==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 29-JUL-03 1Q39 . COMPND 2 MOLECULE: ENDONUCLEASE VIII; . SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; . AUTHOR G.GOLAN,D.O.ZHARKOV,H.FEINBERG,A.S.FERNANDES,E.I.ZAIKA,J.H.K . 257 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13281.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 177 68.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 46 17.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 15.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 53 20.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 0 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A P 0 0 148 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -80.7 8.7 5.1 28.1 2 5 A E + 0 0 63 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.132 360.0 118.7-161.7 15.2 6.0 3.5 30.3 3 6 A I > + 0 0 89 1,-0.2 2,-2.4 2,-0.1 3,-1.0 0.627 54.1 93.5 -64.5 -13.7 6.4 5.5 33.5 4 7 A R T 3 + 0 0 41 1,-0.2 -1,-0.2 2,-0.1 42,-0.0 -0.507 57.9 96.3 -79.0 68.5 2.8 6.5 32.8 5 8 A R T 3> + 0 0 46 -2,-2.4 4,-1.8 2,-0.1 -1,-0.2 0.529 63.4 67.8-128.8 -29.3 1.6 3.7 35.0 6 9 A A H <> S+ 0 0 50 -3,-1.0 4,-1.4 1,-0.2 -2,-0.1 0.852 100.3 53.7 -63.0 -35.5 1.0 5.4 38.4 7 10 A A H > S+ 0 0 1 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.843 105.0 53.3 -67.5 -36.8 -1.9 7.3 36.8 8 11 A D H > S+ 0 0 60 1,-0.2 4,-3.6 2,-0.2 -2,-0.2 0.885 104.1 56.9 -67.2 -39.2 -3.5 4.0 35.6 9 12 A N H < S+ 0 0 99 -4,-1.8 4,-0.4 1,-0.2 -1,-0.2 0.908 110.6 43.0 -58.9 -42.3 -3.3 2.7 39.2 10 13 A L H >X>S+ 0 0 3 -4,-1.4 4,-2.7 2,-0.2 3,-0.8 0.917 116.7 45.9 -71.2 -43.7 -5.3 5.6 40.5 11 14 A E H 3X5S+ 0 0 19 -4,-2.4 4,-2.0 1,-0.3 -2,-0.2 0.955 110.5 54.5 -63.1 -46.9 -7.8 5.6 37.6 12 15 A A H 3<5S+ 0 0 84 -4,-3.6 -1,-0.3 1,-0.2 -2,-0.2 0.635 115.7 41.5 -61.4 -13.5 -8.2 1.8 38.0 13 16 A A H <45S+ 0 0 6 -3,-0.8 81,-0.3 -4,-0.4 -2,-0.2 0.865 134.3 3.5-101.6 -50.2 -9.0 2.4 41.6 14 17 A I H ><5S+ 0 0 3 -4,-2.7 3,-1.0 -5,-0.1 27,-0.6 0.478 84.2 129.5-120.9 -0.2 -11.3 5.4 41.9 15 18 A K B 3<> S- 0 0 34 60,-0.4 3,-1.7 1,-0.2 4,-0.9 -0.533 73.8-144.3 -71.1 123.5 -3.1 21.8 53.4 27 30 A P G >4 S+ 0 0 100 0, 0.0 3,-0.7 0, 0.0 4,-0.5 0.846 98.0 62.9 -53.5 -40.7 -5.5 24.4 54.9 28 31 A Q G 34 S+ 0 0 125 1,-0.2 3,-0.2 2,-0.1 -2,-0.1 0.767 107.8 45.5 -57.5 -25.4 -5.7 26.3 51.7 29 32 A L G X4 S+ 0 0 9 -3,-1.7 3,-3.0 1,-0.2 4,-0.4 0.656 83.0 90.0 -92.5 -21.3 -7.3 23.2 50.2 30 33 A K G X< S+ 0 0 81 -4,-0.9 3,-1.3 -3,-0.7 4,-0.5 0.783 77.1 72.3 -46.2 -30.2 -9.8 22.3 52.9 31 34 A T G 3 S+ 0 0 98 -4,-0.5 -1,-0.3 1,-0.2 4,-0.2 0.560 94.3 51.5 -64.9 -10.1 -12.2 24.5 51.0 32 35 A Y G <> S+ 0 0 57 -3,-3.0 4,-1.0 2,-0.1 -1,-0.2 0.541 86.9 86.2-104.3 -9.6 -12.6 21.9 48.3 33 36 A Q H X> S+ 0 0 40 -3,-1.3 3,-1.3 -4,-0.4 4,-0.8 0.971 93.9 36.4 -56.2 -65.3 -13.4 18.9 50.4 34 37 A S H >4 S+ 0 0 86 -4,-0.5 3,-0.5 1,-0.3 -1,-0.2 0.821 110.8 64.9 -60.3 -30.6 -17.2 19.2 50.8 35 38 A Q H 34 S+ 0 0 101 1,-0.2 -1,-0.3 -4,-0.2 -2,-0.2 0.789 102.3 48.9 -63.6 -27.7 -17.5 20.5 47.3 36 39 A L H X< S+ 0 0 0 -3,-1.3 3,-2.5 -4,-1.0 -17,-0.4 0.654 77.4 111.3 -88.6 -19.4 -16.2 17.1 45.9 37 40 A I T << S+ 0 0 79 -4,-0.8 -17,-0.2 -3,-0.5 3,-0.1 -0.405 87.8 24.1 -59.0 127.0 -18.5 14.8 47.8 38 41 A G T 3 S+ 0 0 51 -19,-2.2 -1,-0.3 1,-0.5 -18,-0.1 -0.054 106.6 102.3 105.6 -29.8 -20.8 13.3 45.2 39 42 A Q < - 0 0 57 -3,-2.5 -20,-4.2 -20,-0.2 -1,-0.5 -0.254 56.9-151.1 -79.7 169.1 -18.3 14.0 42.4 40 43 A H B -E 18 0B 65 -22,-0.3 16,-2.3 -3,-0.1 2,-0.6 -0.930 26.1 -96.2-139.3 164.5 -16.0 11.5 40.8 41 44 A V E -aB 15 55A 1 -27,-0.6 -25,-2.3 -24,-0.5 14,-0.3 -0.735 27.5-167.6 -82.6 118.4 -12.6 11.4 39.1 42 45 A T E - 0 0 53 12,-1.4 2,-0.3 -2,-0.6 -1,-0.2 0.932 64.7 -46.7 -71.3 -44.5 -13.1 11.6 35.3 43 46 A H E - B 0 54A 48 11,-0.8 11,-2.4 -3,-0.1 2,-0.5 -0.976 48.0-108.6-173.8 174.4 -9.5 10.6 34.7 44 47 A V E - B 0 53A 1 -2,-0.3 9,-0.2 9,-0.2 2,-0.2 -0.923 28.5-161.0-125.8 105.5 -5.9 11.2 35.6 45 48 A E E - B 0 52A 22 7,-2.5 7,-3.2 -2,-0.5 2,-0.3 -0.548 13.0-136.6 -82.5 145.1 -3.7 13.0 33.0 46 49 A T E + B 0 51A 14 5,-0.2 78,-0.4 -2,-0.2 2,-0.2 -0.820 20.5 179.9-104.1 147.1 0.1 12.7 33.2 47 50 A R E > - B 0 50A 17 3,-1.9 3,-1.5 -2,-0.3 2,-0.3 -0.696 63.7 -56.3-148.8 89.3 2.4 15.6 32.7 48 51 A G T 3 S- 0 0 50 74,-0.3 -1,-0.3 1,-0.3 76,-0.1 -0.610 120.2 -25.0 70.4-134.0 6.1 14.9 33.0 49 52 A K T 3 S+ 0 0 176 -2,-0.3 16,-0.6 -3,-0.1 17,-0.3 0.120 123.8 97.5 -96.6 23.6 6.4 13.4 36.5 50 53 A A E < -BC 47 64A 1 -3,-1.5 -3,-1.9 14,-0.2 2,-0.4 -0.659 64.0-136.2-107.8 166.1 3.3 15.1 37.7 51 54 A L E -BC 46 63A 14 12,-2.1 12,-1.3 -2,-0.2 2,-0.7 -0.978 6.6-163.4-127.0 128.9 -0.3 14.0 38.0 52 55 A L E -BC 45 62A 0 -7,-3.2 -7,-2.5 -2,-0.4 2,-0.8 -0.897 10.1-167.0-110.9 102.6 -3.5 15.9 37.0 53 56 A T E -BC 44 61A 1 8,-2.7 8,-2.8 -2,-0.7 2,-0.3 -0.813 11.3-156.3 -92.5 107.5 -6.5 14.3 38.6 54 57 A H E -BC 43 60A 24 -11,-2.4 -12,-1.4 -2,-0.8 -11,-0.8 -0.610 4.1-155.7 -86.0 141.0 -9.6 15.7 37.0 55 58 A F E > -B 41 0A 5 4,-2.6 3,-1.8 -2,-0.3 -14,-0.2 -0.799 30.7-107.6-115.1 159.6 -13.0 15.7 38.8 56 59 A S T 3 S+ 0 0 44 -16,-2.3 -15,-0.1 -2,-0.3 -2,-0.0 0.507 114.6 62.3 -61.4 -6.2 -16.5 15.8 37.4 57 60 A N T 3 S- 0 0 44 -17,-0.2 -1,-0.3 2,-0.1 3,-0.1 0.254 120.8-101.3-105.6 12.3 -16.9 19.4 38.5 58 61 A D S < S+ 0 0 61 -3,-1.8 2,-0.2 1,-0.3 -2,-0.1 0.439 82.6 129.9 83.4 2.0 -14.1 20.8 36.3 59 62 A L - 0 0 10 49,-0.1 -4,-2.6 -4,-0.1 2,-0.4 -0.497 41.9-156.0 -83.7 158.6 -11.6 21.0 39.2 60 63 A T E -CD 54 107A 2 47,-1.4 47,-3.2 -6,-0.2 2,-0.7 -0.944 10.2-146.7-143.7 119.6 -8.2 19.5 38.9 61 64 A L E -CD 53 106A 0 -8,-2.8 -8,-2.7 -2,-0.4 2,-0.3 -0.755 17.5-161.8 -88.4 115.4 -5.8 18.3 41.5 62 65 A Y E +CD 52 105A 4 43,-3.1 43,-2.4 -2,-0.7 2,-0.3 -0.752 15.6 171.8 -91.4 138.6 -2.2 18.9 40.5 63 66 A S E -CD 51 104A 1 -12,-1.3 -12,-2.1 -2,-0.3 2,-0.6 -0.917 20.1-168.4-155.8 126.1 0.5 16.9 42.3 64 67 A H E -CD 50 103A 5 39,-2.6 39,-0.8 -2,-0.3 38,-0.6 -0.947 8.1-162.0-117.4 114.4 4.2 16.4 41.9 65 68 A N >> + 0 0 37 -16,-0.6 4,-2.5 -2,-0.6 3,-0.7 0.740 26.1 171.1 -64.3 -24.1 5.8 13.6 44.0 66 69 A Q T 34 - 0 0 113 -17,-0.3 -1,-0.2 1,-0.2 35,-0.1 -0.276 67.0 -17.0 51.8-118.0 9.2 15.1 43.4 67 70 A L T 34 S+ 0 0 138 -3,-0.2 -1,-0.2 -2,-0.1 -2,-0.1 0.868 144.7 12.2 -88.2 -38.8 11.6 13.2 45.7 68 71 A Y T <4 S+ 0 0 166 -3,-0.7 33,-0.2 