==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 13-JUN-99 1QRF . COMPND 2 MOLECULE: CARBONIC ANHYDRASE; . SOURCE 2 ORGANISM_SCIENTIFIC: METHANOSARCINA THERMOPHILA; . AUTHOR T.M.IVERSON,B.E.ALBER,C.KISKER,J.G.FERRY,D.C.REES . 206 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9580.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 161 78.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 67 32.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 4.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 22 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 27 13.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 19 9.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 11 4 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 8 A F 0 0 237 0, 0.0 2,-0.4 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 152.3 38.0 71.6 43.2 2 9 A S - 0 0 67 1,-0.1 3,-0.0 2,-0.0 30,-0.0 -0.824 360.0-151.5-106.0 145.8 34.8 70.5 41.5 3 10 A N S S+ 0 0 33 -2,-0.4 30,-2.6 1,-0.1 2,-0.6 0.626 89.1 63.2 -89.4 -13.6 31.8 69.2 43.4 4 11 A I E S+a 33 0A 62 28,-0.2 2,-0.3 30,-0.1 30,-0.2 -0.966 80.1 156.1-108.6 112.1 30.6 67.0 40.5 5 12 A R E -a 34 0A 132 28,-2.3 30,-2.6 -2,-0.6 2,-0.1 -0.943 44.5-102.1-140.2 161.7 33.4 64.5 40.0 6 13 A E - 0 0 52 -2,-0.3 12,-0.2 28,-0.2 48,-0.1 -0.413 43.7-108.2 -78.4 160.1 34.4 61.0 38.7 7 14 A N - 0 0 6 10,-1.4 2,-0.1 46,-0.1 -1,-0.1 -0.454 41.0 -99.4 -84.5 161.2 34.9 58.2 41.1 8 15 A P - 0 0 73 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.413 35.0 -99.2 -82.7 155.5 38.5 56.9 41.8 9 16 A V + 0 0 103 -2,-0.1 6,-0.0 7,-0.1 45,-0.0 -0.567 55.8 156.8 -73.2 132.9 40.1 53.9 40.2 10 17 A T B > -M 13 0B 33 3,-1.2 3,-1.6 -2,-0.3 -3,-0.0 -0.918 60.1 -84.4-142.3-179.9 40.0 50.9 42.7 11 18 A P T 3 S+ 0 0 125 0, 0.0 -2,-0.0 0, 0.0 72,-0.0 0.712 132.0 39.9 -62.9 -23.1 40.1 47.1 42.3 12 19 A W T 3 S+ 0 0 64 1,-0.2 66,-0.1 69,-0.1 -3,-0.0 0.330 114.3 57.1-107.2 5.5 36.3 47.1 41.6 13 20 A N B < +M 10 0B 7 -3,-1.6 -3,-1.2 1,-0.1 -1,-0.2 -0.637 51.9 158.1-141.1 77.1 36.4 50.2 39.4 14 21 A P S S+ 0 0 111 0, 0.0 -1,-0.1 0, 0.0 -5,-0.1 0.878 75.9 42.2 -65.1 -41.8 38.8 49.9 36.4 15 22 A E S S- 0 0 67 -7,-0.1 -6,-0.0 -6,-0.0 0, 0.0 -0.902 87.1-140.7-116.5 102.3 37.1 52.5 34.4 16 23 A P - 0 0 64 0, 0.0 2,-0.3 0, 0.0 -7,-0.1 -0.211 15.4-150.1 -58.0 146.5 36.0 55.6 36.3 17 24 A S - 0 0 36 -9,-0.1 -10,-1.4 -12,-0.1 18,-0.3 -0.928 4.8-144.6-124.8 147.1 32.7 57.3 35.6 18 25 A A - 0 0 65 -2,-0.3 -12,-0.2 -12,-0.2 19,-0.2 -0.761 39.6 -88.7-103.8 149.1 31.4 60.8 35.8 19 26 A P - 0 0 20 0, 0.0 2,-0.7 0, 0.0 19,-0.2 -0.305 28.7-141.7 -56.2 139.4 27.8 61.7 36.8 20 27 A V E +b 38 0A 98 17,-3.0 19,-2.8 2,-0.0 2,-0.5 -0.948 30.5 