==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 15-JUN-99 1QRL . COMPND 2 MOLECULE: CARBONIC ANHYDRASE; . SOURCE 2 ORGANISM_SCIENTIFIC: METHANOSARCINA THERMOPHILA; . AUTHOR T.M.IVERSON,B.E.ALBER,C.KISKER,J.G.FERRY,D.C.REES . 214 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10483.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 165 77.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 67 31.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 4.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 27 12.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 26 12.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 19 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 11 4 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A M > 0 0 207 0, 0.0 2,-1.3 0, 0.0 3,-0.7 0.000 360.0 360.0 360.0 136.6 44.2 80.5 60.4 2 1 A Q T 3 - 0 0 154 1,-0.3 0, 0.0 2,-0.1 0, 0.0 0.398 360.0-122.2 53.5 -8.9 47.0 81.0 57.8 3 2 A E T 3 - 0 0 140 -2,-1.3 -1,-0.3 1,-0.1 0, 0.0 0.916 17.7-135.9 37.3 73.2 44.3 79.7 55.4 4 3 A I < - 0 0 131 -3,-0.7 2,-0.2 2,-0.1 -1,-0.1 0.680 68.9 -48.0 -21.5 -52.7 46.4 76.6 54.2 5 4 A T - 0 0 97 2,-0.0 0, 0.0 0, 0.0 0, 0.0 -0.539 68.7 -83.6-152.0-130.8 45.4 77.5 50.6 6 5 A V - 0 0 120 -2,-0.2 -2,-0.1 2,-0.0 -3,-0.0 0.319 52.6-125.2-140.3 8.8 42.0 78.2 49.1 7 6 A D - 0 0 119 1,-0.1 2,-0.3 0, 0.0 -3,-0.0 0.972 30.2-164.9 41.5 77.3 40.8 74.6 48.5 8 7 A E + 0 0 94 2,-0.0 2,-0.3 0, 0.0 -1,-0.1 -0.639 26.6 127.1 -89.1 140.7 39.9 74.5 44.8 9 8 A F - 0 0 148 -2,-0.3 2,-0.4 0, 0.0 0, 0.0 -0.936 53.8-105.4-177.6 165.2 37.8 71.6 43.5 10 9 A S - 0 0 67 -2,-0.3 3,-0.0 1,-0.1 -2,-0.0 -0.846 15.2-153.9-107.2 139.5 34.7 70.4 41.6 11 10 A N S S+ 0 0 32 -2,-0.4 30,-3.2 1,-0.1 2,-0.6 0.497 86.8 64.4 -87.3 -6.9 31.8 69.1 43.6 12 11 A I E S+a 41 0A 61 28,-0.2 2,-0.3 30,-0.1 30,-0.2 -0.968 78.4 150.9-119.6 110.8 30.6 66.9 40.6 13 12 A R E -a 42 0A 130 28,-2.3 30,-3.3 -2,-0.6 2,-0.2 -0.893 46.6 -99.0-142.5 163.0 33.3 64.3 40.0 14 13 A E - 0 0 49 -2,-0.3 12,-0.2 28,-0.2 48,-0.1 -0.513 44.3-108.7 -78.7 158.8 34.3 60.9 38.7 15 14 A N - 0 0 6 10,-1.4 -1,-0.1 -2,-0.2 2,-0.1 -0.393 42.1 -97.3 -80.5 161.5 34.8 58.1 41.2 16 15 A P - 0 0 72 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.378 35.0 -98.2 -81.7 158.2 38.3 56.8 41.7 17 16 A V + 0 0 100 -2,-0.1 45,-0.0 5,-0.1 6,-0.0 -0.623 56.7 159.1 -72.2 130.3 40.0 53.8 40.2 18 17 A T B > -M 21 0B 28 3,-1.2 3,-1.9 -2,-0.4 5,-0.0 -0.912 58.6 -88.8-138.3 178.7 39.8 50.9 42.6 19 18 A P T 3 S+ 0 0 86 0, 0.0 -2,-0.0 0, 0.0 -1,-0.0 0.798 130.7 41.5 -64.1 -25.8 40.1 47.1 42.3 20 19 A W T 3 S+ 0 0 64 1,-0.2 66,-0.1 69,-0.1 -3,-0.0 0.340 116.6 50.0-102.7 5.9 36.3 47.0 41.7 21 20 A N B < +M 18 0B 9 -3,-1.9 -3,-1.2 1,-0.1 -1,-0.2 -0.604 53.2 163.8-147.0 79.1 36.2 50.0 39.3 22 21 A