32,-0.2 -2,-0.2 0.711 84.2 122.6-115.6 -23.9 9.3 11.5 48.2 69 72 A G < + 0 0 14 -4,-2.5 2,-0.3 31,-0.3 31,-0.2 0.011 33.0 174.2 -42.3 142.7 5.7 11.6 47.2 70 73 A V E -G 99 0C 29 29,-1.8 29,-2.1 2,-0.0 2,-0.2 -0.873 22.3-146.3-158.9 122.0 3.9 8.3 46.8 71 74 A W E -G 98 0C 27 -2,-0.3 2,-0.3 27,-0.2 27,-0.2 -0.507 18.0-168.3 -83.0 158.4 0.4 7.3 46.1 72 75 A R E -G 97 0C 119 25,-1.3 25,-2.7 -2,-0.2 2,-0.5 -0.966 13.5-144.1-150.2 129.1 -1.1 4.2 47.6 73 76 A V E +G 96 0C 64 -2,-0.3 23,-0.2 23,-0.2 2,-0.2 -0.822 33.0 154.0 -98.7 132.7 -4.3 2.3 46.9 74 77 A V E -G 95 0C 32 21,-2.9 21,-1.5 -2,-0.5 2,-0.4 -0.628 43.2 -81.7-136.2-166.3 -6.1 0.8 49.8 75 78 A D E > -G 94 0C 92 19,-0.2 2,-1.1 -2,-0.2 3,-1.0 -0.865 51.5 -93.3-109.6 143.6 -9.6 -0.3 50.9 76 79 A T T 3 S+ 0 0 49 17,-3.0 3,-0.1 -2,-0.4 18,-0.1 -0.341 123.6 23.4 -54.4 94.8 -12.2 2.1 52.3 77 80 A G T 3 S+ 0 0 65 -2,-1.1 -1,-0.3 1,-0.6 17,-0.1 -0.396 87.7 113.5 141.3 -56.4 -11.2 1.4 55.8 78 81 A E < 0 0 50 -3,-1.0 -1,-0.6 1,-0.1 -4,-0.1 -0.241 360.0 360.0 -46.7 120.6 -7.6 0.2 55.6 79 82 A E 0 0 205 -3,-0.1 -4,-0.1 -5,-0.1 -1,-0.1 -0.376 360.0 360.0-104.5 360.0 -5.8 3.0 57.4 80 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 81 85 A T 0 0 133 0, 0.0 2,-2.1 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 94.0 2.3 4.6 58.6 82 86 A T + 0 0 149 1,-0.1 2,-0.2 0, 0.0 0, 0.0 -0.041 360.0 90.1 65.1 -36.5 5.2 6.9 59.5 83 87 A R S S- 0 0 104 -2,-2.1 2,-0.6 1,-0.0 -1,-0.1 -0.567 87.3-112.2 -82.5 155.8 4.9 9.0 56.3 84 88 A V - 0 0 78 -2,-0.2 16,-2.5 -3,-0.1 17,-0.1 -0.822 25.7-128.1 -97.9 125.2 2.6 11.9 56.6 85 89 A L E + H 0 99C 44 -2,-0.6 14,-0.2 14,-0.2 3,-0.1 -0.360 30.0 170.6 -66.9 143.9 -0.7 11.9 54.7 86 90 A R E + 0 0 61 12,-2.9 -61,-2.5 1,-0.4 -60,-0.4 0.651 64.8 24.2-120.5 -42.1 -1.5 14.8 52.4 87 91 A V E -FH 24 98C 0 11,-1.5 11,-2.2 -63,-0.2 -1,-0.4 -0.987 52.0-175.5-135.4 143.2 -4.5 13.7 50.4 88 92 A K E +FH 23 97C 46 -65,-2.3 -65,-2.4 -2,-0.4 2,-0.5 -0.897 3.6 178.1-142.1 105.3 -7.3 11.2 50.9 89 93 A L E -FH 22 96C 0 7,-1.8 7,-2.0 -2,-0.4 2,-0.4 -0.944 18.9-168.0-104.7 124.5 -9.8 10.6 48.1 90 94 A Q E +FH 21 95C 39 -69,-2.8 -70,-2.6 -2,-0.5 -69,-1.4 -0.954 15.2 179.1-128.5 126.7 -12.2 7.8 49.1 91 95 A T - 0 0 0 3,-3.6 -72,-0.1 -2,-0.4 -15,-0.0 -0.467 50.8 -86.7-106.3-178.1 -14.9 5.8 47.3 92 96 A A S S+ 0 0 75 -74,-0.4 -16,-0.1 -2,-0.2 -73,-0.0 0.948 123.2 10.8 -55.1 -52.1 -17.2 3.0 48.6 93 97 A D S S+ 0 0 70 -80,-0.1 -17,-3.0 -18,-0.1 2,-0.2 0.874 127.6 44.9 -94.8 -47.9 -14.6 0.2 48.0 94 98 A K E -G 75 0C 65 -19,-0.3 -3,-3.6 -81,-0.3 2,-0.3 -0.633 51.3-174.3-104.7 160.9 -11.3 1.9 47.3 95 99 A T E -GH 74 90C 5 -21,-1.5 -21,-2.9 -5,-0.3 2,-0.4 -0.968 11.8-154.2-147.6 128.5 -9.4 4.9 48.7 96 100 A I E -GH 73 89C 0 -7,-2.0 -7,-1.8 -2,-0.3 2,-0.4 -0.887 13.8-158.6-106.9 141.4 -6.2 6.3 47.2 97 101 A L E -GH 72 88C 9 -25,-2.7 -25,-1.3 -2,-0.4 2,-0.6 -0.974 11.1-150.9-126.5 135.8 -3.7 8.1 49.5 98 102 A L E -GH 71 87C 0 -11,-2.2 -12,-2.9 -2,-0.4 -11,-1.5 -0.904 21.8-171.7-106.9 116.7 -1.0 10.6 48.8 99 103 A Y E -GH 70 85C 28 -29,-2.1 -29,-1.8 -2,-0.6 -14,-0.2 -0.827 56.9 -4.5-109.9 145.7 1.8 10.5 51.2 100 104 A S S S+ 0 0 25 -16,-2.5 -31,-0.3 -2,-0.3 -32,-0.2 0.205 85.5 135.1 65.2 -12.9 4.8 12.8 51.7 101 105 A A + 0 0 2 -2,-0.2 -1,-0.2 -33,-0.2 -36,-0.1 -0.258 29.4 179.2 -69.3 156.4 4.2 15.1 48.7 102 106 A S + 0 0 83 -38,-0.6 2,-2.0 1,-0.1 -1,-0.1 0.610 65.2 82.1-121.4 -39.5 4.5 18.9 48.9 103 107 A D E +D 64 0A 64 -39,-0.8 -39,-2.6 2,-0.0 2,-0.4 -0.521 63.0 141.4 -73.7 82.8 3.7 20.0 45.4 104 108 A I E +D 63 0A 12 -2,-2.0 2,-0.3 -41,-0.2 -41,-0.2 -0.987 18.4 161.8-133.5 125.3 -0.1 19.9 45.7 105 109 A E E -D 62 0A 71 -43,-2.4 -43,-3.1 -2,-0.4 2,-0.6 -0.986 34.5-137.7-142.6 150.2 -2.5 22.3 44.1 106 110 A M E -D 61 0A 9 -2,-0.3 2,-0.4 -45,-0.2 -45,-0.2 -0.948 35.0-166.7-106.7 116.4 -6.2 22.5 43.2 107 111 A L E -D 60 0A 3 -47,-3.2 -47,-1.4 -2,-0.6 5,-0.0 -0.863 17.9-142.9-113.6 141.2 -6.5 24.2 39.7 108 112 A R > - 0 0 135 -2,-0.4 3,-2.0 -49,-0.2 4,-0.4 -0.634 40.2-102.3 -90.6 155.3 -9.4 25.7 37.8 109 113 A P G >> S+ 0 0 64 0, 0.0 3,-1.3 0, 0.0 4,-0.6 0.828 122.9 56.9 -44.7 -41.4 -9.4 25.1 34.0 110 114 A E G 34 S+ 0 0 106 1,-0.2 4,-0.4 2,-0.1 3,-0.2 0.789 102.9 54.9 -64.0 -28.3 -8.1 28.7 33.4 111 115 A Q G <> S+ 0 0 65 -3,-2.0 4,-0.6 1,-0.2 -1,-0.2 0.405 88.7 80.0 -87.7 2.1 -5.0 28.0 35.6 112 116 A L T X4 S+ 0 0 36 -3,-1.3 3,-0.6 -4,-0.4 -1,-0.2 0.944 94.5 41.9 -72.8 -50.4 -3.9 25.0 33.7 113 117 A T T 3< S+ 0 0 79 -4,-0.6 -1,-0.2 1,-0.2 -2,-0.1 0.710 116.4 49.8 -72.5 -19.1 -2.2 26.8 30.8 114 118 A T T 34 S+ 0 0 96 -4,-0.4 -1,-0.2 4,-0.0 -2,-0.2 0.547 79.6 115.1 -96.0 -8.4 -0.6 29.4 33.1 115 119 A H > S+ 0 0 61 1,-0.2 3,-2.5 2,-0.1 4,-0.8 0.970 115.1 57.7 -65.1 -53.5 5.5 23.4 35.4 118 122 A L T 34 S+ 0 0 1 1,-0.3 3,-0.5 2,-0.2 -1,-0.2 0.790 101.4 55.7 -49.3 -35.0 2.4 22.5 33.3 119 123 A Q T 3< S+ 0 0 85 -4,-2.3 -1,-0.3 1,-0.2 -2,-0.1 0.216 103.6 58.2 -86.0 19.7 3.4 25.0 30.5 120 124 A R T <4 S+ 0 0 44 -3,-2.5 2,-0.4 1,-0.3 -1,-0.2 0.596 110.4 37.1-115.1 -24.2 6.7 23.2 30.3 121 125 A V S < S- 0 0 8 -4,-0.8 36,-0.3 -3,-0.5 -1,-0.3 -0.935 70.3-156.9-138.5 115.3 5.4 19.7 29.5 122 126 A G - 0 0 1 34,-2.3 38,-0.3 -2,-0.4 -74,-0.3 -0.315 42.1 -69.0 -82.3 168.7 2.4 18.9 27.3 123 127 A P - 0 0 2 0, 0.0 37,-2.6 0, 0.0 2,-0.5 -0.057 56.8-104.0 -52.5 154.6 0.2 15.6 27.4 124 128 A D B > -i 160 0D 41 -78,-0.4 3,-2.5 35,-0.2 6,-0.2 -0.745 14.8-137.9 -91.5 129.5 1.9 12.4 26.2 125 129 A V T 3 S+ 0 0 1 35,-2.6 77,-0.1 -2,-0.5 -1,-0.1 0.720 106.2 55.8 -54.2 -22.9 0.9 11.1 22.8 126 130 A L T 3 S+ 0 0 58 34,-0.3 -1,-0.3 75,-0.1 3,-0.1 0.091 79.9 115.3 -97.4 22.7 0.8 7.6 24.2 127 131 A D X - 0 0 1 -3,-2.5 3,-1.9 1,-0.2 -82,-0.0 -0.838 59.3-152.0 -95.4 108.1 -1.7 8.7 26.8 128 132 A P T 3 S+ 0 0 88 0, 0.0 -1,-0.2 0, 0.0 -3,-0.0 0.849 94.7 55.0 -43.7 -45.2 -5.0 6.9 26.2 129 133 A N T 3 S+ 0 0 43 -85,-0.1 2,-0.7 -3,-0.1 -84,-0.1 0.719 85.1 94.1 -66.6 -22.9 -7.0 9.7 27.7 130 134 A L < - 0 0 6 -3,-1.9 -3,-0.1 -6,-0.2 3,-0.0 -0.630 65.6-166.1 -74.4 112.1 -5.5 12.3 25.4 131 135 A T >> - 0 0 57 -2,-0.7 4,-1.8 1,-0.1 3,-1.2 -0.660 33.4-114.6-104.4 157.8 -7.9 12.5 22.4 132 136 A P H 3> S+ 0 0 34 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.896 117.9 58.1 -50.4 -46.0 -7.6 14.1 18.9 133 137 A E H 3> S+ 0 0 62 1,-0.2 4,-1.4 2,-0.2 