179.3-103.5 104.1 25.2 62.0 34.0 21 28 A I E -b 39 0A 43 -2,-0.7 19,-0.2 17,-0.2 20,-0.1 -0.960 29.9-119.7-117.7 126.9 23.0 64.9 35.1 22 29 A D > - 0 0 54 17,-2.2 3,-2.0 -2,-0.5 21,-0.1 -0.244 24.6-124.2 -60.1 141.7 20.1 66.3 33.2 23 30 A P T 3 S+ 0 0 109 0, 0.0 -1,-0.1 0, 0.0 18,-0.1 0.774 111.0 58.2 -59.1 -22.6 20.6 69.9 32.2 24 31 A T T 3 S+ 0 0 53 2,-0.1 2,-0.2 0, 0.0 179,-0.1 0.538 86.4 96.2 -87.2 -6.0 17.4 70.8 34.0 25 32 A A < - 0 0 2 -3,-2.0 2,-0.5 17,-0.2 19,-0.2 -0.507 68.0-140.0 -82.9 153.2 18.6 69.4 37.3 26 33 A Y E -n 44 0C 20 17,-2.8 19,-2.4 -2,-0.2 2,-0.5 -0.983 13.4-169.4-116.2 124.3 20.1 71.8 39.9 27 34 A I E -n 45 0C 25 -2,-0.5 19,-0.2 17,-0.2 -24,-0.1 -0.964 24.7-128.7-111.6 112.2 23.1 70.7 41.9 28 35 A D > - 0 0 13 17,-2.7 3,-2.1 -2,-0.5 20,-0.1 -0.269 17.8-121.5 -58.3 148.6 23.9 73.1 44.8 29 36 A P T 3 S+ 0 0 85 0, 0.0 -1,-0.1 0, 0.0 17,-0.1 0.822 114.0 51.2 -60.7 -25.9 27.5 74.3 44.9 30 37 A Q T 3 S+ 0 0 126 2,-0.1 18,-2.3 -27,-0.0 2,-0.2 0.203 92.7 92.7-101.6 20.9 27.9 72.8 48.4 31 38 A A < - 0 0 4 -3,-2.1 2,-0.4 16,-0.3 19,-0.2 -0.686 68.3-140.7 -96.7 162.7 26.5 69.4 47.4 32 39 A S E + c 0 50A 28 17,-2.3 19,-2.9 -2,-0.2 2,-0.5 -0.999 19.1 178.8-125.3 130.8 28.8 66.6 46.3 33 40 A V E +ac 4 51A 0 -30,-2.6 -28,-2.3 -2,-0.4 2,-0.4 -0.982 13.0 177.9-137.5 110.2 28.0 64.2 43.5 34 41 A I E -ac 5 52A 14 17,-2.8 19,-3.1 -2,-0.5 -28,-0.2 -0.968 34.8 -25.2-123.5 135.5 30.7 61.6 42.7 35 42 A G E S+ c 0 53A 0 -30,-2.6 2,-1.7 -2,-0.4 19,-0.2 -0.441 106.3 14.0 86.4-141.6 30.9 58.7 40.3 36 43 A E S S+ 0 0 62 17,-1.5 23,-2.1 -2,-0.2 2,-0.4 -0.605 84.0 140.4 -84.7 85.6 28.5 56.5 38.5 37 44 A V E - d 0 59A 2 -2,-1.7 -17,-3.0 21,-0.2 2,-0.5 -0.986 39.7-157.9-132.2 138.5 25.3 58.5 39.1 38 45 A T E -bd 20 60A 53 21,-2.2 23,-2.9 -2,-0.4 2,-0.5 -0.987 10.8-171.4-116.7 125.2 22.3 59.3 37.0 39 46 A I E -bd 21 61A 3 -19,-2.8 -17,-2.2 -2,-0.5 23,-0.2 -0.982 15.3-143.9-116.8 125.8 20.3 62.4 37.9 40 47 A G > - 0 0 9 21,-2.7 3,-1.0 -2,-0.5 -18,-0.1 0.120 32.8 -63.0 -84.4-177.2 17.0 63.0 36.1 41 48 A A T 3 S+ 0 0 16 1,-0.2 23,-3.3 -17,-0.1 24,-0.3 -0.343 112.2 10.3 -68.4 149.2 15.2 66.1 34.9 42 49 A N T 3 S+ 0 0 49 1,-0.2 2,-0.3 21,-0.2 -1,-0.2 0.688 87.6 150.1 59.9 26.4 14.0 68.8 37.3 43 50 A V < - 0 0 0 -3,-1.0 -17,-2.8 21,-0.1 2,-0.5 -0.626 35.0-150.4 -90.2 140.7 15.8 67.3 40.3 44 51 A M E -no 26 66C 6 21,-1.2 23,-2.8 -2,-0.3 2,-0.6 -0.965 8.7-170.2-109.5 127.6 17.0 69.5 43.1 45 52 A V E -no 27 67C 0 -19,-2.4 -17,-2.7 -2,-0.5 23,-0.2 -0.981 20.9-150.3-116.6 113.6 20.1 68.5 45.1 46 53 A S > - 0 0 10 21,-2.7 3,-1.7 -2,-0.6 24,-0.2 -0.151 29.2 -64.4 -85.0 170.2 20.5 70.8 48.1 47 54 A P T 3 S+ 0 0 33 0, 0.0 23,-1.0 0, 0.0 -16,-0.3 -0.256 116.9 