P S S+ 0 0 94 0, 0.0 -1,-0.1 0, 0.0 -5,-0.1 0.786 75.3 48.4 -66.9 -31.1 38.8 49.8 36.5 23 22 A E S S- 0 0 143 -7,-0.1 -8,-0.1 -5,-0.0 -6,-0.0 -0.916 85.1-137.6-119.8 108.2 37.0 52.5 34.5 24 23 A P - 0 0 55 0, 0.0 2,-0.3 0, 0.0 -7,-0.1 -0.231 17.3-153.7 -59.5 147.6 36.0 55.7 36.3 25 24 A S - 0 0 37 -9,-0.1 -10,-1.4 -12,-0.1 18,-0.2 -0.902 4.0-146.2-127.0 146.6 32.6 57.2 35.6 26 25 A A - 0 0 64 -2,-0.3 19,-0.2 -12,-0.2 -12,-0.2 -0.819 37.4 -90.5-111.1 148.6 31.3 60.7 35.8 27 26 A P - 0 0 21 0, 0.0 2,-0.6 0, 0.0 19,-0.2 -0.375 28.1-140.9 -55.3 145.3 27.7 61.6 36.8 28 27 A V E +b 46 0A 98 17,-3.0 19,-2.8 2,-0.0 2,-0.5 -0.964 30.2 179.6-111.0 106.7 25.1 61.9 34.0 29 28 A I E -b 47 0A 46 -2,-0.6 19,-0.2 17,-0.2 20,-0.1 -0.963 29.2-120.7-119.0 123.4 23.0 64.9 35.1 30 29 A D > - 0 0 54 17,-2.3 3,-2.3 -2,-0.5 21,-0.1 -0.198 25.2-122.2 -57.5 138.3 20.0 66.2 33.2 31 30 A P T 3 S+ 0 0 108 0, 0.0 -1,-0.1 0, 0.0 18,-0.1 0.716 111.5 56.7 -52.0 -27.2 20.5 69.9 32.2 32 31 A T T 3 S+ 0 0 49 2,-0.1 2,-0.2 179,-0.0 179,-0.1 0.424 86.2 96.6 -89.5 -3.1 17.2 70.8 34.1 33 32 A A < - 0 0 2 -3,-2.3 2,-0.5 17,-0.2 19,-0.2 -0.584 68.4-140.2 -81.3 155.9 18.4 69.3 37.4 34 33 A Y E -n 52 0C 19 17,-3.0 19,-2.7 -2,-0.2 2,-0.6 -0.974 13.7-169.5-114.4 122.8 20.0 71.7 39.9 35 34 A I E -n 53 0C 23 -2,-0.5 19,-0.2 17,-0.2 17,-0.1 -0.947 25.0-129.8-107.9 116.6 23.0 70.6 41.9 36 35 A D > - 0 0 15 17,-2.6 3,-2.1 -2,-0.6 20,-0.1 -0.238 17.9-122.0 -60.2 149.0 23.8 73.0 44.8 37 36 A P T 3 S+ 0 0 80 0, 0.0 -1,-0.2 0, 0.0 17,-0.1 0.825 113.7 52.9 -62.5 -25.4 27.5 74.1 44.8 38 37 A Q T 3 S+ 0 0 126 2,-0.1 18,-2.2 -27,-0.0 2,-0.2 0.233 92.8 89.3 -99.6 16.8 27.8 72.7 48.4 39 38 A A S < S- 0 0 3 -3,-2.1 2,-0.4 16,-0.3 19,-0.2 -0.677 70.9-138.7 -96.8 163.8 26.3 69.3 47.5 40 39 A S E - c 0 58A 26 17,-2.5 19,-3.0 -2,-0.2 2,-0.5 -0.993 19.2-179.7-123.3 135.1 28.7 66.5 46.3 41 40 A V E +ac 12 59A 0 -30,-3.2 -28,-2.3 -2,-0.4 2,-0.4 -0.974 13.1 178.8-138.0 113.6 27.9 64.1 43.5 42 41 A I E -ac 13 60A 13 17,-2.9 19,-3.0 -2,-0.5 -28,-0.2 -0.963 35.2 -26.6-125.5 136.6 30.5 61.5 42.7 43 42 A G E S+ c 0 61A 0 -30,-3.3 2,-1.7 -2,-0.4 19,-0.2 -0.448 107.1 12.4 81.7-145.8 30.9 58.7 40.3 44 43 A E S S+ 0 0 70 17,-1.5 23,-2.2 -2,-0.2 2,-0.4 -0.575 83.5 140.8 -85.0 84.5 28.4 56.5 38.4 45 44 A V E - d 0 67A 2 -2,-1.7 -17,-3.0 21,-0.2 2,-0.5 -0.996 39.4-156.6-125.9 139.9 25.3 58.4 39.2 46 45 A T E -bd 28 68A 50 21,-2.2 23,-2.9 -2,-0.4 2,-0.5 -0.983 11.0-169.9-117.1 125.8 22.3 59.2 37.0 47 46 A I E -bd 29 69A 3 -19,-2.8 -17,-2.3 -2,-0.5 23,-0.2 -0.975 15.1-141.0-117.5 126.1 20.2 62.3 38.0 48 47 A G > - 0 0 8 21,-2.2 3,-1.0 -2,-0.5 23,-0.1 0.135 33.2 -65.5 -77.9 176.2 16.9 62.9 36.3 49 48 A A T 3 S+ 0 0 15 1,-0.2 23,-3.4 -16,-0.1 24,-0.3 -0.332 111.8 7.0 -67.3 148.6 15.1 66.0 35.0 50 49 A N T 3 