==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-JAN-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER ISOMERASE 18-JAN-11 3QDF . COMPND 2 MOLECULE: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM MARINUM; . AUTHOR SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE (S . 252 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10920.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 173 68.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 11 4.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 81 32.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 27 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 18 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 3 2 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A S 0 0 128 0, 0.0 2,-0.3 0, 0.0 166,-0.0 0.000 360.0 360.0 360.0 71.3 -5.8 12.3 48.0 2 1 A M - 0 0 29 17,-0.0 166,-2.5 164,-0.0 2,-0.7 -0.876 360.0-117.7-145.0 165.5 -1.9 12.6 47.9 3 2 A R E -A 167 0A 48 -2,-0.3 15,-2.9 15,-0.2 2,-0.6 -0.956 36.3-159.5-105.3 108.7 1.6 11.2 47.7 4 3 A L E +AB 166 17A 1 162,-3.2 162,-3.1 -2,-0.7 2,-0.2 -0.817 23.8 154.1 -92.2 122.4 3.3 12.3 50.9 5 4 A G E - B 0 16A 0 11,-2.6 11,-2.4 -2,-0.6 2,-0.4 -0.767 38.3-118.3-132.7-179.9 7.1 12.3 50.7 6 5 A R E -CB 56 15A 31 50,-0.5 50,-3.1 9,-0.3 2,-0.3 -0.976 30.9-172.8-124.5 142.2 10.1 14.0 52.3 7 6 A I E -CB 55 14A 0 7,-2.9 7,-2.4 -2,-0.4 2,-0.6 -0.950 28.1-142.9-136.4 148.5 12.7 16.0 50.3 8 7 A A E +CB 54 13A 17 46,-2.3 46,-2.8 -2,-0.3 5,-0.2 -0.982 42.2 162.5-106.2 113.3 16.0 17.7 50.6 9 8 A S E > - B 0 12A 19 3,-3.4 3,-1.1 -2,-0.6 44,-0.1 -0.443 57.7 -82.3-114.3-174.3 15.7 20.8 48.5 10 9 A P T 3 S+ 0 0 98 0, 0.0 3,-0.1 0, 0.0 43,-0.0 0.933 131.7 49.5 -55.7 -46.9 17.6 24.1 48.2 11 10 A D T 3 S- 0 0 95 1,-0.2 2,-0.2 -3,-0.0 -3,-0.0 0.198 121.6-107.1 -81.5 16.1 15.6 25.5 51.2 12 11 A G E < -B 9 0A 30 -3,-1.1 -3,-3.4 2,-0.0 2,-0.5 -0.652 60.2 -13.7 107.1-154.3 16.3 22.3 53.3 13 12 A V E +B 8 0A 95 -5,-0.2 2,-0.3 -2,-0.2 -5,-0.2 -0.828 69.0 148.8 -99.1 126.0 14.4 19.2 54.5 14 13 A A E -B 7 0A 17 -7,-2.4 -7,-2.9 -2,-0.5 2,-0.1 -0.989 48.4-103.3-150.7 156.5 10.6 19.2 54.2 15 14 A F E -B 6 0A 45 18,-0.3 18,-2.7 -2,-0.3 2,-0.3 -0.492 46.4-171.9 -68.8 153.7 7.5 17.1 53.7 16 15 A A E -BD 5 32A 0 -11,-2.4 -11,-2.6 16,-0.3 2,-0.7 -0.996 32.0-123.9-150.2 147.0 6.1 17.5 50.2 17 16 A S E -BD 4 31A 7 14,-2.9 14,-3.2 -2,-0.3 2,-0.8 -0.867 31.4-147.8 -86.4 120.1 3.1 16.5 48.1 18 17 A I E - D 0 30A 2 -15,-2.9 2,-0.3 -2,-0.7 -15,-0.2 -0.811 23.0-171.3 -96.6 107.9 4.6 14.7 45.1 19 18 A E E + D 0 29A 67 10,-3.2 10,-2.3 -2,-0.8 2,-0.2 -0.696 28.0 53.6-108.4 149.4 2.4 15.4 42.2 20 19 A G S S- 0 0 42 -2,-0.3 2,-0.2 8,-0.2 8,-0.1 -0.557 85.7 -30.5 126.0 174.1 2.2 14.0 38.6 21 20 A E > - 0 0 144 -2,-0.2 3,-1.9 1,-0.1 6,-0.1 -0.461 50.3-134.8 -64.8 128.5 1.9 10.9 36.5 22 21 A L T 3 S+ 0 0 71 1,-0.3 -1,-0.1 -2,-0.2 6,-0.1 0.783 101.4 61.5 -53.1 -33.0 3.5 7.9 38.2 23 22 A D T 3 S+ 0 0 125 1,-0.2 -1,-0.3 2,-0.1 3,-0.1 0.354 103.3 51.3 -84.8 7.0 5.2 6.8 35.0 24 23 A N X + 0 0 87 -3,-1.9 3,-0.6 1,-0.1 4,-0.3 -0.471 59.3 162.7-134.8 67.3 7.2 10.0 34.8 25 24 A P G > S+ 0 0 68 0, 0.0 3,-1.3 0, 0.0 25,-0.2 0.836 73.0 62.1 -58.0 -32.5 8.9 10.5 38.2 26 25 A G G 3 S+ 0 0 39 1,-0.3 25,-1.4 24,-0.1 24,-0.2 0.905 106.0 43.7 -55.4 -48.4 