12.8 -49.2 138.9 23.4 72.1 50.2 48 55 A M T 3 S+ 0 0 119 -18,-2.3 -17,-0.2 1,-0.3 2,-0.1 0.391 87.5 139.5 74.0 2.9 25.5 69.4 52.1 49 56 A A < - 0 0 2 -3,-1.7 -17,-2.3 21,-0.2 2,-0.4 -0.501 37.7-156.1 -72.9 145.9 23.9 66.4 50.2 50 57 A S E +ce 32 72A 32 21,-2.7 23,-2.5 -19,-0.2 2,-0.6 -0.952 15.2 179.8-128.5 113.0 26.4 63.7 49.3 51 58 A I E +ce 33 73A 0 -19,-2.9 -17,-2.8 -2,-0.4 2,-0.5 -0.963 14.6 177.7-113.0 108.6 25.7 61.3 46.5 52 59 A R E +c 34 0A 97 21,-2.7 2,-0.8 -2,-0.6 23,-0.3 -0.921 17.7 174.5-126.1 106.4 28.7 59.0 46.3 53 60 A S E +c 35 0A 0 -19,-3.1 -17,-1.5 -2,-0.5 -46,-0.1 -0.730 46.5 108.8-112.4 79.0 28.8 56.2 43.8 54 61 A D S S+ 0 0 26 -2,-0.8 -1,-0.2 2,-0.2 3,-0.1 0.412 83.7 27.9-129.1 -13.1 32.3 54.8 44.3 55 62 A E S S+ 0 0 56 1,-0.7 23,-0.5 -3,-0.3 2,-0.3 0.472 128.6 21.5-114.0 -91.4 31.7 51.5 46.1 56 63 A G S S- 0 0 0 19,-1.8 -1,-0.7 21,-0.2 -2,-0.2 -0.577 96.6-129.8 -75.8 140.5 28.3 50.0 45.1 57 64 A M + 0 0 13 -2,-0.3 2,-0.1 -3,-0.1 -20,-0.1 -0.983 59.2 35.7-157.4 157.6 27.1 51.5 41.7 58 65 A P - 0 0 28 0, 0.0 41,-2.7 0, 0.0 42,-1.9 0.531 52.1-167.7 -86.9 164.6 25.2 52.8 39.9 59 66 A I E -df 37 100A 0 -23,-2.1 -21,-2.2 40,-0.2 2,-0.4 -0.990 10.9-169.2-112.5 120.5 23.1 55.3 41.9 60 67 A F E -df 38 101A 41 40,-2.9 42,-3.3 -2,-0.5 2,-0.5 -0.953 14.3-171.2-114.4 145.3 20.1 56.6 40.1 61 68 A V E -df 39 102A 0 -23,-2.9 -21,-2.7 -2,-0.4 42,-0.2 -0.984 24.5-139.1-131.6 115.6 17.7 59.5 41.0 62 69 A G > - 0 0 0 40,-2.1 3,-1.2 41,-0.8 -22,-0.2 0.096 34.7 -62.6 -72.4 174.2 14.6 59.8 38.8 63 70 A D T 3 S+ 0 0 60 1,-0.2 42,-2.4 -23,-0.1 -21,-0.2 -0.305 114.4 7.8 -62.0 140.0 12.9 62.7 37.3 64 71 A R T 3 S+ 0 0 93 -23,-3.3 -1,-0.2 1,-0.2 2,-0.2 0.693 95.0 133.0 64.2 26.0 11.3 65.4 39.6 65 72 A S < - 0 0 1 -3,-1.2 -21,-1.2 -24,-0.3 2,-0.4 -0.533 44.9-141.1 -96.3 170.8 12.8 63.9 42.7 66 73 A N E -op 44 107C 1 40,-2.4 42,-2.4 -23,-0.2 2,-0.5 -0.980 12.0-162.1-142.0 139.7 14.7 65.9 45.4 67 74 A V E -op 45 108C 0 -23,-2.8 -21,-2.7 -2,-0.4 -18,-0.2 -0.963 31.2-153.9-120.2 96.9 17.8 65.1 47.5 68 75 A Q > - 0 0 13 40,-2.6 3,-2.2 -2,-0.5 43,-0.1 0.001 32.9 -50.1 -78.4-177.4 17.6 67.6 50.4 69 76 A D T 3 S+ 0 0 62 1,-0.3 42,-2.3 41,-0.1 -21,-0.2 -0.188 121.6 0.1 -62.1 127.5 20.1 69.1 52.7 70 77 A G T 3 S+ 0 0 27 -23,-1.0 -1,-0.3 1,-0.2 -21,-0.2 0.556 88.7 149.3 78.4 3.5 22.6 66.7 54.3 71 78 A V < - 0 0 0 -3,-2.2 -21,-2.7 37,-0.2 2,-0.4 -0.514 32.2-152.8 -69.0 144.0 21.1 63.6 52.6 72 79 A V E -eg 50 113A 52 40,-1.6 42,-1.9 -23,-0.2 2,-0.4 -0.978 14.4-174.5-118.5 138.8 23.5 60.8 51.9 73 80 A L E +eg 51 114A 0 -23,-2.5 -21,-2.7 -2,-0.4 2,-0.3 -0.995 27.4 137.2-122.9 122.1 23.3 58.2 49.1 74 81 A H E - g 0 115A 16 40,-1.1 42,-2.8 -2,-0.4 2,-0.3 -0.916 