S+ 0 0 48 1,-0.2 2,-0.3 21,-0.2 -1,-0.2 0.746 87.1 150.7 58.9 23.7 13.9 68.7 37.3 51 50 A V < - 0 0 0 -3,-1.0 -17,-3.0 21,-0.1 2,-0.5 -0.688 36.3-147.3 -86.1 143.2 15.6 67.2 40.4 52 51 A M E -no 34 74C 3 21,-1.2 23,-2.5 -2,-0.3 2,-0.6 -0.938 9.6-168.3-108.2 123.0 16.8 69.5 43.1 53 52 A V E -no 35 75C 0 -19,-2.7 -17,-2.6 -2,-0.5 23,-0.2 -0.971 19.4-151.1-108.9 115.5 19.9 68.5 45.1 54 53 A S > - 0 0 14 21,-2.6 3,-1.6 -2,-0.6 24,-0.2 -0.193 29.6 -65.1 -84.5 171.5 20.3 70.7 48.2 55 54 A P T 3 S+ 0 0 34 0, 0.0 23,-1.1 0, 0.0 -16,-0.3 -0.237 115.7 12.9 -54.5 139.0 23.3 71.9 50.2 56 55 A M T 3 S+ 0 0 114 -18,-2.2 -17,-0.2 1,-0.3 2,-0.1 0.398 87.0 138.1 76.5 0.5 25.4 69.3 52.0 57 56 A A < - 0 0 2 -3,-1.6 -17,-2.5 21,-0.2 2,-0.5 -0.499 38.4-156.4 -71.1 151.1 23.8 66.3 50.3 58 57 A S E -ce 40 80A 32 21,-3.1 23,-2.4 -19,-0.2 2,-0.6 -0.960 14.9-179.5-134.4 113.2 26.3 63.7 49.3 59 58 A I E +ce 41 81A 0 -19,-3.0 -17,-2.9 -2,-0.5 2,-0.5 -0.962 14.6 177.3-110.8 109.9 25.6 61.3 46.5 60 59 A R E +c 42 0A 98 21,-2.9 2,-0.7 -2,-0.6 23,-0.3 -0.949 18.7 175.4-128.9 110.4 28.5 58.9 46.2 61 60 A S E +c 43 0A 0 -19,-3.0 -17,-1.5 -2,-0.5 -46,-0.2 -0.767 46.3 111.5-110.7 77.6 28.7 56.0 43.7 62 61 A D S S+ 0 0 25 -2,-0.7 -1,-0.2 2,-0.2 3,-0.1 0.382 84.4 24.8-128.9 0.1 32.2 54.8 44.3 63 62 A E S S+ 0 0 58 1,-0.9 23,-0.5 -3,-0.2 21,-0.2 0.416 127.8 25.7-128.0 -93.1 31.6 51.4 45.9 64 63 A G S S- 0 0 0 19,-1.9 -1,-0.9 21,-0.2 19,-0.2 -0.485 95.9-129.9 -71.8 140.8 28.2 50.0 45.0 65 64 A M + 0 0 17 -2,-0.2 2,-0.1 -3,-0.1 -20,-0.1 -0.983 60.6 34.7-153.7 156.7 27.0 51.4 41.6 66 65 A P - 0 0 27 0, 0.0 41,-2.7 0, 0.0 42,-2.1 0.514 52.8-168.7 -86.9 163.8 25.0 52.7 39.9 67 66 A I E -df 45 108A 0 -23,-2.2 -21,-2.2 40,-0.2 2,-0.4 -0.987 11.8-170.8-114.6 117.9 23.0 55.2 41.9 68 67 A F E -df 46 109A 41 40,-2.8 42,-2.5 -2,-0.5 2,-0.5 -0.918 14.1-169.8-112.6 141.1 19.9 56.6 40.0 69 68 A V E -df 47 110A 0 -23,-2.9 -21,-2.2 -2,-0.4 42,-0.2 -0.995 24.9-136.2-132.2 115.4 17.6 59.4 41.0 70 69 A G > - 0 0 0 40,-1.6 3,-1.1 41,-0.8 -22,-0.3 0.024 35.1 -66.1 -67.3 174.5 14.4 59.7 38.9 71 70 A D T 3 S+ 0 0 58 1,-0.2 42,-2.1 -23,-0.1 43,-0.2 -0.419 114.2 8.4 -65.9 145.2 12.8 62.7 37.4 72 71 A R T 3 S+ 0 0 93 -23,-3.4 -1,-0.2 1,-0.2 132,-0.2 0.676 95.2 130.8 58.3 28.1 11.2 65.3 39.6 73 72 A S < - 0 0 1 -3,-1.1 -21,-1.2 -24,-0.3 2,-0.4 -0.544 45.8-142.6-101.1 168.9 12.7 63.8 42.8 74 73 A N E -op 52 115C 0 40,-2.3 42,-2.3 -23,-0.2 2,-0.6 -0.992 11.5-158.3-141.7 144.9 14.6 65.8 45.4 75 74 A V E -op 53 116C 0 -23,-2.5 -21,-2.6 -2,-0.4 -18,-0.2 -0.961 31.0-151.0-122.5 100.0 17.6 65.1 47.6 76 75 A Q > - 0 0 10 40,-2.9 3,-2.0 -2,-0.6 43,-0.1 0.082 33.4 -52.2 -78.3-178.3 17.4 67.5 50.5 77 76 A D T 3 S+ 0 0 58 1,-0.3 42,-2.5 41,-0.1 -21,-0.2 -0.271 121.7 1.3 -62.3 132.8 20.0 69.0 52.7 78 77 