5,-0.1 0.837 107.8 48.0 -55.2 -33.4 -10.3 16.6 19.9 134 138 A V H <> S+ 0 0 54 -3,-1.2 4,-1.9 2,-0.2 -1,-0.2 0.841 109.2 51.9 -76.3 -35.6 -7.9 17.7 22.7 135 139 A V H X S+ 0 0 0 -4,-1.8 4,-3.2 2,-0.2 -2,-0.2 0.898 107.2 53.1 -67.7 -41.1 -4.9 17.9 20.4 136 140 A K H X S+ 0 0 18 -4,-2.7 4,-2.7 2,-0.2 -1,-0.2 0.932 107.8 51.2 -59.5 -46.1 -6.7 20.1 18.0 137 141 A E H X S+ 0 0 131 -4,-1.4 4,-1.3 2,-0.2 -1,-0.2 0.920 112.6 45.8 -55.0 -48.3 -7.6 22.5 20.8 138 142 A R H >< S+ 0 0 37 -4,-1.9 3,-0.6 2,-0.2 6,-0.4 0.929 110.7 53.6 -61.4 -47.5 -4.0 22.6 21.9 139 143 A L H 3< S+ 0 0 0 -4,-3.2 -2,-0.2 1,-0.2 -1,-0.2 0.898 115.2 41.0 -55.2 -41.5 -3.0 23.1 18.3 140 144 A L H 3< S+ 0 0 75 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.602 87.0 113.4 -85.6 -12.3 -5.4 26.1 18.0 141 145 A S S XX S- 0 0 35 -4,-1.3 4,-2.7 -3,-0.6 3,-1.6 -0.263 82.8-109.9 -58.7 149.9 -4.7 27.7 21.4 142 146 A P T 34 S+ 0 0 121 0, 0.0 4,-0.3 0, 0.0 -1,-0.1 0.705 115.1 66.7 -52.1 -24.6 -3.0 31.1 21.2 143 147 A R T 34 S+ 0 0 77 1,-0.1 -4,-0.1 -5,-0.1 -5,-0.1 0.834 121.4 8.7 -69.7 -34.1 0.2 29.5 22.5 144 148 A F T X4 S+ 0 0 2 -3,-1.6 3,-2.2 -6,-0.4 38,-0.4 0.718 96.3 95.4-119.3 -33.5 0.8 27.3 19.5 145 149 A R T 3< S+ 0 0 94 -4,-2.7 38,-1.3 -7,-0.3 39,-0.1 0.668 94.0 48.0 -36.7 -23.5 -1.5 28.2 16.6 146 150 A N T 3 S+ 0 0 80 -4,-0.3 2,-0.4 -5,-0.2 -1,-0.3 -0.102 89.0 105.2-115.3 37.1 1.3 30.4 15.3 147 151 A R S < S- 0 0 87 -3,-2.2 35,-0.4 4,-0.0 2,-0.1 -0.917 73.6-111.6-118.0 142.1 4.3 28.1 15.5 148 152 A Q >> - 0 0 104 -2,-0.4 4,-2.2 1,-0.2 3,-0.7 -0.481 23.0-134.1 -66.7 138.3 6.0 26.3 12.6 149 153 A F H 3> S+ 0 0 0 31,-1.8 4,-2.5 1,-0.2 30,-0.2 0.794 97.6 77.5 -64.6 -27.2 5.5 22.6 12.9 150 154 A A H 34 S+ 0 0 25 28,-2.2 -1,-0.2 1,-0.2 29,-0.1 0.899 113.9 17.4 -48.0 -49.1 9.2 22.0 12.2 151 155 A G H X> S+ 0 0 35 -3,-0.7 3,-1.9 27,-0.3 4,-0.7 0.795 119.2 65.8 -94.5 -34.2 10.0 23.0 15.8 152 156 A L H >< S+ 0 0 0 -4,-2.2 3,-1.6 1,-0.3 7,-0.3 0.921 100.6 51.2 -53.8 -49.0 6.6 22.6 17.4 153 157 A L T 3< S+ 0 0 1 -4,-2.5 -1,-0.3 1,-0.3 -2,-0.1 0.461 112.2 49.6 -70.4 2.2 6.6 18.8 16.8 154 158 A L T <4 S+ 0 0 42 -3,-1.9 2,-0.7 -5,-0.2 -1,-0.3 0.445 90.2 96.5-114.7 -6.5 10.0 18.8 18.4 155 159 A D XX - 0 0 40 -3,-1.6 3,-1.9 -4,-0.7 4,-1.3 -0.766 56.4-162.6 -93.5 108.7 8.9 20.9 21.5 156 160 A Q T 34 S+ 0 0 113 -2,-0.7 -34,-2.3 1,-0.3 -1,-0.1 0.673 86.9 71.6 -61.4 -18.5 8.0 18.7 24.5 157 161 A A T 34 S+ 0 0 10 -36,-0.3 -1,-0.3 1,-0.2 -36,-0.2 0.774 104.3 42.5 -68.0 -25.1 6.1 21.7 26.0 158 162 A F T <4 S- 0 0 0 -3,-1.9 2,-0.3 1,-0.3 -2,-0.2 0.930 135.2 -8.1 -84.2 -56.6 3.5 21.1 23.3 159 163 A L >< - 0 0 1 -4,-1.3 3,-0.6 -7,-0.3 -1,-0.3 -0.976 66.3-134.0-148.8 131.6 3.3 17.3 23.4 160 164 A A B 3 S+i 124 0D 15 -37,-2.6 -35,-2.6 -38,-0.3 -34,-0.3 -0.617 84.5 40.2 -86.8 144.9 5.4 14.7 25.2 161 165 A G T 3 S+ 0 0 45 -2,-0.3 2,-0.6 1,-0.2 -1,-0.2 0.513 78.6 130.3 99.4 7.9 6.7 11.6 23.4 162 166 A L < + 0 0 23 -3,-0.6 -1,-0.2 4,-0.0 2,-0.2 -0.850 27.9 174.5-104.7 114.0 7.6 13.2 20.1 163 167 A G >> - 0 0 14 -2,-0.6 4,-1.4 -3,-0.1 3,-1.1 -0.556 47.3-100.1-104.8 172.5 11.0 12.6 18.5 164 168 A N H 3> S+ 0 0 9 1,-0.2 4,-1.8 2,-0.2 5,-0.2 