 0A 56 123,-0.2 40,-1.5 124,-0.2 41,-1.3 -0.954 360.0-178.6-117.9 134.0 -8.0 -38.7 10.3 3 3 A A E -ab 128 43A 0 124,-2.2 126,-2.1 -2,-0.4 2,-0.4 -0.960 22.5-135.9-126.5 153.8 -5.3 -35.9 10.2 4 4 A L E -ab 129 44A 0 39,-2.2 41,-2.2 -2,-0.3 2,-0.5 -0.914 16.6-158.4-103.2 132.4 -5.0 -32.7 8.2 5 5 A I E -ab 130 45A 0 124,-2.8 126,-2.1 -2,-0.4 2,-0.7 -0.967 3.5-157.1-113.7 111.9 -1.5 -32.0 6.7 6 6 A I E -ab 131 46A 1 39,-2.5 41,-2.3 -2,-0.5 2,-0.5 -0.814 16.9-146.7 -91.9 112.2 -0.8 -28.3 5.9 7 7 A V E -ab 132 47A 0 124,-3.0 126,-2.4 -2,-0.7 41,-0.1 -0.695 52.3 -38.8 -95.6 119.1 1.9 -28.1 3.2 8 8 A D + 0 0 5 39,-0.8 2,-1.8 -2,-0.5 -1,-0.2 0.705 62.9 168.0 50.5 45.6 4.5 -25.3 2.9 9 9 A V + 0 0 1 38,-0.4 73,-1.9 -3,-0.3 2,-0.2 -0.534 32.8 142.1 -89.3 73.5 2.4 -22.3 3.8 10 10 A Q B > -H 81 0B 0 -2,-1.8 3,-1.5 71,-0.3 4,-0.3 -0.749 66.1-107.2-123.8 153.3 5.5 -20.1 4.1 11 11 A N G > S+ 0 0 45 69,-2.4 3,-1.7 66,-0.4 6,-0.3 0.827 114.3 56.9 -46.1 -47.9 6.5 -16.5 3.3 12 12 A D G 3 S+ 0 0 23 66,-2.0 7,-2.5 1,-0.3 -1,-0.2 0.713 107.2 50.6 -64.4 -17.5 8.8 -17.4 0.3 13 13 A F G < S+ 0 0 25 -3,-1.5 8,-1.3 65,-0.3 -1,-0.3 0.337 104.8 70.8-100.9 3.1 5.8 -19.1 -1.4 14 14 A C S X S- 0 0 2 -3,-1.7 3,-2.7 -4,-0.3 5,-0.1 -0.677 103.9 -57.2-112.7 171.8 3.4 -16.1 -1.0 15 15 A E T 3 S+ 0 0 90 6,-0.3 -1,-0.1 1,-0.3 3,-0.1 -0.153 128.4 23.3 -45.2 128.4 3.2 -12.6 -2.5 16 16 A G T 3 S+ 0 0 88 1,-0.3 -1,-0.3 -4,-0.1 -4,-0.1 0.065 100.9 120.4 95.4 -23.9 6.5 -10.7 -1.9 17 17 A G S X S- 0 0 17 -3,-2.7 3,-1.4 -6,-0.3 -1,-0.3 -0.219 78.8-112.5 -78.9 164.3 8.4 -14.1 -1.5 18 18 A S T 3 S+ 0 0 54 1,-0.3 -5,-0.1 -3,-0.1 -1,-0.1 0.817 122.2 30.5 -65.0 -26.4 11.3 -15.3 -3.6 19 19 A L T 3 S- 0 0 27 -7,-2.5 -1,-0.3 -5,-0.1 -4,-0.1 -0.276 91.6-175.4-121.3 42.4 9.0 -18.1 -5.0 20 20 A A < - 0 0 52 -3,-1.4 2,-0.6 -6,-0.1 -6,-0.2 -0.119 12.7-162.2 -42.9 122.1 5.7 -16.2 -4.8 21 21 A V > - 0 0 11 -8,-1.3 3,-2.0 143,-0.0 -6,-0.3 -0.983 28.1-121.4-105.5 107.8 2.5 -18.2 -5.8 22 22 A T T 3 S+ 0 0 126 -2,-0.6 140,-0.1 1,-0.3 -8,-0.0 -0.309 101.4 31.3 -46.5 128.7 -0.3 -15.8 -6.5 23 23 A G T 3> S+ 0 0 26 138,-0.1 4,-2.2 4,-0.0 -1,-0.3 0.308 87.1 113.8 98.9 -3.6 -3.2 -16.6 -4.1 24 24 A G H <> S+ 0 0 0 -3,-2.0 4,-1.8 2,-0.2 -10,-0.1 0.959 76.1 45.9 -65.4 -50.4 -0.8 -17.7 -1.4 25 25 A A H > S+ 0 0 28 -4,-0.2 4,-1.4 1,-0.2 3,-0.5 0.949 115.7 46.8 -56.8 -56.6 -1.6 -14.9 1.1 26 26 A A H > S+ 0 0 55 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.871 109.9 54.9 -48.4 -47.4 -5.4 -15.4 0.6 27 27 A L H X S+ 0 0 11 -4,-2.2 4,-2.1 2,-0.2 -1,-0.2 0.844 101.0 58.6 -58.1 -36.1 -5.0 -19.2 0.9 28 28 A A H X S+ 0 0 0 -4,-1.8 4,-1.8 -3,-0.5 58,-0.2 0.921 111.1 41.8 -62.7 -39.8 -3.2 -18.8 4.4 29 29 A R H < S+ 0 0 143 -4,-1.4 5,-0.2 2,-0.2 -1,-0.2 0.862 109.6 56.9 -82.0 -28.0 -6.3 -17.0 5.8 30 30 A A H X S+ 0 0 37 -4,-2.0 4,-0.7 1,-0.2 -1,-0.2 0.845 106.8 51.4 -63.2 -36.8 -8.8 -19.3 4.1 31 31 A I H < S+ 0 0 0 -4,-2.1 3,-0.2 -5,-0.2 5,-0.2 0.940 103.1 64.0 -67.5 -47.6 -7.1 -22.3 5.9 32 32 A S T < S+ 0 0 7 -4,-1.8 2,-1.7 1,-0.2 3,-0.2 -0.364 106.9 33.3 -58.5 157.1 -7.4 -20.4 9.3 33 33 A D T > S+ 0 0 74 4,-0.1 4,-0.8 -2,-0.0 2,-0.3 0.135 108.3 71.8 68.6 -34.5 -11.1 -20.1 9.9 34 34 A Y T < S+ 0 0 29 -2,-1.7 2,-2.5 -4,-0.7 5,-0.3 -0.515 99.3 44.0 -69.8-179.5 -11.4 -23.4 8.2 35 35 A L T 4 S+ 0 0 35 3,-2.1 4,-0.2 -2,-0.3 -3,-0.1 -0.074 115.2 55.0 72.3 -49.9 -9.8 -25.1 11.3 36 36 A A T 4 S+ 0 0 66 -2,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.694 117.8 29.8 -78.2 -31.7 -12.3 -22.7 13.1 37 37 A E S < S+ 0 0 139 1,-0.9 2,-0.3 -4,-0.8 -3,-0.1 0.835 130.3 14.7 -90.9 -92.1 -15.4 -24.0 11.2 38 38 A A + 0 0 44 1,-0.2 -3,-2.1 -5,-0.1 -1,-0.9 -0.785 60.3 144.4 -97.1 160.6 -14.7 -27.6 10.4 39 39 A A + 0 0 39 -2,-0.3 -1,-0.2 -5,-0.3 3,-0.1 0.110 5.7 161.7 99.1-174.9 -12.5 -29.3 11.8 40 40 A D + 0 0 151 1,-0.2 2,-0.5 -2,-0.1 3,-0.1 0.816 40.4 140.6 77.3 35.7 -13.3 -33.0 12.4 41 41 A Y - 0 0 35 1,-0.1 -1,-0.2 -6,-0.1 -38,-0.2 -0.944 49.7-160.5-112.0 126.2 -9.6 -33.9 12.7 42 42 A H S S+ 0 0 125 -40,-1.5 2,-0.3 -2,-0.5 -39,-0.2 0.902 88.0 9.1 -59.3 -39.2 -8.1 -36.3 15.2 43 43 A H E -b 3 0A 40 -41,-1.3 -39,-2.2 -3,-0.1 2,-0.4 -0.994 60.8-156.3-144.4 149.9 -4.7 -34.4 14.5 44 44 A V E +b 4 0A 13 45,-0.3 47,-3.4 -2,-0.3 48,-0.7 -0.993 22.0 165.5-127.5 124.2 -3.3 -31.3 12.6 45 45 A V E -bc 5 92A 0 -41,-2.2 -39,-2.5 -2,-0.4 2,-0.3 -0.862 17.8-151.0-131.1 161.3 0.4 -31.1 11.4 46 46 A A E -bc 6 93A 0 46,-2.2 48,-2.6 -2,-0.3 2,-0.3 -0.951 4.4-147.0-131.5 158.7 2.3 -28.8 9.0 47 47 A T E -bc 7 94A 0 -41,-2.3 -39,-0.8 -2,-0.3 -38,-0.4 -0.858 12.2-165.5-116.7 158.5 5.4 -29.2 6.8 48 48 A K E - c 0 95A 19 46,-2.3 48,-1.7 -2,-0.3 2,-0.3 -0.982 23.9-129.0-143.1 133.0 8.0 -26.6 6.0 49 49 A D E + c 0 96A 7 -2,-0.3 2,-0.3 46,-0.2 48,-0.2 -0.581 38.0 178.5 -65.2 134.3 10.7 -26.4 3.3 50 50 A F - 0 0 56 46,-2.4 2,-0.5 -2,-0.3 23,-0.2 -0.753 8.4-169.0-154.9 98.3 13.9 -25.5 5.4 51 51 A H B +i 73 0C 1 21,-2.8 23,-2.5 -2,-0.3 47,-0.2 -0.820 24.4 158.0-105.4 126.1 17.3 -25.2 3.8 52 52 A I S S- 0 0 87 46,-1.9 47,-0.2 -2,-0.5 -1,-0.2 0.772 90.4 -16.8-102.3 -58.0 20.7 -24.9 5.6 53 53 A D + 0 0 104 45,-3.1 45,-0.1 44,-0.2 44,-0.0 -0.486 67.0 162.0-151.5 90.8 22.8 -26.0 2.8 54 54 A P > - 0 0 8 0, 0.0 3,-1.8 0, 0.0 47,-0.3 0.152 31.4-156.4 -91.8 14.0 21.1 -27.8 -0.1 55 55 A G G > S+ 0 0 38 1,-0.3 3,-1.9 2,-0.2 45,-0.1 -0.198 73.8 16.3 58.5-128.2 23.9 -27.3 -2.7 56 56 A D G 3 S+ 0 0 149 1,-0.3 -1,-0.3 11,-0.1 12,-0.2 0.591 106.6 84.3 -60.0 -18.9 22.7 -27.5 -6.4 57 57 A H G < S+ 0 0 13 -3,-1.8 11,-1.5 10,-0.2 2,-0.4 0.725 93.1 52.2 -52.4 -28.0 19.0 -27.0 -5.4 58 58 A F B < S+j 68 0D 44 -3,-1.9 2,-0.3 9,-0.2 3,-0.0 -0.901 71.6 172.3-110.6 147.2 19.8 -23.3 -5.4 59 59 A S - 0 0 38 9,-2.0 -3,-0.0 -2,-0.4 8,-0.0 -0.991 42.2-138.3-152.7 150.8 21.4 -21.4 -8.3 60 60 A G S S+ 0 0 79 -2,-0.3 -1,-0.1 1,-0.2 7,-0.0 0.672 114.2 40.1 -74.4 -20.0 22.2 -17.9 -9.5 61 61 A T S S- 0 0 128 7,-0.1 -1,-0.2 -3,-0.0 6,-0.0 -0.462 93.4-171.6-123.5 57.5 20.9 -19.0 -13.0 62 62 A P - 0 0 32 0, 0.0 6,-0.1 0, 0.0 -5,-0.0 -0.141 25.8-161.1 -67.7 146.7 17.8 -21.1 -11.9 63 63 A D - 0 0 86 4,-0.1 5,-0.2 5,-0.0 0, 0.0 0.406 31.4-130.7 -99.6 2.5 15.8 -23.2 -14.3 64 64 A Y S S+ 0 0 133 3,-1.6 4,-0.1 1,-0.1 0, 0.0 0.721 97.1 69.9 49.0 26.0 12.6 -23.6 -12.1 65 65 A S S S- 0 0 95 2,-0.5 -1,-0.1 0, 0.0 3,-0.1 0.538 122.9 -7.7-128.1 -50.7 12.7 -27.3 -12.7 66 66 A S S S+ 0 0 71 1,-0.2 2,-0.3 -10,-0.0 35,-0.1 0.468 131.5 50.7-121.9 -8.1 15.8 -28.7 -10.8 67 67 A S - 0 0 15 -6,-0.0 -3,-1.6 -8,-0.0 -2,-0.5 -0.970 66.0-177.6-133.9 143.5 17.4 -25.4 -9.6 68 68 A W B -j 58 0D 44 -11,-1.5 -9,-2.0 -2,-0.3 3,-0.1 -0.924 35.4 -95.1-134.5 156.5 15.7 -22.5 -7.8 69 69 A P - 0 0 24 0, 0.0 -9,-0.1 0, 0.0 -51,-0.0 -0.488 69.5 -76.5 -67.8 154.0 16.5 -19.0 -6.4 70 70 A P + 0 0 73 0, 0.0 2,-0.3 0, 0.0 3,-0.1 -0.252 68.6 163.7 -48.3 136.1 17.3 -19.3 -2.7 71 71 A H + 0 0 5 1,-0.1 -20,-0.2 -3,-0.1 8,-0.1 -0.982 49.2 17.7-154.7 153.1 14.2 -19.8 -0.6 72 72 A C S S- 0 0 0 -2,-0.3 -21,-2.8 1,-0.2 2,-0.4 0.852 75.3-179.8 51.3 43.8 13.1 -20.9 2.9 73 73 A V B > -i 51 0C 44 -23,-0.2 3,-2.0 1,-0.1 6,-0.4 -0.644 36.1-102.2 -77.9 127.3 16.7 -20.3 4.2 74 74 A S T 3 S+ 0 0 43 -23,-2.5 -1,-0.1 -2,-0.4 -24,-0.1 -0.257 107.4 21.6 -52.9 126.1 17.2 -21.2 7.9 75 75 A G T 3 S+ 0 0 84 1,-0.3 -1,-0.3 2,-0.0 -23,-0.0 0.480 104.0 101.4 91.0 3.6 17.2 -17.9 10.0 76 76 A T S X S- 0 0 55 -3,-2.0 3,-1.0 1,-0.1 4,-0.3 -0.814 81.1-115.3-111.7 161.0 15.4 -15.8 7.4 77 77 A P G > S+ 0 0 95 0, 0.0 3,-1.5 0, 0.0 -66,-0.4 0.813 106.7 72.0 -61.6 -32.6 11.7 -14.6 7.3 78 78 A G G 3 S+ 0 0 8 1,-0.3 -66,-2.0 -67,-0.2 -65,-0.3 0.804 94.1 55.9 -50.4 -31.2 11.1 -16.6 4.0 79 79 A A G < S+ 0 0 2 -3,-1.0 -1,-0.3 -6,-0.4 3,-0.1 0.701 91.5 91.4 -82.7 -16.1 11.2 -19.8 6.0 80 80 A D S < S- 0 0 85 -3,-1.5 -69,-2.4 -4,-0.3 -68,-0.2 -0.333 87.5 -86.6 -77.4 157.7 8.4 -18.8 8.5 81 81 A F B -H 10 0B 39 -71,-0.3 -71,-0.3 1,-0.1 -1,-0.1 -0.292 53.2 -97.4 -50.4 137.0 4.6 -19.4 8.4 82 82 A H - 0 0 31 -73,-1.9 -1,-0.1 1,-0.1 -73,-0.1 -0.379 37.0-119.7 -56.0 137.1 2.7 -16.8 6.5 83 83 A P S S+ 0 0 110 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.755 103.8 67.4 -63.5 -22.1 1.4 -14.4 9.3 84 84 A S S S+ 0 0 32 2,-0.1 -55,-0.2 -59,-0.1 -58,-0.1 -0.036 78.6 85.7 -65.5-171.1 -2.3 -15.1 8.4 85 85 A L S S- 0 0 9 -57,-0.2 2,-0.1 1,-0.0 -56,-0.1 0.916 81.5-123.7 77.3 80.3 -2.6 -18.7 9.3 86 86 A D - 0 0 96 -58,-0.2 3,-0.1 1,-0.2 -2,-0.1 -0.463 20.6-166.7 -55.3 129.6 -3.5 -19.4 13.0 87 87 A T > + 0 0 84 -2,-0.1 3,-1.9 1,-0.1 -1,-0.2 0.520 63.4 98.3-101.5 -16.4 -0.8 -21.7 14.3 88 88 A S T 3 S+ 0 0 123 1,-0.2 -1,-0.1 3,-0.0 -2,-0.0 0.800 82.8 47.7 -32.6 -47.6 -2.8 -22.6 17.5 89 89 A A T 3 S+ 0 0 45 -3,-0.1 2,-0.6 -46,-0.0 -45,-0.3 0.557 82.7 107.9 -84.0 -6.8 -4.1 -25.9 16.1 90 90 A I < - 0 0 24 -3,-1.9 -45,-0.2 1,-0.2 3,-0.1 -0.605 42.3-176.2 -89.1 114.8 -0.8 -27.3 14.8 91 91 A E + 0 0 100 -47,-3.4 2,-0.3 -2,-0.6 -46,-0.2 0.813 67.0 11.2 -81.1 -34.7 0.5 -30.2 16.9 92 92 A A E -c 45 0A 11 -48,-0.7 -46,-2.2 18,-0.0 2,-0.5 -0.995 59.4-143.7-147.9 145.1 3.8 -30.8 15.1 93 93 A V E -c 46 0A 29 -2,-0.3 2,-0.5 -48,-0.2 18,-0.3 -0.921 12.9-156.0-105.2 125.9 6.0 -29.2 12.4 94 94 A F E -c 47 0A 0 -48,-2.6 -46,-2.3 -2,-0.5 2,-0.4 -0.905 9.6-161.1-104.3 115.6 7.9 -31.5 9.8 95 95 A Y E +cD 48 109A 75 14,-2.9 14,-2.3 -2,-0.5 2,-0.3 -0.770 12.8 175.8 -98.6 137.1 11.1 -29.8 8.3 96 96 A K E +c 49 0A 7 -48,-1.7 -46,-2.4 -2,-0.4 6,-0.2 -0.969 51.5 41.1-136.2 155.8 12.6 -31.2 5.0 97 97 A G + 0 0 7 -2,-0.3 3,-0.5 10,-0.2 -45,-0.4 0.573 55.6 144.3 89.8 16.6 15.5 -30.1 2.8 98 98 A A S S+ 0 0 33 1,-0.2 -45,-3.1 -47,-0.2 -46,-1.9 0.925 92.1 5.4 -52.1 -48.6 18.2 -29.1 5.4 99 99 A Y S S+ 0 0 160 -47,-0.2 2,-0.3 -48,-0.1 -1,-0.2 0.189 134.3 40.0-118.7 18.3 21.1 -30.4 3.2 100 100 A T S S- 0 0 81 -3,-0.5 2,-0.3 -45,-0.1 -45,-0.1 -0.994 88.4 -88.1-161.7 150.7 19.2 -31.4 0.1 101 101 A G - 0 0 13 -47,-0.3 2,-0.4 -2,-0.3 -4,-0.2 -0.578 48.7-152.4 -61.2 129.0 16.4 -30.4 -2.4 102 102 A A + 0 0 11 -2,-0.3 3,-0.1 -6,-0.2 36,-0.1 -0.905 23.6 178.8-113.7 142.4 13.1 -31.9 -1.0 103 103 A Y + 0 0 142 -2,-0.4 2,-0.3 1,-0.2 38,-0.2 0.713 62.8 38.2-107.8 -24.4 10.0 -32.9 -3.0 104 104 A S > - 0 0 0 37,-0.2 3,-2.2 1,-0.1 4,-0.2 -0.967 67.8-126.4-138.9 141.5 7.5 -34.3 -0.5 105 105 A G G > S+ 0 0 0 33,-0.5 3,-2.3 -2,-0.3 11,-0.3 0.780 106.7 73.9 -53.1 -23.7 6.2 -33.7 3.0 106 106 A F G 3 S+ 0 0 29 1,-0.3 11,-0.3 10,-0.1 -1,-0.3 0.636 86.8 62.0 -75.7 -5.8 7.0 -37.4 3.6 107 107 A E G < S+ 0 0 88 -3,-2.2 -1,-0.3 8,-0.1 -10,-0.2 0.551 85.8 108.8 -85.0 -8.1 10.7 -36.4 3.7 108 108 A G < - 0 0 0 -3,-2.3 8,-1.9 -4,-0.2 2,-0.3 -0.388 49.9-163.2 -78.5 153.3 10.1 -34.2 6.7 109 109 A V B -DE 95 115A 67 -14,-2.3 -14,-2.9 6,-0.2 5,-0.2 -0.964 15.2-131.1-125.7 142.4 11.2 -34.8 10.2 110 110 A D - 0 0 16 4,-2.4 -16,-0.1 -2,-0.3 -18,-0.0 -0.236 45.0 -80.2 -85.4 179.4 10.0 -33.1 13.4 111 111 A E S S+ 0 0 171 -18,-0.3 2,-0.1 2,-0.1 -17,-0.1 0.695 120.9 47.3 -60.0 -23.6 12.3 -31.6 16.1 112 112 A N S S- 0 0 110 2,-0.1 0, 0.0 0, 0.0 0, 0.0 -0.243 125.3 -72.3 -88.3-162.8 13.0 -35.0 17.8 113 113 A G S S+ 0 0 68 -2,-0.1 -2,-0.1 -4,-0.1 0, 0.0 0.670 86.0 138.1 -60.2 -5.0 14.0 -37.7 15.4 114 114 A T - 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