11.4 13.0 36.7 27 26 A A G < S+ 0 0 68 -3,-0.6 -1,-0.3 23,-0.1 -6,-0.1 0.275 88.7 120.0 -84.5 9.0 8.7 15.5 35.7 28 27 A M < - 0 0 0 -3,-1.3 22,-3.3 -4,-0.3 2,-0.5 -0.403 62.4-127.1 -71.4 151.4 6.8 15.1 39.0 29 28 A T E -DE 19 49A 45 -10,-2.3 -10,-3.2 20,-0.3 2,-0.9 -0.912 7.3-148.6-105.5 127.2 6.4 18.3 41.1 30 29 A A E -DE 18 48A 0 18,-3.5 18,-1.5 -2,-0.5 2,-0.8 -0.855 15.8-161.8 -91.1 101.8 7.5 18.3 44.8 31 30 A R E -DE 17 47A 86 -14,-3.2 -14,-2.9 -2,-0.9 16,-0.2 -0.773 21.7-124.6 -91.0 106.6 5.0 20.7 46.4 32 31 A E E -D 16 0A 11 14,-1.9 12,-1.8 -2,-0.8 13,-0.6 -0.238 18.4-142.9 -59.1 128.2 6.5 21.8 49.7 33 32 A I E - E 0 43A 9 -18,-2.7 -18,-0.3 10,-0.2 10,-0.3 -0.748 15.4-174.2 -91.0 137.1 4.3 21.3 52.8 34 33 A A E - 0 0 51 8,-2.5 2,-0.3 -2,-0.4 9,-0.2 0.889 62.5 -1.2 -91.7 -63.6 4.4 23.9 55.6 35 34 A E E S+ E 0 42A 114 7,-0.5 7,-1.8 1,-0.2 -1,-0.3 -0.847 107.9 26.4-132.2 164.2 2.3 22.4 58.4 36 35 A H > + 0 0 101 -2,-0.3 3,-1.2 5,-0.2 -1,-0.2 0.878 47.7 172.0 59.2 52.6 0.2 19.4 59.4 37 36 A P T 3 S+ 0 0 27 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.815 84.0 42.2 -62.9 -24.9 1.6 16.5 57.3 38 37 A F T 3 S+ 0 0 71 2,-0.1 -2,-0.1 175,-0.0 176,-0.1 0.480 124.3 34.0 -95.6 -5.7 -0.6 14.0 59.2 39 38 A G S < S- 0 0 53 -3,-1.2 -3,-0.0 -4,-0.0 76,-0.0 0.287 129.5 -31.0-111.7-121.0 -3.7 16.2 59.2 40 39 A T S S- 0 0 125 -2,-0.0 -2,-0.1 0, 0.0 -5,-0.1 -0.892 74.3-141.0-102.7 102.3 -4.8 18.6 56.5 41 40 A P - 0 0 30 0, 0.0 2,-0.3 0, 0.0 -5,-0.2 -0.347 14.4-160.7 -67.9 143.7 -1.5 19.7 55.1 42 41 A N E -E 35 0A 62 -7,-1.8 -8,-2.5 2,-0.0 -7,-0.5 -0.806 16.6-124.8-113.2 167.1 -1.0 23.3 54.0 43 42 A F E -E 33 0A 94 -10,-0.3 -10,-0.2 -2,-0.3 -11,-0.1 -0.792 8.7-140.8-122.5 150.7 1.7 24.4 51.6 44 43 A T E - 0 0 57 -12,-1.8 -11,-0.1 -2,-0.3 3,-0.1 0.737 49.8-112.3 -77.8 -24.4 4.5 27.0 51.7 45 44 A G E S+ 0 0 69 -13,-0.6 2,-0.3 1,-0.4 -12,-0.1 0.104 82.2 114.9 105.9 -19.0 4.1 28.0 48.1 46 45 A R E + 0 0 121 -14,-0.2 -14,-1.9 -15,-0.0 -1,-0.4 -0.620 35.8 166.1 -85.7 144.5 7.4 26.5 47.0 47 46 A S E -E 31 0A 53 -2,-0.3 -16,-0.2 -16,-0.2 -18,-0.0 -0.984 12.2-169.9-149.1 158.5 7.7 23.6 44.6 48 47 A W E -E 30 0A 37 -18,-1.5 -18,-3.5 -2,-0.3 2,-0.1 -0.976 38.3 -96.2-138.4 150.1 10.4 22.0 42.5 49 48 A P E > -E 29 0A 65 0, 0.0 3,-1.6 0, 0.0 4,-0.3 -0.465 41.8-122.0 -57.8 141.9 10.6 19.4 39.8 50 49 A L G > S+ 0 0 14 -22,-3.3 3,-1.9 1,-0.3 -23,-0.1 0.855 110.7 65.5 -59.9 -34.6 11.3 16.2 41.7 51 50 A A G 3 S+ 0 0 78 -25,-1.4 -1,-0.3 -23,-0.3 -24,-0.1 0.720 97.7 57.7 -56.3 -23.6 14.5 15.7 39.5 52 51 A D G < S+ 0 0 108 -3,-1.6 -1,-0.3 -26,-0.2 2,-0.3 0.491 105.6 53.1 -88.3 -8.3 15.9 18.8 41.2 53 52 A V S < S- 0 0 20 -3,-1.9 2,-0.6 -4,-0.3 -44,-0.2 -0.829 85.1-106.1-126.4 164.2 15.6 17.6 44.8 54 53 A R E -C 8 0A 164 -46,-2.8 -46,-2.3 -2,-0.3 2,-0.5 -0.835 30.1-141.8 -92.7 119.6 16.7 14.5 46.9 55 54 A L E -C 7 0A 28 -2,-0.6 -48,-0.2 -48,-0.2 2,-0.1 -0.707 26.2-170.9 -79.9 124.7 13.8 12.2 47.7 56 55 A L E -C 6 0A 26 -50,-3.1 -50,-0.5 -2,-0.5 32,-0.1 -0.429 40.7 -61.8-108.2 177.8 14.2 10.8 51.3 57 56 A A - 0 0 12 32,-0.2 -1,-0.2 1,-0.1 106,-0.2 -0.450 55.6-128.0 -57.0 135.7 12.5 8.1 53.4 58 57 A P S S+ 0 0 0 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.564 80.9 30.5 -76.9 -5.6 8.9 9.5 53.5 59 58 A I - 0 0 2 103,-0.1 2,-0.8 -53,-0.1 -53,-0.1 -0.993 62.8-135.9-150.2 151.4 8.6 9.3 57.3 60 59 A L - 0 0 130 -2,-0.3 2,-0.2 155,-0.0 155,-0.1 -0.832 39.7-164.3-103.4 86.6 10.6 9.5 60.5 61 60 A A - 0 0 2 -2,-0.8 154,-0.2 1,-0.1 3,-0.1 -0.533 24.9-150.2 -78.7 141.1 9.1 6.6 62.3 62 61 A S S S- 0 0 59 1,-0.3 22,-0.4 -2,-0.2 2,-0.3 0.814 85.3 -3.0 -73.0 -29.5 9.5 6.1 66.1 63 62 A K - 0 0 41 149,-0.1 153,-1.9 20,-0.1 2,-0.5 -0.986 60.6-135.8-156.9 158.6 9.3 2.4 65.5 64 63 A V E -Fg 82 216A 0 18,-1.5 18,-2.3 -2,-0.3 2,-0.4 -0.971 21.8-166.1-119.2 111.5 8.8 -0.2 62.7 65 64 A V E -Fg 81 217A 0 151,-2.9 153,-2.4 -2,-0.5 2,-0.3 -0.828 13.4-166.6-101.7 138.6 6.4 -3.0 63.7 66 65 A C E -Fg 80 218A 0 14,-2.8 14,-1.8 -2,-0.4 2,-0.4 -0.937 17.7-136.5-133.0 152.6 6.4 -6.0 61.4 67 66 A V E -F 79 0A 2 151,-2.6 12,-0.2 -2,-0.3 3,-0.2 -0.860 16.3-151.8-109.2 133.9 4.4 -9.1 60.7 68 67 A G S S+ 0 0 12 10,-3.0 2,-0.4 -2,-0.4 153,-0.2 0.532 71.1 8.0 -67.9-139.5 5.9 -12.5 60.1 69 68 A K S S+ 0 0 96 1,-0.2 -1,-0.2 151,-0.1 9,-0.2 -0.297 73.9 146.7 -44.6 101.9 4.3 -15.2 58.0 70 69 A N + 0 0 1 151,-0.4 125,-2.3 -2,-0.4 2,-0.4 0.229 34.7 90.1-133.3 15.7 1.4 -13.4 56.3 71 70 A Y B K 194 0B 29 150,-0.3 123,-0.2 123,-0.3 150,-0.1 -0.953 360.0 360.0-120.1 142.4 0.8 -14.8 52.8 72 71 A T 0 0 115 121,-2.5 -1,-0.2 -2,-0.4 122,-0.1 0.944 360.0 360.0 -64.9 360.0 -1.5 -17.8 51.8 73 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 74 85 A P 0 0 154 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 130.4 -5.4 -19.2 60.7 75 86 A A - 0 0 83 1,-0.1 3,-0.1 3,-0.0 0, 0.0 -0.185 360.0 -94.8 -53.7 149.9 -2.6 -18.7 63.3 76 87 A D - 0 0 112 1,-0.1 -1,-0.1 128,-0.0 120,-0.0 -0.345 54.6 -84.6 -59.7 148.2 -2.5 -15.4 65.3 77 88 A P - 0 0 14 0, 0.0 2,-0.6 0, 0.0 -1,-0.1 -0.262 35.8-143.0 -57.7 141.9 -0.1 -12.7 63.8 78 89 A V - 0 0 86 -9,-0.2 -10,-3.0 -3,-0.1 2,-0.3 -0.958 25.1-168.4-105.5 119.6 3.5 -13.0 64.8 79 90 A I E +F 67 0A 46 -2,-0.6 2,-0.3 -12,-0.2 -12,-0.2 -0.762 14.2 167.3-111.9 157.1 5.0 -9.5 65.3 80 91 A F E -F 66 0A 21 -14,-1.8 -14,-2.8 -2,-0.3 2,-0.4 -0.920 26.4-114.2-153.6 173.7 8.5 -8.2 65.8 81 92 A L E -F 65 0A 77 -2,-0.3 -16,-0.2 -16,-0.2 73,-0.1 -0.910 10.1-162.1-120.5 145.0 10.3 -4.8 65.7 82 93 A K E -F 64 0A 3 -18,-2.3 -18,-1.5 -2,-0.4 2,-0.1 -0.969 33.6-116.5-113.2 140.9 12.9 -3.2 63.5 83 94 A P > - 0 0 52 0, 0.0 3,-2.4 0, 0.0 4,-0.3 -0.457 20.1-121.2 -74.3 147.1 14.7 -0.2 65.0 84 95 A N G > S+ 0 0 79 -22,-0.4 3,-1.3 1,-0.3 -23,-0.1 0.711 109.7 74.7 -64.5 -16.0 14.2 3.1 63.2 85 96 A T G 3 S+ 0 0 90 1,-0.2 73,-0.6 70,-0.1 -1,-0.3 0.619 87.1 64.7 -66.2 -10.1 18.0 3.2 62.8 86 97 A A G < S+ 0 0 0 -3,-2.4 74,-2.7 71,-0.2 -1,-0.2 0.662 80.7 106.9 -83.7 -14.7 17.4 0.5 60.1 87 98 A I E < +l 160 0C 30 -3,-1.3 2,-0.3 -4,-0.3 71,-0.2 -0.366 39.1 167.2 -72.9 134.3 15.4 2.9 57.9 88 99 A V E -l 161 0C 19 72,-1.3 74,-2.3 70,-0.2 3,-0.1 -0.963 26.9-124.6-132.6 161.3 16.8 4.2 54.6 89 100 A G > - 0 0 6 -2,-0.3 3,-1.4 72,-0.2 74,-0.2 -0.138 50.3 -50.3 -87.9-174.9 15.0 6.0 51.8 90 101 A P T 3 S+ 0 0 9 0, 0.0 -1,-0.2 0, 0.0 156,-0.2 -0.295 122.2 11.2 -55.4 140.1 14.8 5.3 48.1 91 102 A N T 3 S+ 0 0 110 154,-3.3 155,-0.2 1,-0.2 -35,-0.0 0.442 90.8 130.3 71.1 5.5 18.1 4.8 46.3 92 103 A V < - 0 0 60 -3,-1.4 -1,-0.2 153,-0.2 -4,-0.1 -0.752 65.0-105.0 -89.8 135.0 20.2 4.5 49.5 93 104 A P - 0 0 31 0, 0.0 2,-0.5 0, 