A G T 3 S+ 0 0 28 -23,-1.1 -1,-0.3 1,-0.2 -21,-0.2 0.515 89.1 149.6 75.1 5.8 22.5 66.6 54.3 79 78 A V < - 0 0 0 -3,-2.0 -21,-3.1 37,-0.1 2,-0.5 -0.479 32.1-153.2 -72.6 136.3 20.9 63.5 52.6 80 79 A V E -eg 58 121A 50 40,-1.6 42,-1.7 -23,-0.2 2,-0.4 -0.976 14.7-175.3-115.0 136.7 23.4 60.8 51.9 81 80 A L E +eg 59 122A 0 -23,-2.4 -21,-2.9 -2,-0.5 2,-0.3 -0.989 27.6 135.0-121.8 124.5 23.2 58.2 49.1 82 81 A H E - g 0 123A 15 40,-1.1 42,-2.8 -2,-0.4 2,-0.3 -0.924 30.5-150.0-156.7 167.4 25.9 55.5 49.1 83 82 A A E - g 0 124A 0 -23,-0.3 -19,-1.9 -2,-0.3 -21,-0.1 -0.996 20.7 -98.1-154.6 158.8 26.0 51.7 48.7 84 83 A L - 0 0 51 40,-1.3 -19,-0.1 -2,-0.3 -21,-0.1 -0.311 65.9 -72.6 -65.8 155.6 27.7 48.3 49.5 85 84 A E - 0 0 51 -21,-0.2 -21,-0.2 1,-0.1 -1,-0.2 -0.173 43.8-173.1 -55.7 127.8 30.1 46.9 47.0 86 85 A T + 0 0 8 -23,-0.5 8,-1.9 -3,-0.1 2,-0.4 0.489 64.4 57.9-102.6 -9.1 28.2 45.5 44.0 87 86 A I B -T 93 0D 40 6,-0.2 5,-0.2 -24,-0.1 -1,-0.1 -0.979 65.1-152.8-131.4 143.4 31.2 43.9 42.3 88 87 A N - 0 0 74 4,-2.1 6,-0.1 -2,-0.4 -2,-0.1 0.059 26.4-111.1 -89.3-158.1 33.7 41.3 43.3 89 88 A E S S+ 0 0 96 3,-0.1 3,-0.1 1,-0.0 -69,-0.1 -0.511 109.4 48.9-138.4 63.2 37.3 40.5 42.3 90 89 A E S S- 0 0 189 1,-0.9 2,-0.3 2,-0.0 -1,-0.0 0.040 137.1 -32.7-176.8 -5.6 37.0 37.3 40.4 91 90 A G S S- 0 0 45 1,-0.1 -1,-0.9 0, 0.0 -3,-0.1 -0.930 78.8 -90.1 161.0-158.8 34.2 38.6 38.3 92 91 A E S S+ 0 0 43 -2,-0.3 -4,-2.1 -5,-0.2 -1,-0.1 0.690 73.7 90.6-108.6 -98.6 31.5 41.1 39.0 93 92 A P B +T 87 0D 77 0, 0.0 2,-0.7 0, 0.0 -6,-0.2 0.391 29.3 178.9 -10.9 107.7 28.0 40.5 40.4 94 93 A I > - 0 0 42 -8,-1.9 3,-2.7 1,-0.1 -7,-0.1 -0.782 20.7-172.5-109.8 74.7 27.6 40.6 44.2 95 94 A E G > S+ 0 0 105 -2,-0.7 3,-1.3 1,-0.3 -1,-0.1 0.645 72.6 63.2 -47.0 -32.1 23.9 39.9 43.6 96 95 A D G 3 S+ 0 0 149 1,-0.3 -1,-0.3 -3,-0.1 -10,-0.1 0.677 106.0 47.7 -69.9 -20.1 22.8 40.3 47.2 97 96 A N G < S+ 0 0 28 -3,-2.7 2,-0.4 -12,-0.1 -1,-0.3 0.122 98.5 86.6-102.9 14.0 23.9 44.0 47.0 98 97 A I < - 0 0 29 -3,-1.3 2,-0.3 27,-0.1 9,-0.2 -0.967 61.7-154.8-121.7 131.8 22.2 44.7 43.7 99 98 A V E -U 106 0E 14 7,-2.8 7,-2.7 -2,-0.4 2,-0.4 -0.797 8.4-146.5-105.7 147.2 18.6 45.8 43.4 100 99 A E E +U 105 0E 83 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.963 22.4 166.6-121.4 124.5 16.6 45.2 40.2 101 100 A V E > S-U 104 0E 27 3,-2.1 3,-1.4 -2,-0.4 -2,-0.0 -0.965 72.0 -12.2-143.2 122.8 13.9 47.6 38.9 102 101 A D T 3 S- 0 0 135 -2,-0.3 3,-0.1 1,-0.2 -1,-0.0 0.912 128.1 -54.0 47.8 48.9 12.3 47.5 35.4 103 102 A G T 3 S+ 0 0 69 1,-0.2 2,-0.3 0, 0.0 -1,-0.2 0.594 116.3 105.5 67.0 14.9 14.9 45.0 34.2 104 103 A K E < -U 101 0E 125 -3,-1.4 -3,-2.1 2,-0.0 2,-0.3 -0.959 64.6-127.5-128.4 150.2 17.9 47.1 35.1 105 104 A E E +U 100 0E 93 -2,-0.3 2,-0.3 -5,-0.2 -5,-0.2 -0.718 30.7 168.9 -99.7 139.9 20.4 