0.788 119.6 61.5 -63.8 -28.1 12.3 13.8 15.1 165 169 A Y H 3> S+ 0 0 92 1,-0.2 4,-0.6 2,-0.2 -1,-0.2 0.708 109.9 41.2 -71.3 -20.8 11.7 10.4 13.6 166 170 A L H <> S+ 0 0 4 -3,-1.1 4,-2.2 2,-0.1 -1,-0.2 0.679 108.1 62.2 -95.4 -25.7 8.0 10.8 14.3 167 171 A R H X S+ 0 0 12 -4,-1.4 4,-2.0 2,-0.2 -2,-0.2 0.956 106.6 43.0 -64.3 -51.8 7.9 14.4 13.3 168 172 A V H X S+ 0 0 0 -4,-1.8 4,-1.6 2,-0.2 -1,-0.2 0.888 115.4 48.6 -63.3 -40.9 8.9 13.7 9.7 169 173 A E H X S+ 0 0 9 -4,-0.6 4,-1.3 1,-0.2 -1,-0.2 0.924 110.6 51.8 -65.6 -44.8 6.6 10.7 9.3 170 174 A I H X S+ 0 0 0 -4,-2.2 4,-0.7 1,-0.2 3,-0.2 0.888 111.0 46.5 -57.1 -45.2 3.6 12.6 10.8 171 175 A L H <>S+ 0 0 0 -4,-2.0 5,-2.8 1,-0.2 3,-0.4 0.806 108.9 55.5 -71.1 -30.3 4.1 15.5 8.4 172 176 A W H <5S+ 0 0 26 -4,-1.6 3,-0.5 1,-0.2 -1,-0.2 0.755 101.4 58.4 -74.5 -24.4 4.5 13.2 5.4 173 177 A Q H <5S+ 0 0 91 -4,-1.3 -1,-0.2 -3,-0.2 -2,-0.2 0.733 113.4 36.6 -79.3 -19.9 1.2 11.6 6.1 174 178 A V T <5S- 0 0 28 -4,-0.7 -1,-0.2 -3,-0.4 -2,-0.2 0.189 114.0-115.3-113.6 14.5 -0.8 14.8 5.8 175 179 A G T 5 + 0 0 15 -3,-0.5 83,-1.4 1,-0.2 2,-0.4 0.832 64.1 143.7 57.3 43.0 1.3 16.2 3.0 176 180 A L < - 0 0 4 -5,-2.8 -1,-0.2 81,-0.2 2,-0.1 -0.900 44.4-139.2-120.7 144.1 2.8 19.1 4.9 177 181 A T > - 0 0 19 81,-0.4 3,-1.0 -2,-0.4 -28,-0.2 -0.457 37.6-104.8 -83.5 165.1 6.2 20.9 4.9 178 182 A G T 3 S+ 0 0 10 1,-0.2 -28,-2.2 -2,-0.1 -27,-0.3 0.408 108.0 75.1 -75.8 4.9 7.7 22.0 8.2 179 183 A N T 3 S+ 0 0 95 -31,-0.2 -1,-0.2 -30,-0.2 2,-0.1 0.334 72.9 108.3 -98.4 7.2 6.9 25.7 7.6 180 184 A H < - 0 0 37 -3,-1.0 -31,-1.8 2,-0.0 2,-0.3 -0.471 53.5-148.8 -86.1 155.9 3.1 25.5 8.3 181 185 A K > - 0 0 37 -33,-0.2 3,-2.3 -2,-0.1 -35,-0.1 -0.865 29.7-116.1-119.4 154.2 1.2 26.8 11.3 182 186 A A G > S+ 0 0 2 -35,-0.4 3,-0.6 -38,-0.4 -36,-0.2 0.695 117.9 62.2 -63.0 -12.8 -2.0 25.4 12.8 183 187 A K G 3 S+ 0 0 104 -38,-1.3 -1,-0.3 1,-0.2 -37,-0.1 0.493 92.8 60.1 -91.2 -4.1 -3.4 28.8 11.7 184 188 A D G < S+ 0 0 84 -3,-2.3 2,-0.4 -39,-0.1 -1,-0.2 -0.075 90.5 100.0-109.2 31.0 -2.8 28.1 8.0 185 189 A L < - 0 0 24 -3,-0.6 -3,-0.0 -5,-0.0 0, 0.0 -0.967 66.3-134.5-127.8 133.4 -5.0 25.1 8.0 186 190 A N > - 0 0 83 -2,-0.4 4,-2.5 1,-0.1 5,-0.2 -0.179 44.9 -93.9 -68.8 170.4 -8.6 24.4 6.9 187 191 A A H > S+ 0 0 88 1,-0.2 4,-2.2 2,-0.2 5,-0.2 0.912 126.1 47.7 -54.4 -46.5 -10.8 22.4 9.3 188 192 A A H > S+ 0 0 71 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.903 111.5 49.0 -62.5 -45.6 -10.0 19.1 7.5 189 193 A Q H > S+ 0 0 64 1,-0.2 4,-1.8 2,-0.2 5,-0.2 0.906 110.9 51.4 -61.1 -42.4 -6.2 19.7 7.4 190 194 A L H X S+ 0 0 16 -4,-2.5 4,-1.9 1,-0.2 -2,-0.2 0.920 112.3 45.6 -62.4 -43.7 -6.2 20.5 11.1 191 195 A D H X S+ 0 0 77 -4,-2.2 4,-1.4 -5,-0.2 -1,-0.2 0.850 107.0 58.2 -70.0 -33.1 -8.1 17.4 12.0 192 196 A A H X S+ 0 0 38 -4,-2.3 4,-1.6 1,-0.2 3,-0.3 0.929 111.7 41.0 -60.8 -47.3 -5.9 15.1 9.8 193 197 A L H X S+ 0 0 0 -4,-1.8 4,-2.7 1,-0.2 -1,-0.2 0.873 107.6 62.3 -67.9 -39.4 -2.7 16.2 11.6 194 198 A A H < S+ 0 0 0 -4,-1.9 -1,-0.2 1,-0.2 4,-0.2 0.833 111.0 39.9 -56.8 -32.3 -4.6 16.0 15.0 195 199 A H H >X S+ 0 0 59 -4,-1.4 4,-2.6 -3,-0.3 3,-0.8 0.800 111.0 58.6 -85.3 -31.7 -5.1 12.3 14.4 196 