0.0 155,-0.2 -0.291 18.1-135.8 -62.0 139.7 22.5 1.4 49.6 94 105 A I E -m 248 0D 0 153,-2.5 155,-2.7 65,-0.1 2,-0.6 -0.859 25.4-148.9 -83.6 126.5 21.6 -1.6 51.7 95 106 A R E -m 249 0D 114 -2,-0.5 155,-0.2 62,-0.4 64,-0.1 -0.928 4.6-150.3-109.1 113.4 24.9 -2.5 53.4 96 107 A L E -m 250 0D 0 153,-2.7 155,-2.8 -2,-0.6 62,-0.0 -0.678 24.3-112.3 -79.8 130.7 25.4 -6.2 54.1 97 108 A P > - 0 0 14 0, 0.0 3,-1.6 0, 0.0 -1,-0.1 -0.386 26.6-120.0 -57.6 141.0 27.6 -7.0 57.1 98 109 A A T 3 S+ 0 0 70 1,-0.2 -2,-0.0 152,-0.1 152,-0.0 0.905 112.8 46.7 -49.8 -40.9 30.8 -8.7 55.8 99 110 A N T 3 S+ 0 0 126 2,-0.0 2,-0.5 0, 0.0 -1,-0.2 0.465 89.5 100.8 -84.4 -3.0 29.9 -11.7 57.9 100 111 A A < - 0 0 0 -3,-1.6 3,-0.3 42,-0.0 41,-0.0 -0.740 49.6-169.5 -98.1 123.7 26.2 -12.2 57.0 101 112 A S + 0 0 67 -2,-0.5 39,-0.1 1,-0.3 128,-0.0 -0.947 64.8 22.3-161.7 136.7 25.0 -14.8 54.4 102 113 A P S S- 0 0 51 0, 0.0 39,-2.1 0, 0.0 2,-0.5 0.531 72.0-178.0 -79.8 137.4 22.4 -15.3 53.0 103 114 A V E -N 140 0E 0 125,-0.5 125,-2.5 -3,-0.3 2,-0.3 -0.895 15.2-156.2 -94.8 126.5 20.9 -11.8 53.4 104 115 A H E -NO 139 227E 29 35,-3.2 35,-2.5 -2,-0.5 2,-0.2 -0.781 12.8-138.8-105.2 145.4 17.4 -11.7 51.9 105 116 A F E - O 0 226E 2 121,-1.8 121,-0.5 -2,-0.3 2,-0.2 -0.553 16.8-167.0 -79.6 158.4 15.2 -8.9 50.5 106 117 A E - 0 0 15 -2,-0.2 31,-2.7 119,-0.1 2,-0.3 -0.745 10.3-148.8-149.4 107.3 11.5 -9.0 51.5 107 118 A G E +H 136 0A 0 -2,-0.2 2,-0.3 29,-0.2 29,-0.2 -0.589 28.7 172.6 -75.4 131.3 9.1 -6.8 49.6 108 119 A E E -H 135 0A 0 27,-2.5 27,-2.9 -2,-0.3 2,-0.3 -1.000 38.8-116.3-145.5 142.1 6.2 -5.6 51.7 109 120 A L E -H 134 0A 0 111,-0.5 110,-2.3 -2,-0.3 2,-0.4 -0.582 39.6-149.8 -66.6 131.9 3.2 -3.3 51.8 110 121 A A E -HI 133 218A 0 23,-3.0 23,-2.5 -2,-0.3 2,-0.4 -0.922 7.0-149.6-113.9 137.2 3.8 -0.8 54.5 111 122 A I E -HI 132 217A 0 106,-2.8 106,-2.4 -2,-0.4 2,-0.5 -0.831 7.5-155.3 -95.9 133.9 1.2 1.0 56.7 112 123 A V E -HI 131 216A 0 19,-2.6 18,-2.1 -2,-0.4 19,-1.4 -0.975 15.1-136.4-111.1 123.7 1.9 4.5 57.9 113 124 A I E -H 129 0A 0 102,-2.3 101,-3.4 -2,-0.5 16,-0.3 -0.566 13.9-166.1 -77.5 136.3 -0.0 5.4 61.1 114 125 A G + 0 0 11 14,-2.9 15,-0.2 -2,-0.3 -1,-0.1 0.550 63.5 16.8-105.9 -11.5 -1.4 9.0 61.0 115 126 A R S S- 0 0 128 13,-0.8 -1,-0.2 97,-0.1 96,-0.1 -0.989 91.1 -77.5-156.3 160.9 -2.4 9.6 64.6 116 127 A P + 0 0 87 0, 0.0 2,-0.3 0, 0.0 96,-0.2 -0.348 61.8 163.8 -61.4 135.1 -1.8 8.4 68.1 117 128 A C B +P 211 0F 12 94,-2.3 94,-3.1 3,-0.0 2,-0.3 -0.992 23.0 174.5-156.9 160.2 -3.9 5.2 68.7 118 129 A K S S+ 0 0 132 -2,-0.3 89,-0.2 92,-0.2 92,-0.1 -0.960 71.0 15.3-162.7 140.4 -4.3 2.2 70.9 119 130 A D S S+ 0 0 108 87,-2.8 2,-0.3 -2,-0.3 88,-0.1 0.856 77.7 172.1 56.2 42.7 -6.9 -0.6 71.1 120 131 A V - 0 0 10 82,-0.3 -1,-0.2 83,-0.1 86,-0.2 -0.661 30.3-126.9 -82.8 134.6 -8.2 0.2 67.6 121 132 A S >> - 0 0 44 -2,-0.3 4,-0.6 1,-0.1 3,-0.6 -0.416 26.2-110.9 -72.4 158.1 -10.8 -2.3 66.1 122 133 A A G >4 S+ 0 0 35 1,-0.2 3,-1.1 2,-0.2 4,-0.4 0.902 120.0 53.1 -56.2 -42.4 -10.0 -3.6 62.6 123 134 A A G 34 S+ 0 0 87 1,-0.3 3,-0.3 2,-0.1 -1,-0.2 0.772 108.1 50.9 -66.0 -27.5 -12.9 -1.6 61.2 124 135 A Q G X4 S+ 0 0 101 -3,-0.6 3,-1.2 1,-0.2 4,-0.4 0.521 82.9 93.4 -84.7 -6.3 -11.5 1.6 62.7 125 136 A A G X< S+ 0 0 1 -3,-1.1 3,-2.5 -4,-0.6 4,-0.5 0.908 76.5 62.7 -55.7 -43.5 -8.0 1.1 61.3 126 