46.7 38.0 106 105 A Y E -U 99 0E 21 -7,-2.7 -7,-2.8 -2,-0.3 3,-0.2 -0.984 39.0-145.2-142.6 156.2 21.3 49.4 40.5 107 106 A A S S+ 0 0 0 -41,-2.7 19,-1.6 1,-0.4 2,-0.4 0.855 102.3 9.6 -82.6 -44.4 23.1 49.8 43.7 108 107 A V E S-fh 67 126A 0 -42,-2.1 -40,-2.8 17,-0.2 2,-0.5 -0.954 71.4-169.1-131.0 131.7 20.6 52.5 44.7 109 108 A Y E -fh 68 127A 17 17,-2.6 19,-2.4 -2,-0.4 2,-0.6 -0.942 4.1-178.0-122.1 116.3 17.4 53.2 42.8 110 109 A I E -fh 69 128A 0 -42,-2.5 -40,-1.6 -2,-0.5 19,-0.2 -0.984 23.3-145.4-109.9 115.5 15.4 56.4 43.7 111 110 A G > - 0 0 0 17,-2.3 -41,-0.8 -2,-0.6 3,-0.6 0.210 29.5 -65.7 -72.2-167.9 12.3 56.5 41.5 112 111 A N T 3 S+ 0 0 36 1,-0.2 19,-2.3 -42,-0.1 20,-0.2 -0.584 113.3 14.6 -79.7 154.4 10.4 59.5 40.0 113 112 A N T 3 S+ 0 0 27 -42,-2.1 2,-0.4 -2,-0.3 -1,-0.2 0.888 89.2 147.6 55.3 38.6 8.6 62.1 42.2 114 113 A V < - 0 0 0 -3,-0.6 -40,-2.3 17,-0.2 2,-0.5 -0.883 37.9-149.9-108.5 136.7 10.4 60.9 45.4 115 114 A S E -pq 74 133C 0 17,-1.8 19,-4.0 -2,-0.4 2,-0.8 -0.958 8.1-169.2-105.0 119.7 11.3 63.2 48.2 116 115 A L E -pq 75 134C 0 -42,-2.3 -40,-2.9 -2,-0.5 19,-0.2 -0.921 29.0-149.1-102.9 96.9 14.4 62.4 50.3 117 116 A A > - 0 0 0 17,-3.2 3,-2.1 -2,-0.8 20,-0.3 -0.118 35.6 -51.3 -73.9 167.4 13.8 64.9 53.1 118 117 A H T 3 S- 0 0 76 1,-0.3 19,-1.9 18,-0.2 -40,-0.2 -0.022 119.8 -3.9 -48.8 130.6 16.5 66.6 55.1 119 118 A Q T 3 S+ 0 0 118 -42,-2.5 -1,-0.3 1,-0.2 -41,-0.1 0.480 95.6 134.1 66.0 13.5 19.2 64.5 56.7 120 119 A S < - 0 0 1 -3,-2.1 -40,-1.6 -43,-0.2 2,-0.3 -0.250 40.0-152.7 -76.6 176.7 17.6 61.2 55.6 121 120 A Q E -gi 80 139A 67 17,-1.6 19,-2.3 -42,-0.2 2,-0.5 -0.961 16.4-164.8-153.4 142.4 19.8 58.5 54.0 122 121 A V E -gi 81 140A 0 -42,-1.7 -40,-1.1 -2,-0.3 2,-0.5 -0.989 16.5-170.3-129.3 114.9 19.2 55.6 51.5 123 122 A H E -gi 82 141A 28 17,-3.2 19,-1.1 -2,-0.5 20,-0.3 -0.946 29.7 -81.4-110.9 124.9 22.0 53.1 51.6 124 123 A G E S+g 83 0A 0 -42,-2.8 -40,-1.3 -2,-0.5 -16,-0.2 -0.254 105.1 62.1 -73.0 157.2 22.2 50.4 48.9 125 124 A P E S+ 0 0 8 0, 0.0 18,-0.8 0, 0.0 17,-0.7 0.326 93.8 117.4 -74.8 127.7 21.2 47.9 48.2 126 125 A A E -hi 108 143A 0 -19,-1.6 -17,-2.6 16,-0.2 2,-0.4 -0.969 42.4-162.6-160.5 151.3 17.9 49.8 48.1 127 126 A A E -hi 109 144A 7 16,-2.1 18,-3.0 -2,-0.3 2,-0.5 -0.987 5.0-163.8-133.9 140.7 15.0 50.9 45.9 128 127 A V E -hi 110 145A 0 -19,-2.4 -17,-2.3 -2,-0.4 18,-0.2 -0.983 21.8-135.0-128.8 115.4 12.5 53.6 46.6 129 128 A G > - 0 0 18 16,-2.6 3,-0.7 -2,-0.5 20,-0.2 -0.112 36.9 -72.3 -69.6 158.1 9.3 53.5 44.4 130 129 A D T 3 S+ 0 0 50 1,-0.2 18,-2.4 17,-0.1 19,-0.2 -0.117 109.8 15.8 -52.4 152.7 7.7 56.5 42.8 131 130 A D T 3 S+ 0 0 36 -19,-2.3 2,-0.4 1,-0.2 -1,-0.2 0.858 88.1 139.1 56.4 37.9 5.8 59.2 44.7 132 131 A T < - 0 0 0 -3,-0.7 -17,-1.8 -20,-0.2 2,-0.6 -0.890 45.9-141.6-113.7 145.3 7.1 58.2 48.1 