200 A A H 3X S+ 0 0 0 -4,-1.6 4,-2.0 1,-0.2 -2,-0.2 0.953 95.8 62.0 -60.7 -51.5 -1.6 11.8 12.9 197 201 A L H 3< S+ 0 0 0 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.1 0.670 117.3 29.8 -50.0 -22.1 0.2 13.1 16.0 198 202 A L H <> S+ 0 0 3 -3,-0.8 4,-2.6 -4,-0.2 5,-0.3 0.798 116.4 55.1-105.7 -43.7 -1.4 10.2 18.0 199 203 A E H X S+ 0 0 104 -4,-2.6 4,-2.2 1,-0.2 5,-0.2 0.902 111.3 40.0 -60.7 -49.6 -1.8 7.4 15.4 200 204 A I H X S+ 0 0 15 -4,-2.0 4,-2.7 2,-0.2 -1,-0.2 0.855 117.0 49.8 -74.5 -31.2 1.8 7.1 14.1 201 205 A P H > S+ 0 0 4 0, 0.0 4,-1.9 0, 0.0 -2,-0.2 0.941 118.0 39.5 -69.5 -41.8 3.3 7.5 17.6 202 206 A R H X S+ 0 0 80 -4,-2.6 4,-2.7 2,-0.2 -2,-0.2 0.824 117.7 50.2 -72.1 -33.5 1.1 4.8 19.1 203 207 A F H X S+ 0 0 85 -4,-2.2 4,-1.3 -5,-0.3 -3,-0.2 0.922 109.4 51.0 -69.6 -46.8 1.4 2.7 15.9 204 208 A S H < S+ 0 0 16 -4,-2.7 -2,-0.2 -5,-0.2 -1,-0.2 0.919 119.0 36.6 -56.2 -47.4 5.2 3.0 16.0 205 209 A Y H >< S+ 0 0 124 -4,-1.9 3,-2.0 1,-0.2 -2,-0.2 0.925 108.6 60.4 -72.9 -51.0 5.3 2.0 19.7 206 210 A A H 3< S+ 0 0 80 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.777 116.2 36.5 -50.8 -27.4 2.6 -0.7 19.8 207 211 A T T 3< S+ 0 0 45 -4,-1.3 13,-0.3 -5,-0.2 -1,-0.3 0.280 80.8 135.7-112.9 12.5 4.5 -2.6 17.2 208 212 A R < - 0 0 190 -3,-2.0 2,-0.3 11,-0.1 -3,-0.1 -0.324 41.8-148.6 -61.0 142.2 8.2 -2.0 18.2 209 213 A G - 0 0 22 1,-0.2 3,-0.1 0, 0.0 5,-0.1 -0.793 22.8 -86.5-113.7 158.6 10.2 -5.2 18.1 210 214 A Q > - 0 0 138 -2,-0.3 3,-0.9 1,-0.1 4,-0.3 0.129 63.1 -73.8 -49.8 173.6 13.1 -6.5 20.1 211 215 A V T 3 S+ 0 0 115 1,-0.2 -1,-0.1 2,-0.1 0, 0.0 -0.523 113.5 10.2 -80.6 142.7 16.7 -5.5 19.1 212 216 A D T > S+ 0 0 99 -2,-0.2 3,-1.0 -3,-0.1 -1,-0.2 0.542 90.6 119.5 70.5 6.2 18.4 -7.0 16.0 213 217 A E G X> + 0 0 39 -3,-0.9 3,-2.2 1,-0.2 4,-0.7 0.827 60.2 70.1 -69.1 -31.1 15.0 -8.6 15.2 214 218 A N G 34 S+ 0 0 117 -4,-0.3 -1,-0.2 1,-0.3 3,-0.1 0.703 78.5 79.9 -60.0 -18.0 15.1 -6.7 11.9 215 219 A K G <4 S+ 0 0 156 -3,-1.0 -1,-0.3 1,-0.2 -2,-0.2 0.754 114.9 14.2 -61.4 -22.5 17.9 -9.0 10.8 216 220 A H T <4 S+ 0 0 153 -3,-2.2 2,-0.2 1,-0.3 -1,-0.2 0.301 132.3 33.8-136.3 9.1 15.2 -11.6 10.0 217 221 A H < - 0 0 103 -4,-0.7 -1,-0.3 -3,-0.1 2,-0.3 -0.767 68.4-130.6-170.8 121.5 11.9 -9.7 10.0 218 222 A G - 0 0 37 -2,-0.2 4,-0.1 -3,-0.1 -4,-0.0 -0.541 34.7-109.8 -77.3 134.7 10.8 -6.2 9.0 219 223 A A - 0 0 41 -2,-0.3 -1,-0.1 2,-0.2 -11,-0.1 -0.169 19.7-124.4 -57.9 154.2 8.7 -4.3 11.4 220 224 A L S S+ 0 0 136 -13,-0.3 2,-0.6 1,-0.1 -1,-0.1 0.864 99.6 71.0 -69.2 -36.4 5.1 -3.8 10.4 221 225 A F S S- 0 0 22 -14,-0.2 2,-0.4 -17,-0.1 -2,-0.2 -0.740 72.0-171.4 -84.5 117.0 5.6 -0.0 10.8 222 226 A R - 0 0 154 -2,-0.6 2,-0.1 -4,-0.1 -2,-0.0 -0.913 21.7-123.9-113.7 137.9 7.8 1.3 8.0 223 227 A F - 0 0 72 -2,-0.4 -57,-0.1 1,-0.1 -58,-0.0 -0.491 16.6-165.3 -73.3 148.6 9.3 4.8 7.8 224 228 A K S S+ 0 0 55 -2,-0.1 10,-0.2 9,-0.0 -1,-0.1 0.670 83.0 0.7-107.7 -26.5 8.4 6.7 4.6 225 229 A V S > S+ 0 0 0 -60,-0.2 3,-1.4 26,-0.1 2,-0.5 0.478 96.8 107.0-139.0 -13.4 10.9 9.6 4.8 226 230 A F T 3 S- 0 0 36 1,-0.3 -3,-0.1 -61,-0.2 -61,-0.1 -0.630 106.7 -8.1 -74.6 121.1 13.0 9.1 7.9 227 231 A H T 3 S+ 0 0 128 -2,-0.5 -1,-0.3 1,-0.1 15,-0.1 0.830 109.6 109.3 61.5 32.5 16.5 8.0 6.7 228 232 A R X + 0 0 72 -3,-1.4 3,-1.1 13,-0.1 2,-0.6 -0.145 34.8 145.1-128.3 36.4 15.1 7.6 3.2 229 233 A D T 3 S+ 0 0 77 1,-0.2 12,-0.2 10,-0.1 10,-0.1 -0.682 72.0 23.9 -80.3 118.9 16.8 10.5 1.5 230 234 A G T 3 S+ 0 0 51 10,-1.5 -1,-0.2 -2,-0.6 11,-0.1 0.160 103.0 100.1 113.2 -16.7 17.7 9.5 -2.1 231 235 A E S < S- 0 0 30 -3,-1.1 9,-2.3 9,-0.2 -1,-0.6 -0.587 79.9 -95.5 -96.4 161.2 15.0 6.9 -2.3 232 236 A P B -J 239 0E 73 0, 0.0 2,-0.7 0, 0.0 7,-0.2 -0.340 34.9-108.7 -76.6 161.4 11.6 7.4 -4.1 233 237 A C > - 0 0 4 5,-0.7 4,-1.8 1,-0.1 5,-0.2 -0.807 17.2-138.0 -93.5 112.8 8.4 8.4 -2.3 234 238 A E T 4 S+ 0 0 140 -2,-0.7 -1,-0.1 -10,-0.2 -10,-0.0 0.667 102.3 49.2 -38.8 -21.0 5.9 5.5 -2.1 235 239 A R T 4 S- 0 0 164 3,-0.1 -1,-0.2 0, 0.0 0, 0.0 0.953 134.2 -4.7 -86.9 -70.8 3.3 8.2 -3.0 236 240 A C T 4 S- 0 0 67 2,-0.1 -2,-0.2 17,-0.0 0, 0.0 0.640 88.4-117.9-103.3 -20.9 4.5 10.3 -5.9 237 241 A G < + 0 0 40 -4,-1.8 -3,-0.1 1,-0.3 3,-0.0 0.440 59.6 146.8 97.9 -0.7 8.0 8.9 -6.6 238 242 A S - 0 0 38 -5,-0.2 -5,-0.7 -6,-0.2 2,-0.6 -0.331 60.0 -98.6 -68.7 151.2 10.0 12.1 -6.0 239 243 A I B -J 232 0E 90 -7,-0.2 2,-0.2 1,-0.1 -1,-0.1 -0.634 41.0-123.4 -76.5 119.4 13.4 11.7 -4.5 240 244 A I - 0 0 2 -9,-2.3 -10,-1.5 -2,-0.6 13,-0.2 -0.416 32.1-164.7 -64.3 128.6 13.1 12.3 -0.7 241 245 A E E -K 252 0F 101 11,-1.8 11,-1.6 -12,-0.2 2,-0.3 -0.448 5.5-156.6-107.2-178.0 15.4 15.1 0.4 242 246 A K E -K 251 0F 75 9,-0.2 9,-0.2 -2,-0.2 2,-0.1 -0.928 17.8-114.6-164.3 139.4 16.6 16.3 3.9 243 247 A T - 0 0 54 7,-0.7 7,-0.2 -2,-0.3 3,-0.1 -0.372 21.3-177.1 -75.9 151.6 17.9 19.4 5.5 244 248 A T + 0 0 110 1,-0.1 2,-1.3 5,-0.1 -1,-0.1 0.750 67.0 79.5 -85.8 -79.1 21.5 19.8 6.9 245 249 A L S S+ 0 0 87 3,-0.1 2,-0.5 4,-0.0 -1,-0.1 -0.727 90.6 154.0 -36.6 88.6 21.7 23.0 8.3 246 250 A S S S- 0 0 53 -2,-1.3 -2,-0.0 1,-0.2 0, 0.0 -0.913 75.5-162.7-170.7 149.7 20.0 21.8 11.3 247 251 A S S S- 0 0 120 -2,-0.5 -1,-0.2 1,-0.4 -96,-0.0 0.977 109.4 -4.9 -69.6 -81.1 18.7 21.1 14.6 248 252 A R S S- 0 0 116 -3,-0.1 -1,-0.4 -84,-0.0 -5,-0.1 -0.993 96.6 -96.9-109.6 119.8 17.4 17.6 13.9 249 253 A P - 0 0 45 0, 0.0 2,-0.2 0, 0.0 -5,-0.1 -0.085 42.4-143.6 -40.9 114.8 17.8 16.4 10.3 250 254 A F - 0 0 18 -7,-0.2 -7,-0.7 -24,-0.1 2,-0.4 -0.530 14.4-162.4 -82.8 153.8 14.4 17.1 8.6 251 255 A Y E +K 242 0F 13 -9,-0.2 2,-0.3 -2,-0.2 -9,-0.2 -1.000 21.5 139.5-139.4 136.6 13.1 14.6 6.0 252 256 A W E -K 241 0F 45 -11,-1.6 -11,-1.8 -2,-0.4 -75,-0.1 -0.983 50.9-104.0-165.2 170.5 10.4 15.1 3.4 253 257 A C > - 0 0 0 -2,-0.3 4,-1.8 -13,-0.2 3,-0.2 -0.905 19.7-160.2-108.0 105.7 9.2 14.5 -0.1 254 258 A P T 4 S+ 0 0 57 0, 0.0 -1,-0.1 0, 0.0 -14,-0.1 0.663 88.9 64.8 -58.0 -11.2 9.6 17.8 -2.1 255 259 A G T 4 S+ 0 0 42 1,-0.1 -16,-0.0 -16,-0.1 -15,-0.0 0.969 118.1 9.8 -77.8 -58.8 7.1 16.1 -4.5 256 260 A C T 4 S+ 0 0 21 -3,-0.2 2,-0.5 -18,-0.1 -1,-0.1 0.335 111.5 82.0-109.6 8.8 3.9 15.7 -2.5 257 261 A Q < 0 0 5 -4,-1.8 -81,-0.2 -81,-0.1 -82,-0.1 -0.958 360.0 360.0-113.9 127.4 4.6 17.8 0.6 258 262 A H 0 0 154 -83,-1.4 -81,-0.4 -2,-0.5 -3,-0.0 -0.995 360.0 360.0-156.7 360.0 4.2 21.6 0.4