30.0-150.0-151.9 171.6 26.0 55.5 49.1 75 82 A A E - g 0 116A 0 -23,-0.3 -19,-1.8 -2,-0.3 -21,-0.1 -0.999 20.5-100.1-155.8 153.6 26.1 51.7 48.6 76 83 A L - 0 0 48 40,-1.3 -19,-0.1 -2,-0.3 -21,-0.1 -0.363 64.7 -72.4 -66.1 152.5 27.7 48.4 49.5 77 84 A E - 0 0 47 -21,-0.2 -21,-0.2 1,-0.2 -1,-0.2 -0.113 40.0-170.9 -51.7 132.8 30.2 46.9 47.1 78 85 A T S S+ 0 0 4 -23,-0.5 8,-1.7 1,-0.2 2,-0.4 0.374 72.1 59.8-104.3 -3.3 28.5 45.5 44.0 79 86 A I B S-T 85 0D 50 6,-0.3 -1,-0.2 -24,-0.1 5,-0.1 -0.986 72.4-155.6-132.3 122.5 31.7 43.9 42.7 80 87 A N > - 0 0 33 4,-4.0 3,-2.7 -2,-0.4 2,-1.7 -0.309 39.6 -68.9 -94.4 175.8 33.7 41.2 44.6 81 88 A E T 3 S+ 0 0 182 1,-0.3 -1,-0.1 2,-0.2 -69,-0.1 -0.380 131.6 34.6 -72.4 90.5 37.3 39.9 44.6 82 89 A E T 3 S- 0 0 190 -2,-1.7 -1,-0.3 2,-0.0 -2,-0.1 0.062 130.3 -90.1 142.5 2.0 37.5 38.2 41.2 83 90 A G S < S+ 0 0 45 -3,-2.7 -2,-0.2 1,-0.2 3,-0.0 0.606 75.2 161.8 76.1 11.4 35.2 40.9 39.9 84 91 A E - 0 0 42 -4,-0.2 -4,-4.0 -5,-0.1 -1,-0.2 -0.465 44.8-118.8 -67.5 123.6 32.1 38.8 40.8 85 92 A P B -T 79 0D 73 0, 0.0 2,-1.1 0, 0.0 -6,-0.3 -0.400 22.1-132.8 -56.5 131.7 29.0 40.9 40.9 86 93 A I > - 0 0 45 -8,-1.7 3,-1.7 1,-0.2 4,-0.1 -0.820 22.0-169.7 -94.2 95.2 27.7 40.6 44.4 87 94 A E G > S+ 0 0 105 -2,-1.1 3,-1.1 1,-0.3 -1,-0.2 0.728 80.1 63.3 -60.5 -26.2 24.0 40.0 43.7 88 95 A D G 3 S+ 0 0 145 1,-0.2 -1,-0.3 -3,-0.1 -10,-0.1 0.713 105.5 48.4 -69.6 -23.1 22.8 40.4 47.2 89 96 A N G < S+ 0 0 26 -3,-1.7 2,-0.4 -12,-0.1 -1,-0.2 0.210 98.3 83.6-100.8 12.7 24.0 44.0 47.0 90 97 A I < - 0 0 29 -3,-1.1 2,-0.4 27,-0.1 9,-0.2 -0.951 62.7-153.8-121.6 134.5 22.3 44.8 43.6 91 98 A V E -U 98 0E 11 7,-3.4 7,-2.7 -2,-0.4 2,-0.5 -0.810 9.9-139.7-109.0 140.3 18.7 45.8 43.3 92 99 A E E +U 97 0E 91 -2,-0.4 2,-0.4 5,-0.2 5,-0.2 -0.929 24.2 170.9-101.2 122.9 16.6 45.2 40.1 93 100 A V E > S-U 96 0E 24 3,-2.6 3,-1.3 -2,-0.5 -2,-0.0 -0.978 72.2 -19.0-137.8 119.5 14.2 47.9 38.8 94 101 A D T 3 S- 0 0 145 -2,-0.4 3,-0.1 1,-0.3 -1,-0.1 0.899 127.3 -52.2 51.2 49.8 12.4 47.6 35.5 95 102 A G T 3 S+ 0 0 65 1,-0.2 2,-0.3 0, 0.0 -1,-0.3 0.586 117.7 107.4 66.1 14.2 15.0 45.1 34.2 96 103 A K E < -U 93 0E 131 -3,-1.3 -3,-2.6 2,-0.0 2,-0.4 -0.883 66.1-123.3-123.5 150.4 18.0 47.2 35.1 97 104 A E E +U 92 0E 96 -2,-0.3 2,-0.3 -5,-0.2 -5,-0.2 -0.845 32.2 170.4-102.5 132.3 20.5 46.8 37.9 98 105 A Y E -U 91 0E 28 -7,-2.7 -7,-3.4 -2,-0.4 3,-0.2 -0.958 37.1-152.6-131.5 157.4 21.2 49.5 40.5 99 106 A A S S+ 0 0 0 -41,-2.7 19,-1.7 1,-0.4 2,-0.4 0.864 101.9 9.4 -85.2 -50.5 23.1 49.9 43.8 100 107 A V E S-fh 59 118A 0 -42,-1.9 -40,-2.9 17,-0.2 2,-0.5 -0.987 72.8-170.3-130.0 124.4 20.7 52.6 44.8 101 108 A Y E -fh 60 119A 17 17,-2.4 19,-2.5 -2,-0.4 2,-0.5 -0.976 3.8-177.7-114.2 