133 132 A F E -qr 115 150C 4 16,-2.0 18,-3.0 -2,-0.4 2,-0.7 -0.940 7.1-162.4 -99.4 126.4 8.2 60.6 50.8 134 133 A I E -qr 116 151C 0 -19,-4.0 -17,-3.2 -2,-0.6 -14,-0.2 -0.907 30.8-133.8-106.5 109.8 11.3 59.5 52.8 135 134 A G > - 0 0 0 16,-2.7 3,-2.5 -2,-0.7 19,-0.2 -0.002 29.8 -65.4 -65.7 172.7 11.0 61.8 55.9 136 135 A M T 3 S- 0 0 77 1,-0.3 18,-2.2 17,-0.1 -17,-0.2 -0.134 119.4 -0.9 -59.5 133.3 13.5 63.9 57.8 137 136 A Q T 3 S+ 0 0 83 -19,-1.9 -1,-0.3 -20,-0.3 -17,-0.1 0.596 98.7 143.3 63.0 14.8 16.3 61.9 59.4 138 137 A A < - 0 0 3 -3,-2.5 -17,-1.6 -20,-0.2 2,-0.4 -0.292 37.2-145.4 -81.3 176.0 14.7 58.6 58.1 139 138 A F E -ij 121 156A 57 16,-1.7 18,-2.3 -19,-0.2 2,-0.4 -0.996 17.1-177.3-147.2 131.2 16.8 55.6 57.0 140 139 A V E +ij 122 157A 0 -19,-2.3 -17,-3.2 -2,-0.4 2,-0.3 -0.993 16.6 159.5-130.6 129.7 16.4 53.0 54.3 141 140 A F E -ij 123 158A 49 16,-2.6 18,-2.1 -2,-0.4 19,-0.3 -0.985 66.7 -2.6-151.8 133.9 19.0 50.2 53.9 142 141 A K E S+ 0 0 106 -19,-1.1 2,-0.3 -17,-0.7 -16,-0.2 0.880 109.0 112.3 53.5 45.4 18.9 46.7 52.2 143 142 A S E -i 126 0A 4 -18,-0.8 -16,-2.1 -20,-0.3 2,-0.5 -0.943 64.7-137.3-148.5 161.1 15.2 47.4 51.5 144 143 A K E -ik 127 161A 80 16,-2.1 18,-3.6 -2,-0.3 2,-0.6 -0.988 19.0-162.8-120.8 119.1 12.7 48.0 48.8 145 144 A V E -ik 128 162A 3 -18,-3.0 -16,-2.6 -2,-0.5 19,-0.1 -0.947 19.8-134.2-104.6 127.2 10.2 50.8 49.6 146 145 A G > - 0 0 13 16,-1.7 3,-0.6 -2,-0.6 -17,-0.4 0.077 30.8 -77.3 -67.4-173.5 7.1 50.6 47.4 147 146 A N T 3 S+ 0 0 59 1,-0.2 18,-3.0 -19,-0.1 19,-0.2 -0.438 109.5 23.4 -84.8 158.8 5.4 53.5 45.5 148 147 A N T 3 S+ 0 0 80 -18,-2.4 -1,-0.2 16,-0.2 38,-0.2 0.816 91.1 141.0 54.7 41.1 3.1 55.9 47.3 149 148 A C < - 0 0 1 -3,-0.6 -16,-2.0 -19,-0.2 2,-0.4 -0.577 42.1-148.2-105.3 166.8 4.7 55.3 50.7 150 149 A V E -rs 133 167C 8 16,-1.5 18,-2.5 -18,-0.2 2,-0.8 -0.974 5.7-167.9-136.3 112.9 5.5 57.6 53.5 151 150 A L E -rs 134 168C 0 -18,-3.0 -16,-2.7 -2,-0.4 -13,-0.1 -0.938 28.3-144.3 -94.5 110.4 8.4 57.1 55.9 152 151 A E > - 0 0 27 16,-2.3 3,-2.0 -2,-0.8 19,-0.2 -0.261 41.8 -60.1 -67.0 171.1 7.6 59.6 58.6 153 152 A P T 3 S+ 0 0 30 0, 0.0 18,-1.4 0, 0.0 -16,-0.2 -0.146 123.1 6.9 -57.4 137.2 10.5 61.4 60.3 154 153 A R T 3 S+ 0 0 153 -18,-2.2 2,-0.1 16,-0.2 -17,-0.1 0.570 95.2 131.2 64.6 15.6 13.0 59.2 62.0 155 154 A S < - 0 0 2 -3,-2.0 -16,-1.7 13,-0.2 2,-0.3 -0.422 39.1-159.5 -83.4 169.9 11.4 55.9 60.8 156 155 A A E -jl 139 173A 8 16,-2.6 18,-3.1 -18,-0.2 2,-0.4 -0.995 19.4-159.7-152.7 148.4 13.6 53.3 59.2 157 156 A A E +jl 140 174A 0 -18,-2.3 -16,-2.6 -2,-0.3 2,-0.5 -0.991 19.9 174.0-126.9 115.3 13.3 50.3 56.9 158 157 A I E -j 141 0A 52 16,-2.6 -16,-0.2 -2,-0.4 -15,-0.1 -0.984 68.0 -13.2-130.3 116.2 16.3 47.8 57.1 159 158 A G S S+ 0 0 47 -18,-2.1 2,-0.3 -2,-0.5 -16,-0.2 0.719 109.8 106.1 71.7 29.1 