137 A V G > S+ 0 0 105 -4,-0.4 3,-0.8 -3,-0.3 -1,-0.3 0.809 98.4 55.9 -48.1 -37.7 -8.8 3.2 58.2 127 138 A D G < S+ 0 0 99 -3,-1.2 -1,-0.3 1,-0.2 -2,-0.2 0.554 111.3 44.4 -76.3 -6.0 -9.4 6.3 60.5 128 139 A N G < S+ 0 0 9 -3,-2.5 -14,-2.9 -4,-0.4 -13,-0.8 0.370 92.4 95.6-116.1 3.9 -5.9 5.9 62.0 129 140 A I E < -H 113 0A 24 -3,-0.8 -16,-0.3 -4,-0.5 3,-0.1 -0.863 49.8-167.2-107.0 118.2 -3.9 5.3 58.8 130 141 A L E - 0 0 23 -18,-2.1 2,-0.3 -2,-0.6 -1,-0.2 0.941 62.0 -83.0 -61.9 -51.5 -2.1 8.1 57.0 131 142 A G E -H 112 0A 1 -19,-1.4 -19,-2.6 38,-0.1 2,-0.4 -0.973 49.1 -61.6 171.3-156.6 -1.6 5.9 54.0 132 143 A Y E +HJ 111 167A 18 35,-2.4 35,-3.2 -2,-0.3 2,-0.2 -0.916 38.7 158.8-126.8 145.6 0.6 3.2 52.3 133 144 A T E -H 110 0A 0 -23,-2.5 -23,-3.0 -2,-0.4 2,-0.4 -0.692 38.8 -87.9-143.0-165.5 4.1 2.9 51.2 134 145 A I E -HJ 109 163A 0 29,-1.0 29,-2.1 -25,-0.2 2,-0.3 -0.922 32.2-170.5-118.7 140.3 6.7 0.2 50.4 135 146 A G E -HJ 108 162A 0 -27,-2.9 -27,-2.5 -2,-0.4 2,-0.5 -0.945 17.0-150.7-124.5 152.3 9.1 -1.5 52.8 136 147 A N E -H 107 0A 0 25,-2.0 2,-2.1 -2,-0.3 -29,-0.2 -0.935 12.8-156.1-117.2 103.1 12.0 -3.9 52.2 137 148 A D - 0 0 0 -31,-2.7 23,-0.2 -2,-0.5 -33,-0.1 -0.485 17.0-160.5 -79.1 75.3 12.3 -6.1 55.3 138 149 A V - 0 0 0 -2,-2.1 2,-0.4 21,-1.5 -33,-0.2 -0.368 12.2-171.9 -66.1 134.1 16.0 -7.0 54.8 139 150 A S E -N 104 0E 0 -35,-2.5 -35,-3.2 -2,-0.1 2,-1.1 -0.978 29.6-144.6-141.6 120.0 16.9 -10.1 56.8 140 151 A A E > -N 103 0E 0 13,-2.1 4,-1.6 -2,-0.4 -37,-0.2 -0.741 21.0-167.0 -79.3 100.3 20.1 -11.9 57.7 141 152 A R H > S+ 0 0 51 -39,-2.1 4,-2.0 -2,-1.1 5,-0.2 0.823 82.0 55.9 -63.2 -37.7 18.8 -15.6 57.5 142 153 A D H > S+ 0 0 53 -40,-0.5 4,-2.4 1,-0.2 -1,-0.2 0.916 110.0 47.3 -59.1 -42.3 21.9 -17.2 59.2 143 154 A Q H > S+ 0 0 6 -3,-0.2 4,-2.8 2,-0.2 -2,-0.2 0.802 107.9 55.9 -71.2 -31.9 21.4 -14.8 62.2 144 155 A Q H X S+ 0 0 27 -4,-1.6 4,-1.9 2,-0.2 -1,-0.2 0.938 113.1 40.2 -61.0 -50.1 17.7 -15.6 62.4 145 156 A K H < S+ 0 0 190 -4,-2.0 -2,-0.2 2,-0.2 -1,-0.2 0.908 117.7 49.8 -67.4 -41.7 18.3 -19.3 62.7 146 157 A S H < S+ 0 0 93 -4,-2.4 -2,-0.2 -5,-0.2 -1,-0.2 0.921 120.6 32.4 -65.7 -46.7 21.3 -18.7 65.0 147 158 A D H < S- 0 0 67 -4,-2.8 2,-2.1 2,-0.2 -1,-0.2 0.674 83.0-149.4 -80.0 -24.8 19.4 -16.3 67.4 148 159 A G S < S+ 0 0 47 -4,-1.9 -1,-0.1 -5,-0.2 2,-0.1 -0.403 80.2 84.1 72.6 -62.2 15.9 -17.8 67.3 149 160 A Q S S- 0 0 147 -2,-2.1 4,-0.4 1,-0.1 -2,-0.2 -0.451 78.7-144.6 -61.6 143.4 14.7 -14.2 67.9 150 161 A W S > S+ 0 0 81 1,-0.2 4,-2.0 2,-0.1 5,-0.2 0.514 72.8 98.8 -92.6 -6.8 14.6 -12.3 64.7 151 162 A T H > S+ 0 0 82 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.903 85.6 39.4 -51.4 -57.0 15.7 -8.9 66.1 152 163 A R H >4 S+ 0 0 107 1,-0.2 3,-1.3 2,-0.2 4,-0.5 0.947 113.9 53.9 -62.5 -49.0 19.3 -8.9 65.1 153 164 A A H 34 S+ 0 0 0 -4,-0.4 -13,-2.1 1,-0.3 3,-0.3 0.848 121.1 32.3 -51.1 -37.7 18.8 -10.5 61.7 154 165 A K H 3< S+ 0 0 4 -4,-2.0 -1,-0.3 -15,-0.2 -2,-0.2 0.421 108.9 69.7-102.1 2.9 16.3 -7.8 60.8 155 166 A G << + 0 0 18 -3,-1.3 -1,-0.2 -4,-0.8 -2,-0.1 0.335 60.2 124.4-113.1 4.3 17.8 -4.9 62.7 156 167 A H S > S- 0 0 46 -4,-0.5 3,-2.0 -3,-0.3 4,-0.1 -0.285 75.9 -86.9 -63.9 149.1 21.0 -3.9 61.0 157 168 A D T 3 S+ 0 0 104 1,-0.2 -62,-0.4 2,-0.1 -71,-0.2 -0.342 117.5 20.2 -52.6 138.3 21.5 -0.3 59.8 158 169 A T T 3 