115.4 17.5 53.3 42.8 102 109 A I E -fh 61 120A 0 -42,-3.3 -40,-2.1 -2,-0.5 19,-0.2 -0.983 22.9-146.3-106.2 125.3 15.5 56.5 43.7 103 110 A G > - 0 0 0 17,-2.4 -41,-0.8 -2,-0.5 3,-0.6 0.291 29.3 -65.4 -76.2-158.8 12.4 56.6 41.5 104 111 A N T 3 S+ 0 0 35 1,-0.2 19,-2.2 -42,-0.1 20,-0.3 -0.600 113.9 15.0 -94.1 151.8 10.5 59.6 40.0 105 112 A N T 3 S+ 0 0 37 -42,-2.4 2,-0.4 -2,-0.2 -1,-0.2 0.849 89.9 148.7 57.0 38.3 8.7 62.2 42.2 106 113 A V < - 0 0 0 -3,-0.6 -40,-2.4 17,-0.2 2,-0.6 -0.860 36.6-151.8-104.4 135.6 10.6 60.9 45.3 107 114 A S E -pq 66 125C 0 17,-2.1 19,-3.3 -2,-0.4 2,-0.8 -0.940 8.3-169.6-107.3 123.9 11.4 63.3 48.1 108 115 A L E -pq 67 126C 0 -42,-2.4 -40,-2.6 -2,-0.6 19,-0.2 -0.885 27.7-148.3-106.9 97.9 14.5 62.5 50.3 109 116 A A > - 0 0 0 17,-3.0 3,-2.3 -2,-0.8 20,-0.3 -0.176 35.4 -53.3 -73.8 167.6 14.0 65.0 53.1 110 117 A H T 3 S- 0 0 77 1,-0.3 19,-1.8 18,-0.2 -40,-0.2 -0.001 119.8 -2.0 -43.6 128.1 16.7 66.8 55.1 111 118 A Q T 3 S+ 0 0 115 -42,-2.3 -1,-0.3 1,-0.2 -41,-0.1 0.484 95.1 134.6 69.7 6.2 19.3 64.5 56.7 112 119 A S < - 0 0 1 -3,-2.3 -40,-1.6 -43,-0.2 2,-0.3 -0.264 40.0-151.1 -71.9 177.3 17.7 61.3 55.5 113 120 A Q E -gi 72 131A 65 17,-1.6 19,-1.9 -42,-0.2 2,-0.5 -0.988 15.6-167.3-153.4 138.7 19.9 58.5 54.0 114 121 A V E -gi 73 132A 0 -42,-1.9 -40,-1.1 -2,-0.3 2,-0.5 -0.993 17.3-172.0-130.3 110.5 19.3 55.8 51.5 115 122 A H E -gi 74 133A 27 17,-3.0 19,-1.1 -2,-0.5 20,-0.3 -0.964 28.3 -78.7-112.6 129.7 22.1 53.2 51.5 116 123 A G E S+g 75 0A 0 -42,-2.8 -40,-1.3 -2,-0.5 -16,-0.2 -0.261 105.9 59.8 -72.2 156.8 22.4 50.4 48.9 117 124 A P E S+ 0 0 9 0, 0.0 18,-0.9 0, 0.0 17,-0.7 0.289 95.0 117.7 -71.2 129.7 21.3 47.9 48.2 118 125 A A E -hi 100 135A 0 -19,-1.7 -17,-2.4 16,-0.2 2,-0.4 -0.971 41.8-164.9-161.3 149.6 18.1 49.9 48.1 119 126 A A E -hi 101 136A 8 16,-2.0 18,-2.9 -2,-0.3 2,-0.5 -0.995 5.4-164.3-136.4 142.5 15.2 51.0 45.9 120 127 A V E -hi 102 137A 0 -19,-2.5 -17,-2.4 -2,-0.4 18,-0.2 -0.974 22.1-135.7-125.6 118.6 12.6 53.7 46.6 121 128 A G > - 0 0 18 16,-3.0 3,-0.8 -2,-0.5 20,-0.2 -0.125 35.6 -71.9 -73.9 166.3 9.5 53.6 44.4 122 129 A D T 3 S+ 0 0 56 1,-0.2 18,-2.6 17,-0.1 19,-0.3 -0.055 109.8 16.7 -58.2 151.8 7.8 56.6 42.8 123 130 A D T 3 S+ 0 0 51 -19,-2.2 2,-0.4 1,-0.2 -1,-0.2 0.840 88.4 140.9 55.8 36.1 5.9 59.2 44.7 124 131 A T < - 0 0 0 -3,-0.8 -17,-2.1 -20,-0.3 2,-0.6 -0.819 44.5-144.4-107.6 141.2 7.3 58.2 48.1 125 132 A F E -qr 107 142C 6 16,-2.1 18,-2.8 -2,-0.4 2,-0.7 -0.945 6.8-163.1-100.6 124.4 8.2 60.7 50.8 126 133 A I E -qr 108 143C 0 -19,-3.3 -17,-3.0 -2,-0.6 -14,-0.2 -0.917 29.6-133.6-106.5 108.3 11.3 59.7 52.9 127 134 A G > - 0 0 0 16,-2.5 3,-2.3 -2,-0.7 19,-0.2 0.035 30.4 -66.0 -64.3 169.8 11.0 61.9 