16.3 44.4 55.3 160 159 A V - 0 0 3 -19,-0.3 -16,-2.1 14,-0.2 2,-0.5 -0.817 68.4-124.5-133.4 171.6 12.6 44.6 54.4 161 160 A T E -k 144 0A 69 -2,-0.3 -16,-0.2 -18,-0.2 -3,-0.0 -0.970 22.9-152.4-114.6 118.4 10.1 45.2 51.5 162 161 A I E -k 145 0A 1 -18,-3.6 -16,-1.7 -2,-0.5 3,-0.1 -0.869 23.1-128.4 -92.1 115.9 7.6 48.0 52.3 163 162 A P > - 0 0 34 0, 0.0 3,-1.1 0, 0.0 -17,-0.1 -0.377 36.5 -79.2 -60.6 158.5 4.4 47.3 50.3 164 163 A D T 3 S+ 0 0 92 1,-0.2 -16,-0.2 -19,-0.1 3,-0.1 -0.065 110.4 15.3 -56.9 145.6 2.9 50.0 48.1 165 164 A G T 3 S+ 0 0 17 -18,-3.0 21,-2.8 1,-0.2 2,-0.3 0.667 94.6 122.4 64.8 18.1 0.8 52.7 49.7 166 165 A R B < -V 185 0F 62 -3,-1.1 -16,-1.5 19,-0.3 2,-0.3 -0.731 45.8-146.7-104.1 166.2 1.9 52.1 53.4 167 166 A Y E -s 150 0C 52 17,-2.2 -16,-0.2 -2,-0.3 -18,-0.0 -0.887 7.9-138.7-129.0 156.5 3.5 54.4 55.9 168 167 A I E -s 151 0C 0 -18,-2.5 -16,-2.3 -2,-0.3 -13,-0.2 -0.965 31.6-119.4-113.2 114.6 6.0 53.9 58.8 169 168 A P > - 0 0 42 0, 0.0 3,-2.1 0, 0.0 14,-0.0 -0.236 44.3 -81.4 -47.9 139.9 5.1 55.9 62.0 170 169 A A T 3 S+ 0 0 56 1,-0.3 -16,-0.2 -15,-0.1 3,-0.1 -0.123 114.9 12.4 -46.5 140.6 7.7 58.5 63.1 171 170 A G T 3 S+ 0 0 45 -18,-1.4 2,-0.4 -19,-0.2 -1,-0.3 0.240 92.3 132.2 78.6 -17.4 10.6 56.8 65.1 172 171 A M < - 0 0 66 -3,-2.1 -16,-2.6 -4,-0.0 2,-0.7 -0.536 43.6-155.7 -79.9 128.7 9.7 53.2 64.2 173 172 A V E -l 156 0A 80 -2,-0.4 2,-0.6 -18,-0.2 -16,-0.2 -0.885 7.6-159.2-101.8 108.9 12.5 51.0 63.0 174 173 A V E +l 157 0A 0 -18,-3.1 -16,-2.6 -2,-0.7 -14,-0.2 -0.838 27.0 154.3 -94.7 113.1 11.2 48.2 60.8 175 174 A T + 0 0 83 -2,-0.6 2,-0.4 -18,-0.2 -1,-0.1 0.441 53.4 62.9-120.3 1.6 13.6 45.2 60.6 176 175 A S S > S- 0 0 44 1,-0.1 4,-2.4 -16,-0.0 5,-0.2 -0.945 71.0-133.2-133.7 145.5 11.4 42.3 59.8 177 176 A Q H > S+ 0 0 75 -2,-0.4 4,-2.7 1,-0.2 5,-0.2 0.915 107.5 61.7 -60.2 -32.1 9.2 41.3 56.9 178 177 A A H > S+ 0 0 69 1,-0.2 4,-0.9 2,-0.2 -1,-0.2 0.936 108.9 41.0 -57.9 -50.1 6.5 40.4 59.4 179 178 A E H >4 S+ 0 0 74 2,-0.2 3,-0.8 1,-0.2 -1,-0.2 0.906 112.2 54.5 -68.5 -41.1 6.3 44.0 60.7 180 179 A A H >< S+ 0 0 0 -4,-2.4 3,-1.5 1,-0.3 -2,-0.2 0.887 105.2 55.8 -58.3 -39.9 6.6 45.5 57.2 181 180 A D H 3< S+ 0 0 81 -4,-2.7 -1,-0.3 1,-0.3 -2,-0.2 0.794 106.8 50.3 -59.6 -35.4 3.6 43.5 56.1 182 181 A K T << S+ 0 0 174 -4,-0.9 -1,-0.3 -3,-0.8 -2,-0.2 0.244 79.6 129.7 -87.8 7.7 1.5 44.9 59.0 183 182 A L < - 0 0 7 -3,-1.5 -15,-0.1 -4,-0.2 -3,-0.0 -0.369 63.9-102.0 -64.6 156.0 2.3 48.6 58.4 184 183 A P - 0 0 50 0, 0.0 -17,-2.2 0, 0.0 2,-0.3 -0.120 36.0-111.7 -71.0 156.0 -0.7 50.9 58.2 185 184 A E B -V 166 0F 127 -19,-0.3 2,-0.3 -36,-0.1 -19,-0.3 -0.757 21.7-113.8 -89.9 147.3 -2.1 52.2 54.9 186 185 A V + 0 0 38 -21,-2.8 2,-0.3 -2,-0.3 -1,-0.0 -0.609 43.5 178.8 -74.7 124.2 -2.0 55.7 53.5 187 186 A T > - 0 0 54 -2,-0.3 3,-1.9 1,-0.0 