S+ 0 0 16 -73,-0.6 -1,-0.2 -71,-0.2 -70,-0.2 0.343 89.3 114.5 81.9 -1.2 20.0 0.0 56.2 159 170 A F < + 0 0 0 -3,-2.0 -21,-1.5 1,-0.2 -72,-0.2 0.336 67.9 60.3 -87.0 8.8 17.9 -3.1 56.6 160 171 A C E +l 87 0C 0 -74,-2.7 -72,-1.3 -23,-0.2 -1,-0.2 -0.423 65.5 179.0-131.9 63.9 14.6 -1.2 56.4 161 172 A P E -l 88 0C 0 0, 0.0 -25,-2.0 0, 0.0 2,-0.3 -0.385 13.0-177.6 -54.0 140.8 14.4 0.7 53.0 162 173 A V E - J 0 135A 0 -74,-2.3 -27,-0.2 -27,-0.2 -103,-0.1 -0.994 22.0 -6.1-145.7 141.1 11.1 2.6 52.9 163 174 A G E - J 0 134A 0 -29,-2.1 -29,-1.0 -2,-0.3 81,-0.2 -0.931 14.1-161.6 145.3-164.1 9.4 4.7 50.2 164 175 A P E S- 0 0 5 0, 0.0 2,-0.3 0, 0.0 -108,-0.1 -0.986 92.8 -49.5 -77.5 -17.5 9.2 6.1 47.7 165 176 A W E - 0 0 12 -160,-0.1 2,-0.5 -33,-0.1 -160,-0.2 -0.946 54.7 -94.4-168.8 173.0 6.3 8.1 49.2 166 177 A I E -A 4 0A 0 -162,-3.1 -162,-3.2 -2,-0.3 2,-0.6 -0.898 28.3-150.5-109.9 123.8 3.1 7.5 51.2 167 178 A V E -AJ 3 132A 10 -35,-3.2 -35,-2.4 -2,-0.5 3,-0.3 -0.848 7.6-168.1 -99.9 123.3 -0.2 7.2 49.2 168 179 A T S S+ 0 0 44 -166,-2.5 -1,-0.1 -2,-0.6 -165,-0.1 0.665 78.3 42.1 -85.6 -18.6 -3.1 8.4 51.2 169 180 A D S S+ 0 0 95 -167,-0.3 -1,-0.2 -37,-0.1 2,-0.2 0.390 81.2 117.9-113.1 5.9 -6.1 7.3 49.2 170 181 A V - 0 0 23 -3,-0.3 70,-0.0 70,-0.1 71,-0.0 -0.479 60.5-131.1 -84.9 141.8 -5.1 3.8 48.0 171 182 A D > - 0 0 109 -2,-0.2 3,-0.5 1,-0.1 -1,-0.1 -0.836 14.9-161.6 -91.1 119.6 -7.2 0.8 49.0 172 183 A P G > + 0 0 21 0, 0.0 3,-0.6 0, 0.0 -1,-0.1 0.450 65.3 94.8 -80.3 -2.1 -4.7 -1.9 50.3 173 184 A A G 3 S+ 0 0 63 1,-0.2 21,-0.2 19,-0.1 17,-0.0 0.784 99.2 10.8 -66.9 -33.1 -7.1 -4.9 49.9 174 185 A D G < S+ 0 0 79 -3,-0.5 2,-0.4 17,-0.1 -1,-0.2 -0.439 81.4 141.7-149.0 69.3 -6.0 -6.1 46.4 175 186 A L < - 0 0 14 -3,-0.6 16,-2.9 -2,-0.0 2,-0.2 -0.896 48.3-115.9-115.0 142.3 -2.8 -4.6 45.1 176 187 A E E -Q 190 0G 49 -2,-0.4 63,-2.3 14,-0.2 2,-0.4 -0.499 25.1-163.1 -71.5 142.1 -0.1 -6.3 43.1 177 188 A L E +QR 189 238G 0 12,-3.9 12,-2.5 61,-0.2 2,-0.4 -0.996 9.8 179.2-125.1 130.3 3.4 -6.5 44.6 178 189 A R E -QR 188 237G 70 59,-2.9 59,-3.4 -2,-0.4 2,-0.4 -0.993 9.0-164.6-134.5 127.4 6.4 -7.3 42.5 179 190 A T E -QR 187 236G 0 8,-2.0 7,-3.3 -2,-0.4 8,-1.3 -0.939 7.5-171.9-113.1 133.3 10.0 -7.5 43.5 180 191 A E E -QR 185 235G 42 55,-3.3 55,-2.6 -2,-0.4 2,-0.5 -0.948 14.8-163.4-123.0 143.4 13.0 -7.5 41.1 181 192 A V E > S-QR 184 234G 12 3,-2.3 3,-1.5 -2,-0.4 53,-0.2 -0.984 89.1 -16.6-122.7 112.7 16.7 -8.1 41.7 182 193 A N T 3 S- 0 0 100 51,-2.6 -1,-0.1 -2,-0.5 52,-0.1 0.894 129.9 -53.7 55.8 42.9 18.6 -6.8 38.7 183 194 A G T 3 S+ 0 0 56 50,-0.3 2,-0.5 1,-0.2 -1,-0.3 0.429 111.9 121.1 77.2 -0.2 15.4 -6.7 36.6 184 195 A A E < -Q 181 0G 45 -3,-1.5 -3,-2.3 1,-0.0 2,-0.3 -0.866 66.3-121.3-101.2 127.3 14.5 -10.3 37.3 185 196 A V E +Q 180 0G 71 -2,-0.5 -5,-0.2 -5,-0.2 3,-0.1 -0.513 40.9 160.1 -72.7 125.8 11.2 -10.9 39.0 186 197 A K E + 0 0 106 -7,-3.3 2,-0.4 1,-0.4 -6,-0.2 0.705 67.0 34.5-114.4 -40.2 11.4 -12.8 42.3 187 198 A Q E +Q 179 0G 1 -8,-1.3 -8,-2.0 2,-0.0 -1,-0.4 -0.968 59.6 165.4-119.3 141.2 8.2 -12.0 44.1 188 199 A H E +Q 178 0G 120 -2,-0.4 2,-0.3 35,-0.4 -10,-0.2 -0.719 27.1 115.9-158.3 95.9 4.9 -11.5 42.2 189 200 A A E -Q 177 0G 19 -12,-2.5 -12,-3.9 -2,-0.2 2,-0.4 -0.937 53.6-107.7-156.2 172.3 1.7 -11.6 44.2 190 201 A R E > -Q 176 0G 80 -2,-0.3 