55.9 128 135 A M T 3 S+ 0 0 81 1,-0.3 18,-2.2 17,-0.1 -17,-0.2 -0.170 119.5 1.1 -52.7 129.3 13.5 64.0 57.7 129 136 A Q T 3 S+ 0 0 84 -19,-1.8 -1,-0.3 -20,-0.3 -17,-0.1 0.577 97.7 145.3 67.7 17.4 16.3 62.0 59.4 130 137 A A < - 0 0 3 -3,-2.3 -17,-1.6 -20,-0.2 2,-0.4 -0.217 36.6-143.7 -84.3 166.8 14.8 58.7 58.1 131 138 A F E -ij 113 148A 58 16,-1.8 18,-2.1 -19,-0.2 2,-0.4 -0.997 16.8-178.0-140.5 134.7 16.9 55.7 57.0 132 139 A V E +ij 114 149A 0 -19,-1.9 -17,-3.0 -2,-0.4 2,-0.3 -0.998 16.8 158.5-131.8 121.7 16.6 53.1 54.3 133 140 A F E -ij 115 150A 51 16,-2.5 18,-1.7 -2,-0.4 19,-0.3 -0.981 66.9 -5.8-148.3 133.6 19.1 50.3 53.9 134 141 A K E S+ 0 0 107 -19,-1.1 2,-0.3 -17,-0.7 -16,-0.2 0.880 108.6 113.0 49.4 45.9 19.0 46.8 52.3 135 142 A S E -i 118 0A 6 -18,-0.9 -16,-2.0 -20,-0.3 2,-0.5 -0.958 64.5-136.2-144.9 161.5 15.3 47.5 51.6 136 143 A K E -ik 119 153A 85 16,-2.3 18,-3.5 -2,-0.3 2,-0.5 -0.986 18.9-162.8-120.2 116.5 12.8 48.1 48.9 137 144 A V E -ik 120 154A 4 -18,-2.9 -16,-3.0 -2,-0.5 19,-0.1 -0.922 18.7-135.7-100.5 121.7 10.3 50.9 49.6 138 145 A G > - 0 0 11 16,-1.7 3,-0.5 -2,-0.5 -17,-0.4 0.046 30.0 -79.6 -69.0-175.0 7.3 50.7 47.3 139 146 A N T 3 S+ 0 0 62 1,-0.2 18,-2.4 -19,-0.1 19,-0.2 -0.409 109.4 25.4 -81.1 157.4 5.6 53.6 45.5 140 147 A N T 3 S+ 0 0 77 -18,-2.6 -1,-0.2 16,-0.2 38,-0.2 0.822 91.8 140.9 56.0 37.1 3.2 56.0 47.2 141 148 A C < - 0 0 0 -3,-0.5 -16,-2.1 -19,-0.3 2,-0.4 -0.597 41.7-149.3-103.4 165.1 4.8 55.3 50.6 142 149 A V E -rs 125 159C 8 16,-1.6 18,-2.4 -18,-0.2 2,-0.7 -0.972 6.0-168.5-134.7 121.1 5.6 57.6 53.5 143 150 A L E -rs 126 160C 0 -18,-2.8 -16,-2.5 -2,-0.4 -13,-0.1 -0.945 27.6-140.2-103.8 109.6 8.4 57.2 55.9 144 151 A E > - 0 0 26 16,-2.3 3,-2.1 -2,-0.7 19,-0.2 -0.228 42.1 -64.9 -63.1 164.6 7.7 59.6 58.7 145 152 A P T 3 S+ 0 0 31 0, 0.0 18,-1.3 0, 0.0 -16,-0.2 -0.158 123.1 9.0 -51.9 134.8 10.6 61.6 60.2 146 153 A R T 3 S+ 0 0 154 -18,-2.2 2,-0.1 16,-0.2 -17,-0.1 0.575 95.0 131.5 67.5 13.4 13.1 59.3 62.0 147 154 A S < - 0 0 1 -3,-2.1 -16,-1.8 -19,-0.2 2,-0.3 -0.428 39.3-158.1 -83.3 169.2 11.5 56.1 60.8 148 155 A A E -jl 131 165A 7 16,-2.6 18,-2.9 -18,-0.2 2,-0.4 -0.996 18.2-160.6-150.4 145.5 13.7 53.4 59.3 149 156 A A E +jl 132 166A 0 -18,-2.1 -16,-2.5 -2,-0.3 2,-0.4 -0.991 21.3 171.6-124.4 113.4 13.5 50.4 56.9 150 157 A I E -j 133 0A 52 16,-2.9 -16,-0.2 -2,-0.4 -15,-0.1 -0.974 66.0 -9.9-129.9 123.1 16.3 47.8 57.2 151 158 A G S S+ 0 0 50 -18,-1.7 2,-0.3 -2,-0.4 -16,-0.2 0.620 110.5 101.2 71.5 19.0 16.4 44.4 55.4 152 159 A V - 0 0 4 -19,-0.3 -16,-2.3 14,-0.2 2,-0.5 -0.795 69.1-123.2-132.2 170.6 12.8 44.6 54.4 153 160 A T E -k 136 0A 67 -2,-0.3 -16,-0.2 -18,-0.2 -3,-0.0 -0.955 23.2-153.4-111.8 119.9 10.3 45.3 