6,-0.1 -0.866 45.4 -99.0-122.3 169.3 -5.6 56.9 53.4 188 187 A D T 3 S+ 0 0 137 -2,-0.3 5,-0.1 1,-0.3 6,-0.1 0.828 123.3 48.3 -52.7 -38.3 -7.0 60.3 52.3 189 188 A D T 3 S+ 0 0 141 4,-0.1 -1,-0.3 3,-0.1 2,-0.1 0.538 82.0 116.7 -83.5 -5.2 -7.3 61.4 56.0 190 189 A Y S X S- 0 0 19 -3,-1.9 3,-2.3 1,-0.1 4,-0.3 -0.418 74.7-120.6 -68.9 142.6 -3.8 60.3 57.1 191 190 A A T 3 S+ 0 0 87 1,-0.3 3,-0.3 2,-0.1 -1,-0.1 0.797 111.1 37.3 -53.8 -35.7 -1.6 63.3 58.2 192 191 A Y T >> S+ 0 0 64 1,-0.2 3,-0.7 2,-0.1 4,-0.6 0.204 82.9 111.6-101.0 17.3 1.1 62.8 55.5 193 192 A S T <4 S+ 0 0 27 -3,-2.3 4,-0.2 1,-0.3 -1,-0.2 0.863 90.2 27.6 -61.5 -32.9 -1.3 61.7 52.7 194 193 A H T 3> S+ 0 0 131 -3,-0.3 4,-1.6 -4,-0.3 -1,-0.3 0.351 95.1 98.4-105.6 1.6 -0.7 64.9 50.7 195 194 A T H <> S+ 0 0 37 -3,-0.7 4,-2.1 1,-0.2 5,-0.2 0.925 79.1 50.9 -55.6 -48.9 2.8 65.7 51.8 196 195 A N H X S+ 0 0 10 -4,-0.6 4,-2.9 1,-0.2 5,-0.3 0.928 108.4 49.6 -62.2 -43.3 4.8 64.2 48.9 197 196 A E H > S+ 0 0 127 1,-0.2 4,-2.2 -4,-0.2 -1,-0.2 0.889 112.3 48.9 -62.6 -39.3 3.0 65.8 46.1 198 197 A A H X S+ 0 0 57 -4,-1.6 4,-2.6 2,-0.2 -1,-0.2 0.910 112.6 47.8 -60.9 -47.7 3.3 69.2 47.7 199 198 A V H X S+ 0 0 27 -4,-2.1 4,-2.7 -5,-0.2 -2,-0.2 0.891 111.7 49.7 -63.8 -38.5 7.1 68.7 48.3 200 199 A V H X S+ 0 0 16 -4,-2.9 4,-3.0 2,-0.2 5,-0.3 0.948 110.7 49.7 -69.8 -40.8 7.7 67.6 44.8 201 200 A Y H X S+ 0 0 157 -4,-2.2 4,-1.8 -5,-0.3 -2,-0.2 0.947 114.1 46.2 -60.0 -47.9 5.8 70.6 43.3 202 201 A V H X S+ 0 0 75 -4,-2.6 4,-2.4 -5,-0.2 -1,-0.2 0.940 113.8 47.0 -58.3 -55.0 7.8 72.9 45.5 203 202 A N H X S+ 0 0 14 -4,-2.7 4,-2.6 2,-0.2 5,-0.2 0.868 107.9 54.3 -63.9 -37.7 11.2 71.2 44.7 204 203 A V H X S+ 0 0 35 -4,-3.0 4,-2.1 -5,-0.2 -1,-0.2 0.952 113.2 45.4 -57.4 -44.3 10.6 71.1 41.0 205 204 A H H X S+ 0 0 103 -4,-1.8 4,-2.5 -5,-0.3 -2,-0.2 0.903 112.1 50.5 -67.2 -36.3 10.0 74.9 41.2 206 205 A L H X S+ 0 0 74 -4,-2.4 4,-3.1 -5,-0.2 5,-0.3 0.927 107.1 54.8 -66.1 -40.5 13.0 75.5 43.5 207 206 A A H X S+ 0 0 0 -4,-2.6 4,-2.6 -157,-0.2 -2,-0.2 0.958 111.4 45.0 -58.2 -44.0 15.2 73.6 41.0 208 207 A E H X S+ 0 0 81 -4,-2.1 4,-1.6 2,-0.2 -2,-0.2 0.959 114.3 47.3 -67.1 -45.1 14.1 75.9 38.2 209 208 A G H < S+ 0 0 35 -4,-2.5 4,-0.2 1,-0.2 -1,-0.2 0.928 114.1 47.8 -59.4 -47.2 14.5 79.1 40.3 210 209 A Y H >< S+ 0 0 99 -4,-3.1 3,-2.2 -5,-0.2 4,-0.4 0.930 106.0 58.1 -64.6 -33.7 17.9 78.0 41.5 211 210 A K H >< S+ 0 0 64 -4,-2.6 3,-1.1 -5,-0.3 -1,-0.2 0.837 99.6 59.5 -61.8 -30.6 18.9 77.1 37.9 212 211 A E T 3< S+ 0 0 143 -4,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.540 100.3 57.3 -77.4 -0.7 18.2 80.7 37.0 213 212 A T T < 0 0 100 -3,-2.2 -1,-0.2 -4,-0.2 -2,-0.2 0.448 360.0 360.0-104.6 -5.9 20.8 81.9 39.6 214 213 A S < 0 0 135 -3,-1.1 -2,-0.2 -4,-0.4 -1,-0.1 0.508 360.0 360.0-102.9 360.0 23.7 79.9 38.1