3,-2.1 -14,-0.3 -14,-0.2 -0.883 23.8-126.2-113.6 145.8 -1.3 -9.6 45.3 191 202 A T G > S+ 0 0 4 -16,-2.9 3,-1.8 -2,-0.4 -17,-0.1 0.643 103.7 80.4 -62.3 -13.6 -2.0 -8.2 48.8 192 203 A S G 3 S+ 0 0 67 1,-0.3 -1,-0.3 -17,-0.2 -18,-0.1 0.607 82.8 65.7 -68.1 -9.6 -5.4 -10.0 48.6 193 204 A L G < S+ 0 0 86 -3,-2.1 -121,-2.5 -121,-0.1 -1,-0.3 0.355 73.4 123.8 -91.7 3.0 -3.4 -13.1 49.6 194 205 A M B < -K 71 0B 23 -3,-1.8 -123,-0.3 -123,-0.2 3,-0.1 -0.479 56.6-148.7 -63.9 133.7 -2.6 -11.7 53.0 195 206 A I S S+ 0 0 75 -125,-2.3 2,-0.5 1,-0.2 -1,-0.1 0.944 92.6 31.4 -67.2 -50.3 -3.6 -14.0 55.8 196 207 A H S S- 0 0 27 -126,-0.3 -1,-0.2 23,-0.2 -3,-0.0 -0.950 90.2-142.0-111.9 123.5 -4.3 -11.0 58.1 197 208 A D > - 0 0 100 -2,-0.5 4,-2.3 -3,-0.1 5,-0.2 -0.104 33.5 -87.3 -78.7 179.4 -5.5 -7.9 56.3 198 209 A V H > S+ 0 0 13 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.907 127.3 47.8 -55.6 -47.4 -4.5 -4.3 57.2 199 210 A G H > S+ 0 0 13 1,-0.2 4,-2.8 2,-0.2 -1,-0.2 0.903 112.1 49.4 -61.4 -43.9 -7.3 -3.8 59.7 200 211 A A H > S+ 0 0 26 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.879 112.1 49.7 -62.6 -37.4 -6.6 -7.1 61.5 201 212 A I H X S+ 0 0 0 -4,-2.3 4,-2.9 2,-0.2 5,-0.3 0.949 113.5 44.2 -66.9 -48.6 -2.9 -6.2 61.6 202 213 A V H X S+ 0 0 0 -4,-2.7 4,-2.5 1,-0.2 -82,-0.3 0.903 113.8 51.2 -64.2 -40.8 -3.6 -2.8 63.1 203 214 A E H X S+ 0 0 89 -4,-2.8 4,-1.0 -5,-0.2 -2,-0.2 0.943 113.6 45.4 -57.4 -50.0 -6.1 -4.2 65.5 204 215 A W H >X S+ 0 0 87 -4,-2.6 3,-0.6 1,-0.2 4,-0.5 0.958 117.4 41.4 -60.0 -55.0 -3.6 -6.8 66.7 205 216 A I H >X S+ 0 0 0 -4,-2.9 4,-2.9 1,-0.2 3,-1.4 0.893 112.5 53.1 -62.5 -42.1 -0.6 -4.5 67.1 206 217 A S H 3< S+ 0 0 1 -4,-2.5 -87,-2.8 1,-0.3 -1,-0.2 0.673 101.8 60.7 -74.9 -14.6 -2.6 -1.6 68.7 207 218 A A H << S+ 0 0 64 -4,-1.0 -1,-0.3 -3,-0.6 -2,-0.2 0.652 114.1 37.6 -75.6 -19.7 -3.9 -4.0 71.3 208 219 A V H << S+ 0 0 93 -3,-1.4 2,-0.3 -4,-0.5 -2,-0.2 0.863 127.9 7.8 -92.7 -53.5 -0.2 -4.6 72.3 209 220 A M S < S- 0 0 46 -4,-2.9 -1,-0.3 -92,-0.0 -90,-0.1 -0.963 76.0 -98.9-140.4 145.6 1.3 -1.1 71.9 210 221 A T - 0 0 62 -2,-0.3 2,-0.4 -3,-0.1 -92,-0.2 -0.379 37.1-145.2 -57.7 134.8 0.4 2.5 71.3 211 222 A L B -P 117 0F 0 -94,-3.1 -94,-2.3 -96,-0.1 -1,-0.0 -0.894 13.7-153.3-107.7 136.3 1.0 3.5 67.7 212 223 A L > - 0 0 70 -2,-0.4 3,-2.7 -96,-0.2 -99,-0.3 -0.762 32.3 -82.5-111.7 154.1 2.3 7.0 67.0 213 224 A P T 3 S+ 0 0 47 0, 0.0 -99,-0.2 0, 0.0 -151,-0.2 -0.321 121.0 23.7 -53.1 127.0 1.9 9.3 63.9 214 225 A G T 3 S+ 0 0 1 -101,-3.4 -100,-0.1 1,-0.3 -151,-0.0 0.164 86.7 142.0 97.6 -17.6 4.6 8.2 61.5 215 226 A D < - 0 0 0 -3,-2.7 -102,-2.3 -154,-0.2 2,-0.4 -0.279 43.0-139.0 -55.0 139.7 4.9 4.6 62.9 216 227 A L E -gI 64 112A 0 -153,-1.9 -151,-2.9 -104,-0.2 2,-0.5 -0.848 14.2-165.3-105.0 140.4 5.5 2.1 60.2 217 228 A I E -gI 65 111A 0 -106,-2.4 -106,-2.8 -2,-0.4 2,-0.6 -0.977 8.2-154.6-123.1 117.7 4.0 -1.3 60.0 218 229 A L E -gI 66 110A 0 -153,-2.4 -151,-2.6 -2,-0.5 -108,-0.2 -0.826 8.0-156.6 -89.6 123.8 5.4 -3.9 57.5 219 230 A T - 0 0 0 -110,-2.3 -23,-0.2 -2,-0.6 -1,-0.1 0.270 43.9 -87.4 -94.9 10.5 2.7 -6.4 56.7 220 231 A G - 0 0 0 -111,-0.1 -111,-0.5 -114,-0.1 -1,-0.3 -0.219 40.3 -94.6 106.2 164.1 4.7 -9.4 55.6 221 232 A T - 0 0 24 -153,-0.2 -151,-0.4 -113,-0.1 -150,-0.3 -0.907 27.9-127.0-119.6 143.6 6.2 -10.7 52.4 222 233 