51.5 154 161 A I E -k 137 0A 1 -18,-3.5 -16,-1.7 -2,-0.5 3,-0.1 -0.887 23.6-125.9 -95.9 117.9 7.7 48.0 52.3 155 162 A P > - 0 0 34 0, 0.0 3,-1.1 0, 0.0 -17,-0.1 -0.292 36.7 -81.1 -62.3 154.5 4.6 47.3 50.3 156 163 A D T 3 S+ 0 0 92 1,-0.2 -16,-0.2 -19,-0.1 -15,-0.1 -0.139 111.5 16.8 -53.4 144.5 3.1 50.0 48.0 157 164 A G T 3 S+ 0 0 19 -18,-2.4 21,-3.2 1,-0.2 2,-0.3 0.721 94.2 123.6 63.8 24.6 1.0 52.7 49.8 158 165 A R B < -V 177 0F 46 -3,-1.1 -16,-1.6 19,-0.3 2,-0.3 -0.757 45.2-147.6-108.1 163.2 2.1 52.0 53.4 159 166 A Y E -s 142 0C 51 17,-2.1 -16,-0.2 -2,-0.3 -18,-0.0 -0.892 7.6-139.9-127.7 156.8 3.6 54.4 55.9 160 167 A I E -s 143 0C 0 -18,-2.4 -16,-2.3 -2,-0.3 -13,-0.2 -0.929 30.2-122.0-114.0 113.2 6.1 54.0 58.7 161 168 A P > - 0 0 36 0, 0.0 3,-2.1 0, 0.0 14,-0.0 -0.157 44.2 -78.0 -50.7 143.9 5.2 56.0 61.9 162 169 A A T 3 S+ 0 0 58 1,-0.3 -16,-0.2 -15,-0.1 3,-0.1 -0.107 115.3 9.6 -46.4 131.0 7.8 58.5 63.2 163 170 A G T 3 S+ 0 0 44 -18,-1.3 2,-0.3 1,-0.2 -1,-0.3 0.237 91.1 135.7 83.3 -11.7 10.6 56.9 65.1 164 171 A M < - 0 0 80 -3,-2.1 -16,-2.6 -4,-0.1 2,-0.7 -0.517 42.0-154.7 -78.0 128.8 9.8 53.3 64.1 165 172 A V E -l 148 0A 82 -2,-0.3 2,-0.7 -18,-0.2 -16,-0.2 -0.885 8.7-160.6-104.0 107.0 12.7 51.1 63.1 166 173 A V E +l 149 0A 1 -18,-2.9 -16,-2.9 -2,-0.7 -14,-0.2 -0.807 27.7 152.1 -94.5 114.8 11.4 48.3 60.8 167 174 A T + 0 0 79 -2,-0.7 2,-0.4 -18,-0.2 -1,-0.1 0.410 52.9 64.4-121.0 -6.3 13.8 45.4 60.6 168 175 A S S > S- 0 0 43 1,-0.1 4,-2.2 -16,-0.0 3,-0.2 -0.971 70.8-133.6-127.0 147.7 11.6 42.3 59.9 169 176 A Q H > S+ 0 0 73 -2,-0.4 4,-2.0 1,-0.2 5,-0.1 0.802 107.4 60.1 -63.8 -29.0 9.4 41.4 57.0 170 177 A A H > S+ 0 0 67 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.927 108.1 44.9 -64.6 -42.8 6.5 40.5 59.4 171 178 A E H >4 S+ 0 0 91 -3,-0.2 3,-0.8 1,-0.2 -2,-0.2 0.909 112.3 50.4 -67.1 -43.3 6.5 44.0 60.7 172 179 A A H >< S+ 0 0 0 -4,-2.2 3,-1.3 1,-0.2 -1,-0.2 0.859 104.9 59.1 -65.3 -31.7 6.7 45.6 57.2 173 180 A D H 3< S+ 0 0 86 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.793 108.0 46.2 -65.2 -25.7 3.8 43.4 56.1 174 181 A K T << S+ 0 0 181 -3,-0.8 -1,-0.2 -4,-0.8 -2,-0.2 0.195 80.2 131.0-102.6 14.0 1.6 44.9 58.8 175 182 A L < - 0 0 10 -3,-1.3 -15,-0.1 1,-0.1 -3,-0.0 -0.405 64.6-101.4 -65.7 152.0 2.5 48.6 58.3 176 183 A P - 0 0 48 0, 0.0 -17,-2.1 0, 0.0 2,-0.3 -0.179 36.6-112.5 -68.1 157.5 -0.6 50.9 58.1 177 184 A E B -V 158 0F 122 -19,-0.3 2,-0.3 -3,-0.1 -19,-0.3 -0.681 22.0-111.8 -95.8 150.0 -1.9 52.2 54.8 178 185 A V + 0 0 41 -21,-3.2 2,-0.3 -2,-0.3 -1,-0.0 -0.620 43.5 173.4 -73.6 130.3 -1.9 55.7 53.4 179 186 A T > - 0 0 70 -2,-0.3 3,-1.4 1,-0.0 6,-0.2 -0.885 47.1 -98.3-128.1 169.9 -5.4 57.0 53.2 180 187 A D T 3 S+ 0 0 119 -2,-0.3 5,-0.1 1,-0.3 6,-0.1 0.850 122.7 49.1 -57.4 -36.6 -6.8 60.5 52.4 181 188 A D T 3 S+ 0 0 141 4,-0.1 -1,-0.3 3,-0.1 2,-0.1 0.584 82.8 115.0 -81.4 -7.2 -7.2 61.5 56.0 182 189 A Y S X S- 0 0 19 -3,-1.4 3,-1.9 1,-0.1 4,-0.3 -0.394 76.9-121.3 -63.3 139.2 -3.7 60.3 57.0 183 190 A A T 3 S+ 0 0 87 1,-0.3 3,-0.3 2,-0.1 -1,-0.1 0.804 109.3 37.2 -55.5 -35.4 -1.6 63.3 58.1 184 191 A Y T >> S+ 0 0 65 1,-0.2 3,-0.9 2,-0.1 4,-0.6 0.216 82.4 110.8-102.8 16.6 1.1 62.9 55.5 185 192 A S T <4 S+ 0 0 30 -3,-1.9 4,-0.2 1,-0.3 -1,-0.2 0.831 89.8 30.2 -60.0 -35.8 -1.2 61.7 52.6 186 193 A H T 3> S+ 0 0 95 -3,-0.3 4,-1.4 -4,-0.3 -1,-0.3 0.315 95.5 96.5-102.2 3.0 -0.7 64.9 50.6 187 194 A T H <> S+ 0 0 38 -3,-0.9 4,-2.6 1,-0.2 5,-0.2 0.933 80.1 49.5 -62.9 -48.0 2.9 65.8 51.7 188 195 A N H X S+ 0 0 8 -4,-0.6 4,-2.7 1,-0.2 5,-0.3 0.900 109.0 50.3 -63.9 -42.1 4.9 64.3 48.9 189 196 A E H > S+ 0 0 112 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.904 113.4 47.2 -65.2 -33.0 2.9 65.9 46.0 190 197 A A H X S+ 0 0 52 -4,-1.4 4,-2.7 2,-0.2 5,-0.2 0.918 112.8 49.6 -69.2 -46.9 3.3 69.3 47.7 191 198 A V H X S+ 0 0 26 -4,-2.6 4,-2.8 2,-0.2 5,-0.2 0.906 110.8 48.4 -57.3 -43.6 7.0 68.7 48.3 192 199 A V H X S+ 0 0 16 -4,-2.7 4,-2.9 -5,-0.2 5,-0.3 0.960 110.9 51.6 -66.9 -40.5 7.6 67.7 44.7 193 200 A Y H X S+ 0 0 148 -4,-2.1 4,-2.0 -5,-0.3 -2,-0.2 0.961 113.8 44.1 -59.4 -47.6 5.7 70.7 43.4 194 201 A V H X S+ 0 0 66 -4,-2.7 4,-2.6 1,-0.2 -1,-0.2 0.947 114.8 48.7 -60.2 -50.3 7.8 73.0 45.6 195 202 A N H X S+ 0 0 15 -4,-2.8 4,-2.6 -5,-0.2 -1,-0.2 0.899 107.1 53.1 -67.9 -32.9 11.1 71.3 44.8 196 203 A V H X S+ 0 0 35 -4,-2.9 4,-1.8 -5,-0.2 -1,-0.2 0.944 112.7 47.0 -67.0 -37.1 10.6 71.3 41.0 197 204 A H H X S+ 0 0 111 -4,-2.0 4,-2.5 -5,-0.3 -2,-0.2 0.892 111.4 50.9 -69.3 -35.7 10.0 75.0 41.2 198 205 A L H X S+ 0 0 72 -4,-2.6 4,-3.4 2,-0.2 5,-0.3 0.927 106.4 54.2 -66.8 -41.8 13.0 75.5 43.5 199 206 A A H X S+ 0 0 0 -4,-2.6 4,-2.5 1,-0.2 -1,-0.2 0.953 112.1 45.0 -56.2 -46.8 15.3 73.6 41.0 200 207 A E H X S+ 0 0 90 -4,-1.8 4,-1.3 2,-0.2 -2,-0.2 0.935 113.9 48.3 -66.9 -42.7 14.2 76.0 38.2 201 208 A G H >< S+ 0 0 34 -4,-2.5 3,-0.5 1,-0.2 4,-0.2 0.943 114.6 46.1 -61.9 -44.2 14.5 79.2 40.4 202 209 A Y H >< S+ 0 0 97 -4,-3.4 3,-1.9 1,-0.2 4,-0.4 0.911 106.9 58.0 -66.0 -35.0 18.0 78.0 41.5 203 210 A K H >< S+ 0 0 64 -4,-2.5 3,-1.1 -5,-0.3 -1,-0.2 0.835 100.0 59.5 -61.7 -32.0 19.0 77.2 37.9 204 211 A E T << S+ 0 0 138 -4,-1.3 -1,-0.3 -3,-0.5 -2,-0.2 0.467 101.7 55.1 -76.9 1.6 18.2 80.8 37.0 205 212 A T T < 0 0 98 -3,-1.9 -1,-0.2 -4,-0.2 -2,-0.2 0.419 360.0 360.0-108.2 -7.6 20.9 82.0 39.5 206 213 A S < 0 0 130 -3,-1.1 -2,-0.1 -4,-0.4 -1,-0.1 0.359 360.0 360.0-104.1 360.0 23.7 79.9 38.1