A P - 0 0 6 0, 0.0 3,-0.3 0, 0.0 -115,-0.1 -0.128 48.5 -63.6 -71.7 179.4 4.9 -13.1 49.7 223 234 A A S S+ 0 0 92 1,-0.2 -35,-0.4 -35,-0.1 -151,-0.0 -0.156 105.8 62.3 -56.5 155.2 6.6 -16.2 48.3 224 235 A G + 0 0 36 1,-0.2 -1,-0.2 -37,-0.1 -45,-0.0 0.565 58.7 163.1 103.1 12.6 9.9 -15.7 46.4 225 236 A V + 0 0 53 -3,-0.3 -1,-0.2 -4,-0.1 -119,-0.1 -0.261 16.4 161.8 -54.4 147.9 12.3 -14.3 49.0 226 237 A G E -O 105 0E 9 -121,-0.5 -121,-1.8 -123,-0.0 -40,-0.0 -0.978 34.7 -66.4-165.5 175.1 15.9 -14.6 48.1 227 238 A P E -O 104 0E 76 0, 0.0 2,-0.3 0, 0.0 -123,-0.2 -0.276 31.1-158.8 -75.3 149.9 19.5 -13.4 48.5 228 239 A I - 0 0 0 -125,-2.5 -125,-0.5 4,-0.1 2,-0.3 -0.950 14.9-178.4-122.0 148.8 21.1 -10.1 47.8 229 240 A E > - 0 0 76 -2,-0.3 3,-2.1 -127,-0.1 19,-0.1 -0.871 41.2 -60.4-138.4 167.8 24.8 -9.5 47.2 230 241 A D T 3 S+ 0 0 70 -2,-0.3 19,-0.2 1,-0.2 3,-0.1 -0.259 121.9 24.1 -48.6 130.6 27.3 -6.7 46.5 231 242 A G T 3 S+ 0 0 58 17,-2.1 -1,-0.2 1,-0.3 18,-0.1 0.223 93.6 125.4 95.4 -14.2 26.4 -5.0 43.2 232 243 A D < - 0 0 27 -3,-2.1 16,-1.9 15,-0.1 2,-0.4 -0.341 46.5-151.4 -76.2 158.0 22.7 -6.0 43.2 233 244 A T E - S 0 247G 56 14,-0.2 -51,-2.6 -3,-0.1 2,-0.5 -0.999 9.1-160.5-124.9 132.1 19.8 -3.6 42.8 234 245 A V E -RS 181 246G 0 12,-2.6 12,-2.5 -2,-0.4 2,-0.5 -0.946 7.5-175.0-116.4 127.3 16.4 -4.5 44.4 235 246 A S E -RS 180 245G 25 -55,-2.6 -55,-3.3 -2,-0.5 2,-0.5 -0.990 5.4-168.9-123.9 124.8 13.2 -2.9 43.2 236 247 A I E -RS 179 244G 0 8,-2.9 8,-3.3 -2,-0.5 2,-0.5 -0.965 8.3-168.0-112.8 125.4 9.8 -3.5 44.9 237 248 A T E -RS 178 243G 23 -59,-3.4 -59,-2.9 -2,-0.5 2,-0.5 -0.957 5.0-170.4-115.3 129.6 6.8 -2.2 43.0 238 249 A I E >> -RS 177 242G 1 4,-2.4 3,-2.1 -2,-0.5 4,-1.8 -0.989 31.6-112.0-117.9 127.6 3.3 -2.0 44.5 239 250 A E T 34 S+ 0 0 92 -63,-2.3 4,-0.0 -2,-0.5 -64,-0.0 -0.256 103.1 16.8 -51.1 133.3 0.3 -1.1 42.4 240 251 A G T 34 S+ 0 0 41 1,-0.1 -1,-0.3 -70,-0.0 -70,-0.1 0.404 127.4 57.2 80.3 -2.6 -1.2 2.3 43.2 241 252 A I T <4 S- 0 0 0 -3,-2.1 2,-0.3 1,-0.2 -2,-0.2 0.687 92.7-125.1-119.8 -68.1 2.0 3.3 45.0 242 253 A G E < -S 238 0G 5 -4,-1.8 -4,-2.4 -79,-0.1 2,-0.4 -0.994 36.0 -47.8 149.5-150.4 5.2 3.1 43.0 243 254 A T E -S 237 0G 58 -2,-0.3 2,-0.6 -6,-0.2 -6,-0.3 -0.988 30.1-156.6-132.4 127.3 8.6 1.5 43.1 244 255 A L E -S 236 0G 0 -8,-3.3 -8,-2.9 -2,-0.4 2,-0.4 -0.932 22.7-176.1-100.1 119.9 11.1 1.4 46.0 245 256 A T E +S 235 0G 35 -2,-0.6 -154,-3.3 -10,-0.2 -10,-0.2 -0.965 8.0 171.0-124.2 132.1 14.6 0.8 44.6 246 257 A N E -S 234 0G 0 -12,-2.5 -12,-2.6 -2,-0.4 -154,-0.1 -0.994 25.0-135.1-140.5 134.6 17.9 0.3 46.5 247 258 A P E -S 233 0G 42 0, 0.0 -153,-2.5 0, 0.0 2,-0.4 -0.308 23.8-136.1 -74.3 168.4 21.4 -0.7 45.5 248 259 A V E +m 94 0D 2 -16,-1.9 -17,-2.1 -155,-0.2 2,-0.3 -0.985 21.8 177.1-128.5 136.0 23.3 -3.3 47.6 249 260 A V E -m 95 0D 45 -155,-2.7 -153,-2.7 -2,-0.4 2,-0.5 -0.994 22.5-136.6-133.3 144.1 26.9 -3.2 48.8 250 261 A R E > -m 96 0D 23 -2,-0.3 3,-1.1 -155,-0.2 -152,-0.1 -0.894 27.8-117.8 -98.9 129.7 28.8 -5.6 51.0 251 262 A K T 3 S+ 0 0 115 -155,-2.8 -21,-0.1 -2,-0.5 -1,-0.0 -0.299 96.5 34.1 -59.1 144.0 31.0 -4.1 53.7 252 263 A G T 3 0 0 82 1,-0.3 -1,-0.2 -155,-0.0 0, 0.0 0.410 360.0 360.0 90.7 1.0 34.7 -4.9 53.4 253 264 A K < 0 0 171 -3,-1.1 -1,-0.3 0, 0.0 -155,-0.0 -0.420 360.0 360.0 -81.9 360.0 34.8 -5.0 49.5